| Patent | Date |
|---|
Compositions and methods for modulating angiopoietin-like 3 expression
Grant 10,875,884 - Prakash , et al. December 29, 2 | 2020-12-29 |
5' modified nucleosides and oligomeric compounds prepared therefrom
Grant 10,676,738 - Prakash , et al. | 2020-06-09 |
Methods For Modulating Tau Expression For Reducing Seizure And Modifying A Neurodegenerative Syndrome
App 20200032257 - Miller; Timothy M. ; et al. | 2020-01-30 |
Modulation of signal transducer and activator of transcription 3 (STAT3) expression
Grant 10,479,993 - Swayze , et al. Nov | 2019-11-19 |
Methods for modulating Tau expression for reducing seizure and modifying a neurodegenerative syndrome
Grant 10,273,474 - Miller , et al. | 2019-04-30 |
Compounds and methods for modulating apolipoprotein C-III expression for improving a diabetic profile
Grant 9,909,124 - Crooke , et al. March 6, 2 | 2018-03-06 |
Modulation of dystrophia myotonica-protein kinase (DMPK) expression
Grant 9,765,338 - Bennett , et al. September 19, 2 | 2017-09-19 |
Antisense compounds and uses thereof
Grant 9,714,288 - Oestergaard , et al. July 25, 2 | 2017-07-25 |
Methods for treating hypercholesterolemia
Grant 9,650,636 - Freier , et al. May 16, 2 | 2017-05-16 |
Modulation Of Signal Transducer And Activator Of Transcription 3 (stat3) Expression
App 20160348104 - Swayze; Eric E. ; et al. | 2016-12-01 |
Method of preparing oligomeric compounds using modified capping protocols
Grant 9,403,865 - Cedillo , et al. August 2, 2 | 2016-08-02 |
Compositions and methods for modulating angiopoietin-like 3 expression
Grant 9,382,540 - Prakash , et al. July 5, 2 | 2016-07-05 |
Methods And Compounds Useful In Conditions Related To Repeat Expansion
App 20160159846 - Prakash; Thazha P. ; et al. | 2016-06-09 |
Methods Of Predicting Toxicity
App 20160160280 - Burel; Sebastian | 2016-06-09 |
Modulation of signal transducer and activator of transcription 3 (STAT3) expression
Grant 9,359,608 - Swayze , et al. June 7, 2 | 2016-06-07 |
Compounds And Methods For Modulating Apolipoprotein C-iii Expression For Improving A Diabetic Profile
App 20160152974 - M.Crooke; Rosanne M. ; et al. | 2016-06-02 |
Compositions For Modulating Tau Expression
App 20160145617 - Kordasiewicz; Holly ; et al. | 2016-05-26 |
Antisense Compounds And Uses Thereof
App 20160138014 - Kordasiewicz; Holly ; et al. | 2016-05-19 |
Compositions And Methods For Modulation Of Target Nucleic Acids
App 20160122761 - Prakash; Thazha P. ; et al. | 2016-05-05 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION
App 20160090596 - Prakash; Thazha P. ; et al. | 2016-03-31 |
Antisense Compounds And Uses Thereof
App 20160090598 - Oestergaard; Michael ; et al. | 2016-03-31 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression
App 20160090595 - Prakash; Thazha P. ; et al. | 2016-03-31 |
Compositions And Methods For Modulating Hbv Expression
App 20160076030 - Prakash; Thazha P. ; et al. | 2016-03-17 |
Compositions And Methods
App 20160076032 - Prakash; Thazha P. ; et al. | 2016-03-17 |
Compositions And Methods For Modulation Nucleic Acids Through Nonsense Mediated Decay
App 20160076027 - WARD; Amanda ; et al. | 2016-03-17 |
Phosphorous-linked Oligomeric Compounds And Their Use In Gene Modulation
App 20160076031 - Baker; Brenda F. ; et al. | 2016-03-17 |
Modulation Of Androgen Receptor Expression
App 20160068846 - Macleod; Robert A. ; et al. | 2016-03-10 |
Modulation Of Dystrophia Myotonica-protein Kinase (dmpk) Expression
App 20160068845 - Bennett; C. Frank ; et al. | 2016-03-10 |
Modulation Of Apolipoprotein Ciii (apociii) Expression
App 20160060625 - Mullick; Adam ; et al. | 2016-03-03 |
Modulation Of Angiopoietin-like 3 Expression
App 20160060626 - Crooke; Rosanne M. ; et al. | 2016-03-03 |
Modulation of huntingtin expression
Grant 9,273,315 - Hung , et al. March 1, 2 | 2016-03-01 |
Compositions And Their Uses Directed To Huntingtin
App 20160053256 - Hung; Gene ; et al. | 2016-02-25 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation
App 20160053261 - Allerson; Charles ; et al. | 2016-02-25 |
