| Patent | Date |
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Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation
App 20220162603 - Allerson; Charles ; et al. | 2022-05-26 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Grant 11,078,485 - Allerson , et al. August 3, 2 | 2021-08-03 |
Compositions And Methods For Modulation Of Smn2 Splicing
App 20200181613 - Baker; Brenda F. ; et al. | 2020-06-11 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation
App 20200017855 - Allerson; Charles ; et al. | 2020-01-16 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Grant 10,266,825 - Allerson , et al. | 2019-04-23 |
Oligomeric Compounds and Compositions for use in Modulation of Small Non-Coding RNAs
App 20190062744 - Esau; Christine ; et al. | 2019-02-28 |
Compositions And Methods For Modulation Of Smn2 Splicing
App 20180291376 - Baker; Brenda F. ; et al. | 2018-10-11 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation
App 20170369880 - Allerson; Charles ; et al. | 2017-12-28 |
Phosphorous-linked oligomeric compounds and their use in gene modulation
Grant 9,771,578 - Baker , et al. September 26, 2 | 2017-09-26 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20170268002 - Esau; Christine ; et al. | 2017-09-21 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Grant 9,708,610 - Allerson , et al. July 18, 2 | 2017-07-18 |
Compositions And Methods For Modulation Of Smn2 Splicing
App 20170088835 - Baker; Brenda F. ; et al. | 2017-03-30 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20170037402 - Esau; Christine ; et al. | 2017-02-09 |
Phosphorous-linked Oligomeric Compounds And Their Use In Gene Modulation
App 20160076031 - Baker; Brenda F. ; et al. | 2016-03-17 |
Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation
App 20160053261 - Allerson; Charles ; et al. | 2016-02-25 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20160017329 - Esau; Christine ; et al. | 2016-01-21 |
Chimeric Oligomeric Compounds And Their Use In Gene Modulation
App 20160017324 - Baker; Brenda F. ; et al. | 2016-01-21 |
Compositions And Methods For Modulation Of Smn2 Splicing
App 20150353929 - Baker; Brenda F. ; et al. | 2015-12-10 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Grant 9,150,605 - Allerson , et al. October 6, 2 | 2015-10-06 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Grant 9,150,606 - Allerson , et al. October 6, 2 | 2015-10-06 |
Compositions and methods for modulation of SMN2 splicing
Grant 8,946,183 - Baker , et al. February 3, 2 | 2015-02-03 |
Chimeric Oligomeric Compounds Comprising Alternating Regions Of Northern And Southern Conformational Geometry
App 20140357856 - Monia; Brett P. ; et al. | 2014-12-04 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20140336370 - Esau; Christine ; et al. | 2014-11-13 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20140329882 - Esau; Christine ; et al. | 2014-11-06 |
Method of inhibiting miR-33 using a modified oligonucleotide
Grant 8,809,294 - Esau , et al. August 19, 2 | 2014-08-19 |
Chimeric oligomeric compounds comprising alternating regions of northern and southern conformational geometry
Grant 8,791,083 - Monia , et al. July 29, 2 | 2014-07-29 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20140121364 - Esau; Christine ; et al. | 2014-05-01 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20140121365 - Esau; Christine ; et al. | 2014-05-01 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20140057963 - Esau; Christine ; et al. | 2014-02-27 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
Grant 8,604,183 - Allerson , et al. December 10, 2 | 2013-12-10 |
Double stranded constructs comprising one or more short strands hybridized to a longer strand
Grant 8,569,474 - Baker , et al. October 29, 2 | 2013-10-29 |
Compositions And Methods For Modulation Of Smn2 Splicing
App 20130109091 - Baker; Brenda F. ; et al. | 2013-05-02 |
Compositions and methods for modulation of SMN2 splicing
Grant 8,361,977 - Baker , et al. January 29, 2 | 2013-01-29 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20120283319 - Esau; Christine ; et al. | 2012-11-08 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20120157514 - Esau; Christine ; et al. | 2012-06-21 |
Compositions And Methods For Modulation Of Smn2 Splicing
App 20120149757 - Krainer; Adrian R. ; et al. | 2012-06-14 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-coding Rnas
App 20120122216 - Esau; Christine ; et al. | 2012-05-17 |
