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Substituted Nucleosides, Nucleotides And Analogs Thereof App 20210139523 - BEIGELMAN; Leonid ;   et al. | 2021-05-13 |
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RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 10,889,815 - Beigelman , et al. January 12, 2 | 2021-01-12 |
S-antigen Transport Inhibiting Oligonucleotide Polymers And Methods App 20200405743 - Beigelman; Leonid ;   et al. | 2020-12-31 |
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Substituted Nucleosides, Nucleotides And Analaogs Thereof App 20200277321 - BEIGELMAN; Leonid ;   et al. | 2020-09-03 |
Substituted nucleosides, nucleotides and analogs thereof Grant RE48,171 - Wang , et al. A | 2020-08-25 |
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AZA-pyridone compounds and uses thereof Grant 10,702,523 - Hendricks , et al. | 2020-07-07 |
Substituted nucleosides, nucleotides and analogs thereof Grant 10,696,708 - Dyatkina , et al. June 30, 2 | 2020-06-30 |
Substituted nucleosides, nucleotides and analogs thereof Grant 10,683,320 - Beigelman , et al. | 2020-06-16 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 10,662,428 - Beigelman , et al. | 2020-05-26 |
S-antigen Transport Inhibiting Oligonucleotide Polymers And Methods App 20200147124 - Beigelman; Leonid ;   et al. | 2020-05-14 |
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Cyclic Dinucleotides As Sting Agonists App 20190375781 - Emanuel; Stuart ;   et al. | 2019-12-12 |
Substituted nucleosides, nucleotides and analogs thereof Grant 10,487,104 - Beigelman , et al. Nov | 2019-11-26 |
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Aza-pyridone Compounds And Uses Thereof App 20190314373 - HENDRICKS; Robert Than ;   et al. | 2019-10-17 |
Substituted nucleosides, nucleotides and analogs thereof Grant 10421771 - | 2019-09-24 |
Substituted nucleosides, nucleotides and analogs thereof Grant 10420788 - | 2019-09-24 |
Antiviral Compounds App 20190263754 - WANG; Guangyi ;   et al. | 2019-08-29 |
Substituted nucleosides, nucleotides and analogs thereof Grant 10,370,401 - Beigelman , et al. | 2019-08-06 |
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Pyridazinone compounds and uses thereof Grant 10,364,226 - Beigelman , et al. | 2019-07-30 |
Antiviral compounds Grant 10,358,453 - Wang , et al. July 23, 2 | 2019-07-23 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 10,351,852 - McSwiggen , et al. July 16, 2 | 2019-07-16 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20190194658 - Beigelman; Leonid ;   et al. | 2019-06-27 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20190169221 - WANG; Guangyi ;   et al. | 2019-06-06 |
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Aza-pyridone compounds and uses thereof Grant 10,251,882 - Hendricks , et al. | 2019-04-09 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20190085011 - Beigelman; Leonid ;   et al. | 2019-03-21 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20190062746 - Beigelman; Leonid ;   et al. | 2019-02-28 |
Acyclic Antivirals App 20190055273 - BEIGELMAN; Leonid ;   et al. | 2019-02-21 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20190054108 - Blatt; Lawrence M. ;   et al. | 2019-02-21 |
Aza-pyridone compounds and uses thereof Grant 10,208,045 - Hendricks , et al. Feb | 2019-02-19 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20190031703 - Beigelman; Leonid ;   et al. | 2019-01-31 |
Method of preparing AZA-pyridone compounds Grant 10,183,945 - Welch , et al. Ja | 2019-01-22 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20190010497 - Beigelman; Leonid ;   et al. | 2019-01-10 |
Substituted nucleosides, nucleotides and analogs thereof Grant 10,144,755 - Beigelman , et al. De | 2018-12-04 |
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Substituted nucleosides, nucleotides and analogs thereof Grant 10,112,966 - Beigelman , et al. October 30, 2 | 2018-10-30 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20180245083 - Beigelman; Leonid ;   et al. | 2018-08-30 |
Substituted nucleosides, nucleotides and analogs thereof Grant 10,052,342 - Blatt , et al. August 21, 2 | 2018-08-21 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20180194793 - Dyatkina; Natalia ;   et al. | 2018-07-12 |
Methods Of Preparing Substituted Nucleoside Analogs App 20180186825 - Serebryany; Vladimir ;   et al. | 2018-07-05 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 10,000,754 - Beigelman , et al. June 19, 2 | 2018-06-19 |