5' Modified Nucleosides And Oligomeric Compounds Prepared Therefrom
App 20160046939 - Prakash; Thazha P. ; et al. | 2016-02-18 |
Modulation Of Hepatitis B Virus (hbv) Expression
App 20160046945 - Swayze; Eric E. ; et al. | 2016-02-18 |
Compositions And Methods For Modulating Tau Expression
App 20160032285 - Rigo; Frank ; et al. | 2016-02-04 |
Methods For Monitoring C9orf72 Expression
App 20160024496 - Bennett; C. Frank ; et al. | 2016-01-28 |
Methods of predicting toxicity
Grant 9,243,291 - Burel January 26, 2 | 2016-01-26 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation
App 20160017328 - Bhat; Balkrishen ; et al. | 2016-01-21 |
Chimeric Oligomeric Compounds And Their Use In Gene Modulation
App 20160017324 - Baker; Brenda F. ; et al. | 2016-01-21 |
Conjugated Antisense Compounds And Their Use
App 20160017323 - Prakash; Thazha P. ; et al. | 2016-01-21 |
Oligomeric Compounds And Excipients
App 20160010086 - BENNETT; C. FRANK ; et al. | 2016-01-14 |
Cancer Treatment
App 20160002625 - CROOKE; Stanley T. ; et al. | 2016-01-07 |
Compositions And Methods For Modulation Of Smn2 Splicing In A Subject
App 20160002627 - Bennett; C. Frank ; et al. | 2016-01-07 |
Antisense Oligonucleotide Compositions
App 20160002624 - Dibble; Andrew ; et al. | 2016-01-07 |
Selective Antisense Compounds And Uses Thereof
App 20150376625 - Oestergaard; Michael ; et al. | 2015-12-31 |
Modulation Of Apolipoprotein C-iii (apociii) Expression In Lipoprotein Lipase Deficient (lpld) Populations
App 20150376614 - Alexander; Veronica J. ; et al. | 2015-12-31 |
Antisense Oligonucleotides Directed Against Connective Tissue Growth Factor And Uses Thereof
App 20150376623 - Dean; Nicholas M. ; et al. | 2015-12-31 |
Tricyclic nucleic acid analogs
Grant 9,221,864 - Seth , et al. December 29, 2 | 2015-12-29 |
Method Of Preparing Oligomeric Compounds Using Modified Coupling Protocols
App 20150368288 - Cedillo; Isaiah E. ; et al. | 2015-12-24 |
2'-methoxy Substituted Oligomeric Compounds And Compositions For Use In Gene Modulations
App 20150366894 - Crooke; Stanley T. | 2015-12-24 |
Compositions And Methods For Modulation Of Smn2 Splicing
App 20150353929 - Baker; Brenda F. ; et al. | 2015-12-10 |
Compounds And Methods For Modulating Gene Expression
App 20150344879 - Bhanot; Sanjay ; et al. | 2015-12-03 |
Methods And Compositions For Modulating Apolipoprotein (a) Expression
App 20150337303 - Crooke; Rosanne M. ; et al. | 2015-11-26 |
5'-substituted bicyclic nucleosides and oligomeric compounds prepared therefrom
Grant 9,193,752 - Migawa , et al. November 24, 2 | 2015-11-24 |
Selective Reduction Of Allelic Variants
App 20150329859 - Bennett; C. Frank ; et al. | 2015-11-19 |
Methods for modulating factor 12 expression
Grant 9,187,749 - Bhattacharjee , et al. November 17, 2 | 2015-11-17 |
Compounds And Methods For Improved Cellular Uptake Of Antisense Compounds
App 20150322428 - Koller; Erich ; et al. | 2015-11-12 |
Oligomeric Compounds And Compositions For The Use In Modulation Of Micrornas
App 20150322436 - Esau; Christine ; et al. | 2015-11-12 |
Conjugated antisense compounds and their use
Grant 9,181,549 - Prakash , et al. November 10, 2 | 2015-11-10 |
Compositions and methods for modulating apolipoprotein (a) expression
Grant 9,181,550 - Prakash , et al. November 10, 2 | 2015-11-10 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation
App 20150315579 - Bhat; Balkrishen ; et al. | 2015-11-05 |
Compounds And Methods For Improving Cellular Uptake Of Oligomeric Compounds
App 20150315580 - Koller; Erich ; et al. | 2015-11-05 |
Antisense Modulation Of Ptp1b Expression
App 20150315596 - Bhanot; Sanjay ; et al. | 2015-11-05 |
Compositions And Methods For Modulating Angiopoietin-like 3 Expression
App 20150315594 - Prakash; Thazha P. ; et al. | 2015-11-05 |
Modulation of androgen receptor expression
Grant 9,175,291 - Macleod , et al. November 3, 2 | 2015-11-03 |
Compositions And Their Uses Directed To Huntingtin
App 20150307877 - Freier; Susan M. | 2015-10-29 |
Competitive Modulation Of Micrornas
App 20150299789 - Liang; Xue-hai ; et al. | 2015-10-22 |
