Patent | Date |
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Compositions And Methods For Modulating Ttr Expression App 20220275365 - Prakash; Thazha P. ;   et al. | 2022-09-01 |
Modified CRISPR RNA and modified single CRISPR RNA and uses thereof Grant 11,414,657 - Rahdar , et al. August 16, 2 | 2022-08-16 |
Angiotensin Ii Type 1 Receptor Targeted Oligonucleotides And Uses Thereof App 20220243210 - Mullick; Adam ;   et al. | 2022-08-04 |
Compositions and methods for modulating growth hormone receptor expression Grant 11,312,964 - Prakash , et al. April 26, 2 | 2022-04-26 |
Conjugated antisense compounds and their use Grant 11,299,736 - Prakash , et al. April 12, 2 | 2022-04-12 |
Compositions and methods for modulating Ataxin 3 expression Grant 11,293,025 - Rigo , et al. April 5, 2 | 2022-04-05 |
Compounds and Methods for Use in Dystrophin Transcript App 20220081689 - Rigo; Frank ;   et al. | 2022-03-17 |
Compounds And Methods For Modulation Of Smn2 App 20220073914 - Rigo; Frank ;   et al. | 2022-03-10 |
5' modified nucleosides and oligomeric compounds prepared therefrom Grant 11,268,094 - Prakash , et al. March 8, 2 | 2022-03-08 |
Compounds And Methods For Modulating Smn2 App 20220064638 - Rigo; Frank ;   et al. | 2022-03-03 |
Compounds and methods for modulating C90RF72 Grant 11,260,073 - Prakash , et al. March 1, 2 | 2022-03-01 |
Oligomer-conjugate Complexes And Their Use App 20220025370 - Prakash; Thazha P. ;   et al. | 2022-01-27 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression App 20210395734 - Prakash; Thazha P. ;   et al. | 2021-12-23 |
GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof App 20210346509 - Monia; Brett P. ;   et al. | 2021-11-11 |
Compounds and Methods for Modulation of Transcript Processing App 20210315918 - Prakash; Thazha P. ;   et al. | 2021-10-14 |
Compositions and Methods for Modulating PKK Expression App 20210277401 - Prakash; Thazha P. ;   et al. | 2021-09-09 |
Oligomer-conjugate complexes and their use Grant 11,104,899 - Prakash , et al. August 31, 2 | 2021-08-31 |
Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom Grant 11,084,844 - Prakash , et al. August 10, 2 | 2021-08-10 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20210207146 - Prakash; Thazha P. ;   et al. | 2021-07-08 |
Compositions And Methods App 20210130823 - Prakash; Thazha P. ;   et al. | 2021-05-06 |
Modulation Of Frataxin Expression App 20210087559 - RIGO; Frank ;   et al. | 2021-03-25 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION App 20210087566 - PRAKASH; Thazha P. ;   et al. | 2021-03-25 |
Conjugated Antisense Compounds And Their Use App 20210052631 - Prakash; Thazha P. ;   et al. | 2021-02-25 |
Conjugated Antisense Compounds And Their Use App 20210054017 - Seth; Punit P. ;   et al. | 2021-02-25 |
Compositions and methods for modulating apolipoprotein C-III expression Grant 10,927,372 - Prakash , et al. February 23, 2 | 2021-02-23 |
Compositions And Methods For Modulating Ttr Expression App 20210024923 - Prakash; Thazha P. ;   et al. | 2021-01-28 |
Compositions and methods for modulating apolipoprotein (a) expression Grant 10,883,104 - Prakash , et al. January 5, 2 | 2021-01-05 |
Compositions and methods for modulating angiopoietin-like 3 expression Grant 10,875,884 - Prakash , et al. December 29, 2 | 2020-12-29 |
5' Modified Nucleosides And Oligomeric Compounds Prepared Therefrom App 20200385722 - Prakash; Thazha P. ;   et al. | 2020-12-10 |
Conjugated antisense compounds and their use Grant 10,844,379 - Prakash , et al. November 24, 2 | 2020-11-24 |
Compositions And Methods For Modulating Ataxin 3 Expression App 20200325473 - RIGO; Frank ;   et al. | 2020-10-15 |
