Patent | Date |
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Disease therapy by inducing immune response to Trop-2 expressing cells Grant 10,662,252 - Chang , et al. | 2020-05-26 |
Murine, chimeric, humanized or human anti-TNF-alpha antibodies Grant 10,385,139 - Goldenberg , et al. A | 2019-08-20 |
T-cell redirecting bispecific antibodies for treatment of disease Grant 10,308,688 - Chang , et al. | 2019-06-04 |
Combination Therapy For Inducing Immune Response To Disease App 20190142939 - Chang; Chien-Hsing ;   et al. | 2019-05-16 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 10,280,220 - Govindan | 2019-05-07 |
Combination therapy for inducing immune response to disease Grant 10,245,321 - Chang , et al. | 2019-04-02 |
T-cell redirecting bispecific antibodies for treatment of disease Grant 10,239,938 - Chang , et al. | 2019-03-26 |
T-cell redirecting bispecific antibodies for treatment of disease Grant 10,183,992 - Chang , et al. Ja | 2019-01-22 |
Combination therapy with T-cell redirecting bispecific antibodies and checkpoint inhibitors Grant 10,131,712 - Rossi , et al. November 20, 2 | 2018-11-20 |
Combination therapy for inducing immune response to disease Grant 10,111,954 - Chang , et al. October 30, 2 | 2018-10-30 |
Interferon lambda-antibody complexes Grant 10,022,427 - Chang , et al. July 17, 2 | 2018-07-17 |
Bispecific Antibodies that Neutralize TNF-alpha and IL-6: Novel Therapeutic Agents for Autoimmune Disease App 20180186898 - Goldenberg; David M. ;   et al. | 2018-07-05 |
Disease Therapy By Inducing Immune Response To Trop-2 Expressing Cells App 20180118846 - Chang; Chien-Hsing ;   et al. | 2018-05-03 |
Tetrameric cytokines with improved biological activity Grant 9,931,413 - Chang , et al. April 3, 2 | 2018-04-03 |
Murine, chimeric, humanized or human anti-IL-6 antibodies Grant 9,932,413 - Goldenberg , et al. April 3, 2 | 2018-04-03 |
Multivalent Antibody Complexes Targeting IGF-1R Show Potent Toxicity Against Solid Tumors App 20180079816 - Chang; Chien-Hsing ;   et al. | 2018-03-22 |
Disease therapy by inducing immune response to Trop-2 expressing cells Grant 9,879,088 - Chang , et al. January 30, 2 | 2018-01-30 |
PEGylation by the dock and lock (DNL) technique Grant 9,872,920 - Chang , et al. January 23, 2 | 2018-01-23 |
Multivalent antibody complexes targeting IGF-1R show potent toxicity against solid tumors Grant 9,862,770 - Chang , et al. January 9, 2 | 2018-01-09 |
Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy Grant 9,839,689 - Chang , et al. December 12, 2 | 2017-12-12 |
Combination Therapy For Inducing Immune Response To Disease App 20170281767 - Chang; Chien-Hsing ;   et al. | 2017-10-05 |
Bispecific Antibodies That Neutralize Both Tnf-alpha And Il-6: Novel Therapeutic Agent For Autoimmune Disease App 20170283511 - Goldenberg; David M. ;   et al. | 2017-10-05 |
Combination Therapy With T-cell Redirecting Bispecific Antibodies And Checkpoint Inhibitors App 20170275375 - Rossi; Edmund A. ;   et al. | 2017-09-28 |
T-Cell Redirecting Bispecific Antibodies for Treatment of Disease App 20170247417 - Chang; Chien-Hsing ;   et al. | 2017-08-31 |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases Grant 9,737,617 - Chang , et al. August 22, 2 | 2017-08-22 |
Disease Therapy By Inducing Immune Response To Trop-2 Expressing Cells App 20170226219 - Chang; Chien-Hsing ;   et al. | 2017-08-10 |
Combination therapy for inducing immune response to disease Grant 9,682,143 - Chang , et al. June 20, 2 | 2017-06-20 |
Modular Method to Prepare Tetrameric Cytokines with Improved Pharmacokinetics by the Dock-and-Lock (DNL) Technology App 20170166651 - Chang; Chien-Hsing ;   et al. | 2017-06-15 |
