Patent | Date |
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Synergistic effect of anti-trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors Grant 11,439,620 - Goldenberg , et al. September 13, 2 | 2022-09-13 |
Antibody-drug Conjugates And Uses Thereof App 20220054648 - Goldenberg; David M. ;   et al. | 2022-02-24 |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, Bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer Grant 11,253,606 - Goldenberg , et al. February 22, 2 | 2022-02-22 |
Efficacy Of Anti-trop-2-sn-38 Antibody Drug Conjugates For Therapy Of Tumors Relapsed/refractory To Checkpoint Inhibitors App 20210395385 - Govindan; Serengulam V. ;   et al. | 2021-12-23 |
Therapy For Metastatic Urothelial Cancer With The Antibody-drug Conjugate, Sacituzumab Govitecan (immu-132) App 20210393617 - Govindan; Serengulam V. ;   et al. | 2021-12-23 |
Efficacy of anti-Trop-2-SN-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors Grant 11,192,955 - Govindan , et al. December 7, 2 | 2021-12-07 |
Subcutaneous anti-HLA-DR monoclonal antibody for treatment of hematologic malignancies Grant 11,180,559 - Goldenberg , et al. November 23, 2 | 2021-11-23 |
Immunoconjugates With An Intracellularly-cleavable Linkage App 20210346511 - Goldenberg; David M. ;   et al. | 2021-11-11 |
Immunoconjugates with an intracellularly-cleavable linkage Grant RE48,751 - Govindan , et al. September 28, 2 | 2021-09-28 |
Antibody-drug conjugates and uses thereof Grant 11,116,846 - Goldenberg , et al. September 14, 2 | 2021-09-14 |
Neoadjuvant Use Of Antibody-drug Conjugates App 20210275682 - Goldenberg; David M. | 2021-09-09 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 11,077,201 - Govindan , et al. August 3, 2 | 2021-08-03 |
Antibody-drug conjugates and uses thereof Grant 11,052,156 - Goldenberg , et al. July 6, 2 | 2021-07-06 |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132) Grant 11,052,081 - Govindan , et al. July 6, 2 | 2021-07-06 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 11,020,489 - Govindan , et al. June 1, 2 | 2021-06-01 |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers Grant 10,988,539 - Goldenberg , et al. April 27, 2 | 2021-04-27 |
Combination of ABCG2 inhibitors with sacituzumab govitecan (IMMU-132) overcomes resistance to SN-38 in Trop-2 expressing cancers Grant 10,954,305 - Chang , et al. March 23, 2 | 2021-03-23 |
Antibody-drug Conjugates And Uses Thereof App 20210069343 - Goldenberg; David M. ;   et al. | 2021-03-11 |
Dosages Of Immunoconjugates Of Antibodies And Sn-38 For Improved Efficacy And Decreased Toxicity App 20210046185 - Govindan; Serengulam V. ;   et al. | 2021-02-18 |
Treatment of high Trop-2 expressing triple negative breast cancer (TNBC) with sacituzumab govitecan (IMMU-132) overcomes homologous recombination repair (HRR) rescue mediated by Rad51 Grant 10,918,734 - Cardillo , et al. February 16, 2 | 2021-02-16 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 10,918,721 - Govindan , et al. February 16, 2 | 2021-02-16 |
Antibody-drug conjugates and uses thereof Grant 10,849,986 - Goldenberg , et al. December 1, 2 | 2020-12-01 |
Subcutaneous administration of antibody-drug conjugates for cancer therapy Grant 10,799,597 - Goldenberg October 13, 2 | 2020-10-13 |
Dosages Of Immunoconjugates Of Antibodies And Sn-38 For Improved Efficacy And Decreased Toxicity App 20200316054 - Govindan; Serengulam V. ;   et al. | 2020-10-08 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20200276325 - Govindan; Serengulam V. ;   et al. | 2020-09-03 |
