Patent | Date |
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Anti-mesothelin polypeptides and proteins Grant 11,390,683 - Pastan , et al. July 19, 2 | 2022-07-19 |
Cross Species Single Domain Antibodies Targeting Mesothelin For Treating Solid Tumors App 20220064324 - Ho; Mitchell ;   et al. | 2022-03-03 |
Combination Therapy of Immunotoxin and Checkpoint Inhibitor App 20210338811 - Bigner; Darell ;   et al. | 2021-11-04 |
Combination therapy of immunotoxin and checkpoint inhibitor Grant 11,065,332 - Bigner , et al. July 20, 2 | 2021-07-20 |
Anti-BCMA polypeptides and proteins Grant 10,925,969 - Pastan , et al. February 23, 2 | 2021-02-23 |
Modified Pseudomonas Exotoxin A App 20210024648 - Pastan; Ira H. ;   et al. | 2021-01-28 |
M971 Chimeric Antigen Receptors App 20200283522 - Orentas; Rimas J. ;   et al. | 2020-09-10 |
Anti-mesothelin Polypeptides And Proteins App 20200247901 - Kind Code | 2020-08-06 |
Immunotoxins With Albumin Binding Domain App 20200223937 - Pastan; Ira H. ;   et al. | 2020-07-16 |
M971 chimeric antigen receptors Grant 10,703,816 - Orentas , et al. | 2020-07-07 |
Recombinant immunotoxin targeting mesothelin Grant 10,683,362 - Pastan , et al. | 2020-06-16 |
Modified Pseudomonas Exotoxin A App 20200181280 - Pastan; Ira H. ;   et al. | 2020-06-11 |
Human monoclonal antibodies specific for CD22 Grant 10,494,435 - Dimitrov , et al. De | 2019-12-03 |
Pseudomonas exotoxin A with less immunogenic T cell and/or B cell epitopes Grant 10,428,119 - Pastan , et al. October 1, 2 | 2019-10-01 |
M971 Chimeric Antigen Receptors App 20190085078 - Orentas; Rimas J. ;   et al. | 2019-03-21 |
Certain Improved Human Bispecific EGFRvIII Antibody Engaging Molecules App 20180362659 - Bigner; Darell D. ;   et al. | 2018-12-20 |
Anti-bcma Polypeptides And Proteins App 20180318435 - Pastan; Ira H. ;   et al. | 2018-11-08 |
Combination Therapy Of Immunotoxin And Checkpoint Inhibitor App 20180311346 - Bigner; Darell ;   et al. | 2018-11-01 |
Pseudomonas exotoxin A with less immunogenic B cell epitopes Grant 10,111,927 - Pastan , et al. October 30, 2 | 2018-10-30 |
Dual specific immunotoxin for brain tumor therapy Grant 10,072,084 - Bigner , et al. September 11, 2 | 2018-09-11 |
M971 chimeric antigen receptors Grant 10,072,078 - Orentas , et al. September 11, 2 | 2018-09-11 |
Methods for using antibodies for 3' iso-LM1 and 3', 6'-iso-LD1tumor gangliosides Grant 10,052,382 - Bigner , et al. August 21, 2 | 2018-08-21 |
Human bispecific EGFRvIII and CD3 antibody engaging molecules Grant 10,053,514 - Bigner , et al. August 21, 2 | 2018-08-21 |
Anti-CD22 chimeric antigen receptors Grant 9,868,774 - Orentas , et al. January 16, 2 | 2018-01-16 |
Pseudomonas Exotoxin A With Less Immunogenic T Cell And/or B Cell Epitopes App 20170369535 - Pastan; Ira H. ;   et al. | 2017-12-28 |
Mesothelin domain-specific monoclonal antibodies and use thereof Grant 9,803,022 - Ho , et al. October 31, 2 | 2017-10-31 |
Pseudomonas exotoxin a with less immunogenic T cell and/or B cell epitopes Grant 9,765,123 - Pastan , et al. September 19, 2 | 2017-09-19 |
