Manoharan; Muthiah
Patent Applications and Registrations
Patent applications and USPTO patent grants for Manoharan; Muthiah.The latest application filed is for "delivery of oligonucleotides to the striatum".
Company Profile
67.200.200
- Manoharan; Muthiah - Cambridge MA
- Manoharan; Muthiah - Weston MA
- Manoharan; Muthiah - Carlsbad CA US
Patent Activity
| Patent | Date |
|---|---|
| Delivery Of Oligonucleotides To The Striatum App 20220307024 - Nair; Jayaprakash K. ; et al. | 2022-09-29 |
| Modified RNA Agents with Reduced Off-Target Effect App 20220290145 - MATSUDA; Shigeo ; et al. | 2022-09-15 |
| Modified double-stranded RNA agents Grant 11,427,822 - Maier , et al. August 30, 2 | 2022-08-30 |
| Lipid containing formulations Grant 11,420,931 - Manoharan , et al. August 23, 2 | 2022-08-23 |
| Reversir Tm Compounds App 20220259589 - JADHAV; Vasant ; et al. | 2022-08-18 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20220249670 - Maier; Martin ; et al. | 2022-08-11 |
| Modified RNAi agents Grant 11,406,716 - Rajeev , et al. August 9, 2 | 2022-08-09 |
| Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof Grant 11,408,001 - Fitzgerald , et al. August 9, 2 | 2022-08-09 |
| Modified double-stranded RNA agents Grant 11,401,517 - Maier , et al. August 2, 2 | 2022-08-02 |
| Biodegradable lipids for the delivery of active agents Grant 11,400,158 - Maier , et al. August 2, 2 | 2022-08-02 |
| Biodegradable lipids for the delivery of active agents Grant 11,382,979 - Maier , et al. July 12, 2 | 2022-07-12 |
| HIGH DENSITY LIPOPROTEIN BINDING PROTEIN (HDLBP/VIGILIN) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20220202847 - Manoharan; Muthiah ; et al. | 2022-06-30 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20220175930 - Maier; Martin ; et al. | 2022-06-09 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20220175929 - Maier; Martin ; et al. | 2022-06-09 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20220175928 - Maier; Martin ; et al. | 2022-06-09 |
| Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20220162603 - Allerson; Charles ; et al. | 2022-05-26 |
| Carbohydrate Conjugates As Delivery Agents For Oligonucleotides App 20220143189 - MANOHARAN; Muthiah ; et al. | 2022-05-12 |
| Reversir Tm Compounds App 20220127604 - JADHAV; Vasant ; et al. | 2022-04-28 |
| Extrahepatic Delivery App 20220125823 - NAIR; Jayaprakash K. ; et al. | 2022-04-28 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20220125927 - Maier; Martin ; et al. | 2022-04-28 |
| Modified iRNA agents Grant 11,312,957 - Manoharan , et al. April 26, 2 | 2022-04-26 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20220111053 - MAIER; MARTIN ; et al. | 2022-04-14 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20220105187 - Maier; Martin ; et al. | 2022-04-07 |
| Multi-targeted Single Entity Conjugates App 20220106593 - JADHAV; Vasant ; et al. | 2022-04-07 |
| COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20220090068 - Fitzgerald; Kevin ; et al. | 2022-03-24 |
| Modified Double-stranded Rna Agents App 20220056448 - MAIER; Martin ; et al. | 2022-02-24 |
| Compositions And Methods For Inhibition Of Expression Of Apolipoprotein C-iii (apoc3) Genes App 20220049253 - Bettencourt; Brian ; et al. | 2022-02-17 |
| Biodegradable lipids for the delivery of active agents Grant 11,246,933 - Maier , et al. February 15, 2 | 2022-02-15 |
| Lipid Compositions App 20220040308 - Manoharan; Muthiah ; et al. | 2022-02-10 |
| Lipids And Compositions For The Delivery Of Therapeutics App 20220023427 - Manoharan; Muthiah ; et al. | 2022-01-27 |
| Carbohydrate Conjugates As Delivery Agents For Oligonucleotides App 20220008541 - MANOHARAN; Muthiah ; et al. | 2022-01-13 |
| Modified Double-stranded Rna Agents App 20220002727 - MAIER; Martin ; et al. | 2022-01-06 |
| High density lipoprotein binding protein (Hdlbp/Vigilin) iRNA compositions and methods of use thereof Grant 11,207,342 - Manoharan , et al. December 28, 2 | 2021-12-28 |
| Complement component C5 iRNA compositions and methods of use thereof Grant 11,162,098 - Fitzgerald , et al. November 2, 2 | 2021-11-02 |
| SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20210317452 - Sehgal; Alfica ; et al. | 2021-10-14 |
| Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof Grant 11,142,766 - Fitzgerald , et al. October 12, 2 | 2021-10-12 |
| Carbohydrate conjugates as delivery agents for oligonucleotides Grant 11,110,174 - Manoharan , et al. September 7, 2 | 2021-09-07 |
| SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20210269796 - Schlegel; Mark K. ; et al. | 2021-09-02 |
| iRNA AGENTS WITH BIOCLEAVABLE TETHERS App 20210254065 - MANOHARAN; Muthiah ; et al. | 2021-08-19 |
| SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20210254063 - Akinc; Akin ; et al. | 2021-08-19 |
