Patent applications and USPTO patent grants for Ionis Pharmaceuticals, Inc..The latest application filed is for "compounds and methods for modulating angiotensinogen expression".
Patent | Date |
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Compounds And Methods For Modulating Angiotensinogen Expression App 20220298200 - Mullick; Adam ;   et al. | 2022-09-22 |
Compounds and methods for modulating angiotensinogen expression Grant 11,447,521 - Mullick , et al. September 20, 2 | 2022-09-20 |
Compounds And Methods For Reducing Spdef Expression App 20220290137 - Freier; Susan M. ;   et al. | 2022-09-15 |
2'-methoxy Substituted Oligomeric Compounds And Compositions For Use In Gene Modulations App 20220288100 - Crooke; Stanley T. | 2022-09-15 |
Compounds And Methods For Modulating Atxn1 App 20220290146 - Zhou; Keming | 2022-09-15 |
Trans-cyclooctene Labeled Antisense Oligonucleotides, Radio Labeled Tetrazine And Methods App 20220290140 - COOK; Brendon Ellery ;   et al. | 2022-09-15 |
Compounds And Methods For Modulating Cln3 Expression App 20220280545 - Hastings; Michelle L. ;   et al. | 2022-09-08 |
Compounds and methods for reducing ATXN3 expression Grant 11,434,488 - Freier September 6, 2 | 2022-09-06 |
Compositions And Methods For Modulating Ttr Expression App 20220275365 - Prakash; Thazha P. ;   et al. | 2022-09-01 |
Modulators Of Hsd17b13 Expression App 20220273691 - Freier; Susan M. ;   et al. | 2022-09-01 |
Modulation of Huntington expression Grant 11,421,231 - Hung , et al. August 23, 2 | 2022-08-23 |
Compounds And Methods For Modulating Tmprss6 Expression App 20220259600 - Guo; Shuling ;   et al. | 2022-08-18 |
Modified CRISPR RNA and modified single CRISPR RNA and uses thereof Grant 11,414,657 - Rahdar , et al. August 16, 2 | 2022-08-16 |
Synthesis Of Oligomeric Compounds Comprising Phosphorothioate Diester And Phosphodiester Linkages App 20220251128 - McPherson; Andrew K. ;   et al. | 2022-08-11 |
Methods And Compositions For Inhibiting Pmp22 Expression App 20220251553 - Hung; Gene ;   et al. | 2022-08-11 |
Modulators Of Irf4 Expression App 20220241320 - ZHOU; Tianyuan ;   et al. | 2022-08-04 |
Modulators Of Complement Factor B App 20220243209 - Grossman; Tamar R. ;   et al. | 2022-08-04 |
Modulators Of Malat1 Expression App 20220243205 - FREIER; Susan M. ;   et al. | 2022-08-04 |
Angiotensin Ii Type 1 Receptor Targeted Oligonucleotides And Uses Thereof App 20220243210 - Mullick; Adam ;   et al. | 2022-08-04 |
Compounds And Methods For Reducing Fus Expression App 20220243203 - Bui; Huynh-Hoa | 2022-08-04 |
Compositions And Methods For Modulating Tau Expression App 20220243200 - Rigo; Frank | 2022-08-04 |
Method of conjugating oligomeric compounds Grant 11,400,161 - Cedillo , et al. August 2, 2 | 2022-08-02 |
Compositions and Methods for Modulating MECP2 Expression App 20220226361 - Freier; Susan M. | 2022-07-21 |
Modulation Of Apolipoprotein C-iii (apociii) Expression In Lipoprotein Lipase Deficient (lpld) Populations App 20220213472 - Alexander; Veronica J. ;   et al. | 2022-07-07 |
Modulation of factor 11 expression Grant 11,376,273 - Freier , et al. July 5, 2 | 2022-07-05 |
Compounds And Methods For Reducing Atxn3 Expression App 20220195431 - Zhao; Hien Thuy ;   et al. | 2022-06-23 |
Compositions for Modulating Ataxin 2 Expression App 20220195430 - Freier; Susan M. | 2022-06-23 |
Modulators of EZH2 expression Grant 11,365,416 - Jo , et al. June 21, 2 | 2022-06-21 |
Compositions And Methods For Enhanced Intestinal Absorption Of Conjugated Oligomeric Compounds App 20220184112 - Searcy; Justin Drew ;   et al. | 2022-06-16 |
