| Patent | Date |
|---|
Methods for Improving Cell Viability In A Production BioReactor
App 20220308042 - Wang; Jonathan ; et al. | 2022-09-29 |
Dose Escalation Enzyme Replacement Therapy For Treating Acid Sphingomyelinase Deficiency
App 20220305091 - Schuchman; Edward H. ; et al. | 2022-09-29 |
Compositions And Methods For Treating And Preventing Macular Degeneration
App 20220288232 - SCARIA; Abraham | 2022-09-15 |
Tangential viral filtration
Grant 11,440,010 - Vetter , et al. September 13, 2 | 2022-09-13 |
Perfusion bioreactor with filtration systems
Grant 11,434,464 - Lu , et al. September 6, 2 | 2022-09-06 |
Two-dimensional Lc-ms/ms Systems
App 20220252559 - Chuang; Wei-Lien ; et al. | 2022-08-11 |
Tropomyosin-related kinase (TRK) inhibitors
Grant 11,406,644 - Kane, Jr. , et al. August 9, 2 | 2022-08-09 |
Methods For Enhanced Removal Of Impurities During Protein A Chromatography
App 20220242902 - BEIGIE; Carl A. | 2022-08-04 |
Oligosaccharide-protein Conjugates
App 20220242899 - AVILA; Luis Z. ; et al. | 2022-08-04 |
Methods for improving cell viability in a production bioreactor
Grant 11,391,725 - Wang , et al. July 19, 2 | 2022-07-19 |
Humanized Anti-complement Factor Bb Antibodies And Uses Thereof
App 20220213179 - Parry; Graham ; et al. | 2022-07-07 |
Deuterated Colony Stimulating Factor-1 Receptor (csf-1r) Inhibitors
App 20220204504 - Kane, JR.; John L. ; et al. | 2022-06-30 |
Oligosaccharides Comprising An Aminooxy Group And Conjugates Thereof
App 20220204963 - ZHU; Yunxiang ; et al. | 2022-06-30 |
Sterile chromatography resin and use thereof in manufacturing processes
Grant 11,369,703 - Patil , et al. June 28, 2 | 2022-06-28 |
Gene therapy for lysosomal storage diseases
Grant 11,369,693 - Dodge , et al. June 28, 2 | 2022-06-28 |
Methods for Treating Osteogenesis Imperfecta
App 20220195025 - Lee; Brendan ; et al. | 2022-06-23 |
Assays For Detecting The Presence Or Amount Of An Anti-drug Antibody
App 20220187327 - Grabert; Ryan ; et al. | 2022-06-16 |
Anti-alpha Beta Tcr Binding Polypeptides With Reduced Fragmentation
App 20220153840 - QIU; Huawei | 2022-05-19 |
Anti-alphabetatcr Antibody
App 20220153841 - Snell; Daniel ; et al. | 2022-05-19 |
Methods Of Culturing A Mammalian Cell
App 20220145348 - Hwang; Christopher ; et al. | 2022-05-12 |
Modified-IgG antibodies that bind transforming growth factor-.beta.1 with high affinity, avidity and specificity
Grant 11,325,970 - Qiu , et al. May 10, 2 | 2022-05-10 |
scFv-Fc dimers that bind transforming growth factor-.beta.1 with high affinity, avidity and specificity
Grant 11,325,971 - Qiu , et al. May 10, 2 | 2022-05-10 |
Site-specific Glycoengineering Of Targeting Moieties
App 20220119547 - AVILA; Luis ; et al. | 2022-04-21 |
Methods of culturing a mammalian cell
Grant 11,306,341 - Hwang , et al. April 19, 2 | 2022-04-19 |
Pharmaceutical Formulations Of Tropomyosin Related Kinase (trk) Inhibitors
App 20220110861 - Lieberman; Harvey ; et al. | 2022-04-14 |
Human Pah Expression Cassette For Treatment Of Pku By Liver-directed Gene Replacement Therapy
App 20220112520 - KYOSTIO-MOORE; Sirkka R.M. | 2022-04-14 |
Treatment Of Ciliopathies Using Inhibitors Of Glucosylceramide Synthase (gcs)
App 20220110922 - IBRAGHIMOV-BESKROVNAYA; Oxana ; et al. | 2022-04-14 |
Use of iNOS inhibitors to increase viral yield in culture
Grant 11,299,715 - Pechan , et al. April 12, 2 | 2022-04-12 |
Multivariate Spectral Analysis and Monitoring for Biomanufacturing
App 20220101953 - Wasalathanthri; Dhanuka Pulasthi ; et al. | 2022-03-31 |
Methods For Enhancing Immunosuppressive Therapy By Multiple Administration Of Alpha Beta Tcr-binding Polypeptide
App 20220098299 - Blank; Gregor ; et al. | 2022-03-31 |
Tangential Viral Filtration
App 20220088602 - Vetter; Tarl ; et al. | 2022-03-24 |
