| Patent | Date |
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Potent Mucosal Immune Response Induced By Modified Immunomodulatory Oligonucleotides
App 20110123540 - Wang; Daqing ; et al. | 2011-05-26 |
Immunostimulatory Oligonucleotide Multimers
App 20080193437 - Agrawal; Sudhir ; et al. | 2008-08-14 |
Immunostimulatory oligonucleotide multimers
App 20070179103 - Agrawal; Sudhir ; et al. | 2007-08-02 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
App 20070173469 - Agrawal; Sudhir ; et al. | 2007-07-26 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides
App 20060287261 - Agrawal; Sudhir ; et al. | 2006-12-21 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
App 20060287262 - Agrawal; Sudhir ; et al. | 2006-12-21 |
Synergisitic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy
App 20060217328 - Kandimalla; Ekambar R. ; et al. | 2006-09-28 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides
App 20060211641 - Agrawal; Sudhir ; et al. | 2006-09-21 |
Synergistic inhibition of VEGF and modulation of the immune response
App 20060105979 - Agrawal; Sudhir ; et al. | 2006-05-18 |
Immunostimulatory oligonucleotide multimers
App 20060094680 - Agrawal; Sudhir ; et al. | 2006-05-04 |
Immunostimulatory oligonucleotide multimers
App 20060094681 - Agrawal; Sudhir ; et al. | 2006-05-04 |
Synergistic stimulation of the immune system using immunostimulatory oligonucleotides and/or immunomer compounds in conjunction with cytokines and/or chemotherapeutic agents or radiation therapy
App 20060074040 - Kandimalla; Ekambar R. ; et al. | 2006-04-06 |
Immunostimulatory oligonucleotide multimers
App 20060025365 - Agrawal; Sudhir ; et al. | 2006-02-02 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides
App 20060019918 - Agrawal; Sudhir ; et al. | 2006-01-26 |
Immunostimulatory oligonucleotide multimers
App 20060019919 - Agrawal; Sudhir ; et al. | 2006-01-26 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
App 20060019909 - Agrawal; Sudhir ; et al. | 2006-01-26 |
Immunostimulatory oligonucleotide multimers
App 20060014713 - Agrawal; Sudhir ; et al. | 2006-01-19 |
Oligonucleotides specific for hepatitis B virus
Grant 6,984,729 - Frank , et al. January 10, 2 | 2006-01-10 |
Enhanced activity of HIV vaccine using a second generation immunomodulatory oligonucleotide
App 20050266015 - Clerici, Mario ; et al. | 2005-12-01 |
Potent mucosal immune response induced by modified immunomodulatory oligonucleotides
App 20050222072 - Wang, Daqing ; et al. | 2005-10-06 |
MDM2-specific antisense oligonucleotides
Grant 6,946,447 - Chen , et al. September 20, 2 | 2005-09-20 |
Method of down-regulating gene expression
Grant 6,936,593 - Agrawal , et al. August 30, 2 | 2005-08-30 |
Modulation of immunostimulatory properties by small oligonucleotide-based compounds
App 20050130918 - Agrawal, Sudhir ; et al. | 2005-06-16 |
Hybridization-based fluorescence assay
App 20050089915 - Kandimalla, Ekambar R. ; et al. | 2005-04-28 |
Modified protein kinase a-specific oligonucleotides and methods of their use
App 20050054600 - Agrawal, Sudhir | 2005-03-10 |
Synergistic treatment of cancer using immunomers in conjunction with therapeutic agents
App 20050009773 - Kandimalla, Ekambar R. ; et al. | 2005-01-13 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
Grant 6,815,429 - Agrawal November 9, 2 | 2004-11-09 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides
App 20040198685 - Agrawal, Sudhir ; et al. | 2004-10-07 |
Short immunomodulatory oligonucleotides
App 20040156825 - Agrawal, Sudhir ; et al. | 2004-08-12 |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
App 20040097719 - Agrawal, Sudhir ; et al. | 2004-05-20 |
Method of down-regulating gene expression
App 20040033980 - Agrawal, Sudhir ; et al. | 2004-02-19 |
Use of cyclodextrins to modulate gene expression with reduced immunostimulatory response
Grant 6,667,293 - Zhao , et al. December 23, 2 | 2003-12-23 |
Modified VEGF Oligonucleotides for Inhibition of tumor growth
Grant 6,649,596 - Smyth , et al. November 18, 2 | 2003-11-18 |
Method of down-regulating gene expression
