Heartlein; Michael
Patent Applications and Registrations
Patent applications and USPTO patent grants for Heartlein; Michael.The latest application filed is for "compositions and methods for mrna delivery".
Company Profile
81.102.176
- Heartlein; Michael - Lexington MA
- Heartlein; Michael - Boxborough MA
- Heartlein; Michael - Cambridge MA
- Heartlein; Michael - Boxbourugh MA
Patent Activity
| Patent | Date |
|---|---|
| Ribonucleic acids with 4'-thio-modified nucleotides and related methods Grant 11,447,520 - DeRosa , et al. September 20, 2 | 2022-09-20 |
| Biodegradable lipids for delivery of nucleic acids Grant 11,433,144 - DeRosa , et al. September 6, 2 | 2022-09-06 |
| Polyanionic delivery of nucleic acids Grant 11,427,535 - Heartlein , et al. August 30, 2 | 2022-08-30 |
| COMPOSITIONS AND METHODS FOR mRNA DELIVERY App 20220249699 - Guild; Braydon Charles ; et al. | 2022-08-11 |
| Subcutaneous delivery of messenger RNA Grant 11,400,109 - Karve , et al. August 2, 2 | 2022-08-02 |
| Encapsulation Of Messenger Rna App 20220226255 - DeRosa; Frank ; et al. | 2022-07-21 |
| Pulmonary Delivery of MRNA to Non-lung Target Cells App 20220226236 - Heartlein; Michael ; et al. | 2022-07-21 |
| Macrocyclic Lipids App 20220226244 - Zhang; Yi ; et al. | 2022-07-21 |
| Mrna Therapy For Argininosuccinate Synthetase Deficiency App 20220218803 - Heartlein; Michael ; et al. | 2022-07-14 |
| mRNA therapy for phenylketonuria Grant 11,377,642 - DeRosa , et al. July 5, 2 | 2022-07-05 |
| Cleavable Lipids App 20220202718 - Guild; Braydon Charles ; et al. | 2022-06-30 |
| Novel Codon-Optimized CFTR MRNA App 20220193247 - Dias; Anusha ; et al. | 2022-06-23 |
| Quantitative assessment for cap efficiency of messenger RNA Grant 11,365,437 - Heartlein , et al. June 21, 2 | 2022-06-21 |
| Process of preparing mRNA-loaded lipid nanoparticles Grant 11,357,726 - Karve , et al. June 14, 2 | 2022-06-14 |
| Methods For Purification Of Messenger Rna App 20220170061 - Parella; Joseph ; et al. | 2022-06-02 |
| TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF CODON-OPTIMIZED mRNA ENCODING CFTR App 20220160827 - Heartlein; Michael ; et al. | 2022-05-26 |
| Lipid nanoparticle compositions and methods for mRNA delivery Grant 11,338,044 - Guild , et al. May 24, 2 | 2022-05-24 |
| Methods For Purification Of Messenger Rna App 20220135608 - DeRosa; Frank ; et al. | 2022-05-05 |
| Liver Specific Delivery Of Messenger Rna App 20220111075 - Guild; Braydon Charles ; et al. | 2022-04-14 |
| Liver Specific Delivery Of Messenger Rna App 20220111074 - Guild; Braydon Charles ; et al. | 2022-04-14 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20220111072 - Guild; Braydon Charles ; et al. | 2022-04-14 |
| Liver Specific Delivery Of Messenger Rna App 20220111076 - Guild; Braydon Charles ; et al. | 2022-04-14 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20220111071 - Guild; Braydon Charles ; et al. | 2022-04-14 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20220111070 - Guild; Braydon Charles ; et al. | 2022-04-14 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20220105201 - GUILD; BRAYDON CHARLES ; et al. | 2022-04-07 |
| Lipid nanoparticle compositions and methods for mRNA delivery Grant 11,291,734 - Guild , et al. April 5, 2 | 2022-04-05 |
| Composition and Methods for Treatment of Primary Ciliary Dyskinesia App 20220087935 - Dias; Anusha ; et al. | 2022-03-24 |
| Peg Lipidoid Compounds App 20220071905 - Karve; Shrirang ; et al. | 2022-03-10 |
| Multimeric Coding Nucleic Acid And Uses Thereof App 20220073944 - DeRosa; Frank ; et al. | 2022-03-10 |
| Composition and Methods for Treatment of Ornithine Transcarbamylase Deficiency App 20220072152 - Askew; Kim ; et al. | 2022-03-10 |
| mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES App 20220054602 - Guild; Braydon Charles ; et al. | 2022-02-24 |
