loadpatents
Patent applications and USPTO patent grants for Aoki; Kei Roger.The latest application filed is for "immuno-based botulinum toxin serotype a activity assays".
Patent | Date |
---|---|
Immuno-based botulinum toxin serotype A activity assays Grant 11,332,518 - Fernandez-Salas , et al. May 17, 2 | 2022-05-17 |
Immuno-based Botulinum Toxin Serotype A Activity Assays App 20220144925 - Fernandez-Salas; Ester ;   et al. | 2022-05-12 |
Immuno-based botulinum toxin serotype A activity assays Grant 11,261,240 - Fernandez-Salas , et al. March 1, 2 | 2022-03-01 |
Immuno-based Botulinum Toxin Serotype A Activity Assays App 20210340229 - Fernandez-Salas; Ester ;   et al. | 2021-11-04 |
Immuno-based Botulinum Toxin Serotype A Activity Assays App 20210171614 - Fernandez-Salas; Ester ;   et al. | 2021-06-10 |
Degradable Clostridial Toxins App 20200190496 - Steward; Lance E. ;   et al. | 2020-06-18 |
Non-cytotoxic protein conjugates Grant 10,619,146 - Foster , et al. | 2020-04-14 |
Degradable clostridial toxins Grant 10,501,731 - Steward , et al. Dec | 2019-12-10 |
Degradable Clostridial Toxins App 20180119126 - Steward; Lance E. ;   et al. | 2018-05-03 |
Degradable clostridial toxins Grant 9,850,476 - Steward , et al. December 26, 2 | 2017-12-26 |
Non-cytotoxic Protein Conjugates App 20160369257 - FOSTER; Keith ;   et al. | 2016-12-22 |
Non-cytotoxic protein conjugates Grant 9,474,807 - Foster , et al. October 25, 2 | 2016-10-25 |
Degradable Clostridial Toxins App 20160201046 - Steward; Lance E. ;   et al. | 2016-07-14 |
Methods of treating urogenital-neurological disorders using modified Clostridial toxins Grant 9,370,548 - Brin , et al. June 21, 2 | 2016-06-21 |
Degradable Clostridial toxins Grant 9,297,003 - Steward , et al. March 29, 2 | 2016-03-29 |
Degradable clostridial toxins Grant 9,284,545 - Steward , et al. March 15, 2 | 2016-03-15 |
Degradable clostridial toxins Grant 9,279,116 - Steward , et al. March 8, 2 | 2016-03-08 |
Immuno-based botulinum toxin serotype A activity assays Grant 9,249,216 - Fernandez-Salas , et al. February 2, 2 | 2016-02-02 |
Fusion proteins Grant 9,243,301 - Foster , et al. January 26, 2 | 2016-01-26 |
Non-cytotoxic protein conjugates Grant 9,139,635 - Foster , et al. September 22, 2 | 2015-09-22 |
Non-cytotoxic protein conjugates Grant 9,012,195 - Foster , et al. April 21, 2 | 2015-04-21 |
Fusion proteins Grant 8,940,870 - Foster , et al. January 27, 2 | 2015-01-27 |
Non-cytotoxic Protein Conjugates App 20140294797 - FOSTER; Keith ;   et al. | 2014-10-02 |
Degradable clostridial toxins Grant 8,841,111 - Steward , et al. September 23, 2 | 2014-09-23 |
Degradable Clostridial Toxins App 20140227740 - STEWARD; LANCE E. ;   et al. | 2014-08-14 |
Degradable Clostridial Toxins App 20140220627 - STEWARD; LANCE E. ;   et al. | 2014-08-07 |
Non-cytotoxic protein conjugates Grant 8,778,634 - Foster , et al. July 15, 2 | 2014-07-15 |
Degradable Clostridial Toxins App 20140127783 - Steward; Lance E. ;   et al. | 2014-05-08 |
Degradable clostridial toxins Grant 8,697,413 - Steward , et al. April 15, 2 | 2014-04-15 |
Degradable clostridial toxins Grant 8,697,414 - Steward , et al. April 15, 2 | 2014-04-15 |
Degradable clostridial toxins Grant 8,685,692 - Steward , et al. April 1, 2 | 2014-04-01 |
Degradable clostridial toxins Grant 8,685,693 - Steward , et al. April 1, 2 | 2014-04-01 |
Fusion Proteins App 20140056870 - James; Peter ;   et al. | 2014-02-27 |
Modified Clostridial toxins with enhanced targeting capabilities for endogenous Clostridial toxin receptor systems Grant 8,623,999 - Steward , et al. January 7, 2 | 2014-01-07 |
Immuno-based botulinum toxin serotype A activity assays Grant 8,618,261 - Ester , et al. December 31, 2 | 2013-12-31 |
Degradable Clostridial Toxins App 20130330807 - Steward; Lance E. ;   et al. | 2013-12-12 |
Degradable Clostridial Toxins App 20130330806 - Steward; Lance E. ;   et al. | 2013-12-12 |
Non-cytotoxic protein conjugates Grant 8,603,779 - Foster , et al. December 10, 2 | 2013-12-10 |
Non-cytotoxic Protein Conjugates App 20130295643 - FOSTER; Keith ;   et al. | 2013-11-07 |
Degradable Clostridial Toxins App 20130288334 - Steward; Lance E. ;   et al. | 2013-10-31 |