Compositions and methods for modulating growth hormone receptor expression Grant 10,793,862 - Prakash , et al. October 6, 2 | 2020-10-06 |
Single-Stranded RNAI Oligonucleotides Targeting APOC-III App 20200270609 - Prakash; Thazha P. ;   et al. | 2020-08-27 |
Glp-1 Receptor Ligand Moiety Conjugated Oligonucleotides And Uses Thereof App 20200268898 - MONIA; Brett P. ;   et al. | 2020-08-27 |
Method for synthesis of reactive conjugate clusters Grant 10,751,419 - Migawa , et al. A | 2020-08-25 |
Compounds and methods for detecting oligonucleotides Grant 10,752,940 - Greenlee , et al. A | 2020-08-25 |
Compositions And Methods For Modulating Hbv Expression App 20200224198 - PRAKASH; Thazha P. ;   et al. | 2020-07-16 |
Compositions and methods for modulating TTR expression Grant 10,683,499 - Prakash , et al. | 2020-06-16 |
5' modified nucleosides and oligomeric compounds prepared therefrom Grant 10,676,738 - Prakash , et al. | 2020-06-09 |
Compositions And Methods For Enhanced Intestinal Absorption Of Conjugated Oligomeric Compounds App 20200157548 - Prakash; Thazha P. ;   et al. | 2020-05-21 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20200123551 - Prakash; Thazha P. ;   et al. | 2020-04-23 |
Conjugated antisense compounds and their use Grant 10,570,169 - Seth , et al. Feb | 2020-02-25 |
Compositions And Methods For Modulating Pkk Expression App 20200056185 - Prakash; Thazha P. ;   et al. | 2020-02-20 |
Compositions And Methods For Modulating Complement Factor B Expression App 20200048638 - Prakash; Thazha P. ;   et al. | 2020-02-13 |
Compositions and methods for modulating Ataxin 3 expression Grant 10,533,175 - Rigo , et al. Ja | 2020-01-14 |
Modified Crispr Rna And Uses Thereof App 20190382751 - Radhar; Meghdad ;   et al. | 2019-12-19 |
Conjugated Antisense Compounds And Their Use App 20190367914 - Prakash; Thazha P. ;   et al. | 2019-12-05 |
Compounds And Methods For Use In Dystrophin Transcript App 20190330626 - Rigo; Frank ;   et al. | 2019-10-31 |
Compounds And Methods For Modulation Of Smn2 App 20190323006 - Rigo; Frank ;   et al. | 2019-10-24 |
Compounds And Methods For Modulation Of Transcript Processing App 20190321387 - Prakash; Thazha P. ;   et al. | 2019-10-24 |
Methods and compounds useful in conditions related to repeat expansion Grant 10,435,430 - Prakash , et al. O | 2019-10-08 |
Method For Synthesis Of Reactive Conjugate Clusters App 20190209694 - Migawa; Michael T. ;   et al. | 2019-07-11 |
Oligomer-conjugate Complexes And Their Use App 20190136234 - Prakash; Thazha P. ;   et al. | 2019-05-09 |
GLP-1 Receptor Ligand Moiety Conjugated Oligonucleotides and Uses Thereof App 20190134214 - Monia; Brett P. ;   et al. | 2019-05-09 |
Compositions and methods for modulating complement factor B expression Grant 10,280,423 - Prakash , et al. | 2019-05-07 |
Single-stranded Rnai Oligonucleotides Targeting Apoc-iii App 20190127737 - Prakash; Thazha P. ;   et al. | 2019-05-02 |
Compositions And Methods For Modulating Hbv Expression App 20190055554 - Prakash; Thazha P. ;   et al. | 2019-02-21 |
Compositions And Methods For Modulating Angiopoietin-like 3 Expression App 20190016748 - Prakash; Thazha P. ;   et al. | 2019-01-17 |
Modified Nucleosides, Analogs Thereof And Oligomeric Compounds Prepared Therefrom App 20180371005 - Prakash; Thazha P. ;   et al. | 2018-12-27 |
Compounds And Methods For Modulating C90rf72 App 20180318330 - PRAKASH; Thazha P. ;   et al. | 2018-11-08 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20180320188 - Prakash; Thazha P. ;   et al. | 2018-11-08 |
Targeted Therapeutic Nucleosides And Their Use App 20180296684 - Seth; Punit P. ;   et al. | 2018-10-18 |