| Nuclease resistant polynucleotides and uses thereof Grant 11,254,936 - Heartlein , et al. February 22, 2 | 2022-02-22 |
| Codon-optimized CFTR MRNA Grant 11,253,605 - Dias , et al. February 22, 2 | 2022-02-22 |
| Stereochemically Enriched Compositions For Delivery Of Nucleic Acids App 20220048867 - DeRosa; Frank ; et al. | 2022-02-17 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20220040330 - Guild; Braydon Charles ; et al. | 2022-02-10 |
| Cleavable lipids Grant 11,234,936 - Guild , et al. February 1, 2 | 2022-02-01 |
| Multi-peg Lipid Compounds App 20220016029 - Karve; Shrirang ; et al. | 2022-01-20 |
| MRNA therapy for argininosuccinate synthetase deficiency Grant 11,224,642 - Heartlein , et al. January 18, 2 | 2022-01-18 |
| Modification Of Rna-related Enzymes For Enhanced Production App 20220010347 - Strack-Logue; Bettina ; et al. | 2022-01-13 |
| Thioester Cationic Lipids App 20220008338 - Zhang; Yi ; et al. | 2022-01-13 |
| Mrna Therapy For Pompe Disease App 20210401951 - DeRosa; Frank ; et al. | 2021-12-30 |
| Pumpless Encapsulation Of Messenger Rna App 20210378962 - Karve; Shrirang ; et al. | 2021-12-09 |
| Dry Powder Formulations for Messenger RNA App 20210378977 - Karve; Shrirang ; et al. | 2021-12-09 |
| Biodegradable Lipids For Delivery Of Nucleic Acids App 20210369866 - DeRosa; Frank ; et al. | 2021-12-02 |
| Quantitative Assessment For Cap Efficiency Of Messenger Rna App 20210371900 - Heartlein; Michael ; et al. | 2021-12-02 |
| Lipid nanoparticle compositions and methods for mRNA delivery Grant 11,185,595 - Guild , et al. November 30, 2 | 2021-11-30 |
| Ice-based Lipid Nanoparticle Formulation For Delivery Of Mrna App 20210353761 - DeRosa; Frank ; et al. | 2021-11-18 |
| Treatment of cystic fibrosis by delivery of codon-optimized mRNA encoding CFTR Grant 11,173,190 - Heartlein , et al. November 16, 2 | 2021-11-16 |
| Methods for purification of messenger RNA Grant 11,174,500 - Parella , et al. November 16, 2 | 2021-11-16 |
| Composition and methods for treatment of ornithine transcarbamylase deficiency Grant 11,167,043 - Askew , et al. November 9, 2 | 2021-11-09 |
| Methods For Purification Of Messenger Rna App 20210324368 - Heartlein; Michael ; et al. | 2021-10-21 |
| MRNA for use in treatment of human genetic diseases Grant 11,135,274 - Guild , et al. October 5, 2 | 2021-10-05 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20210300755 - Guild; Braydon Charles ; et al. | 2021-09-30 |
| Multimeric coding nucleic acid and uses thereof Grant 11,124,804 - DeRosa , et al. September 21, 2 | 2021-09-21 |
| Stereochemically enriched compositions for delivery of nucleic acids Grant 11,104,652 - DeRosa , et al. August 31, 2 | 2021-08-31 |
| Quantitative assessment for cap efficiency of messenger RNA Grant 11,104,934 - Heartlein , et al. August 31, 2 | 2021-08-31 |
| PolyAnionic Delivery of Nucleic Acids App 20210261502 - Heartlein; Michael ; et al. | 2021-08-26 |
| Pulmonary delivery of mRNA to non-lung target cells Grant 11,090,264 - Heartlein , et al. August 17, 2 | 2021-08-17 |
| MRNA therapy for Pompe disease Grant 11,090,368 - DeRosa , et al. August 17, 2 | 2021-08-17 |
| Cationic Lipids Comprising a Steroidal Moiety App 20210220273 - Zhang; Yi ; et al. | 2021-07-22 |
| Subcutaneous Delivery of Messenger RNA App 20210220449 - Karve; Shrirang ; et al. | 2021-07-22 |
| Phosphoester Cationic Lipids App 20210213140 - Zhang; Yi ; et al. | 2021-07-15 |
| Methods for purification of messenger RNA Grant 11,059,841 - DeRosa , et al. July 13, 2 | 2021-07-13 |
| Methods And Compositions For Delivering Mrna Coded Antibodies App 20210206846 - Heartlein; Michael ; et al. | 2021-07-08 |
| Vitamin Cationic Lipids App 20210206739 - Zhang; Yi ; et al. | 2021-07-08 |
