| Patent | Date |
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Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissue
Grant 11,351,167 - Laberge , et al. June 7, 2 | 2022-06-07 |
Treatment Of Parkinson's Disease And Other Conditions Caused Or Mediated By Senescent Astrocytes Using Small Molecule Senolytic Agents
App 20220096466 - Chinta; Shankar J. ; et al. | 2022-03-31 |
Methods of Inhibiting Pathological Angiogenesis
App 20220072015 - Tsuruda; Pam ; et al. | 2022-03-10 |
Acyl Sulfonamides that are BCL Family Antagonists for Use in Clinical Management of Conditions Caused or Mediated by Senescent Cells and for Treating Cancer
App 20220017485 - Beausoleil; Anne-Marie ; et al. | 2022-01-20 |
Killing Senescent Cells And Treating Senescence-Associated Conditions Using A Bcl Inhibitor And An Mcl-1 Inhibitor
App 20210379078 - Kwak; Pieter Bas ; et al. | 2021-12-09 |
Methods of inhibiting pathological angiogenesis
Grant 11,129,838 - Tsuruda , et al. September 28, 2 | 2021-09-28 |
Acylsulfonamide derivatives for treating senescence-associated diseases and disorders
Grant 11,111,259 - Backes , et al. September 7, 2 | 2021-09-07 |
Treating Cardiovascular Disease By Selectively Eliminating Senescent Cells
App 20210169875 - Laberge; Remi-Martin ; et al. | 2021-06-10 |
Treating Liver Disease By Selectively Eliminating Senescent Cells
App 20210169876 - Laberge; Remi-Martin ; et al. | 2021-06-10 |
Antibodies Directed To Tie-2 And Methods Of Use
App 20210155697 - Damiano; Jason ; et al. | 2021-05-27 |
Acyl sulfonamides that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer
Grant 10,981,892 - Beausoleil , et al. April 20, 2 | 2021-04-20 |
Phospholidines that are Bcl Family Antagonists for Use in Clinical Management of Conditions Caused or Mediated by Senescent Cells and for Treating Cancer
App 20210070788 - Beausoleil; Anne-Marie ; et al. | 2021-03-11 |
Treating Cognitive Decline And Other Neurodegenerative Conditions By Selectively Removing Senescent Cells From Neurological Tissue
App 20210030752 - Laberge; Remi-Martin ; et al. | 2021-02-04 |
Phosphonamidates that are BCL Family Antagonists for Use in Clinical Management of Conditions Caused or Mediated by Senescent Cells and for Treating Cancer
App 20200399259 - Beausoleil; Anne-Marie ; et al. | 2020-12-24 |
Acyl Sulfonamides that are BCL Family Antagonists for Use in Clinical Management of Conditions Caused or Mediated by Senescent Cells and for Treating Cancer
App 20200392105 - Beausoleil; Anne-Marie ; et al. | 2020-12-17 |
Composition Comprising A Gene Vector That Selectively Depletes P16 Positive Senescent Cells
App 20200370029 - Lichtsteiner; Serge ; et al. | 2020-11-26 |
Inhibitors of HSP90, PI3-Kinase, Proteasome, HDAC, and P97 Pathways for Selective Removal of Senescent Cells in the Treatment of Age Related Conditions
App 20200360386 - Hudson; Ryan ; et al. | 2020-11-19 |
Treatment of Lung Diseases Using Pharmaceutical Agents that Eliminate Senescent Cells
App 20200354336 - Vlahakis; Nick ; et al. | 2020-11-12 |
Use of a Heterocyclic Bcl-xL Inhibitor and Related Analogs for Removing Senescent Cells in the Treatment of Eye Diseases and Other Age-Related Conditions
App 20200338094 - David; Nathaniel ; et al. | 2020-10-29 |
Use Of A Heterocyclic Bcl-2 Inhibitor For Removing Senescent Cells And Treating Senescence-associated Conditions
App 20200338097 - David; Nathaniel ; et al. | 2020-10-29 |
Acyl Sulfonamides that are BCL Family Antagonists for Use in Clinical Management of Conditions Caused or Mediated by Senescent Cells and for Treating Cancer
