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Cellular Immunotherapy For Repetitive Administration App 20220233588 - SOURDIVE; David ;   et al. | 2022-07-28 |
Methods for engineering T cells for immunotherapy by using RNA-guided Cas nuclease system Grant 11,365,430 - Duchateau , et al. June 21, 2 | 2022-06-21 |
Chimeric antigen receptors targeting B-cell maturation antigen Grant 11,312,782 - Kuo , et al. April 26, 2 | 2022-04-26 |
Method For The Generation Of Compact Tale-nucleases And Uses Thereof App 20220010292 - Duchateau; Philippe ;   et al. | 2022-01-13 |
Method to overcome DNA chemical modifications sensitivity of engineered TALE DNA binding domains Grant 11,220,683 - Duchateau , et al. January 11, 2 | 2022-01-11 |
Method for the generation of compact tale-nucleases and uses thereof Grant 11,198,856 - Duchateau , et al. December 14, 2 | 2021-12-14 |
Methods for engineering allogeneic T cell to increase their persistence and/or engraftment into patients Grant 11,186,824 - Duchateau , et al. November 30, 2 | 2021-11-30 |
Tale-protein scaffolds and uses thereof Grant 11,136,566 - Duchateau , et al. October 5, 2 | 2021-10-05 |
Universal Anti-cd22 Chimeric Antigen Receptor Engineered Immune Cells App 20210161954 - Smith; Julianne ;   et al. | 2021-06-03 |
Anti-CLL1 specific single-chain chimeric antigen receptors (scCARs) for cancer immunotherapy Grant 11,014,989 - Smith , et al. May 25, 2 | 2021-05-25 |
Methods For Engineering T Cells For Immunotherapy By Using Rna-guided Cas Nuclease System App 20210147868 - DUCHATEAU; Philippe ;   et al. | 2021-05-20 |
Anti-hbv Combination Therapies Involving Specific Endonucleases App 20210139870 - DUCHATEAU; Philippe | 2021-05-13 |
Engineered Immune Cells Resistant To Tumor Microenvironment App 20210128613 - DUCHATEAU; Philippe ;   et al. | 2021-05-06 |
Chimeric antigen receptors with integrated controllable functions Grant 10,988,542 - Juillerat , et al. April 27, 2 | 2021-04-27 |
New Universal Chimeric Antigen Receptor T Cells Specific For Cd22 App 20210100839 - Schiffer-Mannioui; Cecile ;   et al. | 2021-04-08 |
Tale-nucleases For Allele-specific Codon Modification And Multiplexing App 20210017545 - BOYNE; Alex ;   et al. | 2021-01-21 |
Method of engineering drug-specific hypersensitive t-cells for immunotherapy by gene inactivation Grant 10,894,093 - Valton , et al. January 19, 2 | 2021-01-19 |
Targeted Gene Integration Of Crs Inhibitor Genes For Improved Immune Cells Therapy App 20200407694 - BUSSER; Brian ;   et al. | 2020-12-31 |
Cells For Immunotherapy Engineered For Targeting Antigen Present Both On Immune Cells And Pathological Cells App 20200407682 - DUCHATEAU; Philippe ;   et al. | 2020-12-31 |
Methods for engineering T cells for immunotherapy by using RNA-guided Cas nuclease system Grant 10,870,864 - Duchateau , et al. December 22, 2 | 2020-12-22 |
New Sequence Specific Reagents Targeting Ccr5 In Primary Hematopoietic Cells App 20200392459 - CATHOMEN; Toni ;   et al. | 2020-12-17 |
Cells for immunotherapy engineered for targeting antigen present both on immune cells and pathological cells Grant 10,836,998 - Duchateau , et al. November 17, 2 | 2020-11-17 |
Transcription activator-like effector (TALE) fusion protein Grant 10,815,500 - Juillerat , et al. October 27, 2 | 2020-10-27 |
Method of engineering chemotherapy drug resistant T-cells for immunotherapy Grant 10,813,951 - Valton , et al. October 27, 2 | 2020-10-27 |
Method For Improving Production Of Car T Cells App 20200332004 - BOYNE; Alex ;   et al. | 2020-10-22 |