Glycoengineered Antibody Drug Conjugates
App 20220088214 - Avila; Luis Z. ; et al. | 2022-03-24 |
Site-specific Antibody-drug Conjugation Through Glycoengineering
App 20220089763 - Pan; Clark ; et al. | 2022-03-24 |
Oligosaccharide-protein conjugates
Grant 11,279,725 - Avila , et al. March 22, 2 | 2022-03-22 |
SERPINC1 iRNA Compositions and Methods of Use Thereof
App 20220079971 - Akinc; Akin | 2022-03-17 |
Integrated Continuous Isolation of Fluid Streams From Sterile Process Vessels
App 20220081669 - Snow; Robert | 2022-03-17 |
Colony stimulating factor-1 receptor (CSF-1R) inhibitors
Grant 11,274,108 - Kane, Jr. , et al. March 15, 2 | 2022-03-15 |
Perfusion Bioreactor With Filtration Systems
App 20220073861 - Lu; Jiuyi ; et al. | 2022-03-10 |
Glucosylceramide Synthase Inhibitors
App 20220073508 - BOURQUE; Elyse ; et al. | 2022-03-10 |
Crosslinked polydiallymine copolymers for the treatment of type 2 diabetes
Grant 11,267,924 - Dhal , et al. March 8, 2 | 2022-03-08 |
Recombinant Glycoproteins and Uses Thereof
App 20220064617 - Lee; Karen ; et al. | 2022-03-03 |
Fusion Proteins Comprising Pdgf And Vegf Binding Portions And Methods Of Using Thereof
App 20220064262 - PECHAN; Peter ; et al. | 2022-03-03 |
Methods for producing preparations of recombinant AAV virions substantially free of empty capsids
Grant 11,261,463 - Qu , et al. March 1, 2 | 2022-03-01 |
Gene Therapy For Retinitis Pigmentosa
App 20220054657 - O'RIORDAN; Catherine ; et al. | 2022-02-24 |
Fgfr3 Antibodies And Methods Of Use
App 20220056142 - SABBAGH; Yves ; et al. | 2022-02-24 |
Slow intraventricular delivery
Grant 11,253,485 - Dodge , et al. February 22, 2 | 2022-02-22 |
Humanized anti-complement factor Bb antibodies
Grant 11,242,382 - Parry , et al. February 8, 2 | 2022-02-08 |
Chemical Process for the Synthesis of 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)qu- inazoline
App 20220033377 - Blixt; Jorgen ; et al. | 2022-02-03 |
Methods for enhanced removal of impurities during protein A chromatography
Grant 11,236,126 - Beigie February 1, 2 | 2022-02-01 |
Pharmaceutical Compositions Comprising Venglustat
App 20220023272 - JEANJEAN; Audrey ; et al. | 2022-01-27 |
Methods For Treating Symptoms And Disorders Associated With Lysosomal Storage Diseases
App 20220023273 - CRAWFORD; Nigel Patrick Somerville ; et al. | 2022-01-27 |
Methods for treating osteogenesis imperfecta
Grant 11,230,595 - Lee , et al. January 25, 2 | 2022-01-25 |
Methods For Treating Symptoms And Disorders Associated With Lysosomal Storage Diseases
App 20220016092 - CRAWFORD; Nigel Patrick Somerville ; et al. | 2022-01-20 |
Aav Virions With Decreased Immunoreactivity And Uses Therefor
App 20220016264 - ARBETMAN; Alejandra E. ; et al. | 2022-01-20 |
Methods And Compositions For Treating A Serpinc1-associated Disorder
App 20220017902 - Akinc; Akin ; et al. | 2022-01-20 |
Anti-Human CD52 Immunoglobulins
App 20220010024 - Roberts; Bruce L. ; et al. | 2022-01-13 |
Methods For The Quantitation Of Polypeptides
App 20220003780 - MORGAN; Christopher ; et al. | 2022-01-06 |
Assays for detecting the presence or amount of an anti-drug antibody
Grant 11,215,623 - Grabert , et al. January 4, 2 | 2022-01-04 |
Recombinant glycoproteins and uses thereof
Grant 11,208,644 - Lee , et al. December 28, 2 | 2021-12-28 |
Methods And Compositions For Treating Hemophilia
App 20210393669 - Mei; Baisong ; et al. | 2021-12-23 |
Inhibitors Of Glucosylceramide Synthase
App 20210393590 - LIU; Hanlan ; et al. | 2021-12-23 |
Elution of biomolecules from multi-modal resins using MES and MOPS as mobile phase modifiers
Grant 11,203,747 - Godawat , et al. December 21, 2 | 2021-12-21 |
Biomarker Of Polycystic Kidney Disease And Uses Thereof
App 20210379031 - Bukanov; Nikolai ; et al. | 2021-12-09 |
Inhibitors Of T-cell Activation