Cyclic Dinucleotides As Sting Agonists App 20180162899 - Bignan; Gilles ;   et al. | 2018-06-14 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20180155384 - Wang; Guangyi ;   et al. | 2018-06-07 |
Modified Oligonucleotides And Methods Of Use App 20180135054 - GRYAZNOV; Sergei ;   et al. | 2018-05-17 |
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Substituted nucleosides, nucleotides and analogs thereof Grant 9,932,363 - Dyatkina , et al. April 3, 2 | 2018-04-03 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20180079774 - Beigelman; Leonid ;   et al. | 2018-03-22 |
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Methods of preparing substituted nucleoside analogs Grant 9,908,914 - Serebryany , et al. March 6, 2 | 2018-03-06 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20180044369 - Beigelman; Leonid ;   et al. | 2018-02-15 |
Substituted nucleosides, nucleotides and analogs thereof Grant 9,890,188 - Wang , et al. February 13, 2 | 2018-02-13 |
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RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20170342416 - McSwiggen; James ;   et al. | 2017-11-30 |
Substituted nucleosides, nucleotides and analogs thereof Grant 9,815,864 - Beigelman , et al. November 14, 2 | 2017-11-14 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20170298355 - Beigelman; Leonid ;   et al. | 2017-10-19 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20170283816 - Beigelman; Leonid ;   et al. | 2017-10-05 |
Compounds For The Treatment Of Paramyxovirus Viral Infections App 20170283429 - Wang; Guangyi ;   et al. | 2017-10-05 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,771,588 - McSwiggen , et al. September 26, 2 | 2017-09-26 |
Method Of Preparing Aza-pyridone Compounds App 20170260189 - WELCH; Michael Hunter ;   et al. | 2017-09-14 |
Substituted nucleosides, nucleotides and analogs thereof Grant 9,758,544 - Beigelman , et al. September 12, 2 | 2017-09-12 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,738,899 - Beigelman , et al. August 22, 2 | 2017-08-22 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,732,344 - Beigelman , et al. August 15, 2 | 2017-08-15 |
Compounds for the treatment of paramoxyvirus viral infections Grant 9,724,351 - Wang , et al. August 8, 2 | 2017-08-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20170211083 - Beigelman; Leonid ;   et al. | 2017-07-27 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20170143751 - Blatt; Lawrence M. ;   et al. | 2017-05-25 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20170143749 - Blatt; Lawrence M. ;   et al. | 2017-05-25 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,657,294 - Beigelman , et al. May 23, 2 | 2017-05-23 |
Substituted nucleosides, nucleotides and analogs thereof Grant 9,603,864 - Blatt , et al. March 28, 2 | 2017-03-28 |
Substituted nucleosides, nucleotides and analogs thereof Grant 9,603,863 - Blatt , et al. March 28, 2 | 2017-03-28 |
Substituted nucleotide analogs Grant 9,605,018 - Wang , et al. March 28, 2 | 2017-03-28 |
Substituted nucleosides, nucleotides and analogs thereof Grant 9,598,457 - Smith , et al. March 21, 2 | 2017-03-21 |
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Cyclic Nucleotide Analogs App 20170002037 - Beigelman; Leonid ;   et al. | 2017-01-05 |
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Azido Nucleosides And Nucleotide Analogs App 20160264610 - Beigelman; Leonid ;   et al. | 2016-09-15 |
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Substituted nucleosides, nucleotides and analogs thereof Grant 9,422,322 - Dyatkina , et al. August 23, 2 | 2016-08-23 |
Aza-pyridone Compounds And Uses Thereof App 20160228438 - Hendricks; Robert Than ;   et al. | 2016-08-11 |
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Substituted Nucleosides, Nucleotides And Analogs Thereof App 20160039861 - Smith; David Bernard ;   et al. | 2016-02-11 |
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Substituted Nucleosides, Nucleotides And Analogs Thereof App 20160024136 - Beigelman; Leonid ;   et al. | 2016-01-28 |
Substituted nucleosides, nucleotides and analogs thereof Grant 9,243,022 - Beigelman , et al. January 26, 2 | 2016-01-26 |
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Compounds For The Treatment Of Paramoxyvirus Viral Infections App 20150238498 - Wang; Guangyi ;   et al. | 2015-08-27 |