Modulation Of Renin-angiotensin System (ras) Related Diseases By Angiotensinogen
App 20150297629 - Mullick; Adam ; et al. | 2015-10-22 |
Compositions and methods for modulating apolipoprotein C-III expression
Grant 9,163,239 - Prakash , et al. October 20, 2 | 2015-10-20 |
Antisense Compounds Targeting Genes Associated With Fibronectin
App 20150291955 - Freier; Susan M. ; et al. | 2015-10-15 |
Selective Reduction Of Allelic Variants
App 20150292015 - Bennett; C. Frank ; et al. | 2015-10-15 |
Modulation Of Cd40 Expression
App 20150291960 - Bennett; C. Frank ; et al. | 2015-10-15 |
Modified 5' diphosphate nucleosides and oligomeric compounds prepared therefrom
Grant 9,156,873 - Prakash , et al. October 13, 2 | 2015-10-13 |
Modulation of apolipoprotein CIII (ApoCIII) expression
Grant 9,157,082 - Mullick , et al. October 13, 2 | 2015-10-13 |
Chimeric oligomeric compounds for modulation of splicing
Grant 9,157,081 - Bennett , et al. October 13, 2 | 2015-10-13 |
Methods Of Treating Kennedy's Disease
App 20150284725 - Hung; Gene | 2015-10-08 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Grant 9,150,605 - Allerson , et al. October 6, 2 | 2015-10-06 |
Methods for modulating factor 12 expression
Grant 9,150,864 - Monia , et al. October 6, 2 | 2015-10-06 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Grant 9,150,606 - Allerson , et al. October 6, 2 | 2015-10-06 |
Selective Antisense Compounds And Uses Thereof
App 20150275208 - Oestergaard; Michael ; et al. | 2015-10-01 |
Antisense Compounds And Uses Thereof
App 20150275211 - Rigo; Frank ; et al. | 2015-10-01 |
Methods For Modulating Tau Expression For Reducing Seizure And Modifying A Neurodegenerative Syndrome
App 20150275205 - Miller; Timothy M. ; et al. | 2015-10-01 |
Compositions and methods for modulating HBV expression
Grant 9,145,558 - Prakash , et al. September 29, 2 | 2015-09-29 |
Oligomeric Compounds Comprising Bicyclic Nucleosides And Uses Thereof
App 20150267195 - Seth; Punit P. ; et al. | 2015-09-24 |
Methods For Modulating C9orf72 Expression
App 20150267197 - Bennett; C. Frank ; et al. | 2015-09-24 |
Modulation of angiopoietin-like 3 expression
Grant 9,139,831 - Crooke , et al. September 22, 2 | 2015-09-22 |
Compositions For Modulating C9orf72 Expression
App 20150259679 - Bennett; C. Frank ; et al. | 2015-09-17 |
Oligomeric Compounds Comprising Tricyclic Nucelosides And Methods For Their Use
App 20150259681 - Swayze; Eric E. ; et al. | 2015-09-17 |
Modulation Of Transthyretin Expression
App 20150252367 - Monia; Brett P. ; et al. | 2015-09-10 |
Conjugated antisense compounds and their use
Grant 9,127,276 - Prakash , et al. September 8, 2 | 2015-09-08 |
5' modified nucleosides and oligomeric compounds prepared therefrom
Grant 9,127,033 - Prakash , et al. September 8, 2 | 2015-09-08 |
Modulation of hepatitis B virus (HBV) expression
Grant 9,127,278 - Freier September 8, 2 | 2015-09-08 |
Oligomeric compounds and compositions for the use in modulation of target nucleic acids
Grant 9,127,272 - Esau , et al. September 8, 2 | 2015-09-08 |
Compositions and methods of targeting apolipoprotein B for the reduction of apolipoprotein C-III
Grant 9,107,933 - Sacks , et al. August 18, 2 | 2015-08-18 |
Method Of Preparing Oligomeric Compounds Using Modified Capping Protocols
App 20150218205 - Cedillo; Isaiah E. ; et al. | 2015-08-06 |
Chimeric oligomeric compounds and their use in gene modulation
Grant 9,096,636 - Crooke August 4, 2 | 2015-08-04 |
Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
Grant 9,096,851 - Dean , et al. August 4, 2 | 2015-08-04 |
Modulation Of Ube3a-ats Expression
App 20150191723 - Rigo; Frank ; et al. | 2015-07-09 |
Bicyclic Cyclohexose Nucleic Acid Analogs
App 20150191727 - Migawa; Michael T. ; et al. | 2015-07-09 |
MODULATION OF APOLIPOPROTEIN (a) EXPRESSION
App 20150184156 - Crooke; Rosanne M. ; et al. | 2015-07-02 |
Modulation Of Transthyretin Expression
App 20150184157 - Brown-Driver; Vickie L. ; et al. | 2015-07-02 |
Antisense Modulation Of Fibroblast Growth Factor Receptor 4 Expression