Nuclease-based method for detecting and quantitating oligonucleotides
Grant 8,163,477 - Yu , et al. April 24, 2 | 2012-04-24 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
App 20110224277 - Esau; Christine ; et al. | 2011-09-15 |
Conjugates For Use In Hepatocyte Free Uptake Assays
App 20110171730 - Bennett; C. Frank ; et al. | 2011-07-14 |
2'-substituted oligomeric compounds and compositions for use in gene modulations
Grant 7,919,612 - Baker , et al. April 5, 2 | 2011-04-05 |
Conjugates for use in hepatocyte free uptake assays
Grant 7,884,086 - Bennett , et al. February 8, 2 | 2011-02-08 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
App 20100267813 - Esau; Christine ; et al. | 2010-10-21 |
2'-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
Grant 7,812,149 - Prakash , et al. October 12, 2 | 2010-10-12 |
Double stranded compositions comprising a 3'-endo modified strand for use in gene modulation
Grant 7,790,691 - Kraynack , et al. September 7, 2 | 2010-09-07 |
Compositions And Methods For Modulation Of Smn2 Splicing
App 20100216238 - Baker; Brenda F ; et al. | 2010-08-26 |
Modulation of RANKL expression
Grant 7,700,574 - Baker , et al. April 20, 2 | 2010-04-20 |
Oligomeric compounds and compositions for use in modulation of small non-coding RNAs
Grant 7,683,036 - Esau , et al. March 23, 2 | 2010-03-23 |
Efficient Reduction Of Target Rna's By Single- And Double-stranded Oligomeric Compounds
App 20100041047 - Vickers; Timothy ; et al. | 2010-02-18 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
App 20090317907 - Esau; Christine ; et al. | 2009-12-24 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
App 20090298174 - Esau; Christine ; et al. | 2009-12-03 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
App 20090291907 - Esau; Christine ; et al. | 2009-11-26 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
App 20090291906 - Esau; Christine ; et al. | 2009-11-26 |
Oligomeric Compounds And Compositions For Use In Modulation Of Small Non-Coding RNAs
App 20090286969 - Esau; Christine ; et al. | 2009-11-19 |
Chimeric Oligomeric Compounds Comprising Alternating Regions Of Northern And Southern Conformational Geometry
App 20090258931 - Monia; Brett P. ; et al. | 2009-10-15 |
Compositions and methods for the treatment of severe acute respiratory syndrome (SARS)
Grant 7,339,051 - Crooke , et al. March 4, 2 | 2008-03-04 |
Polycyclic Sugar Surrogate-containing Oligomeric Compounds And Compositions For Use In Gene Modulation
App 20080039618 - Allerson; Charles ; et al. | 2008-02-14 |
System of components for preparing oligonucleotides
Grant 7,321,828 - Cowsert , et al. January 22, 2 | 2008-01-22 |
Double stranded compositions comprising a 3'-endo modified strand for use in gene modulation
App 20070015722 - Kraynack; Brian A. ; et al. | 2007-01-18 |
Oligomeric compounds for use in gene modulation
App 20060241072 - Baker; Brenda F. | 2006-10-26 |
Antisense modulation of CD40 ligand expression
App 20060160758 - Bennett; C. Frank ; et al. | 2006-07-20 |
Modulation of SLC26A2 expression
App 20060154885 - Bennett; C. Frank ; et al. | 2006-07-13 |
Conjugates for use in hepatocyte free uptake assays
App 20060084094 - Bennett; C. Frank ; et al. | 2006-04-20 |
Antisense modulation of matrix metalloproteinase 1 expression
App 20060074043 - Monia; Brett P. ; et al. | 2006-04-06 |
Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation
App 20060069518 - Cowsert; Lex M. ; et al. | 2006-03-30 |
Antisense modulation of p70 S6 kinase expression
App 20050267063 - Bennett, C. Frank ; et al. | 2005-12-01 |
Oligomeric compounds and compositions for use in modulation small non-coding RNAs
App 20050261218 - Esau, Christine ; et al. | 2005-11-24 |
Sequential delivery of oligomeric compounds
App 20050260755 - Baker, Brenda F. ; et al. | 2005-11-24 |
Antisense modulation of interleukin 12 P35 subunit expression
App 20050261228 - Bennett, C. Frank ; et al. | 2005-11-24 |
Double stranded constructs comprising one or more short strands hybridized to a longer strand
App 20050245474 - Baker, Brenda F. ; et al. | 2005-11-03 |
Antisense modulation of TFAP2C expression
App 20050227938 - Bennett, C. Frank ; et al. | 2005-10-13 |
Hepatocyte free uptake assays
App 20050221275 - Bennett, C. Frank ; et al. | 2005-10-06 |
Antisense modulation of sterol regulatory element-binding protein-1 expression
App 20050215504 - Bennett, C. Frank ; et al. | 2005-09-29 |