Substituted nucleosides, nucleotides and analogs thereof Grant 9,073,960 - Beigelman , et al. July 7, 2 | 2015-07-07 |
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Antiviral Compounds App 20150065504 - Wang; Guangyi ;   et al. | 2015-03-05 |
Compounds and methods for treating inflammatory and fibrotic disorders Grant 8,969,347 - Kossen , et al. March 3, 2 | 2015-03-03 |
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Methods of preparing substituted nucleotide analogs Grant 8,895,723 - Serebryany , et al. November 25, 2 | 2014-11-25 |
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Substituted nucleotide analogs Grant 8,871,737 - Smith , et al. October 28, 2 | 2014-10-28 |
Cyclic Nucleotide Analogs App 20140303108 - Beigelman; Leonid ;   et al. | 2014-10-09 |
Methods of preparing substituted nucleotide analogs Grant 8,846,896 - Serebryany , et al. September 30, 2 | 2014-09-30 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 8,846,894 - McSwiggen , et al. September 30, 2 | 2014-09-30 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20140288148 - Beigelman; Leonid ;   et al. | 2014-09-25 |
Cyclic nucleotide analogs Grant 8,772,474 - Beigelman , et al. July 8, 2 | 2014-07-08 |
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Method of modulating stress-activated protein kinase system Grant 8,741,936 - Blatt , et al. June 3, 2 | 2014-06-03 |
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RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 08618277 - | 2013-12-31 |
Double-stranded RNA directed to CASP2 and methods of use thereof Grant 8,614,309 - Feinstein , et al. December 24, 2 | 2013-12-24 |
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Substituted Nucleotide Analogs App 20130164261 - Wang; Guangyi ;   et al. | 2013-06-27 |
Substituted Nucleosides, Nucleotides And Analogs Thereof App 20130165400 - Beigelman; Leonid ;   et al. | 2013-06-27 |
Conjugates and compositions for cellular delivery Grant 8,461,313 - Matulic-Adamic , et al. June 11, 2 | 2013-06-11 |
Novel Sirna Structures App 20130123334 - Feinstein; Elena ;   et al. | 2013-05-16 |
Compounds And Methods For Treating Inflammatory And Fibrotic Disorders App 20130102597 - Kossen; Karl ;   et al. | 2013-04-25 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20130018082 - McSwigen; James ;   et al. | 2013-01-17 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20130012567 - McSwigen; James ;   et al. | 2013-01-10 |
Compounds and methods for treating inflammatory and fibrotic disorders Grant 8,304,413 - Kossen , et al. November 6, 2 | 2012-11-06 |
Method Of Modulating Stress-activated Protein Kinase System App 20120258924 - Blatt; Lawrence M. ;   et al. | 2012-10-11 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SINA) Grant 8,273,866 - McSwiggen , et al. September 25, 2 | 2012-09-25 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 8,268,986 - Beigelman , et al. September 18, 2 | 2012-09-18 |
RNA interference mediated inhibition of respiratory syncytial virus (RSV) expression using short interfering nucleic acid (siNA) Grant 8,258,288 - McSwiggen , et al. September 4, 2 | 2012-09-04 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 8,242,257 - Beigelman , et al. August 14, 2 | 2012-08-14 |
Conjugates and Compositions for Cellular Delivery App 20120202983 - Matulic-Adamic; Jasenka ;   et al. | 2012-08-09 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 8,236,944 - Beigelman , et al. August 7, 2 | 2012-08-07 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 8,232,383 - McSwiggen , et al. July 31, 2 | 2012-07-31 |
Cyclic Nucleotide Analogs App 20120165286 - Beigelman; Leonid ;   et al. | 2012-06-28 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid Grant 8,202,979 - McSwiggen , et al. June 19, 2 | 2012-06-19 |
Conjugates and compositions for cellular delivery Grant 8,188,247 - Beigelman , et al. May 29, 2 | 2012-05-29 |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA) Grant 8,153,778 - McSwiggen , et al. April 10, 2 | 2012-04-10 |
Substituted Nucleotide Analogs App 20120071434 - Smith; David Bernard ;   et al. | 2012-03-22 |
Substituted Nucleotide Analogs App 20120070411 - Beigelman; Leonid ;   et al. | 2012-03-22 |
Azido Nucleosides And Nucleotide Analogs App 20120070415 - Beigelman; Leonid ;   et al. | 2012-03-22 |
Compounds and methods for inhibiting hepatitis C viral replication Grant 8,119,592 - Beigelman , et al. February 21, 2 | 2012-02-21 |