Pseudomonas Exotoxin A With Less Immunogenic B Cell Epitopes App 20170216398 - Pastan; Ira H. ;   et al. | 2017-08-03 |
Human bispecific EGFRvIII antibody and CD3 engaging molecules Grant 9,676,858 - Bigner , et al. June 13, 2 | 2017-06-13 |
Human Monoclonal Antibodies Specific For Cd22 App 20170145097 - Dimitrov; Dimiter S. ;   et al. | 2017-05-25 |
Pseudomonas exotoxin A with less immunogenic B cell epitopes Grant 9,657,066 - Pastan , et al. May 23, 2 | 2017-05-23 |
Human monoclonal antibodies specific for CD22 Grant 9,598,492 - Dimitrov , et al. March 21, 2 | 2017-03-21 |
Modified Pseudomonas Exotoxin A App 20170051072 - Pastan; Ira H. ;   et al. | 2017-02-23 |
Dual Specific Immunotoxin for Brain Tumor Therapy App 20170051064 - Bigner; Darell D. ;   et al. | 2017-02-23 |
Dual specific immunotoxin for brain tumor therapy Grant 9,492,564 - Bigner , et al. November 15, 2 | 2016-11-15 |
Antibodies for Tumor Gangliosides App 20160272730 - Bigner; Darell ;   et al. | 2016-09-22 |
Antibody for 3'-isoLM1 and 3',6'-iso-LD1 gangliosides Grant 9,441,048 - Bigner , et al. September 13, 2 | 2016-09-13 |
Mesothelin antibodies and methods for eliciting potent antitumor activity Grant 9,416,190 - Ho , et al. August 16, 2 | 2016-08-16 |
Mesothelin Domain-specific Monoclonal Antibodies And Use Thereof App 20160229919 - Ho; Mitchell ;   et al. | 2016-08-11 |
Mesothelin domain-specific monoclonal antibodies and use thereof Grant 9,409,992 - Ho , et al. August 9, 2 | 2016-08-09 |
Pseudomonas Exotoxin A With Less Immunogenic T Cell And/or B Cell Epitopes App 20160215025 - Pastan; Ira H. ;   et al. | 2016-07-28 |
Immunogenic POTE peptides and methods of use Grant 9,394,352 - Berzofsky , et al. July 19, 2 | 2016-07-19 |
Modified Pseudomonas exotoxin A Grant 9,388,222 - Pastan , et al. July 12, 2 | 2016-07-12 |
Certain Improved Human Bispecific EGFRvIII Antibody Engaging Molecules App 20160168263 - Bigner; Darell D. ;   et al. | 2016-06-16 |
Anti-mesothelin chimeric antigen receptors Grant 9,359,447 - Feldman , et al. June 7, 2 | 2016-06-07 |
Human Monoclonal Antibodies Specific For Cd22 App 20160145338 - Dimitrov; Dimiter S. ;   et al. | 2016-05-26 |
Pseudomonas exotoxin A with less immunogenic T cell and/or B cell epitopes Grant 9,346,859 - Pastan , et al. May 24, 2 | 2016-05-24 |
Human monoclonal antibodies specific for CD22 Grant 9,279,019 - Dimitrov , et al. March 8, 2 | 2016-03-08 |
Pseudomonas Exotoxin A With Less Immunogenic B Cell Epitopes App 20160046677 - Pastan; Ira H. ;   et al. | 2016-02-18 |
Bispecific EGFRvIII x CD3 antibody engaging molecules Grant 9,249,217 - Bigner , et al. February 2, 2 | 2016-02-02 |
Anti-Podoplanin Antibodies and Methods of Use App 20150368353 - BIGNER; Darell ;   et al. | 2015-12-24 |
Pseudomonas exotoxin A with less immunogenic B cell epitopes Grant 9,206,240 - Pastan , et al. December 8, 2 | 2015-12-08 |
Immunogenic peptides and methods of use Grant 9,175,057 - Schlom , et al. November 3, 2 | 2015-11-03 |
M971 Chimeric Antigen Receptors App 20150299317 - Orentas; Rimas J. ;   et al. | 2015-10-22 |