Method for synthesis of reactive conjugate clusters Grant 10,098,959 - Migawa , et al. October 16, 2 | 2018-10-16 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION App 20180273953 - Prakash; Thazha P. ;   et al. | 2018-09-27 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression App 20180273952 - Prakash; Thazha P. ;   et al. | 2018-09-27 |
Compositions And Methods For Modulating Ataxin 3 Expression App 20180258425 - RIGO; Frank ;   et al. | 2018-09-13 |
Compositions And Methods For Enhanced Intestinal Absorption Of Conjugated Oligomeric Compounds App 20180245084 - Prakash; Thazha P. ;   et al. | 2018-08-30 |
Oligomer-conjugate complexes and their use Grant 10,023,861 - Prakash , et al. July 17, 2 | 2018-07-17 |
Modified Crispr Rna And Modified Single Crispr Rna And Uses Thereof App 20180179521 - Rahdar; Meghdad ;   et al. | 2018-06-28 |
Compositions and methods for modulating growth hormone receptor expression Grant 9,994,855 - Prakash , et al. June 12, 2 | 2018-06-12 |
Methods and compounds useful in conditions related to repeat expansion Grant 9,976,138 - Prakash , et al. May 22, 2 | 2018-05-22 |
Compositions and methods for modulating angiopoietin-like 3 expression Grant 9,957,292 - Prakash , et al. May 1, 2 | 2018-05-01 |
Compositions and methods for modulating apolipoprotein (a) expression Grant 9,957,504 - Prakash , et al. May 1, 2 | 2018-05-01 |
Targeted therapeutic nucleosides and their use Grant 9,943,604 - Seth , et al. April 17, 2 | 2018-04-17 |
Compositions and methods for modulating apolipoprotein C-III expression Grant 9,932,581 - Prakash , et al. April 3, 2 | 2018-04-03 |
Compositions and methods for modulating HBV expression Grant 9,932,580 - Prakash , et al. April 3, 2 | 2018-04-03 |
Compositions And Methods For Modulating Ttr Expression App 20180044676 - Prakash; Thazha P. ;   et al. | 2018-02-15 |
Compositions And Methods App 20180002693 - Prakash; Thazha P. ;   et al. | 2018-01-04 |
Conjugated Antisense Compounds And Their Use App 20170355727 - Seth; Punit P. ;   et al. | 2017-12-14 |
Phosphorous-linked oligomeric compounds and their use in gene modulation Grant 9,771,578 - Baker , et al. September 26, 2 | 2017-09-26 |
Gapped oligomeric compounds comprising 5'-modified deoxyribonucleosides in the gap and uses thereof Grant 9,752,142 - Oestergaard , et al. September 5, 2 | 2017-09-05 |
Oligomeric compounds and methods Grant 9,738,895 - Swayze , et al. August 22, 2 | 2017-08-22 |
5'-end derivatives Grant 9,725,479 - Manoharan , et al. August 8, 2 | 2017-08-08 |
Compositions and methods Grant 9,714,421 - Prakash , et al. July 25, 2 | 2017-07-25 |
Compositions And Methods For Modulating Pkk Expression App 20170183661 - Prakash; Thazha P. ;   et al. | 2017-06-29 |
Nucleoside Derivatives As Inhibitors Of Rna-dependent Rna Viral Polyermase App 20170183373 - Bhat; Balkrishen ;   et al. | 2017-06-29 |
Compositions And Methods For Modulating Growth Hormone Receptor Expression App 20170166899 - Prakash; Thazha P. ;   et al. | 2017-06-15 |
Compositions And Methods For Modulating Complement Factor B Expression App 20170159055 - Prakash; Thazha P. ;   et al. | 2017-06-08 |
Compositions And Methods For Enhanced Intestinal Absorption Of Conjugated Oligomeric Compounds App 20170145424 - Prakash; Thazha P. ;   et al. | 2017-05-25 |
Linkage Modified Gapped Oligomeric Compounds And Uses Thereof App 20170130224 - Oestergaard; Michael ;   et al. | 2017-05-11 |
Method For Synthesis Of Reactive Conjugate Clusters App 20170043025 - Migawa; Michael T. ;   et al. | 2017-02-16 |
Targeted Therapeutic Nucleosides And Their Use App 20160354476 - Seth; Punit P. ;   et al. | 2016-12-08 |
Compounds And Methods For Detecting Oligonucleotides App 20160281148 - Greenlee; Sarah ;   et al. | 2016-09-29 |