| Messenger Rna Therapy For The Treatment Of Ornithine Transcarbamylase Deficiency App 20210205421 - DeRosa; Frank ; et al. | 2021-07-08 |
| Lipid nanoparticle compositions and methods for mRNA delivery Grant 11,052,159 - Guild , et al. July 6, 2 | 2021-07-06 |
| Cns Delivery Of Mrna And Uses Thereof App 20210196633 - DeRosa; Frank ; et al. | 2021-07-01 |
| Messenger Rna Therapy For Treatment Of Articular Disease App 20210196820 - DeRosa; Frank ; et al. | 2021-07-01 |
| Messenger Rna Therapy For The Treatment Of Friedreich's Ataxia App 20210187122 - Heartlein; Michael ; et al. | 2021-06-24 |
| Methods For Purification of Messenger RNA App 20210180041 - DeRosa; Frank ; et al. | 2021-06-17 |
| Ice-based lipid nanoparticle formulation for delivery of mRNA Grant 11,013,812 - DeRosa , et al. May 25, 2 | 2021-05-25 |
| Modification of RNA-related enzymes for enhanced production Grant 10,995,354 - Strack-Logue , et al. May 4, 2 | 2021-05-04 |
| Methods For Purification of Messenger RNA App 20210123041 - Abysalh; Jonathan ; et al. | 2021-04-29 |
| Cationic Polymers App 20210113483 - DeRosa; Frank ; et al. | 2021-04-22 |
| Methods for purification of messenger RNA Grant 10,975,369 - DeRosa , et al. April 13, 2 | 2021-04-13 |
| Polyanionic delivery of nucleic acids Grant 10,961,184 - Heartlein , et al. March 30, 2 | 2021-03-30 |
| Lipid formulations for delivery of messenger RNA Grant 10,959,953 - Heartlein , et al. March 30, 2 | 2021-03-30 |
| Ice-based lipid nanoparticle formulation for delivery of mRNA Grant 10,940,207 - DeRosa , et al. March 9, 2 | 2021-03-09 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20210060177 - Guild; Braydon Charles ; et al. | 2021-03-04 |
| Stable Compositions Of Mrna-loaded Lipid Nanoparticles And Processes Of Making App 20210046192 - Karve; Shrirang ; et al. | 2021-02-18 |
| Lipid-derived Neutral Nanoparticles App 20210038519 - DeRosa; Frank ; et al. | 2021-02-11 |
| Biodegradable lipids for delivery of nucleic acids Grant 10,912,844 - DeRosa , et al. February 9, 2 | 2021-02-09 |
| Methods and compositions for delivering MRNA coded antibodies Grant 10,899,830 - Heartlein , et al. January 26, 2 | 2021-01-26 |
| Ionizable Cationic Lipids App 20210009503 - DeRosa; Frank ; et al. | 2021-01-14 |
| Ribonucleic Acids With 4'-thio-modified Nucleotides And Related Methods App 20210009629 - DeRosa; Frank ; et al. | 2021-01-14 |
| Lipid nanoparticle compositions and methods for mRNA delivery Grant 10,888,626 - Guild , et al. January 12, 2 | 2021-01-12 |
| Methods for purification of messenger RNA Grant 10,876,104 - Heartlein , et al. December 29, 2 | 2020-12-29 |
| Synergistic Enhancement of the Delivery of Nucleic Acids via Blended Formulations App 20200390797 - DeRosa; Frank ; et al. | 2020-12-17 |
| Messenger RNA therapy for treatment of articular disease Grant 10,864,267 - DeRosa , et al. December 15, 2 | 2020-12-15 |
| Messenger RNA therapy for the treatment of ornithine transcarbamylase deficiency Grant 10,835,583 - DeRosa , et al. November 17, 2 | 2020-11-17 |
| Ribonucleic acids with 4'-thio-modified nucleotides and related methods Grant 10,822,368 - DeRosa , et al. November 3, 2 | 2020-11-03 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20200338214 - Guild; Braydon Charles ; et al. | 2020-10-29 |
| Methods for purification of messenger RNA Grant 10,808,241 - Abysalh , et al. October 20, 2 | 2020-10-20 |
| Quantitative Assessment For Cap Efficiency Of Messenger Rna App 20200318156 - Heartlein; Michael ; et al. | 2020-10-08 |
| Lipid-derived neutral nanoparticles Grant 10,786,455 - DeRosa , et al. September 29, 2 | 2020-09-29 |
| Messenger RNA therapy for the treatment of Friedreich's ataxia Grant 10,780,183 - Heartlein , et al. Sept | 2020-09-22 |
| CNS delivery of MRNA and uses thereof Grant 10,780,052 - DeRosa , et al. Sept | 2020-09-22 |