Disease therapy by inducing immune response to Trop-2 expressing cells Grant 9,670,286 - Chang , et al. June 6, 2 | 2017-06-06 |
Methods for Generating Stably Linked Complexes Composed of Homodimers, Homotetramers or Dimers of Dimers and Uses App 20170121692 - Chang; Chien-Hsing ;   et al. | 2017-05-04 |
Dock-and-Lock (DNL) Complexes for Disease Therapy Grant 9,623,115 - Chang , et al. April 18, 2 | 2017-04-18 |
Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock Grant 9,617,531 - Chang , et al. April 11, 2 | 2017-04-11 |
Dock-and-Lock (DNL) Complexes for Therapeutic and Diagnostic Use App 20170088635 - Chang; Chien-Hsing ;   et al. | 2017-03-30 |
Tetrameric Cytokines with Improved Biological Activity App 20170056516 - Chang; Chien-Hsing ;   et al. | 2017-03-02 |
T-Cell Redirecting Bispecific Antibodies for Treatment of Disease App 20170022274 - Chang; Chien-Hsing ;   et al. | 2017-01-26 |
Combination Therapy For Inducing Immune Response To Disease App 20170021017 - Chang; Chien-Hsing ;   et al. | 2017-01-26 |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use Grant 9,550,838 - Chang , et al. January 24, 2 | 2017-01-24 |
Stably tethered structures of defined compositions with multiple functions or binding specificities Grant 9,540,435 - Chang , et al. January 10, 2 | 2017-01-10 |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses Grant 9,540,618 - Chang , et al. January 10, 2 | 2017-01-10 |
Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity App 20160375108 - Chang; Chien-Hsing ;   et al. | 2016-12-29 |
Dock-and-Lock (DNL) Vaccines for Cancer Therapy App 20160361405 - Chang; Chien-Hsing ;   et al. | 2016-12-15 |
PEGylation by the Dock and Lock (DNL) Technique App 20160361435 - Chang; Chien-Hsing ;   et al. | 2016-12-15 |
Multimeric Complexes with Improved in Vivo Stability, Pharmacokinetics and Efficacy App 20160340443 - Rossi; Edmund A. ;   et al. | 2016-11-24 |
Tetrameric cytokines with improved biological activity Grant 9,498,542 - Chang , et al. November 22, 2 | 2016-11-22 |
Dock-and-Lock (DNL) Complexes for delivery of interference RNA Grant 9,492,561 - Chang , et al. November 15, 2 | 2016-11-15 |
Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity Grant 9,481,878 - Chang , et al. November 1, 2 | 2016-11-01 |
Bispecific Antibodies That Neutralize Both Tnf-alpha And Il-6: Novel Therapeutic Agent For Autoimmune Disease App 20160311931 - Goldenberg; David M. ;   et al. | 2016-10-27 |
Dock-and-lock (DNL) vaccines for cancer therapy Grant 9,457,072 - Chang , et al. October 4, 2 | 2016-10-04 |
PEGylation by the dock and lock (DNL) technique Grant 9,457,100 - Chang , et al. October 4, 2 | 2016-10-04 |
Multimeric complexes with improved in vivo stability, pharmacokinetics and efficacy Grant 9,446,123 - Rossi , et al. September 20, 2 | 2016-09-20 |
Disease Therapy By Inducing Immune Response To Trop-2 Expressing Cells App 20160264678 - Chang; Chien-Hsing ;   et al. | 2016-09-15 |
Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity App 20160257947 - Chang; Chien-Hsing ;   et al. | 2016-09-08 |
Combination Therapy With Anti-CD74 and Anti-CD20 Antibodies Provides Enhanced Toxicity to B-Cell Diseases App 20160243226 - Chang; Chien-Hsing ;   et al. | 2016-08-25 |
Bispecific antibodies that neutralize both TNF-.alpha. and IL-6: novel therapeutic agent for autoimmune disease Grant 9,416,197 - Goldenberg , et al. August 16, 2 | 2016-08-16 |
Disease therapy by inducing immune response to Trop-2 expressing cells Grant 9,382,329 - Chang , et al. July 5, 2 | 2016-07-05 |
