Patent | Date |
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Novel Tetragalnac And Peptide Containing Conjugates And Methods For Delivery Of Oligonucleotides App 20220289785 - TELLERS; David ;   et al. | 2022-09-15 |
Rna Interference Mediated Inhibition Of Gene Expression Using Chemically Modified Short Interfering Nucleic Acid (sina) App 20220275366 - McSwiggen; James ;   et al. | 2022-09-01 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 11,413,348 - Stanton , et al. August 16, 2 | 2022-08-16 |
Rna Interference Mediated Inhibition Of Gene Expression Using Short Interfering Nucleic Acids (sina) App 20220195433 - Cancilla; Mark ;   et al. | 2022-06-23 |
RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (SINA) Grant 11,332,745 - Ason , et al. May 17, 2 | 2022-05-17 |
Rna Interference Mediated Inhibition Of Gene Expression Using Chemically Modified Short Interfering Nucleic Acid (sina) App 20220056441 - Beigelman; Leonid ;   et al. | 2022-02-24 |
RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA) Grant 11,193,126 - Cancilla , et al. December 7, 2 | 2021-12-07 |
Tetragalnac and peptide containing conjugates and methods for delivery of oligonucleotides Grant 11,117,917 - Tellers , et al. September 14, 2 | 2021-09-14 |
Systemic Delivery Of Myostatin Short Interfering Nucleic Acids (sina) Conjugated To A Lipophilic Moiety App 20210008226 - Tadin-Strapps; Marija ;   et al. | 2021-01-14 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 10,889,815 - Beigelman , et al. January 12, 2 | 2021-01-12 |
Short Interfering Nucleic Acid (sina) Compositions App 20200392499 - Carr; Brian Allen ;   et al. | 2020-12-17 |
Rna Interference Mediated Inhibition Of Prolyl Hydroxylase Domain 2 (phd2) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20200332299 - Ason; Brandon ;   et al. | 2020-10-22 |
RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (SINA) Grant 10,793,860 - Bartz , et al. October 6, 2 | 2020-10-06 |
Short interfering nucleic acid (siNA) molecules containing a 2' internucleoside linkage (3dT) Grant 10,738,308 - Chang , et al. A | 2020-08-11 |
Systemic delivery of myostatin short interfering nucleic acids (siNA) conjugated to a lipophilic moiety Grant 10,729,787 - Tadin-strapps , et al. | 2020-08-04 |
Novel Low Molecular Weight Cationic Lipids For Oligonucleotide Delivery App 20200222540 - Stanton; Matthew G. ;   et al. | 2020-07-16 |
Rna Interference Mediated Inhibition Of Hepatitis B Virus (hbv) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20200199596 - Bartz; Steven ;   et al. | 2020-06-25 |
Short interfering nucleic acid (siNA) compositions Grant 10,689,648 - Carr , et al. | 2020-06-23 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 10,662,428 - Beigelman , et al. | 2020-05-26 |
Single-stranded RNAi agents containing an internal, non-nucleic acid spacer Grant 10,584,335 - Lim , et al. | 2020-03-10 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 10,576,155 - Stanton , et al. | 2020-03-03 |
RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA) Grant 10,577,606 - Ason , et al. | 2020-03-03 |
Post-synthetic orthogonal amidation plus metal catalyzed azide-alkyne cycloaddition click chemistry on siRNA Grant 10,550,385 - Zewge , et al. Fe | 2020-02-04 |
Segmented micro RNA mimetics Grant 10,526,602 - Chorn , et al. J | 2020-01-07 |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference Grant 10,508,277 - Jadhav Dec | 2019-12-17 |
Rna Interference Mediated Inhibition Of Catenin (cadherin-associated Protein), Beta 1 (ctnnb1) Gene Expression Using Short Inter App 20190330639 - Brown; Duncan ;   et al. | 2019-10-31 |
RNA interference mediated inhibition of hepatitis B Virus (HBV) gene expression using short interfering nucleic acid (siNA) Grant 10,407,682 - Bartz , et al. Sept | 2019-09-10 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20190233821 - Beigelman; Leonid ;   et al. | 2019-08-01 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 10,351,852 - McSwiggen , et al. July 16, 2 | 2019-07-16 |
Low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery Grant 10,337,014 - Stanton , et al. | 2019-07-02 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20190194658 - Beigelman; Leonid ;   et al. | 2019-06-27 |
Diester and triester based low molecular weight, biodegradeable cationic lipids for oligonucleotide delivery Grant 10,307,378 - Colletti , et al. | 2019-06-04 |
Novel Tetragalnac And Peptide Containing Conjugates And Methods For Delivery Of Oligonucleotides App 20190153016 - TELLERS; David ;   et al. | 2019-05-23 |
RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA) Grant 10,246,714 - Brown , et al. | 2019-04-02 |
Tetragalnac and peptide containing conjugates and methods for delivery of oligonucleotides Grant 10,221,205 - Tellers , et al. | 2019-03-05 |
SYSTEMIC DELIVERY OF MYOSTATIN SHORT INTERFERING NUCLEIC ACIDS (siNA) CONJUGATED TO A LIPOPHILIC MOIETY App 20190060488 - Tadin-strapps; Marija ;   et al. | 2019-02-28 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20190062746 - Beigelman; Leonid ;   et al. | 2019-02-28 |
Tetragalnac containing conjugates and methods for delivery of oligonucleotides Grant 10,214,742 - Tellers , et al. Feb | 2019-02-26 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20190010497 - Beigelman; Leonid ;   et al. | 2019-01-10 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA) App 20180362977 - Cancilla; Mark ;   et al. | 2018-12-20 |
Chemically Modified Multifunctional Short Interfering Nucleic Acid Molecules That Mediate Rna Interference App 20180346913 - Jadhav; Vasant R. | 2018-12-06 |
SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES CONTAINING A 2' INTERNUCLEOSIDE LINKAGE (3dT) App 20180265869 - Chang; Wonsuk ;   et al. | 2018-09-20 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20180245083 - Beigelman; Leonid ;   et al. | 2018-08-30 |
Novel Low Molecular Weight Cationic Lipids For Oligonucleotide Delivery App 20180208545 - COLLETTI; Steven L. ;   et al. | 2018-07-26 |
Novel Diester And Triester Based Low Molecular Weight, Biodegradeable Cationic Lipids For Oligonucleotide Delivery App 20180193279 - COLLETTI; Steven L. ;   et al. | 2018-07-12 |
Rna Interference Mediated Inhibition Of Hepatitis B Virus (hbv) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20180195071 - Bartz; Steven ;   et al. | 2018-07-12 |
Systemic delivery of myostatin short interfering nucleic acids (siNA) conjugated to a lipophilic moiety Grant 10,004,814 - Tadin-Strapps , et al. June 26, 2 | 2018-06-26 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 10,000,754 - Beigelman , et al. June 19, 2 | 2018-06-19 |
Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference Grant 9,994,853 - Jadhav June 12, 2 | 2018-06-12 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,981,907 - Colletti , et al. May 29, 2 | 2018-05-29 |
RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA) Grant 9,970,005 - Cancilla , et al. May 15, 2 | 2018-05-15 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,957,517 - Beigelman , et al. May 1, 2 | 2018-05-01 |
Segmented Micro Rna Mimetics App 20180112216 - Chorn; Guillaume ;   et al. | 2018-04-26 |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS App 20180105812 - Carr; Brian Allen ;   et al. | 2018-04-19 |
Rna Interference Mediated Inhibition Of Prolyl Hydroxylase Domain 2 (phd2) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20180100154 - Ason; Brandon ;   et al. | 2018-04-12 |
Novel Tetragalnac And Peptide Containing Conjugates And Methods For Delivery Of Oligonucleotides App 20180079769 - TELLERS; David ;   et al. | 2018-03-22 |
Single-stranded Rnai Agents Containing An Internal, Non-nucleic Acid Spacer App 20180080024 - Lim; Lee ;   et al. | 2018-03-22 |
Short interfering nucleic acid (siNA) molecules containing a 2' internucleoside linkage Grant 9,896,688 - Chang , et al. February 20, 2 | 2018-02-20 |
Novel Low Molecular Weight Cyclic Amine Containing Cationic Lipids For Oligonucleotide Delivery App 20180037893 - STANTON; Matthew G. ;   et al. | 2018-02-08 |
Rna Interference Mediated Inhibition Of Catenin (cadherin-associated Protein), Beta 1 (ctnnb1) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20180030454 - Brown; Duncan ;   et al. | 2018-02-01 |
RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA) Grant 9,879,262 - Bartz , et al. January 30, 2 | 2018-01-30 |
Diester and triester based low molecular weight, biodegradeable cationic lipids for oligonucleotide delivery Grant 9,861,589 - Colletti , et al. January 9, 2 | 2018-01-09 |
Novel Low Molecular Weight Cationic Lipids For Oligonucleotide Delivery App 20180000939 - Stanton; Matthew G. ;   et al. | 2018-01-04 |
RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA) Grant 9,850,491 - Brown , et al. December 26, 2 | 2017-12-26 |
Single-stranded RNAi agents containing an internal, non-nucleic acid spacer Grant 9,845,466 - Lim , et al. December 19, 2 | 2017-12-19 |
Tetragalnac and peptide containing conjugates and methods for delivery of oligonucleotides Grant 9,840,531 - Tellers , et al. December 12, 2 | 2017-12-12 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20170342416 - McSwiggen; James ;   et al. | 2017-11-30 |
Novel Tetragalnac And Peptide Containing Conjugates And Methods For Delivery Of Oligonucleotides App 20170306324 - TELLERS; David ;   et al. | 2017-10-26 |
Low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery Grant 9,796,977 - Stanton , et al. October 24, 2 | 2017-10-24 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20170298355 - Beigelman; Leonid ;   et al. | 2017-10-19 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20170283816 - Beigelman; Leonid ;   et al. | 2017-10-05 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,771,588 - McSwiggen , et al. September 26, 2 | 2017-09-26 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,738,899 - Beigelman , et al. August 22, 2 | 2017-08-22 |
Novel Tetragalnac Containing Conjugates And Methods For Delivery Of Oligonucleotides App 20170233731 - TELLERS; David ;   et al. | 2017-08-17 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,732,344 - Beigelman , et al. August 15, 2 | 2017-08-15 |
Segmented micro RNA mimetics Grant 9,732,342 - Chorn , et al. August 15, 2 | 2017-08-15 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,725,720 - Bawiec, III , et al. August 8, 2 | 2017-08-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20170211083 - Beigelman; Leonid ;   et al. | 2017-07-27 |
Cationic lipids for oligonucleotide delivery Grant 9,670,487 - Colletti , et al. June 6, 2 | 2017-06-06 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,669,097 - Stanton , et al. June 6, 2 | 2017-06-06 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,657,294 - Beigelman , et al. May 23, 2 | 2017-05-23 |
Tetragalnac and peptide containing conjugates and methods for delivery of oligonucleotides Grant 9,655,976 - Tellers , et al. May 23, 2 | 2017-05-23 |
Novel Single Chemical Entities And Methods For Delivery Of Oligonucleotides App 20170137815 - COLLETTI; Steven L. ;   et al. | 2017-05-18 |
Novel Diester And Triester Based Low Molecular Weight, Biodegradeable Cationic Lipids For Oligonucleotide Delivery App 20170135962 - COLLETTI; Steven L. ;   et al. | 2017-05-18 |
Cationic lipids with various head groups for oligonucleotide delivery Grant 9,642,804 - Cameron , et al. May 9, 2 | 2017-05-09 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,643,916 - Budzik , et al. May 9, 2 | 2017-05-09 |