| Ionizable cationic lipids Grant 10,766,852 - DeRosa , et al. Sep | 2020-09-08 |
| Poly(phosphoesters) For Delivery Of Nucleic Acids App 20200277446 - DeRosa; Frank ; et al. | 2020-09-03 |
| Cleavable Lipids App 20200237671 - Guild; Braydon Charles ; et al. | 2020-07-30 |
| Biodegradable Lipids For Delivery Of Nucleic Acids App 20200222558 - DeRosa; Frank ; et al. | 2020-07-16 |
| Composition And Methods For Treatment Of Primary Ciliary Dyskinesia App 20200215157 - Dias; Anusha ; et al. | 2020-07-09 |
| Cleavable lipids Grant 10,702,478 - Guild , et al. | 2020-07-07 |
| Multimeric Coding Nucleic Acid And Uses Thereof App 20200172923 - DeRosa; Frank ; et al. | 2020-06-04 |
| TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF NEBULIZED mRNA ENCODING CFTR App 20200157157 - KARVE; SHRIRANG ; et al. | 2020-05-21 |
| Methods And Compositions For Delivering Mrna Coded Antibodies App 20200157205 - Heartlein; Michael ; et al. | 2020-05-21 |
| Ice-based Lipid Nanoparticle Formulation For Delivery Of Mrna App 20200155691 - DeRosa; Frank ; et al. | 2020-05-21 |
| Synergistic enhancement of the delivery of nucleic acids via blended formulations Grant 10,646,504 - DeRosa , et al. | 2020-05-12 |
| Quantitative assessment for cap efficiency of messenger RNA Grant 10,626,439 - Heartlein , et al. | 2020-04-21 |
| Methods For Purification Of Messenger Rna App 20200095571 - Parella; Joseph ; et al. | 2020-03-26 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20200085973 - Guild; Braydon Charles ; et al. | 2020-03-19 |
| Process Of Preparing Mrna-loaded Lipid Nanoparticles App 20200085745 - Karve; Shrirang ; et al. | 2020-03-19 |
| Lipid Formulations For Delivery Of Messenger Rna App 20200078299 - Heartlein; Michael ; et al. | 2020-03-12 |
| Methods and compositions for delivering mRNA coded antibodies Grant 10,584,165 - Heartlein , et al. | 2020-03-10 |
| Liver specific delivery of messenger RNA Grant 10,576,166 - DeRosa , et al. | 2020-03-03 |
| Cftr Mrna Compositions And Related Methods And Uses App 20200046752 - Heartlein; Michael ; et al. | 2020-02-13 |
| Ice-based Lipid Nanoparticle Formulation For Delivery Of Mrna App 20200038515 - DeRosa; Frank ; et al. | 2020-02-06 |
| Dry Powder Formulations For Messenger Rna App 20200022921 - Karve; Shrirang ; et al. | 2020-01-23 |
| PolyAnionic Delivery of Nucleic Acids App 20200017440 - Heartlein; Michael ; et al. | 2020-01-16 |
| Messenger Rna Vaccines And Uses Thereof App 20200016274 - Karve; Shrirang ; et al. | 2020-01-16 |
| Mrna Therapeutic Compositions And Use To Treat Diseases And Disorders App 20190388563 - Heartlein; Michael | 2019-12-26 |
| Lipid nanoparticle compositions and methods for mRNA delivery Grant 10,507,249 - Guild , et al. Dec | 2019-12-17 |
| Cleavable lipids Grant 10,507,183 - Guild , et al. Dec | 2019-12-17 |
| Biodegradable lipids for delivery of nucleic acids Grant 10,493,166 - DeRosa , et al. De | 2019-12-03 |
| Lipid formulations for delivery of messenger RNA Grant 10,493,031 - Heartlein , et al. De | 2019-12-03 |
| Ice-based lipid nanoparticle formulation for delivery of mRNA Grant 10,471,153 - DeRosa , et al. Nov | 2019-11-12 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20190321489 - Guild; Braydon Charles ; et al. | 2019-10-24 |
| Cleavable Lipids App 20190314284 - Guild; Braydon Charles ; et al. | 2019-10-17 |
| Subcutaneous Delivery Of Messenger Rna App 20190298755 - Karve; Shrirang ; et al. | 2019-10-03 |
| Multimeric coding nucleic acid and uses thereof Grant 10,428,349 - DeRosa , et al. October 1, 2 | 2019-10-01 |
| CFTR MRNA compositions and related methods and uses Grant 10,420,791 - Heartlein , et al. Sept | 2019-09-24 |
| Lipid nanoparticle compositions and methods for mRNA delivery Grant 10,413,618 - Guild , et al. Sept | 2019-09-17 |
| Ribonucleic Acids With 4'-thio-modified Nucleotides And Related Methods App 20190263850 - DeRosa; Frank ; et al. | 2019-08-29 |
