loadpatents
name:-0.086663961410522
name:-0.077182054519653
name:-0.02226996421814
Valenzuela; David M. Patent Filings

Valenzuela; David M.

Patent Applications and Registrations

Patent applications and USPTO patent grants for Valenzuela; David M..The latest application filed is for "targeted modification of rat genome".

Company Profile
22.80.85
  • Valenzuela; David M. - Yorktown Heights NY
  • Valenzuela, David M. - Franklin Square NY
*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.
Patent Activity
PatentDate
Targeted Modification Of Rat Genome
App 20210301301 - Lee; Jeffrey D. ;   et al.
2021-09-30
Genetic Modification Of Rats
App 20210130846 - Lee; Jeffrey D. ;   et al.
2021-05-06
Methods of modifying genes in eukaryotic cells
Grant 10,988,776 - Economides , et al. April 27, 2
2021-04-27
Targeted modification of rat genome
Grant 10,975,390 - Lee , et al. April 13, 2
2021-04-13
Genetic modification of rats
Grant 10,894,965 - Lee , et al. January 19, 2
2021-01-19
Non-human Animals Having A Hexanucleotide Repeat Expansion In A C9orf72 Locus
App 20200370054 - Heslin; David ;   et al.
2020-11-26
Non-human animals having a hexanucleotide repeat expansion in a C9ORF72 locus
Grant 10,781,453 - Heslin , et al. Sept
2020-09-22
Methods And Compositions For The Targeted Modification Of A Genome
App 20200291425 - Frendewey; David ;   et al.
2020-09-17
Methods and compositions for the targeted modification of a mouse ES cell genome
Grant 10,711,280 - Frendewey , et al.
2020-07-14
Nuclease-mediated Dna Assembly
App 20200208161 - Schoenherr; Chris ;   et al.
2020-07-02
Mice that produce hybrid antibodies
Grant 10,640,800 - Murphy , et al.
2020-05-05
Nuclease-mediated DNA assembly
Grant 10,626,402 - Schoenherr , et al.
2020-04-21
Mice that produce hybrid antibodies
Grant 10,584,364 - Murphy , et al.
2020-03-10
Genetically modified mice that produce hybrid antibodies
Grant 10,526,630 - Murphy , et al. J
2020-01-07
Methods And Compositions For Targeted Genetic Modification Using Paired Guide Rnas
App 20200002730 - Frendewey; David ;   et al.
2020-01-02
Methods And Compositions For Targeted Genetic Modification Using Paired Guide Rnas
App 20200002731 - Frendewey; David ;   et al.
2020-01-02
Methods And Compositions For Generating Or Maintaining Pluripotent Cells
App 20190382730 - Kuno; Junko ;   et al.
2019-12-19
Methods and compositions for targeted genetic modification using paired guide RNAs
Grant 10,457,960 - Frendewey , et al. Oc
2019-10-29
Targeted Modification Of Rat Genome
App 20190323032 - Lee; Jeffrey D. ;   et al.
2019-10-24
Genetic Modification Of Rats
App 20190316149 - Lee; Jeffrey D. ;   et al.
2019-10-17
Methods and compositions for generating or maintaining pluripotent cells
Grant 10,428,310 - Kuno , et al. October 1, 2
2019-10-01
Targeted modification of rat genome
Grant 10,385,359 - Lee , et al. A
2019-08-20
Mouse embryonic stem cells comprising a hybrid heavy chain immunoglobulin locus
Grant 10,378,039 - Murphy , et al. A
2019-08-13
Mice that produce hybrid antibodies
Grant 10,378,038 - Murphy , et al. A
2019-08-13
Methods of making a nucleic acid encoding a human variable region
Grant 10,378,037 - Murphy , et al. A
2019-08-13
Mice that produce hybrid antibodies
Grant 10,378,040 - Murphy , et al. A
2019-08-13
Methods And Compositions For Modifying A Targeted Locus
App 20190225992 - Auerbach; Wojtek ;   et al.
2019-07-25
Non-human Animals Having A Disruption In A C9orf72 Locus
App 20190216062 - Atanasio; Amanda ;   et al.
2019-07-18
Compositions and methods for modifying cells
Grant 10,344,299 - Economides , et al. July 9, 2
2019-07-09
Nuclease-mediated Dna Assembly
App 20190194668 - Schoenherr; Chris ;   et al.