Degradable Clostridial Toxins App 20130273633 - Steward; Lance E. ;   et al. | 2013-10-17 |
Treatment for cervical dystonia with the neurotoxic component of a botulinum toxin Grant 8,557,256 - Aoki , et al. October 15, 2 | 2013-10-15 |
Lipophilic dye-based FRET assays for clostridial toxin activity Grant 8,535,941 - Fernandez-Salas , et al. September 17, 2 | 2013-09-17 |
Methods Of Treating Cancer Using Opiod Retargeted Endopepidases App 20130230502 - Jacky; Birgitte P.S. ;   et al. | 2013-09-05 |
Methods of Treating Cancer Using Glucagon-Like Hormone Retargeted Endopepidases App 20130224178 - Jacky; Birgitte P.S. ;   et al. | 2013-08-29 |
Modified clostridial toxins with enhanced translocation capability and enhanced targeting activity Grant 8,518,417 - Steward , et al. August 27, 2 | 2013-08-27 |
Degradable clostridial toxins Grant 8,512,992 - Steward , et al. August 20, 2 | 2013-08-20 |
Modified Clostridial Toxins With Enhanced Translocation Capability And Enhanced Targeting Activity App 20130203148 - Steward; Lance E. ;   et al. | 2013-08-08 |
Methods of Treating Cancer Using Growth Factor Retargeted Endopeptidases App 20130195838 - JACKY; Birgitte P.S. ;   et al. | 2013-08-01 |
Degradable Clostridial Toxins App 20130196414 - Steward; Lance E. ;   et al. | 2013-08-01 |
Botulinum toxin screening assays Grant 8,497,081 - Fernandez-Salas , et al. July 30, 2 | 2013-07-30 |
Fusion Proteins App 20130189238 - FOSTER; Keith ;   et al. | 2013-07-25 |
Modified clostridial toxins with altered targeting capabilities for clostridial toxin target cells Grant 8,460,682 - Steward , et al. June 11, 2 | 2013-06-11 |
Fusion proteins Grant 8,399,401 - Foster , et al. March 19, 2 | 2013-03-19 |
Fusion proteins Grant 8,399,400 - Foster , et al. March 19, 2 | 2013-03-19 |
Immuno-based Botulinum Toxin Serotype A Activity Assays App 20130040368 - Fernandez-Salas; Ester ;   et al. | 2013-02-14 |
Neurotoxins with enhanced target specificity Grant 8,309,686 - Lin , et al. November 13, 2 | 2012-11-13 |
Activatable clostridial toxins Grant 8,273,358 - Steward , et al. September 25, 2 | 2012-09-25 |
Multivalent clostridial toxins Grant 8,273,865 - Steward , et al. September 25, 2 | 2012-09-25 |
Lipophilic Dye-based Fret Assays For Clostridial Toxin Activity App 20120231538 - Fernandez-Salas; Ester ;   et al. | 2012-09-13 |
Fusion Proteins App 20120230975 - Foster; Keith ;   et al. | 2012-09-13 |
Immuno-Based Botulinum Toxin Serotype A Activity Assays App 20120225436 - Fernandez-Salas; Ester ;   et al. | 2012-09-06 |
Botulinum toxin screening assays Grant 8,257,914 - Fernandez-Salas , et al. September 4, 2 | 2012-09-04 |
Inhibiting Aberrant Blood Vessel Formation Using Growth Factor Retargeted Endopeptidases App 20120207704 - Jacky; Birgitte P.S. ;   et al. | 2012-08-16 |
Non-cytotoxic Protein Conjugates App 20120207735 - FOSTER; Keith ;   et al. | 2012-08-16 |
Treatments Using PSMA Ligand Endopeptidases App 20120207742 - Jacky; Birgitte P.S. ;   et al. | 2012-08-16 |
Treating a Disease of Hyperproliferation Using Retargeted Endopeptidases App 20120207733 - Jacky; Birgitte P.S. ;   et al. | 2012-08-16 |
Inhibiting Aberrant Blood Vessel Formation Using Retargeted Endopeptidases App 20120207743 - Jacky; Birgitte P.S. ;   et al. | 2012-08-16 |
Methods of Inhibiting Aberrant Blood Vessel Formation Using Opioid Retargeted Endpeptidases App 20120207734 - Jacky; Birgitte P.S. ;   et al. | 2012-08-16 |
Treatment Of Pain App 20120189610 - Foster; Keith ;   et al. | 2012-07-26 |
Modified Clostridial Toxins with Enhanced Targeting Capabilities For Endogenous Clostridial Toxin Receptor Systems App 20120178140 - Steward; Lance E. ;   et al. | 2012-07-12 |
Botulinum toxin treatments Grant 8,216,995 - Aoki , et al. July 10, 2 | 2012-07-10 |
Leucine-based motif and clostridial neurotoxins Grant 8,206,723 - Steward , et al. June 26, 2 | 2012-06-26 |
Non-cytotoxic Protein Conjugates App 20120156186 - FOSTER; Keith ;   et al. | 2012-06-21 |
Immuno-based botulinum toxin serotype A activity assays Grant 8,198,034 - Fernandez-Salas , et al. June 12, 2 | 2012-06-12 |