T-Cell Redirecting Bispecific Antibodies for Treatment of Disease App 20160176980 - Chang; Chien-Hsing ;   et al. | 2016-06-23 |
T-Cell Redirecting Bispecific Antibodies for Treatment of Disease App 20160176968 - Chang; Chien-Hsing ;   et al. | 2016-06-23 |
Combination therapy with anti-CD74 and anti-CD20 antibodies provides enhanced toxicity to B-cell diseases Grant 9,359,443 - Chang , et al. June 7, 2 | 2016-06-07 |
Interferon Lambda-antibody Complexes App 20160129086 - Chang; Chien-Hsing ;   et al. | 2016-05-12 |
T-cell redirecting bispecific antibodies for treatment of disease Grant 9,315,567 - Chang , et al. April 19, 2 | 2016-04-19 |
Dock-and-Lock (DNL) Constructs for Human Immunodeficiency Virus (HIV) Therapy App 20160089449 - Chang; Chien-Hsing ;   et al. | 2016-03-31 |
Interferon lambada-antibody complexes Grant 9,272,029 - Chang , et al. March 1, 2 | 2016-03-01 |
Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy Grant 9,248,184 - Chang , et al. February 2, 2 | 2016-02-02 |
Methods and Compositions for Generating Bioactive Assemblies of Increased Complexity and Uses App 20150374846 - Chang; Chien-Hsing ;   et al. | 2015-12-31 |
Methods and compositions for generating bioactive assemblies of increased complexity and uses Grant 9,169,470 - Chang , et al. October 27, 2 | 2015-10-27 |
Combination Therapy For Inducing Immune Response To Disease App 20150231241 - Chang; Chien-Hsing ;   et al. | 2015-08-20 |
Disease Therapy By Inducing Immune Response To Trop-2 Expressing Cells App 20150132217 - Chang; Chien-Hsing ;   et al. | 2015-05-14 |
Bispecific Antibodies That Neutralize Both Tnf-alpha And Il-6: Novel Therapeutic Agent For Autoimmune Disease App 20150125450 - Goldenberg; David M. ;   et al. | 2015-05-07 |
Methods for Generating Stably Linked Complexes Composed of Homodimers, Homotetramers or Dimers of Dimers and Uses App 20150056680 - Chang; Chien-Hsing ;   et al. | 2015-02-26 |
Stably Tethered Structures of Defined Compositions with Multiple Functions or Binding Specificities App 20150050715 - Chang; Chien-Hsing ;   et al. | 2015-02-19 |
Combination Therapy With Anti-CD74 Antibodies Provides Enhanced Toxicity to Malignancies, Autoimmune Disease and Other Diseases App 20150037283 - Chang; Chien-Hsing ;   et al. | 2015-02-05 |
Multivalent Antibody Complexes Targeting IGF-1R Show Potent Toxicity Against Solid Tumors App 20150024459 - Chang; Chien-Hsing ;   et al. | 2015-01-22 |
Dock-and-Lock (DNL) Complexes for Therapeutic and Diagnostic Use App 20150024458 - Chang; Chien-Hsing ;   et al. | 2015-01-22 |
Multiple Signaling Pathways Induced by Hexavalent, Monospecific and Bispecific Antibodies for Enhanced Toxicity to B-Cell Lymphomas and Other Diseases App 20150023870 - Chang; Chien-Hsing ;   et al. | 2015-01-22 |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses Grant 8,932,593 - Chang , et al. January 13, 2 | 2015-01-13 |
Methods and Compositions for Generating Bioactive Assemblies of Increased Complexity and Uses App 20150010982 - Chang; Chien-Hsing ;   et al. | 2015-01-08 |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, autoimmune disease and other diseases Grant 8,906,378 - Chang , et al. December 9, 2 | 2014-12-09 |
Stably tethered structures of defined compositions with multiple functions or binding specificities Grant 8,906,377 - Chang , et al. December 9, 2 | 2014-12-09 |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use Grant 8,883,160 - Chang , et al. November 11, 2 | 2014-11-11 |
Multivalent antibody complexes targeting IGF-1R show potent toxicity against solid tumors Grant 8,883,162 - Chang , et al. November 11, 2 | 2014-11-11 |