Linkage Modified Oligomeric Compounds And Uses Thereof App 20220186222 - Anderson; Brooke A. ;   et al. | 2022-06-16 |
Compounds And Methods For Reducing Kcnt1 Expression App 20220177893 - Bui; Huynh-Hoa ;   et al. | 2022-06-09 |
Modulation Of Prekallikrein (pkk) Expression App 20220170023 - Freier; Susan M. ;   et al. | 2022-06-02 |
Methods For Reducing Ataxin-2 Expression App 20220162615 - Rigo; Frank | 2022-05-26 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20220162603 - Allerson; Charles ;   et al. | 2022-05-26 |
Compositions for modulating C9ORF72 expression Grant 11,339,393 - Freier , et al. May 24, 2 | 2022-05-24 |
Compounds And Methods For Modulating Angiotensinogen Expression App 20220153775 - Mullick; Adam ;   et al. | 2022-05-19 |
Modified compounds and uses thereof Grant 11,332,733 - Seth , et al. May 17, 2 | 2022-05-17 |
Compounds and methods for reducing LRRK2 expression Grant 11,332,746 - Freier May 17, 2 | 2022-05-17 |
Methods Of Treating Breast Cancer App 20220143066 - Spector; David L. ;   et al. | 2022-05-12 |
Modulating apolipoprotein (a) expression Grant 11,319,536 - Viney , et al. May 3, 2 | 2022-05-03 |
Modulators of diacyglycerol acyltransferase 2 (DGAT2) Grant 11,312,962 - Bhanot , et al. April 26, 2 | 2022-04-26 |
Compositions and methods for modulating growth hormone receptor expression Grant 11,312,964 - Prakash , et al. April 26, 2 | 2022-04-26 |
Modulation Of Gys1 Expression App 20220112502 - Grossman; Tamar R. ;   et al. | 2022-04-14 |
Compounds And Methods For Reducing Pmp22 Expression App 20220112503 - Bui; Huynh-Hoa ;   et al. | 2022-04-14 |
Conjugated antisense compounds and their use Grant 11,299,736 - Prakash , et al. April 12, 2 | 2022-04-12 |
Compounds and methods for modulating SMN2 Grant 11,299,737 - Rigo April 12, 2 | 2022-04-12 |
Compositions and methods for modulating Ataxin 3 expression Grant 11,293,025 - Rigo , et al. April 5, 2 | 2022-04-05 |
Modulators of MALAT1 expression Grant 11,279,932 - Freier , et al. March 22, 2 | 2022-03-22 |
Compounds and Methods for Use in Dystrophin Transcript App 20220081689 - Rigo; Frank ;   et al. | 2022-03-17 |
Compositions And Methods For Treating And Preventing Amyotrophic Lateral Sclerosis App 20220073930 - Nestorov; Ivan Alexandrov ;   et al. | 2022-03-10 |
Compounds And Methods For Modulation Of Smn2 App 20220073914 - Rigo; Frank ;   et al. | 2022-03-10 |
Methods And Compositions For Modulating Alpha-1-antitrypsin Expression App 20220073913 - Monia; Brett P. ;   et al. | 2022-03-10 |
5' modified nucleosides and oligomeric compounds prepared therefrom Grant 11,268,094 - Prakash , et al. March 8, 2 | 2022-03-08 |
Compounds And Methods For Reducing Atxn3 Expression App 20220064637 - Freier; Susan M. | 2022-03-03 |
Modified Oligomeric Compounds And Uses Thereof App 20220064636 - Seth; Punit P. ;   et al. | 2022-03-03 |
Compounds and Methods for Reducing ATXN2 Expression App 20220064639 - Freier; Susan M. ;   et al. | 2022-03-03 |
Compounds And Methods For Modulating Smn2 App 20220064638 - Rigo; Frank ;   et al. | 2022-03-03 |
Modulation Of Hepatitis B Virus (hbv) Expression App 20220064650 - SWAYZE; Eric E. ;   et al. | 2022-03-03 |
Compounds and methods for modulating UBE3A-ATS Grant 11,261,446 - Jafar-nejad March 1, 2 | 2022-03-01 |
Compounds and methods for modulating C90RF72 Grant 11,260,073 - Prakash , et al. March 1, 2 | 2022-03-01 |
Compounds And Methods For Modulating Plp1 App 20220056445 - Powers; Berit Elissa | 2022-02-24 |