Neurotoxins With Enhanced Target Specificity App 20120135495 - LIN; WEI-JEN ;   et al. | 2012-05-31 |
Non-cytotoxic protein conjugates Grant 8,187,834 - Foster , et al. May 29, 2 | 2012-05-29 |
Use of the neurotoxic component of a botulinum toxin for treating a spastic muscle Grant 8,187,612 - Aoki , et al. May 29, 2 | 2012-05-29 |
Immuno-based Botulinum Toxin Serotype A Activity Assays App 20120122128 - Fernandez-Salas; Ester ;   et al. | 2012-05-17 |
Fusion Proteins App 20120064059 - FOSTER; Keith ;   et al. | 2012-03-15 |
Non-cytotoxic Protein Conjugates App 20120058098 - FOSTER; Keith ;   et al. | 2012-03-08 |
Modified Clostridial Toxins with Altered Targeting Capabilities For Clostridial Toxin Target Cells App 20120052548 - Steward; Lance E. ;   et al. | 2012-03-01 |
Lipophilic dye-based fret assays for clostridal toxin activity Grant 8,124,357 - Fernandez-Salas , et al. February 28, 2 | 2012-02-28 |
Activatable clostridial toxins Grant 8,071,110 - Steward , et al. December 6, 2 | 2011-12-06 |
Degradable Clostridial Toxins App 20110294742 - STEWARD; LANCE E. ;   et al. | 2011-12-01 |
Fusion proteins Grant 8,067,200 - Foster , et al. November 29, 2 | 2011-11-29 |
Clostridial toxin activity assays Grant 8,067,231 - Fernandez-Salas , et al. November 29, 2 | 2011-11-29 |
Degradable Clostridial Toxins App 20110287517 - STEWARD; LANCE E. ;   et al. | 2011-11-24 |
FRET protease assays for clostridial toxins Grant 8,053,208 - Steward , et al. November 8, 2 | 2011-11-08 |
FRET protease assays for clostridial toxins Grant 8,053,209 - Steward , et al. November 8, 2 | 2011-11-08 |
Modified clostridial toxins with altered targeting capabilities for clostridial toxin target cells Grant 8,052,979 - Steward , et al. November 8, 2 | 2011-11-08 |
FRET protease assays for clostridial toxins Grant 8,048,643 - Steward , et al. November 1, 2 | 2011-11-01 |
Luminescence resonance energy transfer (LRET) assays for clostridial toxin activity Grant 8,022,172 - Williams , et al. September 20, 2 | 2011-09-20 |
Modified clostridial toxins with altered targeting capabilities for clostridial toxin target cells Grant 8,021,859 - Steward , et al. September 20, 2 | 2011-09-20 |
FRET protease assays for clostridial toxins Grant 8,013,113 - Steward , et al. September 6, 2 | 2011-09-06 |
Fret protease assays for clostridial toxins Grant 8,003,753 - Steward , et al. August 23, 2 | 2011-08-23 |
Assays of molecular or subcellular interactivity using depolarization after resonance transfer energy (DARET) Grant 7,998,749 - Gilmore , et al. August 16, 2 | 2011-08-16 |
Degradable clostridial toxins Grant 7,998,489 - Steward , et al. August 16, 2 | 2011-08-16 |
Modified clostridial toxins with enhanced translocation capabilities and altered targeting activity for clostridial toxin target cells Grant 7,993,656 - Steward , et al. August 9, 2 | 2011-08-09 |
Non-cytotoxic Protein Conjugates App 20110177053 - FOSTER; Keith ;   et al. | 2011-07-21 |
Optimizing Expression of Active Botulinum Toxin Type E App 20110111483 - STEWARD; LANCE E. ;   et al. | 2011-05-12 |
Methods of Treating Cancer Using Tachykinin Retargeted Endopepidases App 20110110911 - Jacky; Birgitte P.S. ;   et al. | 2011-05-12 |
Fusion Proteins App 20110091437 - Foster; Keith ;   et al. | 2011-04-21 |
Multivalent Clostridial Toxins App 20110070621 - Steward; Lance E. ;   et al. | 2011-03-24 |
Methods of Treating Cancer Using Glucagon-Like Hormone Retargeted Endopeptidases App 20110070212 - Jacky; Birgitte P.S. ;   et al. | 2011-03-24 |
Methods of Treating Cancer Using Galanin Retargeted Endopepidases App 20110070211 - JACKY; BIRGITTE P.S. ;   et al. | 2011-03-24 |
Methods Of Treating Cancer Using Neurotrophin Retargeted Endopeptidases App 20110070215 - Jacky; Birgitte P.S. ;   et al. | 2011-03-24 |
Methods of Treating Cancer Using Growth Factor Retargeted Endopeptidases App 20110070186 - Jacky; Birgitte P.S. ;   et al. | 2011-03-24 |
Methods of Treating Cancer Using Opioid Retargeted Endopepidases App 20110064713 - Jacky; Birgitte P.S. ;   et al. | 2011-03-17 |
Activatable clostridial toxins Grant 7,897,157 - Steward , et al. March 1, 2 | 2011-03-01 |