Antibody-SN-38 immunoconjugates with a CL2A linker Grant 10,751,420 - Govindan , et al. A | 2020-08-25 |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2 Grant 10,744,129 - Goldenberg , et al. A | 2020-08-18 |
Antibody-drug Conjugates And Uses Thereof App 20200246481 - Kind Code | 2020-08-06 |
Efficacy of anti-HLA-DR antibody drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers Grant 10,709,701 - Govindan , et al. | 2020-07-14 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 10,682,347 - Govindan , et al. | 2020-06-16 |
Anti-PD-1 checkpoint inhibitor antibodies that block binding of PD-L1 to PD-1 Grant 10,669,338 - Chang , et al. | 2020-06-02 |
Disease therapy by inducing immune response to Trop-2 expressing cells Grant 10,662,252 - Chang , et al. | 2020-05-26 |
Antibody-drug conjugates and uses thereof Grant 10,653,793 - Goldenberg , et al. | 2020-05-19 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20200121805 - Govindan; Serengulam V. ;   et al. | 2020-04-23 |
Antibody-drug Conjugates And Uses Thereof App 20200085968 - Goldenberg; David M. ;   et al. | 2020-03-19 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 10,561,738 - Govindan , et al. Feb | 2020-02-18 |
Therapy For Metastatic Urothelial Cancer With The Antibody-drug Conjugate, Sacituzumab Govitecan (immu-132) App 20190381032 - Govindan; Serengulam V. ;   et al. | 2019-12-19 |
Isolation, Detection, Diagnosis And/or Characterization Of Circulating Trop-2-positive Cancer Cells App 20190369103 - Goldenberg; David M. ;   et al. | 2019-12-05 |
Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells Grant 10,436,788 - Goldenberg , et al. O | 2019-10-08 |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132) Grant 10,413,539 - Govindan , et al. Sept | 2019-09-17 |
Murine, chimeric, humanized or human anti-TNF-alpha antibodies Grant 10,385,139 - Goldenberg , et al. A | 2019-08-20 |
Combination Of Abcg2 Inhibitors With Sacituzumab Govitecan (immu-132) Overcomes Resistance To Sn-38 In Trop-2 Expressing Cancers App 20190248917 - Chang; Chien-Hsing ;   et al. | 2019-08-15 |
Isolated nucleic acid encoding an anti-IGF-1R antibody Grant 10,377,829 - Chang , et al. A | 2019-08-13 |
Combining Anti-hla-dr Or Anti-trop-2 Antibodies With Microtubule Inhibitors, Parp Inhibitors, Bruton Kinase Inhibitors Or Phosph App 20190209703 - Goldenberg; David M. ;   et al. | 2019-07-11 |
Subcutaneous administration of anti-CD74 antibody for systemic lupus erythematosus Grant 10,322,176 - Goldenberg , et al. | 2019-06-18 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 10,322,193 - Govindan , et al. | 2019-06-18 |
Efficacy Of Anti-trop-2-sn-38 Antibody Drug Conjugates For Therapy Of Tumors Relapsed/refractory To Checkpoint Inhibitors App 20190177427 - Govindan; Serengulam V. ;   et al. | 2019-06-13 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20190167805 - Govindan; Serengulam V. ;   et al. | 2019-06-06 |
T-cell redirecting bispecific antibodies for treatment of disease Grant 10,308,688 - Chang , et al. | 2019-06-04 |
Combination Therapy For Inducing Immune Response To Disease App 20190142939 - Chang; Chien-Hsing ;   et al. | 2019-05-16 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 10,265,414 - Govindan , et al. | 2019-04-23 |
Efficacy of anti-trop-2-SN-38 antibody drug conjugates for therapy of tumors relapsed/refractory to checkpoint inhibitors Grant 10,266,605 - Govindan , et al. | 2019-04-23 |
