loadpatents
Patent applications and USPTO patent grants for Roche Innovation Center Copenhagen A/S.The latest application filed is for "angptl2 antisense oligonucleotides and uses thereof".
Patent | Date |
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Antisense oligonucleotides targeting alpha-synuclein and uses thereof Grant 11,447,775 - Olson , et al. September 20, 2 | 2022-09-20 |
Angptl2 Antisense Oligonucleotides And Uses Thereof App 20220213484 - ANDERSON; Brian R. ;   et al. | 2022-07-07 |
Novel Process for Preparing Rhenium Chelated MAG3 Oligonucleotides App 20220194972 - Hansen; Dennis Jul ;   et al. | 2022-06-23 |
Novel Process for Preparing Nucleotide P(V) Monomers App 20220194976 - Katkevica; Dace ;   et al. | 2022-06-23 |
Antisense oligonucleotides targeting alpha-synuclein and uses thereof Grant 11,359,197 - Olson , et al. June 14, 2 | 2022-06-14 |
Neoantigen Engineering Using Splice Modulating Compounds App 20220160870 - Koch; Troels ;   et al. | 2022-05-26 |
Oligonucleotides For Inducing Paternal Ube3a Expression App 20220146496 - Costa; Veronica ;   et al. | 2022-05-12 |
Alpha-synuclein Antisense Oligonucleotides And Uses Thereof App 20220119811 - HAGEDORN; Peter ;   et al. | 2022-04-21 |
Phosphonoacetate Gapmer Oligonucleotides App 20220112493 - BLEICHER; Konrad ;   et al. | 2022-04-14 |
Novel Phosphoramidites App 20220073916 - BLEICHER; Konrad ;   et al. | 2022-03-10 |
Stereodefining L-monomers Grant 11,267,843 - Albaek , et al. March 8, 2 | 2022-03-08 |
Enhanced coupling of stereodefined oxazaphospholidine phosphoramidite monomers to nucleoside or oligonucleotide Grant 11,261,209 - Ravn , et al. March 1, 2 | 2022-03-01 |
Antisense Oligonucleotides For Modulating Htra1 Expression App 20220042022 - Sanchez; Ruben Alvarez ;   et al. | 2022-02-10 |
Antisense Oligomers Targeting Pcsk9 App 20220025376 - ALB K; Nanna ;   et al. | 2022-01-27 |
Quality Control Of Lna Oligonucleotide Therapeutics Using Massively Parallel Sequencing App 20220002796 - JENSEN; Mads ;   et al. | 2022-01-06 |
Oligonucleotide Formulation Method App 20210388359 - APPELDORFF LARSEN; Inna ;   et al. | 2021-12-16 |
Camk2d Antisense Oligonucleotides And Uses Thereof App 20210378652 - OLSON; Richard E. ;   et al. | 2021-12-09 |
Oligonucleotides For Modulating Myh7 Expression App 20210371860 - HAGEDORN; Peter ;   et al. | 2021-12-02 |
Soluble TNF Receptors and Their Use in Treatment of Disease App 20210363222 - Orum; Henrik ;   et al. | 2021-11-25 |
Pyridinium Salts As Activators In The Synthesis Of Stereodefined Oligonucleotides App 20210355150 - Hansen; Dennis Jul ;   et al. | 2021-11-18 |
In Vitro Toxicity Screening Assay App 20210349076 - Boess; Franziska ;   et al. | 2021-11-11 |
Oligonucleotide conjugates Grant 11,155,816 - Albaek , et al. October 26, 2 | 2021-10-26 |
Oligonucleotide Synthesis App 20210309690 - Bleicher; Konrad ;   et al. | 2021-10-07 |
Rapid Unylinker Cleavage App 20210292357 - Meldgaard; Michael ;   et al. | 2021-09-23 |
Oligonucleotides Comprising A Phosphorotrithioate Internucleoside Linkage App 20210292358 - Bleicher; Konrad ;   et al. | 2021-09-23 |