Degradable clostridial toxins Grant 7,892,565 - Steward , et al. February 22, 2 | 2011-02-22 |
Fusion Proteins App 20110027256 - FOSTER; Keith ;   et al. | 2011-02-03 |
Luminescence resonance energy transfer (LRET) assays for clostridial toxin activity Grant 7,846,722 - Williams , et al. December 7, 2 | 2010-12-07 |
Clostridial Neurotoxin Compositions And Modified Clostridial Neurotoxins App 20100280222 - Steward; Lance E. ;   et al. | 2010-11-04 |
Optimizing expression of active Botulinum Toxin type E Grant 7,825,233 - Steward , et al. November 2, 2 | 2010-11-02 |
Multivalent clostridial toxins Grant 7,811,584 - Steward , et al. October 12, 2 | 2010-10-12 |
Fusion Proteins App 20100247509 - Foster; Keith ;   et al. | 2010-09-30 |
Immuno-Based Botulinum Toxin Serotype A Activity Assays App 20100203559 - Ester; Fernandez-Salas ;   et al. | 2010-08-12 |
Activatable clostridial toxins Grant 7,749,514 - Steward , et al. July 6, 2 | 2010-07-06 |
Cell compositions useful for cell-based FRET assays for clostridial toxins Grant 7,749,759 - Fernandez-Salas , et al. July 6, 2 | 2010-07-06 |
Activatable clostridial toxins Grant 7,740,868 - Steward , et al. June 22, 2 | 2010-06-22 |
Fret Protease Assays For Clostridial Toxins App 20100151494 - Steward; Lance E. ;   et al. | 2010-06-17 |
Leucine-based motif and clostridial neurotoxins Grant 7,723,480 - Steward , et al. May 25, 2 | 2010-05-25 |
Fret protease assays for botulinum serotype A/E toxins Grant 7,718,766 - Steward , et al. May 18, 2 | 2010-05-18 |
Substrates useful for FRET protease assays for botulinum serotype A/E toxins Grant 7,709,608 - Steward , et al. May 4, 2 | 2010-05-04 |
Leucine-based motif and Clostridial neurotoxins Grant 7,705,125 - Steward , et al. April 27, 2 | 2010-04-27 |
Leucine-based motif and clostridial neurotoxins Grant 7,705,124 - Steward , et al. April 27, 2 | 2010-04-27 |
Leucine-based motif and clostridial neurotoxins Grant 7,691,974 - Steward , et al. April 6, 2 | 2010-04-06 |
Fluorescence Polarization Assays For Determining Clostridial Toxin Activity App 20100081155 - Williams; Dudley J. ;   et al. | 2010-04-01 |
Fluorescence Polarization Assays For Determining Clostridial Toxin Activity App 20100081156 - Williams; Dudley J. ;   et al. | 2010-04-01 |
Fret Protease Assays For Clostridial Toxins App 20100081158 - Steward; Lance E. ;   et al. | 2010-04-01 |
Fret Protease Assays For Clostridial Toxins App 20100081157 - Steward; Lance E. ;   et al. | 2010-04-01 |
Fret Protease Assays For Clostridial Toxins App 20100075358 - Steward; Lance E. ;   et al. | 2010-03-25 |
Fret Protease Assays For Clostridial Toxins App 20100075357 - Steward; Lance E. ;   et al. | 2010-03-25 |
Fret Protease Assays For Clostridial Toxins App 20100075346 - Steward; Lance E. ;   et al. | 2010-03-25 |
Substrates Useful For Fret Protease Assays For Botulinum Serotype A/e Txoins App 20100069610 - Steward; Lance E. ;   et al. | 2010-03-18 |
FRET protease assays for botulinum serotype A/E toxins Grant 7,678,550 - Steward , et al. March 16, 2 | 2010-03-16 |
Fluorescence polarization assays for determining clostridial toxin activity Grant 7,674,601 - Williams , et al. March 9, 2 | 2010-03-09 |
Fret Protease Assays For Botulinum Serotype A/e Toxins App 20100055727 - STEWARD; LANCE E. ;   et al. | 2010-03-04 |
Leucine-based motif and clostridial neurotoxins Grant 7,671,177 - Steward , et al. March 2, 2 | 2010-03-02 |
Modified Clostridial Toxins With Altered Targeting Capabilities For Clostridial Toxin Target Cells App 20100041098 - Steward; Lance E. ;   et al. | 2010-02-18 |
Fusion proteins Grant 7,659,092 - Foster , et al. February 9, 2 | 2010-02-09 |
Non-cytotoxic protein conjugates Grant 7,658,933 - Foster , et al. February 9, 2 | 2010-02-09 |
Botulinum toxin screening assays Grant 7,645,570 - Fernandez-Salas , et al. January 12, 2 | 2010-01-12 |
Fluorescence polarization assays for determining clostridial toxin activity Grant 7,638,294 - Williams , et al. December 29, 2 | 2009-12-29 |
Botulinum Toxin Screening Assays App 20090317839 - Fernandez-Salas; Ester ;   et al. | 2009-12-24 |
Fluorescence polarization assays for determining clostridial toxin activity Grant 7,635,574 - Williams , et al. December 22, 2 | 2009-12-22 |