App 20210380686 - Zhu; Yunxiang ; et al. | 2021-12-09 |
Rabbit Antibodies To Human Immunoglobulins G
App 20210380719 - CHU; Ruiyin | 2021-12-09 |
Anti-.alpha..beta.TCR antibody
Grant 11,186,638 - Snell , et al. November 30, 2 | 2021-11-30 |
Methods For Preventing Retropulsion Of Concretions And Fragments During Lithotripsy
App 20210353301 - Vogel; Jean-Marie ; et al. | 2021-11-18 |
Generation Of Improved Human Pah For Treatment Of Severe Pku By Liver-directed Gene Replacement Therapy
App 20210348135 - KYOSTIO-MOORE; Sirkka ; et al. | 2021-11-11 |
Glycoengineered antibody drug conjugates
Grant 11,160,874 - Avila , et al. November 2, 2 | 2021-11-02 |
Humanized Anti-complement Factor Bb Antibodies And Uses Thereof
App 20210332115 - Parry; Graham ; et al. | 2021-10-28 |
Methods For Treating Gaucher Disease
App 20210330633 - LI; Jing ; et al. | 2021-10-28 |
Perfusion Culturing Methods and Uses Thereof
App 20210324328 - Villiger-Oberbek; Agata ; et al. | 2021-10-21 |
Methods for enhancing immunosuppressive therapy by multiple administration of .alpha..beta.TCR-binding polypeptide
Grant 11,142,575 - Blank , et al. October 12, 2 | 2021-10-12 |
VARIANT RNAi AGAINST ALPHA-SYNUCLEIN
App 20210309999 - ELMER; Bradford ; et al. | 2021-10-07 |
Site-specific antibody-drug conjugation through glycoengineering
Grant 11,130,816 - Pan , et al. September 28, 2 | 2021-09-28 |
Modified Binding Polypeptides For Optimized Drug Conjugation
App 20210292391 - Zhou; Qun ; et al. | 2021-09-23 |
Biomarker of polycystic kidney disease and uses thereof
Grant 11,116,755 - Moreno , et al. September 14, 2 | 2021-09-14 |
Quinazoline Derivatives as VEGF Inhibitors
App 20210276972 - Thomas; Andrew Peter ; et al. | 2021-09-09 |
Pharmaceutical formulations of tropomyosin related kinase (TRK) inhibitors
Grant 11,110,055 - Lieberman , et al. September 7, 2 | 2021-09-07 |
Methods and Systems for Processing a Cell Culture
App 20210269477 - Konstantinov; Konstantin ; et al. | 2021-09-02 |
Sterile Chromatography Resin And Use Thereof In Manufacturing Processes
App 20210268477 - Godawat; Rahul ; et al. | 2021-09-02 |
Multiple oligonucleotide moieties on peptide carrier
Grant 11,103,587 - Weeden , et al. August 31, 2 | 2021-08-31 |
Gene therapy for retinitis pigmentosa
Grant 11,103,598 - O'Riordan , et al. August 31, 2 | 2021-08-31 |
Modified Adeno-associated Viral Capsid Proteins For Ocular Gene Therapy And Methods Of Use Thereof
App 20210261625 - Frederick; Amy ; et al. | 2021-08-26 |
Glucosylceramide Synthase Inhibitors
App 20210261557 - BOURQUE; Elyse ; et al. | 2021-08-26 |
UDP glycosyltransferase inhibitors and methods of use
Grant 11,098,056 - Lim , et al. August 24, 2 | 2021-08-24 |
Methods For Treating Neurological Symptoms Associated With Lysosomal Storage Diseases
App 20210251982 - CRAWFORD; Nigel Patrick Somerville ; et al. | 2021-08-19 |
SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
App 20210254063 - Akinc; Akin ; et al. | 2021-08-19 |
Methods and compositions for treating a Serpinc1-associated disorder
Grant 11,091,759 - Akinc , et al. August 17, 2 | 2021-08-17 |
Therapeutic Tyrosine Kinase Inhibitors for Relapsing Multiple Sclerosis (RMS)
App 20210244720 - Cho; Meehyung ; et al. | 2021-08-12 |
Compositions And Methods For Treating Pompe Disease
App 20210244803 - AN HAACK; Kristina ; et al. | 2021-08-12 |
Fusion proteins comprising PDGF and VEGF binding portions and methods of using thereof
Grant 11,084,864 - Pechan , et al. August 10, 2 | 2021-08-10 |
AAV virions with decreased immunoreactivity and uses therefor
Grant 11,083,800 - Arbetman , et al. August 10, 2 | 2021-08-10 |
Intraventricular Enzyme Delivery For Lysosomal Storage Diseases
App 20210228692 - DODGE; James ; et al. | 2021-07-29 |
Methods for the quantitation of polypeptides