App 20150184164 - Bhanot; Sanjay ; et al. | 2015-07-02 |
Oligomeric Compounds Comprising Bicyclic Nucleotides And Uses Thereof
App 20150184153 - Freier; Susan M. ; et al. | 2015-07-02 |
Modulation Of Enhancer Rna Mediated Gene Expression
App 20150176005 - Freier; Susan M. ; et al. | 2015-06-25 |
Compositions And Methods For Modulating Hbv Expression
App 20150176007 - Prakash; Thazha P. ; et al. | 2015-06-25 |
Modulation of transthyretin expression
Grant 9,061,044 - Freier June 23, 2 | 2015-06-23 |
Methods For Treating Hypercholesterolemia
App 20150167005 - Freier; Susan M. ; et al. | 2015-06-18 |
Antisense Modulation Of Superoxide Dismutase 1, Soluble Expression
App 20150167008 - Bennett; C. Frank ; et al. | 2015-06-18 |
Oligomeric Compounds And Methods
App 20150167006 - Swayze; Eric E. ; et al. | 2015-06-18 |
Compositions and their uses directed to huntingtin
Grant 9,057,066 - Hung , et al. June 16, 2 | 2015-06-16 |
Modulation Of Huntingtin Expression
App 20150159155 - Hung; Gene ; et al. | 2015-06-11 |
Modified Nucleosides, Analogs Thereof And Oligomeric Compounds Prepared Therefrom
App 20150159163 - Prakash; Thazha P. ; et al. | 2015-06-11 |
Methods And Compositions For Modulating Apolipoprotein (a) Expression
App 20150152411 - Crooke; Rosanne M. ; et al. | 2015-06-04 |
Short antisense compounds with gapmer configuration
Grant 9,045,754 - Bhanot , et al. June 2, 2 | 2015-06-02 |
Antisense Modulation Of Gccr Expression
App 20150141493 - Freier; Susan M. ; et al. | 2015-05-21 |
Oligomeric Compounds Comprising Bicyclic Nucleosides And Having Reduced Toxicity
App 20150141636 - Swayze; Eric E. ; et al. | 2015-05-21 |
Antisense modulation of PTP1B expression
Grant 9,034,842 - Bhanot , et al. May 19, 2 | 2015-05-19 |
Modulation of hepatitis B virus (HBV) expression
Grant 9,034,841 - Swayze , et al. May 19, 2 | 2015-05-19 |
Apparatus for synthesizing oligonucleotides and methods of use
Grant 9,034,272 - Cedillo , et al. May 19, 2 | 2015-05-19 |
Substituted 2'-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom
Grant 9,029,335 - Prakash , et al. May 12, 2 | 2015-05-12 |
Modulation of factor 7 expression
Grant 9,029,337 - Freier , et al. May 12, 2 | 2015-05-12 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION
App 20150126720 - Prakash; Thazha P. ; et al. | 2015-05-07 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression
App 20150126719 - Prakash; Thazha P. ; et al. | 2015-05-07 |
Conjugated Antisense Compounds And Their Use
App 20150126718 - Prakash; Thazha P. ; et al. | 2015-05-07 |
5' And 2' Bis-substituted Nucleosides And Oligomeric Compounds Prepared Therefrom
App 20150126725 - Swayze; Eric E. ; et al. | 2015-05-07 |
Tricyclic Nucleic Acid Analogs
App 20150112055 - Seth; Punit P. ; et al. | 2015-04-23 |
Bicyclic cyclohexose nucleic acid analogs
Grant 9,012,421 - Migawa , et al. April 21, 2 | 2015-04-21 |
Antisense Compounds Targeting Genes Associated With Fibronectin
App 20150105444 - Freier; Susan M. ; et al. | 2015-04-16 |
Tetrahydropyran nucleic acid analogs
Grant 9,005,906 - Swayze , et al. April 14, 2 | 2015-04-14 |
Selective reduction of allelic variants
Grant 9,006,198 - Bennett , et al. April 14, 2 | 2015-04-14 |
Antisense Modulation Of Gcgr Expression
App 20150099792 - Freier; Susan M. ; et al. | 2015-04-09 |
Compounds and methods for improving cellular uptake of oligomeric compounds
Grant 8,999,951 - Koller , et al. April 7, 2 | 2015-04-07 |
Oligomeric compounds comprising tricyclic nucelosides and methods for their use
Grant 8,993,528 - Swayze , et al. March 31, 2 | 2015-03-31 |
Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom
Grant 8,993,738 - Prakash , et al. March 31, 2 | 2015-03-31 |
Antisense modulation of superoxide dismutase 1, soluble expression
Grant 8,993,529 - Bennett , et al. March 31, 2 | 2015-03-31 |
Methods And Compositions For Modulating Alpha-1-antitrypsin Expression
App 20150087691 - Monia; Brett P. ; et al. | 2015-03-26 |
Oligomeric compounds and methods
Grant 8,987,435 - Swayze , et al. March 24, 2 | 2015-03-24 |
Compositions and methods for modulation of SMN2 splicing in a subject