2019-06-27
Genetic modification of rats
Grant 10,329,582 - Lee , et al.
2019-06-25
Nuclease-mediated targeting with large targeting vectors
Grant 10,301,646 - Frendewey , et al.
2019-05-28
Methods and compositions for modifying a targeted locus
Grant 10,294,494 - Auerbach , et al.
2019-05-21
Non-human animals having a disruption in a C9ORF72 locus
Grant 10,285,388 - Atanasio , et al.
2019-05-14
Stem Cells For Modeling Type 2 Diabetes
App 20190136201 - Gong; Guochun ;   et al.
2019-05-09
Nuclease-mediated DNA assembly
Grant 10,273,488 - Schoenherr , et al.
2019-04-30
Methods And Compositions For The Targeted Modification Of A Genome
App 20190112619 - Frendewey; David ;   et al.
2019-04-18
Methods of modifying eukaryotic cells
Grant 10,227,625 - Murphy , et al.
2019-03-12
Methods and compositions for the targeted modification of a mouse embryonic stem cell genome
Grant 10,208,317 - Frendewey , et al. Feb
2019-02-19
Stem cells for modeling type 2 diabetes
Grant 10,196,613 - Gong , et al. Fe
2019-02-05
Methods Of Modifying Genes In Eukaryotic Cells
App 20180371493 - Economides; Aris N. ;   et al.
2018-12-27
Methods and compositions for modifying a targeted locus
Grant 10,106,820 - Auerbach , et al. October 23, 2
2018-10-23
Methods And Compositions For Targeted Genetic Modifications And Methods Of Use
App 20180251784 - Frendewey; David ;   et al.
2018-09-06
Methods and compositions for generating a mouse
Grant 10,039,269 - Poueymirou , et al. August 7, 2
2018-08-07
Non-human Animals Having A Hexanucleotide Repeat Expansion In A C9orf72 Locus
App 20180094267 - Heslin; David ;   et al.
2018-04-05
Methods for producing a mouse XY embryonic (ES) cell line capable of producing a fertile XY female mouse in an F0 generation
Grant 9,902,971 - Frendewey , et al. February 27, 2
2018-02-27
Nuclease-Mediated Targeting With Large Targeting Vectors
App 20180037910 - Frendewey; David ;   et al.
2018-02-08
Nuclease-mediated Dna Assembly
App 20180002708 - Schoenherr; Chris ;   et al.
2018-01-04
Nuclease-mediated targeting with large targeting vectors
Grant 9,834,786 - Frendewey , et al. December 5, 2
2017-12-05
Methods And Compositions For Generating A Mouse
App 20170295762 - Poueymirou; William ;   et al.
2017-10-19
Compositions and Methods for Modifying Cells
App 20170260544 - Economides; Aris N. ;   et al.
2017-09-14
miRNA-regulated differentiation-dependent self-deleting cassette
Grant 9,745,598 - Frendewey , et al. August 29, 2
2017-08-29
Nuclease-mediated DNA assembly
Grant 9,738,897 - Schoenherr , et al. August 22, 2
2017-08-22
Methods and compositions for generating a mouse
Grant 9,730,434 - Poueymirou , et al. August 15, 2
2017-08-15
Methods And Compositions For Modifying A Targeted Locus
App 20170211099 - Auerbach; Wojtek ;   et al.
2017-07-27
Targeted Modification Of Rat Genome
App 20170204430 - Lee; Jeffrey D. ;   et al.
2017-07-20
Methods of making a nucleic acid encoding a human variable region
Grant 9,708,635 - Murphy , et al. July 18, 2
2017-07-18
Method for detecting the replacement of an endogenous allele with a modified allele by homologous recombination in a mouse ES cell
Grant 9,677,129 - Economides , et al. June 13, 2
2017-06-13
Promoter-regulated differentiation-dependent self-deleting cassette
Grant 9,677,086 - Frendewey , et al. June 13, 2
2017-06-13
Lincrna-deficient Non-human Animals
App 20170071173 - Lai; Ka-Man Venus ;   et al.
2017-03-16
Methods And Compositions For The Targeted Modification Of A Genome
App 20170067078 - Frendewey; David ;   et al.
