U.S. patent number 3,817,254 [Application Number 05/251,280] was granted by the patent office on 1974-06-18 for transcutaneous stimulator and stimulation method.
This patent grant is currently assigned to Medtronic, Inc.. Invention is credited to Donald D. Maurer.
United States Patent |
3,817,254 |
Maurer |
June 18, 1974 |
TRANSCUTANEOUS STIMULATOR AND STIMULATION METHOD
Abstract
A transcutaneous stimulator for stimulating portions of the
body. The output of the stimulator is a stimulating pulse having
frequency components falling within predetermined frequency band
limits so as to optimally excite touch nerve fibres relative to
nociceptor or pain receptor nerve fibres.
Inventors: |
Maurer; Donald D. (Anoka,
MN) |
Assignee: |
Medtronic, Inc. (Minneapolis,
MN)
|
Family
ID: |
22951251 |
Appl.
No.: |
05/251,280 |
Filed: |
May 8, 1972 |
Current U.S.
Class: |
607/46 |
Current CPC
Class: |
A61N
1/36021 (20130101) |
Current International
Class: |
A61N
1/32 (20060101); A61N 1/34 (20060101); A61N
1/36 (20060101); A61n 001/36 () |
Field of
Search: |
;128/1C,2.1R,419C,419E,419R,420,421,422,423 |
References Cited
[Referenced By]
U.S. Patent Documents
Foreign Patent Documents
Primary Examiner: Kamm; William E.
Attorney, Agent or Firm: Schwartz; Lew Sivertson; Wayne
A.
Claims
I claim:
1. A stimulator adapted for use as a transcutaneous stimulator for
the purpose of organic pain suppression which comprises:
pulse generator means;
filter means for transforming the pulses of the pulse generator
means into output pulses each comprising a plurality of frequency
components having substantially 90 percent of their energy
throughout substantially 100-5,000 Hz; and
output means connected to said filter means for applying said
transformed pulses transcutaneously.
2. The stimulator of claim 1 wherein the transformed pulses are
full cycle pulses.
3. The stimulator of claim 1 wherein the transformed pulses are
half cycle pulses.
4. The stimulator of claim 1 wherein said output means further
comprises constant current means for regulating the current output
of said filter means.
5. A transcutaneous stimulator which comprises:
means for producing a series of pulses, each of said pulses having
frequency components substantially 90 percent of the energy of
which falls within substantially 100-5,000 Hz and
output means connected to said pulse series producing means.
6. The transcutaneous stimulator of claim 5 wherein the pulses are
full cycle pulses.
7. The transcutaneous stimulator of claim 5 wherein the pulses are
half cycle pulses.
8. A method of transcutaneous stimulation which comprises the steps
of:
producing a series of pulses, each of said pulses comprising a
plurality of frequency components having substantially 90 percent
of their energy throughout substantially 100-5,000 Hz; and
applying the pulses to the portion of the body.
Description
BACKGROUND OF THE INVENTION
Peripheral nerve fibres have been classified in order of decreasing
size and conduction velocity in a manner which is now standardized.
Generally, as the fibre size decreases, the amplitude of electrical
stimulation required to elicit an action potential increases. Also,
the smaller fibre will require longer pulse durations than large
fibre stimuli. These differences in nerve response have been used
to selectively stimulate different types of nerve fibres by varying
the amplitude, pulse duration, or pulse repetition rate of an
electrical stimulating pulse. The desired degree of nerve fibre
selectivity, however, has not been achieved in the prior art, with
the result that, for example, an elicited touch response resulting
from the stimulating pulse is often accompanied by a prickly,
stinging, burning, sharp or other unpleasant noxious response.
SUMMARY OF THE INVENTION
The present invention provides a stimulating pulse having frequency
components falling within predetermined frequency band limits. This
pulse reliably elicits a touch response without the heretofore
attendant noxious sensation mentioned above.
It has been demonstrated that the differential excitation of the
touch fibres relative to pain specific fibres inhibits the
transmission of pain to the conscious centers. The type of
stimulation specified herein, optimizes the differential excitation
between touch and pain specific fibres, thus optimizing the
inhibition of pain transmission.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a block diagram of a transcutaneous stimulator embodying
the present invention.
FIG. 2 is a graph of touch and pain response versus frequency.
DETAILED DESCRIPTION OF A PREFERRED EMBODIMENT
There is an increasing interest in external electrical skin
stimulation for such purposes as pain suppression, neuro-muscular
stimulation, communication systems, etcetera. The preferred
embodiment of the present invention as described herein, is
directed particularly at a transcutaneous stimulator for the
suppression of organic pain, although it has obvious applications
beyond this particular field. In understanding the present
invention, the prior art devices shown in U.S. Patent Nos.