Mesothelin Antibodies And Methods For Eliciting Potent Antitumor Activity App 20150274836 - Ho; Mitchell ;   et al. | 2015-10-01 |
Mesothelin Domain-specific Monoclonal Antibodies And Use Thereof App 20150252118 - Ho; Mitchell ;   et al. | 2015-09-10 |
Antibodies and immunotoxins that target human glycoprotein NMB Grant 9,115,196 - Kuan , et al. August 25, 2 | 2015-08-25 |
HUMAN BISPECIFIC EGFRvIII ANTIBODY ENGAGING MOLECULES App 20150132306 - Bigner; Darell ;   et al. | 2015-05-14 |
Modified Pseudomonas Exotoxin A App 20150099707 - Pastan; Ira H. ;   et al. | 2015-04-09 |
Anti-mesothelin Chimeric Antigen Receptors App 20150031624 - Feldman; Steven A. ;   et al. | 2015-01-29 |
Pseudomonas exotoxin a with reduced immunogenicity Grant 8,936,792 - Pastan , et al. January 20, 2 | 2015-01-20 |
Immunogenic Pote Peptides And Methods Of Use App 20150010590 - Berzofsky; Jay A. ;   et al. | 2015-01-08 |
Mutated Pseudomonas exotoxins with reduced antigenicity Grant 8,907,060 - Pastan , et al. December 9, 2 | 2014-12-09 |
Dual Specific Immunotoxin for Brain Tumor Therapy App 20140322248 - BIGNER; Darell ;   et al. | 2014-10-30 |
Immunogenic POTE peptides and methods of use Grant 8,871,902 - Berzofsky , et al. October 28, 2 | 2014-10-28 |
Deletions in domain II of pseudomonas exotoxin a that remove immunogenic epitopes Grant 8,871,906 - Pastan , et al. October 28, 2 | 2014-10-28 |
Immunogenic Epitopes Of Ngep Antigen App 20140287029 - Schlom; Jeffrey ;   et al. | 2014-09-25 |
Anti-cd22 Chimeric Antigen Receptors App 20140274909 - Orentas; Rimas J. ;   et al. | 2014-09-18 |
Pseudomonas Exotoxin A With Less Immunogenic B Cell Epitopes App 20140213529 - Pastan; Ira H. ;   et al. | 2014-07-31 |
Recombinant Immunotoxin Targeting Mesothelin App 20140154248 - Pastan; Ira H. ;   et al. | 2014-06-05 |
Pseudomonas Exotoxin A With Less Immunogenic T Cell And/or B Cell Epitopes App 20140094417 - Pastan; Ira H. ;   et al. | 2014-04-03 |
Anti-podoplanin Antibodies And Methods Of Use App 20140017266 - Bigner; Darell ;   et al. | 2014-01-16 |
Antibodies For Tumor Gangliosides App 20140010829 - Bigner; Darell ;   et al. | 2014-01-09 |
Human Monoclonal Antibodies Specific For Cd22 App 20130315921 - Dimitrov; Dimiter S. ;   et al. | 2013-11-28 |
Human monoclonal antibodies specific for CD22 Grant 8,591,889 - Dimitrov , et al. November 26, 2 | 2013-11-26 |
Antibodies and Immunotoxins that Target Human Glycoprotein NMB App 20130245244 - KUAN; Chien-Tsun ;   et al. | 2013-09-19 |
Immunogenic Peptides of Xage-1 App 20130171178 - Berzofsky; Jay A. ;   et al. | 2013-07-04 |
Antibodies and immunotoxins that target human glycoprotein NMB Grant 8,445,216 - Kuan , et al. May 21, 2 | 2013-05-21 |
Immunogenic Pote Peptides And Methods Of Use App 20130039936 - Berzofsky; Jay A. ;   et al. | 2013-02-14 |
Dual Specific Immunotoxin for Brain Tumor Therapy App 20130022598 - Bigner; Darell ;   et al. | 2013-01-24 |
Human anti-mesothelin monoclonal antibodies Grant 8,357,783 - Dimitrov , et al. January 22, 2 | 2013-01-22 |
Pseudomonas Exotoxin A With Reduced Immunogenicity App 20120263674 - Pastan; Ira H. ;   et al. | 2012-10-18 |