2017-03-09
Nuclease-mediated DNA assembly
Grant 9,580,715 - Schoenherr , et al. February 28, 2
2017-02-28
Genetic Modification Of Rats
App 20170037429 - Lee; Jeffrey D. ;   et al.
2017-02-09
IncRNA-knockout mice
Grant 9,554,564 - Lai , et al. January 31, 2
2017-01-31
Methods and compositions for the targeted modification of a mouse genome
Grant 9,546,384 - Frendewey , et al. January 17, 2
2017-01-17
Methods of modifying eukaryotic cells
Grant 9,528,136 - Murphy , et al. December 27, 2
2016-12-27
Non-human Animals Having A Disruption In A C9orf72 Locus
App 20160345547 - Atanasio; Amanda ;   et al.
2016-12-01
ES Cell-Derived Mice From Diploid Host Embryo Injection
App 20160316728 - Poueymirou; William ;   et al.
2016-11-03
Mice That Produce Hybrid Antibodies
App 20160316731 - Murphy; Andrew J. ;   et al.
2016-11-03
Methods And Compositions For Generating A Mouse
App 20160316729 - Poueymirou; William ;   et al.
2016-11-03
Promoter-regulated Differentiation-dependent Self-deleting Cassette
App 20160304903 - Frendewey; David ;   et al.
2016-10-20
Methods and compositions for generating a mouse
Grant 9,414,575 - Poueymirou , et al. August 16, 2
2016-08-16
Promoter-regulated differentiation-dependent self-deleting cassette
Grant 9,410,163 - Frendewey , et al. August 9, 2
2016-08-09
Methods of producing hybrid antibodies
Grant 9,388,446 - Murphy , et al. July 12, 2
2016-07-12
Methods of producing hybrid antibodies
Grant 9,382,567 - Murphy , et al. July 5, 2
2016-07-05
Methods of producing hybrid antibodies
Grant 9,376,699 - Murphy , et al. June 28, 2
2016-06-28
Stem Cells For Modeling Type 2 Diabetes
App 20160177273 - Gong; Guochun ;   et al.
2016-06-23
Genetically modified mice that produce hybrid antibodies
Grant 9,371,553 - Murphy , et al. June 21, 2
2016-06-21
miRNA-REGULATED DIFFERENTIATION-DEPENDENT SELF-DELETING CASSETTE
App 20160150767 - Frendewey; David ;   et al.
2016-06-02
Methods of producing hybrid antibodies
Grant 9,353,394 - Murphy , et al. May 31, 2
2016-05-31
Methods And Compositions For Targeted Genetic Modification Using Paired Guide Rnas
App 20160145646 - Frendewey; David ;   et al.
2016-05-26
Nuclease-mediated Dna Assembly
App 20160115486 - Schoenherr; Chris ;   et al.
2016-04-28
Methods And Compositions For Generating Or Maintaining Pluripotent Cells
App 20160108369 - Kuno; Junko ;   et al.
2016-04-21
Genetic Modification Of Rats
App 20160108360 - Lee; Jeffrey D. ;   et al.
2016-04-21
Methods And Compositions For The Targeted Modification Of A Genome
App 20160060657 - Frendewey; David ;   et al.
2016-03-03
MiRNA-regulated differentiation-dependent self-deleting cassette
Grant 9,267,152 - Frendewey , et al. February 23, 2
2016-02-23
Methods And Compositions For Targeted Genetic Modifications And Methods Of Use
App 20160046960 - Frendewey; David ;   et al.
2016-02-18
Methods and compositions for the targeted modification of a genome
Grant 9,228,208 - Frendewey , et al. January 5, 2
2016-01-05
Methods And Compositions For Modifying A Targeted Locus
App 20150376650 - Auerbach; Wojtek ;   et al.
2015-12-31
Methods And Compositions For Targeted Genetic Modifications And Methods Of Use
App 20150376651 - Frendewey; David ;   et al.
2015-12-31
Nuclease-mediated Dna Assembly
App 20150376628 - Schoenherr; Chris ;   et al.
2015-12-31
miRNA-REGULATED DIFFERENTIATION-DEPENDENT SELF-DELETING CASSETTE
App 20150291978 - Frendewey; David ;   et al.
2015-10-15
miRNA-regulated differentiation-dependent self-deleting cassette
Grant 9,096,870 - Frendewey , et al. August 4, 2
2015-08-04
Methods and Compositions for the Targeted Modification of a Genome
App 20150159174 - Frendewey; David ;   et al.