Grant 8,980,853 - Bennett , et al. March 17, 2 | 2015-03-17 |
Compounds and methods for modulating expression of DGAT2
Grant 8,969,316 - Bhanot , et al. March 3, 2 | 2015-03-03 |
Compounds And Methods For Modulating Expression Apob
App 20150057329 - BHANOT; Sanjay ; et al. | 2015-02-26 |
Selective Antisense Compounds And Uses Thereof
App 20150051389 - Seth; Punit P. ; et al. | 2015-02-19 |
Bicyclic nucleosides and oligomeric compounds prepared therefrom
Grant 8,957,200 - Seth , et al. February 17, 2 | 2015-02-17 |
Selective reduction of allelic variants
Grant 8,957,040 - Bennett , et al. February 17, 2 | 2015-02-17 |
Compositions and their uses directed to huntingtin
Grant 8,952,145 - Freier February 10, 2 | 2015-02-10 |
Method for reducing scarring during wound healing using antisense compounds directed to CTGF
Grant 8,946,172 - Mustoe , et al. February 3, 2 | 2015-02-03 |
Compositions and methods for modulation of SMN2 splicing
Grant 8,946,183 - Baker , et al. February 3, 2 | 2015-02-03 |
Compositions and methods for treatment of pouchitis
Grant 8,946,178 - Wedel , et al. February 3, 2 | 2015-02-03 |
Methods And Compositions For Modulating Factor Vii Expression
App 20150031747 - Swayze; Eric E. ; et al. | 2015-01-29 |
Compositions And Methods For Modulation Of Ikbkap Splicing
App 20150025231 - Bennett; C. Frank ; et al. | 2015-01-22 |
Oligomer-conjugate Complexes And Their Use
App 20150018540 - Prakash; Thazha P. ; et al. | 2015-01-15 |
Antisense modulation of fibroblast growth factor receptor 4 expression
Grant 8,933,213 - Bhanot , et al. January 13, 2 | 2015-01-13 |
Compositions And Methods For Optimizing Cleavage Of Rna By Rnase H
App 20150011001 - Migawa; Michael T. ; et al. | 2015-01-08 |
Methods for slowing familial ALS disease progression
Grant 8,921,331 - Bennett , et al. December 30, 2 | 2014-12-30 |
Methods for slowing familial ALS disease progression
Grant 08921331 - | 2014-12-30 |
Modulation Of Rna By Repeat Targeting
App 20140378533 - Freier; Susan M. | 2014-12-25 |
Modulation of CD40 expression
Grant 8,916,531 - Bennett , et al. December 23, 2 | 2014-12-23 |
Methods For Modulating Metastasis-associated-in-lung-adenocarcinoma-transcript-1 (malat-1) Expression
App 20140371296 - Bennett; C. Frank ; et al. | 2014-12-18 |
Methods for treating hypercholesterolemia
Grant 8,912,160 - Freier , et al. December 16, 2 | 2014-12-16 |
Modulation of huntingtin expression
Grant 8,906,873 - Hung , et al. December 9, 2 | 2014-12-09 |
Chimeric Oligomeric Compounds Comprising Alternating Regions Of Northern And Southern Conformational Geometry
App 20140357856 - Monia; Brett P. ; et al. | 2014-12-04 |
Modulation Of Hepatitis B Virus (hbv) Expression
App 20140357701 - Swayze; Eric E. ; et al. | 2014-12-04 |
Antisense modulation of GCCR expression
Grant 8,901,098 - Freier , et al. December 2, 2 | 2014-12-02 |
Antisense modulation of fibroblast growth factor receptor 4 expression
Grant 8,895,529 - Bhanot , et al. November 25, 2 | 2014-11-25 |
Conjugated Antisense Compounds And Their Use
App 20140343123 - Prakash; Thazha P. ; et al. | 2014-11-20 |
Modulation Of Signal Transducer And Activator Of Transcription 3 (stat3) Expression
App 20140336237 - Swayze; Eric E. ; et al. | 2014-11-13 |
Modulation of diacylglycerol acyltransferase 2 expression
Grant 8,883,997 - Bhanot , et al. November 11, 2 | 2014-11-11 |
5' and 2' BIS-substituted nucleosides and oligomeric compounds prepared therefrom
Grant 8,883,752 - Swayze , et al. November 11, 2 | 2014-11-11 |
Selective Antisense Compounds And Uses Thereof
App 20140323707 - Seth; Punit P. ; et al. | 2014-10-30 |
Tetrahydropyran Nucleic Acid Analogs
App 20140315979 - Swayze; Eric E. ; et al. | 2014-10-23 |
Antisense modulation of GCGR expression
Grant 8,865,674 - Freier , et al. October 21, 2 | 2014-10-21 |
Antisense modulation of kinesin-like 1 expression
Grant 8,865,884 - Dobie , et al. October 21, 2 | 2014-10-21 |
Compositions And Methods For Modulation Of Lmna Expression
App 20140309282 - Bennett; C. Frank ; et al. | 2014-10-16 |