Grant 6,645,943 - Agrawal , et al. November 11, 2 | 2003-11-11 |
Inhibition of infectious agents by exogenous oligonucleotides
App 20030191078 - Goodchild, John ; et al. | 2003-10-09 |
Inhibition of infectious agents by exogenous oligonucleotides
App 20030186911 - Goodchild, John ; et al. | 2003-10-02 |
Modified protein kinase A-specific oligonucleotides and methods of their use
Grant 6,624,293 - Agrawal September 23, 2 | 2003-09-23 |
Method of down-regulating gene expression
Grant 6,608,035 - Agrawal , et al. August 19, 2 | 2003-08-19 |
Building blocks with carbamate internucleoside linkages and oligonucleotides derived therefrom
Grant 6,605,708 - Habus , et al. August 12, 2 | 2003-08-12 |
Antisense oligonucleotides and methods to induce tumor cell death
App 20030125287 - Kandimalla, Ekambar R. ; et al. | 2003-07-03 |
Hyperstructure-forming carriers
App 20030109479 - Agrawal, Sudhir | 2003-06-12 |
Oligonucleotides specific for the marORAB operon
App 20030032612 - Levy, Stuart B. ; et al. | 2003-02-13 |
Branched oligonucleotides as pathogen-inhibitory agents
Grant 6,489,464 - Agrawal , et al. December 3, 2 | 2002-12-03 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides
Grant 6,476,000 - Agrawal November 5, 2 | 2002-11-05 |
HPV-specific oligonucleotides
Grant 6,458,940 - Roberts , et al. October 1, 2 | 2002-10-01 |
Oligonucleotide mediated specific cytokine induction and reduction of tumor growth in a mammal
Grant 6,426,334 - Agrawal , et al. July 30, 2 | 2002-07-30 |
Pseudo-cyclic oligonucleobases
Grant 6,383,752 - Agrawal , et al. May 7, 2 | 2002-05-07 |
Cooperative oligonucleotides
Grant 6,372,427 - Kandimalla , et al. April 16, 2 | 2002-04-16 |
Hybrid oligonucleotide phosphorothioates
Grant 6,346,614 - Metelev , et al. February 12, 2 | 2002-02-12 |
Oligonucleotides active against drug-resistant bacteria
Grant 6,335,436 - Rapaport , et al. January 1, 2 | 2002-01-01 |
Primary phosphoramidate internucleoside linkages and oligonucleotides containing the same
Grant 6,140,482 - Iyer , et al. October 31, 2 | 2000-10-31 |
Reagents and process for synthesis of oligonucleotides containing phosphorodithioate internucleoside linkages
Grant 6,117,992 - Iyer September 12, 2 | 2000-09-12 |
Antisense olignucleotides having tumorigenicity-inhibiting activity
Grant 6,054,439 - Szyf , et al. April 25, 2 | 2000-04-25 |
MDM2-specific antisense oligonucleotides
Grant 6,013,786 - Chen , et al. January 11, 2 | 2000-01-11 |
Inverted chimeric oligonucleotides
Grant 5,973,136 - Agrawal October 26, 1 | 1999-10-26 |
Method of modulating gene expression with reduced immunostimulatory response
Grant 5,968,909 - Agrawal , et al. October 19, 1 | 1999-10-19 |
Synthesis of oligonucleotides containing alkylphosphonate internucleoside linkages
Grant 5,962,674 - Iyer , et al. October 5, 1 | 1999-10-05 |
Process for making oligonucleotides containing o- and s- methylphosphotriester internucleoside linkages
Grant 5,955,599 - Iyer , et al. September 21, 1 | 1999-09-21 |
Antisense oligonucleotide alkylphosphonothioates and arylphospohonothioates
Grant 5,929,226 - Padmapriya , et al. July 27, 1 | 1999-07-27 |
Antisense oligonucleotides having tumorigenicity-inhibiting activity
Grant 5,919,772 - Szyf , et al. July 6, 1 | 1999-07-06 |
Affinity-based purification of oligonucleotides using soluble multimeric oligonucleotides
Grant 5,912,332 - Agrawal , et al. June 15, 1 | 1999-06-15 |
Mixed backbone antisense oligonucleotides containing 2'-5'-ribonucleotide- and 3'-5'-deoxyribonucleotides segments
Grant 5,886,165 - Kandimalla , et al. March 23, 1 | 1999-03-23 |
Oligonucleotides having modified CpG dinucleosides
Grant 5,856,462 - Agrawal January 5, 1 | 1999-01-05 |
Inhibition of neovascularization using vegf-specific oligonucleotides
Grant 5,814,620 - Robinson , et al. September 29, 1 | 1998-09-29 |
Detritylation of DMT-oligonucleotides using cationic ion-exchange resin
Grant 5,808,042 - Iyer , et al. September 15, 1 | 1998-09-15 |
Apparatus and process for multi stage solid phase synthesis of long chained organic molecules