Massively Parallel Discovery Methods For Oligonucleotide Therapeutics App 20210269851 - JENSEN; Mads ;   et al. | 2021-09-02 |
Microrna-134 Biomarker App 20210270845 - Worm; Jesper ;   et al. | 2021-09-02 |
Antisense oligomers targeting PCSK9 Grant 11,091,764 - Alb.ae butted.k , et al. August 17, 2 | 2021-08-17 |
Oligonucleotide Conjugates App 20210238601 - Albaek; Nanna ;   et al. | 2021-08-05 |
Oligonucleotides Comprising A Phosphorotrithioate Internucleoside Linkage App 20210221837 - BLEICHER; Konrad ;   et al. | 2021-07-22 |
CAMK2D antisense oligonucleotides and uses thereof Grant 11,058,767 - Olson , et al. July 13, 2 | 2021-07-13 |
Orthogonal Protecting Groups For The Preparation Of Stereodefined Phosphorothioate Oligonucleotides App 20210179658 - Bleicher; Konrad ;   et al. | 2021-06-17 |
Antisense Oligonucleotides Targeting Alpha-Synuclein and Uses Thereof App 20210180065 - OLSON; Richard E. ;   et al. | 2021-06-17 |
Novel Thiophosphoramidites App 20210115438 - BLEICHER; Konrad ;   et al. | 2021-04-22 |
Oligonucleotides For Modulating Pias4 Expression App 20210095274 - HAGEDORN; Peter ;   et al. | 2021-04-01 |
Antisense Oligonucleotides Targeting Srebp1 App 20210095277 - LINDHOLM; Eva Marie W. ;   et al. | 2021-04-01 |
Oligonucleotides For Modulating Erc1 Expression App 20210095276 - HAGEDORN; Peter ;   et al. | 2021-04-01 |
Oligonucleotides For Modulating Gsk3b Expression App 20210095275 - HAGEDORN; Peter ;   et al. | 2021-04-01 |
In vitro toxicity screening assay Grant 10,955,407 - Boess , et al. March 23, 2 | 2021-03-23 |
Pharmaceutical Composition App 20210071181 - ELMEN; Joacim ;   et al. | 2021-03-11 |
Massively Parallel Discovery Methods For Oligonucleotide Therapeutics App 20210071247 - JENSEN; Mads ;   et al. | 2021-03-11 |
Oligonucleotide Conjugation Process App 20210040137 - Hansen; Dennis Jul ;   et al. | 2021-02-11 |
Oligonucleotides For Modulating Fndc3b Expression App 20200385714 - HAGEDORN; Peter ;   et al. | 2020-12-10 |
Antisense Oligonucleotides Targeting Alpha-synuclein And Uses Thereof App 20200362347 - OLSON; Richard E. ;   et al. | 2020-11-19 |
Antisense Oligonucleotides Targeting Alpha-synuclein And Uses Thereof App 20200354720 - OLSON; Richard E. ;   et al. | 2020-11-12 |
Oligonucleotides For Inducing Paternal Ube3a Expression App 20200348286 - Costa; Veronica ;   et al. | 2020-11-05 |
Oligonucleotides Comprising A Phosphorodithioate Internucleoside Linkage App 20200339982 - BLEICHER; Konrad ;   et al. | 2020-10-29 |
Chiral library screen Grant 10,815,481 - Hansen , et al. October 27, 2 | 2020-10-27 |
Gapmer Oligonucleotides Comprising A Phosphorodithioate Internucleoside Linkage App 20200332289 - BLEICHER; Konrad ;   et al. | 2020-10-22 |
Stereodefined Sub-motif Optimisation Methods App 20200318103 - Bleicher; Konrad ;   et al. | 2020-10-08 |
LNA-G Process App 20200318109 - Hansen; Dennis Jul ;   et al. | 2020-10-08 |
Acyl-protected L-lna-guanosine L-monomers App 20200291056 - Albaek; Nanna ;   et al. | 2020-09-17 |
Splice Switching Oligomers for TNF Superfamily Receptors and Their Use in Treatment of Disease App 20200283776 - Sazani; Peter L. ;   et al. | 2020-09-10 |
Oligonucleotides for inducing paternal UBE3A expression Grant 10,739,332 - Costa , et al. A | 2020-08-11 |