Combination therapy for inducing immune response to disease Grant 10,245,321 - Chang , et al. | 2019-04-02 |
T-cell redirecting bispecific antibodies for treatment of disease Grant 10,239,938 - Chang , et al. | 2019-03-26 |
Synergistic Effect Of Anti-trop-2 Antibody-drug Conjugate In Combination Therapy For Triple-negative Breast Cancer When Used With Microtubule Inhibitors Or Parp Inhibitors App 20190083451 - Goldenberg; David M. ;   et al. | 2019-03-21 |
RS7 Antibodies App 20190083621 - Govindan; Serengulam V. ;   et al. | 2019-03-21 |
EFFICACY OF ANTI-HLA-DR ANTIBODY DRUG CONJUGATE IMMU-140 (hL243-CL2A-SN-38) IN HLA-DR POSITIVE CANCERS App 20190083487 - Govindan; Serengulam V. ;   et al. | 2019-03-21 |
Antibody-drug Conjugates And Uses Thereof App 20190070308 - Goldenberg; David M. ;   et al. | 2019-03-07 |
Humanized Anti-HLA-DR Antibodies App 20190071503 - Goldenberg; David M. ;   et al. | 2019-03-07 |
Efficacy of anti-HLA-DR antiboddy drug conjugate IMMU-140 (hL243-CL2A-SN-38) in HLA-DR positive cancers Grant 10,206,918 - Govindan , et al. Feb | 2019-02-19 |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors Grant 10,195,175 - Goldenberg , et al. Fe | 2019-02-05 |
Antibody-sn-38 Immunoconjugates With A Cl2a Linker App 20190030175 - Govindan; Serengulam V. ;   et al. | 2019-01-31 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20190022226 - Govindan; Serengulam V. ;   et al. | 2019-01-24 |
T-cell redirecting bispecific antibodies for treatment of disease Grant 10,183,992 - Chang , et al. Ja | 2019-01-22 |
Dosages Of Immunoconjugates Of Antibodies And Sn-38 For Improved Efficacy And Decreased Toxicity App 20190015405 - Govindan; Serengulam V. ;   et al. | 2019-01-17 |
RS7 antibodies Grant 10,179,171 - Govindan , et al. Ja | 2019-01-15 |
Humanized anti-HLA-DR antibodies Grant 10,174,114 - Goldenberg , et al. J | 2019-01-08 |
Nucleic acids encoding chimeric and humanized anti-histone antibodies Grant 10,160,801 - Chang , et al. Dec | 2018-12-25 |
Antibody-SN-38 immunoconjugates with a CL2A linker Grant 10,143,756 - Govindan , et al. De | 2018-12-04 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 10,137,196 - Govindan , et al. November 27, 2 | 2018-11-27 |
Combination therapy with T-cell redirecting bispecific antibodies and checkpoint inhibitors Grant 10,131,712 - Rossi , et al. November 20, 2 | 2018-11-20 |
Antibody-drug conjugates and uses thereof Grant 10,130,718 - Goldenberg , et al. November 20, 2 | 2018-11-20 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 10,130,626 - Govindan , et al. November 20, 2 | 2018-11-20 |
Combination Therapy With Anti-hla-dr Antibodies And Kinase Inhibitors In Hematopoietic Cancers App 20180327495 - Goldenberg; David M. ;   et al. | 2018-11-15 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20180318439 - Govindan; Serengulam V. ;   et al. | 2018-11-08 |
Combination therapy for inducing immune response to disease Grant 10,111,954 - Chang , et al. October 30, 2 | 2018-10-30 |
Chimeric and Humanized Anti-Histone Antibodies App 20180298089 - Chang; Chien-Hsing ;   et al. | 2018-10-18 |
Neoadjuvant Use Of Antibody-drug Conjugates App 20180296689 - Goldenberg; David M. | 2018-10-18 |
Subcutaneous Administration Of Antibody-drug Conjugates For Cancer Therapy App 20180280532 - Goldenberg; David M. | 2018-10-04 |