Oligomeric compounds comprising tricyclic nucleosides and methods for their use Grant 9,428,750 - Swayze , et al. August 30, 2 | 2016-08-30 |
Compositions And Methods For Modulating Angiopoietin-like 3 Expression App 20160194349 - Prakash; Thazha P. ;   et al. | 2016-07-07 |
Compositions and methods for modulating angiopoietin-like 3 expression Grant 9,382,540 - Prakash , et al. July 5, 2 | 2016-07-05 |
Methods And Compounds Useful In Conditions Related To Repeat Expansion App 20160159846 - Prakash; Thazha P. ;   et al. | 2016-06-09 |
Compositions And Methods For Modulation Of Target Nucleic Acids App 20160122761 - Prakash; Thazha P. ;   et al. | 2016-05-05 |
Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom Grant 9,321,799 - Prakash , et al. April 26, 2 | 2016-04-26 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION App 20160090596 - Prakash; Thazha P. ;   et al. | 2016-03-31 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression App 20160090595 - Prakash; Thazha P. ;   et al. | 2016-03-31 |
Phosphorous-linked Oligomeric Compounds And Their Use In Gene Modulation App 20160076031 - Baker; Brenda F. ;   et al. | 2016-03-17 |
Compositions And Methods For Modulating Hbv Expression App 20160076030 - Prakash; Thazha P. ;   et al. | 2016-03-17 |
Compositions And Methods App 20160076032 - Prakash; Thazha P. ;   et al. | 2016-03-17 |
5' Modified Nucleosides And Oligomeric Compounds Prepared Therefrom App 20160046939 - Prakash; Thazha P. ;   et al. | 2016-02-18 |
Conjugated Antisense Compounds And Their Use App 20160017323 - Prakash; Thazha P. ;   et al. | 2016-01-21 |
5'-substituted bicyclic nucleosides and oligomeric compounds prepared therefrom Grant 9,193,752 - Migawa , et al. November 24, 2 | 2015-11-24 |
Conjugated antisense compounds and their use Grant 9,181,549 - Prakash , et al. November 10, 2 | 2015-11-10 |
Compositions and methods for modulating apolipoprotein (a) expression Grant 9,181,550 - Prakash , et al. November 10, 2 | 2015-11-10 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20150315579 - Bhat; Balkrishen ;   et al. | 2015-11-05 |
Compositions And Methods For Modulating Angiopoietin-like 3 Expression App 20150315594 - Prakash; Thazha P. ;   et al. | 2015-11-05 |
Compositions and methods for modulating apolipoprotein C-III expression Grant 9,163,239 - Prakash , et al. October 20, 2 | 2015-10-20 |
Modified 5' diphosphate nucleosides and oligomeric compounds prepared therefrom Grant 9,156,873 - Prakash , et al. October 13, 2 | 2015-10-13 |
Compositions and methods for modulating HBV expression Grant 9,145,558 - Prakash , et al. September 29, 2 | 2015-09-29 |
Oligomeric Compounds Comprising Tricyclic Nucelosides And Methods For Their Use App 20150259681 - Swayze; Eric E. ;   et al. | 2015-09-17 |
5' modified nucleosides and oligomeric compounds prepared therefrom Grant 9,127,033 - Prakash , et al. September 8, 2 | 2015-09-08 |
Conjugated antisense compounds and their use Grant 9,127,276 - Prakash , et al. September 8, 2 | 2015-09-08 |
2' and 5' modified monomers and oligonucleotides Grant 9,102,938 - Rajeev , et al. August 11, 2 | 2015-08-11 |
Compositions And Methods For Modulating Hbv Expression App 20150176007 - Prakash; Thazha P. ;   et al. | 2015-06-25 |
Oligomeric Compounds And Methods App 20150167006 - Swayze; Eric E. ;   et al. | 2015-06-18 |
Modified Nucleosides, Analogs Thereof And Oligomeric Compounds Prepared Therefrom App 20150159163 - Prakash; Thazha P. ;   et al. | 2015-06-11 |
Substituted 2'-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom Grant 9,029,335 - Prakash , et al. May 12, 2 | 2015-05-12 |