| Compositions And Methods For Improving Strand Biased App 20210238594 - PARMAR; Rubina G. ; et al. | 2021-08-05 |
| Modified Rna Agents With Reduced Off-target Effect App 20210238595 - MATSUDA; Shigeo ; et al. | 2021-08-05 |
| Lipids and compositions for the delivery of therapeutics Grant 11,077,197 - Manoharan , et al. August 3, 2 | 2021-08-03 |
| Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 11,078,485 - Allerson , et al. August 3, 2 | 2021-08-03 |
| Biodegradable lipids for the delivery of active agents Grant 11,071,784 - Maier , et al. July 27, 2 | 2021-07-27 |
| Hepatitis B virus (HBV) iRNA compositions and methods of use thereof Grant 11,060,091 - Hinkle , et al. July 13, 2 | 2021-07-13 |
| Chirally-enriched Double-stranded Rna Agents App 20210207144 - MANOHARAN; Muthiah ; et al. | 2021-07-08 |
| Multi-targeted single entity conjugates Grant 11,053,495 - Jadhav , et al. July 6, 2 | 2021-07-06 |
| Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof Grant 11,034,958 - Fitzgerald , et al. June 15, 2 | 2021-06-15 |
| Novel Lipids And Compositions For The Delivery Of Therapeutics App 20210162053 - Manoharan; Muthiah ; et al. | 2021-06-03 |
| iRNA agents with biocleavable tethers Grant 11,015,194 - Manoharan , et al. May 25, 2 | 2021-05-25 |
| Serpina1 iRNA compositions and methods of use thereof Grant 10,995,336 - Schlegel , et al. May 4, 2 | 2021-05-04 |
| APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20210108203 - Fitzgerald; Kevin ; et al. | 2021-04-15 |
| Oligonucleotides Comprising Acyclic And Abasic Nucleosides And Analogs App 20210087219 - MANOHARAN; Muthiah ; et al. | 2021-03-25 |
| Lipid compositions Grant 10,953,095 - Manoharan , et al. March 23, 2 | 2021-03-23 |
| Myostatin iRNA compositions and methods of use thereof Grant 10,933,081 - Jadhav , et al. March 2, 2 | 2021-03-02 |
| Serpina1 iRNA compositions and methods of use thereof Grant 10,920,223 - Sehgal , et al. February 16, 2 | 2021-02-16 |
| Oligonucleotides comprising acyclic and abasic nucleosides and analogs Grant 10,913,767 - Manoharan , et al. February 9, 2 | 2021-02-09 |
| Modified Double-stranded Rna Agents App 20210017519 - MAIER; Martin ; et al. | 2021-01-21 |
| Lipid Containing Formulations App 20200361854 - Manoharan; Muthiah ; et al. | 2020-11-19 |
| Lipids and compositions for the delivery of therapeutics Grant 10,835,612 - Manoharan , et al. November 17, 2 | 2020-11-17 |
| MODIFIED RNAi AGENTS App 20200353097 - RAJEEV; Kallanthottathil G. ; et al. | 2020-11-12 |
| Lipids and compositions for the delivery of therapeutics Grant 10,821,186 - Manoharan , et al. November 3, 2 | 2020-11-03 |
| Oligonucleotide-ligand conjugates and process for their preparation Grant 10,808,246 - Manoharan , et al. October 20, 2 | 2020-10-20 |
| Carbohydrate conjugates as delivery agents for oligonucleotides Grant 10,806,791 - Manoharan , et al. October 20, 2 | 2020-10-20 |
| Rnai Agents, Compositions And Methods Of Use Thereof For Treating Transthyretin (ttr) Associated Diseases App 20200318111 - Rajeev; Kallanthottathil G. ; et al. | 2020-10-08 |
| Carbohydrate Conjugates As Delivery Agents For Oligonucleotides App 20200297853 - MANOHARAN; Muthiah ; et al. | 2020-09-24 |
| HEPATITIS D VIRUS (HDV) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20200291405 - Hinkle; Gregory ; et al. | 2020-09-17 |
| Methods And Compositions For Detecting Anti-drug Antibodies App 20200291449 - Rajeev; Kallanthottathil G. ; et al. | 2020-09-17 |
| Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes App 20200263176 - Bettencourt; Brian ; et al. | 2020-08-20 |
| Therapeutic Compositions App 20200255833 - MANOHARAN; Muthiah ; et al. | 2020-08-13 |
| SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20200216844 - Akinc; Akin ; et al. | 2020-07-09 |
| APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20200199591 - Fitzgerald; Kevin ; et al. | 2020-06-25 |
| Serpina1 iRNA compositions and methods of use thereof Grant 10,683,504 - Sehgal , et al. | 2020-06-16 |
| Modified iRNA agents Grant 10,676,740 - Manoharan , et al. | 2020-06-09 |
| Modified RNAi agents Grant 10,668,170 - Rajeev , et al. | 2020-06-02 |
| Therapeutic compositions Grant 10,669,544 - Manoharan , et al. | 2020-06-02 |
| HEPATITIS B VIRUS (HBV) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20200140864 - Hinkle; Gregory ; et al. | 2020-05-07 |
| Myostatin Irna Compositions And Methods Of Use Thereof App 20200138847 - Jadhav; Vasant R. ; et al. | 2020-05-07 |
| Lipid Compositions App 20200138955 - Manoharan; Muthiah ; et al. | 2020-05-07 |
| Hepatitis D virus (HDV) iRNA compositions and methods of use thereof Grant 10,640,770 - Hinkle , et al. | 2020-05-05 |
| Modified double-stranded RNA agents Grant 10,612,024 - Maier , et al. | 2020-04-07 |
| Modified double-stranded RNA agents Grant 10,612,027 - Maier , et al. | 2020-04-07 |
| SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20200080085 - Sehgal; Alfica ; et al. | 2020-03-12 |
| APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20200080088 - Fitzgerald; Kevin ; et al. | 2020-03-12 |
| RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases Grant 10,570,391 - Rajeev , et al. Feb | 2020-02-25 |
| Monomers and oligonucleotides comprising cycloaddition adduct(s) Grant 10,550,386 - Manoharan , et al. Fe | 2020-02-04 |
| COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20200032259 - Fitzgerald; Kevin ; et al. | 2020-01-30 |
| Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20200017855 - Allerson; Charles ; et al. | 2020-01-16 |
| Hepatitis B virus (HBV) iRNA compositions and methods of use thereof Grant 10,513,703 - Hinkle , et al. Dec | 2019-12-24 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20190374646 - Maier; Martin ; et al. | 2019-12-12 |
| MODIFIED iRNA AGENTS App 20190345498 - MANOHARAN; Muthiah ; et al. | 2019-11-14 |
| Lipid compositions Grant 10,456,473 - Manoharan , et al. Oc | 2019-10-29 |
| SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20190316127 - Schlegel; Mark K. ; et al. | 2019-10-17 |
| Apolipoprotein C3 (APOC3) iRNA compositions and methods of use thereof Grant 10,407,679 - Fitzgerald , et al. Sept | 2019-09-10 |
| Therapeutic Compositions App 20190264207 - MANOHARAN; Muthiah ; et al. | 2019-08-29 |
| Oligonucleotide end caps Grant 10,385,337 - Manoharan , et al. A | 2019-08-20 |
| Modified Double-stranded Rna Agents App 20190241893 - MAIER; Martin ; et al. | 2019-08-08 |
| Modified Double-stranded Rna Agents App 20190241891 - Maier; Martin ; et al. | 2019-08-08 |
| Biodegradable lipids for the delivery of active agents Grant 10,369,226 - Maier , et al. | 2019-08-06 |
| Carbohydrate Conjugates As Delivery Agents For Oligonucleotides App 20190184018 - MANOHARAN; Muthiah ; et al. | 2019-06-20 |
| Novel Lipids And Compositions For The Delivery Of Therapeutics App 20190167800 - Manoharan; Muthiah ; et al. | 2019-06-06 |
| Carbohydrate Conjugated Rna Agents And Process For Their Preparation App 20190134206 - Nair; Jayaprakash K. ; et al. | 2019-05-09 |
| Therapeutic compositions Grant 10,273,477 - Manoharan , et al. | 2019-04-30 |
| Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 10,266,825 - Allerson , et al. | 2019-04-23 |
| Biodegradable lipids for the delivery of active agents Grant 10,266,484 - Manoharan , et al. | 2019-04-23 |
| Targeting Lipids App 20190099493 - Manoharan; Muthiah ; et al. | 2019-04-04 |
| Modified double-stranded RNA agents Grant 10,233,448 - Maier , et al. | 2019-03-19 |
| Chemical Modifications Of Monomers And Oligonucleotides With Cycloaddition App 20190048344 - Manoharan; Muthiah ; et al. | 2019-02-14 |
| HIGH DENSITY LIPOPROTEIN BINDING PROTEIN (HDLBP/VIGILIN) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20190038658 - Manoharan; Muthiah ; et al. | 2019-02-07 |
| MODIFIED RNAi AGENTS App 20190038768 - RAJEEV; Kallanthottathil G. ; et al. | 2019-02-07 |
| Compositions For Nucleic Acid Delivery App 20180369384 - Manoharan; Muthiah ; et al. | 2018-12-27 |
| Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes App 20180362978 - Bettencourt; Brian ; et al. | 2018-12-20 |
| SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20180346910 - Sehgal; Alfica ; et al. | 2018-12-06 |
| 5' phosphate mimics Grant 10,131,908 - Manoharan , et al. November 20, 2 | 2018-11-20 |
| iRNA AGENTS WITH BIOCLEAVABLE TETHERS App 20180327744 - MANOHARAN; Muthiah ; et al. | 2018-11-15 |
| Carbohydrate Conjugates As Delivery Agents For Oligonucleotides App 20180326070 - MANOHARAN; Muthiah ; et al. | 2018-11-15 |
| PCSK9 iRNA compositions and methods of use thereof Grant 10,125,369 - Borodovsky , et al. November 13, 2 | 2018-11-13 |
| iRNA agents with biocleavable tethers Grant 10,119,138 - Manoharan , et al. November 6, 2 | 2018-11-06 |
| RNAi agents modified at the 4'-C position Grant 10,119,136 - Manoharan , et al. November 6, 2 | 2018-11-06 |
| Lipids and compositions for the delivery of therapeutics Grant 10,117,941 - Manoharan , et al. November 6, 2 | 2018-11-06 |
| Carbohydrate conjugated RNA agents and process for their preparation Grant 10,086,081 - Nair , et al. October 2, 2 | 2018-10-02 |
| MODIFIED iRNA AGENTS App 20180258427 - MANOHARAN; Muthiah ; et al. | 2018-09-13 |
| Site-specific Delivery Of Nucleic Acids By Combining Targeting Ligands With Endosomolytic Components App 20180221494 - Manoharan; Muthiah ; et al. | 2018-08-09 |
| Methods And Compositions For Delivery Of Active Agents App 20180221510 - Manoharan; Muthiah ; et al. | 2018-08-09 |
| Multi-targeted Single Entity Conjugates App 20180208927 - JADHAV; Vasant ; et al. | 2018-07-26 |
| Serpina1 iRNA compositions and methods of use thereof Grant 10,030,244 - Sehgal , et al. July 24, 2 | 2018-07-24 |
| PEGylated lipids and their use for drug delivery Grant 9,999,673 - Rajeev , et al. June 19, 2 | 2018-06-19 |
| Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes Grant 9,970,006 - Bettencourt , et al. May 15, 2 | 2018-05-15 |
| Novel Lipids And Compositions For The Delivery Of Therapeutics App 20180125985 - Manoharan; Muthiah ; et al. | 2018-05-10 |
| Lipid Compositions App 20180104342 - Manoharan; Muthiah ; et al. | 2018-04-19 |
| Novel Lipids And Compositions For The Delivery Of Therapeutics App 20180092971 - Manoharan; Muthiah ; et al. | 2018-04-05 |
| Novel Lipids And Compositions For The Delivery Of Therapeutics App 20180064807 - Manoharan; Muthiah ; et al. | 2018-03-08 |
| Lipid Containing Formulations App 20180065918 - Manoharan; Muthiah ; et al. | 2018-03-08 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20180065920 - Manoharan; Muthiah ; et al. | 2018-03-08 |
| Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components Grant 9,895,448 - Manoharan , et al. February 20, 2 | 2018-02-20 |
| Novel Lipids And Compositions For The Delivery Of Therapeutics App 20180043009 - Manoharan; Muthiah ; et al. | 2018-02-15 |
| Carbohydrate conjugates as delivery agents for oligonucleotides Grant 9,867,882 - Manoharan , et al. January 16, 2 | 2018-01-16 |
| MODIFIED RNAi AGENTS App 20180008724 - RAJEEV; Kallanthottathil G. ; et al. | 2018-01-11 |
| Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20170369880 - Allerson; Charles ; et al. | 2017-12-28 |
| Reversir Tm Compounds App 20170369872 - JADHAV; Vasant ; et al. | 2017-12-28 |
| Complement component C5 iRNA compositions and methods of use thereof Grant 9,850,488 - Fitzgerald , et al. December 26, 2 | 2017-12-26 |
| HEPATITIS B VIRUS (HBV) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20170349900 - Hinkle; Gregory ; et al. | 2017-12-07 |
| HEPATITIS D VIRUS (HDV) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20170349901 - Hinkle; Gregory ; et al. | 2017-12-07 |
| Targeting lipids Grant 9,814,777 - Manoharan , et al. November 14, 2 | 2017-11-14 |
| Modified RNAi agents Grant 9,796,974 - Rajeev , et al. October 24, 2 | 2017-10-24 |
| Therapeutic Compositions App 20170283801 - MANOHARAN; Muthiah ; et al. | 2017-10-05 |
| Modified Double-stranded Rna Agents App 20170275626 - MAIER; Martin ; et al. | 2017-09-28 |
| Phosphorous-linked oligomeric compounds and their use in gene modulation Grant 9,771,578 - Baker , et al. September 26, 2 | 2017-09-26 |
| COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20170268005 - Fitzgerald; Kevin ; et al. | 2017-09-21 |
| Lipids and compositions for the delivery of therapeutics Grant 9,764,036 - Manoharan , et al. September 19, 2 | 2017-09-19 |
| APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20170260527 - Fitzgerald; Kevin ; et al. | 2017-09-14 |
| 5'-end derivatives Grant 9,725,479 - Manoharan , et al. August 8, 2 | 2017-08-08 |
| Modified RNAi agents Grant 9,708,607 - Rajeev , et al. July 18, 2 | 2017-07-18 |
| Lipids and compositions for the delivery of therapeutics Grant 9,707,292 - Manoharan , et al. July 18, 2 | 2017-07-18 |
| Therapeutic compositions Grant 9,708,615 - Manoharan , et al. July 18, 2 | 2017-07-18 |
| Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 9,708,610 - Allerson , et al. July 18, 2 | 2017-07-18 |
| Di-aliphatic substituted pegylated lipids Grant 9,701,623 - Manoharan , et al. July 11, 2 | 2017-07-11 |
| Complement component C5 iRNA compositions and methods of use thereof Grant 9,701,963 - Fitzgerald , et al. July 11, 2 | 2017-07-11 |
| Lipid compositions Grant 9,694,077 - Manoharan , et al. July 4, 2 | 2017-07-04 |
| Compositions for nucleic acid delivery Grant 9,687,550 - Manoharan , et al. June 27, 2 | 2017-06-27 |
| Biodegradable lipids for the delivery of active agents Grant 9,682,922 - Manoharan , et al. June 20, 2 | 2017-06-20 |
| Lipids and compositions for the delivery of therapeutics Grant 9,682,139 - Manoharan , et al. June 20, 2 | 2017-06-20 |
| Lipid Formulation App 20170143631 - Chen; Jianxin ; et al. | 2017-05-25 |
| SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20170114342 - Sehgal; Alfica ; et al. | 2017-04-27 |
| Monomers And Oligonucleotides Comprising Cycloaddition Adduct(s) App 20170107513 - MANOHARAN; Muthiah ; et al. | 2017-04-20 |
| Oligonucleotide End Caps App 20170107511 - MANOHARAN; Muthiah ; et al. | 2017-04-20 |
| Serapina1 iRNA compositions and methods of use thereof Grant 9,574,192 - Sehgal , et al. February 21, 2 | 2017-02-21 |
| Methods And Compositions For Detecting Anti-drug Antibodies App 20170044591 - Rajeev; Kallanthottathil G. ; et al. | 2017-02-16 |
| Monomers and oligonucleotides comprising cycloaddition adduct(s) Grant 9,566,340 - Manoharan , et al. February 14, 2 | 2017-02-14 |
| RNAi AGENTS MODIFIED AT THE 4'-C POSITION App 20170029815 - MANOHARAN; Muthiah ; et al. | 2017-02-02 |
| Oligonucleotide-ligand Conjugates And Process For Their Preparation App 20160376585 - MANOHARAN; Muthiah ; et al. | 2016-12-29 |