Treatment Of High Trop-2 Expressing Triple Negative Breast Cancer (tnbc) With Sacituzumab Govitecan (immu-132) Overcomes Homologous Recombination Repair (hrr) Rescue Mediated By Rad51 App 20180271992 - Cardillo; Thomas M. ;   et al. | 2018-09-27 |
RS7 Antibodies App 20180250406 - Govindan; Serengulam V. ;   et al. | 2018-09-06 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 10,064,957 - Govindan , et al. September 4, 2 | 2018-09-04 |
Combination therapy with anti-HLA-DR antibodies and kinase inhibitors in hematopoietic cancers Grant 10,058,621 - Goldenberg , et al. August 28, 2 | 2018-08-28 |
Chimeric and humanized anti-histone antibodies Grant 10,040,848 - Chang , et al. August 7, 2 | 2018-08-07 |
Antibody-SN-38 immunoconjugates with a CL2A linker Grant 10,034,950 - Govindan , et al. July 31, 2 | 2018-07-31 |
Interferon lambda-antibody complexes Grant 10,022,427 - Chang , et al. July 17, 2 | 2018-07-17 |
Therapy Of Small-cell Lung Cancer (sclc) With A Topoisomerase-i Inhibiting Antibody-drug Conjugate (adc) Targeting Trop-2 App 20180185351 - Goldenberg; David M. ;   et al. | 2018-07-05 |
Bispecific Antibodies that Neutralize TNF-alpha and IL-6: Novel Therapeutic Agents for Autoimmune Disease App 20180186898 - Goldenberg; David M. ;   et al. | 2018-07-05 |
Chimeric and Humanized Anti-Histone Antibodies App 20180171003 - Chang; Chien-Hsing ;   et al. | 2018-06-21 |
RS7 antibodies Grant 9,999,668 - Govindan , et al. June 19, 2 | 2018-06-19 |
Subcutaneous Anti-hla-dr Monoclonal Antibody For Treatment Of Hematologic Malignancies App 20180162945 - Goldenberg; David M. ;   et al. | 2018-06-14 |
Antibody-sn-38 Immunoconjugates With A Cl2a Linker App 20180161440 - Govindan; Serengulam V. ;   et al. | 2018-06-14 |
T20 constructs for anti-HIV (human immunodeficiency virus) therapy and/or vaccines Grant 9,993,547 - Stenler , et al. June 12, 2 | 2018-06-12 |
Isolation, Detection, Diagnosis And/or Characterization Of Circulating Trop-2-positive Cancer Cells App 20180149657 - Goldenberg; David M. ;   et al. | 2018-05-31 |
RS7 Antibodies App 20180133322 - Govindan; Serengulam V. ;   et al. | 2018-05-17 |
Stable compositions of high-concentration allotype-selected antibodies for small-volume administration Grant 9,963,516 - Zeng , et al. May 8, 2 | 2018-05-08 |
Therapeutic use of anti-CD22 antibodies for inducing trogocytosis Grant 9,963,507 - Chang , et al. May 8, 2 | 2018-05-08 |
Disease Therapy By Inducing Immune Response To Trop-2 Expressing Cells App 20180118846 - Chang; Chien-Hsing ;   et al. | 2018-05-03 |
Therapy For Metastatic Urothelial Cancer With The Antibody-drug Conjugate, Sacituzumab Govitecan (immu-132) App 20180110772 - Govindan; Serengulam V. ;   et al. | 2018-04-26 |
Humanized anti-CD22 antibody Grant 9,944,703 - Chang , et al. April 17, 2 | 2018-04-17 |
Murine, chimeric, humanized or human anti-IL-6 antibodies Grant 9,932,413 - Goldenberg , et al. April 3, 2 | 2018-04-03 |
Tetrameric cytokines with improved biological activity Grant 9,931,413 - Chang , et al. April 3, 2 | 2018-04-03 |
Antibody-SN-38 immunoconjugates with a CL2A linker Grant 9,931,417 - Govindan , et al. April 3, 2 | 2018-04-03 |
Antibody-sn-38 Immunoconjugates With A Cl2a Linker App 20180085469 - Govindan; Serengulam V. ;   et al. | 2018-03-29 |
Multivalent Antibody Complexes Targeting IGF-1R Show Potent Toxicity Against Solid Tumors App 20180079816 - Chang; Chien-Hsing ;   et al. | 2018-03-22 |
Methods for treating ischemic stroke using chimeric and humanized anti-histone antibodies Grant 9,920,116 - Chang , et al. March 20, 2 | 2018-03-20 |