RNA INTERFERENCE MEDIATED INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20120041184 - Beigelman; Leonid ;   et al. | 2012-02-16 |
RNA INTERFERENCE MEDIATED INHIBITION OF TNF AND TNF RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20120004403 - BEIGELMAN; LEONID ;   et al. | 2012-01-05 |
RNA INTERFERENCE MEDIATED INHIBITION OF PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9 (PCSK9) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20110313024 - BEIGELMAN; LEONID ;   et al. | 2011-12-22 |
RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA) Grant 8,076,472 - McSwiggen , et al. December 13, 2 | 2011-12-13 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20110301219 - Beigelman; Leonid ;   et al. | 2011-12-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20110301220 - Beigelman; Leonid ;   et al. | 2011-12-08 |
RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA) Grant 8,067,575 - McSwiggen , et al. November 29, 2 | 2011-11-29 |
Macrocyclic inhibitors of hepatitis C virus replication Grant 8,048,862 - Seiwert , et al. November 1, 2 | 2011-11-01 |
RNA Interference Mediated Inhibition of Gene Expression Using Chemically Modified Short Interfering Nucleic Acid (siNA) App 20110263683 - Beigelman; Leonid ;   et al. | 2011-10-27 |
RNA interference mediated inhibition of Stearoyl-CoA desaturase (SCD) gene expression using short interfering nucelic acid (siNA) Grant 8,017,761 - McSwiggen , et al. September 13, 2 | 2011-09-13 |
RNA interference mediated treatment of alzheimer's disease using short interfering nucleic acid (siNA) Grant 8,017,765 - McSwiggen , et al. September 13, 2 | 2011-09-13 |
RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA) Grant 8,013,146 - McSwiggen , et al. September 6, 2 | 2011-09-06 |
RNA interference mediated inhibition of CXCR4 gene expression using short interfering nucleic acid (siNA) Grant 8,013,143 - McSwiggen , et al. September 6, 2 | 2011-09-06 |
RNA interference mediated inhibition of TNF and TNF receptor gene expression using short interfering nucleic acid (siNA) Grant 8,008,473 - McSwiggen , et al. August 30, 2 | 2011-08-30 |
RNA interference mediated inhibition of human immunodeficiency virus (HIV) gene expression using short interfering nucleic acid (siNA) Grant 8,008,472 - McSwiggen , et al. August 30, 2 | 2011-08-30 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 7,989,612 - McSwiggen , et al. August 2, 2 | 2011-08-02 |
RNA interference mediated inhibition of platelet derived growth factor (PDGF) and platelet derived growth factor receptor (PDGFR) gene expression using short interfering nucleic acid (siNA) Grant 7,985,853 - McSwiggen , et al. July 26, 2 | 2011-07-26 |
RNA interference mediated inhibition of myostatin gene expression using short interfering nucleic acid (siNA) Grant 7,977,472 - Beigelman , et al. July 12, 2 | 2011-07-12 |
RNA Interference Mediated Inhibition of Vascular Cell Adhesion Molecule (VCAM) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20110160281 - McSwiggen; James ;   et al. | 2011-06-30 |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acid (siNA) Grant 7,956,178 - McSwiggen , et al. June 7, 2 | 2011-06-07 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 7,956,176 - McSwiggen , et al. June 7, 2 | 2011-06-07 |
RNA interference mediated inhibition of intercellular adhesion molecule (ICAM) gene expression using short interfering nucleic acid (siNA) Grant 7,943,757 - McSwiggen , et al. May 17, 2 | 2011-05-17 |
Novel Sirna Structures App 20110112168 - Feinstein; Elena ;   et al. | 2011-05-12 |
Novel Inhibitors of Hepatitis C Virus Replication App 20110110890 - Beigelman; Leonid ;   et al. | 2011-05-12 |
Peptide inhibitors of hepatitis C virus replication Grant 7,932,277 - Seiwert , et al. April 26, 2 | 2011-04-26 |
RNA interference mediated inhibition of polycomb group protein EZH2 gene expression using short interfering nucleic acid (siNA) Grant 7,928,218 - McSwiggen , et al. April 19, 2 | 2011-04-19 |
RNA interference mediated inhibition of placental growth factor gene expression using short interfering nucleic acid (SINA) Grant 7,928,219 - McSwiggen , et al. April 19, 2 | 2011-04-19 |
RNA interference mediated inhibition of stromal cell-derived factor-1 (SDF-1) gene expression using short interfering nucleic acid (siNA) Grant 7,928,220 - McSwiggen , et al. April 19, 2 | 2011-04-19 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 7,923,547 - McSwiggen , et al. April 12, 2 | 2011-04-12 |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA) Grant 7,923,549 - McSwiggen , et al. April 12, 2 | 2011-04-12 |