Fluorescence polarization assays for determining clostridial toxin activity Grant 7,632,655 - Williams , et al. December 15, 2 | 2009-12-15 |
Modification of clostridial toxins for use as transport proteins Grant 7,628,992 - Dolly , et al. December 8, 2 | 2009-12-08 |
Botulinum Toxin Screening Assays App 20090263836 - FERNANDEZ-SALAS; ESTER ;   et al. | 2009-10-22 |
Botulinum toxin screening assays Grant 7,598,027 - Fernandez-Salas , et al. October 6, 2 | 2009-10-06 |
Leucine-based Motif And Clostridial Neurotoxins App 20090202591 - Steward; Lance E. ;   et al. | 2009-08-13 |
Clostridial Toxin Activity Assays App 20090191583 - Fernandez-Salas; Ester ;   et al. | 2009-07-30 |
Leucine-based motifs and enhanced biological persistence of clostridial neurotoxins Grant 7,534,863 - Steward , et al. May 19, 2 | 2009-05-19 |
Cell-Based Fluorescence Resonance Energy Transfer (FRET) Assays For Clostridial Toxins App 20090117572 - Fernandez-Salas; Ester ;   et al. | 2009-05-07 |
Methods Of Treating Urogenital-neurological Disorders Using Modified Clostridial Toxins App 20090117157 - Brin; Mitchell F. ;   et al. | 2009-05-07 |
Clostridial Neurotoxin Compositions and Modified Clostridial Neurotoxins App 20090118475 - Steward; Lance E. ;   et al. | 2009-05-07 |
Methods Of Treating Chronic Neurogenic Inflammation Using Modified Clostridial Toxins App 20090104234 - Francis; Joseph ;   et al. | 2009-04-23 |
Multivalent Clostridial toxin derivatives and methods of their use Grant 7,514,088 - Steward , et al. April 7, 2 | 2009-04-07 |
Activatable Clostridial Toxins App 20090069238 - Steward; Lance E. ;   et al. | 2009-03-12 |
Fret Protease Assays For Botulinum Serotype A/e Toxins App 20090053746 - Steward; Lance E. ;   et al. | 2009-02-26 |
FRET protease assays for botulinum serotype A/E toxins Grant 7,495,069 - Steward , et al. February 24, 2 | 2009-02-24 |
Multivalent Clostridial Toxins App 20090048431 - Steward; Lance E. ;   et al. | 2009-02-19 |
Modified botulinum neurotoxins Grant 7,491,799 - Steward , et al. February 17, 2 | 2009-02-17 |
Fret Protease Assays For Clostridial Toxins App 20090042231 - STEWARD; LANCE E. ;   et al. | 2009-02-12 |
Fusion Proteins App 20090035822 - Foster; Keith ;   et al. | 2009-02-05 |
Degradable Clostridial Toxins App 20090023901 - Steward; Lance E. ;   et al. | 2009-01-22 |
Optimizing Expression Of Active Botulinum Toxin Type A App 20090023198 - Gilmore; Marcella A. ;   et al. | 2009-01-22 |
Activatable Clostridial Toxins App 20090018081 - Steward; Lance E. ;   et al. | 2009-01-15 |
Activatable Clostridial Toxins App 20090004224 - Steward; Lance E. ;   et al. | 2009-01-01 |
Toxin Compounds With Enhanced Membrane Translocation Characteristics App 20090004225 - Fernandez-Salas; Ester ;   et al. | 2009-01-01 |
Activatable Clostridial Toxins App 20090005313 - Steward; Lance E. ;   et al. | 2009-01-01 |
Fluorescence Polarization Assays For Determining Clostridial Toxin Activity App 20080305510 - Williams; Dudley J. ;   et al. | 2008-12-11 |
Fluorescence Polarization Assays For Determining Clostridial Toxin Activity App 20080305509 - Williams; Dudley J. ;   et al. | 2008-12-11 |
Fluorescence Polarization Assays For Determining Clostridial Toxin Activity App 20080293084 - Williams; Dudley J. ;   et al. | 2008-11-27 |
Fluorescence Polarization Assays For Determining Clostridial Toxin Activity App 20080293085 - Williams; Dudley J. ;   et al. | 2008-11-27 |
Neurotoxins with enhanced target specificity Grant 7,456,272 - Lin , et al. November 25, 2 | 2008-11-25 |
Modified Clostridial Toxins With Enhanced Translocation Capabilities And Altered Targeting Activity For Clostridial Toxin Target Cells App 20080241881 - Steward; Lance E. ;   et al. | 2008-10-02 |
Activatable Clostridial Toxins App 20080221012 - Steward; Lance E. ;   et al. | 2008-09-11 |
Luminescence Resonance Energy Transfer (lret) Assays For Clostridial Toxin Activity App 20080220456 - Williams; Dudley J. ;   et al. | 2008-09-11 |
Leucine-based Motif And Clostridial Neurotoxins App 20080214781 - Steward; Lance E. ;   et al. | 2008-09-04 |