Modulators Of Irf5 Expression App 20220049248 - FREIER; Susan M. | 2022-02-17 |
Compositions And Their Uses Directed To Huntingtin App 20220042013 - Freier; Susan M. | 2022-02-10 |
Modulators of IRF4 expression Grant 11,241,451 - Zhou , et al. February 8, 2 | 2022-02-08 |
Compositions And Methods For Modulation Of Lmna Expression App 20220031731 - Singh; Priyam ;   et al. | 2022-02-03 |
Modulation of GYS1 expression Grant 11,236,339 - Grossman , et al. February 1, 2 | 2022-02-01 |
Antisense compounds and uses thereof Grant 11,236,330 - Rigo , et al. February 1, 2 | 2022-02-01 |
Selective antisense compounds and uses thereof Grant 11,236,335 - Oestergaard , et al. February 1, 2 | 2022-02-01 |
Compounds And Methods For Reducing Prion Expression App 20220025366 - Freier; Susan M. ;   et al. | 2022-01-27 |
Conjugated Antisense Compounds And Their Use App 20220023429 - Seth; Punit P. ;   et al. | 2022-01-27 |
Oligomer-conjugate Complexes And Their Use App 20220025370 - Prakash; Thazha P. ;   et al. | 2022-01-27 |
Compounds and methods for reducing SNCA expression Grant 11,230,712 - Kordasiewicz , et al. January 25, 2 | 2022-01-25 |
Modulation of angiopoietin-like 3 expression Grant 11,225,664 - Crooke , et al. January 18, 2 | 2022-01-18 |
Compounds And Methods For Modulating Angiotensinogen Expression App 20220000901 - Mullick; Adam ;   et al. | 2022-01-06 |
Modulators of YAP1 expression Grant 11,214,803 - Kim , et al. January 4, 2 | 2022-01-04 |
Compounds And Methods For Modulation Of Dystrophia Myotonica-protein Kinase (dmpk) Expression App 20210403916 - Swayze; Eric E. ;   et al. | 2021-12-30 |
Modulators of IRF5 expression Grant 11,208,650 - Freier December 28, 2 | 2021-12-28 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression App 20210395734 - Prakash; Thazha P. ;   et al. | 2021-12-23 |
Combinations for the modulation of SMN expression Grant 11,198,867 - Rigo , et al. December 14, 2 | 2021-12-14 |
Modulation of the notch signaling pathway for treatment of respiratory disorders Grant 11,197,884 - Grossman December 14, 2 | 2021-12-14 |
Chirally Enriched Oligomeric Compounds App 20210380976 - Seth; Punit P. ;   et al. | 2021-12-09 |
Compositions for modulating expression of C9ORF72 antisense transcript Grant 11,193,128 - Rigo December 7, 2 | 2021-12-07 |
Morpholino modified oligomeric compounds Grant 11,180,756 - Oestergaard , et al. November 23, 2 | 2021-11-23 |
Oligonucleotide Mediated No-go Decay App 20210355493 - Liang; Xue-hai ;   et al. | 2021-11-18 |
Compounds And Methods For Reducing Fxi Expression App 20210355497 - Bui; Huynh-Hoa | 2021-11-18 |
Allele Specific Modulators Of P23h Rhodopsin App 20210346421 - Murray; Susan F. ;   et al. | 2021-11-11 |
GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof App 20210346509 - Monia; Brett P. ;   et al. | 2021-11-11 |
Methods For Reducing Lrrk2 Expression App 20210340546 - Zhao; Hien Thuy ;   et al. | 2021-11-04 |
Methods for modulating expression of C9ORF72 antisense transcript Grant 11,162,096 - Bennett , et al. November 2, 2 | 2021-11-02 |
Compositions and methods for modulating Tau expression Grant 11,155,815 - Rigo October 26, 2 | 2021-10-26 |
Modified compounds and uses thereof Grant 11,149,264 - Seth , et al. October 19, 2 | 2021-10-19 |
Compounds and Methods for Modulation of Transcript Processing App 20210315918 - Prakash; Thazha P. ;   et al. | 2021-10-14 |
Methods and compositions for inhibiting PMP22 expression Grant 11,136,577 - Hung , et al. October 5, 2 | 2021-10-05 |