Diether based biodegradable cationic lipids for siRNA delivery Grant 9,604,908 - Stanton , et al. March 28, 2 | 2017-03-28 |
Novel Low Molecular Weight Cationic Lipids For Oligonucleotide Delivery App 20170050917 - BUDZIK; Brian W. ;   et al. | 2017-02-23 |
Rna Interference Mediated Inhibition Of Catenin (cadherin-associated Protein), Beta 1 (ctnnb1) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20170029824 - Brown; Duncan ;   et al. | 2017-02-02 |
Novel Low Molecular Weight Cationic Lipids For Oligonucleotide Delivery App 20170022146 - COLLETTI; Steven L. ;   et al. | 2017-01-26 |
Low Molecular Weight Cationic Lipids For Oligonucleotide Delivery App 20170015998 - BAWIEC, III; John A. ;   et al. | 2017-01-19 |
Tetragalnac containing conjugates and methods for delivery of oligonucleotides Grant 9,540,639 - Tellers , et al. January 10, 2 | 2017-01-10 |
DIETHER BASED BIODEGRADABLE CATIONIC LIPIDS FOR siRNA DELIVERY App 20170001947 - STANTON; Matthew G. ;   et al. | 2017-01-05 |
Rna Interference Mediated Inhibition Of Hepatitis B Virus (hbv) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20160369279 - Bartz; Steven ;   et al. | 2016-12-22 |
Method for rapidly evaluating performance of short interfering RNA with novel chemical modifications Grant 9,512,426 - Butora , et al. December 6, 2 | 2016-12-06 |
Post-synthetic Chemical Modification Of Rna At The 2'-position Of The Ribose Ring Via "click" Chemistry App 20160348109 - ZEWGE; Daniel ;   et al. | 2016-12-01 |
Rna Interference Mediated Inhibition Of Prolyl Hydroxylase Domain 2 (phd2) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20160298123 - Ason; Brandon ;   et al. | 2016-10-13 |
RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA) Grant 9,464,290 - Bartz , et al. October 11, 2 | 2016-10-11 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,458,087 - Bawiec, III , et al. October 4, 2 | 2016-10-04 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,458,090 - Colletti , et al. October 4, 2 | 2016-10-04 |
Chemically Modified Short Interfering Nucleic Acid Molecules That Mediate Rna Interference App 20160272975 - JADHAV; Vasant R. | 2016-09-22 |
Diether based biodegradable cationic lipids for siRNA delivery Grant 9,446,132 - Stanton , et al. September 20, 2 | 2016-09-20 |
RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (SINA) Grant 9,447,420 - Brown , et al. September 20, 2 | 2016-09-20 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA) App 20160264964 - Cancilla; Mark ;   et al. | 2016-09-15 |
Post-synthetic chemical modification of RNA at the 2'-position of the ribose ring via "click" chemistry Grant 9,441,228 - Zewge , et al. September 13, 2 | 2016-09-13 |
Rna Interference Mediated Inhibition Of Isocitrate Dehydrogenase (idh1) Gene Expression App 20160257962 - Ma; Yong ;   et al. | 2016-09-08 |
SYSTEMIC DELIVERY OF MYOSTATIN SHORT INTERFERING NUCLEIC ACIDS (siNA) CONJUGATED TO A LIPOPHILIC MOIETY App 20160256570 - Tadin-Strapps; Marija ;   et al. | 2016-09-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20160244760 - Beigelman; Leonid ;   et al. | 2016-08-25 |
Single-stranded Rnai Agents Containing An Internal, Non-nucleic Acid Spacer App 20160222381 - Lim; Lee ;   et al. | 2016-08-04 |
Membrane lytic poly(amido amine) polymers for the delivery of oligonucleotides Grant 9,402,914 - Busuek , et al. August 2, 2 | 2016-08-02 |
Diester and triester based low molecular weight, biodegradeable cationic lipids for oligonucleotide delivery Grant 9,402,816 - Colletti , et al. August 2, 2 | 2016-08-02 |
Chemically Modified Short Interfering Nucleic Acid Molecules That Mediate Rna Interference App 20160152973 - Jadhav; Vasant R. | 2016-06-02 |
Novel Catatonic Lipids With Various Head Groups For Oligonucleotide Delivery App 20160113874 - CAMERON; Mark ;   et al. | 2016-04-28 |
RNA interference mediated inhibition of isocitrate dehydrogenase (IDH1) gene expression Grant 9,322,020 - Ma , et al. April 26, 2 | 2016-04-26 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,315,437 - Budzik , et al. April 19, 2 | 2016-04-19 |
Novel Single Chemical Entities And Methods For Delivery Of Oligonucleotides App 20160074525 - COLLETTI; Steven L. ;   et al. | 2016-03-17 |
Rna Interference Mediated Inhibition Of Hepatitis B Virus (hbv) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20160076034 - Bartz; Steven ;   et al. | 2016-03-17 |
SHORT INTERFERING NUCLEIC ACID (siNA) MOLECULES CONTAINING A 2' INTERNUCLEOSIDE LINKAGE App 20160068837 - Chang; Wonsuk ;   et al. | 2016-03-10 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20160053269 - Beigelman; Leonid ;   et al. | 2016-02-25 |
RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA) Grant 9,260,471 - Cancilla , et al. February 16, 2 | 2016-02-16 |
Single-stranded RNAi agents containing an internal, non-nucleic acid spacer Grant 9,243,246 - Lim , et al. January 26, 2 | 2016-01-26 |
RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA) Grant 9,233,997 - Ason , et al. January 12, 2 | 2016-01-12 |
Segmented Micro Rna Mimetics App 20150376613 - Chorn; Guillaume ;   et al. | 2015-12-31 |
Novel Ph -switchable Peptides For Membrane Insertion And Pore Formation App 20150374844 - DEGRADO; William ;   et al. | 2015-12-31 |
Novel Low Molecular Weight Cyclic Amine Containing Cationic Lipids For Oligonucleotide Delivery App 20150361434 - STANTON; Matthew G. ;   et al. | 2015-12-17 |
POST-SYNTHETIC ORTHOGANAL AMIDATION PLUS METAL CATALYZED AZIDE-ALKYNE CYCLOADDITION CLICK CHEMISTRY ON siRNA App 20150322433 - Zewge; Daniel ;   et al. | 2015-11-12 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 9,181,551 - McSwiggen , et al. November 10, 2 | 2015-11-10 |