Grant 11,067,584 - Morgan , et al. July 20, 2 | 2021-07-20 |
Perfusion culturing methods and uses thereof
Grant 11,060,058 - Villiger-Oberbek , et al. July 13, 2 | 2021-07-13 |
Aav Vectors For Retinal And Cns Gene Therapy
App 20210189430 - SCARIA; Abraham ; et al. | 2021-06-24 |
Methods Of Processing A Fluid Including A Recombinant Therapeutic Protein And Use Thereof
App 20210171572 - Vetter; Tarl ; et al. | 2021-06-10 |
Synthesis Of Udp-glucose: N-acylsphingosine Glucosyltransferase Inhibitors
App 20210171507 - HIRTH; Bradford H. ; et al. | 2021-06-10 |
Tropomyosin-Related Kinase (TRK) Inhibitors
App 20210169894 - Kane, JR.; John L. ; et al. | 2021-06-10 |
Inhibitors of T-cell activation
Grant 11,028,170 - Zhu , et al. June 8, 2 | 2021-06-08 |
Use Of Cxcr4 Antagonists
App 20210161859 - DALE; David C. ; et al. | 2021-06-03 |
Bone-Targeting Antibodies
App 20210163584 - Qiu; Huawei ; et al. | 2021-06-03 |
Marker For Acid Sphingomyelinase Disorders And Uses Thereof
App 20210162021 - Chuang; Wei-Lien ; et al. | 2021-06-03 |
Pharmaceutical Compositions For Treating Acid Sphingomyelinase Deficiency
App 20210145941 - Yang; Mark ; et al. | 2021-05-20 |
Fc Containing Polypeptides With Altered Glycosylation And Reduced Effector Function
App 20210147524 - PAN; Clark ; et al. | 2021-05-20 |
Glucosylceramide synthase inhibitors
Grant 11,008,316 - Bourque , et al. May 18, 2 | 2021-05-18 |
Methods For Purification Of Recombinant Aav Vectors
App 20210139860 - SHELDON; Paulene McLean Quigley ; et al. | 2021-05-13 |
Site-specific glycoengineering of targeting moieties
Grant 10,995,148 - Avila , et al. May 4, 2 | 2021-05-04 |
Polynucleotide Agents Targeting Serpinc1 (at3) And Methods Of Use Thereof
App 20210123049 - Hinkle; Gregory | 2021-04-29 |
Compositions And Methods For Treating Spinal Muscular Atrophy
App 20210121523 - PASSINI; Marco A. ; et al. | 2021-04-29 |
In-line Product Monitoring In Integrated Continuous Bio-manufacturing
App 20210115385 - Snow; Robert ; et al. | 2021-04-22 |
AAV vectors for retinal and CNS gene therapy
Grant 10,982,228 - Scaria , et al. April 20, 2 | 2021-04-20 |
Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins and its application thereof
Grant 10,973,887 - Zhu April 13, 2 | 2021-04-13 |
Methods For Absolute Quantification Of Low-abundance Polypeptides Using Mass Spectrometry
App 20210102952 - STAPELS; Martha ; et al. | 2021-04-08 |
Methods of processing a fluid including a recombinant therapeutic protein and use thereof
Grant 10,968,252 - Vetter , et al. April 6, 2 | 2021-04-06 |
Product Quality Attribute Measurement
App 20210087514 - Hincapie; Marina ; et al. | 2021-03-25 |
Methods for treating cancer
Grant 10,953,003 - Ragan , et al. March 23, 2 | 2021-03-23 |
Method of preparing glucosylceramide synthase inhibitors
Grant 10,954,230 - Siegel , et al. March 23, 2 | 2021-03-23 |
Dose Escalation Enzyme Replacement Therapy For Treating Acid Sphingomyelinase Deficiency
App 20210077593 - Schuchman; Edward H. ; et al. | 2021-03-18 |
Antibodies to TGF-Beta
App 20210061897 - Ledbetter; Steven R. ; et al. | 2021-03-04 |
Anti-complement factor BB antibodies and uses thereof
Grant 10,934,347 - Panicker , et al. March 2, 2 | 2021-03-02 |
VARIANT RNAi
App 20210047641 - STANEK; Lisa M. ; et al. | 2021-02-18 |
Affinity-based analytical purification of biotherapeutics for bioprocess monitoring
Grant 10,920,182 - Warikoo , et al. February 16, 2 | 2021-02-16 |
Gene therapy for amyotrophic lateral sclerosis and other spinal cord disorders
Grant 10,920,245 - O'Riordan , et al. February 16, 2 | 2021-02-16 |
Sterile chromatography resin and use thereof in manufacturing processes
Grant 10,919,021 - Godawat , et al. February 16, 2 | 2021-02-16 |
Compositions And Methods For Treating And Preventing Macular Degeneration