| iRNA AGENTS WITH BIOCLEAVABLE TETHERS App 20160376591 - MANOHARAN; Muthiah ; et al. | 2016-12-29 |
| Targeting Lipids App 20160375137 - Manoharan; Muthiah ; et al. | 2016-12-29 |
| Site-specific Delivery Of Nucleic Acids By Combining Targeting Ligands With Endosomolytic Components App 20160367687 - Manoharan; Muthiah ; et al. | 2016-12-22 |
| Rnai Agents, Compositions And Methods Of Use Thereof For Treating Transthyretin (ttr) Associated Diseases App 20160355817 - Rajeev; Kallanthottathil G. ; et al. | 2016-12-08 |
| Oligonucleotide end caps Grant 9,512,164 - Manoharan , et al. December 6, 2 | 2016-12-06 |
| Nucleic Acid Chemical Modifications App 20160348110 - MANOHARAN; Muthiah ; et al. | 2016-12-01 |
| Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes App 20160333342 - Bettencourt; Brian ; et al. | 2016-11-17 |
| Methods And Compositions For Delivery Of Nucleic Acids App 20160317676 - Hope; Michael J. ; et al. | 2016-11-03 |
| iRNA agents with biocleavable tethers Grant 9,476,045 - Manoharan , et al. October 25, 2 | 2016-10-25 |
| Compositions And Methods For Inhibiting Expression Of Mylip/idol Gene App 20160298122 - Bettencourt; Brian ; et al. | 2016-10-13 |
| Nucleic acid chemical modifications Grant 9,453,043 - Manoharan , et al. September 27, 2 | 2016-09-27 |
| Ligand-conjugated monomers Grant 9,453,222 - Manoharan , et al. September 27, 2 | 2016-09-27 |
| MODIFIED iRNA AGENTS App 20160264968 - MANOHARAN; Muthiah ; et al. | 2016-09-15 |
| SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20160257954 - Akinc; Akin ; et al. | 2016-09-08 |
| Methods And Compositions For Delivery Of Active Agents App 20160250354 - Manoharan; Muthiah ; et al. | 2016-09-01 |
| COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20160244763 - Fitzgerald; Kevin ; et al. | 2016-08-25 |
| Novel Lipids And Compositions For The Delivery Of Therapeutics App 20160213785 - Manoharan; Muthiah ; et al. | 2016-07-28 |
| RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases Grant 9,399,775 - Rajeev , et al. July 26, 2 | 2016-07-26 |
| Modified iRNA agents Grant 9,394,540 - Manoharan , et al. July 19, 2 | 2016-07-19 |
| Lipid formulations Grant 9,394,234 - Chen , et al. July 19, 2 | 2016-07-19 |
| Novel Lipids And Compositions For The Delivery Of Therapeutics App 20160199485 - Manoharan; Muthiah ; et al. | 2016-07-14 |
| Serpinc1 iRNA compositions and methods of use thereof Grant 9,376,680 - Akinc , et al. June 28, 2 | 2016-06-28 |
| Carbohydrate conjugates as delivery agents for oligonucleotides Grant 9,370,582 - Manoharan , et al. June 21, 2 | 2016-06-21 |
| Carbohydrate conjugates as delivery agents for oligonucleotides Grant 9,370,581 - Manoharan , et al. June 21, 2 | 2016-06-21 |
| Carbohydrate conjugates as delivery agents for oligonucleotides Grant 9,352,048 - Manoharan , et al. May 31, 2 | 2016-05-31 |
| Site specific delivery of nucleic acids by combining targeting ligands with endosomolytic components Grant 9,345,780 - Manoharan , et al. May 24, 2 | 2016-05-24 |
| COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20160108401 - Fitzgerald; Kevin ; et al. | 2016-04-21 |
| Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes Grant 9,315,813 - Bettencourt , et al. April 19, 2 | 2016-04-19 |
| Monomers And Oligonucleotides Comprising Cycloaddition Adduct(s) App 20160101189 - MANOHARAN; Muthiah ; et al. | 2016-04-14 |
| Modified iRNA agents Grant 9,290,760 - Rajeev , et al. March 22, 2 | 2016-03-22 |
| Phosphorous-linked Oligomeric Compounds And Their Use In Gene Modulation App 20160076031 - Baker; Brenda F. ; et al. | 2016-03-17 |
| Therapeutic Compositions App 20160076040 - MANOHARAN; Muthiah ; et al. | 2016-03-17 |
| Compositions Comprising Alternating 2'-modified Nucleosides For Use In Gene Modulation App 20160053261 - Allerson; Charles ; et al. | 2016-02-25 |
| Carbohydrate Conjugates As Delivery Agents For Oligonucleotides App 20160051691 - MANOHARAN; Muthiah ; et al. | 2016-02-25 |
| Methods and compositions for delivery of active agents Grant 9,254,327 - Manoharan , et al. February 9, 2 | 2016-02-09 |
| Complement component C5 iRNA compositions and methods of use thereof Grant 9,249,415 - Fitzgerald , et al. February 2, 2 | 2016-02-02 |
| Chimeric Oligomeric Compounds And Their Use In Gene Modulation App 20160017324 - Baker; Brenda F. ; et al. | 2016-01-21 |
| SERPINC1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20160017330 - Akinc; Akin ; et al. | 2016-01-21 |
| PCSK9 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20160017335 - Borodovsky; Anna ; et al. | 2016-01-21 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20160009637 - MANOHARAN; Muthiah ; et al. | 2016-01-14 |
| Lipids and compositions for the delivery of therapeutics Grant 9,220,683 - Manoharan , et al. December 29, 2 | 2015-12-29 |