Modulation Of Tmprss6 Expression
App 20140309286 - Guo; Shuling | 2014-10-16 |
Gapped Oligomeric Compounds Comprising 5'-modified Deoxyribonucleosides In The Gap And Uses Thereof
App 20140309279 - Oestergaard; Michael ; et al. | 2014-10-16 |
Modulation of C-reactive protein expression
Grant 8,859,514 - Crooke , et al. October 14, 2 | 2014-10-14 |
Linkage Modified Gapped Oligomeric Compounds And Uses Thereof
App 20140303235 - Oestergaard; Michael ; et al. | 2014-10-09 |
Antisense modulation of PTP1B expression
Grant 8,853,178 - Bhanot , et al. October 7, 2 | 2014-10-07 |
Substituted 2'-amino and 2'-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom
Grant 8,846,637 - Seth , et al. September 30, 2 | 2014-09-30 |
Compounds And Methods For Modulating Protein Expression
App 20140288291 - Bennett; C. Frank | 2014-09-25 |
Antisense Compounds And Methods Of Use Thereof
App 20140275207 - Pandey; Sanjay K. ; et al. | 2014-09-18 |
Modulation Of Transthyretin Expression
App 20140256797 - Monia; Brett P. ; et al. | 2014-09-11 |
Modulation of signal transducer and activator of transcription 3 (STAT3)expression
Grant 8,816,056 - Swayze , et al. August 26, 2 | 2014-08-26 |
Methods For Modulating Factor 12 Expression
App 20140228300 - Bhattacharjee; Gourab ; et al. | 2014-08-14 |
Tetrahydropyran nucleic acid analogs
Grant 8,796,437 - Swayze , et al. August 5, 2 | 2014-08-05 |
Methods For Modulating Kallikrein (klkb1) Expression
App 20140213631 - Bhattacharjee; Gourab ; et al. | 2014-07-31 |
Chimeric oligomeric compounds comprising alternating regions of northern and southern conformational geometry
Grant 8,791,083 - Monia , et al. July 29, 2 | 2014-07-29 |
Compositions and methods for optimizing cleavage of RNA by RNase H
Grant 8,790,919 - Migawa , et al. July 29, 2 | 2014-07-29 |
Compositions and methods for modulation of LMNA expression
Grant 8,791,088 - Bennett , et al. July 29, 2 | 2014-07-29 |
MODULATION OF APOLIPOPROTEIN (a) EXPRESSION
App 20140206750 - Crooke; Rosanne M. ; et al. | 2014-07-24 |
Methods For Modulating Kallikrein (klkb1) Expression
App 20140206745 - Revenko; Alexey ; et al. | 2014-07-24 |
Base modified bicyclic nucleosides and oligomeric compounds prepared therefrom
Grant 8,779,118 - Allerson , et al. July 15, 2 | 2014-07-15 |
Modulation of eIF4E-BP1 expression
Grant 8,778,900 - Monia , et al. July 15, 2 | 2014-07-15 |
Methods For Treating Hypercholesterolemia
App 20140194492 - Freier; Susan M. ; et al. | 2014-07-10 |
Modulation Of Angiopoietin-like 3 Expression
App 20140193825 - Crooke; Rosanne M. ; et al. | 2014-07-10 |
Methods for inhibiting expression of connective tissue growth factor
Grant 8,772,260 - Dean , et al. July 8, 2 | 2014-07-08 |
Antisense Oligonucleotide Modulation Of Raf Gene Expression
App 20140187601 - Monia; Brett P. | 2014-07-03 |
Modification of MYD88 splicing using modified oligonucleotides
Grant 8,765,703 - Vickers , et al. July 1, 2 | 2014-07-01 |
Antibacterial 4,6-substituted 6', 6'' and 1 modified aminoglycoside analogs
Grant 8,742,078 - Migawa , et al. June 3, 2 | 2014-06-03 |
Modulation of factor 11 expression
Grant 8,735,370 - Freier , et al. May 27, 2 | 2014-05-27 |
Modulation of stat5 expression
Grant 8,722,873 - Freier , et al. May 13, 2 | 2014-05-13 |
Antisense modulation of C-reactive protein expression
Grant 8,710,023 - Crooke , et al. April 29, 2 | 2014-04-29 |
Gapped oligomeric compounds having linked bicyclic sugar moieties at the termini
Grant 8,703,728 - Swayze , et al. April 22, 2 | 2014-04-22 |
Diagnosis and treatment of disease
Grant 8,697,860 - Monia , et al. April 15, 2 | 2014-04-15 |
Compositions and methods for non-parenteral delivery of oligonucleotides
Grant 8,691,785 - Teng , et al. April 8, 2 | 2014-04-08 |
Compounds and methods for modulating expression ApoB
Grant 8,673,871 - Bhanot , et al. March 18, 2 | 2014-03-18 |
Modulation of apolipoprotein (a) expression
Grant 8,673,632 - Crooke , et al. March 18, 2 | 2014-03-18 |
Modulation of prion expression
Grant 8,669,102 - Bennett , et al. March 11, 2 | 2014-03-11 |
Methods for treating hypercholesterolemia