Grant 5,807,525 - Allen , et al. September 15, 1 | 1998-09-15 |
Inhibition of neovascularization using VEGF-specific oligonucleotides
Grant 5,801,156 - Robinson , et al. September 1, 1 | 1998-09-01 |
CAPL-specific oligonucleotides and method of inhibiting metastatic cancer
Grant 5,789,248 - Fodstad , et al. August 4, 1 | 1998-08-04 |
Inverted chimeric and hybrid oligonucleotides
Grant 5,773,601 - Agrawal June 30, 1 | 1998-06-30 |
Methods and compounds for the stereoselective enrichment of oligonucleotide diastereomers and oligonucleotides thereby produced
Grant 5,750,674 - Iyer , et al. May 12, 1 | 1998-05-12 |
Integrated oligonucleotides
Grant 5,739,308 - Kandimalla , et al. April 14, 1 | 1998-04-14 |
Method for synthesizing 2'-O-substituted pyrimidine nucleosides
Grant 5,739,314 - Roy , et al. April 14, 1 | 1998-04-14 |
Inhibition of neovasularization using VEGF-specific oligonucleotides
Grant 5,731,294 - Robinson , et al. March 24, 1 | 1998-03-24 |
Inhibition of neovascularization using VEGF-specific oligonucleotides
Grant 5,710,136 - Robinson , et al. January 20, 1 | 1998-01-20 |
Methods for H-phosphonate synthesis of mono- and oligonucleotides
Grant 5,705,629 - Bhongle January 6, 1 | 1998-01-06 |
Triplex-forming antisense oligonucleotides having abasic linkers targeting nucleic acids comprising mixed sequences of purines and pyrimidines
Grant 5,693,773 - Kandimalla , et al. December 2, 1 | 1997-12-02 |
Cyclodextrin cellular delivery system for oligonucleotides
Grant 5,691,316 - Agrawal , et al. November 25, 1 | 1997-11-25 |
Therapeutic anti-HIV anti-viral oligonucleotides and pharmaceutical formulations thereof
Grant 5,684,147 - Agrawal , et al. November 4, 1 | 1997-11-04 |
Method of using ribozyme analogs having rigid, non-nucleotidic molecular linkers
Grant 5,679,555 - Goodchild , et al. October 21, 1 | 1997-10-21 |
Passivated polymer supports for nucleic acid synthesis
Grant 5,668,268 - Tang , et al. September 16, 1 | 1997-09-16 |
Inverted chimeric and hybrid oligonucleotides
Grant 5,652,356 - Agrawal July 29, 1 | 1997-07-29 |
Substrate useful for separating modified oligonucleotides
Grant 5,643,717 - Cohen , et al. * July 1, 1 | 1997-07-01 |
Modified VEGF oligonucleotides
Grant 5,641,756 - Robinson * June 24, 1 | 1997-06-24 |
Human VEGF-specific oligonucleotides
Grant 5,639,736 - Robinson June 17, 1 | 1997-06-17 |
Human VEGF-specific oligonucleotides
Grant 5,639,872 - Robinson June 17, 1 | 1997-06-17 |
Method of synthesizing radioisotopically labeled oligonucleotides by direct solid-phase 5' phosphitylation
Grant 5,631,361 - Tan , et al. May 20, 1 | 1997-05-20 |
5-pentenoyl moiety as a nucleoside-amino protecting group, 4-pentenoyl-protected nucleotide synthons, and related oligonucleotide syntheses
Grant 5,614,622 - Iyer , et al. March 25, 1 | 1997-03-25 |
Cyclodextrin cellular delivery system for oligonucleotides
Grant 5,605,890 - Agrawal , et al. February 25, 1 | 1997-02-25 |
Method of down-regulating gene expression
Grant 5,591,721 - Agrawal , et al. January 7, 1 | 1997-01-07 |
DNA methyltransferase antisense oligonucleotides
Grant 5,578,716 - Szyf , et al. November 26, 1 | 1996-11-26 |
Method for loading solid supports for nucleic acid synthesis
Grant 5,554,744 - Bhongle , et al. September 10, 1 | 1996-09-10 |
Stabilized ribozyme analogs
Grant 5,545,729 - Goodchild , et al. August 13, 1 | 1996-08-13 |
Method of sequencing [short] oligonucleotides
Grant 5,525,470 - Cohen , et al. June 11, 1 | 1996-06-11 |
Oligonucleotide multiple reporter precursors
Grant 5,510,475 - Agrawal , et al. April 23, 1 | 1996-04-23 |
Method for detecting charged oligonucleotides in biological fluids
Grant 5,506,103 - Cohen , et al. April 9, 1 | 1996-04-09 |
Method for sequencing synthetic oligonucleotides containing non-phosphodiester internucleotide linkages
Grant 5,403,709 - Agrawal , et al. April 4, 1 | 1995-04-04 |
Site-specific functionalization of oligodeoxynucleotides for non-radioactive labelling
Grant 5,321,131 - Agrawal , et al. June 14, 1 | 1994-06-14 |
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