Therapeutic Antiviral Peptides App 20110082182 - Buckman; Brad ;   et al. | 2011-04-07 |
Novel Macrocyclic Inhibitors Of Hepatitis C Virus Replication App 20110081315 - Buckman; Brad ;   et al. | 2011-04-07 |
RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA) Grant 7,915,400 - McSwiggen , et al. March 29, 2 | 2011-03-29 |
RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA) Grant 7,910,724 - McSwiggen , et al. March 22, 2 | 2011-03-22 |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA) Grant 7,910,725 - McSwiggen , et al. March 22, 2 | 2011-03-22 |
Novel Macrocyclic Inhibitors Of Hepatitis C Virus Replication App 20110059047 - Seiwert; Scott D. ;   et al. | 2011-03-10 |
RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering nucleic acid (siNA) Grant 7,897,756 - McSwiggen , et al. March 1, 2 | 2011-03-01 |
RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA) Grant 7,897,755 - McSwiggen , et al. March 1, 2 | 2011-03-01 |
RNA interference mediated inhibition of XIAP gene expression using short interfering nucleic acid (siNA) Grant 7,897,753 - McSwiggen , et al. March 1, 2 | 2011-03-01 |
RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA) Grant 7,897,752 - McSwiggen , et al. March 1, 2 | 2011-03-01 |
RNA interference mediated inhibition of protein tyrosine phosphatase-1B (PTP-1B) gene expression using short interfering nucleic acid (siNA) Grant 7,897,757 - Beigelman , et al. March 1, 2 | 2011-03-01 |
RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA) Grant 7,893,248 - McSwiggen , et al. February 22, 2 | 2011-02-22 |
RNA INTERFERENCE MEDIATED INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20110015251 - MCSWIGGEN; JAMES ;   et al. | 2011-01-20 |
Conjugates And Compositions For Cellular Delivery App 20100331535 - MATULIC-ADAMIC; JASENKA ;   et al. | 2010-12-30 |
2-5a Analogs And Their Methods Of Use App 20100331397 - Beigelman; Leonid ;   et al. | 2010-12-30 |
RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA) Grant 7,858,771 - McSwiggen , et al. December 28, 2 | 2010-12-28 |
Conjugates and compositions for cellular delivery Grant 7,858,625 - Matulic-Adamic , et al. December 28, 2 | 2010-12-28 |
RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA) Grant 7,855,284 - McSwiggen , et al. December 21, 2 | 2010-12-21 |
RNA INTERFERENCE MEDIATED INHIBITION OF PLATELET DERIVED GROWTH FACTOR (PDGF) AND PLATELET DERIVED GROWTH FACTOR RECEPTOR (PDGFR) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100317717 - MCSWIGGEN; JAMES ;   et al. | 2010-12-16 |
RNA INTERFERENCE MEDIATED INHIBITION OF TNF AND TNF RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100317716 - MCSWIGGEN; JAMES ;   et al. | 2010-12-16 |
RNA INTERFERENCE MEDIATED INHIBITION OF INTERCELLULAR ADHESION MOLECULE (ICAM) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100311812 - McSwiggen; James ;   et al. | 2010-12-09 |
Rna Interference Mediated Inhibition Of Adenosine A1 Receptor (adora1) Gene Expression Using Short Interfering Rna App 20100305191 - McSwiggen; James ;   et al. | 2010-12-02 |
Substituted Nucleoside And Nucleotide Analogs App 20100249068 - Beigelman; Leonid ;   et al. | 2010-09-30 |
Method Of Modulating Stress-activated Protein Kinase System App 20100240704 - Blatt; Lawrence M. ;   et al. | 2010-09-23 |
RNA Interference Mediated Inhibition of Gene Expression Using Chemically Modified Short Interfering Nucleic Acid (siNA) App 20100240730 - BEIGELMAN; LEONID ;   et al. | 2010-09-23 |
Protected Nucleotide Analogs App 20100240604 - Beigelman; Leonid ;   et al. | 2010-09-23 |
RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA) Grant 7,795,422 - McSwiggen , et al. September 14, 2 | 2010-09-14 |
RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100228018 - McSwiggen; James ;   et al. | 2010-09-09 |
RNA INTERFERENCE MEDIATED INHIBITION OF MYOSTATIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100227912 - McSwiggen; James ;   et al. | 2010-09-09 |
RNA INTERFERENCE MEDIATED INHIBITION OF CHROMOSOME TRANSLOCATION GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100227911 - McSwiggen; James ;   et al. | 2010-09-09 |
Inhibitors of hepatitis C virus replication Grant 7,781,474 - Seiwert , et al. August 24, 2 | 2010-08-24 |
Novel Inhibitors Of Hepatitis C Virus Replication App 20100209391 - SEIWERT; SCOTT ;   et al. | 2010-08-19 |