Compositions and methods for modulating MECP2 expression Grant 11,129,844 - Freier , et al. September 28, 2 | 2021-09-28 |
Modulation Of Lnc05 Expression App 20210290653 - Yu; Allen Tingjin ;   et al. | 2021-09-23 |
Method Of Conjugating Oligomeric Compounds App 20210283263 - Cedillo; Isaiah E. ;   et al. | 2021-09-16 |
Methods For Treating Hypercholesterolemia App 20210285003 - Freier; Susan M. ;   et al. | 2021-09-16 |
Conjugated antisense compounds and their use Grant 11,116,843 - Seth , et al. September 14, 2 | 2021-09-14 |
Modulation of angiopoietin-like 3 expression Grant 11,118,183 - Freier , et al. September 14, 2 | 2021-09-14 |
Compositions and Methods for Modulating PKK Expression App 20210277401 - Prakash; Thazha P. ;   et al. | 2021-09-09 |
Methods For Safely Reducing Thrombopoietin App 20210275569 - Gruber; Andras ;   et al. | 2021-09-09 |
Compounds And Methods For Modulating Ube3a-ats App 20210277397 - Freier; Susan M. ;   et al. | 2021-09-09 |
Compositions for modulating Ataxin 2 expression Grant 11,111,494 - Freier September 7, 2 | 2021-09-07 |
Compounds and Methods for the Modulation of Proteins App 20210269472 - Crooke; Stanley T. ;   et al. | 2021-09-02 |
Oligomer-conjugate complexes and their use Grant 11,104,899 - Prakash , et al. August 31, 2 | 2021-08-31 |
Modified Compounds and Uses Thereof App 20210261945 - Seth; Punit P. ;   et al. | 2021-08-26 |
Compounds And Methods For Increasing Stmn2 Expression App 20210252039 - Bui; Huynh-Hoa ;   et al. | 2021-08-19 |
Linkage Modified Oligomeric Compounds App 20210254059 - Migawa; Michael T. ;   et al. | 2021-08-19 |
Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom Grant 11,084,844 - Prakash , et al. August 10, 2 | 2021-08-10 |
Selective Antisense Compounds and Uses Thereof App 20210238591 - Seth; Punit P. ;   et al. | 2021-08-05 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 11,078,485 - Allerson , et al. August 3, 2 | 2021-08-03 |
Compounds and methods for reducing ATXN2 expression Grant 11,078,486 - Jafar-nejad August 3, 2 | 2021-08-03 |
Compositions for Modulating C9ORF72 Expression App 20210230589 - Rigo; Frank | 2021-07-29 |
Compositions and their uses directed to huntingtin Grant 11,072,794 - Freier July 27, 2 | 2021-07-27 |
Compositions and methods for modulation of IKBKAP splicing Grant 11,066,668 - Bennett , et al. July 20, 2 | 2021-07-20 |
Compositions For Modulating Expression Of C9orf72 Antisense Transcript App 20210214725 - Rigo; Frank | 2021-07-15 |
Methods of treating breast cancer Grant 11,058,709 - Spector , et al. July 13, 2 | 2021-07-13 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20210207146 - Prakash; Thazha P. ;   et al. | 2021-07-08 |
Modulation of prekallikrein (PKK) expression Grant 11,053,500 - Freier , et al. July 6, 2 | 2021-07-06 |
MODULATORS OF ENaC EXPRESSION App 20210180057 - Crosby; Jeffrey R. ;   et al. | 2021-06-17 |
Modulation of Lnc05 expression Grant 11,033,570 - Yu , et al. June 15, 2 | 2021-06-15 |
Methods For Reducing C9orf72 Expression App 20210169916 - Bennett; C. Frank ;   et al. | 2021-06-10 |
Methods Of Modulating Antisense Activity App 20210171945 - Liang; Xue-hai ;   et al. | 2021-06-10 |
Conjugated Antisense Compounds for Use in Therapy App 20210169917 - Viney; Nicholas J. ;   et al. | 2021-06-10 |
Modulation Of Factor 11 Expression App 20210169921 - Freier; Susan M. ;   et al. | 2021-06-10 |
Compounds and methods for reducing FXI expression Grant 11,021,710 - Bui June 1, 2 | 2021-06-01 |
Modulators Of Ezh2 Expression App 20210155935 - Jo; Minji ;   et al. | 2021-05-27 |
