Patent | Date |
---|
Compositions And Methods For Modulating Ttr Expression App 20220275365 - Prakash; Thazha P. ;   et al. | 2022-09-01 |
Compounds And Methods For Modulating Tmprss6 Expression App 20220259600 - Guo; Shuling ;   et al. | 2022-08-18 |
Modified CRISPR RNA and modified single CRISPR RNA and uses thereof Grant 11,414,657 - Rahdar , et al. August 16, 2 | 2022-08-16 |
Methods And Compositions For Inhibiting Pmp22 Expression App 20220251553 - Hung; Gene ;   et al. | 2022-08-11 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20220162603 - Allerson; Charles ;   et al. | 2022-05-26 |
Modified compounds and uses thereof Grant 11,332,733 - Seth , et al. May 17, 2 | 2022-05-17 |
Modulators of diacyglycerol acyltransferase 2 (DGAT2) Grant 11,312,962 - Bhanot , et al. April 26, 2 | 2022-04-26 |
Compositions and methods for modulating growth hormone receptor expression Grant 11,312,964 - Prakash , et al. April 26, 2 | 2022-04-26 |
Conjugated antisense compounds and their use Grant 11,299,736 - Prakash , et al. April 12, 2 | 2022-04-12 |
5' modified nucleosides and oligomeric compounds prepared therefrom Grant 11,268,094 - Prakash , et al. March 8, 2 | 2022-03-08 |
Modulation Of Hepatitis B Virus (hbv) Expression App 20220064650 - SWAYZE; Eric E. ;   et al. | 2022-03-03 |
Selective antisense compounds and uses thereof Grant 11,236,335 - Oestergaard , et al. February 1, 2 | 2022-02-01 |
Conjugated Antisense Compounds And Their Use App 20220023429 - Seth; Punit P. ;   et al. | 2022-01-27 |
Oligomer-conjugate Complexes And Their Use App 20220025370 - Prakash; Thazha P. ;   et al. | 2022-01-27 |
Compounds And Methods For Modulation Of Dystrophia Myotonica-protein Kinase (dmpk) Expression App 20210403916 - Swayze; Eric E. ;   et al. | 2021-12-30 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression App 20210395734 - Prakash; Thazha P. ;   et al. | 2021-12-23 |
Chirally Enriched Oligomeric Compounds App 20210380976 - Seth; Punit P. ;   et al. | 2021-12-09 |
Modified compounds and uses thereof Grant 11,149,264 - Seth , et al. October 19, 2 | 2021-10-19 |
Methods and compositions for inhibiting PMP22 expression Grant 11,136,577 - Hung , et al. October 5, 2 | 2021-10-05 |
Conjugated antisense compounds and their use Grant 11,116,843 - Seth , et al. September 14, 2 | 2021-09-14 |
Compositions and Methods for Modulating PKK Expression App 20210277401 - Prakash; Thazha P. ;   et al. | 2021-09-09 |
Oligomer-conjugate complexes and their use Grant 11,104,899 - Prakash , et al. August 31, 2 | 2021-08-31 |
Modified Compounds and Uses Thereof App 20210261945 - Seth; Punit P. ;   et al. | 2021-08-26 |
Linkage Modified Oligomeric Compounds App 20210254059 - Migawa; Michael T. ;   et al. | 2021-08-19 |
Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom Grant 11,084,844 - Prakash , et al. August 10, 2 | 2021-08-10 |
Selective Antisense Compounds and Uses Thereof App 20210238591 - Seth; Punit P. ;   et al. | 2021-08-05 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 11,078,485 - Allerson , et al. August 3, 2 | 2021-08-03 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20210207146 - Prakash; Thazha P. ;   et al. | 2021-07-08 |
Oligomeric Compounds Comprising Bicyclic Nucleotides and Uses Thereof App 20210147837 - Freier; Susan M. ;   et al. | 2021-05-20 |
Selective Antisense Compounds and Uses Thereof App 20210147838 - Seth; Punit P. ;   et al. | 2021-05-20 |
Modulators of PCSK9 expression Grant 11,000,595 - Swayze , et al. May 11, 2 | 2021-05-11 |
Compositions And Methods App 20210130823 - Prakash; Thazha P. ;   et al. | 2021-05-06 |
Compositions for modulating SOD-1 expression Grant 10,968,453 - Swayze April 6, 2 | 2021-04-06 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION App 20210087566 - PRAKASH; Thazha P. ;   et al. | 2021-03-25 |
Compounds and methods for modulation of dystrophia myotonica-protein kinase (DMPK) expression Grant 10,954,519 - Swayze , et al. March 23, 2 | 2021-03-23 |
Modulators of PCSK9 Expression App 20210077630 - Swayze; Eric E. ;   et al. | 2021-03-18 |
Compositions For Modulating Tau Expression App 20210071176 - Kordasiewicz; Holly ;   et al. | 2021-03-11 |
Conjugated Antisense Compounds And Their Use App 20210052631 - Prakash; Thazha P. ;   et al. | 2021-02-25 |
Conjugated Antisense Compounds And Their Use App 20210054017 - Seth; Punit P. ;   et al. | 2021-02-25 |
Compositions and methods for modulating apolipoprotein C-III expression Grant 10,927,372 - Prakash , et al. February 23, 2 | 2021-02-23 |
Compositions And Methods For Modulating Ttr Expression App 20210024923 - Prakash; Thazha P. ;   et al. | 2021-01-28 |
Modified Compounds And Uses Thereof App 20210017513 - Seth; Punit P. ;   et al. | 2021-01-21 |
Selective Antisense Compounds and Uses Thereof App 20210002636 - Oestergaard; Michael ;   et al. | 2021-01-07 |