Cationic lipids with various head groups for oligonucleotide delivery Grant 9,181,295 - Cameron , et al. November 10, 2 | 2015-11-10 |
Novel Low Molecular Weight Cationic Lipids For Oligonucleotide Delivery App 20150315112 - BUDZIK; Brian W. ;   et al. | 2015-11-05 |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS App 20150299696 - Carr; Brian Allen ;   et al. | 2015-10-22 |
Novel Low Molecular Weight Cationic Lipids For Oligonucleotide Delivery App 20150284317 - COLLETTI; Steven L. ;   et al. | 2015-10-08 |
Low Molecular Weight Cationic Lipids For Oligonucleotide Delivery App 20150284316 - BAWIEC, III; John A. ;   et al. | 2015-10-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20150267200 - McSwiggen; James ;   et al. | 2015-09-24 |
Segmented micro RNA mimetics Grant 9,096,850 - Chorn , et al. August 4, 2 | 2015-08-04 |
Post-synthetic Chemical Modification Of Rna At The 2'-position Of The Ribose Ring Via "click" Chemistry App 20150211008 - ZEWGE; Daniel ;   et al. | 2015-07-30 |
Novel Tetragalnac Containing Conjugates And Methods For Delivery Of Oligonucleotides App 20150203843 - Tellers; David ;   et al. | 2015-07-23 |
Low molecular weight cyclic amine containing cationic lipids for oligonucleotide delivery Grant 9,067,882 - Stanton , et al. June 30, 2 | 2015-06-30 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,062,021 - Budzik , et al. June 23, 2 | 2015-06-23 |
Membrane Lytic Poly(amido Amine) Polymers For The Delivery Of Oligonucleotides App 20150165058 - Busuek; Marina ;   et al. | 2015-06-18 |
Amino alcohol cationic lipids for oligonucleotide delivery Grant 9,044,512 - Budzik , et al. June 2, 2 | 2015-06-02 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20150148530 - McSwiggen; James ;   et al. | 2015-05-28 |
Method For Rapidly Evaluating Performance Of Short Interfering Rna With Novel Chemical Modifications App 20150132761 - Butora; Gabor ;   et al. | 2015-05-14 |
Novel Diester And Triester Based Low Molecular Weight, Biodegradeable Cationic Lipids For Oligonucleotide Delivery App 20150133519 - Colletti; Steven L. ;   et al. | 2015-05-14 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,029,590 - Colletti , et al. May 12, 2 | 2015-05-12 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 9,029,604 - Bawiec, III , et al. May 12, 2 | 2015-05-12 |
RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA) Grant 9,029,341 - Bartz , et al. May 12, 2 | 2015-05-12 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20150105445 - McSwiggen; James ;   et al. | 2015-04-16 |
DIETHER BASED BIODEGRADABLE CATIONIC LIPIDS FOR siRNA DELIVERY App 20150057373 - Stanton; Matthew G. ;   et al. | 2015-02-26 |
Membrane lytic poly(amido amine) polymers for the delivery of oligonucleotides Grant 8,901,101 - Busuek , et al. December 2, 2 | 2014-12-02 |
Rna Interference Mediated Inhibition Of Catenin (cadherin-associated Protein), Beta 1 (ctnnb1) Gene Expression Using Short Interfering Nucleic Acid (sina) App 20140343126 - Brown; Duncan ;   et al. | 2014-11-20 |
Method for rapidly evaluating performance of short interfering RNA with novel chemical modifications Grant 8,877,439 - Butora , et al. November 4, 2 | 2014-11-04 |
Novel Amino Alcohol Cationic Lipids For Oligonucleotide Delivery App 20140323548 - BUDZIK; Brian W. ;   et al. | 2014-10-30 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 8,846,894 - McSwiggen , et al. September 30, 2 | 2014-09-30 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20140288148 - Beigelman; Leonid ;   et al. | 2014-09-25 |
RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA) Grant 8,835,623 - Brown , et al. September 16, 2 | 2014-09-16 |
Amino alcohol cationic lipids for oligonucleotide delivery Grant 8,802,863 - Budzik , et al. August 12, 2 | 2014-08-12 |
Low molecular weight cationic lipids for oligonucleotide delivery Grant 8,748,667 - Budzik , et al. June 10, 2 | 2014-06-10 |
Conjugates and compositions for cellular delivery Grant 8,461,313 - Matulic-Adamic , et al. June 11, 2 | 2013-06-11 |
RNA interference mediated inhibition of respiratory syncytial virus (RSV) expression using short interfering nucleic acid (siNA) Grant 8,258,288 - McSwiggen , et al. September 4, 2 | 2012-09-04 |
Conjugates and Compositions for Cellular Delivery App 20120202983 - Matulic-Adamic; Jasenka ;   et al. | 2012-08-09 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 8,232,383 - McSwiggen , et al. July 31, 2 | 2012-07-31 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid Grant 8,202,979 - McSwiggen , et al. June 19, 2 | 2012-06-19 |
Conjugates and compositions for cellular delivery Grant 8,188,247 - Beigelman , et al. May 29, 2 | 2012-05-29 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 7,989,612 - McSwiggen , et al. August 2, 2 | 2011-08-02 |
RNA Interference Mediated Inhibition of Vascular Cell Adhesion Molecule (VCAM) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20110160281 - McSwiggen; James ;   et al. | 2011-06-30 |
Conjugates and compositions for cellular delivery Grant 7,964,578 - Vargeese , et al. June 21, 2 | 2011-06-21 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 7,956,176 - McSwiggen , et al. June 7, 2 | 2011-06-07 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) Grant 7,923,547 - McSwiggen , et al. April 12, 2 | 2011-04-12 |
RNA interference mediated inhibition of Fos gene expression using short interfering nucleic acid (siNA) Grant 7,910,724 - McSwiggen , et al. March 22, 2 | 2011-03-22 |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA) Grant 7,910,725 - McSwiggen , et al. March 22, 2 | 2011-03-22 |
RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA) Grant 7,897,752 - McSwiggen , et al. March 1, 2 | 2011-03-01 |
RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA) Grant 7,897,755 - McSwiggen , et al. March 1, 2 | 2011-03-01 |
RNA interference mediated inhibition of XIAP gene expression using short interfering nucleic acid (siNA) Grant 7,897,753 - McSwiggen , et al. March 1, 2 | 2011-03-01 |
Deprotection and purification of oligonucleotides and their derivatives Grant 7,893,249 - Bowman , et al. February 22, 2 | 2011-02-22 |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules Grant 7,893,302 - Chen , et al. February 22, 2 | 2011-02-22 |
RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA) Grant 7,893,248 - McSwiggen , et al. February 22, 2 | 2011-02-22 |
RNA interference mediated inhibition of gene expression using multifunctional short interfering nucleic acid (multifunctional siNA) Grant 7,858,769 - Jadhav , et al. December 28, 2 | 2010-12-28 |
Conjugates and compositions for cellular delivery Grant 7,858,625 - Matulic-Adamic , et al. December 28, 2 | 2010-12-28 |
RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA) Grant 7,855,284 - McSwiggen , et al. December 21, 2 | 2010-12-21 |
RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA) Grant 7,795,422 - McSwiggen , et al. September 14, 2 | 2010-09-14 |
Method for the chemical synthesis of oligonucleotides Grant 7,777,023 - Vargeese , et al. August 17, 2 | 2010-08-17 |
Deprotection And Purification Of Oligonucleotides And Their Derivatives App 20100197901 - BOWMAN; KEITH ;   et al. | 2010-08-05 |
RNA Interference Mediated Inhibition of Interleukin and Interleukin Receptor Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100184824 - McSwiggen; James ;   et al. | 2010-07-22 |
RNA Interference Mediated Inhibition of Platelet-Derived Endothelial Cell Growth Factor (ECGF1) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100144851 - McSwiggen; James ;   et al. | 2010-06-10 |
RNA Interference Mediated Inhibition of NOGO and NOGO Receptor Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100144842 - McSwiggen; James ;   et al. | 2010-06-10 |
RNA Interference Mediated Inhibition of GRB2 Associated Binding Protein (GAB2) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20100130592 - MCSWIGGEN; JAMES ;   et al. | 2010-05-27 |
RNA INTERFERENCE MEDIATED INHIBITION OF MUSCARINIC COLINERGIC RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100099750 - McSwiggen; James ;   et al. | 2010-04-22 |
RNA INTERFERENCE MEDIATED INHIBITION OF MATRIX METALLOPROTEINASE 13 (MMP13) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100099744 - McSwiggen; James ;   et al. | 2010-04-22 |
RNA INTERFERENCE MEDIATED INHIBITION OF CHECKPOINT KINASE-1 (CHK-1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100099743 - McSwiggen; James ;   et al. | 2010-04-22 |
RNA interference mediated inhibition of vascular cell adhesion molecule (VCAM) gene expression using short interfering nucleic acid (siNA) Grant 7,700,760 - McSwiggen , et al. April 20, 2 | 2010-04-20 |
RNA INTERFERENCE MEDIATED INHIBITION OF MYC AND/OR MYB GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20100093835 - McSwiggen; James ;   et al. | 2010-04-15 |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules Grant 7,691,405 - Chen , et al. April 6, 2 | 2010-04-06 |
RNA interference mediated inhibition of NOGO and NOGO receptor gene expression using short interfering nucleic acid (siNA) Grant 7,691,999 - McSwiggen , et al. April 6, 2 | 2010-04-06 |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA) Grant 7,683,165 - McSwiggen , et al. March 23, 2 | 2010-03-23 |
RNA interference mediated inhibition of interleukin and interleukin receptor gene expression using short interfering nucleic acid (siNA) Grant 7,683,166 - McSwiggen , et al. March 23, 2 | 2010-03-23 |
RNA interference mediated inhibition of platelet-derived endothelial cell growth factor (ECGF1) gene expression using short interfering nucleic acid (siNA) Grant 7,678,897 - McSwiggen , et al. March 16, 2 | 2010-03-16 |
RNA interference mediated inhibition of checkpoint kinase-1 (CHK-1) gene expression using short interfering nucleic acid (siNA) Grant 7,667,029 - McSwiggen , et al. February 23, 2 | 2010-02-23 |
RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA) Grant 7,667,030 - McSwiggen , et al. February 23, 2 | 2010-02-23 |
RNA interference mediated inhibition of GRB2 associated binding protein (GAB2) gene expression using short interfering nucleic acid (siNA) Grant 7,662,952 - McSwiggen , et al. February 16, 2 | 2010-02-16 |
RNA interference mediated treatment of Alzheimer's disease using short interfering nucleic acid (siNA) Grant 7,662,951 - McSwiggen , et al. February 16, 2 | 2010-02-16 |
Novel Compositions for the Delivery of Negatively Charged Molecules App 20100036115 - Beigelman; Leonid ;   et al. | 2010-02-11 |
RNA interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (siNA) Grant 7,659,390 - McSwiggen , et al. February 9, 2 | 2010-02-09 |
RNA interference mediated inhibition of MYC and/or MYB gene expression using short interfering nucleic acid (siNA) Grant 7,659,389 - McSwiggen , et al. February 9, 2 | 2010-02-09 |
Deprotection and purification of oligonucleotides and their derivatives Grant 7,655,790 - Vargeese , et al. February 2, 2 | 2010-02-02 |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules Grant 7,641,915 - Chen , et al. January 5, 2 | 2010-01-05 |
RNA INTERFERENCE MEDIATED INHIBITION OF MAP KINASE GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090306182 - McSwiggen; James ;   et al. | 2009-12-10 |
RNA Interference Mediated Inhibition of Severe Acute Respiratory Syndrome (SARS) Virus Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20090298914 - McSwiggen; James | 2009-12-03 |