Methods For Engineering T Cells For Immunotherapy By Using Rna-guided Cas Nuclease System App 20200277625 - DUCHATEAU; Philippe ;   et al. | 2020-09-03 |
Targeted Gene Integration Of Nk Inhibitors Genes For Improved Immune Cells Therapy App 20200237823 - BUSSER; Brian ;   et al. | 2020-07-30 |
Targeted Gene Insertion For Improved Immune Cells Therapy App 20200224163 - BUSSER; Brian ;   et al. | 2020-07-16 |
Methods Of Antigen-dependent Chimeric Antigen Receptor (car) Immune Cell Selection App 20200216515 - DUCHATEAU; Philippe ;   et al. | 2020-07-09 |
Sequential Gene Editing In Primary Immune Cells App 20200208174 - CABANIOLS; Jean-Pierre ;   et al. | 2020-07-02 |
Methods For Engineering T Cells For Immunotherapy By Using Rna-guided Cas Nuclease System App 20200181643 - DUCHATEAU; Philippe ;   et al. | 2020-06-11 |
Protease Based Switch Chimeric Antigen Receptors For Safer Cell Immunotherapy App 20200140560 - Duchateau; Philippe ;   et al. | 2020-05-07 |
Methods for engineering T cells for immunotherapy by using RNA-guided Cas nuclease system Grant 10,584,352 - Duchateau , et al. | 2020-03-10 |
Chimeric antigen receptor using antigen recognition domains derived from cartilaginous fish Grant 10,526,406 - Duchateau , et al. J | 2020-01-07 |
Rare-cutting endonucleases for efficient and specific targeting DNA sequences comprising highly repetitive motives Grant 10,508,289 - Duchateau , et al. Dec | 2019-12-17 |
Modular base-specific nucleic acid binding domains from burkholderia rhizoxinica proteins Grant 10,472,396 - Bertonati , et al. Nov | 2019-11-12 |
Method for modulating car-induced immune cells activity Grant 10,472,613 - Duchateau , et al. Nov | 2019-11-12 |
Method To Overcome Dna Chemical Modifications Sensitivity Of Engineered Tale Dna Binding Domains App 20190338273 - DUCHATEAU; Philippe ;   et al. | 2019-11-07 |
Cell Death Inducing Chimeric Antigen Receptors App 20190338015 - JUILLERAT; Alexandre ;   et al. | 2019-11-07 |
A Method Of Engineering Prodrug-specific Hypersensitive T-cells For Immunotherapy By Gene Expression App 20190328783 - VALTON; Julien ;   et al. | 2019-10-31 |
Tale-protein Scaffolds And Uses Thereof App 20190316100 - Duchateau; Philippe ;   et al. | 2019-10-17 |
Stably Enginereed Proteasome Inhibitor Resistant Immune Cells For Immunotherapy App 20190290694 - GAUTRON; Anne-Sophie ;   et al. | 2019-09-26 |
Methods for modulating TAL specificity Grant 10,378,007 - Juillerat , et al. A | 2019-08-13 |
Chimeric Antigen Receptors Targeting B-cell Maturation Antigen App 20190241669 - KUO; Tracy Chia-Chien ;   et al. | 2019-08-08 |
Method to overcome DNA chemical modifications sensitivity of engineered tale DNA binding domains Grant 10,301,614 - Duchateau , et al. | 2019-05-28 |
A Method Of Engineering Drug-specific Hypersensitive T-cells For Immunotherapy By Gene Inactivation App 20190151478 - VALTON; Julien ;   et al. | 2019-05-23 |
Chimeric antigen receptors targeting B-cell maturation antigen Grant 10,294,304 - Kuo , et al. | 2019-05-21 |
Method of engineering multi-input signal sensitive T cell for immunotherapy Grant 10,239,948 - Juillerat , et al. | 2019-03-26 |
Method for in situ inhibition of regulatory T cells Grant 10,196,608 - Poirot , et al. Fe | 2019-02-05 |
Micelle Based System Nuclease Encapsulation For In-vivo Gene Editing App 20190032088 - DUCHATEAU; Philippe ;   et al. | 2019-01-31 |
Primary Hematopoietic Cells Genetically Engineered By Slow Release Of Nucleic Acids Using Nanoparticles App 20190024065 - DELACOTE; Fabien ;   et al. | 2019-01-24 |