Mutated Anti-cd22 Antibodies With Increased Affinity To Cd22-expressing Leukemia Cells App 20120258106 - Pastan; Ira H ;   et al. | 2012-10-11 |
Antibodies And Immunotoxins That Target Human Glycoprotein Nmb App 20120122121 - KUAN; Chien-Tsun ;   et al. | 2012-05-17 |
Antibodies and immunotoxins that target human glycoprotein NMB Grant 8,039,593 - Kuan , et al. October 18, 2 | 2011-10-18 |
Mutated anti-cd22 antibodies and immunoconjugates Grant 7,982,011 - Pastan , et al. July 19, 2 | 2011-07-19 |
Immunogenic Peptides And Methods Of Use App 20110165117 - Schlom; Jeffrey ;   et al. | 2011-07-07 |
Immunogenic peptides and methods of use Grant 7,910,692 - Schlom , et al. March 22, 2 | 2011-03-22 |
Mutated Anti-cd22 Antibodies With Increased Affinity To Cd22-expressing Leukemia Cells App 20110065185 - Pastan; Ira H. ;   et al. | 2011-03-17 |
Gene expressed in prostate cancer and methods of use Grant 7,897,355 - Pastan , et al. March 1, 2 | 2011-03-01 |
Human Anti-mesothelin Monoclonal Antibodies App 20110020361 - Dimitrov; Dimiter S. ;   et al. | 2011-01-27 |
Human Monoclonal Antibodies Specific For Cd22 App 20110020344 - Dimitrov; Dimiter S. ;   et al. | 2011-01-27 |
Gene expressed in prostate cancer and methods of use Grant 7,816,087 - Pastan , et al. October 19, 2 | 2010-10-19 |
Deletions In Domain Ii Of Pseudomonas Exotoxin A That Remove Immunogenic Epitopes App 20100215656 - Pastan; Ira H. ;   et al. | 2010-08-26 |
Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use Grant 7,709,252 - Pastan , et al. May 4, 2 | 2010-05-04 |
Anti-Tumor Antibodies App 20100047164 - Bigner; Darell ;   et al. | 2010-02-25 |
Dual Specific Immunotoxin for Brain Tumor Therapy App 20090269343 - Bigner; Darell ;   et al. | 2009-10-29 |
Antibodies And Immunotoxins That Target Human Glycoprotein Nmb App 20090252750 - Kuan; Chien-Tsun ;   et al. | 2009-10-08 |
Gene Expressed In Prostate Cancer And Methods Of Use App 20090202552 - Pastan; Ira H. ;   et al. | 2009-08-13 |
Mutated pseudomonas exotoxins with reduced antigenicity App 20090142341 - Pastan; Ira H. ;   et al. | 2009-06-04 |
Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the Fv to lower the isoelectric point Grant 7,521,054 - Pastan , et al. April 21, 2 | 2009-04-21 |
Anti-mesothelin antibodies useful for immunological assays App 20090047211 - Pastan; Ira H. ;   et al. | 2009-02-19 |
Immunogenic Peptides And Methods Of Use App 20090035266 - Schlom; Jeffrey ;   et al. | 2009-02-05 |
Mutated Anti-CD22 Antibodies With Increased Affinity To CD22-Expressing Leukemia Cells App 20090004734 - Pastan; Ira H. ;   et al. | 2009-01-01 |
Anti-CD30 stalk and anti-CD30 antibodies suitable for use in immunotoxins Grant 7,470,775 - Pastan , et al. December 30, 2 | 2008-12-30 |
Antibodies, Including Fv Molecules, And Immunoconjugates Having High Binding Affinity For Mesothelin And Methods For Their Use App 20080261245 - Pastan; Ira H. ;   et al. | 2008-10-23 |
Polymer-Linked Pseudomonas Exotoxin Immunotoxin App 20080125363 - Filpula; David Ray ;   et al. | 2008-05-29 |