Antisense modulation of peroxisome proliferator-activated receptor gamma expression
App 20050186567 - McKay, Robert ; et al. | 2005-08-25 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
App 20050187178 - Allerson, Charles ; et al. | 2005-08-25 |
Hepatocyte free uptake assays
App 20050164209 - Bennett, C. Frank ; et al. | 2005-07-28 |
Antisense modulation of interferon gamma receptor 2
App 20050153924 - Bennett, C. Frank ; et al. | 2005-07-14 |
Compositions and their uses directed to transferases
App 20050153925 - Bennett, C. Frank ; et al. | 2005-07-14 |
Modulation of RANKL expression
App 20050148533 - Baker, Brenda F. ; et al. | 2005-07-07 |
Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation
App 20050118605 - Baker, Brenda F. ; et al. | 2005-06-02 |
Compositions and methods for the treatment of severe acute respiratory syndrome (SARS)
App 20050100885 - Crooke, Stanley T. ; et al. | 2005-05-12 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
App 20050080246 - Allerson, Charles ; et al. | 2005-04-14 |
Chimeric oligomeric compounds comprising alternating regions of northern and southern conformational geometry
App 20050074801 - Monia, Brett P. ; et al. | 2005-04-07 |
Chimeric oligomeric compounds and their use in gene modulation
App 20050053976 - Baker, Brenda F. ; et al. | 2005-03-10 |
Antisense oligonucleotide modulation of tumor necrosis factor-alpha (TNF-alpha) expression
App 20050053965 - Baker, Brenda F. ; et al. | 2005-03-10 |
Isoform-specific targeting of splice variants
App 20050048495 - Baker, Brenda F. ; et al. | 2005-03-03 |
Phosphorous-linked oligomeric compounds and their use in gene modulation
App 20050042647 - Baker, Brenda F. ; et al. | 2005-02-24 |
Modulation of the RNA interference pathway
App 20050037387 - Ward, Donna T. ; et al. | 2005-02-17 |
Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation
App 20050037370 - Baker, Brenda F. ; et al. | 2005-02-17 |
Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation
App 20050033524 - Cowsert, Lex M. ; et al. | 2005-02-10 |
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
App 20050026160 - Allerson, Charles ; et al. | 2005-02-03 |
Antisense modulation of cd40 ligand expression
App 20040259824 - Bennett, C Frank ; et al. | 2004-12-23 |
Antisense modulation of interleukin 12 p35 subunit expression
App 20040248828 - Baker, Brenda F. ; et al. | 2004-12-09 |
Antisense modulation of interleukin 12 p40 subunit expression
App 20040241843 - Baker, Brenda F. ; et al. | 2004-12-02 |
Antisense modulation of sap-1 expression
App 20040209358 - Baker, Brenda F ; et al. | 2004-10-21 |
Modified oligonucleotides for use in RNA interference
App 20040203024 - Baker, Brenda F. ; et al. | 2004-10-14 |
System of components for preparing oligonucleotides
App 20040197814 - Cowsert, Lex M. ; et al. | 2004-10-07 |
Non-phosphorous-linked oligomeric compounds and their use in gene modulation
App 20040171032 - Baker, Brenda F. ; et al. | 2004-09-02 |
Oligomeric compounds having modified bases for binding to cytosine and uracil or thymine and their use in gene modulation
App 20040171030 - Baker, Brenda F. ; et al. | 2004-09-02 |
2'-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
App 20040171029 - Prakash, Thazha P. ; et al. | 2004-09-02 |
Sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
App 20040171031 - Baker, Brenda F. ; et al. | 2004-09-02 |
Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation
App 20040171570 - Allerson, Charles ; et al. | 2004-09-02 |
Phosphorous-linked oligomeric compounds and their use in gene modulation
App 20040171028 - Baker, Brenda F. ; et al. | 2004-09-02 |
2'-substituted oligomeric compounds and compositions for use in gene modulations
App 20040171033 - Baker, Brenda F. ; et al. | 2004-09-02 |
Modified oligonucleotides for use in RNA interference
App 20040161777 - Baker, Brenda F. ; et al. | 2004-08-19 |
Sugar and backbone-surrogate-containing oligomeric compounds and compositions for use in gene modulation
App 20040161844 - Baker, Brenda F. ; et al. | 2004-08-19 |
Antisense Oligonucleotide modulation of tumor necrosis factor-alpha (TNF-alpha) expression
App 20040152652 - Baker, Brenda F. ; et al. | 2004-08-05 |
Chimeric oligomeric compounds and their use in gene modulation
App 20040147023 - Baker, Brenda F. ; et al. | 2004-07-29 |
2'-methoxy substituted oligomeric compounds and compositions for use in gene modulations
App 20040147022 - Baker, Brenda F. ; et al. | 2004-07-29 |