App 20200317640 - Beausoleil; Anne-Marie ; et al. | 2020-10-08 |
Acylsulfonamide Derivatives For Treating Senescence-associated Diseases And Disorders
App 20200291050 - Backes; Bradley ; et al. | 2020-09-17 |
Conjugates that are configured for targeted delivery of therapeutic compounds to senescent cells
Grant 10,745,445 - Squires A | 2020-08-18 |
Phospholidines that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer
Grant 10,745,429 - Beausoleil , et al. A | 2020-08-18 |
Methods of Inhibiting Pathological Angiogenesis
App 20200253991 - Kind Code | 2020-08-13 |
Phosphonamidates that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer
Grant 10,738,042 - Beausoleil , et al. A | 2020-08-11 |
Acyl sulfonamides that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer
Grant 10,717,722 - Beausoleil , et al. | 2020-07-21 |
Acyl phosphonamidates and acyl benzylamines that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer
Grant 10,703,745 - Beausoleil , et al. | 2020-07-07 |
Treatment of Lung Diseases Using Pharmaceutical Agents that Eliminate Senescent Cells
App 20200199103A1 - | 2020-06-25 |
Peptide-based proteasome inhibitors for treating conditions mediated by senescent cells and for treating cancer
Grant 10,689,416 - Hudson , et al. | 2020-06-23 |
Technology to inhibit vascular changes that lead to vision loss in the eye
Grant 10,588,916 - Tsuruda , et al. | 2020-03-17 |
Chemical Entities That Kill Senescent Cells For Use In Treating Age-related Disease
App 20200069703 - David; Nathaniel | 2020-03-05 |
Composition comprising a gene vector that selectively depletes P16 positive senescent cells
Grant 10,550,378 - Lichtsteiner , et al. Fe | 2020-02-04 |
Treating Cognitive Decline And Other Neurodegenerative Conditions By Selectively Removing Senescent Cells From Neurological Tiss
App 20200030323 - Laberge; Remi-Martin ; et al. | 2020-01-30 |
Peptide-based proteasome inhibitors for treating conditions mediated by senescent cells and for treating cancer
App 20200002378 - Hudson; Ryan ; et al. | 2020-01-02 |
Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitor
Grant 10,517,866 - Laberge , et al. Dec | 2019-12-31 |
Peptide-based proteasome inhibitors for treating conditions mediated by senescent cells and for treating cancer
Grant 10,519,197 - Hudson , et al. Dec | 2019-12-31 |
Acyl Sulfonamides that are BCL Family Antagonists for Use in Clinical Management of Conditions Caused or Mediated by Senescent C
App 20190382371 - Beausoleil; Anne-Marie ; et al. | 2019-12-19 |
Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision loss
Grant 10,478,433 - Laberge , et al. Nov | 2019-11-19 |
Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eye
Grant 10,478,432 - Laberge , et al. Nov | 2019-11-19 |
Therapy For Removing Senescent Cells And Treating Senescence-associated Disease Using An Mdm2 Inhibitor
App 20190343832 - Laberge; Remi-Martin ; et al. | 2019-11-14 |
Composition Comprising A Gene Vector That Selectively Depletes P16 Positive Senescent Cells
App 20190316109 - Lichtsteiner; Serge ; et al. | 2019-10-17 |
Chemical entities that kill senescent cells for use in treating age-related disease
Grant 10,426,788 - David October 1, 2 | 2019-10-01 |
Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinase
Grant 10,413,542 - Laberge , et al. Sept | 2019-09-17 |
Products Of Chiral Synthesis Of Cis-imidazoline Compounds And Their Use
App 20190270726 - von Geldern; Thomas W. ; et al. | 2019-09-05 |