RNA Interference Mediated Inhibition Of Interleukin and Interleukin Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20090299045 - Richards; Ivan ;   et al. | 2009-12-03 |
RNA INTERFERENCE MEDIATED INHIBITION OF RESPIRATORY SYNCYTIAL VIRUS (RSV) EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090281164 - McSwiggen; James ;   et al. | 2009-11-12 |
Conjugates And Compositions For Cellular Delivery App 20090264636 - Vargeese; Chandra ;   et al. | 2009-10-22 |
RNA INTERFERENCE MEDIATED INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090264504 - McSwiggen; James ;   et al. | 2009-10-22 |
RNA INTERFERENCE MEDIATED INHIBITION OF PLATELET DERIVED GROWTH FACTOR (PDGF) AND PLATELET DERIVED GROWTH FACTOR RECEPTOR (PDGFR) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090253774 - McSwiggen; James ;   et al. | 2009-10-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF CXCR4 GENE EXPRESSION USING SHORT INTERFERING NUCELEIC ACID (siNA) App 20090253772 - McSwiggen; James ;   et al. | 2009-10-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF TNF AND TNF RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090253773 - McSwiggen; James ;   et al. | 2009-10-08 |
RNA INTERFERENCE MEDIATED INHIBITION OF B-CELL CLL/LYMPHOMA-2 (BCL2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090247613 - McSwiggen; James ;   et al. | 2009-10-01 |
RNA Interference Mediated Inhibition of Adenosine A1 Receptor (ADORA1) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20090247606 - McSwiggen; James ;   et al. | 2009-10-01 |
RNA INTERFERENCE MEDIATED INHIBITION OF PROTEIN TYROSINE PHOSPHATASE-1B (PTP-1B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090239931 - McSwiggen; James ;   et al. | 2009-09-24 |
RNA Interference Mediated Inhibition of Protein Tyrosine Phosphatase-1B (PTP-1B) Gene Expression Using Short Interfering RNA App 20090233983 - McSwiggen; James A. | 2009-09-17 |
2' Deoxy-2'-Alkylnucleotide Containing Nucleic Acid App 20090221807 - Usman; Nassim ;   et al. | 2009-09-03 |
RNA INTERFERENCE MEDIATED INHIBITION OF HYPOXIA INDUCIBLE FACTOR 1 (HIF1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090192104 - McSwiggen; James ;   et al. | 2009-07-30 |
RNA INTERFERENCE MEDIATED INHIBITION OF INTERCELLULAR ADHESION MOLECULE (ICAM) GENE EXPRESSION USING SHORT INTERFERING NUCELIC ACID (siNA) App 20090192105 - McSwiggen; James ;   et al. | 2009-07-30 |
Chemically Modified Short Interfering Nucleic Acid Molecules That Mediate Rna Interference App 20090176725 - Morrissey; David ;   et al. | 2009-07-09 |
Nucleic Acid-Mediated Treatment of Diseases or Conditions Related to Levels of Vascular Endothelial Growth Factor Receptor (VEGF-R) App 20090170197 - Pavco; Pamela ;   et al. | 2009-07-02 |
Compositions for the delivery of negatively charged molecules Grant 7,553,830 - Beigelman , et al. June 30, 2 | 2009-06-30 |
RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS C VIRUS (HCV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090156528 - McSwiggen; James ;   et al. | 2009-06-18 |
RNA INTERFERENCE MEDIATED INHIBITION OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090156533 - McSwiggen; James ;   et al. | 2009-06-18 |
RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090149407 - McSwiggen; James ;   et al. | 2009-06-11 |
RNA INTERFERENCE MEDIATED INHIBITION OF TELOMERASE GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090149408 - McSwiggen; James ;   et al. | 2009-06-11 |
RNA INTERFERENCE MEDIATED INHIBITION OF INTERLEUKIN AND INTERLEUKIN RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090143324 - McSwiggen; James ;   et al. | 2009-06-04 |
RNA INTERFERENCE MEDIATED INHIBITION OF INTERLEUKIN AND INTERLEUKIN RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090143325 - McSwiggen; James ;   et al. | 2009-06-04 |
RNA INTERFERENCE MEDIATED INHIBITION OF ANGIOPOIETIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090137507 - MCSWIGGEN; JAMES ;   et al. | 2009-05-28 |
RNA INTERFERENCE MEDIATED INHIBITION OF PLACENTAL GROWTH FACTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090137511 - McSwiggen; James ;   et al. | 2009-05-28 |
RNA Interference Mediated Inhibition of Cyclin D1 Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20090137512 - McSwiggen; James ;   et al. | 2009-05-28 |
RNA Interference Mediated Inhibition of Cyclic Nucleotide Type 4 Phosphodiesterase (PDE4B) Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20090137506 - Strapps; Walter ;   et al. | 2009-05-28 |
RNA INTERFERENCE MEDIATED INHIBITION OF POLYCOMB GROUP PROTEIN EZH2 GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090137508 - McSwiggen; James ;   et al. | 2009-05-28 |
RNA Interference Mediated Inhibition of Acetyl-CoA-Carboxylase Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20090137513 - MCSWIGGEN; JAMES ;   et al. | 2009-05-28 |
RNA INTERFERENCE MEDIATED INHIBITION OF NF-KAPPA B/ REL-A GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090137510 - McSwiggen; James ;   et al. | 2009-05-28 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20090137500 - McSwiggen; James ;   et al. | 2009-05-28 |
RNA INTERFERENCE MEDIATED INHIBITION OF PROLIFERATION CELL NUCLEAR ANTIGEN (PCNA) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090137509 - McSwiggen; James ;   et al. | 2009-05-28 |
RNA INTERFERENCE MEDIATED INHIBITION OF PLATELET-DERIVED ENDOTHELIAL CELL GROWTH FACTOR (ECGF1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090105178 - McSwiggen; James ;   et al. | 2009-04-23 |
Detection and quantitation of nucleic acid molecules in biological samples Grant 7,521,184 - Radka , et al. April 21, 2 | 2009-04-21 |