Compositions and methods for modulating apolipoprotein (a) expression Grant 10,883,104 - Prakash , et al. January 5, 2 | 2021-01-05 |
Compositions and methods for modulating angiopoietin-like 3 expression Grant 10,875,884 - Prakash , et al. December 29, 2 | 2020-12-29 |
Oligomeric Compounds Comprising Bicyclic Nucleotides and Uses Thereof App 20200392493 - Freier; Susan M. ;   et al. | 2020-12-17 |
Oligomeric compounds comprising .alpha.-.beta.-constrained nucleic acid Grant 10,865,413 - Oestergaard , et al. December 15, 2 | 2020-12-15 |
Modulation Of Signal Transducer And Activator Of Transcription 3 (stat3) Expression App 20200385716 - SWAYZE; Eric E. ;   et al. | 2020-12-10 |
5' Modified Nucleosides And Oligomeric Compounds Prepared Therefrom App 20200385722 - Prakash; Thazha P. ;   et al. | 2020-12-10 |
Selective Reduction of Allelic Variants App 20200377946 - Bennett; C. Frank ;   et al. | 2020-12-03 |
Conjugated antisense compounds and their use Grant 10,844,379 - Prakash , et al. November 24, 2 | 2020-11-24 |
Compositions For Modulating Sod-1 Expression App 20200354723 - Swayze; Eric E. | 2020-11-12 |
Compositions and methods for modulating growth hormone receptor expression Grant 10,793,862 - Prakash , et al. October 6, 2 | 2020-10-06 |
Compositions for modulating Tau expression Grant 10,793,856 - Kordasiewicz , et al. October 6, 2 | 2020-10-06 |
Antisense Compounds App 20200276221 - Swayze; Eric E. | 2020-09-03 |
Single-Stranded RNAI Oligonucleotides Targeting APOC-III App 20200270609 - Prakash; Thazha P. ;   et al. | 2020-08-27 |
Method for synthesis of reactive conjugate clusters Grant 10,751,419 - Migawa , et al. A | 2020-08-25 |
Compositions For Modulating C9orf72 Expression App 20200239882 - Bennett; C. Frank ;   et al. | 2020-07-30 |
Compositions And Methods For Modulating Hbv Expression App 20200224198 - PRAKASH; Thazha P. ;   et al. | 2020-07-16 |
Modulators of PCSK9 Expression App 20200197525 - Swayze; Eric E. ;   et al. | 2020-06-25 |
Modulation Of Hepatitis B Virus (hbv) Expression App 20200190520 - Swayze; Eric E. ;   et al. | 2020-06-18 |
Compounds And Methods For Modulating Tmprss6 Expression App 20200190522 - Guo; Shuling ;   et al. | 2020-06-18 |
Compositions and methods for modulating TTR expression Grant 10,683,499 - Prakash , et al. | 2020-06-16 |
5' modified nucleosides and oligomeric compounds prepared therefrom Grant 10,676,738 - Prakash , et al. | 2020-06-09 |
Compositions for modulating SOD-1 expression Grant 10,669,546 - Swayze | 2020-06-02 |
Compositions And Methods For Enhanced Intestinal Absorption Of Conjugated Oligomeric Compounds App 20200157548 - Prakash; Thazha P. ;   et al. | 2020-05-21 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20200123551 - Prakash; Thazha P. ;   et al. | 2020-04-23 |
Conjugated antisense compounds and their use Grant 10,570,169 - Seth , et al. Feb | 2020-02-25 |
Selective Antisense Compounds And Uses Thereof App 20200056187 - Oestergaard; Michael ;   et al. | 2020-02-20 |
Compositions And Methods For Modulating Pkk Expression App 20200056185 - Prakash; Thazha P. ;   et al. | 2020-02-20 |
Compositions And Methods For Modulating Complement Factor B Expression App 20200048638 - Prakash; Thazha P. ;   et al. | 2020-02-13 |
Modulators Of Diacyglycerol Acyltransferase 2 (dgat2) App 20200040341 - Bhanot; Sanjay ;   et al. | 2020-02-06 |
Compositions For Modulating Sod-1 Expression App 20200040342 - Swayze; Eric E. | 2020-02-06 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20200017855 - Allerson; Charles ;   et al. | 2020-01-16 |
Modulators of PCSK9 expression Grant 10,517,953 - Swayze , et al. Dec | 2019-12-31 |
Modified Crispr Rna And Uses Thereof App 20190382751 - Radhar; Meghdad ;   et al. | 2019-12-19 |
Conjugated Antisense Compounds And Their Use App 20190367914 - Prakash; Thazha P. ;   et al. | 2019-12-05 |
Antisense compounds Grant 10,493,092 - Swayze De | 2019-12-03 |
Oligomeric Compounds Comprising Alpha-beta-constrained Nucleic Acid App 20190359979 - Oestergaard; Michael ;   et al. | 2019-11-28 |
Modulation of signal transducer and activator of transcription 3 (STAT3) expression Grant 10,479,993 - Swayze , et al. Nov | 2019-11-19 |
Selective Antisense Compounds And Uses Thereof App 20190338281 - Seth; Punit P. ;   et al. | 2019-11-07 |
Methods and compounds useful in conditions related to repeat expansion Grant 10,435,430 - Prakash , et al. O | 2019-10-08 |
Compounds and methods for modulating TMPRSS6 expression Grant 10,415,038 - Guo , et al. Sept | 2019-09-17 |
Selective Antisense Compounds And Uses Thereof App 20190276823 - Oestergaard; Michael ;   et al. | 2019-09-12 |
Compounds And Methods For Modulation Of Dystrophia Myotonica-protein Kinase (dmpk) Expression App 20190276832 - Swayze; Eric E. ;   et al. | 2019-09-12 |
Antisense Compounds And Uses Thereof App 20190270990 - Kordasiewicz; Holly ;   et al. | 2019-09-05 |
Compositions for modulating SOD-1 expression Grant 10,385,341 - Swayze A | 2019-08-20 |