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION App 20150126720 - Prakash; Thazha P. ;   et al. | 2015-05-07 |
Conjugated Antisense Compounds And Their Use App 20150126718 - Prakash; Thazha P. ;   et al. | 2015-05-07 |
Compositions And Methods For Modulating Apolipoprotein C-iii Expression App 20150126719 - Prakash; Thazha P. ;   et al. | 2015-05-07 |
5' And 2' Bis-substituted Nucleosides And Oligomeric Compounds Prepared Therefrom App 20150126725 - Swayze; Eric E. ;   et al. | 2015-05-07 |
Tetrahydropyran nucleic acid analogs Grant 9,005,906 - Swayze , et al. April 14, 2 | 2015-04-14 |
Oligomeric compounds comprising tricyclic nucelosides and methods for their use Grant 8,993,528 - Swayze , et al. March 31, 2 | 2015-03-31 |
Modified nucleosides, analogs thereof and oligomeric compounds prepared therefrom Grant 8,993,738 - Prakash , et al. March 31, 2 | 2015-03-31 |
Oligomeric compounds and methods Grant 8,987,435 - Swayze , et al. March 24, 2 | 2015-03-24 |
Oligomer-conjugate Complexes And Their Use App 20150018540 - Prakash; Thazha P. ;   et al. | 2015-01-15 |
Compositions And Methods For Optimizing Cleavage Of Rna By Rnase H App 20150011001 - Migawa; Michael T. ;   et al. | 2015-01-08 |
Conjugated Antisense Compounds And Their Use App 20140343123 - Prakash; Thazha P. ;   et al. | 2014-11-20 |
5' and 2' BIS-substituted nucleosides and oligomeric compounds prepared therefrom Grant 8,883,752 - Swayze , et al. November 11, 2 | 2014-11-11 |
Tetrahydropyran Nucleic Acid Analogs App 20140315979 - Swayze; Eric E. ;   et al. | 2014-10-23 |
Methods And Compounds Useful In Conditions Related To Repeat Expansion App 20140316121 - Prakash; Thazha P. ;   et al. | 2014-10-23 |
Nucleoside Derivatives As Inhibitors Of Rna-dependent Rna Viral Polymerase App 20140309412 - Bhat; Balkrishen ;   et al. | 2014-10-16 |
Gapped Oligomeric Compounds Comprising 5'-modified Deoxyribonucleosides In The Gap And Uses Thereof App 20140309279 - Oestergaard; Michael ;   et al. | 2014-10-16 |
Linkage Modified Gapped Oligomeric Compounds And Uses Thereof App 20140303235 - Oestergaard; Michael ;   et al. | 2014-10-09 |
Substituted 2'-amino and 2'-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom Grant 8,846,637 - Seth , et al. September 30, 2 | 2014-09-30 |
Tetrahydropyran nucleic acid analogs Grant 8,796,437 - Swayze , et al. August 5, 2 | 2014-08-05 |
Compositions and methods for optimizing cleavage of RNA by RNase H Grant 8,790,919 - Migawa , et al. July 29, 2 | 2014-07-29 |
Substituted 2'-thio-bicyclic Nucleosides And Oligomeric Compounds Prepared Therefrom App 20140106451 - Prakash; Thazha P. ;   et al. | 2014-04-17 |
5'-end Derivatives App 20130323836 - Manoharan; Muthiah ;   et al. | 2013-12-05 |
Conformationally Restricted Dinucleotide Monomers And Oligonucleotides App 20130260460 - Lackey; Jeremy ;   et al. | 2013-10-03 |
Tetrahydropyran nucleic acid analogs Grant 8,536,320 - Prakash , et al. September 17, 2 | 2013-09-17 |
Tetrahydropyran Nucleic Acid Analogs App 20130211064 - Swayze; Eric E. ;   et al. | 2013-08-15 |
2' And 5' Modified Monomers And Oligonucleotides App 20130203836 - Rajeev; Kallanthottathil G. ;   et al. | 2013-08-08 |
Oligomeric Compounds Comprising Tricyclic Nucelosides And Methods For Their Use App 20130197062 - Swayze; Eric E. ;   et al. | 2013-08-01 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase Grant 8,481,712 - Bhat , et al. July 9, 2 | 2013-07-09 |
Lipid Formulated Single Stranded Rna App 20130156845 - Manoharan; Muthiah ;   et al. | 2013-06-20 |
Substituted 2'-amino And 2'-thio-bicyclic Nucleosides And Oligomeric Compounds Prepared Therefrom App 20130131147 - Seth; Punit P. ;   et al. | 2013-05-23 |
