Patent | Date |
---|
Human Artificial Chromosome Containing Human Antibody Lambda Light Chain Gene And Non-human Animal Containing The Human Artificial Chromosome Capable Of Genetic Transmission App 20210298277 - KUROIWA; Yoshimi ;   et al. | 2021-09-30 |
Human Artificial Chromosome Containing Human Antibody Lambda Light Chain Gene And Non-human Animal Containing The Human Artifici App 20200236915 - KUROIWA; Yoshimi ;   et al. | 2020-07-30 |
Pharmaceutical composition for treating bone diseases which comprises protein comprising Frizzled 1, Frizzled 2 or Frizzled 7 extracellular cysteine-rich domain Grant 10,646,544 - Kakitani , et al. | 2020-05-12 |
Human artificial chromosome containing human antibody lambda light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission Grant 10,448,622 - Kuroiwa , et al. Oc | 2019-10-22 |
Transgenic transchromosomal rodents for making human antibodies Grant 10,076,103 - Tomizuka , et al. September 18, 2 | 2018-09-18 |
Pharmaceutical Composition For Treating Bone Diseases Which Comprises Protein Comprising Frizzled1, Frizzled2 Or Frizzled7 Extracellular Cysteine-rich Domain App 20170266255 - KAKITANI; Makoto ;   et al. | 2017-09-21 |
Pharmaceutical composition for treating bone diseases which comprises protein comprising Frizzled1, Frizzled2 or Frizzled7 extracellular cysteine-rich domain Grant 9,700,594 - Kakitani , et al. July 11, 2 | 2017-07-11 |
Anti-death Receptor 3 (dr3) Antagonistic Antibodies With Reduced Agonistic Activity App 20170190781 - MILLS; David ;   et al. | 2017-07-06 |
Human Artificial Chromosome Containing Human Antibody Lambda Light Chain Gene And Non-human Animal Containing The Human Artificial Chromosome Capable Of Genetic Transmission App 20170099814 - KUROIWA; YOSHIMI ;   et al. | 2017-04-13 |
Human artificial chromosome containing human antibody .lamda. light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission Grant 9,499,838 - Kuroiwa , et al. November 22, 2 | 2016-11-22 |
Transgenic Transchromosomal Rodents For Making Human Antibodies App 20160324131 - Tomizuka; Kazuma ;   et al. | 2016-11-10 |
Transgenic transchromosomal rodents for making human antibodies Grant 9,426,970 - Tomizuka , et al. August 30, 2 | 2016-08-30 |
Mammalian artificial chromosome vector comprising human cytochrome P450 gene (cluster) and non-human mammalian animal retaining the same Grant 8,951,789 - Oshimura , et al. February 10, 2 | 2015-02-10 |
Transgenic Transchromosomal Rodents For Making Human Antibodies App 20140380515 - TOMIZUKA; KAZUMA ;   et al. | 2014-12-25 |
Transgenic trasnchromosomal rodents for making human antibodies Grant 8,835,712 - Tomizuka , et al. September 16, 2 | 2014-09-16 |
Human artificial chromosome (HAC) vector and human cell medicine comprising same Grant 8,809,045 - Kakeda , et al. August 19, 2 | 2014-08-19 |
Human artificial chromosome (HAC) vector Grant 8,703,482 - Oshimura , et al. April 22, 2 | 2014-04-22 |
Pharmaceutical Composition For Treating Bone Diseases Which Comprises Protein Comprising Frizzled1, Frizzled2 Or Frizzled7 Extracellular Cysteine-rich Domain App 20130230520 - KAKITANI; Makoto ;   et al. | 2013-09-05 |
Human Artificial Chromosome (hac) Vector App 20120093785 - Oshimura; Mitsuo ;   et al. | 2012-04-19 |
Method for modifying chromosomes Grant 8,124,406 - Tomizuka , et al. February 28, 2 | 2012-02-28 |
Isolated human chromosome 14 fragment encoding immunoglobulin genes Grant 8,110,671 - Tomizuka , et al. February 7, 2 | 2012-02-07 |