Novel Anti-pd-1 Checkpoint Inhibitor Antibodies That Block Binding Of Pd-l1 To Pd-1 App 20180051085 - Chang; Chien-Hsing ;   et al. | 2018-02-22 |
Disease therapy by inducing immune response to Trop-2 expressing cells Grant 9,879,088 - Chang , et al. January 30, 2 | 2018-01-30 |
Chimeric and Humanized Anti-Histone Antibodies App 20180022796 - Chang; Chien-Hsing ;   et al. | 2018-01-25 |
PEGylation by the dock and lock (DNL) technique Grant 9,872,920 - Chang , et al. January 23, 2 | 2018-01-23 |
Multivalent antibody complexes targeting IGF-1R show potent toxicity against solid tumors Grant 9,862,770 - Chang , et al. January 9, 2 | 2018-01-09 |
Antibody-SN-38 immunoconjugates with a CL2A linker Grant 9,855,344 - Govindan , et al. January 2, 2 | 2018-01-02 |
RS7 antibodies Grant 9,849,176 - Govindan , et al. December 26, 2 | 2017-12-26 |
EFFICACY OF ANTI-HLA-DR ANTIBODY DRUG CONJUGATE IMMU-140 (hL243-CL2A-SN-38) IN HLA-DR POSITIVE CANCERS App 20170360770 - Govindan; Serengulam V. ;   et al. | 2017-12-21 |
Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy Grant 9,839,689 - Chang , et al. December 12, 2 | 2017-12-12 |
RS7 antibodies Grant 9,833,511 - Govindan , et al. December 5, 2 | 2017-12-05 |
Fusion Proteins Containing Recombinant Cytotoxic Rnases App 20170334996 - GOLDENBERG; David M. ;   et al. | 2017-11-23 |
Crosslinking Of Cd22 By Epratuzumab Triggers Bcr Signaling And Caspase-dependent Apoptosis In Hematopoietic Cancer Cells App 20170326238 - Chang; Chien-Hsing ;   et al. | 2017-11-16 |
Methods Of Treating Cancer With Antibodies That Target The Insulin-like Growth Factor Type I Receptor (igf-1r) App 20170320952 - Chang; Chien-Hsing ;   et al. | 2017-11-09 |
Methods for treating thrombosis using chimeric and humanized anti-histone antibodies Grant 9,809,646 - Chang , et al. November 7, 2 | 2017-11-07 |
Efficacy Of Anti-trop-2-sn-38 Antibody Drug Conjugates For Therapy Of Tumors Relapsed/refractory To Checkpoint Inhibitors App 20170313781 - Govindan; Serengulam V. ;   et al. | 2017-11-02 |
Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells Grant 9,797,907 - Goldenberg , et al. October 24, 2 | 2017-10-24 |
Bispecific Antibodies That Neutralize Both Tnf-alpha And Il-6: Novel Therapeutic Agent For Autoimmune Disease App 20170283511 - Goldenberg; David M. ;   et al. | 2017-10-05 |
Anti-trop-2 Antibody-drug Conjugates And Uses Thereof App 20170281791 - Govindan; Serengulam V. ;   et al. | 2017-10-05 |
Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules App 20170283442 - D'Souza; Christopher A. ;   et al. | 2017-10-05 |
Combination Therapy For Inducing Immune Response To Disease App 20170281767 - Chang; Chien-Hsing ;   et al. | 2017-10-05 |
RS7 Antibodies App 20170274079 - Govindan; Serengulam V. ;   et al. | 2017-09-28 |
Combining Anti-hla-dr Or Anti-trop-2 Antibodies With Microtubule Inhibitors, Parp Inhibitors, Bruton Kinase Inhibitors Or Phosphoinositide 3-kinase Inhibitors Significantly Improves Therapeutic Outcome In Cancer App 20170274093 - Goldenberg; David M. ;   et al. | 2017-09-28 |
Humanized Anti-cd22 Antibody App 20170275363 - Chang; Chien-Hsing ;   et al. | 2017-09-28 |
Combination Therapy With T-cell Redirecting Bispecific Antibodies And Checkpoint Inhibitors App 20170275375 - Rossi; Edmund A. ;   et al. | 2017-09-28 |
Anti-Trop-2 antibody-drug conjugates and uses thereof Grant 9,770,517 - Govindan , et al. September 26, 2 | 2017-09-26 |