Tetrahydropyran nucleic acid analogs Grant 8,440,803 - Swayze , et al. May 14, 2 | 2013-05-14 |
5' Modified Nucleosides And Oligomeric Compounds Prepared Therefrom App 20130116420 - Prakash; Thazha P. ;   et al. | 2013-05-09 |
Modified 5' Diphosphate Nucleosides And Oligomeric Compounds Prepared Therefrom App 20130109850 - Prakash; Thazha P. ;   et al. | 2013-05-02 |
Oligomeric compounds comprising tricyclic nucelosides and methods for their use Grant 8,426,378 - Swayze , et al. April 23, 2 | 2013-04-23 |
Modified Nucleosides, Analogs Thereof And Oligomeric Compounds Prepared Therefrom App 20130084576 - Prakash; Thazha P. ;   et al. | 2013-04-04 |
Positionally modified siRNA constructs Grant 8,394,947 - Bhat , et al. March 12, 2 | 2013-03-12 |
5'-substituted Bicyclic Nucleosides And Oligomeric Compounds Prepared Therefrom App 20130041144 - Migawa; Michael T. ;   et al. | 2013-02-14 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20130035369 - Bhat; Balkrishen ;   et al. | 2013-02-07 |
N-substituted-aminomethylene bridged bicyclic nucleic acid analogs Grant 8,278,425 - Prakash , et al. October 2, 2 | 2012-10-02 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase App 20120165515 - Bhat; Balkrishen ;   et al. | 2012-06-28 |
Tetrahydropyran Nucleic Acid Analogs App 20120071645 - Swayze; Eric E. ;   et al. | 2012-03-22 |
Methods Of Using Oligomeric Compounds Comprising 2'-substituted Nucleosides App 20120059045 - Prakash; Thazha P. ;   et al. | 2012-03-08 |
Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation Grant 8,124,745 - Allerson , et al. February 28, 2 | 2012-02-28 |
Tetrahydropyran Nucleic Acid Analogs App 20120022014 - Prakash; Thazha P. ;   et al. | 2012-01-26 |
Oligomeric Compounds And Methods App 20120021515 - Swayze; Eric E. ;   et al. | 2012-01-26 |
Tetrahydropyran nucleic acid analogs Grant 8,088,904 - Swayze , et al. January 3, 2 | 2012-01-03 |
Oligomeric Compounds And Methods App 20110313019 - Swayze; Eric E. ;   et al. | 2011-12-22 |
5' And 2' Bis-substituted Nucleosides And Oligomeric Compounds Prepared Therefrom App 20110269821 - Swayze; Eric E. ;   et al. | 2011-11-03 |
Oligomeric compounds comprising 4'-thionucleosides for use in gene modulation Grant 7,939,677 - Bhat , et al. May 10, 2 | 2011-05-10 |
Oligomeric Compounds Comprising Tricyclic Nucelosides And Methods For Their Use App 20110092570 - Swayze; Eric E. ;   et al. | 2011-04-21 |
2'-substituted oligomeric compounds and compositions for use in gene modulations Grant 7,919,612 - Baker , et al. April 5, 2 | 2011-04-05 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20110046206 - Bhat; Balkrishen ;   et al. | 2011-02-24 |
Oligomeric compounds comprising 4'-thionucleosides for use in gene modulation Grant 7,875,733 - Bhat , et al. January 25, 2 | 2011-01-25 |
Oligomeric Compounds Comprising 4'-thionucleosides For Use In Gene Modulation App 20100324277 - Bhat; Balkrishen ;   et al. | 2010-12-23 |
2'-Fluoro substituted oligomeric compounds and compositions for use in gene modulations Grant 7,812,149 - Prakash , et al. October 12, 2 | 2010-10-12 |
N-Substituted-Aminomethylene Bridged Bicyclic Nucleic Acid Analogs App 20100249211 - Prakash; Thazha P. ;   et al. | 2010-09-30 |
Polycyclic Sugar Surrogate-containing Oligomeric Compounds And Compositions For Use In Gene Modulation App 20100216982 - Allerson; Charles ;   et al. | 2010-08-26 |
Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation Grant 7,696,345 - Allerson , et al. April 13, 2 | 2010-04-13 |
Conjugated Double Strand Compositions For Use In Gene Modulation App 20090306178 - Bhat; Balkrishen ;   et al. | 2009-12-10 |
Pyrrolidinyl Groups For Attaching Conjugates To Oligomeric Compounds App 20090203132 - Swayze; Eric E. ;   et al. | 2009-08-13 |