Method For Synthesis Of Reactive Conjugate Clusters App 20190209694 - Migawa; Michael T. ;   et al. | 2019-07-11 |
Linkage modified oligomeric compounds Grant 10,344,275 - Wan , et al. July 9, 2 | 2019-07-09 |
Oligomeric compounds comprising bicyclic nucleotides and uses thereof Grant 10,337,007 - Freier , et al. | 2019-07-02 |
Oligomeric Compounds Comprising Bicyclic Nucleotides And Uses Thereof App 20190169610 - Freier; Susan M. ;   et al. | 2019-06-06 |
Compositions and methods for modulating PKK expression Grant 10,294,477 - Swayze | 2019-05-21 |
Oligomer-conjugate Complexes And Their Use App 20190136234 - Prakash; Thazha P. ;   et al. | 2019-05-09 |
Compositions and methods for modulating complement factor B expression Grant 10,280,423 - Prakash , et al. | 2019-05-07 |
Single-stranded Rnai Oligonucleotides Targeting Apoc-iii App 20190127737 - Prakash; Thazha P. ;   et al. | 2019-05-02 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 10,266,825 - Allerson , et al. | 2019-04-23 |
Selective antisense compounds and uses thereof Grant 10,260,069 - Oestergaard , et al. | 2019-04-16 |
Oligomeric compounds comprising alpha-beta-constrained nucleic acid Grant 10,221,416 - Oestergaard , et al. | 2019-03-05 |
Methods And Compositions For Inhibiting Pmp22 Expression App 20190062741 - Hung; Gene ;   et al. | 2019-02-28 |
Oligomeric Compounds and Compositions for use in Modulation of Small Non-Coding RNAs App 20190062744 - Esau; Christine ;   et al. | 2019-02-28 |
Compositions And Methods For Modulating Hbv Expression App 20190055554 - Prakash; Thazha P. ;   et al. | 2019-02-21 |
Selective antisense compounds and uses thereof Grant 10,202,599 - Seth , et al. Feb | 2019-02-12 |
Compositions And Methods For Modulating Angiopoietin-like 3 Expression App 20190016748 - Prakash; Thazha P. ;   et al. | 2019-01-17 |
Selective Reduction Of Allelic Variants App 20190002877 - Bennett; C. Frank ;   et al. | 2019-01-03 |
Modified Nucleosides, Analogs Thereof And Oligomeric Compounds Prepared Therefrom App 20180371005 - Prakash; Thazha P. ;   et al. | 2018-12-27 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20180320188 - Prakash; Thazha P. ;   et al. | 2018-11-08 |
Modulators of PCSK9 Expression App 20180311365 - Swayze; Eric E. ;   et al. | 2018-11-01 |
Modulators Of Diacyglycerol Acyltransferase 2 (dgat2) App 20180312845 - Bhanot; Sanjay ;   et al. | 2018-11-01 |
Linkage Modified Oligomeric Compounds App 20180305687 - Wan; W. Brad ;   et al. | 2018-10-25 |
Method for synthesis of reactive conjugate clusters Grant 10,098,959 - Migawa , et al. October 16, 2 | 2018-10-16 |
Selective Reduction Of Allelic Variants App 20180291453 - Bennett; C. Frank ;   et al. | 2018-10-11 |
Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom Grant 10,087,210 - Prakash , et al. October 2, 2 | 2018-10-02 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression App 20180273952 - Prakash; Thazha P. ;   et al. | 2018-09-27 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION App 20180273953 - Prakash; Thazha P. ;   et al. | 2018-09-27 |
Conjugated Antisense Compounds And Their Use App 20180256729 - Seth; Punit P. ;   et al. | 2018-09-13 |
Oligomeric Compounds Comprising Bicyclic Nucleotides And Uses Thereof App 20180251761 - Freier; Susan M. ;   et al. | 2018-09-06 |
Compositions And Methods For Enhanced Intestinal Absorption Of Conjugated Oligomeric Compounds App 20180245084 - Prakash; Thazha P. ;   et al. | 2018-08-30 |
Bicyclic carbocyclic nucleosides and oligomeric compounds prepared therefrom Grant 10,036,019 - Seth , et al. July 31, 2 | 2018-07-31 |
Oligomer-conjugate complexes and their use Grant 10,023,861 - Prakash , et al. July 17, 2 | 2018-07-17 |
Modified Crispr Rna And Modified Single Crispr Rna And Uses Thereof App 20180179521 - Rahdar; Meghdad ;   et al. | 2018-06-28 |
Compositions and methods for modulating growth hormone receptor expression Grant 9,994,855 - Prakash , et al. June 12, 2 | 2018-06-12 |
Methods and compounds useful in conditions related to repeat expansion Grant 9,976,138 - Prakash , et al. May 22, 2 | 2018-05-22 |
Compositions and methods for modulating angiopoietin-like 3 expression Grant 9,957,292 - Prakash , et al. May 1, 2 | 2018-05-01 |
Compositions and methods for modulating apolipoprotein (a) expression Grant 9,957,504 - Prakash , et al. May 1, 2 | 2018-05-01 |
Compounds And Methods For Modulating Tmprss6 Expression App 20180105817 - Guo; Shuling ;   et al. | 2018-04-19 |
Compositions For Modulating Tau Expression App 20180094261 - Kordasiewicz; Holly ;   et al. | 2018-04-05 |
Compositions and methods for modulating apolipoprotein C-III expression Grant 9,932,581 - Prakash , et al. April 3, 2 | 2018-04-03 |
Compositions and methods for modulating HBV expression Grant 9,932,580 - Prakash , et al. April 3, 2 | 2018-04-03 |
Linkage modified oligomeric compounds Grant 9,926,556 - Wan , et al. March 27, 2 | 2018-03-27 |