Allele specific modulators of P23H rhodopsin Grant 11,013,758 - Murray , et al. May 25, 2 | 2021-05-25 |
Selective Antisense Compounds and Uses Thereof App 20210147838 - Seth; Punit P. ;   et al. | 2021-05-20 |
Oligomeric Compounds Comprising Bicyclic Nucleotides and Uses Thereof App 20210147837 - Freier; Susan M. ;   et al. | 2021-05-20 |
Compounds And Methods For Reducing Spdef Expression App 20210139906 - Freier; Susan M. ;   et al. | 2021-05-13 |
Modulation Of Huntingtin Expression App 20210139900 - Hung; Gene ;   et al. | 2021-05-13 |
Modulators of PCSK9 expression Grant 11,000,595 - Swayze , et al. May 11, 2 | 2021-05-11 |
Compositions And Methods App 20210130823 - Prakash; Thazha P. ;   et al. | 2021-05-06 |
Methods Of Modulating Antisense Activity App 20210130826 - OCHABA, JR.; Joseph ;   et al. | 2021-05-06 |
Modulators Of Yap1 Expression App 20210123059 - Kim; Youngsoo ;   et al. | 2021-04-29 |
Modulation Of Transthyretin Expression App 20210095281 - Monia; Brett P. ;   et al. | 2021-04-01 |
Methods of modulating KEAP1 Grant 10,961,271 - Lee , et al. March 30, 2 | 2021-03-30 |
Modulation Of Frataxin Expression App 20210087559 - RIGO; Frank ;   et al. | 2021-03-25 |
Modulation Of Alpha Synuclein Expression App 20210087562 - Freier; Susan M. | 2021-03-25 |
Compounds And Methods For Reducing Fxi Expression App 20210087569 - Bui; Huynh-Hoa | 2021-03-25 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION App 20210087566 - PRAKASH; Thazha P. ;   et al. | 2021-03-25 |
Compounds and methods for modulation of dystrophia myotonica-protein kinase (DMPK) expression Grant 10,954,519 - Swayze , et al. March 23, 2 | 2021-03-23 |
Modulators Of Pnpla3 Expression App 20210079401 - FREIER; Susan M. ;   et al. | 2021-03-18 |
Modulators of PCSK9 Expression App 20210077630 - Swayze; Eric E. ;   et al. | 2021-03-18 |
Modulators of APOL1 Expression App 20210079395 - FREIER; Susan M. | 2021-03-18 |
Antisense Oligonucleotide Compositions App 20210079391 - Dibble; Andrew ;   et al. | 2021-03-18 |
Modulation of androgen receptor expression Grant RE48,461 - Macleod , et al. March 9, 2 | 2021-03-09 |
Conjugated Antisense Compounds And Their Use App 20210054017 - Seth; Punit P. ;   et al. | 2021-02-25 |
Conjugated Antisense Compounds And Their Use App 20210052631 - Prakash; Thazha P. ;   et al. | 2021-02-25 |
Modulators of APOL1 expression Grant 10,927,377 - Freier February 23, 2 | 2021-02-23 |
Compositions and methods for modulating apolipoprotein C-III expression Grant 10,927,372 - Prakash , et al. February 23, 2 | 2021-02-23 |
Compounds And Methods For Modulating Gfap App 20210038629 - Powers; Berit Elissa ;   et al. | 2021-02-11 |
Modulators Of Irf4 Expression App 20210038631 - Zhou; Tianyuan ;   et al. | 2021-02-11 |
Compounds And Methods For The Modulation Of Amyloid-beta Precursor Protein App 20210040480 - Rigo; Frank ;   et al. | 2021-02-11 |
Compounds and methods for modulating angiotensinogen expression Grant 10,912,792 - Mullick , et al. February 9, 2 | 2021-02-09 |
Methods for reducing LRRK2 expression Grant 10,907,160 - Zhao , et al. February 2, 2 | 2021-02-02 |
Compositions And Methods For Modulating Ttr Expression App 20210024923 - Prakash; Thazha P. ;   et al. | 2021-01-28 |
Compositions And Their Uses Directed To Huntingtin App 20210017522 - Hung; Gene ;   et al. | 2021-01-21 |
Modified Compounds And Uses Thereof App 20210017513 - Seth; Punit P. ;   et al. | 2021-01-21 |
Modulation Of Hsd17b13 Expression App 20210000906 - Murray; Susan F. ;   et al. | 2021-01-07 |