2015-06-11
Methods And Compositions For The Targeted Modification Of A Genome
App 20150159175 - Frendewey; David ;   et al.
2015-06-11
Promoter-regulated Differentiation-dependent Self-deleting Cassette
App 20150099296 - Frendewey; David ;   et al.
2015-04-09
lincRNA-DEFICIENT NON-HUMAN ANIMALS
App 20150047062 - Lai; Ka-Man Venus ;   et al.
2015-02-12
Promoter-regulated differentiation-dependent self-deleting cassette
Grant 8,946,504 - Frendewey , et al. February 3, 2
2015-02-03
Promoter-regulated differentiation-dependent self-deleting cassette
Grant 8,946,505 - Frendewey , et al. February 3, 2
2015-02-03
Methods And Compositions For Generating A Mouse
App 20140331340 - Poueymirou; William ;   et al.
2014-11-06
Targeted Modification Of Rat Genome
App 20140309487 - Lee; Jeffrey D. ;   et al.
2014-10-16
Targeted Modification Of Rat Genome
App 20140310828 - Lee; Jeffrey D. ;   et al.
2014-10-16
Method for genetically modifying isolated non-human mammalian cell by homologous recombination
Grant 8,846,402 - Economides , et al. September 30, 2
2014-09-30
Conditioned culture media
Grant 8,816,150 - Poueymirou , et al. August 26, 2
2014-08-26
Genetic Modification Of Rats
App 20140235933 - Lee; Jeffrey D. ;   et al.
2014-08-21
Cloned Non-human Animals Free Of Selective Markers
App 20140221734 - Gong; Guochun ;   et al.
2014-08-07
Hybrid antibodies comprising human variable regions and mouse constant regions produced in a genetically modified mouse
Grant 8,791,323 - Murphy , et al. July 29, 2
2014-07-29
Promoter-regulated Differentiation-dependent Self-deleting Cassette
App 20140199761 - Frendewey; David ;   et al.
2014-07-17
miRNA-REGULATED DIFFERENTIATION-DEPENDENT SELF-DELETING CASSETTE
App 20140189900 - Frendewey; David ;   et al.
2014-07-03
Compositions and Methods for Modifying Cells
App 20140178879 - ECONOMIDES; ARIS N. ;   et al.
2014-06-26
Method for genetically modifying mouse embryonic stem cell by homologous recombination
Grant 8,759,105 - Economides , et al. June 24, 2
2014-06-24
Methods Of Modifying Genes In Eukaryotic Cells
App 20140155689 - Economides; Aris N. ;   et al.
2014-06-05
MiRNA-regulated differentiation-dependent self-deleting cassette
Grant 8,697,851 - Frendewey , et al. April 15, 2
2014-04-15
Parental Cell Lines for Making Cassette-Free F1 Progeny
App 20140075586 - Gong; Guochun ;   et al.
2014-03-13
Nuclease-Mediated Targeting With Large Targeting Vectors
App 20130309670 - Frendewey; David ;   et al.
2013-11-21
Promoter-regulated Differentiation-dependent Self-deleting Cassette
App 20130312128 - FRENDEWEY; David ;   et al.
2013-11-21
Promoter-regulated Differentiation-dependent Self-deleting Cassette
App 20130312129 - FRENDEWEY; David ;   et al.
2013-11-21
Promoter-regulated differentiation-dependent self-deleting cassette
Grant 8,518,392 - Frendewey , et al. August 27, 2
2013-08-27
Methods of Modifying Eukaryotic Cells
App 20130137101 - Economides; Aris N. ;   et al.
2013-05-30
miRNA-Regulated Differentiation-Dependent Self-Deleting Cassette
App 20130095565 - FRENDEWEY; David ;   et al.
2013-04-18
miRNA-regulated differentiation-dependent self-deleting cassette
Grant 8,354,389 - Frendewey , et al. January 15, 2
2013-01-15
miRNA-Regulated Differentiation-Dependent Self-Deleting Cassette
App 20110041196 - FRENDEWEY; David ;   et al.
2011-02-17
Promoter-Regulated Differentiation-Dependent Self-Deleting Cassette
App 20110041197 - FRENDEWEY; DAVID ;   et al.