Oligomeric compounds comprising bicyclic nucleotides and uses thereof Grant 9,914,922 - Freier , et al. March 13, 2 | 2018-03-13 |
Compositions And Methods For Modulating Ttr Expression App 20180044676 - Prakash; Thazha P. ;   et al. | 2018-02-15 |
Compositions And Methods App 20180002693 - Prakash; Thazha P. ;   et al. | 2018-01-04 |
Modulation Of Hepatitis B Virus (hbv) Expression App 20170369883 - Swayze; Eric E. ;   et al. | 2017-12-28 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20170369880 - Allerson; Charles ;   et al. | 2017-12-28 |
Conjugated Antisense Compounds And Their Use App 20170355727 - Seth; Punit P. ;   et al. | 2017-12-14 |
Selective Antisense Compounds And Uses Thereof App 20170327824 - Oestergaard; Michael ;   et al. | 2017-11-16 |
Phosphorous-linked oligomeric compounds and their use in gene modulation Grant 9,771,578 - Baker , et al. September 26, 2 | 2017-09-26 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas App 20170268002 - Esau; Christine ;   et al. | 2017-09-21 |
Gapped oligomeric compounds comprising 5'-modified deoxyribonucleosides in the gap and uses thereof Grant 9,752,142 - Oestergaard , et al. September 5, 2 | 2017-09-05 |
Oligomeric compounds and methods Grant 9,738,895 - Swayze , et al. August 22, 2 | 2017-08-22 |
5'-end derivatives Grant 9,725,479 - Manoharan , et al. August 8, 2 | 2017-08-08 |
Compositions and methods Grant 9,714,421 - Prakash , et al. July 25, 2 | 2017-07-25 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 9,708,610 - Allerson , et al. July 18, 2 | 2017-07-18 |
Oligomeric compounds comprising bicyclic nucleosides and uses thereof Grant 9,695,418 - Seth , et al. July 4, 2 | 2017-07-04 |
Compositions And Methods For Modulating Pkk Expression App 20170183661 - Prakash; Thazha P. ;   et al. | 2017-06-29 |
Antisense Compounds App 20170182082 - Swayze; Eric E. | 2017-06-29 |
Bicyclic morpholino compounds and oligomeric compounds prepared therefrom Grant 9,688,707 - Seth , et al. June 27, 2 | 2017-06-27 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20170166899 - Prakash; Thazha P. ;   et al. | 2017-06-15 |
Modulation of hepatitis B virus (HBV) expression Grant 9,677,076 - Swayze , et al. June 13, 2 | 2017-06-13 |
Compositions And Methods For Modulating Complement Factor B Expression App 20170159055 - Prakash; Thazha P. ;   et al. | 2017-06-08 |
Compositions And Methods For Enhanced Intestinal Absorption Of Conjugated Oligomeric Compounds App 20170145424 - Prakash; Thazha P. ;   et al. | 2017-05-25 |
Bicyclic Carbocyclic Nucleosides And Oligomeric Compounds Prepared Therefrom App 20170145409 - Seth; Punit P. ;   et al. | 2017-05-25 |
Linkage Modified Gapped Oligomeric Compounds And Uses Thereof App 20170130224 - Oestergaard; Michael ;   et al. | 2017-05-11 |
Compounds and methods for modulating gene expression Grant 9,617,540 - Bhanot , et al. April 11, 2 | 2017-04-11 |
Method For Synthesis Of Reactive Conjugate Clusters App 20170043025 - Migawa; Michael T. ;   et al. | 2017-02-16 |
Linkage Modified Oligomeric Compounds App 20170044526 - Wan; W. Brad ;   et al. | 2017-02-16 |
Oligomeric Compounds Comprising Alpha-beta-constrained Nucleic Acid App 20170044539 - Oestergaard; Michael ;   et al. | 2017-02-16 |
Compositions For Modulating Sod-1 Expression App 20170037410 - Swayze; Eric E. ;   et al. | 2017-02-09 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas App 20170037402 - Esau; Christine ;   et al. | 2017-02-09 |
Antisense compounds Grant 9,550,988 - Swayze January 24, 2 | 2017-01-24 |
Modulation Of Signal Transducer And Activator Of Transcription 3 (stat3) Expression App 20160348104 - Swayze; Eric E. ;   et al. | 2016-12-01 |
Compounds And Methods For Modulation Of Dystrophia Myotonica-protein Kinase (dmpk) Expression App 20160304877 - Swayze; Eric E. ;   et al. | 2016-10-20 |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAS Grant 9,447,412 - Gordon , et al. September 20, 2 | 2016-09-20 |
Oligomeric compounds comprising tricyclic nucleosides and methods for their use Grant 9,428,750 - Swayze , et al. August 30, 2 | 2016-08-30 |
Cyclohexenyl nucleic acids analogs Grant 9,409,934 - Seth , et al. August 9, 2 | 2016-08-09 |
Compositions And Methods For Modulating Angiopoietin-like 3 Expression App 20160194349 - Prakash; Thazha P. ;   et al. | 2016-07-07 |
Compositions and methods for modulating angiopoietin-like 3 expression Grant 9,382,540 - Prakash , et al. July 5, 2 | 2016-07-05 |
Modified Nucleosides, Analogs Thereof And Oligomeric Compounds Prepared Therefrom App 20160186185 - Prakash; Thazah P. ;   et al. | 2016-06-30 |
Substituted Morpholino Compounds Analogs Thereof And Oligomeric Compounds Prepared Therefrom App 20160186174 - Seth; Punit P. ;   et al. | 2016-06-30 |
Bicyclic Morpholino Compounds And Oligomeric Compounds Prepared Therefrom App 20160186175 - Seth; Punit P. ;   et al. | 2016-06-30 |