RNA Interference Mediated Inhibition of Interleukin and Interleukin Receptor Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100184824 - McSwiggen; James ;   et al. | 2010-07-22 |
RNA Interference Mediated Inhibition of Protein Tyrosine Phosphatase-1B (PTP-1B) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100184825 - MCSWIGGEN; JAMES ;   et al. | 2010-07-22 |
RNA INTERFERENCE MEDIATED INHIBITION OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100173976 - McSwiggen; James ;   et al. | 2010-07-08 |
RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100168208 - McSwiggen; James ;   et al. | 2010-07-01 |
RNA Interference Mediated Inhibition of Platelet-Derived Endothelial Cell Growth Factor (ECGF1) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100144851 - McSwiggen; James ;   et al. | 2010-06-10 |
RNA Interference Mediated Inhibition of NOGO and NOGO Receptor Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100144842 - McSwiggen; James ;   et al. | 2010-06-10 |
Method of modulating stress-activated protein kinase system Grant 7,728,013 - Blatt , et al. June 1, 2 | 2010-06-01 |
RNA Interference Mediated Inhibition of GRB2 Associated Binding Protein (GAB2) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100130592 - MCSWIGGEN; JAMES ;   et al. | 2010-05-27 |
Therapeutic Antiviral Peptides App 20100119479 - BUCKMAN; BRAD ;   et al. | 2010-05-13 |
RNA Interference Mediated Inhibition of Interleukin and Interleukin Receptor Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100113564 - McSwiggen; James ;   et al. | 2010-05-06 |
RNA INTERFERENCE MEDIATED INHIBITION OF MATRIX METALLOPROTEINASE 13 (MMP13) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100099744 - McSwiggen; James ;   et al. | 2010-04-22 |
RNA INTERFERENCE MEDIATED INHIBITION OF CHECKPOINT KINASE-1 (CHK-1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100099743 - McSwiggen; James ;   et al. | 2010-04-22 |
RNA INTERFERENCE MEDIATED INHIBITION OF MUSCARINIC COLINERGIC RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100099750 - McSwiggen; James ;   et al. | 2010-04-22 |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA) Grant 7,700,760 - McSwiggen , et al. April 20, 2 | 2010-04-20 |
RNA INTERFERENCE MEDIATED INHIBITION OF MYC AND/OR MYB GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100093835 - McSwiggen; James ;   et al. | 2010-04-15 |
RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering nucleic acid (siNA) Grant 7,691,999 - McSwiggen , et al. April 6, 2 | 2010-04-06 |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA) Grant 7,683,166 - McSwiggen , et al. March 23, 2 | 2010-03-23 |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA) Grant 7,683,165 - McSwiggen , et al. March 23, 2 | 2010-03-23 |
RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA) Grant 7,678,897 - McSwiggen , et al. March 16, 2 | 2010-03-16 |
RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA) Grant 7,667,029 - McSwiggen , et al. February 23, 2 | 2010-02-23 |
RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA) Grant 7,667,030 - McSwiggen , et al. February 23, 2 | 2010-02-23 |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acid (siNA) Grant 7,662,952 - McSwiggen , et al. February 16, 2 | 2010-02-16 |
RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA) Grant 7,662,951 - McSwiggen , et al. February 16, 2 | 2010-02-16 |
Novel Compositions for the Delivery of Negatively Charged Molecules App 20100036115 - Beigelman; Leonid ;   et al. | 2010-02-11 |
RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA) Grant 7,659,390 - McSwiggen , et al. February 9, 2 | 2010-02-09 |
RNA interference mediated inhibition of MYC and/or MYB gene expression using short interfering nucleic acid (siNA) Grant 7,659,389 - McSwiggen , et al. February 9, 2 | 2010-02-09 |
Compounds And Methods For Treating Inflammatory And Fibrotic Disorders App 20090318455 - Kossen; Karl ;   et al. | 2009-12-24 |
RNA INTERFERENCE MEDIATED INHIBITION OF MAP KINASE GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090306182 - McSwiggen; James ;   et al. | 2009-12-10 |
Novel Peptide Inhibitors Of Hepatitis C Virus Replication App 20090297476 - SEIWERT; SCOTT ;   et al. | 2009-12-03 |
RNA INTERFERENCE MEDIATED INHIBITION OF RESPIRATORY SYNCYTIAL VIRUS (RSV) EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090281164 - McSwiggen; James ;   et al. | 2009-11-12 |
Novel Macrocyclic Inhibitors Of Hepatitis C Virus Replication App 20090269305 - Seiwert; Scott D. ;   et al. | 2009-10-29 |