Leucine-based Motif And Clostridial Neurotoxins App 20080194797 - Steward; Lance E. ;   et al. | 2008-08-14 |
Non-Cytotoxic Protein Conjugates App 20080187960 - Foster; Keith ;   et al. | 2008-08-07 |
Botulinum Toxin Screening Assays App 20080182799 - Fernandez-Salas; Ester ;   et al. | 2008-07-31 |
Leucine-based Motif And Clostridial Neurotoxins App 20080177042 - Steward; Lance E. ;   et al. | 2008-07-24 |
Fret Protease Assays For Botulinum Serotype A/e Toxins App 20080176336 - Steward; Lance E. ;   et al. | 2008-07-24 |
Leucine-based Motif And Clostridial Neurotoxins App 20080177037 - Steward; Lance E. ;   et al. | 2008-07-24 |
Leucine-based Motif And Clostridial Neurotoxins App 20080177041 - STEWARD; LANCE E. ;   et al. | 2008-07-24 |
Fluorescence polarization assays for determining clostridial toxin activity Grant 7,399,607 - Williams , et al. July 15, 2 | 2008-07-15 |
Lipophilic Dye-Based Fret Assays for Clostridal Toxin Activity App 20080160561 - Fernandez-Salas; Ester ;   et al. | 2008-07-03 |
Modified Clostridial Toxins With Altered Targeting Capabilities For Clostridial Toxin Target Cells App 20080161543 - Steward; Lance E. ;   et al. | 2008-07-03 |
Activatable Clostridial Toxins App 20080161226 - Steward; Lance E. ;   et al. | 2008-07-03 |
Leucine-based motif and Clostridial neurotoxins Grant 7,393,925 - Steward , et al. July 1, 2 | 2008-07-01 |
Fret Protease Assays For Botulinum Serotype A/e Toxins App 20080146786 - Steward; Lance E. ;   et al. | 2008-06-19 |
Neuropathic Pain Treatment Method App 20080138364 - Aoki; Kei Roger ;   et al. | 2008-06-12 |
Optimizing Expression Of Active BotulinumToxin Type E App 20080138893 - Steward; Lance E. ;   et al. | 2008-06-12 |
Methods for treating pain associated with arthritis Grant 7,381,700 - Aoki , et al. June 3, 2 | 2008-06-03 |
Method for treating a trigeminal neuralgia by peripheral administration of a neurotoxin Grant 7,374,769 - Aoki , et al. May 20, 2 | 2008-05-20 |
Modified Clostridial Toxins With Enhanced Targeting Capabilities For Endogenous Clostridial Toxin Receptor Systems App 20080096248 - Steward; Lance E. ;   et al. | 2008-04-24 |
Treatment of a facial pain by peripheral administration of a neurotoxin Grant 7,361,358 - Aoki , et al. April 22, 2 | 2008-04-22 |
Fluorescence Resonance Energy Transfer (fret) Assays For Clostridial Toxin Activity App 20080064054 - Fernandez-Salas; Ester ;   et al. | 2008-03-13 |
Optimizing Expression of Active Botulinum Toxin Type A App 20080057575 - Fernandez-Salas; Ester G. ;   et al. | 2008-03-06 |
Fret protease assays for clostridial toxins Grant 7,332,567 - Steward , et al. February 19, 2 | 2008-02-19 |
Fret Protease Assays For Clostridial Toxins App 20080038756 - Steward; Lance E. ;   et al. | 2008-02-14 |
Activatable Clostridial Toxins App 20080032930 - Steward; Lance E. ;   et al. | 2008-02-07 |
Activatable Clostridial Toxins App 20080032931 - Steward; Lance E. ;   et al. | 2008-02-07 |
Fret Protease Assays For Clostridial Toxins App 20080032318 - Steward; Lance E. ;   et al. | 2008-02-07 |
Methods And Compositions For The Treatment Of Pancreatitis App 20080025994 - Steward; Lance E. ;   et al. | 2008-01-31 |
Botulinum Toxin Screening Assays App 20080003240 - Fernandez-Salas; Ester ;   et al. | 2008-01-03 |
Neurotoxins With Enhanced Target Specificity App 20070292920 - Lin; Wei-Jen ;   et al. | 2007-12-20 |
Assays of Molecular or Subcellular Interactivity Using Depolarization After Resonance Transfer Energy (DARET) App 20070275477 - Gilmore; Marcella A. ;   et al. | 2007-11-29 |
Method for treating phantom pain by peripheral administration of a neurotoxin Grant 7,291,344 - Aoki , et al. November 6, 2 | 2007-11-06 |
Method for treating pain by peripheral administration of a neuroptoxin Grant 7,288,260 - Aoki , et al. October 30, 2 | 2007-10-30 |
Luminescence Resonance Energy Transfer (lret) Assays For Clostridial Toxin Activity App 20070243565 - Williams; Dudley J. ;   et al. | 2007-10-18 |
Methods and compositions for the treatment of pancreatitis Grant 7,276,473 - Sachs , et al. October 2, 2 | 2007-10-02 |
Neurotoxins with enhanced target specificity Grant 7,273,722 - Lin , et al. September 25, 2 | 2007-09-25 |