2011-02-17
Method for making homozygous genetic modifications
Grant 7,659,442 - Poueymirou , et al. February 9, 2
2010-02-09
ES Cell-Derived Mice From Diploid Host Embryo Injection
App 20090271884 - POUEYMIROU; William ;   et al.
2009-10-29
Method for making genetic modifications
Grant 7,576,259 - Poueymirou , et al. August 18, 2
2009-08-18
Methods of modifying eukaryotic cells
App 20090055943 - Economides; Aris N. ;   et al.
2009-02-26
Conditioned culture media
App 20080078000 - Poueymirou; William ;   et al.
2008-03-27
Method for making homozygous genetic modifications
App 20080078001 - Poueymirou; William ;   et al.
2008-03-27
Method for making genetic modifications
App 20080028479 - Poueymirou; William ;   et al.
2008-01-31
Methods of modifying genes in eukaryotic cells
App 20070275466 - Economides; Aris N. ;   et al.
2007-11-29
Method for generating an animal homozygous for a genetic modification
Grant 7,294,754 - Poueymirou , et al. November 13, 2
2007-11-13
Therapeutic method for treating bone formation diseases
Grant 7,285,532 - Economides , et al. October 23, 2
2007-10-23
Morphogenic protein
Grant 7,241,739 - Valenzuela , et al. July 10, 2
2007-07-10
Genome mutation by intron insertion into an embryonic stem cell genome
Grant 7,205,148 - Economides , et al. April 17, 2
2007-04-17
Method for generating an animal homozygous for a genetic modification
App 20060085866 - Poueymirou; William ;   et al.
2006-04-20
Methods for identifying a cell or an embryo carrying a Y chromosome
App 20060064770 - Frendewey; David ;   et al.
2006-03-23
Methods of modifying eukaryotic cells
App 20050144655 - Economides, Aris N. ;   et al.
2005-06-30
Method of improving gene targeting using a ubiquitin promoter
App 20050101017 - Auerbach, Wojtek ;   et al.
2005-05-12
TIE-2 ligand-4
Grant 6,881,395 - Valenzuela , et al. April 19, 2
2005-04-19
Tyrosine kinase receptors and ligands
Grant 6,852,838 - Valenzuela , et al. February 8, 2
2005-02-08
Tie-2 ligand-3
Grant 6,846,914 - Valenzuela , et al. January 25, 2
2005-01-25
Methods of modifying genes in eukaryotic cells
App 20050003543 - Economides, Aris N. ;   et al.
2005-01-06
Therapeutic method for treating bone formation diseases
App 20040132661 - Economides, Aris N. ;   et al.
2004-07-08
Novel morphogenic protein
App 20030199042 - Valenzuela, David M. ;   et al.
2003-10-23
Morphogenic proteins
Grant 6,610,510 - Valenzuela , et al. August 26, 2
2003-08-26
Methods of modifying eukaryotic cells
Grant 6,586,251 - Economides , et al. July 1, 2
2003-07-01
Novel ligands, methods of making and uses thereof
App 20030064470 - Valenzuela, David M. ;   et al.
2003-04-03
Novel ligands, methods of making and uses thereof
App 20030059887 - Valenzuela, David M. ;   et al.
2003-03-27
Novel tyrosine kinase receptors and ligands
App 20020164702 - Valenzuela, David M. ;   et al.
2002-11-07
Novel orphan receptors
App 20020160451 - Masiakowski, Piotr J. ;   et al.
2002-10-31
Methods of modifying eukaryotic cells
App 20020106628 - Economides, Aris N. ;   et al.
2002-08-08
Dorsal tissue affecting factor and compositions
App 20020102643 - Valenzuela, David M. ;   et al.
2002-08-01
Tie ligand-3, methods of making and uses thereof
Grant 5,851,797 - Valenzuela , et al. December 22, 1
1998-12-22
Hybridoma cell lines and antibodies that bind noggin
Grant 5,821,124 - Valenzuela , et al. October 13, 1
1998-10-13
Tyrosine kinase receptors and ligands
Grant 5,814,478 - Valenzuela , et al. September 29, 1
1998-09-29
Monoclonal antibodies recognizing parathyroid hormone-like protein
Grant 5,217,896 - Kramer , et al. June 8, 1
1993-06-08

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