Treatment Of Parkinson's Disease And Other Conditions Caused Or Mediated By Senescent Astrocytes Using Small Molecule Senolytic
App 20190269675 - Chinta; Shankar J. ; et al. | 2019-09-05 |
Peptide-based proteasome inhibitors for treating conditions mediated by senescent cells and for treating cancer
App 20190248837 - Hudson; Ryan ; et al. | 2019-08-15 |
Replication conditional virus that specifically kills senescent cells
Grant 10,378,002 - Lichtsteiner , et al. A | 2019-08-13 |
Passive Vaccine For Elimination Of Senescent Cells
App 20190201510 - Vasserot; Alain Philippe ; et al. | 2019-07-04 |
Chiral synthesis method for producing cis-imidazoline compounds for pharmaceutical use
Grant 10,329,279 - von Geldern , et al. | 2019-06-25 |
Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques
Grant 10,328,058 - Baker , et al. | 2019-06-25 |
Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cells
Grant 10,328,073 - Laberge , et al. | 2019-06-25 |
Chemical Compounds For Treating Atherosclerosis By Stabilizing Atherosclerotic Plaques Or Delaying Atherogenesis
App 20190175623 - Laberge; Remi-Martin ; et al. | 2019-06-13 |
Technology to Inhibit Progression of Neovascularization and Vaso-Obliteration
App 20190151337 - Tsuruda; Pam ; et al. | 2019-05-23 |
Replication Conditional Virus that Specifically Kills Senescent Cells
App 20190136215 - Lichtsteiner; Serge ; et al. | 2019-05-09 |
Immunogenic compositions for inducing an immune response for elimination of senescent cells
Grant 10,279,018 - Vasserot , et al. | 2019-05-07 |
Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimen
Grant 10,258,618 - Laberge , et al. | 2019-04-16 |
Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell population
Grant 10,213,426 - Laberge , et al. Feb | 2019-02-26 |
Chemical entities that kill senescent cells for use in treating age-related disease
Grant 10,195,213 - David Fe | 2019-02-05 |
Use Of Sulfonamide Inhibitors Of Bcl-2 And Bcl-xl To Treat Ophthalmic Disease By Selectively Removing Senescent Cells
App 20190022090 - Laberge; Remi-Martin ; et al. | 2019-01-24 |
Pharmaceutical Products and Drug Combinations for Treating Atherosclerosis by Stabilizing Atherosclerotic Plaques and Promoting Plaque Regression
App 20190000846 - van Deursen; Jan M.A. ; et al. | 2019-01-03 |
Chiral Synthesis Method For Producing Cis-imidazoline Compounds For Pharmaceutical Use
App 20180362510 - von Geldern; Thomas W. ; et al. | 2018-12-20 |
Treatment of joint pain
Grant 10,130,628 - David , et al. November 20, 2 | 2018-11-20 |
Unit Dose of an MDM2 Inhibitor that Provides Long-Lasting Relief from Idiopathic Pulmonary Fibrosis and other Pulmonary Conditions by Selectively Removing Senescent Cells from the Lung
App 20180303828 - Laberge; Remi-Martin ; et al. | 2018-10-25 |
Methods and Compositions for Killing Senescent Cells and for Treating Senescence-Associated Diseases and Disorders
App 20180256568 - Laberge; Remi-Martin ; et al. | 2018-09-13 |
Removing Senescent Cells From A Mixed Cell Population Or Tissue Using A Phosphoinositide 3-kinase (pi3k) Inhibitor
App 20180250296 - Laberge; Remi-Martin ; et al. | 2018-09-06 |
Treatment of Ophthalmic Conditions by Selectively Removing Senescent Cells from the Eye
App 20180235957 - Laberge; Remi-Martin ; et al. | 2018-08-23 |
Treating Pulmonary Conditions By Selectively Removing Senescent Cells From The Lung Using An Intermittent Dosing Regimen
App 20180235956 - Laberge; Remi-Martin ; et al. | 2018-08-23 |
Conjugates That Are Configured For Targeted Delivery Of Therapeutic Compounds To Senescent Cells