App 20210040484 - WADSWORTH; Samuel ; et al. | 2021-02-11 |
Methods For Detecting Aav
App 20210041451 - JIN; Xiaoying ; et al. | 2021-02-11 |
Gene therapy for neurometabolic disorders
Grant 10,913,956 - Passini , et al. February 9, 2 | 2021-02-09 |
Inhibiting Or Downregulating Glycogen Synthase By Creating Premature Stop Codons Using Antisense Oligonucleotides
App 20210030893 - NELSON; Carol A. ; et al. | 2021-02-04 |
Oligosaccharides comprising an aminooxy group and conjugates thereof
Grant 10,907,142 - Zhu , et al. February 2, 2 | 2021-02-02 |
Methods of Treating Antibody-Mediated Disorders with FcRn Antagonists
App 20210024620 - Mackness; Brian ; et al. | 2021-01-28 |
Methods for absolute quantification of low-abundance polypeptides using mass spectrometry
Grant 10,900,972 - Stapels , et al. January 26, 2 | 2021-01-26 |
Gene Therapy For Spinal Cord Disorders
App 20210008227 - DODGE; James ; et al. | 2021-01-14 |
Biomarkers Of Methotrexate-induced Immune Tolerance
App 20210008074 - JOSEPH; Alexandra ; et al. | 2021-01-14 |
Methods for treating Gaucher disease
Grant 10,888,544 - Li , et al. January 12, 2 | 2021-01-12 |
Marker for acid sphingomyelinase disorders and uses thereof
Grant 10,888,607 - Chuang , et al. January 12, 2 | 2021-01-12 |
Amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase
Grant 10,888,547 - Peterschmitt January 12, 2 | 2021-01-12 |
Integrated Continuous Isolation of Fluid Streams From Sterile Process Vessels
App 20210002601 - Snow; Robert | 2021-01-07 |
Biomarkers of polycystic kidney disease and uses thereof
Grant 10,871,495 - Beskrovnaya , et al. December 22, 2 | 2020-12-22 |
Gene Therapy For Neurodegenerative Disorders
App 20200384076 - PASSINI; Marco A. ; et al. | 2020-12-10 |
Methods For Quantifying Drug Concentration In A Prodrug Composition
App 20200386768 - Alving; Kim ; et al. | 2020-12-10 |
Seed Train Processes And Uses Thereof
App 20200377850 - Bruninghaus; Michael ; et al. | 2020-12-03 |
Sterile Chromatography And Manufacturing Processes
App 20200369718 - Godawat; Rahul ; et al. | 2020-11-26 |
Bone-targeting antibodies
Grant 10,844,115 - Qiu , et al. November 24, 2 | 2020-11-24 |
Induction Of Immune Tolerance By Using Methotrexate
App 20200360385 - JOSEPH; Alexandra ; et al. | 2020-11-19 |
Fc containing polypeptides with altered glycosylation and reduced effector function
Grant 10,836,813 - Pan , et al. November 17, 2 | 2020-11-17 |
Fusion proteins and methods for inhibiting IL-17 pathways
Grant 10,822,391 - Scaria , et al. November 3, 2 | 2020-11-03 |
Compositions and methods for treating spinal muscular atrophy
Grant 10,821,154 - Passini , et al. November 3, 2 | 2020-11-03 |
Adeno-associated viral vectors for treating myocilin (MYOC) glaucoma
Grant 10,821,193 - Pechan , et al. November 3, 2 | 2020-11-03 |
Production of oversized adeno-associated vectors
Grant 10,815,497 - Kyostio-Moore , et al. October 27, 2 | 2020-10-27 |
Integrated Continuous Manufacturing of Therapeutic Protein Drug Substances
App 20200317726 - Konstantinov; Konstantin ; et al. | 2020-10-08 |
Continuous Production Of Recombinant Proteins
App 20200317728 - Coolbaugh; Michael ; et al. | 2020-10-08 |
Targeting of glycoprotein therapeutics
Grant 10,792,342 - Stefano October 6, 2 | 2020-10-06 |
Gene Therapy For Neurometabolic Disorders
App 20200306387 - PASSINI; Marco A. ; et al. | 2020-10-01 |
Methods of Controlling the Formation of Disulfide Bonds in Protein Solutions
App 20200299402 - Brower; Kevin P. ; et al. | 2020-09-24 |
Treatment of Multiple Sclerosis with Anti-CD52 Antibodies
App 20200299399 - MARGOLIN; David H. | 2020-09-24 |
Early Post-transfection Isolation Of Cells (epic) For Biologics Production
App 20200299743 - Cairns; Victor R. ; et al. | 2020-09-24 |
Antibodies to TGF-.beta.