Method For Generating T-cells Compatible For Allogenic Transplantation App 20190010514 - POIROT; Laurent ;   et al. | 2019-01-10 |
Method For Producing Precise Dna Cleavage Using Cas9 Nickase Activity App 20180327761 - DUCHATEAU; Philippe ;   et al. | 2018-11-15 |
Methods For Engineering Allogeneic T Cell To Increase Their Persistence And/or Engraftment Into Patients App 20180291343 - DUCHATEAU; Philippe ;   et al. | 2018-10-11 |
Modified diatoms for biofuel production Grant 10,087,453 - Duchateau , et al. October 2, 2 | 2018-10-02 |
Chimeric Antigen Receptors With Integrated Controllable Functions App 20180237533 - JUILLERAT; Alexandre ;   et al. | 2018-08-23 |
Methods For Engineering T Cells For Immunotherapy By Using Rna-guided Cas Nuclease System App 20180237798 - DUCHATEAU; Philippe ;   et al. | 2018-08-23 |
Method For In Situ Inhibition Of Regulatory T Cells App 20180208896 - POIROT; Laurent ;   et al. | 2018-07-26 |
Cells For Immunotherapy Engineered For Targeting Antigen Present Both On Immune Cells And Pathological Cells App 20180201901 - DUCHATEAU; Philippe ;   et al. | 2018-07-19 |
Methods For Improving Functionality In Nk Cell By Gene Inactivation Using Specific Endonuclease App 20180171298 - DUCHATEAU; Philippe ;   et al. | 2018-06-21 |
T Cell Receptor Knock Out Engineered Immune Cells, Endowed With Chimeric Antigen Receptors Binding To Cd123 For The Treatment Of Relapsed/refractory Acute Myeloid Lymphoma Or Blastic Plasmacytoid Dendritic Cell Neoplasm App 20180051089 - GALETTO; Roman ;   et al. | 2018-02-22 |
Methods for engineering T cells for immunotherapy by using RNA-guided CAS nuclease system Grant 9,890,393 - Duchateau , et al. February 13, 2 | 2018-02-13 |
Anti-cll1 Specific Single-chain Chimeric Antigen Receptors (sccars) For Cancer Immunotherapy App 20180009895 - SMITH; Julianne ;   et al. | 2018-01-11 |
Anti-hsp70 Specific Chimeric Antigen Receptors (cars) For Cancer Immunotherapy App 20180000914 - VALTON; Julien ;   et al. | 2018-01-04 |
mAb-DRIVEN CHIMERIC ANTIGEN RECEPTOR SYSTEMS FOR SORTING/DEPLETING ENGINEERED IMMUNE CELLS App 20180002435 - SASU; Barbara Johnson ;   et al. | 2018-01-04 |
Cll1-specific Multi-chain Chimeric Antigen Receptor App 20180002427 - SMITH; Julianne ;   et al. | 2018-01-04 |
Methods for engineering T cells for immunotherapy by using RNA-guided CAS nuclease system Grant 9,855,297 - Duchateau , et al. January 2, 2 | 2018-01-02 |
INHIBITORY CHIMERIC ANTIGEN RECEPTOR (iCAR OR N-CAR) EXPRESSING NON-T CELL TRANSDUCTION DOMAIN App 20170296623 - JUILLERAT; Alexandre ;   et al. | 2017-10-19 |
Method For Modulating Car-induced Immune Cells Activity App 20170292118 - DUCHATEAU; Philippe ;   et al. | 2017-10-12 |
Engineering Mammalian Genome Using Dna-guided Argonaute Interference Systems (dais) App 20170198306 - Valton; Julien ;   et al. | 2017-07-13 |
Method Of Engineering Multi-input Signal Sensitive T Cell For Immunotherapy App 20170073423 - JUILLERAT; Alexandre ;   et al. | 2017-03-16 |
Method For In Situ Inhibition Of Regulatory T Cells App 20170067022 - Poirot; Laurent ;   et al. | 2017-03-09 |
Method For Generating T-cells Compatible For Allogenic Transplantation App 20170016025 - POIROT; Laurent ;   et al. | 2017-01-19 |
Method Of Engineering Chemotherapy Drug Resistant T-cells For Immunotherapy App 20160361359 - VALTON; Julien ;   et al. | 2016-12-15 |
Methods And Kits For Detecting Nucleic Acid Sequences Of Interest Using Dna-binding Protein Domain App 20160355875 - VALTON; Julien ;   et al. | 2016-12-08 |