Pro-drug Form (p2pdox) Of The Highly Potent 2-pyrrolinodoxorubicin Conjugated To Antibodies For Targeted Therapy Of Cancer App 20170266310 - Govindan; Serengulam V. ;   et al. | 2017-09-21 |
Subcutaneous Administration Of Anti-cd74 Antibody For Systemic Lupus Erythematosus And Autoimmune Disease App 20170266281 - Goldenberg; David M. ;   et al. | 2017-09-21 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20170266316 - Govindan; Serengulam V. ;   et al. | 2017-09-21 |
Stable Compositions of High-Concentration Allotype-Selected Antibodies for Small-Volume Administration App 20170260287 - Zeng; Li ;   et al. | 2017-09-14 |
Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells Grant 9,757,458 - Chang , et al. September 12, 2 | 2017-09-12 |
Class of monospecific and bispecific humanized antibodies that target the insulin-like growth factor type I receptor (IGF-1R) Grant 9,751,948 - Chang , et al. September 5, 2 | 2017-09-05 |
T20 Constructs For Anti-hiv (human Immunodeficiency Virus) Therapy And/or Vaccines App 20170246291 - Stenler; Sofia ;   et al. | 2017-08-31 |
T-Cell Redirecting Bispecific Antibodies for Treatment of Disease App 20170247417 - Chang; Chien-Hsing ;   et al. | 2017-08-31 |
Fusion proteins containing recombinant cytotoxic RNAses Grant 9,745,374 - Goldenberg , et al. August 29, 2 | 2017-08-29 |
RS7 antibodies Grant 9,745,380 - Govindan , et al. August 29, 2 | 2017-08-29 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20170239368 - Govindan; Serengulam V. ;   et al. | 2017-08-24 |
Multiple signaling pathways induced by hexavalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases Grant 9,737,617 - Chang , et al. August 22, 2 | 2017-08-22 |
Disease Therapy By Inducing Immune Response To Trop-2 Expressing Cells App 20170226219 - Chang; Chien-Hsing ;   et al. | 2017-08-10 |
Therapeutic Use of Anti-CD22 Antibodies for Inducing Trogocytosis App 20170226205 - Chang; Chien-Hsing ;   et al. | 2017-08-10 |
Combination Of Abcg2 Inhibitors With Sacituzumab Govitecan (immu-132) Overcomes Resistance To Sn-38 In Trop-2 Expressing Cancers App 20170224837 - Chang; Chien-Hsing ;   et al. | 2017-08-10 |
Methods for Treating Thrombosis Using Chimeric and Humanized Anti-Histone Antibodies App 20170218059 - Chang; Chien-Hsing ;   et al. | 2017-08-03 |
Combination Therapy With Anti-hla-dr Antibodies And Kinase Inhibitors In Hematopoietic Cancers App 20170216447 - Goldenberg; David M. ;   et al. | 2017-08-03 |
Synergistic Effect Of Anti-trop-2 Antibody-drug Conjugate In Combination Therapy For Triple-negative Breast Cancer When Used With Microtubule Inhibitors Or Parp Inhibitors App 20170209594 - Goldenberg; David M. ;   et al. | 2017-07-27 |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer Grant 9,707,302 - Goldenberg , et al. July 18, 2 | 2017-07-18 |
Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites Grant 9,707,300 - Govindan , et al. July 18, 2 | 2017-07-18 |
Humanized anti-CD22 antibody Grant 9,701,748 - Chang , et al. July 11, 2 | 2017-07-11 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 9,700,634 - Govindan , et al. July 11, 2 | 2017-07-11 |
Pro-drug form (P2PDox) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer Grant 9,694,088 - Govindan , et al. July 4, 2 | 2017-07-04 |
T20 constructs for anti-HIV (human immunodeficiency virus) therapy and/or vaccines Grant 9,687,547 - Stenler , et al. June 27, 2 | 2017-06-27 |
