loadpatents
Patent applications and USPTO patent grants for Behlke; Mark Aaron.The latest application filed is for "dna polymerase mutants having enhanced template discrimination activity".
Patent | Date |
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Protein mutants that enhance the DNA cleavage activity of Acidaminococcus sp. CPF1 Grant 11,447,758 - Zhang , et al. September 20, 2 | 2022-09-20 |
S. pyogenes CAS9 mutant genes and polypeptides encoded by same Grant 11,427,818 - Vakulskas , et al. August 30, 2 | 2022-08-30 |
S. pyogenes Cas9 mutant genes and polypeptides encoded by same Grant 11,242,542 - Vakulskas , et al. February 8, 2 | 2022-02-08 |
Dna Polymerase Mutants Having Enhanced Template Discrimination Activity App 20220010346 - Behlke; Mark Aaron ;   et al. | 2022-01-13 |
Crispr/cpf1 Systems And Methods App 20220002693 - Behlke; Mark Aaron ;   et al. | 2022-01-06 |
Methods For Variant Detection App 20210395799 - Dobosy; Joseph ;   et al. | 2021-12-23 |
CRISPR/CPF1 systems and methods Grant 11,136,567 - Behlke , et al. October 5, 2 | 2021-10-05 |
Methods For Variant Detection App 20210285033 - CHEN; Caifu ;   et al. | 2021-09-16 |
Methods For Variant Detection App 20210202034 - DOBOSY; Joseph ;   et al. | 2021-07-01 |
DNA polymerase mutants having enhanced template discrimination activity Grant 10,982,247 - Behlke , et al. April 20, 2 | 2021-04-20 |
S. Pyogenes Cas9 Mutant Genes And Polypeptides Encoded By Same App 20210062187 - Vakulskas; Christopher Anthony ;   et al. | 2021-03-04 |
Methods for variant detection Grant 10,886,006 - Dobosy , et al. January 5, 2 | 2021-01-05 |
Cleavable hairpin primers Grant 10,858,699 - Walder , et al. December 8, 2 | 2020-12-08 |
CRISPR-based compositions and methods of use Grant 10,767,176 - Collingwood , et al. Sep | 2020-09-08 |
S. pyogenes CAS9 mutant genes and polypeptides encoded by same Grant 10,717,978 - Vakulskas , et al. | 2020-07-21 |
Novel Mutations That Enhance The Dna Cleavage Activity Of Acidaminococcus Sp. Cpf1 App 20200109382 - Zhang; Liyang ;   et al. | 2020-04-09 |
Methods For Variant Detection App 20190221290 - Dobosy; Joseph ;   et al. | 2019-07-18 |
Methods For Variant Detection App 20190218611 - Dobosy; Joseph ;   et al. | 2019-07-18 |
T.sub.m-enhanced blocking oligonucleotides and baits for improved target enrichment and reduced off-target selection Grant 10,266,889 - Behlke , et al. | 2019-04-23 |
RNase H-based assays utilizing modified RNA monomers Grant 10,227,641 - Walder , et al. | 2019-03-12 |
RNase H-Based Assays Utilizing Modified RNA Monomers App 20190002865 - Walder; Joseph Alan ;   et al. | 2019-01-03 |
S. Pyogenes Cas9 Mutant Genes And Polypeptides Encoded By Same App 20180320201 - Vakulskas; Christopher Anthony ;   et al. | 2018-11-08 |
Modifications for antisense compounds Grant 10,087,445 - Behlke , et al. October 2, 2 | 2018-10-02 |
Crispr/cpf1 Systems And Methods App 20180187176 - Behlke; Mark Aaron ;   et al. | 2018-07-05 |
Crispr-based Compositions And Methods Of Use App 20180179523 - Collingwood; Michael Allen ;   et al. | 2018-06-28 |
S. Pyogenes Cas9 Mutant Genes And Polypeptides Encoded By Same App 20180100148 - Vakulskas; Christopher Anthony ;   et al. | 2018-04-12 |
Cleavable Hairpin Primers App 20180057868 - Walder; Joseph A. ;   et al. | 2018-03-01 |
Microarray System With Improved Sequence Specificity App 20170369936 - Gunning; Kerry B. ;   et al. | 2017-12-28 |
RNase H-Based Assays Utilizing Modified RNA Monomers App 20170355978 - Walder; Joseph Alan ;   et al. | 2017-12-14 |
CRISPR-based compositions and methods of use Grant 9,840,702 - Collingwood , et al. December 12, 2 | 2017-12-12 |
Methods For Variant Detection App 20170260583 - Dobosy; Joseph ;   et al. | 2017-09-14 |
Methods For Variant Detection App 20170253925 - Dobosy; Joseph ;   et al. | 2017-09-07 |
Modifications for Antisense Compounds App 20170204412 - Behlke; Mark Aaron ;   et al. | 2017-07-20 |