App 20180215791 - Squires; Shayne | 2018-08-02 |
Compositions And Methods For Treating Senescence-associated Diseases And Disorders
App 20180193458 - Lopez-Dominguez; Jose Alberto ; et al. | 2018-07-12 |
Chemical Entities That Kill Senescent Cells For Use In Treating Age-related Disease
App 20180193359 - David; Nathaniel | 2018-07-12 |
Treatment of ophthalmic conditions by selectively removing senescent cells from the eye
Grant 10,010,546 - Laberge , et al. July 3, 2 | 2018-07-03 |
Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2
Grant 9,993,472 - Laberge , et al. June 12, 2 | 2018-06-12 |
Chiral synthesis method for producing cis-imidazoline compounds for pharmaceutical use
Grant 9,988,368 - von Geldern , et al. June 5, 2 | 2018-06-05 |
Use of sulfonamide inhibitors of Bcl-2 to treat senescence-associated lung conditions such as pulmonary fibrosis and chronic obstructive pulmonary disease
Grant 9,980,962 - Laberge , et al. May 29, 2 | 2018-05-29 |
Drug conjugates for delivering compounds to senescent cells
Grant 9,969,776 - Squires May 15, 2 | 2018-05-15 |
Treatment Of Ophthalmic Conditions By Selectively Removing Senescent Cells From The Eye
App 20180117038 - Laberge; Remi-Martin ; et al. | 2018-05-03 |
Treatment for Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease
App 20180110787 - Laberge; Remi-Martin ; et al. | 2018-04-26 |
Use of a Heterocyclic Bcl-xL Inhibitor and Related Analogs for Removing Senescent Cells in the Treatment of Eye Diseases and Other Age-Related Conditions
App 20180000816 - David; Nathaniel ; et al. | 2018-01-04 |
Treatment for osteoarthritis by intra-articular administration of a cis-imidazoline
Grant 9,855,266 - Laberge , et al. January 2, 2 | 2018-01-02 |
Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cells
Grant 9,849,128 - Laberge , et al. December 26, 2 | 2017-12-26 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders
App 20170348307 - Laberge; Remi-Martin ; et al. | 2017-12-07 |
Treatment of Pain
App 20170326136 - David; Nathaniel ; et al. | 2017-11-16 |
Compounds And Therapeutic Uses
App 20170281649 - David; Nathaniel | 2017-10-05 |
Use Of A Heterocyclic Bcl-2 Inhibitor For Removing Senescent Cells And Treating Senescence-associated Conditions
App 20170266211 - David; Nathaniel ; et al. | 2017-09-21 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders
App 20170224680 - Laberge; Remi-Martin ; et al. | 2017-08-10 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders
App 20170209435 - Laberge; Remi-Martin ; et al. | 2017-07-27 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders
App 20170196857 - Laberge; Remi-Martin ; et al. | 2017-07-13 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders
App 20170196858 - Laberge; Remi-Martin ; et al. | 2017-07-13 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders
App 20170198253 - Laberge; Remi-Martin ; et al. | 2017-07-13 |
Compositions And Methods For Detecting Or Eliminating Senescent Cells To Diagnose Or Treat Disease
App 20170087252 - Squires; Shayne | 2017-03-30 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders
App 20160339019 - Laberge; Remi-Martin ; et al. | 2016-11-24 |
Compositions And Methods For Detecting Or Eliminating Senescent Cells To Diagnose Or Treat Disease
App 20160166718 - Squires; Shayne | 2016-06-16 |
Compositions And Methods For Detecting Or Eliminating Senescent Cells To Diagnose Or Treat Disease
App 20160017033 - Squires; Shayne | 2016-01-21 |
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