Cell-based Fluorescence Resonance Energy Transfer (fret) Assays For Clostridial Toxins App 20070122858 - Fernandez-Salas; Ester ;   et al. | 2007-05-31 |
Burn pain treatment by peripheral administration of a neurotoxin Grant 7,211,262 - Aoki , et al. May 1, 2 | 2007-05-01 |
Fret protease assays for botulinum serotype A/E toxins Grant 7,208,285 - Steward , et al. April 24, 2 | 2007-04-24 |
Methods for treating pain and hyperhidrosis App 20070048335 - Gil; Daniel W. ;   et al. | 2007-03-01 |
Cell-based fluorescence resonance energy transfer (FRET) assays for clostridial toxins Grant 7,183,066 - Fernandez-Salas , et al. February 27, 2 | 2007-02-27 |
Rescue agents for treating botulinum toxin intoxications Grant 7,172,764 - Li , et al. February 6, 2 | 2007-02-06 |
Post-operative pain treatment by peripheral administration of a neurotoxin Grant 7,172,763 - Aoki , et al. February 6, 2 | 2007-02-06 |
Method for treating a trigeminal neuralgia by peripheral administration of a neurotoxin App 20070014816 - Aoki; Kei Roger ;   et al. | 2007-01-18 |
Method for treating hyperalgesia by peripheral administation of a neurotoxin App 20060275326 - Aoki; Kei Roger ;   et al. | 2006-12-07 |
Method for treating allodynia by peripheral administration of a neurotoxin App 20060275325 - Aoki; Kei Roger ;   et al. | 2006-12-07 |
Methods of modulating intracellular degradation rates of toxins App 20060257430 - Li; Shengwen ;   et al. | 2006-11-16 |
Multivalent clostridial toxin derivatives and methods of their use App 20060211619 - Steward; Lance E. ;   et al. | 2006-09-21 |
Therapy for injured muscles Grant 7,108,857 - Brooks , et al. September 19, 2 | 2006-09-19 |
Method for treating post herpetic neuralgia by peripheral administration of a neurotoxin Grant 7,067,137 - Aoki , et al. June 27, 2 | 2006-06-27 |
Lanthanide-based substrates and methods for determining clostridial toxin activity App 20060063221 - Williams; Dudley J. ;   et al. | 2006-03-23 |
Fluorescence polarization assays for determining clostridial toxin activity App 20060063222 - Williams; Dudley J. ;   et al. | 2006-03-23 |
Method for treating complex regional pain by peripheral administration of a neurotoxin App 20060039916 - Aoki; Kei Roger ;   et al. | 2006-02-23 |
Method for treating phantom pain by peripheral administration of a neurotoxin App 20060039917 - Aoki; Kei Roger ;   et al. | 2006-02-23 |
Novel methods for production of di-chain botulinum toxin App 20060024794 - Li; Shengwen ;   et al. | 2006-02-02 |
Toxin compounds with enhanced membrane translocation characteristics App 20060024331 - Fernandez-Salas; Ester ;   et al. | 2006-02-02 |
Methods of modulating intracellular degradation rates of toxins Grant 6,991,789 - Li , et al. January 31, 2 | 2006-01-31 |
Method for treating a mucus secretion Grant 6,986,893 - Aoki , et al. January 17, 2 | 2006-01-17 |
Methods Of Modulating Intracellular Degradation Rates Of Toxins App 20050287175 - Li, Shengwen ;   et al. | 2005-12-29 |
Therapy for injured muscles App 20050281846 - Brooks, Gregory F. ;   et al. | 2005-12-22 |
Leucine-based motif and Clostridial neurotoxins App 20050276820 - Steward, Lance E. ;   et al. | 2005-12-15 |
Leucine-based motifs and enhanced biological persistence of clostridial neurotoxins App 20050260230 - Steward, Lance E. ;   et al. | 2005-11-24 |
Novel DNA sequences of the botulinum neurotoxin complex of Clostridium botulinum type A-Hall (Allergan) strain for production of therapeutics App 20050169942 - Li, Shengwen ;   et al. | 2005-08-04 |
Method for treating pain by peripheral administration of a neurotoxin App 20050152925 - Aoki, Kei Roger ;   et al. | 2005-07-14 |
Lipid rafts and clostridial toxins App 20050129677 - Li, Shengwen ;   et al. | 2005-06-16 |
Leucine-based motif and clostridial neurotoxins Grant 6,903,187 - Steward , et al. June 7, 2 | 2005-06-07 |
Rescue agents for treating botulinum toxin intoxications App 20050106182 - Li, Shengwen ;   et al. | 2005-05-19 |
Methods and compositions for the treatment of pancreatitis App 20050095251 - Steward, Lance E. ;   et al. | 2005-05-05 |
Pain treatment by peripheral administration of a neurotoxin Grant 6,869,610 - Aoki , et al. March 22, 2 | 2005-03-22 |