Antisense Oligomers Targeting Pcsk9 App 20200248186 - Kind Code | 2020-08-06 |
Oligonucleotides for inducing paternal UBE3A expression Grant 10,718,753 - Costa , et al. | 2020-07-21 |
Antisense Oligonucleotides For Modulating Rela Expression App 20200216845 - LINDHOLM; Eva Marie W. ;   et al. | 2020-07-09 |
Antisense Oligonucleotides For Modulating Htra1 Expression App 20200157546A1 - | 2020-05-21 |
Multiple Coupling & Oxidation Method App 20200148714 - Hansen; Dennis Jul ;   et al. | 2020-05-14 |
Oligonucleotide conjugation process Grant 10,577,388 - Hansen , et al. | 2020-03-03 |
Oligonucleotides For Inducing Paternal Ube3a Expression App 20200057052 - Costa; Veronica ;   et al. | 2020-02-20 |
Methods of Selecting Therapeutic Molecules App 20190383797 - OLSON; Richard E. ;   et al. | 2019-12-19 |
Antisense Oligonucleotides For Modulating Nfkb1 Expression App 20190367920 - LINDHOLM; Eva Marie W. ;   et al. | 2019-12-05 |
Oligonucleotides for inducing paternal UBE3A expression Grant 10,494,633 - Costa , et al. De | 2019-12-03 |
Splice Switching Oligomers For Tnf Superfamily Receptors And Their Use In Treatment Of Disease App 20190359986 - Orum; Henrik ;   et al. | 2019-11-28 |
Antisense Oligonucleotides For Modulating Nfkb2 Expression App 20190345495 - LINDHOLM; Eva Marie W. ;   et al. | 2019-11-14 |
Antisense Oligonucleotides For Modulating Relb Expression App 20190345496 - LINDHOLM; Eva Marie W. ;   et al. | 2019-11-14 |
Antisense Oligonucleotides For Modulating Rel Expression App 20190338286 - LINDHOLM; Eva Marie W. ;   et al. | 2019-11-07 |
Micromirs Grant 10,450,564 - Obad , et al. Oc | 2019-10-22 |
Antisense oligomers targeting PCSK9 Grant 10,443,058 - Alb.ae butted.k , et al. Oc | 2019-10-15 |
Soluble TNF Receptors and Their Use in Treatment of Disease App 20190309047 - Orum; Henrik ;   et al. | 2019-10-10 |
Oligonucleotides For Inducing Paternal Ube3a Expression App 20190310244 - Costa; Veronica ;   et al. | 2019-10-10 |
5`S-LNA nucleotides and oligonucleotides App 20190292213 - Bleicher; Konrad ;   et al. | 2019-09-26 |
Therapeutic Oligonucleotides Capture And Detection App 20190284621 - JENSEN; Mads Aaboe ;   et al. | 2019-09-19 |
Camk2d Antisense Oligonucleotides And Uses Thereof App 20190275148 - Olson; Richard E. ;   et al. | 2019-09-12 |
Methods of treatment using antisense oligomers and conjugates targeting PCSK9 Grant 10,385,342 - Alb.ae butted.k , et al. A | 2019-08-20 |
Manufacture of antisense oligomers and conjugates targeting PCSK9 Grant 10,370,668 - Alb.ae butted.k , et al. | 2019-08-06 |
Enhanced Coupling Of Stereodefined Oxazaphospholidine Phosphoramidite Monomers To Nucleoside Or Oligonucleotide App 20190153012 - RAVN; Jacob ;   et al. | 2019-05-23 |
NUCLEIC ACID MOLECULE FOR REDUCTION OF PAPD5 AND PAPD7 mRNA FOR TREATING HEPATITIS B INFECTION App 20190111073 - Kammler; Susanne ;   et al. | 2019-04-18 |
Pharmaceutical Composition App 20190071672 - Elmen; Joacim ;   et al. | 2019-03-07 |
Antisense Oligonucleotides For Modulating Htra1 Expression App 20190055564 - Sanchez; Ruben Alvarez ;   et al. | 2019-02-21 |