Methods For Variant Detection App 20170145486 - CHEN; Caifu ;   et al. | 2017-05-25 |
RNase H-based assays utilizing modified RNA monomers Grant 9,644,198 - Walder , et al. May 9, 2 | 2017-05-09 |
Dna Polymerase Mutants Having Enhanced Template Discrimination Activity App 20170114379 - Behlke; Mark Aaron ;   et al. | 2017-04-27 |
Tm-enhanced Blocking Oligonucleotides And Baits For Improved Target Enrichment And Reduced Off-target Selection App 20170114404 - Behlke; Mark Aaron ;   et al. | 2017-04-27 |
Tm-ENHANCED BLOCKING OLIGONUCLEOTIDES AND BAITS FOR IMPROVED TARGET ENRICHMENT AND REDUCED OFF-TARGET SELECTION App 20170096706 - Behlke; Mark Aaron ;   et al. | 2017-04-06 |
Modified Rnase H Enzymes And Their Uses App 20170044507 - WALDER; Joseph Alan ;   et al. | 2017-02-16 |
Crispr-based Compositions And Methods Of Use App 20170044535 - Collingwood; Michael Allen ;   et al. | 2017-02-16 |
Crispr-based Compositions And Methods Of Use App 20170044537 - Collingwood; Michael Allen ;   et al. | 2017-02-16 |
Crispr-based Compositions And Methods Of Use App 20170044536 - Collingwood; Michael Allen ;   et al. | 2017-02-16 |
Fluorescence quenching azo dyes, their methods of preparation and use Grant 9,540,515 - Laikhter , et al. January 10, 2 | 2017-01-10 |
Modifications for antisense compounds Grant 9,506,057 - Behlke , et al. November 29, 2 | 2016-11-29 |
Modifications for antisense compounds Grant 9,506,059 - Behlke , et al. November 29, 2 | 2016-11-29 |
RNase H-based assays utilizing modified RNA monomers Grant 9,434,988 - Behlke , et al. September 6, 2 | 2016-09-06 |
Crispr-based Compositions And Methods Of Use App 20160177304 - Collingwood; Michael Allen ;   et al. | 2016-06-23 |
Rnase H-based Assays Utilizing Modified Rna Monomers App 20150307917 - Walder; Joseph Alan ;   et al. | 2015-10-29 |
Rnase H-based Assays Utilizing Modified Rna Monomers App 20150225782 - WALDER; Joseph Alan ;   et al. | 2015-08-13 |
Methods To Capture And/or Remove Highly Abundant Rnas From A Heterogenous Rna Sample App 20150218620 - Behlke; Mark Aaron ;   et al. | 2015-08-06 |
Dna Polymerase Mutants Having Enhanced Template Discrimination Activity App 20150191707 - Behlke; Mark Aaron ;   et al. | 2015-07-09 |
Microarray System With Improved Sequence Specificity App 20150176067 - Gunning; Kerry B. ;   et al. | 2015-06-25 |
Microarray system with improved sequence specificity Grant 8,945,928 - Gunning , et al. February 3, 2 | 2015-02-03 |
Modifications for Antisense Compounds App 20150011744 - Behlke; Mark Aaron ;   et al. | 2015-01-08 |
RNase H-based assays utilizing modified RNA monomers Grant 8,911,948 - Walder , et al. December 16, 2 | 2014-12-16 |
Modified Rnase H Enzymes And Their Uses App 20140255925 - WALDER; Joseph Alan ;   et al. | 2014-09-11 |
RNase H-Based Assays Utilizing Modified RNA Monomers App 20140162249 - Behlke; Mark Aaron ;   et al. | 2014-06-12 |
RNase H-Based Assays Utilizing Modified RNA Monomers App 20140106433 - Walder; Joseph Alan ;   et al. | 2014-04-17 |
Tm-enhanced Blocking Oligonucleotides And Baits For Improved Target Enrichment And Reduced Off-target Selection App 20140031240 - Behlke; Mark Aaron ;   et al. | 2014-01-30 |
Microarray System With Improved Sequence Specificity App 20130316927 - Gunning; Kerry B. ;   et al. | 2013-11-28 |
Modified Rnase H Enzymes And Their Uses App 20130288245 - WALDER; Joseph Alan ;   et al. | 2013-10-31 |
Modifications for Antisense Compounds App 20130236967 - Behlke; Mark Aaron ;   et al. | 2013-09-12 |
Fluorescence Quenching Azo Dyes, Their Methods Of Preparation And Use App 20130116415 - Laikhter; Andrei ;   et al. | 2013-05-09 |
Methods for amplifying polymeric nucleic acids Grant 8,399,197 - Behlke , et al. March 19, 2 | 2013-03-19 |
Fluorescence quenching azo dyes, their methods of preparation and use Grant 8,377,641 - Laikhter , et al. February 19, 2 | 2013-02-19 |