RNA INTERFERENCE MEDIATED INHIBITION OF RAS GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090099119 - McSwiggen; James ;   et al. | 2009-04-16 |
RNA INTERFERENCE MEDIATED INHIBITION OF MYOSTATIN GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090099117 - McSwiggen; James ;   et al. | 2009-04-16 |
RNA INTERFERENCE MEDIATED INHIBITION OF MUSCARINIC COLINERGIC RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090099120 - McSwiggen; James ;   et al. | 2009-04-16 |
RNA INTERFERENCE MEDIATED INHIBITION OF FOS GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090099116 - McSwiggen; James ;   et al. | 2009-04-16 |
RNA INTERFERENCE MEDIATED INHIBITION OF MYC AND/OR MYB GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090099115 - McSwiggen; James ;   et al. | 2009-04-16 |
RNA INTERFERENCE MEDIATED INHIBITION OF STEAROYL-CoA DESATURASE (SCD) GENE EXPRESSION USING SHORT INTERFERING NUCELIC ACID (siNA) App 20090099118 - McSwiggen; James ;   et al. | 2009-04-16 |
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) Grant 7,517,864 - Vargeese , et al. April 14, 2 | 2009-04-14 |
RNA INTERFERENCE MEDIATED INHIBITION OF VASCULAR CELL ADHESION MOLECULE (VCAM) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090093436 - McSwiggen; James ;   et al. | 2009-04-09 |
RNA INTERFERENCE MEDIATED INHIBITION OF XIAP GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090093438 - McSwiggen; James ;   et al. | 2009-04-09 |
RNA INTERFERENCE MEDIATED INHIBITION OF NOGO AND NOGO RECEPTOR GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090093431 - McSwiggen; James ;   et al. | 2009-04-09 |
RNA INTERFERENCE MEDIATED INHIBITION OF CHROMOSOME TRANSLOCATION GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090093439 - McSwiggen; James ;   et al. | 2009-04-09 |
RNA INTERFERENCE MEDIATED INHIBITION OF GRB2 ASSOCIATED BINDING PROTEIN (GAB2) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090093435 - McSwiggen; James ;   et al. | 2009-04-09 |
RNA INTERFERENCE MEDIATED INHIBITION OF CHECKPOINT KINASE-1 (CHK-1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20090093437 - McSwiggen; James ;   et al. | 2009-04-09 |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules Grant 7,514,099 - Chen , et al. April 7, 2 | 2009-04-07 |
Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules App 20090048197 - Chen; Tongqian ;   et al. | 2009-02-19 |
Conjugates and compositions for cellular delivery Grant 7,491,805 - Vargeese , et al. February 17, 2 | 2009-02-17 |
RNA Interference Mediated Inhibition of Gene Expression Using Chemically Modified Short Interfering Nucleic Acid (siNA) App 20090023675 - McSwiggen; James ;   et al. | 2009-01-22 |
RNA Interference Mediated Inhibition of MAP Kinase Gene Expression or Expression of Genes Involved in MAP Kinase Pathway Using Short Interfering Nucleic Acid (SiNA) App 20090023676 - McSwiggen; James ;   et al. | 2009-01-22 |
RNA Interference Mediated Inhibition of Gene Expression Using Short Interfering Nucleic Acid (siNA) App 20080249294 - Haeberli; Peter ;   et al. | 2008-10-09 |
RNA interference mediated inhibition of sterol regulatory element binding protein 1 (SREBP1) gene expression using short interfering nucleic acid (siNA) App 20080249040 - McSwiggen; James ;   et al. | 2008-10-09 |
RNA inteference mediated inhibition of hepatitis C virus (HVC) gene expression using short interfering nucleic acid (siNA) App 20080207542 - McSwiggen; James ;   et al. | 2008-08-28 |
RNA interference mediated inhibition of hypoxia inducible factor 1 (HIF1) gene expression using short interfering nucleic acid (siNA) App 20080188430 - Usman; Nassim ;   et al. | 2008-08-07 |
Lipid Nanoparticle Based Compositions And Methods For The Delivery Of Biologically Active Molecules App 20080188675 - Chen; Tongqian ;   et al. | 2008-08-07 |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules Grant 7,404,969 - Chen , et al. July 29, 2 | 2008-07-29 |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) App 20080161256 - Morrisey; David ;   et al. | 2008-07-03 |
Detection and Quantitation of Nucleic Acid Molecules in Biological Samples App 20080050721 - Radka; Susan ;   et al. | 2008-02-28 |
Rna Interference Mediated Inhibition of Gene Expression Using Multifunctional Short Interfering Nucleic Acid (Multifunctional Sina) App 20080039412 - Jadhav; Vasant ;   et al. | 2008-02-14 |
Polycationic compositions for cellular delivery of polynucleotides App 20080033156 - Vargeese; Chandra ;   et al. | 2008-02-07 |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules App 20080020058 - Chen; Tongqian ;   et al. | 2008-01-24 |
Rna Interference Mediated Inhibition of Severe Acute Respiratory Syndrome (Sars) Gene Expression Using Short Interfering Nucleic Acid App 20070270360 - McSwiggen; James ;   et al. | 2007-11-22 |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) App 20070270579 - Jadhav; Vasant ;   et al. | 2007-11-22 |
RNA interference mediated inhibition of histone deacetylase (HDAC) gene expression using short interfering nucleic acid (siNA) App 20070185049 - Jadhav; Vasant ;   et al. | 2007-08-09 |
RNA interference mediated inhibition of winged helix nude (WHN) gene expression using short interfering nucleic acid (siNA) App 20070179104 - McSwiggen; James | 2007-08-02 |
RNA interference mediated inhibition of proprotein convertase subtilisin Kexin 9 (PCSK9) gene expression using short interfering nucleic acid (siNA) App 20070173473 - McSwiggen; James ;   et al. | 2007-07-26 |
Rna interference mediated inhibition of cholesteryl ester transfer protein (cetp) gene expression using short interfering nucleic acid (sina) App 20070173467 - McSwiggen; James ;   et al. | 2007-07-26 |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA) App 20070167393 - McSwiggen; James ;   et al. | 2007-07-19 |