Methods And Compounds Useful In Conditions Related To Repeat Expansion App 20160159846 - Prakash; Thazha P. ;   et al. | 2016-06-09 |
Modulation of signal transducer and activator of transcription 3 (STAT3) expression Grant 9,359,608 - Swayze , et al. June 7, 2 | 2016-06-07 |
Compositions For Modulating Tau Expression App 20160145617 - Kordasiewicz; Holly ;   et al. | 2016-05-26 |
Antisense Compounds And Uses Thereof App 20160138014 - Kordasiewicz; Holly ;   et al. | 2016-05-19 |
Compositions And Methods For Modulation Of Target Nucleic Acids App 20160122761 - Prakash; Thazha P. ;   et al. | 2016-05-05 |
Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom Grant 9,321,799 - Prakash , et al. April 26, 2 | 2016-04-26 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION App 20160090596 - Prakash; Thazha P. ;   et al. | 2016-03-31 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression App 20160090595 - Prakash; Thazha P. ;   et al. | 2016-03-31 |
Oligomeric compounds having at least one neutrally linked terminal bicyclic nucleoside Grant 9,290,534 - Seth , et al. March 22, 2 | 2016-03-22 |
Compositions And Methods App 20160076032 - Prakash; Thazha P. ;   et al. | 2016-03-17 |
Compositions And Methods For Modulating Hbv Expression App 20160076030 - Prakash; Thazha P. ;   et al. | 2016-03-17 |
Phosphorous-linked Oligomeric Compounds And Their Use In Gene Modulation App 20160076031 - Baker; Brenda F. ;   et al. | 2016-03-17 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20160053261 - Allerson; Charles ;   et al. | 2016-02-25 |
Modulation Of Hepatitis B Virus (hbv) Expression App 20160046945 - Swayze; Eric E. ;   et al. | 2016-02-18 |
5' Modified Nucleosides And Oligomeric Compounds Prepared Therefrom App 20160046939 - Prakash; Thazha P. ;   et al. | 2016-02-18 |
Chimeric Oligomeric Compounds And Their Use In Gene Modulation App 20160017324 - Baker; Brenda F. ;   et al. | 2016-01-21 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas App 20160017329 - Esau; Christine ;   et al. | 2016-01-21 |
Conjugated Antisense Compounds And Their Use App 20160017323 - Prakash; Thazha P. ;   et al. | 2016-01-21 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20160017328 - Bhat; Balkrishen ;   et al. | 2016-01-21 |
Oligomeric Compounds And Excipients App 20160010086 - BENNETT; C. FRANK ;   et al. | 2016-01-14 |
Selective Antisense Compounds And Uses Thereof App 20150376625 - Oestergaard; Michael ;   et al. | 2015-12-31 |
Tricyclic nucleic acid analogs Grant 9,221,864 - Seth , et al. December 29, 2 | 2015-12-29 |
Compounds And Methods For Modulating Gene Expression App 20150344879 - Bhanot; Sanjay ;   et al. | 2015-12-03 |
5'-substituted bicyclic nucleosides and oligomeric compounds prepared therefrom Grant 9,193,752 - Migawa , et al. November 24, 2 | 2015-11-24 |
Selective Reduction Of Allelic Variants App 20150329859 - Bennett; C. Frank ;   et al. | 2015-11-19 |
Oligomeric Compounds And Compositions For The Use In Modulation Of Micrornas App 20150322436 - Esau; Christine ;   et al. | 2015-11-12 |
Compositions and methods for modulating apolipoprotein (a) expression Grant 9,181,550 - Prakash , et al. November 10, 2 | 2015-11-10 |
Conjugated antisense compounds and their use Grant 9,181,549 - Prakash , et al. November 10, 2 | 2015-11-10 |
Compositions And Methods For Modulating Angiopoietin-like 3 Expression App 20150315594 - Prakash; Thazha P. ;   et al. | 2015-11-05 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20150315579 - Bhat; Balkrishen ;   et al. | 2015-11-05 |
Compositions and methods for modulating apolipoprotein C-III expression Grant 9,163,239 - Prakash , et al. October 20, 2 | 2015-10-20 |
Selective Reduction Of Allelic Variants App 20150292015 - Bennett; C. Frank ;   et al. | 2015-10-15 |
Modified 5' diphosphate nucleosides and oligomeric compounds prepared therefrom Grant 9,156,873 - Prakash , et al. October 13, 2 | 2015-10-13 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 9,150,606 - Allerson , et al. October 6, 2 | 2015-10-06 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 9,150,605 - Allerson , et al. October 6, 2 | 2015-10-06 |
Selective Antisense Compounds And Uses Thereof App 20150275208 - Oestergaard; Michael ;   et al. | 2015-10-01 |
Compositions and methods for modulating HBV expression Grant 9,145,558 - Prakash , et al. September 29, 2 | 2015-09-29 |
Oligomeric Compounds Comprising Bicyclic Nucleosides And Uses Thereof App 20150267195 - Seth; Punit P. ;   et al. | 2015-09-24 |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs Grant 9,139,832 - Lollo , et al. September 22, 2 | 2015-09-22 |
Compositions For Modulating C9orf72 Expression App 20150259679 - Bennett; C. Frank ;   et al. | 2015-09-17 |
Oligomeric Compounds Comprising Tricyclic Nucelosides And Methods For Their Use App 20150259681 - Swayze; Eric E. ;   et al. | 2015-09-17 |