| Therapeutic compositions Grant 9,222,091 - Manoharan , et al. December 29, 2 | 2015-12-29 |
| Monomers and oligonucleotides comprising cycloaddition adduct(s) Grant 9,198,972 - Manoharan , et al. December 1, 2 | 2015-12-01 |
| Compositions and methods for inhibiting expression of Mylip/Idol gene Grant 9,198,983 - Bettencourt , et al. December 1, 2 | 2015-12-01 |
| Lipids and compositions for the delivery of therapeutics Grant 9,186,325 - Manoharan , et al. November 17, 2 | 2015-11-17 |
| Modified 5' diphosphate nucleosides and oligomeric compounds prepared therefrom Grant 9,156,873 - Prakash , et al. October 13, 2 | 2015-10-13 |
| Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 9,150,605 - Allerson , et al. October 6, 2 | 2015-10-06 |
| Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 9,150,606 - Allerson , et al. October 6, 2 | 2015-10-06 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20150273068 - MAIER; Martin ; et al. | 2015-10-01 |
| Novel Lipids And Compositions For The Delivery Of Therapeutics App 20150265708 - Manoharan; Muthiah ; et al. | 2015-09-24 |
| Methods and compositions for prevention or treatment of RSV infection Grant 9,127,277 - Vaishnaw , et al. September 8, 2 | 2015-09-08 |
| COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF App 20150247143 - Fitzgerald; Kevin ; et al. | 2015-09-03 |
| Treatment Of Neurological Disorders App 20150224213 - SAH; Dinah W.Y. ; et al. | 2015-08-13 |
| 2' and 5' modified monomers and oligonucleotides Grant 9,102,938 - Rajeev , et al. August 11, 2 | 2015-08-11 |
| Nucleic Acid Chemical Modifications App 20150210733 - MANOHARAN; Muthiah ; et al. | 2015-07-30 |
| Chemical Modifications Of Monomers And Oligonucleotides With Cycloaddition App 20150203847 - MANOHARAN; Muthiah ; et al. | 2015-07-23 |
| Di-aliphatic Substituted Pegylated Lipids App 20150203446 - Manoharan; Muthiah ; et al. | 2015-07-23 |
| Carbohydrate Conjugated Rna Agents And Process For Their Preparation App 20150196655 - Nair; Jayaprakash K. ; et al. | 2015-07-16 |
| MODIFIED RNAi AGENTS App 20150197746 - Rajeev; Kallanthottathil G. ; et al. | 2015-07-16 |
| Ligand-conjugated Monomers App 20150191726 - MANOHARAN; Muthiah ; et al. | 2015-07-09 |
| Lipid Compositions App 20150190515 - Manoharan; Muthiah ; et al. | 2015-07-09 |
| Biodegradable lipids for the delivery of active agents Grant 9,061,063 - Maier , et al. June 23, 2 | 2015-06-23 |
| Lipid Formulations App 20150166465 - Chen; Jianxin ; et al. | 2015-06-18 |
| Process for triphosphate oligonucleotide synthesis Grant 9,035,041 - Zlatev , et al. May 19, 2 | 2015-05-19 |
| Carbohydrate Conjugates as Delivery Agents for Oligonucleotides App 20150119444 - MANOHARAN; Muthiah ; et al. | 2015-04-30 |
| Carbohydrate Conjugates as Delivery Agents for Oligonucleotides App 20150119445 - MANOHARAN; Muthiah ; et al. | 2015-04-30 |
| Biodegradable lipids for the delivery of active agents Grant 9,012,498 - Manoharan , et al. April 21, 2 | 2015-04-21 |
| Lipids and compositions for the delivery of therapeutics Grant 8,999,351 - Manoharan , et al. April 7, 2 | 2015-04-07 |
| Nuclease resistant double-stranded ribonucleic acid Grant 8,993,746 - Vornlocher , et al. March 31, 2 | 2015-03-31 |
| 5' Phosphate Mimics App 20150080457 - MANOHARAN; Muthiah ; et al. | 2015-03-19 |
| iRNA AGENTS WITH BIOCLEAVABLE TETHERS App 20150073133 - MANOHARAN; Muthiah ; et al. | 2015-03-12 |
| Nucleic acid chemical modifications Grant 8,975,389 - Manoharan , et al. March 10, 2 | 2015-03-10 |
| Chemical modifications of monomers and oligonucleotides with cycloaddition Grant 8,962,580 - Manoharan , et al. February 24, 2 | 2015-02-24 |
| Ligand-conjugated monomers Grant 8,957,223 - Manoharan , et al. February 17, 2 | 2015-02-17 |
| Treatment of neurological disorders Grant 8,957,038 - Sah , et al. February 17, 2 | 2015-02-17 |
| Carbohydrate Conjugates as Delivery Agents for Oligonucleotides App 20150011615 - MANOHARAN; Muthiah ; et al. | 2015-01-08 |
| RNAi MODULATION OF RSV AND THERAPEUTIC USES THEREOF App 20150011612 - Meyers; Rachel ; et al. | 2015-01-08 |
| iRNA Agents Targeting VEGF App 20150011608 - de Fougerolles; Antonin ; et al. | 2015-01-08 |
| 5' phosphate mimics Grant 8,927,513 - Manoharan , et al. January 6, 2 | 2015-01-06 |
| Lipid compositions Grant 8,883,202 - Manoharan , et al. November 11, 2 | 2014-11-11 |
| Rnai Agents, Compositions And Methods Of Use Thereof For Treating Transthyretin (ttr) Associated Diseases App 20140315835 - Rajeev; Kallanthottathil G. ; et al. | 2014-10-23 |
| MODIDIFED iRNA AGENTS App 20140316124 - MANOHARAN; Muthiah ; et al. | 2014-10-23 |
| iRNA agents with biocleavable tethers Grant 8,865,677 - Manoharan , et al. October 21, 2 | 2014-10-21 |
| Lipids For The Delivery Of Active Agents App 20140308304 - Manoharan; Muthiah ; et al. | 2014-10-16 |