Methods And Compositions For Modulating Apolipoprotein (a) Expression App 20210002643 - Crooke; Rosanne M. ;   et al. | 2021-01-07 |
Methods For Modulating Fmr1 Expression App 20210002642 - RIGO; Frank ;   et al. | 2021-01-07 |
Selective Antisense Compounds and Uses Thereof App 20210002636 - Oestergaard; Michael ;   et al. | 2021-01-07 |
Compositions and methods for modulating apolipoprotein (a) expression Grant 10,883,104 - Prakash , et al. January 5, 2 | 2021-01-05 |
Methods Of Modulating Antisense Activity App 20200407717 - Wang; Shiyu ;   et al. | 2020-12-31 |
Compositions and methods for modulating angiopoietin-like 3 expression Grant 10,875,884 - Prakash , et al. December 29, 2 | 2020-12-29 |
Oligomeric Compounds Comprising Bicyclic Nucleotides and Uses Thereof App 20200392493 - Freier; Susan M. ;   et al. | 2020-12-17 |
Conjugated Antisense Compounds And Their Use App 20200392509 - Oestergaard; Michael ;   et al. | 2020-12-17 |
Compounds And Methods For Reducing Snca Expression App 20200392494 - Kordasiewicz; Holly ;   et al. | 2020-12-17 |
Modulators Of Dnm2 Expression App 20200392510 - FREIER; Susan M. ;   et al. | 2020-12-17 |
Modulators of DNM2 expression Grant 10,865,414 - Freier December 15, 2 | 2020-12-15 |
Oligomeric compounds comprising .alpha.-.beta.-constrained nucleic acid Grant 10,865,413 - Oestergaard , et al. December 15, 2 | 2020-12-15 |
5' Modified Nucleosides And Oligomeric Compounds Prepared Therefrom App 20200385722 - Prakash; Thazha P. ;   et al. | 2020-12-10 |
Methods for treating hypercholesterolemia Grant 10,858,657 - Freier , et al. December 8, 2 | 2020-12-08 |
Selective Reduction of Allelic Variants App 20200377946 - Bennett; C. Frank ;   et al. | 2020-12-03 |
Modulation of SMN expression Grant 10,851,371 - Rigo , et al. December 1, 2 | 2020-12-01 |
Conjugated antisense compounds and their use Grant 10,844,379 - Prakash , et al. November 24, 2 | 2020-11-24 |
Modulation of Dystrophia Myotonica-Protein Kinase (DMPK) Expression App 20200362353 - Bennett; C. Frank ;   et al. | 2020-11-19 |
Modulation of huntingtin expression Grant 10,837,016 - Hung , et al. November 17, 2 | 2020-11-17 |
Compounds and methods for the modulation of proteins Grant 10,822,369 - Crooke , et al. November 3, 2 | 2020-11-03 |
Compositions for modulating C9ORF72 expression Grant 10,815,483 - Rigo October 27, 2 | 2020-10-27 |
Modulation of alpha synuclein expression Grant 10,815,480 - Freier October 27, 2 | 2020-10-27 |
Compositions And Methods For Modulating Ataxin 3 Expression App 20200325473A1 - | 2020-10-15 |
Compositions And Their Uses Directed To Huntingtin App 20200318116A1 - | 2020-10-08 |
Cancer Treatment App 20200318112A1 - | 2020-10-08 |
Compositions for modulating expression of C9ORF72 antisense transcript Grant 10,793,855 - Rigo October 6, 2 | 2020-10-06 |
Compositions and methods for modulating growth hormone receptor expression Grant 10,793,862 - Prakash , et al. October 6, 2 | 2020-10-06 |
Combinations For The Modulation Of Smn Expression App 20200308580A1 - | 2020-10-01 |
Modulation of Factor 11 expression Grant 10,772,906 - Freier Sept | 2020-09-15 |
Modulators of PNPLA3 expression Grant 10,774,333 - Freier , et al. September 15, 2 | 2020-09-15 |
Methods And Compositions For Modulating Apolipoprotein (a) Expression App 20200276224A1 - | 2020-09-03 |
Modulators Of Malat1 Expression App 20200277604A1 - | 2020-09-03 |
2'-methoxy Substituted Oligomeric Compounds And Compositions For Use In Gene Modulations App 20200276222A1 - | 2020-09-03 |
Antisense Compounds App 20200276221A1 - | 2020-09-03 |