Conjugated antisense compounds and their use Grant 9,127,276 - Prakash , et al. September 8, 2 | 2015-09-08 |
Oligomeric compounds and compositions for the use in modulation of target nucleic acids Grant 9,127,272 - Esau , et al. September 8, 2 | 2015-09-08 |
5' modified nucleosides and oligomeric compounds prepared therefrom Grant 9,127,033 - Prakash , et al. September 8, 2 | 2015-09-08 |
Antisense Compounds Having Enhanced Anti-microrna Activity App 20150247142 - Esau; Christine ;   et al. | 2015-09-03 |
2' and 5' modified monomers and oligonucleotides Grant 9,102,938 - Rajeev , et al. August 11, 2 | 2015-08-11 |
Bicyclic Cyclohexose Nucleic Acid Analogs App 20150191727 - Migawa; Michael T. ;   et al. | 2015-07-09 |
Oligomeric Compounds Comprising Bicyclic Nucleotides And Uses Thereof App 20150184153 - Freier; Susan M. ;   et al. | 2015-07-02 |
Compositions And Methods For Modulating Hbv Expression App 20150176007 - Prakash; Thazha P. ;   et al. | 2015-06-25 |
Oligomeric Compounds And Methods App 20150167006 - Swayze; Eric E. ;   et al. | 2015-06-18 |
Modified Nucleosides, Analogs Thereof And Oligomeric Compounds Prepared Therefrom App 20150159163 - Prakash; Thazha P. ;   et al. | 2015-06-11 |
Short antisense compounds with gapmer configuration Grant 9,045,754 - Bhanot , et al. June 2, 2 | 2015-06-02 |
Oligomeric Compounds Comprising Bicyclic Nucleosides And Having Reduced Toxicity App 20150141636 - Swayze; Eric E. ;   et al. | 2015-05-21 |
Modulation of hepatitis B virus (HBV) expression Grant 9,034,841 - Swayze , et al. May 19, 2 | 2015-05-19 |
Substituted 2'-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom Grant 9,029,335 - Prakash , et al. May 12, 2 | 2015-05-12 |
5' And 2' Bis-substituted Nucleosides And Oligomeric Compounds Prepared Therefrom App 20150126725 - Swayze; Eric E. ;   et al. | 2015-05-07 |
Conjugated Antisense Compounds And Their Use App 20150126718 - Prakash; Thazha P. ;   et al. | 2015-05-07 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION App 20150126720 - Prakash; Thazha P. ;   et al. | 2015-05-07 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression App 20150126719 - Prakash; Thazha P. ;   et al. | 2015-05-07 |
Tricyclic Nucleic Acid Analogs App 20150112055 - Seth; Punit P. ;   et al. | 2015-04-23 |
Bicyclic cyclohexose nucleic acid analogs Grant 9,012,421 - Migawa , et al. April 21, 2 | 2015-04-21 |
Selective reduction of allelic variants Grant 9,006,198 - Bennett , et al. April 14, 2 | 2015-04-14 |
Tetrahydropyran nucleic acid analogs Grant 9,005,906 - Swayze , et al. April 14, 2 | 2015-04-14 |
Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom Grant 8,993,738 - Prakash , et al. March 31, 2 | 2015-03-31 |
Oligomeric compounds comprising tricyclic nucelosides and methods for their use Grant 8,993,528 - Swayze , et al. March 31, 2 | 2015-03-31 |
Oligomeric compounds and methods Grant 8,987,435 - Swayze , et al. March 24, 2 | 2015-03-24 |
Compounds and methods for modulating expression of DGAT2 Grant 8,969,316 - Bhanot , et al. March 3, 2 | 2015-03-03 |
Compounds And Methods For Modulating Expression Apob App 20150057329 - BHANOT; Sanjay ;   et al. | 2015-02-26 |
Selective Antisense Compounds And Uses Thereof App 20150051389 - Seth; Punit P. ;   et al. | 2015-02-19 |
Selective reduction of allelic variants Grant 8,957,040 - Bennett , et al. February 17, 2 | 2015-02-17 |
Bicyclic nucleosides and oligomeric compounds prepared therefrom Grant 8,957,200 - Seth , et al. February 17, 2 | 2015-02-17 |
Methods And Compositions For Modulating Factor Vii Expression App 20150031747 - Swayze; Eric E. ;   et al. | 2015-01-29 |
Oligomer-conjugate Complexes And Their Use App 20150018540 - Prakash; Thazha P. ;   et al. | 2015-01-15 |
Compositions And Methods For Optimizing Cleavage Of Rna By Rnase H App 20150011001 - Migawa; Michael T. ;   et al. | 2015-01-08 |
Modulation Of Hepatitis B Virus (hbv) Expression App 20140357701 - Swayze; Eric E. ;   et al. | 2014-12-04 |
Conjugated Antisense Compounds And Their Use App 20140343123 - Prakash; Thazha P. ;   et al. | 2014-11-20 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas App 20140336370 - Esau; Christine ;   et al. | 2014-11-13 |
Modulation Of Signal Transducer And Activator Of Transcription 3 (stat3) Expression App 20140336237 - Swayze; Eric E. ;   et al. | 2014-11-13 |
5' and 2' BIS-substituted nucleosides and oligomeric compounds prepared therefrom Grant 8,883,752 - Swayze , et al. November 11, 2 | 2014-11-11 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas App 20140329882 - Esau; Christine ;   et al. | 2014-11-06 |
Selective Antisense Compounds And Uses Thereof App 20140323707 - Seth; Punit P. ;   et al. | 2014-10-30 |
Methods And Compounds Useful In Conditions Related To Repeat Expansion App 20140316121 - Prakash; Thazha P. ;   et al. | 2014-10-23 |
Tetrahydropyran Nucleic Acid Analogs App 20140315979 - Swayze; Eric E. ;   et al. | 2014-10-23 |