| Therapeutic Compositions App 20140309411 - MANOHARAN; Muthiah ; et al. | 2014-10-16 |
| RNAi modulation of RSV and therapeutic uses thereof Grant 8,859,750 - Meyers , et al. October 14, 2 | 2014-10-14 |
| MODIFIED RNAi AGENTS App 20140288158 - Rajeev; Kallanthottathil G. ; et al. | 2014-09-25 |
| Site Specific Delivery Of Nucleic Acids By Combining Targeting Ligands With Endosomolytic Components App 20140256785 - Manoharan; Muthiah ; et al. | 2014-09-11 |
| Carbohydrate conjugates as delivery agents for oligonucleotides Grant 8,828,956 - Manoharan , et al. September 9, 2 | 2014-09-09 |
| Therapeutic compositions Grant 8,809,516 - Manoharan , et al. August 19, 2 | 2014-08-19 |
| Lipid formulation Grant 8,802,644 - Chen , et al. August 12, 2 | 2014-08-12 |
| Modified iRNA agents Grant 8,796,436 - Manoharan , et al. August 5, 2 | 2014-08-05 |
| Pegylated Lipids And Their Use For Drug Delivery App 20140200257 - Rajeev; Kallanthottathil G ; et al. | 2014-07-17 |
| Targeting Lipids App 20140179761 - Manoharan; Muthiah ; et al. | 2014-06-26 |
| Therapeutic compositions Grant 8,754,201 - Manoharan , et al. June 17, 2 | 2014-06-17 |
| Lipids and compositions for the delivery of therapeutics Grant 8,722,082 - Manoharan , et al. May 13, 2 | 2014-05-13 |
| Lipid Containing Formulations App 20140121393 - Manoharan; Muthiah ; et al. | 2014-05-01 |
| Compositions and Methods for Inhibition of Expression of Apolipoprotein C-III (APOC3) Genes App 20140113957 - Bettencourt; Brian ; et al. | 2014-04-24 |
| Compositions And Methods For Enhancing Production Of A Biological Product App 20140099666 - Rossomando; Anthony ; et al. | 2014-04-10 |
| Compositions and methods for non-parenteral delivery of oligonucleotides Grant 8,691,785 - Teng , et al. April 8, 2 | 2014-04-08 |
| Chemically Modified Oligonucleotides For Use In Modulating Micro Rna And Uses Thereof App 20140073684 - Stoffel; Markus ; et al. | 2014-03-13 |
| Folate Conjugates App 20140045919 - Manoharan; Muthiah ; et al. | 2014-02-13 |
| Lipid containing formulations Grant 8,642,076 - Manoharan , et al. February 4, 2 | 2014-02-04 |
| Cell-based Bioprocessing App 20140004565 - Rossomando; Anthony ; et al. | 2014-01-02 |
| Compositions For Nucleic Acid Delivery App 20130338210 - Manoharan; Muthiah ; et al. | 2013-12-19 |
| Compositions comprising alternating 2'-modified nucleosides for use in gene modulation Grant 8,604,183 - Allerson , et al. December 10, 2 | 2013-12-10 |
| 5'-end Derivatives App 20130323836 - Manoharan; Muthiah ; et al. | 2013-12-05 |
| Methods And Compositions For Delivery Of Active Agents App 20130323269 - Manoharan; Muthiah ; et al. | 2013-12-05 |
| MODIFIED iRNA AGENTS App 20130317080 - Rajeev; Kallanthottathil G. ; et al. | 2013-11-28 |
| Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components Grant 8,575,123 - Manoharan , et al. November 5, 2 | 2013-11-05 |
| iRNA AGENTS WITH BIOCLEAVABLE TETHERS App 20130281685 - MANOHARAN; Muthiah ; et al. | 2013-10-24 |
| Compositions And Methods For Non-parenteral Delivery Of Oligonucleotides App 20130274309 - Teng; Ching-Leou ; et al. | 2013-10-17 |
| Methods And Compositions For Treating Neurological Disease App 20130261166 - Manoharan; Muthiah ; et al. | 2013-10-03 |
| Conformationally Restricted Dinucleotide Monomers And Oligonucleotides App 20130260460 - Lackey; Jeremy ; et al. | 2013-10-03 |
| Supports for oligomer synthesis Grant 8,541,599 - Ravikumar , et al. September 24, 2 | 2013-09-24 |
| Chemically modified oligonucleotides for use in modulation micro RNA and uses thereof Grant 8,541,385 - Stoffel , et al. September 24, 2 | 2013-09-24 |
| Multifunctional Copolymers For Nucleic Acid Delivery App 20130236968 - Manoharan; Muthiah ; et al. | 2013-09-12 |
| MODIFIED iRNA AGENTS App 20130211063 - MANOHARAN; Muthiah ; et al. | 2013-08-15 |
| Folate conjugates Grant 8,507,455 - Manoharan , et al. August 13, 2 | 2013-08-13 |
| Modified iRNA agents Grant 8,507,661 - Manoharan , et al. August 13, 2 | 2013-08-13 |
| 2' And 5' Modified Monomers And Oligonucleotides App 20130203836 - Rajeev; Kallanthottathil G. ; et al. | 2013-08-08 |
| Methods And Compositions For Delivery Of Active Agents App 20130202652 - Manoharan; Muthiah ; et al. | 2013-08-08 |
| Biodegradable Lipids For The Delivery Of Active Agents App 20130195920 - MAIER; Martin ; et al. | 2013-08-01 |
| ENHANCEMENT OF siRNA SILENCING ACTIVITY USING UNIVERSAL BASES OR MISMATCHES IN THE SENSE STRAND App 20130196434 - MAIER; Martin ; et al. | 2013-08-01 |
| Ligand-conjugated Monomers App 20130184328 - MANOHARAN; Muthiah ; et al. | 2013-07-18 |
| Carbohydrate Conjugates As Delivery Agents For Oligonucleotides App 20130178512 - MANOHARAN; Muthiah ; et al. | 2013-07-11 |
| Methods And Compositions For Prevention Or Treatment Of RSV Infection App 20130165499 - Vaishnaw; Akshay ; et al. | 2013-06-27 |