Methods and Compositions for Treatment of Human Immunodeficiency Virus Infection with Conjugated Antibodies or Antibody Fragments App 20170173167 - Goldenberg; David M. ;   et al. | 2017-06-22 |
Stable compositions of high-concentration allotype-selected antibodies for small-volume administration Grant 9,683,050 - Zeng , et al. June 20, 2 | 2017-06-20 |
Combination therapy for inducing immune response to disease Grant 9,682,143 - Chang , et al. June 20, 2 | 2017-06-20 |
Modular Method to Prepare Tetrameric Cytokines with Improved Pharmacokinetics by the Dock-and-Lock (DNL) Technology App 20170166651 - Chang; Chien-Hsing ;   et al. | 2017-06-15 |
Antibody-sn-38 Immunoconjugates With A Cl2a Linker App 20170165370 - Govindan; Serengulam V. ;   et al. | 2017-06-15 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 9,675,706 - Govindan , et al. June 13, 2 | 2017-06-13 |
Disease therapy by inducing immune response to Trop-2 expressing cells Grant 9,670,286 - Chang , et al. June 6, 2 | 2017-06-06 |
Camptothecin Conjugates of Anti-CD22 Antibodies for Treatment of B Cell Diseases App 20170151356 - GOVINDAN; Serengulam V. ;   et al. | 2017-06-01 |
Anti-CD19 Antibodies App 20170152315 - Hansen; Hans J. ;   et al. | 2017-06-01 |
Therapeutic use of anti-CD22 antibodies for inducing trogocytosis Grant 9,663,576 - Chang , et al. May 30, 2 | 2017-05-30 |
Methods for treating sepsis using chimeric and humanized anti-histone antibodies Grant 9,657,093 - Chang , et al. May 23, 2 | 2017-05-23 |
Anti-Pancreatic Cancer Antibodies App 20170137534 - Goldenberg; David M. ;   et al. | 2017-05-18 |
Methods for Generating Stably Linked Complexes Composed of Homodimers, Homotetramers or Dimers of Dimers and Uses App 20170121692 - Chang; Chien-Hsing ;   et al. | 2017-05-04 |
Antibody-SN-38 immunoconjugates with a CL2A linker Grant 9,629,926 - Govindan , et al. April 25, 2 | 2017-04-25 |
Dock-and-Lock (DNL) Complexes for Disease Therapy Grant 9,623,115 - Chang , et al. April 18, 2 | 2017-04-18 |
Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock Grant 9,617,531 - Chang , et al. April 11, 2 | 2017-04-11 |
Antibody-Based Depletion of Antigen-Presenting Cells and Dendritic Cells App 20170088619 - Chang; Chien-Hsing ;   et al. | 2017-03-30 |
Dock-and-Lock (DNL) Complexes for Therapeutic and Diagnostic Use App 20170088635 - Chang; Chien-Hsing ;   et al. | 2017-03-30 |
Anti-CD19 antibodies Grant 9,605,071 - Hansen , et al. March 28, 2 | 2017-03-28 |
Anti-pancreatic cancer antibodies Grant 9,599,619 - Goldenberg , et al. March 21, 2 | 2017-03-21 |
Humanized Anti-HLA-DR Antibodies App 20170066828 - Goldenberg; David M. ;   et al. | 2017-03-09 |
Tetrameric Cytokines with Improved Biological Activity App 20170056516 - Chang; Chien-Hsing ;   et al. | 2017-03-02 |
Detection of Early-Stage Pancreatic Adenocarcinoma App 20170035908 - Gold; David V. ;   et al. | 2017-02-09 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20170028081 - Govindan; Serengulam V. ;   et al. | 2017-02-02 |
T-Cell Redirecting Bispecific Antibodies for Treatment of Disease App 20170022274 - Chang; Chien-Hsing ;   et al. | 2017-01-26 |
Combination Therapy For Inducing Immune Response To Disease App 20170021017 - Chang; Chien-Hsing ;   et al. | 2017-01-26 |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use Grant 9,550,838 - Chang , et al. January 24, 2 | 2017-01-24 |
Antibody-drug Conjugates And Uses Thereof App 20170014527 - Goldenberg; David M. ;   et al. | 2017-01-19 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20170014403 - Govindan; Serengulam V. ;   et al. | 2017-01-19 |