Gapped Oligomeric Compounds Comprising 5'-modified Deoxyribonucleosides In The Gap And Uses Thereof App 20140309279 - Oestergaard; Michael ;   et al. | 2014-10-16 |
Linkage Modified Gapped Oligomeric Compounds And Uses Thereof App 20140303235 - Oestergaard; Michael ;   et al. | 2014-10-09 |
Substituted 2'-amino and 2'-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom Grant 8,846,637 - Seth , et al. September 30, 2 | 2014-09-30 |
Oligomeric compounds comprising bicyclic nucleosides and having reduced toxicity Grant 8,846,639 - Swayze , et al. September 30, 2 | 2014-09-30 |
Modulation of signal transducer and activator of transcription 3 (STAT3)expression Grant 8,816,056 - Swayze , et al. August 26, 2 | 2014-08-26 |
Method of inhibiting miR-33 using a modified oligonucleotide Grant 8,809,294 - Esau , et al. August 19, 2 | 2014-08-19 |
Tetrahydropyran nucleic acid analogs Grant 8,796,437 - Swayze , et al. August 5, 2 | 2014-08-05 |
Compositions and methods for optimizing cleavage of RNA by RNase H Grant 8,790,919 - Migawa , et al. July 29, 2 | 2014-07-29 |
Base modified bicyclic nucleosides and oligomeric compounds prepared therefrom Grant 8,779,118 - Allerson , et al. July 15, 2 | 2014-07-15 |
Antibacterial 4,6-substituted 6', 6'' and 1 modified aminoglycoside analogs Grant 8,742,078 - Migawa , et al. June 3, 2 | 2014-06-03 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas App 20140121364 - Esau; Christine ;   et al. | 2014-05-01 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas App 20140121365 - Esau; Christine ;   et al. | 2014-05-01 |
Gapped oligomeric compounds having linked bicyclic sugar moieties at the termini Grant 8,703,728 - Swayze , et al. April 22, 2 | 2014-04-22 |
Modulation Of Hepatitis B Virus (hbv) Expression App 20140107184 - Swayze; Eric E. ;   et al. | 2014-04-17 |
Substituted 2'-thio-bicyclic Nucleosides And Oligomeric Compounds Prepared Therefrom App 20140106451 - Prakash; Thazha P. ;   et al. | 2014-04-17 |
Oligomeric Compounds Comprising Bicyclic Nucleotides And Uses Thereof App 20140107330 - Freier; Susan M. ;   et al. | 2014-04-17 |
Compounds and methods for modulating expression ApoB Grant 8,673,871 - Bhanot , et al. March 18, 2 | 2014-03-18 |
Cyclohexenyl Nucleic Acids Analogs App 20140073786 - Seth; Punit P. ;   et al. | 2014-03-13 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas App 20140057963 - Esau; Christine ;   et al. | 2014-02-27 |
Modulation of Hepatitis B virus (HBV) expression Grant 8,642,752 - Swayze , et al. February 4, 2 | 2014-02-04 |
Cyclohexenyl nucleic acids analogs Grant 8,604,192 - Seth , et al. December 10, 2 | 2013-12-10 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 8,604,183 - Allerson , et al. December 10, 2 | 2013-12-10 |
5'-end Derivatives App 20130323836 - Manoharan; Muthiah ;   et al. | 2013-12-05 |
Compounds and methods for modulating expression of PTP1B Grant 8,586,554 - Bhanot , et al. November 19, 2 | 2013-11-19 |
Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents Grant 8,569,264 - Swayze , et al. October 29, 2 | 2013-10-29 |
Conformationally Restricted Dinucleotide Monomers And Oligonucleotides App 20130260460 - Lackey; Jeremy ;   et al. | 2013-10-03 |
Carbocyclic alpha-L-bicyclic nucleic acid analogs Grant 8,546,556 - Seth , et al. October 1, 2 | 2013-10-01 |
Tetrahydropyran nucleic acid analogs Grant 8,536,320 - Prakash , et al. September 17, 2 | 2013-09-17 |
Bicyclic cyclohexitol nucleic acid analogs Grant 8,530,640 - Seth , et al. September 10, 2 | 2013-09-10 |
Tetrahydropyran Nucleic Acid Analogs App 20130211064 - Swayze; Eric E. ;   et al. | 2013-08-15 |
2' And 5' Modified Monomers And Oligonucleotides App 20130203836 - Rajeev; Kallanthottathil G. ;   et al. | 2013-08-08 |
Substituted alpha-L-bicyclic nucleosides Grant 8,501,805 - Seth , et al. August 6, 2 | 2013-08-06 |
Oligomeric Compounds Comprising Tricyclic Nucelosides And Methods For Their Use App 20130197062 - Swayze; Eric E. ;   et al. | 2013-08-01 |
Modulation Of Eif4e Expression App 20130178513 - Dobie; Kenneth W. ;   et al. | 2013-07-11 |
Compounds And Methods For Modulating Expression Of Gccr App 20130165496 - Bhanot; Sanjay ;   et al. | 2013-06-27 |
Lipid Formulated Single Stranded Rna App 20130156845 - Manoharan; Muthiah ;   et al. | 2013-06-20 |
Bicyclic Nucleosides And Oligomeric Compounds Prepared Therefrom App 20130150569 - Seth; Punit P. ;   et al. | 2013-06-13 |
Antibacterial 4,6-substituted 6', 6'' And 1 Modified Aminoglycoside Analogs App 20130144044 - Migawa; Michael T. ;   et al. | 2013-06-06 |
Substituted 2'-amino And 2'-thio-bicyclic Nucleosides And Oligomeric Compounds Prepared Therefrom App 20130131147 - Seth; Punit P. ;   et al. | 2013-05-23 |
Tetrahydropyran nucleic acid analogs Grant 8,440,803 - Swayze , et al. May 14, 2 | 2013-05-14 |
5' Modified Nucleosides And Oligomeric Compounds Prepared Therefrom App 20130116420 - Prakash; Thazha P. ;   et al. | 2013-05-09 |