LNA-G Process App 20190055550 - Hansen; Dennis Jul ;   et al. | 2019-02-21 |
In Vitro Toxicity Screening Assay App 20190025288 - Boess; Franziska ;   et al. | 2019-01-24 |
Splice Switching Oligomers for TNF Superfamily Receptors and Their Use in Treatment of Disease App 20190017052 - Sazani; Peter L. ;   et al. | 2019-01-17 |
Manufacture of Antisense Oligomers and Conjugates Targeting PCSK9 App 20180312846 - ALB K; Nanna ;   et al. | 2018-11-01 |
Methods of Treatment Using Antisense Oligomers and Conjugates Targeting PCSK9 App 20180312847 - ALB K; Nanna ;   et al. | 2018-11-01 |
Oligonucleotide Conjugation Process App 20180305392 - Hansen; Dennis Jul ;   et al. | 2018-10-25 |
Oligonucleotide conjugates Grant 10,077,443 - Albaek , et al. September 18, 2 | 2018-09-18 |
Oligonucleotide Conjugates App 20180251764 - Albaek; Nanna ;   et al. | 2018-09-06 |
Antisense Design App 20180237777 - Christensen; Signe M. ;   et al. | 2018-08-23 |
Antisense Design App 20180237778 - Christensen; Signe M. ;   et al. | 2018-08-23 |
Antisense Oligomers And Conjugates Targeting Pcsk9 App 20180216116 - Albaek; Nanna ;   et al. | 2018-08-02 |
Micromirs App 20180201928 - Obad; Susanna ;   et al. | 2018-07-19 |
Pharmaceutical Composition App 20180195062 - Elmen; Joacim ;   et al. | 2018-07-12 |
Tau Antisense Oligomers And Uses Thereof App 20180161356 - Olson; Richard E. ;   et al. | 2018-06-14 |
Antisense design Grant 9,994,850 - Christensen , et al. June 12, 2 | 2018-06-12 |
Stereospecific Phosphorothioate LNA App 20180112217 - Hansen; Henrik Frydenlund ;   et al. | 2018-04-26 |
Antisense design Grant 9,951,333 - Christensen , et al. April 24, 2 | 2018-04-24 |
Potent LNA oligonucleotides for the inhibition of HIF-1A expression Grant 9,938,527 - Westergaard , et al. April 10, 2 | 2018-04-10 |
Splice Switching Oligomers for TNF Superfamily Receptors and Their Use in Treatment of Disease App 20180051290 - Sazani; Peter L. ;   et al. | 2018-02-22 |
Antisense design Grant 9,890,383 - Christensen , et al. February 13, 2 | 2018-02-13 |
Oligonucleotide conjugates Grant 9,879,265 - Alb.ae butted.k , et al. January 30, 2 | 2018-01-30 |
Lna Oligonucleotides With Alternating Flanks App 20180023081 - HAGEDORN; Peter ;   et al. | 2018-01-25 |
LNA Gapmer Oligonucleotides Comprising Chiral Phosphorothioate Linkages App 20180016575 - Hansen; Henrik Frydenlund ;   et al. | 2018-01-18 |
Antisense Design App 20170342412 - Christensen; Signe M. ;   et al. | 2017-11-30 |
Antisense Design App 20170342413 - Christensen; Signe M. ;   et al. | 2017-11-30 |
Chiral Library Screen App 20170335323 - Hansen; Henrik Frydenlund ;   et al. | 2017-11-23 |
MICROMIRs Grant 9,790,493 - Obad , et al. October 17, 2 | 2017-10-17 |
Oligonucleotides For Reduction Of Pd-l1 Expression App 20170283496 - Pedersen; Lykke ;   et al. | 2017-10-05 |
Antisense Design App 20170275628 - Christensen; Signe M. ;   et al. | 2017-09-28 |
Short interfering RNA (siRNA) analogues Grant 9,738,894 - Elmen , et al. August 22, 2 | 2017-08-22 |
Compositions and methods for modulation of FGFR3 expression Grant 9,725,723 - Hedtjarn , et al. August 8, 2 | 2017-08-08 |
Antisense design Grant 9,708,614 - Christensen , et al. July 18, 2 | 2017-07-18 |