Antisense oligonucleotide modulation of tumor necrosis factor-alpha (TNF-alpha) expression
App 20040142346 - Baker, Brenda F. ; et al. | 2004-07-22 |
Delivery of oligonucleotide compounds into osteoclasts and modulation of osteoclast differentiation
App 20040137623 - Baker, Brenda F. ; et al. | 2004-07-15 |
Efficient reduction of target RNA's by single-and double-stranded oligomeric compounds
App 20040137471 - Vickers, Timothy ; et al. | 2004-07-15 |
Antisense modulation of activating transcription factor 3 expression
App 20040121977 - Baker, Brenda F. ; et al. | 2004-06-24 |
Modulation of interleukin 18 expression
App 20040115636 - Baker, Brenda F. ; et al. | 2004-06-17 |
Modulation of matrix metalloproteinase 11 expression
App 20040110152 - Baker, Brenda F. ; et al. | 2004-06-10 |
Antisense modulation of interleukin 8 expression
App 20040043948 - Baker, Brenda F. ; et al. | 2004-03-04 |
Antisense modulation of urokinase plasminogen activator expression
App 20040043957 - Baker, Brenda F. ; et al. | 2004-03-04 |
Antisense modulation of NF-kappa-B p50 subunit expression
App 20040005569 - Baker, Brenda F. ; et al. | 2004-01-08 |
Nuclease-based method for detecting and quantitating oligonucleotides
App 20040005618 - Yu, Zhengrong ; et al. | 2004-01-08 |
Modulation of PTEN expression via oligomeric compounds
App 20040002153 - Monia, Brett P. ; et al. | 2004-01-01 |
Antisense modulation of IL-1 receptor-associated kinase-1 expression
App 20030228690 - Baker, Brenda F. ; et al. | 2003-12-11 |
Identification of genetic targets for modulation by oligonucleotides and generation of oligonucleotides for gene modulation
App 20030228597 - Cowsert, Lex M. ; et al. | 2003-12-11 |
Antisense modulation of sterol regulatory element-binding protein-1 expression
App 20030224515 - Freier, Susan M. ; et al. | 2003-12-04 |
Antisense modulation of transcription factor DP-1 expression
App 20030225012 - Baker, Brenda F. ; et al. | 2003-12-04 |
Antisense modulation of activating transcription factor 3 expression
App 20030125277 - Baker, Brenda F. ; et al. | 2003-07-03 |
Antisense modulation of vitamin D nuclear receptor expression
App 20030125271 - Baker, Brenda F. ; et al. | 2003-07-03 |
System of components for preparing oligonucleotides
App 20030113739 - Cowsert, Lex M. ; et al. | 2003-06-19 |
Antisense modulation of matrix metalloproteinase 1 expression
App 20030105044 - Baker, Brenda F. ; et al. | 2003-06-05 |
Antisense modulation of CD40 ligand expression
App 20030083278 - Bennett, C. Frank ; et al. | 2003-05-01 |
Antisense modulation of expression of tumor necrosis factor receptor-associated factors (TRAFs)
App 20030055015 - Baker, Brenda F. ; et al. | 2003-03-20 |
Antisense oligonucleotide modulation of tumor necrosis factor-alpha (TNF-alpha) expression
App 20030022848 - Baker, Brenda F. ; et al. | 2003-01-30 |
Antisense modulation of expression of tumor necrosis factor receptor-associated factors (TRAFs)
Grant 6,399,297 - Baker , et al. June 4, 2 | 2002-06-04 |
Alteration of cellular behavior by antisense modulation of mRNA processing
App 20020049173 - Bennett, C. Frank ; et al. | 2002-04-25 |
Antisense modulation of inhibitor of DNA binding-1 expression
Grant 6,372,433 - Baker , et al. April 16, 2 | 2002-04-16 |
Identification Of Genetic Targets For Modulation By Oligonucleotides And Generation Of Oligonucleotides For Gene Modulation
App 20020028923 - COWSERT, LEX M. ; et al. | 2002-03-07 |
Antisense oligonucleotide modulation of tumor necrosis factor-(.alpha.) (TNF-.alpha.) expression
Grant 6,228,642 - Baker , et al. May 8, 2 | 2001-05-08 |
Alteration of cellular behavior by antisense modulation of mRNA processing
Grant 6,210,892 - Bennett , et al. April 3, 2 | 2001-04-03 |
Antisense modulation of peroxisome proliferator-activated receptor gamma expression
Grant 6,159,734 - McKay , et al. December 12, 2 | 2000-12-12 |
Antisense oligonucleotide modulation of tumor necrosis factor-.alpha. (TNF-.alpha.) expression
Grant 6,080,580 - Baker , et al. June 27, 2 | 2000-06-27 |
Antisense modulation of FADD expression
Grant 6,015,712 - Monia , et al. January 18, 2 | 2000-01-18 |
Antisense inhibition of Elk-1 expression
Grant 5,948,680 - Baker , et al. September 7, 1 | 1999-09-07 |
Compositions and methods for modulating RNA activity through modification of the 5' cap structure of RNA
Grant 5,643,780 - Baker July 1, 1 | 1997-07-01 |
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