Single-Stranded RNAI Oligonucleotides Targeting APOC-III App 20200270609A1 - | 2020-08-27 |
Modulation Of Huntingtin Expression App 20200270608A1 - | 2020-08-27 |
Glp-1 Receptor Ligand Moiety Conjugated Oligonucleotides And Uses Thereof App 20200268898A1 - | 2020-08-27 |
Compounds and methods for detecting oligonucleotides Grant 10,752,940 - Greenlee , et al. A | 2020-08-25 |
Method for synthesis of reactive conjugate clusters Grant 10,751,419 - Migawa , et al. A | 2020-08-25 |
Methods of predicting toxicity Grant 10,745,756 - Burel A | 2020-08-18 |
Compositions and their uses directed to huntingtin Grant 10,738,307 - Hung , et al. A | 2020-08-11 |
Morpholino Modified Oligomeric Compounds App 20200239881A1 - | 2020-07-30 |
Compositions For Modulating C9orf72 Expression App 20200239882A1 - | 2020-07-30 |
Compositions And Methods For Modulation Of Protein Aggregation App 20200239888A1 - | 2020-07-30 |
Compositions for Modulating Expression of C9ORF72 Antisense Transcript App 20200239883A1 - | 2020-07-30 |
Compositions And Methods For Modulating Hbv Expression App 20200224198A1 - | 2020-07-16 |
Antisense Compounds and Uses Thereof App 20200216846A1 - | 2020-07-09 |
Modulators Of Irf5 Expression App 20200208147A1 - | 2020-07-02 |
Modulators of PCSK9 Expression App 20200197525A1 - | 2020-06-25 |
Antisense modulation of PTP1B expression Grant RE48,060 - Bhanot , et al. | 2020-06-23 |
Compounds And Methods For Modulating Tmprss6 Expression App 20200190522A1 - | 2020-06-18 |
Modulation Of Hepatitis B Virus (hbv) Expression App 20200190520A1 - | 2020-06-18 |
Compositions and methods for modulating TTR expression Grant 10,683,499 - Prakash , et al. | 2020-06-16 |
Modulators Of Foxp3 Expression App 20200179435A1 - | 2020-06-11 |
5' modified nucleosides and oligomeric compounds prepared therefrom Grant 10,676,738 - Prakash , et al. | 2020-06-09 |
Modulation Of The Notch Signaling Pathway For Treatment Of Respiratory Disorders App 20200171071A1 - | 2020-06-04 |
Methods And Compositions For Modulating Alpha-1-antitrypsin Expression App 20200157535A1 - | 2020-05-21 |
Compositions And Methods For Enhanced Intestinal Absorption Of Conjugated Oligomeric Compounds App 20200157548A1 - | 2020-05-21 |
Compositions and their uses directed to huntingtin Grant 10,655,129 - Freier | 2020-05-19 |
Modulators Of Complement Factor B App 20200149047A1 - | 2020-05-14 |
Modulators Of Pnpla3 Expression App 20200140869A1 - | 2020-05-07 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20200123551A1 - | 2020-04-23 |
Modulation Of Angiopoietin-like 3 Expression App 20200115711A1 - | 2020-04-16 |
Method for solution phase detritylation of oligomeric compounds Grant 10,618,931 - Chreng | 2020-04-14 |
Modulation of huntingtin expression Grant 10,619,158 - Hung , et al. | 2020-04-14 |
Cancer treatment Grant 10,619,157 - Crooke , et al. | 2020-04-14 |
Modulation Of Apolipoprotein C-iii (apociii) Expression In Lipodystrophy Populations App 20200095581A1 - | 2020-03-26 |
Compositions For Modulating Ataxin 2 Expression App 20200087661A1 - | 2020-03-19 |
Compositions and methods for modulation nucleic acids through nonsense mediated decay Grant 10,590,412 - Ward , et al. | 2020-03-17 |
Compositions and Methods for Modulating MECP2 Expression App 20200078389A1 - | 2020-03-12 |
Allele Specific Modulators Of P23h Rhodopsin App 20200069722A1 - | 2020-03-05 |
Methods for monitoring C9ORF72 expression Grant 10,577,604 - Bennett , et al. | 2020-03-03 |
Modulation of DYRK1B expression Grant 10,577,607 - Monia , et al. | 2020-03-03 |