RNA INTERFERENCE MEDIATED INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090264504 - McSwiggen; James ;   et al. | 2009-10-22 |
Novel Inhibitors of Hepatitis C Virus Replication App 20090257979 - Beigelman; Leonid ;   et al. | 2009-10-15 |
RNA INTERFERENCE MEDIATED INHIBITION OF CXCR4 GENE EXPRESSION USING SHORT INTERFERING NUCELEIC ACID (siNA) App 20090253772 - McSwiggen; James ;   et al. | 2009-10-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF TNF AND TNF RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090253773 - McSwiggen; James ;   et al. | 2009-10-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF PLATELET DERIVED GROWTH FACTOR (PDGF) AND PLATELET DERIVED GROWTH FACTOR RECEPTOR (PDGFR) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090253774 - McSwiggen; James ;   et al. | 2009-10-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF B-CELL CLL/LYMPHOMA-2 (BCL2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090247613 - McSwiggen; James ;   et al. | 2009-10-01 |
RNA Interference Mediated Inhibition of Adenosine A1 Receptor (ADORA1) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20090247606 - McSwiggen; James ;   et al. | 2009-10-01 |
RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN TYROSINE PHOSPHATASE-1B (PTP-1B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090239931 - McSwiggen; James ;   et al. | 2009-09-24 |
2' Deoxy-2'-Alkylnucleotide Containing Nucleic Acid App 20090221807 - Usman; Nassim ;   et al. | 2009-09-03 |
RNA INTERFERENCE MEDIATED INHIBITION OF INTERCELLULAR ADHESION MOLECULE (ICAM) GENE EXPRESSION USING SHORT INTERFERING NUCELIC ACID (siNA) App 20090192105 - McSwiggen; James ;   et al. | 2009-07-30 |
RNA INTERFERENCE MEDIATED INHIBITION OF HYPOXIA INDUCIBLE FACTOR 1 (HIF1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090192104 - McSwiggen; James ;   et al. | 2009-07-30 |
2-5a Analogs And Their Methods Of Use App 20090181921 - Blatt; Lawrence ;   et al. | 2009-07-16 |
Chemically Modified Short Interfering Nucleic Acid Molecules That Mediate Rna Interference App 20090176725 - Morrissey; David ;   et al. | 2009-07-09 |
Protected Nucleotide Analogs App 20090176732 - Beigelman; Leonid ;   et al. | 2009-07-09 |
Compositions for the delivery of negatively charged molecules Grant 7,553,830 - Beigelman , et al. June 30, 2 | 2009-06-30 |
RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS C VIRUS (HCV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090156528 - McSwiggen; James ;   et al. | 2009-06-18 |
RNA INTERFERENCE MEDIATED INHIBITION OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090156533 - McSwiggen; James ;   et al. | 2009-06-18 |
Novel Macrocyclic Inhibitors Of Hepatitis C Virus Replication App 20090155209 - BLATT; LAWRENCE M. ;   et al. | 2009-06-18 |
RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090149407 - McSwiggen; James ;   et al. | 2009-06-11 |
RNA INTERFERENCE MEDIATED INHIBITION OF TELOMERASE GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090149408 - McSwiggen; James ;   et al. | 2009-06-11 |
RNA INTERFERENCE MEDIATED INHIBITION OF INTERLEUKIN AND INTERLEUKIN RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090143324 - McSwiggen; James ;   et al. | 2009-06-04 |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) Grant 7,176,304 - McSwiggen , et al. February 13, 2 | 2007-02-13 |
Conjugates and compositions for cellular delivery Grant 7,109,165 - Matulic-Adamic , et al. September 19, 2 | 2006-09-19 |
Antibodies having specificity for 2'-C-allyl nucleic acids Grant 7,071,311 - Radka , et al. July 4, 2 | 2006-07-04 |
Synthesis, deprotection, analysis and purification of RNA and ribozymes Grant 7,041,817 - Usman , et al. May 9, 2 | 2006-05-09 |
Chemical synthesis of methoxy nucleosides Grant 6,972,330 - Beigelman , et al. December 6, 2 | 2005-12-06 |
Non-nucleotide containing RNA Grant 6,849,726 - Usman , et al. February 1, 2 | 2005-02-01 |
Nucleic acid catalysts with endonuclease activity Grant 6,831,171 - Breaker , et al. December 14, 2 | 2004-12-14 |
2'-O-alkylthioalkyl and 2'-C-alkylthioalkyl-containing nucleic acids Grant 6,818,759 - Beigelman , et al. November 16, 2 | 2004-11-16 |
Xylofuranosly-containing nucleoside phosphoramidites and polynucleotides Grant 6,797,815 - Matulic-Adamic , et al. September 28, 2 | 2004-09-28 |
Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives Grant 6,686,463 - Beigelman , et al. February 3, 2 | 2004-02-03 |