| Multimeric Coding Nucleic Acid And Uses Thereof App 20190249191 - DeRosa; Frank ; et al. | 2019-08-15 |
| Pulmonary Delivery Of Mrna To Non-lung Target Cells App 20190216730 - Heartlein; Michael ; et al. | 2019-07-18 |
| Synergistic Enhancement of the Delivery of Nucleic Acids via Blended Formulations App 20190216843 - DeRosa; Frank ; et al. | 2019-07-18 |
| Lipid nanoparticle compositions and methods for mRNA delivery Grant 10,350,303 - Guild , et al. July 16, 2 | 2019-07-16 |
| Mrna Therapy For Phenylketonuria App 20190211314 - DeRosa; Frank ; et al. | 2019-07-11 |
| Composition and Methods for Treatment of Ornithine Transcarbamylase Deficiency App 20190192688 - Askew; Kim ; et al. | 2019-06-27 |
| Lipid-derived Neutral Nanoparticles App 20190192435 - DeRosa; Frank ; et al. | 2019-06-27 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20190192689 - Guild; Braydon Charles ; et al. | 2019-06-27 |
| Liver Specific Delivery Of Messenger Rna App 20190192690 - Guild; Braydon Charles ; et al. | 2019-06-27 |
| Stereochemically Enriched Compositions For Delivery Of Nucleic Acids App 20190185435 - DeRosa; Frank ; et al. | 2019-06-20 |
| Ionizable Cationic Lipids App 20190185410 - DeRosa; Frank ; et al. | 2019-06-20 |
| Lipid Nanoparticle Compositions and Methods for mRNA Delivery App 20190175761 - Guild; Braydon Charles ; et al. | 2019-06-13 |
| Biodegradable lipids for delivery of nucleic acids Grant 10,293,057 - DeRosa , et al. | 2019-05-21 |
| Methods For Purification Of Messenger Rna App 20190144480 - DeRosa; Frank ; et al. | 2019-05-16 |
| Biodegradable lipids for delivery of nucleic acids Grant 10,286,082 - DeRosa , et al. | 2019-05-14 |
| Biodegradable lipids for delivery of nucleic acids Grant 10,286,083 - DeRosa , et al. | 2019-05-14 |
| Mrna Therapy For Pompe Disease App 20190134164 - DeRosa; Frank ; et al. | 2019-05-09 |
| Modification Of Rna-related Enzymes For Enhanced Production App 20190136283 - Strack-Logue; Bettina ; et al. | 2019-05-09 |
| Messenger Rna Based Viral Production App 20190127708 - Heartlein; Michael ; et al. | 2019-05-02 |
| Multimeric coding nucleic acid and uses thereof Grant 10,266,843 - DeRosa , et al. | 2019-04-23 |
| Ribonucleic acids with 4'-thio-modified nucleotides and related methods Grant 10,266,559 - DeRosa , et al. | 2019-04-23 |
| Nuclease Resistant Polynucleotides and Uses Thereof App 20190100753 - Heartlein; Michael ; et al. | 2019-04-04 |
| Pulmonary delivery of mRNA to non-lung target cells Grant 10,245,229 - Heartlein , et al. | 2019-04-02 |
| Lipid nanoparticle compositions and methods for MRNA delivery Grant 10,238,754 - Guild , et al. | 2019-03-26 |
| Methods And Compositions For Delivering Mrna Coded Antibodies App 20190071495 - Heartlein; Michael ; et al. | 2019-03-07 |
| MRNA therapy for phenylketonuria Grant 10,208,295 - DeRosa , et al. Feb | 2019-02-19 |
| MRNA therapy for pompe disease Grant 10,172,924 - DeRosa , et al. J | 2019-01-08 |
| Messenger Rna Therapy For The Treatment Of Friedreich's Ataxia App 20180369413 - Heartlein; Michael ; et al. | 2018-12-27 |
| Lipid Formulations For Delivery Of Messenger Rna App 20180369144 - Heartlein; Michael ; et al. | 2018-12-27 |
| Messenger Rna Therapy For Treatment Of Articular Disease App 20180360961 - DeRosa; Frank ; et al. | 2018-12-20 |
| Methods for purification of messenger RNA Grant 10,155,785 - DeRosa , et al. Dec | 2018-12-18 |
| COMPOSITIONS AND METHODS FOR mRNA DELIVERY App 20180353616 - Guild; Braydon Charles ; et al. | 2018-12-13 |
| Liver specific delivery of messenger RNA Grant 10,143,758 - Guild , et al. De | 2018-12-04 |
| Modification of RNA-related enzymes for enhanced production Grant 10,144,942 - Strack-Logue , et al. De | 2018-12-04 |