Chimeric Antigen Receptor Using Antigen Recognition Domains Derived From Cartilaginous Fish App 20160333094 - DUCHATEAU; Philippe ;   et al. | 2016-11-17 |
New Method Of Selection Of Algal-transformed Cells Using Nuclease App 20160312233 - DUCHATEAU; Philippe ;   et al. | 2016-10-27 |
Chimeric Antigen Receptors Targeting B-cell Maturation Antigen App 20160297884 - KUO; TRACY CHIA-CHIEN ;   et al. | 2016-10-13 |
Method For The Generation Of Compact Tale-nucleases And Uses Thereof App 20160298098 - Duchateau; Philippe ;   et al. | 2016-10-13 |
Use Of Meganucelases For Inducing Homologous Recombination Ex Vivo And In Toto In Vertebrate Somatic Tissues And Application Thereof App 20160273003 - DUCHATEAU; Philippe ;   et al. | 2016-09-22 |
Method For Targeted Modification Of Algae Genomes App 20160272980 - DUCHATEAU; Philippe ;   et al. | 2016-09-22 |
Methods For Engineering T Cells For Immunotherapy By Using Rna-guided Cas Nuclease System App 20160272999 - DUCHATEAU; Philippe ;   et al. | 2016-09-22 |
Design Of Rare-cutting Endonucleases For Efficient And Specific Targeting Dna Sequences Comprising Highly Repetitive Motives App 20160273002 - DUCHATEAU; Philippe ;   et al. | 2016-09-22 |
Methods For Engineering T Cells For Immunotherapy By Using Rna-guided Cas Nuclease System App 20160184362 - DUCHATEAU; Philippe ;   et al. | 2016-06-30 |
Improved Polynucleotide Sequences Encoding Tale Repeats App 20160138047 - DUCHATEAU; Philippe ;   et al. | 2016-05-19 |
Modified Diatoms For Biofuel Production App 20160130599 - DUCHATEAU; Philippe ;   et al. | 2016-05-12 |
A Method For Producing Precise Dna Cleavage Using Cas9 Nickase Activity App 20160122774 - DUCHATEAU; Philippe ;   et al. | 2016-05-05 |
Method for the generation of compact TALE-nucleases and uses thereof Grant 9,315,788 - Duchateau , et al. April 19, 2 | 2016-04-19 |
New Compact Scaffold Of Cas9 In The Type Ii Crispr System App 20160102324 - DUCHATEAU; Philippe ;   et al. | 2016-04-14 |
New Modular Base-specific Nucleic Acid Binding Domains From Burkholderia Rhizoxinica Proteins App 20150225465 - BERTONATI; Claudia ;   et al. | 2015-08-13 |
Methods For Modulating Tal Specificity App 20150218230 - Juillerat; Alexandre ;   et al. | 2015-08-06 |
Transcription Activator-Like Effector (TALE) Fusion Protein App 20150203871 - Juillerat; Alexandre ;   et al. | 2015-07-23 |
Method for modulating the efficiency of double-strand break-induced mutagenesis Grant 9,044,492 - Delacote , et al. June 2, 2 | 2015-06-02 |
New Repeat Variable Diresidues For Targeting Nucleotides App 20150067900 - Duchateau; Philippe ;   et al. | 2015-03-05 |
Method To Overcome Dna Chemical Modifications Sensitivity Of Engineered Tale Dna Binding Domains App 20150037809 - Duchateau; Philippe ;   et al. | 2015-02-05 |
Method for modulating double-strand break-induced homologous recombination Grant 8,906,607 - Duchateau , et al. December 9, 2 | 2014-12-09 |
High Throughput Method For Assembly And Cloning Polynucleotides Comprising Highly Similar Polynucleotidic Modules App 20140309145 - Valton; Julien ;   et al. | 2014-10-16 |
Modular Base-specific Nucleic Acid Binding Domains From Burkholderia Rhizoxinica Proteins App 20140230083 - Bertonati; Claudia ;   et al. | 2014-08-14 |
I-CreI meganuclease variants with modified specificity, method of preparation and uses thereof Grant 8,715,992 - Duchateau , et al. May 6, 2 | 2014-05-06 |
New Tale-protein Scaffolds And Uses Thereof App 20140115726 - Duchateau; Philippe ;   et al. | 2014-04-24 |