Grant 10,781,252 - Ledbetter , et al. Sept | 2020-09-22 |
Tangential Viral Filtration
App 20200290044 - Vetter; Tarl ; et al. | 2020-09-17 |
Variant RNAi
Grant 10,760,079 - Stanek , et al. Sep | 2020-09-01 |
Adeno-associated Viral Vectors For Treating Mucolipidosis Type Ii
App 20200261598A1 - | 2020-08-20 |
Quinazoline Derivatives as VEGF Inhibitors
App 20200262811 - Thomas; Andrew Peter ; et al. | 2020-08-20 |
Gene therapy for spinal cord disorders
Grant 10,744,210 - Dodge , et al. A | 2020-08-18 |
Antibodies With Enhanced Antibody-dependent Cellular Cytotoxicity Activity, Methods Of Their Production And Use
App 20200255518A1 - | 2020-08-13 |
Methods Of Perfusion Culturing Using A Shake Flask And Microcarriers
App 20200255798 - Yang; Jianguo ; et al. | 2020-08-13 |
Engineered anti-TGF-.beta. antibodies and antigen-binding fragments
Grant 10,730,936 - Wei , et al. | 2020-08-04 |
Recombinant Aav Vectors Expressing Osteoprotective Genes, Including Has2 And Lubricin, Useful In The Treatment Of Osteoarthritis And Related Joint Conditions In Mammals
App 20200231940A1 - | 2020-07-23 |
Analytical Ultracentrifugation For Characterization Of Recombinant Viral Particles
App 20200225139 - O'RIORDAN; Catherine R. ; et al. | 2020-07-16 |
Integrated continuous manufacturing of therapeutic protein drug substances
Grant 10,711,034 - Konstantinov , et al. | 2020-07-14 |
Oligosaccharide-protein Conjugates
App 20200216485 - AVILA; Luis Z. ; et al. | 2020-07-09 |
SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
App 20200216844 - Akinc; Akin ; et al. | 2020-07-09 |
VARIANT RNAi
App 20200216848 - O'RIORDAN; Catherine R. ; et al. | 2020-07-09 |
Methods for purification of recombinant AAV vectors
Grant 10,696,952 - Sheldon , et al. June 30, 2 | 2020-06-30 |
Methods For Treating Proteinopathies
App 20200197374 - CHENG; Seng H. ; et al. | 2020-06-25 |
Inhibiting or downregulating glycogen synthase by creating premature stop codons using antisense oligonucleotides
Grant 10,682,423 - Nelson , et al. | 2020-06-16 |
Method Of Preparing Glucosylceramide Synthase Inhibitors
App 20200181137 - SIEGEL; Craig S. ; et al. | 2020-06-11 |
Methods And Compositions For Treating A Bleeding Event In A Subject Having Hemophilia
App 20200163987 - AKINC; Akin | 2020-05-28 |
Methods For Producing Preparations Of Recombinant Aav Virions Substantially Free Of Empty Capsids
App 20200157566 - QU; Guang ; et al. | 2020-05-21 |
Methods For Introducing Mannose 6-phosphate And Other Oligosaccharides Onto Glycoproteins And Its Application Thereof
App 20200147184 - ZHU; Yunxiang | 2020-05-14 |
Method of identifying risk for thyroid disorder
Grant 10,648,986 - Margolin | 2020-05-12 |
Methods of controlling the formation of disulfide bonds in protein solutions
Grant 10,647,777 - Brower , et al. | 2020-05-12 |
Hyperglycosylated Binding Polypeptides
App 20200140564 - PAN; Clark ; et al. | 2020-05-07 |
Compositions and methods for treating and preventing macular degeneration
Grant 10,640,771 - Wadsworth , et al. | 2020-05-05 |
Scfv-fc Dimers That Bind Transforming Growth Factor-beta1 With High Affinity, Avidity And Specificity
App 20200131258 - Qiu; Huawei ; et al. | 2020-04-30 |
Elution Of Biomolecules From Multi-modal Resins Using Mes And Mops As Mobile Phase Modifiers
App 20200131493 - Godawat; Rahul ; et al. | 2020-04-30 |
Gene therapy for neurometabolic disorders
Grant 10,632,213 - Passini , et al. | 2020-04-28 |
Treatment of myocardial infarction using TGF-.beta. antagonists
Grant 10,633,437 - Akita , et al. | 2020-04-28 |
Biomarkers Of Proteopathies And Uses Thereof
App 20200124624A1 - | 2020-04-23 |
VARIANT RNAi
App 20200109401 - STANEK; Lisa M. ; et al. | 2020-04-09 |
Gene Therapy For Amyotrophic Lateral Sclerosis And Other Spinal Cord Disorders
App 20200101138 - DODGE; James ; et al. | 2020-04-02 |
Polynucleotide Agents Targeting Serpinc1 (at3) And Methods Of Use Thereof
App 20200102560 - Hinkle; Gregory | 2020-04-02 |