1,059,090 and No. 1,305,725 should be mentioned. These devices, are
essentially pulse generators which have the capacity to suppress
organic pain when applied to the body in proper relation to the
nervous system. Along with the organic pain suppression, however,
there is a concurrent noxious sensation produced by the stimulation
which, over a period of time, may become more distracting that the
organic pain being suppressed. Prior art attempts to eliminate this
noxious sensation have included variations in the pulse amplitude,
pulse duration, and pulse repetition rate. To an extent, these
approaches have provided some success but, in their success, have
limited the application of the technique by placing very
restrictive parameters on its operation.
The present invention can best be understood by viewing the pulses
used in the prior art devices in terms of a Fourier transform
analysis. Any pulse has a fundamental sine wave component. Non-sine
wave pulses, in addition, have sine wave components having
frequencies which are multiples of the fundamental frequency. By
determining which of these frequency components operate on which of
the various nerve classifications, it is possible to generate a
signal whose frequency components fall within predetermined
frequency band limits, thus reducing the undesired noxious
sensation. Peripheral nerve fibres have a standard classification
in order of decreasing size and conduction velocity. Those of
particular interest here are the class A-beta fibres which subserve
touch and the class C fibres which are specific for pain. In
addition, it has been demonstrated that the differential excitation
of the A-beta fibres with respect to the C fibres will inhibit the
transmission of pain information from the class C fibres.
With this background, we turn now to FIG. 1 which shows a block
diagram of a stimulator employing the principles of the present
invention. There is shown at 10 a pulse generator which may or may
not be similar to that of the prior art devices. That is, the
output of the pulse generator 10 may be either a full wave or half
wave pulse. The pulse generator 10 is provided with a pulse rate
control 11 which operates in a known manner. The output of the
pulse generator 10 is transmitted by line 12 to a low pass active
filter which may be one of a number of known types. Dependent upon
the output of the pulse generator 10, the low pass filter 13 will
produce a full or half wave pulse of a single frequency or having a
plurality of frequency components within the bonds to be described
hereinafter. The filtered wave is passed from the filter 13 over
the line 14 to a power amplifier and current control 15 whose
output is coupled to the output electrodes 17 and 18 by a
conventional transformer 20. Either or both of the electrodes which
are directly attached to the body may be of a type disclosed in my
copending application, Ser. No. 251,179 filed May 8, 1972, for
Electrode for Transcutaneous Stimulator. A feedback line 21 is
employed to introduce a constant current feature to the stimulator
of the present invention. In addition, in some applications it may
prove necessary to vary the pulse repetition rate to overcome nerve
adaption. This can be accomplished by providing a ramp generator as
an input to the pulse generator 10 in any known manner.
Referring now to FIG. 2, there is shown a plot of touch and pain
response versus frequency. The touch response curve 23 is
essentially a bell shaped curve which results from direct
electrical stimulation. Curve 24 shows the pain response curve with
segments A, B and C. Segments A and C result from secondary effects
of the stimulation, such as, for example, chemical effects Segment
B results from both the secondary effects and the effect of direct
electrical stimulation. A greater differential excitation of touch
nerve fibres over pain nerve fibres will inhibit the transmission
of a pain signal from the pain fibres. Any specific frequency of
stimulation which elicits a greater touch response than pain
response will inhibit the pain transmission thereby eliminating any
noxious sensation from the stimulation. An example of such a
frequency is indicated in FIG. 2 at X.
Similarly, any pulse having individual frequency components which
collectively elicit a greater touch response than pain response
will inhibit pain transmission and eliminate any noxious sensation
from the stimulation.
I have discovered that a substantially pure sine wave pulse, either
full or half wave, within the range of substantially 1,000-3,000 Hz
produces a greater touch response than pain response thereby
eliminating any noxious sensation. Similarly, a stimulation pulse
having a plurality of frequency components and substantially 90
percent of its energy falling within the predetermined frequency
band limits of substantially 100-5,000 Hz with the fundamental
frequency preferably within the range of substantially 1,000-3,000
Hz will produce a greater touch response than pain response thereby
eliminating any noxious sensations.
Obviously, many modifications and variations of the present
invention are possible in light of the above teaching.
Specifically, there are many alternative ways of generating the
optimized waveforms disclosed herein which do not depart from the
intended scope of the application. For example, a frequency
synthesizer could be employed in place of the pulse generator 10
and filter 13. Accordingly, it is to be understood that, within the
scope of the appended claims, the invention may be practiced
otherwise than as specifically described.
* * * * *