Soluble TNF Receptors and Their Use in Treatment of Disease App 20170198024 - Orum; Henrik ;   et al. | 2017-07-13 |
Splice Switching Oligomers for TNF Superfamily Receptors and Their Use in Treatment of Disease App 20170191067 - Sazani; Peter L. ;   et al. | 2017-07-06 |
Oligonucleotides For Inducing Paternal Ube3a Expression App 20170191064 - Costa; Veronica ;   et al. | 2017-07-06 |
Oral delivery of therapeutically effective LNA oligonucleotides Grant 9,566,293 - Hardee , et al. February 14, 2 | 2017-02-14 |
Splice Switching Oligomers For Tnf Superfamily Receptors And Their Use In Treatment Of Disease App 20170015697 - Orum; Henrik ;   et al. | 2017-01-19 |
Short Interfering RNA (siRNA) Analogues App 20170009237 - Elmen; Joacim ;   et al. | 2017-01-12 |
Potent Lna Oligonucleotides For The Inhibition Of Hif-1a Expression App 20160355819 - Westergaard; Majken ;   et al. | 2016-12-08 |
Antisense Design App 20160348111 - Christensen; Signe M. ;   et al. | 2016-12-01 |
APOB Antisense Conjugate Compounds App 20160289677 - Albaek; Nanna ;   et al. | 2016-10-06 |
Potent LNA oligonucleotides for the inhibition of HIF-1a expression Grant 9,447,138 - Westergaard , et al. September 20, 2 | 2016-09-20 |
Antisense design Grant 9,428,534 - Christensen , et al. August 30, 2 | 2016-08-30 |
Tau Antisense Oligomers and Uses Thereof App 20160237427 - OLSON; Richard E. ;   et al. | 2016-08-18 |
Antisense Design App 20160168575 - Christensen; Signe M. ;   et al. | 2016-06-16 |
Antisense Design App 20160168576 - Christensen; Signe M. ;   et al. | 2016-06-16 |
Oral delivery of therapeutically effective LNA oligonucleotides Grant 9,364,495 - Hardee , et al. June 14, 2 | 2016-06-14 |
Oligonucleotide Conjugates App 20160138025 - ALB K; Nanna ;   et al. | 2016-05-19 |
Oligonucleotide Modulators Of B-cell Cll/lymphoma 11a (bcl11a) And Uses Thereof App 20160130582 - HEDTJARN; Maj ;   et al. | 2016-05-12 |
Short interfering RNA (siRNA) analogues Grant 9,297,010 - Elmen , et al. March 29, 2 | 2016-03-29 |
Potent anti APOB antisense compounds Grant 9,290,758 - Nielsen , et al. March 22, 2 | 2016-03-22 |
Pharmaceutical Composition for Inhibition of Disease-inducing microRNAs App 20160060627 - ELMEN; Joacim ;   et al. | 2016-03-03 |
Oral Delivery of Therapeutically Effective LNA Oligonucleotides App 20160032289 - Hardee; Gregroy ;   et al. | 2016-02-04 |
Compositions And Methods For Modulation Of Fgfr3 Expression App 20150307886 - Hedtjarn; Maj ;   et al. | 2015-10-29 |
Anti Apob Antisense Conjugate Compounds App 20150291958 - Albaek; Nanna ;   et al. | 2015-10-15 |
Oligonucleotide Conjugates App 20150275212 - Albaek; Nanna ;   et al. | 2015-10-01 |
Pharmaceutical composition comprising anti-miRNA antisense oligonucleotides Grant 9,133,455 - Elmen , et al. September 15, 2 | 2015-09-15 |
Soluble TNF Receptors and Their Use in Treatment of Disease App 20150166634 - Orum; Henrik ;   et al. | 2015-06-18 |
Pharmaceutical compositions for treatment of HCV patients that are poor-responders to interferon Grant 9,034,837 - Hildebrandt-Eriksen , et al. May 19, 2 | 2015-05-19 |
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