Multiple signaling pathways induced by hexvalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases Grant 8,871,216 - Chang , et al. October 28, 2 | 2014-10-28 |
Methods and compositions for generating bioactive assemblies of increased complexity and uses Grant 8,865,176 - Chang , et al. October 21, 2 | 2014-10-21 |
Nucleic acids encoding polyvalent protein complexes Grant 8,829,175 - Rossi , et al. September 9, 2 | 2014-09-09 |
Tetrameric Cytokines with Improved Biological Activity App 20140161766 - Chang; Chien-Hsing ;   et al. | 2014-06-12 |
Combination Therapy For Inducing Immune Response To Disease App 20140099254 - Chang; Chien-Hsing ;   et al. | 2014-04-10 |
T-Cell Redirecting Bispecific Antibodies for Treatment of Disease App 20140050660 - Chang; Chien-Hsing ;   et al. | 2014-02-20 |
Novel Strategies for Improved Cancer Vaccines App 20140045242 - Chang; Chien-Hsing ;   et al. | 2014-02-13 |
Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity App 20140038261 - Chang; Chien-Hsing ;   et al. | 2014-02-06 |
Multimeric Complexes with Improved in Vivo Stability, Pharmacokinetics and Efficacy App 20130323204 - Rossi; Edmund A. ;   et al. | 2013-12-05 |
Tetrameric cytokines with improved biological activity Grant 8,597,659 - Chang , et al. December 3, 2 | 2013-12-03 |
Combination Therapy With Anti-CD74 Antibodies Provides Enhanced Toxicity to Malignancies, Autoimmune Disease and Other Diseases App 20130295005 - Chang; Chien-Hsing ;   et al. | 2013-11-07 |
Dock-and-Lock (DNL) Complexes for Delivery of Interference RNA App 20130289244 - Chang; Chien-Hsing ;   et al. | 2013-10-31 |
Dock-and-Lock (DNL) Constructs for Human Immunodeficiency Virus (HIV) Therapy App 20130280250 - Chang; Chien-Hsing ;   et al. | 2013-10-24 |
Strategies for improved cancer vaccines Grant 8,562,988 - Chang , et al. October 22, 2 | 2013-10-22 |
Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity Grant 8,551,480 - Chang , et al. October 8, 2 | 2013-10-08 |
Dimeric Alpha Interferon PEGylated Site-Specifically Shows Enhanced and Prolonged Efficacy in Vivo App 20130217091 - Chang; Chien-Hsing ;   et al. | 2013-08-22 |
Dock-and-lock (DNL) complexes for delivery of interference RNA Grant 8,491,914 - Chang , et al. July 23, 2 | 2013-07-23 |
PEGylation by the Dock and Lock (DNL) Technique App 20130177532 - Chang; Chien-Hsing ;   et al. | 2013-07-11 |
Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy Grant 8,481,041 - Chang , et al. July 9, 2 | 2013-07-09 |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, Autoimmune disease and other diseases Grant 8,475,794 - Chang , et al. July 2, 2 | 2013-07-02 |
Methods and Compositions for Generating Bioactive Assemblies of Increased Complexity and Uses App 20130164816 - Chang; Chien-Hsing ;   et al. | 2013-06-27 |
Targeting Interferon-lambda With Antibodies Potently Enhances Anti-tumor And Anti-viral Activities App 20130136718 - Chang; Chien-Hsing ;   et al. | 2013-05-30 |
Dimeric alpha interferon PEGylated site-specifically shows enhanced and prolonged efficacy in VIVO Grant 8,435,540 - Chang , et al. May 7, 2 | 2013-05-07 |
Modular Method to Prepare Tetrameric Cytokines with Improved Pharmacokinetics by the Dock-and-Lock (DNL) Technology App 20130109073 - Chang; Chien-Hsing ;   et al. | 2013-05-02 |
Multivalent Antibody Complexes Targeting IGF-1R Show Potent Toxicity Against Solid Tumors App 20130095033 - Chang; Chien-Hsing ;   et al. | 2013-04-18 |
Multiple Signaling Pathways Induced by Hexavalent, Monospecific and Bispecific Antibodies for Enhanced Toxicity to B-Cell Lymphomas and Other Diseases App 20130078183 - Chang; Chien-Hsing ;   et al. | 2013-03-28 |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases Grant 8,349,332 - Chang , et al. January 8, 2 | 2013-01-08 |
Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity App 20120276100 - Chang; Chien-Hsing ;   et al. | 2012-11-01 |
Multivalent Immunoglobulin-Based Bioactive Assemblies App 20120276608 - Chang; Chien-Hsing ;   et al. | 2012-11-01 |
Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology Grant 8,282,934 - Chang , et al. October 9, 2 | 2012-10-09 |
PEGylation by the dock and lock (DNL) technique Grant 8,277,817 - Chang , et al. October 2, 2 | 2012-10-02 |
Design and Construction of Novel Multivalent Antibodies App 20120237442 - Rossi; Edmund A. ;   et al. | 2012-09-20 |
Dimeric Alpha Interferon PEGylated Site-Specifically Shows Enhanced and Prolonged Efficacy in Vivo App 20120225032 - Chang; Chien-Hsing ;   et al. | 2012-09-06 |
Methods and compositions for generating bioactive assemblies of increased complexity and uses Grant 8,246,960 - Chang , et al. August 21, 2 | 2012-08-21 |
Methods for Generating Stably Linked Complexes Composed of Homodimers, Homotetramers or Dimers of Dimers and Uses App 20120196346 - Chang; Chien-Hsing ;   et al. | 2012-08-02 |
Multivalent immunoglobulin-based bioactive assemblies Grant 8,211,440 - Chang , et al. July 3, 2 | 2012-07-03 |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses Grant 8,163,291 - Chang , et al. April 24, 2 | 2012-04-24 |
Stem Cell Targeting with Dock-and-Lock (DNL) Complexes App 20120093769 - Chang; Chien-Hsing ;   et al. | 2012-04-19 |
Dimeric alpha interferon PEGylated site-specifically shows enhanced and prolonged efficacy in vivo Grant 8,158,129 - Chang , et al. April 17, 2 | 2012-04-17 |
Dock-and-Lock (DNL) Constructs for Human Immunodeficiency Virus (HIV) Therapy App 20120082685 - Chang; Chien-Hsing ;   et al. | 2012-04-05 |
Tetrameric Cytokines with Improved Biological Activity App 20120009149 - Chang; Chien-Hsing ;   et al. | 2012-01-12 |
Modular Method to Prepare Tetrameric Cytokines with Improved Pharmacokinetics by the Dock-and-Lock (DNL) Technology App 20110318306 - Chang; Chien-Hsing ;   et al. | 2011-12-29 |
Dimeric Alpha Interferon PEGylated Site-Specifically Shows Enhanced and Prolonged Efficacy in Vivo App 20110300105 - Chang; Chien-Hsing ;   et al. | 2011-12-08 |
Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity App 20110274704 - Chang; Chien-Hsing ;   et al. | 2011-11-10 |
Tetrameric cytokines with improved biological activity Grant 8,034,352 - Chang , et al. October 11, 2 | 2011-10-11 |
PEGylation by the Dock and Lock (DNL) Technique App 20110236352 - Chang; Chien-Hsing ;   et al. | 2011-09-29 |
Dimeric alpha interferon pegylated site-specifically shows enhanced and prolonged efficacy in vivo Grant 8,003,111 - Chang , et al. August 23, 2 | 2011-08-23 |
Methods and Compositions for Generating Bioactive Assemblies of Increased Complexity and Uses App 20110195020 - Chang; Chien-Hsing ;   et al. | 2011-08-11 |
Dock-and-Lock (DNL) Vaccines for Cancer Therapy App 20110189083 - Chang; Chien-Hsing ;   et al. | 2011-08-04 |
PEGylation by the dock and lock (DNL) technique Grant 7,981,398 - Chang , et al. July 19, 2 | 2011-07-19 |
Dock-and-Lock (DNL) Complexes for Therapeutic and Diagnostic Use App 20110158905 - Goldenberg; David M. ;   et al. | 2011-06-30 |
Stably Tethered Structures of Defined Compositions with Multiple Functions or Binding Specificities App 20110143417 - Chang; Chien-Hsing ;   et al. | 2011-06-16 |
Dock-and-Lock (DNL) Complexes for Delivery of Interference RNA App 20110123436 - Chang; Chien-Hsing ;   et al. | 2011-05-26 |