Compounds and methods for synthesis of bicyclic nucleic acid analogs Grant 7,569,686 - Bhat , et al. August 4, 2 | 2009-08-04 |
Tetrahydropyran Nucleic Acid Analogs App 20090092981 - Swayze; Eric E. ;   et al. | 2009-04-09 |
Double Strand Compositions Comprising Differentially Modified Strands for Use in Gene Modulation App 20090048192 - Bhat; Balkrishen ;   et al. | 2009-02-19 |
Chimeric Gapped Oligomeric Compounds App 20080261904 - Bhat; Balkrishen ;   et al. | 2008-10-23 |
Compositions and Methods For Optimizing Cleavage of Rna By Rnase H App 20080207541 - Migawa; Michael T. ;   et al. | 2008-08-28 |
Positionally Modified Sirna Constructs App 20080146788 - Bhat; Balkrishen ;   et al. | 2008-06-19 |
Double Strand Compositions Comprising Differentially Modified Strands for Use in Gene Modulation App 20080119427 - Bhat; Balkrishen ;   et al. | 2008-05-22 |
Nucleoside derivatives as inhibitors of rna-dependent RNA viral polymerase App 20070275912 - Bhat; Balkrishen ;   et al. | 2007-11-29 |
Oligomeric Compounds That Facilitate Risc Loading App 20070275921 - Swayze; Eric E. ;   et al. | 2007-11-29 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070185047 - Bhat; Balkrishen ;   et al. | 2007-08-09 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070185046 - Bhat; Balkrishen ;   et al. | 2007-08-09 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070179109 - Bhat; Balkrishen ;   et al. | 2007-08-02 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070179106 - Bhat; Balkrishen ;   et al. | 2007-08-02 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070179108 - Bhat; Balkrishen ;   et al. | 2007-08-02 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070173474 - Bhat; Balkrishen ;   et al. | 2007-07-26 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070172948 - Bhat; Balkrishen ;   et al. | 2007-07-26 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070173475 - Bhat; Balkrishen ;   et al. | 2007-07-26 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070166734 - Bhat; Balkrishen ;   et al. | 2007-07-19 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070167390 - Bhat; Balkrishen ;   et al. | 2007-07-19 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070167392 - Bhat; Balkrishen ;   et al. | 2007-07-19 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070167391 - Bhat; Balkrishen ;   et al. | 2007-07-19 |
Double Strand Compositions Comprising Differentially Modified Strands For Use In Gene Modulation App 20070123484 - Bhat; Balkrishen ;   et al. | 2007-05-31 |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase App 20060264389 - Bhat; Balkrishen ;   et al. | 2006-11-23 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase Grant 7,125,855 - Bhat , et al. October 24, 2 | 2006-10-24 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase App 20060205686 - Bhat; Balkrishen ;   et al. | 2006-09-14 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase Grant 7,105,499 - Carroll , et al. September 12, 2 | 2006-09-12 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase App 20050272676 - Bhat, Balkrishen ;   et al. | 2005-12-08 |
Methods of modulating pharmacokinetics of oligonucleotides Grant 6,921,812 - Prakash , et al. July 26, 2 | 2005-07-26 |
Guanidinium functionalized intermediates Grant 6,914,148 - Manoharan , et al. July 5, 2 | 2005-07-05 |
4'-thionucleosides and oligomeric compounds App 20050130923 - Bhat, Balkrishen ;   et al. | 2005-06-16 |
Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation App 20050118605 - Baker, Brenda F. ;   et al. | 2005-06-02 |