| Lipid-derived neutral nanoparticles Grant 10,137,087 - DeRosa , et al. November 27, 2 | 2018-11-27 |
| Lipid-derived neutral nanoparticles Grant 10,137,086 - DeRosa , et al. November 27, 2 | 2018-11-27 |
| Stereochemically enriched compositions for delivery of nucleic acids Grant 10,138,213 - DeRosa , et al. Nov | 2018-11-27 |
| TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF CODON-OPTIMIZED mRNA ENCODING CFTR App 20180333457 - Heartlein; Michael ; et al. | 2018-11-22 |
| Synergistic enhancement of the delivery of nucleic acids via blended formulations Grant 10,130,649 - Derosa , et al. November 20, 2 | 2018-11-20 |
| Quantitative Assessment For Cap Efficiency Of Messenger Rna App 20180291425 - Heartlein; Michael ; et al. | 2018-10-11 |
| Methods and compositions for delivering mRNA coded antibodies Grant 10,087,247 - Heartlein , et al. October 2, 2 | 2018-10-02 |
| Biodegradable Lipids for Delivery of Nucleic Acids App 20180272004 - DeRosa; Frank ; et al. | 2018-09-27 |
| Biodegradable Lipids for Delivery of Nucleic Acids App 20180272002 - DeRosa; Frank ; et al. | 2018-09-27 |
| Biodegradable Lipids for Delivery of Nucleic Acids App 20180272005 - DeRosa; Frank ; et al. | 2018-09-27 |
| Biodegradable Lipids for Delivery of Nucleic Acids App 20180272003 - DeRosa; Frank ; et al. | 2018-09-27 |
| Encapsulation Of Messenger Rna App 20180263918 - DeRosa; Frank ; et al. | 2018-09-20 |
| Novel Codon-Optimized CFTR MRNA App 20180256741 - Dias; Anusha ; et al. | 2018-09-13 |
| Large Scale Synthesis Of Messenger Rna App 20180258423 - Dias; Anusha ; et al. | 2018-09-13 |
| Methods For Purification Of Messenger Rna App 20180251754 - DeRosa; Frank ; et al. | 2018-09-06 |
| Methods For Purification of Messenger RNA App 20180251755 - Abysalh; Jonathan ; et al. | 2018-09-06 |
| Ionizable cationic lipids Grant 10,065,919 - DeRosa , et al. September 4, 2 | 2018-09-04 |
| mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES App 20180236047 - Guild; Braydon Charles ; et al. | 2018-08-23 |
| Methods For Purification Of Messenger Rna App 20180237766 - Heartlein; Michael ; et al. | 2018-08-23 |
| Lipid formulations for delivery of messenger RNA Grant 10,052,284 - Heartlein , et al. August 21, 2 | 2018-08-21 |
| Biodegradable lipids for delivery of nucleic acids Grant 10,022,455 - Derosa , et al. July 17, 2 | 2018-07-17 |
| Lipid-derived Neutral Nanoparticles App 20180169016 - DeRosa; Frank ; et al. | 2018-06-21 |
| Cleavable Lipids App 20180169020 - Guild; Braydon Charles ; et al. | 2018-06-21 |
| Lipid-derived Neutral Nanoparticles App 20180169015 - DeRosa; Frank ; et al. | 2018-06-21 |
| Process of Preparing mRNA-Loaded Lipid Nanoparticles App 20180153822 - Karve; Shrirang ; et al. | 2018-06-07 |
| Quantitative assessment for cap efficiency of messenger RNA Grant 9,970,047 - Heartlein , et al. May 15, 2 | 2018-05-15 |
| Methods For Purification Of Messenger Rna App 20180127449 - DeRosa; Frank ; et al. | 2018-05-10 |
| Ice-based Lipid Nanoparticle Formulation For Delivery Of Mrna App 20180125989 - DeRosa; Frank ; et al. | 2018-05-10 |
| mRNA for use in treatment of human genetic diseases Grant 9,956,271 - Guild , et al. May 1, 2 | 2018-05-01 |
| Methods for purification of messenger RNA Grant 9,957,499 - Heartlein , et al. May 1, 2 | 2018-05-01 |
| Messenger RNA therapy for treatment of articular disease Grant 9,943,595 - DeRosa , et al. April 17, 2 | 2018-04-17 |
| Mitochondrial targeting and therapeutic use thereof Grant 9,932,377 - Keefe , et al. April 3, 2 | 2018-04-03 |
| Cns Delivery Of Mrna And Uses Thereof App 20180028445 - DeRosa; Frank ; et al. | 2018-02-01 |
| Lipid-derived neutral nanoparticles Grant 9,877,919 - DeRosa , et al. January 30, 2 | 2018-01-30 |
| Cftr Mrna Compositions And Related Methods And Uses App 20180015116 - Heartlein; Michael ; et al. | 2018-01-18 |