Conjugated antisense compounds and their use Grant 10,570,169 - Seth , et al. Feb | 2020-02-25 |
Selective Antisense Compounds And Uses Thereof App 20200056187A1 - | 2020-02-20 |
Compositions And Methods For Modulating Pkk Expression App 20200056185A1 - | 2020-02-20 |
Compounds And Methods For Reducing Atxn2 Expression App 20200056179A1 - | 2020-02-20 |
Modulation Of Apolipoprotein Ciii (apociii) Expression App 20200056176A1 - | 2020-02-20 |
Compositions And Methods For Modulating Complement Factor B Expression App 20200048638A1 - | 2020-02-13 |
Modulating apolipoprotein (a) expression Grant 10,557,137 - Viney , et al. Feb | 2020-02-11 |
Modulators Of Diacyglycerol Acyltransferase 2 (dgat2) App 20200040341A1 - | 2020-02-06 |
Compositions And Methods For Modulation Of Ikbkap Splicing App 20200032260A1 - | 2020-01-30 |
Compounds and methods for modulation of DUX4 Grant 10,538,763 - Rigo , et al. Ja | 2020-01-21 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20200017855A1 - | 2020-01-16 |
Modulation Of Apolipoprotein C-iii (apociii) Expression In Lipoprotein Lipase Deficient (lpld) Populations App 20200017854A1 - | 2020-01-16 |
Compositions and methods for modulating Ataxin 3 expression Grant 10,533,175 - Rigo , et al. Ja | 2020-01-14 |
Methods for modulating Ataxin 2 expression Grant 10,533,178 - Bennett , et al. Ja | 2020-01-14 |
Modulation of nuclear-retained RNA Grant 10,526,604 - Bennett , et al. J | 2020-01-07 |
Modulation Of Factor 11 Expression App 20200000839A1 - | 2020-01-02 |
Modulators of SMAD7 expression Grant 10,517,889 - Freier , et al. Dec | 2019-12-31 |
Modulators of PCSK9 expression Grant 10,517,953 - Swayze , et al. Dec | 2019-12-31 |
Antisense Compounds Targeting Genes Associated With Fibronectin App 20190382760A1 - | 2019-12-19 |
Modified Crispr Rna And Uses Thereof App 20190382751A1 - | 2019-12-19 |
Compositions For Modulating C9orf72 Expression App 20190367916A1 - | 2019-12-05 |
Conjugated Antisense Compounds And Their Use App 20190367914A1 - | 2019-12-05 |
Antisense compounds Grant 10,493,092 - Swayze De | 2019-12-03 |
Modulation of signal transducer and activator of transcription 3 (STAT3) expression Grant 10,479,993 - Swayze , et al. Nov | 2019-11-19 |
Methods and compositions for modulating apolipoprotein (a) expression Grant 10,478,448 - Crooke , et al. Nov | 2019-11-19 |
2'-methoxy substituted oligomeric compounds and compositions for use in gene modulations Grant 10,478,449 - Crooke Nov | 2019-11-19 |
Antisense compounds targeting apolipoprotein E receptor 2 Grant 10,472,634 - Rigo , et al. Nov | 2019-11-12 |
Methods and compositions for modlating apolipoprotein (A) expression Grant 10,472,629 - Crooke , et al. Nov | 2019-11-12 |
Method for solution phase detritylation of oligomeric compounds Grant 10,450,342 - Chreng , et al. Oc | 2019-10-22 |
Compositions for modulating C9ORF72 expression Grant 10,443,052 - Freier Oc | 2019-10-15 |
Methods and compounds useful in conditions related to repeat expansion Grant 10,435,430 - Prakash , et al. O | 2019-10-08 |
Allele specific modulators of P23H rhodopsin Grant 10,426,789 - Murray , et al. October 1, 2 | 2019-10-01 |
Compounds and methods for modulating TMPRSS6 expression Grant 10,415,038 - Guo , et al. Sept | 2019-09-17 |
NCAGE Code | 09HU6 | IONIS PHARMACEUTICALS, INC. |
CAGE Code | 09HU6 | IONIS PHARMACEUTICALS, INC. |
S.A.M. Registration | 09HU6 [361949092] | IONIS PHARMACEUTICALS, INC. |
SEC | 0000874015 | IONIS PHARMACEUTICALS INC of DELAWARE |
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