Method for treating pain by peripheral administration of a neuroptoxin App 20050058666 - Aoki, Kei Roger ;   et al. | 2005-03-17 |
Methods and compositions for the treatment of pancreatitis Grant 6,843,998 - Steward , et al. January 18, 2 | 2005-01-18 |
Compositions and methods for modulating neural sprouting App 20040228881 - Oliver, Dolly J. ;   et al. | 2004-11-18 |
Clostridial neurotoxin compositions and modified clostridial neurotoxins App 20040220386 - Steward, Lance E. ;   et al. | 2004-11-04 |
Methods of identifying compounds that alter toxin persistence and/or protease activity App 20040219619 - Fernandez-Salas, Ester ;   et al. | 2004-11-04 |
Methods and compositions for the treatment of pancreatitis App 20040176299 - Sachs, George ;   et al. | 2004-09-09 |
Methods and compositions for the treatment of pancreatitis Grant 6,776,990 - Sachs , et al. August 17, 2 | 2004-08-17 |
Botulinum toxin treatment for blepharospasm App 20040151740 - Aoki, Kei Roger ;   et al. | 2004-08-05 |
Use of the neurotoxic component of a botulinum toxin for treating various disorders and conditions and associated pain App 20040126397 - Aoki, Kei Roger ;   et al. | 2004-07-01 |
Botulinum toxin treatment for strabismus App 20040126396 - Aoki, Kei Roger ;   et al. | 2004-07-01 |
Evolved clostridial toxins with altered protease specificity App 20040115727 - Steward, Lance E. ;   et al. | 2004-06-17 |
Cell-based fluorescence resonance energy transfer (FRET) assays for clostridial toxins App 20040072270 - Fernandez-Salas, Ester ;   et al. | 2004-04-15 |
Botulinum toxin therapy for lower back pain App 20040037852 - Aoki, Kei Roger ;   et al. | 2004-02-26 |
Neuralgia pain treatment by peripheral administration of a neurotoxin App 20040028706 - Aoki, Kei Roger ;   et al. | 2004-02-12 |
Pain treatment by peripheral administration of a neurotoxin App 20040018213 - Aoki, Kei Roger ;   et al. | 2004-01-29 |
Burn pain treatment by peripheral administration of a neurotoxin App 20040018214 - Aoki, Kei Roger ;   et al. | 2004-01-29 |
Joint pain treatment by peripheral administration of a neurotoxin App 20040018212 - Aoki, Kei Roger ;   et al. | 2004-01-29 |
Botulinum toxin treatment for cervical dystonia App 20040014663 - Aoki, Kei Roger ;   et al. | 2004-01-22 |
Clostridial neurotoxin compositions and modified clostridial neurotoxins App 20030219462 - Steward, Lance E. ;   et al. | 2003-11-27 |
Method for treating a non-rhinorrhea cholinergic influenced secretion App 20030157134 - Aoki, Kei Roger ;   et al. | 2003-08-21 |
Fret protease assays for clostridial toxins App 20030143651 - Steward, Lance E. ;   et al. | 2003-07-31 |
Fret protease assays for botulinum serotype A/E toxins App 20030143650 - Steward, Lance E. ;   et al. | 2003-07-31 |
Leucine-based motif and clostridial neurotoxins App 20030027752 - Steward, Lance E. ;   et al. | 2003-02-06 |
Pain treatment by peripheral administration of a neurotoxin App 20020176872 - Aoki, Kei Roger ;   et al. | 2002-11-28 |
Neurotoxins with enhanced target specificity App 20020137886 - Lin, Wei-Jen ;   et al. | 2002-09-26 |
Modified clostridial neurotoxins with altered biological persistence App 20020127247 - Steward, Lance E. ;   et al. | 2002-09-12 |
Method for treating a mucus secretion App 20020082197 - Aoki, Kei Roger ;   et al. | 2002-06-27 |
Intraspinal botulinum toxin for treating pain Grant 6,372,226 - Aoki , et al. April 16, 2 | 2002-04-16 |
Methods And Compositions For The Treatment Of Pancreatitis App 20010018049 - SACHS, GEORGE ;   et al. | 2001-08-30 |
Intraspinal botulinum toxin for treating pain App 20010012828 - Aoki, Kei Roger ;   et al. | 2001-08-09 |
Intraspinal methods for treating pain Grant 6,235,289 - Aoki , et al. May 22, 2 | 2001-05-22 |
Modification of clostridial toxins for use as transport proteins Grant 6,203,794 - Dolly , et al. March 20, 2 | 2001-03-20 |
Methods for treating pain Grant 6,113,915 - Aoki , et al. September 5, 2 | 2000-09-05 |
Botulinum toxin antibody detection assay Grant 5,731,161 - Aoki , et al. March 24, 1 | 1998-03-24 |
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