| Cleavable Lipids App 20180008543 - Guild; Braydon Charles ; et al. | 2018-01-11 |
| Cells For Producing Recombinant Iduronate-2-sulfatase App 20180010108 - Boldog; Ferenc ; et al. | 2018-01-11 |
| Messenger RNA Therapy for the Treatment of Ornithine Transcarbamylase Deficiency App 20180008680 - DeRosa; Frank ; et al. | 2018-01-11 |
| Methods for purification of messenger RNA Grant 9,850,269 - DeRosa , et al. December 26, 2 | 2017-12-26 |
| Encapsulation Of Messenger Rna App 20170348244 - DeRosa; Frank ; et al. | 2017-12-07 |
| Multimeric Coding Nucleic Acid And Uses Thereof App 20170314041 - DeRosa; Frank ; et al. | 2017-11-02 |
| Lipid Formulations For Delivery Of Messenger Rna App 20170281542 - Heartlein; Michael ; et al. | 2017-10-05 |
| Biodegradable Lipids For Delivery Of Nucleic Acids App 20170246319 - DEROSA; Frank ; et al. | 2017-08-31 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20170239371 - Guild; Braydon Charles ; et al. | 2017-08-24 |
| Ionizable Cationic Lipids App 20170240501 - DeRosa; Frank ; et al. | 2017-08-24 |
| Cleavable lipids Grant 9,717,690 - Guild , et al. August 1, 2 | 2017-08-01 |
| Cells for producing recombinant iduronate-2-sulfatase Grant 9,719,074 - Boldog , et al. August 1, 2 | 2017-08-01 |
| CFTR mRNA compositions and related methods and uses Grant 9,713,626 - Heartlein , et al. July 25, 2 | 2017-07-25 |
| Modification Of Rna-related Enzymes For Enhanced Production App 20170159093 - Strack-Logue; Bettina ; et al. | 2017-06-08 |
| Encapsulation of messenger RNA Grant 9,668,980 - DeRosa , et al. June 6, 2 | 2017-06-06 |
| Mrna Therapy For The Treatment Of Ocular Diseases App 20170143848 - CALIAS; Pericles ; et al. | 2017-05-25 |
| Lipid formulations for delivery of messenger RNA Grant 9,629,804 - Heartlein , et al. April 25, 2 | 2017-04-25 |
| Pulmonary delivery of mRNA Grant 9,597,413 - Guild , et al. March 21, 2 | 2017-03-21 |
| Mrna Therapy For Phenylketonuria App 20170073648 - DeRosa; Frank ; et al. | 2017-03-16 |
| Ionizable cationic lipids Grant 9,546,128 - DeRosa , et al. January 17, 2 | 2017-01-17 |
| MRNA therapy for phenylketonuria Grant 9,522,176 - DeRosa , et al. December 20, 2 | 2016-12-20 |
| Mrna Therapy For Pompe Disease App 20160324940 - DeRosa; Frank ; et al. | 2016-11-10 |
| Liver Specific Delivery Of Messenger Rna App 20160287725 - DeRosa; Frank ; et al. | 2016-10-06 |
| Mitochondrial Targeting And Therapeutic Use Thereof App 20160237129 - Keefe; Dennis ; et al. | 2016-08-18 |
| Mrna Therapeutic Compositions And Use To Treat Diseases And Disorders App 20160184458 - Heartlein; Michael | 2016-06-30 |
| Messenger RNA Therapy for Treatment of Articular Disease App 20160158354 - DeRosa; Frank ; et al. | 2016-06-09 |
| Synergistic Enhancement Of The Delivery Of Nucleic Acids Via Blended Formulations App 20160151409 - Derosa; Frank ; et al. | 2016-06-02 |
| Messenger Rna Based Viral Production App 20160122727 - Heartlein; Michael ; et al. | 2016-05-05 |
| Cftr Mrna Compositions And Related Methods And Uses App 20160106772 - Heartlein; Michael ; et al. | 2016-04-21 |
| mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES App 20160101160 - Guild; Braydon Charles ; et al. | 2016-04-14 |
| MRNA therapy for Fabry disease Grant 9,308,281 - Guild , et al. April 12, 2 | 2016-04-12 |
| Cells For Producing Recombinant Iduronate-2-sulfatase App 20160053238 - Boldog; Ferenc ; et al. | 2016-02-25 |
| Mitochondrial targeting and therapeutic use thereof Grant 9,260,495 - Keefe , et al. February 16, 2 | 2016-02-16 |
| Methods For Purification Of Messenger Rna App 20160040154 - Heartlein; Michael ; et al. | 2016-02-11 |
| Encapsulation Of Messenger Rna App 20160038432 - DeRosa; Frank ; et al. | 2016-02-11 |
| RIBONUCLEIC ACIDs WITH 4'-THIO-MODIFIED NUCLEOTIDES AND RELATED METHODS App 20160031928 - Derosa; Frank ; et al. | 2016-02-04 |