Method For Increasing The Efficiency Of Double-strand Break-induced Mutagenesis App 20130337454 - Duchateau; Philippe ;   et al. | 2013-12-19 |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof Grant 8,530,214 - Arnould , et al. September 10, 2 | 2013-09-10 |
Use Of Meganucleases For Inducing Homologous Recombination Ex Vivo And In Toto In Vertebrate Somatic Tissues And Application Thereof App 20130203840 - ARNOULD; Sylvain ;   et al. | 2013-08-08 |
Method For Improving Cleavage Of Dna By Endonuclease Sensitive To Methylation App 20130196320 - Duchateau; Philippe ;   et al. | 2013-08-01 |
Method For Modulating Double-strand Break-induced Homologous Recombination App 20130190385 - Duchateau; Philippe ;   et al. | 2013-07-25 |
I-crei Variants With New Specificity And Methods Of Their Generation App 20130149786 - Duchateau; Philippe ;   et al. | 2013-06-13 |
Method For The Generation Of Compact Tale-nucleases And Uses Thereof App 20130117869 - DUCHATEAU; PHILIPPE ;   et al. | 2013-05-09 |
Use Of Meganucleases For Inducing Homologous Recombination Ex Vivo And In Toto In Vertebrate Somatic Tissues And Application Thereof App 20120288942 - Arnould; Sylvain ;   et al. | 2012-11-15 |
Use Of Meganucleases For Inducing Homologous Recombination Ex Vivo And In Toto In Vertebrate Somatic Tissues And Application Thereof App 20120288943 - Arnould; Sylvain ;   et al. | 2012-11-15 |
I-crei Meganuclease Variants With Modified Specificity, Method Of Preparation And Uses Thereof App 20120258537 - DUCHATEAU; Philippe ;   et al. | 2012-10-11 |
Method For Modulating The Efficiency Of Double-strand Break-induced Mutagenesis App 20120244131 - Delacote; Fabien ;   et al. | 2012-09-27 |
Custom-made Meganuclease And Use Thereof App 20120159659 - Arnould; Sylvain ;   et al. | 2012-06-21 |
Use Of Meganucleases For Inducing Homologous Recombination Ex Vivo And In Toto In Vertebrate Somatic Tissues And Application Thereof App 20110287513 - Arnould; Sylvain ;   et al. | 2011-11-24 |
Novel Method To Generate Meganucleases With Altered Characteristics App 20110207199 - Paques; Frederic ;   et al. | 2011-08-25 |
Chimeric Meganuclease Enzymes And Uses Thereof App 20110173710 - Grizot; Sylvestre ;   et al. | 2011-07-14 |
Heterodimeric Meganucleases and Use Thereof App 20110158974 - Duchateau; Philippe ;   et al. | 2011-06-30 |
Use Of Meganucleases For Inducing Homologous Recombination Ex Vivo And In Toto In Vertebrate Somatic Tissues And Application Thereof App 20110151539 - Arnould; Sylvain ;   et al. | 2011-06-23 |
I-crei Meganuclease Variants With Modified Specificity, Method Of Preparation And Uses Thereof App 20110072527 - DUCHATEAU; Philippe ;   et al. | 2011-03-24 |
I-CreI meganuclease variants with modified specificity, method of preparation and uses thereof Grant 7,897,372 - Duchateau , et al. March 1, 2 | 2011-03-01 |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof Grant 7,842,489 - Arnould , et al. November 30, 2 | 2010-11-30 |
Use Of Meganucleases For Inducing Homologous Recombination Ex Vivo And In Toto In Vertebrate Somatic Tissues And Application Thereof App 20100144012 - ARNOULD; Sylvain ;   et al. | 2010-06-10 |
I-crei Meganuclease Variants With Modified Specificity, Method Of Preparation And Uses Thereof App 20100021448 - Duchateau; Philippe ;   et al. | 2010-01-28 |
Custom-made meganuclease and use thereof App 20060206949 - Arnould; Sylvain ;   et al. | 2006-09-14 |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof App 20060153826 - Arnould; Sylvain ;   et al. | 2006-07-13 |