Antibodies, including Fv molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use Grant 7,368,110 - Pastan , et al. May 6, 2 | 2008-05-06 |
Mutated anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cells Grant 7,355,012 - Pastan , et al. April 8, 2 | 2008-04-08 |
Page-4, an X-linked gage-like gene expressed in normal and neoplastic prostate, testis and uterus, and uses therefor App 20070248972 - Pastan; Ira H. ;   et al. | 2007-10-25 |
Mutated anti-cd22 antibodies and immunoconjugates App 20070189962 - Pastan; Ira H. ;   et al. | 2007-08-16 |
Elisa assay of serum soluble cd22 to assess tumor burnden/relapse in subjects with leukemia and lymphoma App 20050244828 - Kreitman, Robert J. ;   et al. | 2005-11-03 |
Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use App 20050214304 - Pastan, Ira H. ;   et al. | 2005-09-29 |
Mutated anti-cd22 antibodies with increased affinity to cd22-expressing leukemia cells App 20050118182 - Pastan, Ira H ;   et al. | 2005-06-02 |
Gene expressed in breast cancer and methods of use App 20050053988 - Pastan, Ira H. ;   et al. | 2005-03-10 |
Gene expressed in prostate cancer and methods of use App 20040241702 - Pastan, Ira H. ;   et al. | 2004-12-02 |
Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use Grant 6,809,184 - Pastan , et al. October 26, 2 | 2004-10-26 |
Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the fv to lower the isoelectric point App 20040091489 - Pastan, Ira H. ;   et al. | 2004-05-13 |
Methods of making recombinant disulfide-stabilized polypeptide fragments having binding specificity Grant 6,558,672 - Pastan , et al. May 6, 2 | 2003-05-06 |
Recombinant disulfide-stabilized polypeptide fragments having binding specificity Grant 6,147,203 - Pastan , et al. November 14, 2 | 2000-11-14 |
Recombinant antibody-toxin fusion protein Grant 5,863,745 - Fitzgerald , et al. January 26, 1 | 1999-01-26 |
Recombinant pseudomonas exotoxin with increased activity Grant 5,854,044 - Pastan , et al. December 29, 1 | 1998-12-29 |
Recombinant pseudomonas exotoxin with increased activity Grant 5,821,238 - Pastan , et al. October 13, 1 | 1998-10-13 |
Recombinant disulfide-stabilized polypeptide fragments having binding specificity Grant 5,747,654 - Pastan , et al. May 5, 1 | 1998-05-05 |
Fusion proteins comprising circularly permuted ligands Grant 5,635,599 - Pastan , et al. June 3, 1 | 1997-06-03 |
Recombinant pseudomonas exotoxin with increased activity Grant 5,602,095 - Pastan , et al. February 11, 1 | 1997-02-11 |
Monoclonal antibodies to prostate cells Grant 5,489,525 - Pastan February 6, 1 | 1996-02-06 |
Recombinant chimeric proteins deliverable across cellular membranes into cytosol of target cells Grant 5,328,984 - Pastan , et al. July 12, 1 | 1994-07-12 |
Compositions for clones containing DNA sequences associated with multidrug resistance in human cells Grant 5,206,352 - Roninson , et al. April 27, 1 | 1993-04-27 |
Anti-human ovarian cancer immunotoxins and methods of use thereof Grant 4,958,009 - Bjorn , et al. * September 18, 1 | 1990-09-18 |
Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects Grant 4,892,827 - Pastan , et al. January 9, 1 | 1990-01-09 |