Nucleic acid molecules with novel chemical compositions capable of modulating gene expression Grant 6,673,611 - Thompson , et al. January 6, 2 | 2004-01-06 |
Nucleic acid catalysts with endonuclease activity Grant 6,656,731 - Eckstein , et al. December 2, 2 | 2003-12-02 |
Synthesis, deprotection, analysis and purification of RNA and ribozymes Grant 6,649,751 - Usman , et al. November 18, 2 | 2003-11-18 |
Oligoribonucleotides with enzymatic activity Grant 6,617,438 - Beigelman , et al. September 9, 2 | 2003-09-09 |
Nucleic acid catalysts comprising L-nucleotide analogs Grant 6,602,858 - Beigelman August 5, 2 | 2003-08-05 |
Enzymatic nucleic acids containing 5'-and or 3'-cap structures Grant 6,586,238 - Matulic-Adamic , et al. July 1, 2 | 2003-07-01 |
Synthetic ribonucleic acids with RNAse activity Grant 6,528,640 - Beigelman , et al. March 4, 2 | 2003-03-04 |
Nucleoside triphosphates and their incorporation into oligonucleotides Grant 6,509,460 - Beigelman , et al. January 21, 2 | 2003-01-21 |
Nucleoside triphosphates and their incorporation into oligonucleotides Grant 6,482,932 - Beigelman , et al. November 19, 2 | 2002-11-19 |
Synthesis, deprotection, analysis and purification of RNA and ribozymes Grant 6,469,158 - Usman , et al. October 22, 2 | 2002-10-22 |
Synthesis, deprotection, analysis and purification for RNA and ribozymes Grant 6,437,117 - Usman , et al. August 20, 2 | 2002-08-20 |
Compositions for the delivery of negatively charged molecules Grant 6,395,713 - Beigelman , et al. May 28, 2 | 2002-05-28 |
Amido and peptido modified catalytic oligonucleotides Grant 6,379,954 - Dudycz , et al. April 30, 2 | 2002-04-30 |
2'-deoxy-2'-alkylnucleotide containing nucleic acid Grant 6,365,374 - Usman , et al. April 2, 2 | 2002-04-02 |
Non-nucleotide containing nucleic acid Grant 6,362,323 - Usman , et al. March 26, 2 | 2002-03-26 |
Xylofuranosly-containing nucleoside phosphoramidites and polynucleotides Grant 6,316,612 - Matulic-Adamic , et al. November 13, 2 | 2001-11-13 |
Nucleic acid catalysts comprising L-nucleotide analogs Grant 6,251,666 - Beigelman June 26, 2 | 2001-06-26 |
Nucleoside analogs Grant 6,248,878 - Matulic-Adamic , et al. June 19, 2 | 2001-06-19 |
2'-O-alkylthioalkyl and 2'-c-alkylthioalkyl-containing nucleic acids Grant 6,239,272 - Beigelman , et al. May 29, 2 | 2001-05-29 |
2'-O-amino-containing nucleoside analogs and polynucleotides Grant 6,159,951 - Karpeisky , et al. December 12, 2 | 2000-12-12 |
Nucleoside triphosphates and their incorporation into oligonucleotides Grant 6,127,535 - Beigelman , et al. October 3, 2 | 2000-10-03 |
Non-nucleotide containing enzymatic nucleic acid Grant 6,117,657 - Usman , et al. September 12, 2 | 2000-09-12 |
Amido and peptido modified enzymatic nucleic acid molecules Grant 6,093,555 - Dudycz , et al. July 25, 2 | 2000-07-25 |
Enzymatic nucleic acids containing 5'-and/or 3'-cap structures Grant 5,998,203 - Matulic-Adamic , et al. December 7, 1 | 1999-12-07 |
2'-deoxy-2'-alkylnucleotide containing nucleic acid Grant 5,985,621 - Usman , et al. November 16, 1 | 1999-11-16 |
Chemical syntheses of 2'-O-methoxy purine nucleosides Grant 5,962,675 - Beigelman , et al. October 5, 1 | 1999-10-05 |
Non-nucleotide containing enzymatic nucleic acid Grant 5,891,683 - Usman , et al. April 6, 1 | 1999-04-06 |
Base-modified enzymatic nucleic acid Grant 5,891,684 - Usman , et al. April 6, 1 | 1999-04-06 |
Base-modified enzymatic nucleic acid Grant 5,879,938 - Usman , et al. March 9, 1 | 1999-03-09 |
2'-O-alkylthioalkyl and 2'-C-alkylthioalkyl-containing nucleic acids Grant 5,840,876 - Beigelman , et al. November 24, 1 | 1998-11-24 |
Amino and peptido modified enzymatic nucleic acid Grant 5,783,425 - Dudycz , et al. July 21, 1 | 1998-07-21 |
2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes) Grant 5,716,824 - Beigelman , et al. February 10, 1 | 1998-02-10 |
Base-modified enzymatic nucleic acid Grant 5,672,501 - Matulic-Adamic , et al. September 30, 1 | 1997-09-30 |
Base-modified enzymatic nucleic acid Grant 5,672,511 - Beigelman , et al. September 30, 1 | 1997-09-30 |
2'-deoxy-2'alkylnucleotide containing nucleic acid Grant 5,639,647 - Usman , et al. June 17, 1 | 1997-06-17 |
N-phthaloyl-protected 2'-amino-nucleoside phosphoramdites Grant 5,631,360 - Usman , et al. May 20, 1 | 1997-05-20 |
2'deoxy-2'-alkylnucleotide containing nucleic acid Grant 5,627,053 - Usman , et al. May 6, 1 | 1997-05-06 |