Multivalent Immunoglobulin-Based Bioactive Assemblies App 20110110851 - Chang; Chien-Hsing ;   et al. | 2011-05-12 |
Methods and compositions for generating bioactive assemblies of increased complexity and uses Grant 7,906,121 - Chang , et al. March 15, 2 | 2011-03-15 |
Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (DNL) technology Grant 7,906,118 - Chang , et al. March 15, 2 | 2011-03-15 |
Dock-and-lock (DNL) vaccines for cancer therapy Grant 7,901,680 - Chang , et al. March 8, 2 | 2011-03-08 |
Bispecific Immunocytokine Dock-and-Lock (DNL) Complexes and Therapeutic Use Thereof App 20110020273 - Chang; Chien-Hsing ;   et al. | 2011-01-27 |
Stably tethered structures of defined compositions with multiple functions or binding specificities Grant 7,871,622 - Chang , et al. January 18, 2 | 2011-01-18 |
Methods for Generating Stably Linked Complexes Composed of Homodimers, Homotetramers or Dimers of Dimers and Uses App 20110008251 - Chang; Chien-Hsing ;   et al. | 2011-01-13 |
Multivalent immunoglobulin-based bioactive assemblies Grant 7,858,070 - Chang , et al. December 28, 2 | 2010-12-28 |
PEGylation by the Dock and Lock (DNL) Technique App 20100261885 - Chang; Chien-Hsing ;   et al. | 2010-10-14 |
Dimeric Alpha Interferon PEGylated Site-Specifically Shows Enhanced and Prolonged Efficacy in Vivo App 20100221210 - Chang; Chien-Hsing ;   et al. | 2010-09-02 |
Tetrameric Cytokines with Improved Biological Activity App 20100189689 - Chang; Chien-Hsing ;   et al. | 2010-07-29 |
Dock-and-Lock (DNL) Vaccines for Cancer Therapy App 20100068137 - Chang; Chien-Hsing ;   et al. | 2010-03-18 |
PEGylation by the dock and lock (DNL) technique Grant 7,666,400 - Chang , et al. February 23, 2 | 2010-02-23 |
Multivalent Immunoglobulin-Based Bioactive Assemblies App 20090269277 - Chang; Chien-Hsing ;   et al. | 2009-10-29 |
Modular Method to Prepare Tetrameric Cytokines with Improved Pharmacokinetics by the Dock-and-Lock (DNL) Technology App 20090202487 - Chang; Chien-Hsing ;   et al. | 2009-08-13 |
Methods and Compositions for Generating Bioactive Assemblies of Increased Complexity and Uses App 20090202433 - Chang; Chien-Hsing ;   et al. | 2009-08-13 |
Stably Tethered Structures of Defined Compositions with Multiple Functions or Binding Specificities App 20090191225 - Chang; Chien-Hsing ;   et al. | 2009-07-30 |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses Grant 7,550,143 - Chang , et al. June 23, 2 | 2009-06-23 |
Methods and compositions for generating bioactive assemblies of increased complexity and uses Grant 7,534,866 - Chang , et al. May 19, 2 | 2009-05-19 |
Multivalent immunoglobulin-based bioactive assemblies Grant 7,527,787 - Chang , et al. May 5, 2 | 2009-05-05 |
Stably tethered structures of defined compositions with multiple functions or binding specificities Grant 7,521,056 - Chang , et al. April 21, 2 | 2009-04-21 |
Anti-KC4 humanized monoclonal antibody and cells that express the antibody Grant RE40,535 - Couto , et al. October 7, 2 | 2008-10-07 |
Polyvalent Protein Complex App 20080171855 - Rossi; Edmund A. ;   et al. | 2008-07-17 |
Multivalent immunoglobulin-based bioactive assemblies App 20070140966 - Chang; Chien-Hsing ;   et al. | 2007-06-21 |
Methods and compositions for generating bioactive assemblies of increased complexity and uses App 20070086942 - Chang; Chien Hsing ;   et al. | 2007-04-19 |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses App 20060228357 - Chang; Chien Hsing ;   et al. | 2006-10-12 |
Stably tethered structures of defined compositions with multiple functions or binding specificities App 20060228300 - Chang; Chien Hsing ;   et al. | 2006-10-12 |