PHARMACEUTICAL COMPOSITION FOR TREATING BONE DISEASES WHICH COMPRISES PROTEIN COMPRISING Frizzled1, Frizzled2 OR Frizzled7 EXTRACELLULAR CYSTEINE-RICH DOMAIN App 20110237514 - Kakitani; Makoto ;   et al. | 2011-09-29 |
Transgenic Animals And Uses Thereof App 20110231943 - ROBL; JAMES M. ;   et al. | 2011-09-22 |
Method For Modifying Chromosomes App 20110151518 - Tomizuka; Kazuma ;   et al. | 2011-06-23 |
Method of stimulating epithelial cell proliferation by administration of gastrointestinal proliferative factor Grant 7,951,381 - Funk , et al. May 31, 2 | 2011-05-31 |
Method of producing xenogenous antibodies using a bovine Grant 7,928,285 - Robl , et al. April 19, 2 | 2011-04-19 |
Expression of Xenogenous (Human) Immunoglobulins in cloned, transgenic ungulates App 20110067122 - Robl; James M. ;   et al. | 2011-03-17 |
Mammalian Artificial Chromosome Vector Comprising Human Cytochrome P450 Gene (cluster) And Non-human Mammalian Animal Retaining The Same App 20110023138 - Oshimura; Mitsuo ;   et al. | 2011-01-27 |
Method for modifying chromosomes Grant 7,868,223 - Tomizuka , et al. January 11, 2 | 2011-01-11 |
Transgenic Trasnchromosomal Rodents for Making Human Antibodies App 20110003319 - TOMIZUKA; KAZUMA ;   et al. | 2011-01-06 |
Transgenic transchromosomal rodents for making human antibodies Grant 7,816,578 - Tomizuka , et al. October 19, 2 | 2010-10-19 |
Transgenic bovine having reduced prion protein activity and uses thereof Grant 7,807,863 - Robl , et al. October 5, 2 | 2010-10-05 |
Transgenic ungulates capable of human antibody production Grant 7,803,981 - Robl , et al. September 28, 2 | 2010-09-28 |
Gastrointestinal proliferative foctor and uses thereof App 20100137210 - Funk; Walter ;   et al. | 2010-06-03 |
Human Artificial Chromosome (hac) Vector And Human Cell Medicine Comprising Same App 20100011454 - Kakeda; Minoru ;   et al. | 2010-01-14 |
Chimeric Non-human Animal App 20100011452 - TOMIZUKA; Kazuma ;   et al. | 2010-01-14 |
Isolation of a rearranged human immunoglobulin gene from a chimeric mouse and recombinant production of the encoded immunoglobulin App 20090253902 - Tomizuka; Kazuma ;   et al. | 2009-10-08 |
Transgenic animals and uses thereof App 20090222935 - Robl; James M. ;   et al. | 2009-09-03 |
Transgenic transchromosomal rodents for making human antibodies Grant 7,576,258 - Tomizuka , et al. August 18, 2 | 2009-08-18 |
Transgenic ungulates having reduced prion protein activity and uses thereof App 20090165154 - Robl; James M. ;   et al. | 2009-06-25 |
Chimeric Non-Human Animal and Use Thereof App 20090151011 - Kakitani; Makoto ;   et al. | 2009-06-11 |
Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates Grant 7,491,867 - Robl , et al. February 17, 2 | 2009-02-17 |
Anti-tumor Agents Comprising R-spondins App 20090036369 - Kakitani; Makoto ;   et al. | 2009-02-05 |
Artificial human chromosome containing human antibody a light chain gene Grant 7,476,536 - Kuroiwa , et al. January 13, 2 | 2009-01-13 |
Method For Modifying Chromosomes App 20090007282 - TOMIZUKA; Kazuma ;   et al. | 2009-01-01 |
Human Artificial Chromosome Containing Human Antibody Lambda Light Chain Gene And Non-Human Animal Containing The Human Artificial Chromosome Capable Of Genetic Transmission App 20080317743 - Kuroiwa; Yoshimi ;   et al. | 2008-12-25 |
Gastrointestinal proliferative factor and uses thereof App 20080300183 - Boyle; Bryan J. ;   et al. | 2008-12-04 |