Phosphorous-linked oligomeric compounds and their use in gene modulation App 20050042647 - Baker, Brenda F. ;   et al. | 2005-02-24 |
Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation App 20050037370 - Baker, Brenda F. ;   et al. | 2005-02-17 |
Non-phosphorous-linked oligomeric compounds and their use in gene modulation App 20050032067 - Prakash, Thazha P. ;   et al. | 2005-02-10 |
Sugar and backbone-surrogate-containing oligomeric compounds and compositions for use in gene modulation App 20050032068 - Prakash, Thazha P. ;   et al. | 2005-02-10 |
Oligomeric compounds having modified bases for binding to adenine and guanine and their use in gene modulation App 20050032069 - Manoharan, Muthiah ;   et al. | 2005-02-10 |
Phosphorous-linked oligomeric compounds and their use in gene modulation App 20040254358 - Manoharan, Muthiah ;   et al. | 2004-12-16 |
2'-substituted oligomeric compounds and compositions for use in gene modulations App 20040171033 - Baker, Brenda F. ;   et al. | 2004-09-02 |
2'-Fluoro substituted oligomeric compounds and compositions for use in gene modulations App 20040171029 - Prakash, Thazha P. ;   et al. | 2004-09-02 |
Non-phosphorous-linked oligomeric compounds and their use in gene modulation App 20040171032 - Baker, Brenda F. ;   et al. | 2004-09-02 |
Phosphorous-linked oligomeric compounds and their use in gene modulation App 20040171028 - Baker, Brenda F. ;   et al. | 2004-09-02 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase of hepatitis C virus Grant 6,777,395 - Bhat , et al. August 17, 2 | 2004-08-17 |
Cross-linked oligomeric compounds and their use in gene modulation App 20040147470 - Manoharan, Muthiah ;   et al. | 2004-07-29 |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase App 20040110717 - Carroll, Steven S. ;   et al. | 2004-06-10 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase App 20040072788 - Bhat, Balkrishen ;   et al. | 2004-04-15 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase App 20040067901 - Bhat, Balkrishen ;   et al. | 2004-04-08 |
Compounds and oligomeric compounds comprising novel nucleobases App 20040033973 - Manoharan, Muthiah ;   et al. | 2004-02-19 |
Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefrom Grant 6,639,062 - Manoharan , et al. October 28, 2 | 2003-10-28 |
Regioselective synthesis of 2'-O-modified nucleosides Grant 6,624,294 - Kawasaki , et al. September 23, 2 | 2003-09-23 |
Nuclease resistant chimeric oligonucleotides App 20030175906 - Manoharan, Muthiah ;   et al. | 2003-09-18 |
Nuclease resistant chimeric oligonucleotides App 20030158403 - Manoharan, Muthiah ;   et al. | 2003-08-21 |
Guanidinium functionalized nucleotides and precursors thereof Grant 6,593,466 - Manoharan , et al. July 15, 2 | 2003-07-15 |
Guanidinium functionalized oligomers and methods App 20030092046 - Manoharan, Muthiah ;   et al. | 2003-05-15 |
Aminooxy-modified Nucleosidic Compounds And Oligomeric Compounds Prepared Therefrom App 20030088079 - MANOHARAN, MUTHIAH ;   et al. | 2003-05-08 |
Regioselective synthesis of 2'-O-modified nucleosides App 20030078415 - Kawasaki, Andrew M. ;   et al. | 2003-04-24 |
Guanidinium functionalized oligonucleotides and method/synthesis Grant 6,534,639 - Manoharan , et al. March 18, 2 | 2003-03-18 |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase App 20020147160 - Bhat, Balkrishen ;   et al. | 2002-10-10 |
Regioselective synthesis of 2'-O-modified nucleosides Grant 6,403,779 - Kawasaki , et al. June 11, 2 | 2002-06-11 |
Aminooxy-modified oligonucleotides and methods for making same Grant 6,172,209 - Manoharan , et al. January 9, 2 | 2001-01-09 |
2'-O-acetamido modified monomers and oligomers Grant 6,147,200 - Manoharan , et al. November 14, 2 | 2000-11-14 |