RNase H-Based Assays Utilizing Modified RNA Monomers App 20120258455 - Behlke; Mark Aaron ;   et al. | 2012-10-11 |
Method for Estimating a Melting Temperature of a Nucleic Acid in Buffers Containing Magnesium Ions App 20120123751 - Owczarzy; Richard ;   et al. | 2012-05-17 |
Modifications for Antisense Compounds App 20120108799 - Behlke; Mark Aaron ;   et al. | 2012-05-03 |
Microarray System With Improved Sequence Specificity App 20120077712 - Gunning; Kerry B. ;   et al. | 2012-03-29 |
Fluorescence Quenching Azo Dyes, Their Methods Of Preparation And Use App 20120064633 - Laikhter; Andrei ;   et al. | 2012-03-15 |
Di-alpha amino anthraquinone compositions Grant 8,114,979 - Laikhter , et al. February 14, 2 | 2012-02-14 |
Fluorescence quenching azo dyes, their methods of preparation and use Grant 8,084,588 - Laikhter , et al. December 27, 2 | 2011-12-27 |
Microarray system with improved sequence specificity Grant 8,067,164 - Gunning , et al. November 29, 2 | 2011-11-29 |
Method for estimating a melting temperature of a nucleic acid in buffers containing magnesium ions Grant 8,055,451 - Owczarzy , et al. November 8, 2 | 2011-11-08 |
Method Of Detecting Fluorescence App 20110060150 - Laikhter; Andrei ;   et al. | 2011-03-10 |
Methods of detecting fluorescence with anthraquinone quencher dyes Grant 7,803,536 - Behlke , et al. September 28, 2 | 2010-09-28 |
Rnase H-based Assays Utilizing Modified Rna Monomers App 20100167353 - Walder; Joseph Alan ;   et al. | 2010-07-01 |
RNA interference in respiratory epithelial cells Grant 7,687,475 - McCray , et al. March 30, 2 | 2010-03-30 |
Rnase H-based Assays Utilizing Modified Rna Monomers App 20090325169 - Walder; Joseph Alan ;   et al. | 2009-12-31 |
Method For Estimating A Melting Temperature Of A Nucleic Acid In Buffers Containing Magnesium Ions App 20090198453 - Owczarzy; Richard ;   et al. | 2009-08-06 |
Microarray System With Improved Sequence Specificity App 20090143243 - Gunning; Kerry B. ;   et al. | 2009-06-04 |
Fluorescence Quenching Azo Dyes, Their Methods Of Preparation And Use App 20090053821 - Laikhter; Andrei ;   et al. | 2009-02-26 |
RNA interference in respiratory epithelial cells App 20090029934 - McCray; Paul B. ;   et al. | 2009-01-29 |
Fluorescence quenching azo dyes, their methods of preparation and use Grant 7,439,341 - Laikhter , et al. October 21, 2 | 2008-10-21 |
RNA interference in respiratory epitheial cells Grant 7,297,786 - McCray , et al. November 20, 2 | 2007-11-20 |
Compositions and methods for visual ribonuclease detection assays Grant 7,276,337 - Walder , et al. October 2, 2 | 2007-10-02 |
Primer extension methods for production of high specific activity nucleic acid probes Grant 7,135,284 - Behlke , et al. November 14, 2 | 2006-11-14 |
Polynomial amplification of nucleic acids Grant 7,112,406 - Behlke , et al. September 26, 2 | 2006-09-26 |
RNA interference in respiratory epitheial cells App 20060084620 - McCray; Paul B. ;   et al. | 2006-04-20 |
Fluorescence quenching azo dyes, their methods of preparation and use App 20050112673 - Laikhter, Andrei ;   et al. | 2005-05-26 |
Methods and systems for estimating the melting temperature (TM) for polynucleotide molecules Grant 6,889,143 - Behlke , et al. May 3, 2 | 2005-05-03 |
Polynomial amplification of nucleic acids App 20040248095 - Behlke, Mark Aaron ;   et al. | 2004-12-09 |
Compositions and methods for visual ribonuclease detection assays Grant 6,773,885 - Walder , et al. August 10, 2 | 2004-08-10 |
Compositions and methods for visual ribonuclease detection assays App 20040137479 - Walder, Joseph Alan ;   et al. | 2004-07-15 |
Methods and systems for estimating the melting temperature (TM) for polynucleotide molecules App 20040115705 - Behlke, Mark Aaron ;   et al. | 2004-06-17 |
Anthraquinone quencher dyes, their methods of preparation and use App 20040110308 - Laikhter, Andrei ;   et al. | 2004-06-10 |
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