Transgenic bovines having reduced prion protein production Grant 7,429,690 - Robl , et al. September 30, 2 | 2008-09-30 |
Transgenic animals and uses thereof Grant 7,420,099 - Robl , et al. September 2, 2 | 2008-09-02 |
Transgenic bovines capable of human antibody production Grant 7,414,170 - Robl , et al. August 19, 2 | 2008-08-19 |
Human artificial chromosome containing human antibody .lamda. light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission Grant 7,402,729 - Kuroiwa , et al. July 22, 2 | 2008-07-22 |
Method for modifying chromosomes Grant 7,371,568 - Tomizuka , et al. May 13, 2 | 2008-05-13 |
Transgenic ungulates capable of human antibody production App 20080040821 - Robl; James M. ;   et al. | 2008-02-14 |
Human artificial chromosome (hac) vector App 20060185025 - Oshimura; Mitsuo ;   et al. | 2006-08-17 |
Artificial human chromosome containing human antibody a light chain gene App 20060161995 - Kuroiwa; Yoshimi ;   et al. | 2006-07-20 |
Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin Grant 7,074,983 - Robl , et al. July 11, 2 | 2006-07-11 |
Pluripotent cells with improved efficiency of homologous recombination and use of the same App 20060123490 - Kakitani; Makoto ;   et al. | 2006-06-08 |
Expression of xenogenous (human) imunoglobulins in cloned, transgenic ungulates App 20060117394 - Robl; James M. ;   et al. | 2006-06-01 |
Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates App 20060117395 - Robl; James M. ;   et al. | 2006-06-01 |
Transgenic transchromosomal rodents for making human antibodies Grant 7,041,870 - Tomizuka , et al. May 9, 2 | 2006-05-09 |
Transgenic animals and uses thereof App 20060041945 - Robl; James M. ;   et al. | 2006-02-23 |
Transgenic transchromosomal rodents for making human antibodies App 20060037093 - Tomizuka; Kazuma ;   et al. | 2006-02-16 |
Transgenic transchromosomal rodents for making human antibodies App 20060026698 - Tomizuka; Kazuma ;   et al. | 2006-02-02 |
Human artificial chromosome containing human antibody lambda light chain gene and non-human animal containing the human artificial chromosome capable of genetic transmission App 20060015958 - Kuroiwa; Yoshimi ;   et al. | 2006-01-19 |
Gastrointestinal proliferative factor and uses thereof App 20050256044 - Boyle, Bryan J. ;   et al. | 2005-11-17 |
Gastrointestinal proliferative factor and uses thereof App 20050256036 - Boyle, Bryan J. ;   et al. | 2005-11-17 |
Chimeric nonhuman animal App 20050177884 - Tomizuka, Kazuma ;   et al. | 2005-08-11 |
Transgenic ungulates having reduced prion protein activity and uses thereof App 20050097627 - Robl, James M. ;   et al. | 2005-05-05 |
Isolation of a rearranged human immunoglobulin gene from a chimeric mouse and recombinant production of the encoded immunoglobulin App 20040073957 - Tomizuka, Kazuma ;   et al. | 2004-04-15 |
Transgenic ungulates capable of human antibody production App 20040068760 - Robl, James M. ;   et al. | 2004-04-08 |
Chimeric mice that are produced by microcell mediated chromosome transfer and that retain a human antibody gene Grant 6,632,976 - Tomizuka , et al. October 14, 2 | 2003-10-14 |
Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates App 20030037347 - Robl, James M. ;   et al. | 2003-02-20 |
Transgenic transchromosomal rodents for making human antibodies App 20020199213 - Tomizuka, Kazuma ;   et al. | 2002-12-26 |