Udp Glycosyltransferase Inhibitors And Methods Of Use
App 20200102324 - LIM; Sungtaek ; et al. | 2020-04-02 |
Method of preparing glucosylceramide synthase inhibitors
Grant 10,604,518 - Siegel , et al. | 2020-03-31 |
Microcarrier Perfusion Culturing Methods And Uses Thereof
App 20200080063 - Yang; Jianguo ; et al. | 2020-03-12 |
Gene Therapy For Niemann-pick Disease Type A
App 20200080066 - PASSINI; Marco A. ; et al. | 2020-03-12 |
Multi-dose compositions containing an antimicrobial polyamide or octenidine preservative
Grant 10,583,154 - Rigaut , et al. | 2020-03-10 |
Sterile Chromatography Resin And Use Thereof In Manufacturing Processes
App 20200069822 - Patil; Rohan ; et al. | 2020-03-05 |
Methods of perfusion culturing using a shake flask and microcarriers
Grant 10,577,583 - Yang , et al. | 2020-03-03 |
Seed train processes and uses thereof
Grant 10,570,367 - Bruninghaus , et al. Feb | 2020-02-25 |
Glucosylceramide Synthase Inhibitors
App 20200048266 - BOURQUE; Elyse ; et al. | 2020-02-13 |
Gene Therapy For Retinitis Pigmentosa
App 20200046851 - O'RIORDAN; Catherine ; et al. | 2020-02-13 |
Anti-Human CD52 Immunoglobulins
App 20200040091 - Roberts; Bruce L. ; et al. | 2020-02-06 |
Early Post-transfection Isolation Of Cells (epic) For Biologics Production
App 20200018682 - Cairns; Victor R. ; et al. | 2020-01-16 |
Oligosaccharides Comprising An Aminooxy Group And Conjugates Thereof
App 20200010825 - ZHU; Yunxiang ; et al. | 2020-01-09 |
Chemokine Receptor Binding Heterocyclic Compounds With Enhanced Efficacy
App 20200000774 - Bridger; Gary J. ; et al. | 2020-01-02 |
Methods for Treating Osteogenesis Imperfecta
App 20190389943 - Lee; Brendan ; et al. | 2019-12-26 |
Multiple Oligonucleotide Moieties On Peptide Carrier
App 20190388547 - WEEDEN; Timothy E. ; et al. | 2019-12-26 |
ScFv-Fc dimers that bind transforming growth factor-BETA1 with high affinity, avidity and specificity
Grant 10,508,146 - Qiu , et al. Dec | 2019-12-17 |
Combination therapy for treating breast cancer
Grant 10,507,242 - Harper , et al. Dec | 2019-12-17 |
Hyperglycosylated binding polypeptides
Grant 10,494,439 - Pan , et al. De | 2019-12-03 |
Fusion Proteins Comprising Pdgf And Vegf Binding Portions And Methods Of Using Thereof
App 20190345223 - Pechan; Peter ; et al. | 2019-11-14 |
Perfusion Bioreactor With Filtration Systems
App 20190338238 - Lu; Jiuyi ; et al. | 2019-11-07 |
Oligosaccharide-protein conjugates
Grant 10,464,962 - Avila , et al. No | 2019-11-05 |
Slow Intraventricular Delivery
App 20190328682 - DODGE; James C. ; et al. | 2019-10-31 |
Quinazoline derivatives as VEGF inhibitors
Grant 10,457,664 - Thomas , et al. Oc | 2019-10-29 |
Synthesis Of Udp-glucose: N-acylsphingosine Glucosyltransferase Inhibitors
App 20190322649 - HIRTH; Bradford H. ; et al. | 2019-10-24 |
Variant RNAi
Grant 10,450,563 - Stanek , et al. Oc | 2019-10-22 |
Aav Virions With Decreased Immunoreactivity And Uses Therefor
App 20190314526 - ARBETMAN; Alejandra E. ; et al. | 2019-10-17 |
Novel Beta-actin And Rps21 Promoters And Uses Thereof
App 20190300880 - ESTES; Scott D. ; et al. | 2019-10-03 |
Analytical ultracentrifugation for characterization of recombinant viral particles
Grant 10,429,288 - O'Riordan , et al. October 1, 2 | 2019-10-01 |
Microcarrier perfusion culturing methods and uses thereof
Grant 10,421,949 - Yang , et al. September 24, 2 | 2019-09-24 |
Methods for Improvidng Cell Viability In A Production Bioreactor
App 20190285617 - Wang; Jonathan ; et al. | 2019-09-19 |
Multivariate Spectral Analysis and Monitoring for Biomanufacturing
App 20190272894 - Wasalathanthri; Dhanuka Pulasthi ; et al. | 2019-09-05 |
Chemical Process for the Synthesis of 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)qu- inazoline
App 20190263782 - Blixt; Jorgen ; et al. | 2019-08-29 |
Fc Variants With Enhanced Binding To Fcrn And Prolonged Half-life
App 20190263934 - Qiu; Huawei ; et al. | 2019-08-29 |