Modified 5' Diphosphate Nucleosides And Oligomeric Compounds Prepared Therefrom App 20130109850 - Prakash; Thazha P. ;   et al. | 2013-05-02 |
Oligomeric compounds comprising tricyclic nucelosides and methods for their use Grant 8,426,378 - Swayze , et al. April 23, 2 | 2013-04-23 |
Modified Nucleosides, Analogs Thereof And Oligomeric Compounds Prepared Therefrom App 20130084576 - Prakash; Thazha P. ;   et al. | 2013-04-04 |
Modulation of eIF4E expression Grant 8,410,074 - Dobie , et al. April 2, 2 | 2013-04-02 |
Positionally modified siRNA constructs Grant 8,394,947 - Bhat , et al. March 12, 2 | 2013-03-12 |
Methods And Compositions Useful In Treatment Of Diseases Or Conditions Related To Repeat Expansion App 20130059902 - Corey; David ;   et al. | 2013-03-07 |
Selective Reduction Of Allelic Variants App 20130046008 - Bennett; C. Frank ;   et al. | 2013-02-21 |
Selective Reduction Of Allelic Variants App 20130046007 - Bennett; C. Frank ;   et al. | 2013-02-21 |
Antibacterial 4,6-substituted 6', 6'' and 1 modified aminoglycoside analogs Grant 8,377,896 - Migawa , et al. February 19, 2 | 2013-02-19 |
Compounds and methods for modulating expression of GCCR Grant 8,372,967 - Bhanot , et al. February 12, 2 | 2013-02-12 |
Compounds and methods for modulating expression of SGLT2 Grant 8,362,232 - Bhanot , et al. January 29, 2 | 2013-01-29 |
Carbocyclic bicyclic nucleic acid analogs Grant 8,278,426 - Seth , et al. October 2, 2 | 2012-10-02 |
N-substituted-aminomethylene bridged bicyclic nucleic acid analogs Grant 8,278,425 - Prakash , et al. October 2, 2 | 2012-10-02 |
6-disubstituted or unsaturated bicyclic nucleic acid analogs Grant 8,278,283 - Seth , et al. October 2, 2 | 2012-10-02 |
5'-modified bicyclic nucleic acid analogs Grant 8,268,980 - Seth , et al. September 18, 2 | 2012-09-18 |
Benzimidazoles and analogs thereof as antivirals Grant 8,207,173 - Seth , et al. June 26, 2 | 2012-06-26 |
Compounds and methods for modulating expression of GCGR Grant 8,188,059 - Bhanot , et al. May 29, 2 | 2012-05-29 |
Oligomeric compounds and compositions for the use in modulation of microRNAs Grant 8,129,515 - Esau , et al. March 6, 2 | 2012-03-06 |
Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation Grant 8,124,745 - Allerson , et al. February 28, 2 | 2012-02-28 |
Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents Grant 8,114,856 - Swayze , et al. February 14, 2 | 2012-02-14 |
Bis-modified bicyclic nucleic acid analogs Grant 8,088,746 - Seth , et al. January 3, 2 | 2012-01-03 |
Tetrahydropyran nucleic acid analogs Grant 8,088,904 - Swayze , et al. January 3, 2 | 2012-01-03 |
5'-modified bicyclic nucleic acid analogs Grant 8,030,467 - Seth , et al. October 4, 2 | 2011-10-04 |
6-modified bicyclic nucleic acid analogs Grant 8,022,193 - Seth , et al. September 20, 2 | 2011-09-20 |
Oligomeric compounds comprising 4'-thionucleosides for use in gene modulation Grant 7,939,677 - Bhat , et al. May 10, 2 | 2011-05-10 |
2'-substituted oligomeric compounds and compositions for use in gene modulations Grant 7,919,612 - Baker , et al. April 5, 2 | 2011-04-05 |
Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents Grant 7,893,039 - Swayze , et al. February 22, 2 | 2011-02-22 |
Oligomeric compounds comprising 4'-thionucleosides for use in gene modulation Grant 7,875,733 - Bhat , et al. January 25, 2 | 2011-01-25 |
Carbocyclic Alpha-l-bicyclic Nucleic Acid Analogs App 20100331538A1 - | 2010-12-30 |
2'-Fluoro substituted oligomeric compounds and compositions for use in gene modulations Grant 7,812,149 - Prakash , et al. October 12, 2 | 2010-10-12 |
Double stranded compositions comprising a 3'-endo modified strand for use in gene modulation Grant 7,790,691 - Kraynack , et al. September 7, 2 | 2010-09-07 |
5'-modified bicyclic nucleic acid analogs Grant 7,750,131 - Seth , et al. July 6, 2 | 2010-07-06 |
6-modified bicyclic nucleic acid analogs Grant 7,741,457 - Seth , et al. June 22, 2 | 2010-06-22 |
Oligomers comprising activated disulfides which bind to plasma proteins and their use for delivery to cells Grant 7,713,944 - Kinberger , et al. May 11, 2 | 2010-05-11 |
Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation Grant 7,696,345 - Allerson , et al. April 13, 2 | 2010-04-13 |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs Grant 7,683,036 - Esau , et al. March 23, 2 | 2010-03-23 |
Bis-modified bicyclic nucleic acid analogs Grant 7,666,854 - Seth , et al. February 23, 2 | 2010-02-23 |
Benzimidazoles and analogs thereof as antivirals Grant 7,642,265 - Seth , et al. January 5, 2 | 2010-01-05 |
Modulation of eIF4E expression Grant 7,601,700 - Dobie , et al. October 13, 2 | 2009-10-13 |
Compounds and methods for synthesis of bicyclic nucleic acid analogs Grant 7,569,686 - Bhat , et al. August 4, 2 | 2009-08-04 |
5'-modified bicyclic nucleic acid analogs Grant 7,547,684 - Seth , et al. June 16, 2 | 2009-06-16 |