| Methods And Compositions For Delivering Mrna Coded Antibodies App 20160031981 - Heartlein; Michael ; et al. | 2016-02-04 |
| Quantitative Assessment For Cap Efficiency Of Messenger Rna App 20160032356 - Heartlein; Michael ; et al. | 2016-02-04 |
| Quantitative Assessment For Cap Efficiency Of Messenger Rna App 20160002705 - Heartlein; Michael ; et al. | 2016-01-07 |
| Stereochemically Enriched Compositions For Delivery Of Nucleic Acids App 20150376144 - DeRosa; Frank ; et al. | 2015-12-31 |
| Methods For Purification Of Messenger Rna App 20150376220 - DeRosa; Frank ; et al. | 2015-12-31 |
| COMPOSITIONS AND METHODS FOR mRNA DELIVERY App 20150366997 - Guild; Braydon Charles ; et al. | 2015-12-24 |
| CFTR mRNA compositions and related methods and uses Grant 9,181,321 - Heartlein , et al. November 10, 2 | 2015-11-10 |
| Cells for producing recombinant iduronate-2-sulfatase Grant 9,150,841 - Boldog , et al. October 6, 2 | 2015-10-06 |
| Nuclease Resistant Polynucleotides And Uses Thereof App 20150267192 - Heartlein; Michael ; et al. | 2015-09-24 |
| mRNA for use in treatment of human genetic diseases Grant 9,061,021 - Guild , et al. June 23, 2 | 2015-06-23 |
| Ionizable Cationic Lipids App 20150166462 - DeRosa; Frank ; et al. | 2015-06-18 |
| Pulmonary Delivery Of Mrna To Non-lung Target Cells App 20150157565 - Heartlein; Michael ; et al. | 2015-06-11 |
| Lipid Formulations For Delivery Of Messenger Rna App 20150140070 - Heartlein; Michael ; et al. | 2015-05-21 |
| Mrna Therapy For Phenylketonuria App 20150110858 - DeRosa; Frank ; et al. | 2015-04-23 |
| Mrna Therapy For Argininosuccinate Synthetase Deficiency App 20150110859 - Heartlein; Michael ; et al. | 2015-04-23 |
| Cns Delivery Of Mrna And Uses Thereof App 20150110857 - DeRosa; Frank ; et al. | 2015-04-23 |
| Lipid-derived Neutral Nanoparticles App 20150086613 - DeRosa; Frank ; et al. | 2015-03-26 |
| Cftr Mrna Compositions And Related Methods And Uses App 20150038556 - Heartlein; Michael ; et al. | 2015-02-05 |
| Methods for treating lysosomal acid lipase deficiency Grant 8,945,542 - Heartlein , et al. February 3, 2 | 2015-02-03 |
| mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES App 20150004217 - Guild; Braydon Charles ; et al. | 2015-01-01 |
| mRNA for use in treatment of human genetic diseases Grant 8,853,377 - Guild , et al. October 7, 2 | 2014-10-07 |
| Mrna Therapy For Urea Cycle Disorders App 20140294940 - Guild; Braydon Charles ; et al. | 2014-10-02 |
| Pulmonary Delivery Of Mrna App 20140294939 - Guild; Braydon Charles ; et al. | 2014-10-02 |
| Mrna Therapy For Fabry Disease App 20140294938 - Guild; Braydon Charles ; et al. | 2014-10-02 |
| Cleavable Lipids App 20140288160 - Guild; Braydon Charles ; et al. | 2014-09-25 |
| Lipid Nanoparticle Compositions And Methods For Mrna Delivery App 20140206753 - Guild; Braydon Charles ; et al. | 2014-07-24 |
| Mitochondrial Targeting And Therapeutic Use Thereof App 20140135275 - Keefe; Dennis ; et al. | 2014-05-15 |
| Methods For Treating Lysosomal Acid Lipase Deficiency App 20140044697 - Heartlein; Michael ; et al. | 2014-02-13 |
| Cells For Producing Recombinant Iduronate-2-sulfatase App 20140004593 - Boldog; Ferenc ; et al. | 2014-01-02 |
| Methods for Treating Lysosomal Acid Lipase Deficiency App 20130330317 - Grabowski; Gregory ; et al. | 2013-12-12 |
| Liver Specific Delivery Of Messenger Rna App 20130195967 - Guild; Braydon Charles ; et al. | 2013-08-01 |
| mRNA FOR USE IN TREATMENT OF HUMAN GENETIC DISEASES App 20120142756 - Guild; Braydon Charles ; et al. | 2012-06-07 |
| Delivery Of Mrna For The Augmentation Of Proteins And Enzymes In Human Genetic Diseases App 20110244026 - Guild; Braydon Charles ; et al. | 2011-10-06 |
Company Registrations
| SEC | 0001744680 | Heartlein Michael |
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