Gene therapy for retinitis pigmentosa
Grant 10,383,953 - O'Riordan , et al. A | 2019-08-20 |
Peptide analogs of alpha-melanocyte stimulating hormone
Grant 10,385,108 - Perricone , et al. A | 2019-08-20 |
Methods for treating osteogenesis imperfecta
Grant 10,377,819 - Lee , et al. A | 2019-08-13 |
Pharmaceutical Compositions
App 20190240252 - HOLMES-FARLEY; Stephen Randall ; et al. | 2019-08-08 |
Gene therapy for neurodegenerative disorders
Grant 10,369,193 - Passini , et al. | 2019-08-06 |
Methods For Enhanced Removal Of Impurities During Protein A Chromatography
App 20190233468 - BEIGIE; Carl A. | 2019-08-01 |
Site-specific Antibody-drug Conjugation Through Glycoengineering
App 20190233531 - Pan; Clark ; et al. | 2019-08-01 |
Methods For The Quantitation Of Polypeptides
App 20190234963 - Morgan; Christopher ; et al. | 2019-08-01 |
Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins and applications thereof
Grant 10,363,291 - Zhu | 2019-07-30 |
High Density Cell Banking Methods
App 20190223433 - JIN; Xiaoxia ; et al. | 2019-07-25 |
Methods To Mobilize Progenitor/stem Cells
App 20190216773 - BRIDGER; Gary J. ; et al. | 2019-07-18 |
Chemical process for the synthesis of 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)qu- inazoline
Grant 10,344,015 - Blixt , et al. July 9, 2 | 2019-07-09 |
Polynucleotide agents targeting Serpinc1 (AT3) and methods of use thereof
Grant 10,344,278 - Hinkle July 9, 2 | 2019-07-09 |
Methods For Treating Gaucher Disease
App 20190183844 - LI; Jing ; et al. | 2019-06-20 |
Tropomyosin-related Kinase (trk) Inhibitors
App 20190183903 - KANE, JR.; John L. ; et al. | 2019-06-20 |
Chemokine receptor binding heterocyclic compounds with enhanced efficacy
Grant 10,322,111 - Bridger , et al. | 2019-06-18 |
Antibodies to TGF-Beta
App 20190177406 - Ledbetter; Steven R. ; et al. | 2019-06-13 |
Early post-transfection isolation of cells (EPIC) for biologics production
Grant 10,317,329 - Cairns , et al. | 2019-06-11 |
Nucleotide sequences encoding VEGF antagonist compositions of FLT-1 and uses thereof
Grant 10,308,917 - Stefano , et al. | 2019-06-04 |
Dose Escalation Enzyme Replacement Therapy For Treating Acid Sphingomyelinase Deficiency
App 20190151419 - Schuchman; Edward H. ; et al. | 2019-05-23 |
.beta.-actin promoters and uses thereof
Grant 10,273,479 - Estes , et al. | 2019-04-30 |
Inhibiting Or Downregulating Glycogen Synthase By Creating Premature Stop Codons Using Antisense Oligonucleotides
App 20190117794 - NELSON; Carol A. ; et al. | 2019-04-25 |
Anti-cxcr3 Antibodies And Methods Of Use Thereof
App 20190119391 - Youd; Michele ; et al. | 2019-04-25 |
Enhanced Delivery Of Viral Particles To The Striatum And Cortex
App 20190111157 - STANEK; Lisa M. ; et al. | 2019-04-18 |
Metabolically Activated Recombinant Viral Vectors And Methods For Their Preparation And Use
App 20190100773A1 - | 2019-04-04 |
Intraventricular Enzyme Delivery For Lysosomal Storage Diseases
App 20190083582A1 - | 2019-03-21 |
Method of treating polycystic kidney diseases with ceramide derivatives
Grant 10,220,039 - Natoli , et al. | 2019-03-05 |
Pharmaceutical formulations of tropomyosin related kinase (Trk) inhibitors
Grant 10,219,998 - Lieberman , et al. | 2019-03-05 |
Method Of Treating Primary Focal Segmental Glomerulosclerosis
App 20190062416A1 - | 2019-02-28 |
Site-specific antibody-drug conjugation through glycoengineering
Grant 10,214,589 - Pan , et al. Feb | 2019-02-26 |
Treatment of synucleinopathies
Grant 10,213,494 - Schlossmacher , et al. Feb | 2019-02-26 |
High density cell banking methods
Grant 10,188,099 - Jin , et al. Ja | 2019-01-29 |
Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency
Grant 10,188,705 - Schuchman , et al. Ja | 2019-01-29 |
Nucleic acids encoding fusion proteins comprising PDGF and VEGF binding portions and methods of using thereof
Grant 10,183,983 - Pechan , et al. Ja | 2019-01-22 |
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