Grant 8,664,190 - Freier , et al. March 4, 2 | 2014-03-04 |
Antisense modulation of PTP1B expression
Grant 8,658,783 - Bhanot , et al. February 25, 2 | 2014-02-25 |
Modulation of angiopoietin-like 3 expression
Grant 8,653,047 - Crooke , et al. February 18, 2 | 2014-02-18 |
2-aminopyridine and 2-pyridone C-nucleosides
Grant 8,653,248 - Froehler , et al. February 18, 2 | 2014-02-18 |
Modulation of glucagon receptor expression
Grant 8,642,753 - Freier , et al. February 4, 2 | 2014-02-04 |
Modulation of Hepatitis B virus (HBV) expression
Grant 8,642,752 - Swayze , et al. February 4, 2 | 2014-02-04 |
Compounds and methods for modulating protein expression
Grant 8,637,478 - Bennett January 28, 2 | 2014-01-28 |
Modulation of growth hormone receptor expression and insulin-like growth factor expression
Grant 8,637,484 - Tachas , et al. January 28, 2 | 2014-01-28 |
Antisense oligonucleotide modulation of STAT3 expression
Grant 8,623,643 - Karras January 7, 2 | 2014-01-07 |
Modulation of growth hormone receptor expression and insulin-like growth factor expression
Grant 8,623,836 - Tachas , et al. January 7, 2 | 2014-01-07 |
Modulation of exportin 5 expression
Grant 8,614,310 - Dobie December 24, 2 | 2013-12-24 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Grant 8,604,183 - Allerson , et al. December 10, 2 | 2013-12-10 |
Cyclohexenyl nucleic acids analogs
Grant 8,604,192 - Seth , et al. December 10, 2 | 2013-12-10 |
Compounds and methods for modulating expression of PTP1B
Grant 8,586,554 - Bhanot , et al. November 19, 2 | 2013-11-19 |
Modulation of forkhead box O1A expression
Grant 8,580,948 - Dobie , et al. November 12, 2 | 2013-11-12 |
Double stranded constructs comprising one or more short strands hybridized to a longer strand
Grant 8,569,474 - Baker , et al. October 29, 2 | 2013-10-29 |
Proinflammatory nucleic acids
Grant 8,568,976 - Senn October 29, 2 | 2013-10-29 |
Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
Grant 8,569,264 - Swayze , et al. October 29, 2 | 2013-10-29 |
Carbocyclic alpha-L-bicyclic nucleic acid analogs
Grant 8,546,556 - Seth , et al. October 1, 2 | 2013-10-01 |
Modulation of SMRT expression
Grant 8,541,387 - Pandey , et al. September 24, 2 | 2013-09-24 |
Supports for oligomer synthesis
Grant 8,541,599 - Ravikumar , et al. September 24, 2 | 2013-09-24 |
Methods for modulating expression of RBP4
Grant 8,541,388 - Monia , et al. September 24, 2 | 2013-09-24 |
Tetrahydropyran nucleic acid analogs
Grant 8,536,320 - Prakash , et al. September 17, 2 | 2013-09-17 |
Bicyclic cyclohexitol nucleic acid analogs
Grant 8,530,640 - Seth , et al. September 10, 2 | 2013-09-10 |
Modulation of apolipoprotein C-III expression
Grant 8,530,439 - Crooke , et al. September 10, 2 | 2013-09-10 |
Modulation of STAT 6 expression
Grant 8,518,904 - Shanahan, Jr. , et al. August 27, 2 | 2013-08-27 |
Modulation of HIF1.alpha. and HIF2.alpha. expression
Grant 8,513,400 - Ward , et al. August 20, 2 | 2013-08-20 |
Substituted alpha-L-bicyclic nucleosides
Grant 8,501,805 - Seth , et al. August 6, 2 | 2013-08-06 |
Chimeric oligomeric compounds for modulation of splicing
Grant 8,501,703 - Bennett , et al. August 6, 2 | 2013-08-06 |
Antisense modulation of fibroblast growth factor receptor 4 expression
Grant 8,486,904 - Bhanot , et al. July 16, 2 | 2013-07-16 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
Grant 8,481,712 - Bhat , et al. July 9, 2 | 2013-07-09 |
Antisense modulation of kinesin-like 1 expression
Grant 8,470,795 - Dobie , et al. June 25, 2 | 2013-06-25 |
Compositions and their uses directed to diacylglycerol acyltransferase 1
Grant 8,455,456 - Yu , et al. June 4, 2 | 2013-06-04 |
Tetrahydropyran nucleic acid analogs
Grant 8,440,803 - Swayze , et al. May 14, 2 | 2013-05-14 |
Oligomeric compounds comprising tricyclic nucelosides and methods for their use
Grant 8,426,378 - Swayze , et al. April 23, 2 | 2013-04-23 |
Compositions and their uses directed to huntingtin
Grant 8,415,465 - Freier April 9, 2 | 2013-04-09 |
Compositions and their uses directed to gemin genes