| Cell-based Methods And Reagents App 20130164329 - Rossomando; Anthony ; et al. | 2013-06-27 |
| Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety Grant 8,470,988 - Manoharan , et al. June 25, 2 | 2013-06-25 |
| Lipid Formulated Single Stranded Rna App 20130156845 - Manoharan; Muthiah ; et al. | 2013-06-20 |
| Nuclease Resistant Double-stranded Ribonucleic Acid App 20130150570 - VORNLOCHER; Hans-Peter ; et al. | 2013-06-13 |
| Therapeutic Compositions App 20130144048 - MANOHARAN; Muthiah ; et al. | 2013-06-06 |
| Carbohydrate conjugates as delivery agents for oligonucleotides Grant 8,450,467 - Manoharan , et al. May 28, 2 | 2013-05-28 |
| Methods And Compositions For Delivery Of Active Agents App 20130129785 - Manoharan; Muthiah ; et al. | 2013-05-23 |
| Oligonucleotides Comprising Acyclic And Abasic Nucleosides And Analogs App 20130130378 - Manoharan; Muthiah ; et al. | 2013-05-23 |
| Therapeutic compositions Grant 8,445,665 - Manoharan , et al. May 21, 2 | 2013-05-21 |
| Compositions And Methods For Inhibiting Expression Of Mylip/idol Gene App 20130123332 - Bettencourt; Brian ; et al. | 2013-05-16 |
| Modified 5' Diphosphate Nucleosides And Oligomeric Compounds Prepared Therefrom App 20130109850 - Prakash; Thazha P. ; et al. | 2013-05-02 |
| Process for desilylation of oligonucleotides Grant 8,431,693 - Manoharan , et al. April 30, 2 | 2013-04-30 |
| iRNA agents with biocleavable tethers Grant 8,426,377 - Manoharan , et al. April 23, 2 | 2013-04-23 |
| Therapeutic compositions Grant 8,420,799 - Manoharan April 16, 2 | 2013-04-16 |
| Methods and compositions for prevention or treatment of RSV infection Grant 8,410,073 - Vaishnaw , et al. April 2, 2 | 2013-04-02 |
| Ligand-conjugated monomers Grant 8,404,862 - Manoharan , et al. March 26, 2 | 2013-03-26 |
| Monomers And Oligonucleotides Comprising Cycloaddition Adduct(s) App 20130053334 - Manoharan; Muthiah ; et al. | 2013-02-28 |
| Compositions and methods for non-parenteral delivery of oligonucleotides Grant 8,377,897 - Teng , et al. February 19, 2 | 2013-02-19 |
| Modified iRNA agents Grant 8,344,125 - Manoharan , et al. January 1, 2 | 2013-01-01 |
| Nuclease resistant double-stranded ribonucleic acid Grant 8,334,373 - Vornlocher , et al. December 18, 2 | 2012-12-18 |
| Compositions and methods for delivering RNAI using lipoproteins Grant 8,324,366 - Akinc , et al. December 4, 2 | 2012-12-04 |
| iRNA agents targeting VEGF Grant 8,293,719 - De Fougerolles , et al. October 23, 2 | 2012-10-23 |
| Lipid formulation Grant 8,158,601 - Chen , et al. April 17, 2 | 2012-04-17 |
| RNAi modulation of RSV and therapeutic uses thereof Grant 8,158,773 - Myers , et al. April 17, 2 | 2012-04-17 |
| Supports for oligomer synthesis Grant 8,153,725 - Ravikumar , et al. April 10, 2 | 2012-04-10 |
| Therapeutic compositions Grant 8,110,674 - Manoharan , et al. February 7, 2 | 2012-02-07 |
| Carbohydrate conjugates as delivery agents for oligonucleotides Grant 8,106,022 - Manoharan , et al. January 31, 2 | 2012-01-31 |
| Processes and reagents for desilylation of oligonucleotides Grant 8,063,198 - Manoharan , et al. November 22, 2 | 2011-11-22 |
| Processes and reagents for sulfurization of oligonucleotides Grant 8,058,448 - Manoharan , et al. November 15, 2 | 2011-11-15 |
| IRNA agents targeting CCR5 expressing cells and uses thereof Grant 8,034,921 - Manoharan , et al. October 11, 2 | 2011-10-11 |
| Lipid containing formulations Grant 8,034,376 - Manoharan , et al. October 11, 2 | 2011-10-11 |
| Chemically modified oligonucleotides Grant 8,017,763 - Manoharan , et al. September 13, 2 | 2011-09-13 |
| Modified iRNA agents Grant 8,017,762 - Manoharan , et al. September 13, 2 | 2011-09-13 |
| Oligonucleotides comprising a non-phosphate backbone linkage Grant 8,013,136 - Manoharan , et al. September 6, 2 | 2011-09-06 |
| iRNA agents targeting VEGF Grant 7,947,659 - de Fougerolles , et al. May 24, 2 | 2011-05-24 |
uspto.report is an independent third-party trademark research tool that is not affiliated, endorsed, or sponsored by the United States Patent and Trademark Office (USPTO) or any other governmental organization. The information provided by uspto.report is based on publicly available data at the time of writing and is intended for informational purposes only.
While we strive to provide accurate and up-to-date information, we do not guarantee the accuracy, completeness, reliability, or suitability of the information displayed on this site. The use of this site is at your own risk. Any reliance you place on such information is therefore strictly at your own risk.
All official trademark data, including owner information, should be verified by visiting the official USPTO website at www.uspto.gov. This site is not intended to replace professional legal advice and should not be used as a substitute for consulting with a legal professional who is knowledgeable about trademark law.
| 