RNA INTERFERENCE MEDIATED TREATMENT OF ALZHEIMER'S DISEASE USING SHORT INTERFERING NUCLEIC ACID (siNA) App 20070161596 - McSwiggen; James ;   et al. | 2007-07-12 |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) App 20070160980 - Haeberli; Peter ;   et al. | 2007-07-12 |
RNA interference mediated of inhibition of influenza virus gene expression using short interfering nucleic acid (siNA) App 20070099858 - Jadhav; Vasant ;   et al. | 2007-05-03 |
Rna interference mediated inhibition of xiap gene expression using short interfering nucleic acid (sina) App 20070093437 - Chowrira; Bharat M. ;   et al. | 2007-04-26 |
Methods and reagents for oligonucleotide synthesis Grant 7,205,399 - Vargeese , et al. April 17, 2 | 2007-04-17 |
RNA interference mediated inhibition of 11 beta-hydroxysteroid dehydrogenase-1 (11 beta-HSD-1) gene expression using short interfering nucleic acid siNA App 20070049543 - McSwiggen; James ;   et al. | 2007-03-01 |
RNA interference mediated inhibition of gene expression using short interfering nucleic acid (siNA) App 20070042983 - Haeberli; Peter ;   et al. | 2007-02-22 |
Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R) App 20070042029 - Pavco; Pamela ;   et al. | 2007-02-22 |
Rna interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (sina) App 20070032441 - McSwiggen; James ;   et al. | 2007-02-08 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20070004665 - McSwiggen; James ;   et al. | 2007-01-04 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20070004667 - McSwiggen; James ;   et al. | 2007-01-04 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20070004663 - McSwiggen; James ;   et al. | 2007-01-04 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20070004664 - McSwiggen; James ;   et al. | 2007-01-04 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20060293272 - McSwiggen; James ;   et al. | 2006-12-28 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20060293271 - McSwiggen; James ;   et al. | 2006-12-28 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20060292691 - McSwiggen; James ;   et al. | 2006-12-28 |
RNA interference mediated inhibition of respiratory syncytial virus (RSV) expression using short interfering nucleic acid (siNA) App 20060287267 - Vaish; Narendra K. ;   et al. | 2006-12-21 |
RNA interference mediated ihibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20060287266 - McSwiggen; James ;   et al. | 2006-12-21 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20060281175 - McSwiggen; James ;   et al. | 2006-12-14 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20060275903 - McSwiggen; James ;   et al. | 2006-12-07 |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) App 20060276635 - McSwiggen; James ;   et al. | 2006-12-07 |
RNA interference mediated treatment of polyglutamine (polyQ) repeat expansion diseases using short interfering nucleic acid (siNA) App 20060270623 - McSwiggen; James | 2006-11-30 |
Conjugates and compositions for cellular delivery Grant 7,109,165 - Matulic-Adamic , et al. September 19, 2 | 2006-09-19 |
Antibodies having specificity for 2'-C-allyl nucleic acids Grant 7,071,311 - Radka , et al. July 4, 2 | 2006-07-04 |
Synthesis, deprotection, analysis and purification of RNA and ribozymes Grant 7,041,817 - Usman , et al. May 9, 2 | 2006-05-09 |
Enzymatic nucleic acid-mediated treatment of ocular diseases or conditions related to levels of vascular endothelial growth factor receptor (VEGF-R) Grant 7,034,009 - Pavco , et al. April 25, 2 | 2006-04-25 |
Method for the chemical synthesis of oligonucleotides Grant 6,995,259 - Vargeese , et al. February 7, 2 | 2006-02-07 |
Deprotection and purification of oligonucleotides and their derivatives Grant 6,989,442 - Vargeese January 24, 2 | 2006-01-24 |
Chemical synthesis of methoxy nucleosides Grant 6,972,330 - Beigelman , et al. December 6, 2 | 2005-12-06 |
Polymerase III-based expression of therapeutic RNAS Grant 6,852,535 - Thompson February 8, 2 | 2005-02-08 |
Non-nucleotide containing RNA Grant 6,849,726 - Usman , et al. February 1, 2 | 2005-02-01 |
Nucleic acid catalysts with endonuclease activity Grant 6,831,171 - Breaker , et al. December 14, 2 | 2004-12-14 |
2'-O-alkylthioalkyl and 2'-C-alkylthioalkyl-containing nucleic acids Grant 6,818,759 - Beigelman , et al. November 16, 2 | 2004-11-16 |
Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor Grant 6,818,447 - Pavco , et al. November 16, 2 | 2004-11-16 |
Xylofuranosly-containing nucleoside phosphoramidites and polynucleotides Grant 6,797,815 - Matulic-Adamic , et al. September 28, 2 | 2004-09-28 |
Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives Grant 6,686,463 - Beigelman , et al. February 3, 2 | 2004-02-03 |
Nucleic acid molecules with novel chemical compositions capable of modulating gene expression Grant 6,673,611 - Thompson , et al. January 6, 2 | 2004-01-06 |
Deprotection of RNA Grant 6,673,918 - Bellon , et al. January 6, 2 | 2004-01-06 |
Synthesis, deprotection, analysis and purification of RNA and ribozymes Grant 6,649,751 - Usman , et al. November 18, 2 | 2003-11-18 |
Enzymatic nucleic acid treatment of diseases of conditions related to levels of epidermal growth factor receptors Grant 6,623,962 - Akhtar , et al. September 23, 2 | 2003-09-23 |
Delivery of nucleic acids by porphyrins Grant 6,620,805 - Takle , et al. September 16, 2 | 2003-09-16 |
Purification of oligomers Grant 6,620,926 - Sproat September 16, 2 | 2003-09-16 |
Oligoribonucleotides with enzymatic activity Grant 6,617,438 - Beigelman , et al. September 9, 2 | 2003-09-09 |