Grant 8,409,856 - Dobie , et al. April 2, 2 | 2013-04-02 |
Modulation of eIF4E expression
Grant 8,410,074 - Dobie , et al. April 2, 2 | 2013-04-02 |
Positionally modified siRNA constructs
Grant 8,394,947 - Bhat , et al. March 12, 2 | 2013-03-12 |
Antidotes to antisense compounds
Grant 8,389,488 - Monia , et al. March 5, 2 | 2013-03-05 |
Compositions and methods for non-parenteral delivery of oligonucleotides
Grant 8,377,897 - Teng , et al. February 19, 2 | 2013-02-19 |
Antibacterial 4,6-substituted 6', 6'' and 1 modified aminoglycoside analogs
Grant 8,377,896 - Migawa , et al. February 19, 2 | 2013-02-19 |
Compounds and methods for modulating expression of GCCR
Grant 8,372,967 - Bhanot , et al. February 12, 2 | 2013-02-12 |
Compounds and methods for modulating expression of SGLT2
Grant 8,362,232 - Bhanot , et al. January 29, 2 | 2013-01-29 |
Compositions and methods for modulation of SMN2 splicing
Grant 8,361,977 - Baker , et al. January 29, 2 | 2013-01-29 |
Methods of determining potency of chemically-synthesized oligonucleotides
Grant 8,338,185 - Lima , et al. December 25, 2 | 2012-12-25 |
Modulation of factor 11 expression
Grant 8,334,372 - Freier , et al. December 18, 2 | 2012-12-18 |
Compounds and methods for improving cellular uptake of oligomeric compounds
Grant 8,318,496 - Koller , et al. November 27, 2 | 2012-11-27 |
Compositions and their uses directed to acetyl-CoA carboxylases
Grant 8,299,041 - Bhanot , et al. October 30, 2 | 2012-10-30 |
Modulation of growth hormone receptor expression and insulin-like growth factor expression
Grant 8,299,039 - Tachas , et al. October 30, 2 | 2012-10-30 |
Carbocyclic bicyclic nucleic acid analogs
Grant 8,278,426 - Seth , et al. October 2, 2 | 2012-10-02 |
N-substituted-aminomethylene bridged bicyclic nucleic acid analogs
Grant 8,278,425 - Prakash , et al. October 2, 2 | 2012-10-02 |
6-disubstituted or unsaturated bicyclic nucleic acid analogs
Grant 8,278,283 - Seth , et al. October 2, 2 | 2012-10-02 |
Combination therapy for the treatment of cancer
Grant 8,268,797 - Graff September 18, 2 | 2012-09-18 |
5'-modified bicyclic nucleic acid analogs
Grant 8,268,980 - Seth , et al. September 18, 2 | 2012-09-18 |
Modulation of diacylglycerol acyltransferase 2 expression
Grant 8,258,289 - Bhanot , et al. September 4, 2 | 2012-09-04 |
Antisense oligonucleotides optimized for kidney targeting
Grant 8,258,105 - Siwkowski , et al. September 4, 2 | 2012-09-04 |
Modulation of glucose-6-phosphatase translocase expression
Grant 8,258,114 - Bhanot September 4, 2 | 2012-09-04 |
Compositions and methods for modulation of LMNA expression
Grant 8,258,109 - Bennett , et al. September 4, 2 | 2012-09-04 |
Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
Grant 8,252,762 - Dean , et al. August 28, 2 | 2012-08-28 |
Modulation of forkhead box O1A expression
Grant 8,227,593 - Dobie , et al. July 24, 2 | 2012-07-24 |
Mass spectrometric methods for biomolecular screening
Grant 8,211,636 - Crook , et al. July 3, 2 | 2012-07-03 |
Benzimidazoles and analogs thereof as antivirals
Grant 8,207,173 - Seth , et al. June 26, 2 | 2012-06-26 |
Compositions and their uses directed to PTPRU
Grant 8,202,981 - McKay , et al. June 19, 2 | 2012-06-19 |
Compositions and their uses directed to HBXIP
Grant 8,198,253 - Dobie , et al. June 12, 2 | 2012-06-12 |
Optimization of ligand affinity for RNA targets using mass spectrometry
Grant 8,188,011 - Griffey , et al. May 29, 2 | 2012-05-29 |
Compounds and methods for modulating expression of GCGR
Grant 8,188,059 - Bhanot , et al. May 29, 2 | 2012-05-29 |
Antisense oligonucleotide modulation of STAT3 expression
Grant 8,183,363 - Karras May 22, 2 | 2012-05-22 |
Compositions and methods for topical delivery of oligonucleotides
Grant 8,168,600 - Dokka , et al. May 1, 2 | 2012-05-01 |
Nuclease-based method for detecting and quantitating oligonucleotides
Grant 8,163,477 - Yu , et al. April 24, 2 | 2012-04-24 |
Compositions and their uses directed to PTPR alpha
Grant 8,158,598 - Bhanot , et al. April 17, 2 | 2012-04-17 |
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