METHODS OF IMAGING WITH Ga-68 LABELED MOLECULES App 20170007727 - Goldenberg; David M. | 2017-01-12 |
Stably tethered structures of defined compositions with multiple functions or binding specificities Grant 9,540,435 - Chang , et al. January 10, 2 | 2017-01-10 |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses Grant 9,540,618 - Chang , et al. January 10, 2 | 2017-01-10 |
Pro-drug Form (p2pdox) Of The Highly Potent 2-pyrrolinodoxorubicin Conjugated To Antibodies For Targeted Therapy Of Cancer App 20170000896 - Govindan; Serengulam V. ;   et al. | 2017-01-05 |
Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity App 20160375108 - Chang; Chien-Hsing ;   et al. | 2016-12-29 |
Humanized Anti-cd22 Antibody App 20160376366 - CHANG; Chien-Hsing ;   et al. | 2016-12-29 |
Therapeutic Use of Anti-CD22 Antibodies for Inducing Trogocytosis App 20160368986 - Chang; Chien-Hsing ;   et al. | 2016-12-22 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 9,522,959 - Govindan , et al. December 20, 2 | 2016-12-20 |
Disease Therapy With Chimeric Antigen Receptor (car) Constructs And T Cells (car-t) Or Nk Cells (car-nk) Expressing Car Constructs App 20160361360 - Chang; Chien-Hsing ;   et al. | 2016-12-15 |
PEGylation by the Dock and Lock (DNL) Technique App 20160361435 - Chang; Chien-Hsing ;   et al. | 2016-12-15 |
Dock-and-Lock (DNL) Vaccines for Cancer Therapy App 20160361405 - Chang; Chien-Hsing ;   et al. | 2016-12-15 |
Humanized anti-CD22 antibody Grant 9,518,115 - Chang , et al. December 13, 2 | 2016-12-13 |
Subcutaneous Anti-hla-dr Monoclonal Antibody For Treatment Of Hematologic Malignancies App 20160355591 - Goldenberg; David M. ;   et al. | 2016-12-08 |
Detection of early-stage pancreatic adenocarcinoma Grant 9,513,293 - Gold , et al. December 6, 2 | 2016-12-06 |
T20 Constructs For Anti-hiv (human Immunodeficiency Virus) Therapy And/or Vaccines App 20160346380 - Stenler; Sofia ;   et al. | 2016-12-01 |
Antibodies Reactive With An Epitope Located In The N-terminal Region Of Muc5ac Comprising Cysteine-rich Subdomain 2 (cys2) App 20160347857 - Liu; Donglin ;   et al. | 2016-12-01 |
Multimeric Complexes with Improved in Vivo Stability, Pharmacokinetics and Efficacy App 20160340443 - Rossi; Edmund A. ;   et al. | 2016-11-24 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 9,499,631 - Govindan , et al. November 22, 2 | 2016-11-22 |
Tetrameric cytokines with improved biological activity Grant 9,498,542 - Chang , et al. November 22, 2 | 2016-11-22 |
Methods Of Treating Cancer With Antibodies That Target The Insulin-like Growth Factor Type I Receptor (igf-1r) App 20160333098 - Chang; Chien-Hsing ;   et al. | 2016-11-17 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 9,493,573 - Govindan , et al. November 15, 2 | 2016-11-15 |
Dock-and-Lock (DNL) Complexes for delivery of interference RNA Grant 9,492,561 - Chang , et al. November 15, 2 | 2016-11-15 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 9,493,574 - Govindan , et al. November 15, 2 | 2016-11-15 |
Antibody-drug conjugates and uses thereof Grant 9,492,566 - Goldenberg , et al. November 15, 2 | 2016-11-15 |
Pro-drug form (P2PDOX) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer Grant 9,486,536 - Govindan , et al. November 8, 2 | 2016-11-08 |
Anti-CD19 Antibodies App 20160319020 - Hansen; Hans J. ;   et al. | 2016-11-03 |
Compositions and methods of use of immunotoxins comprising ranpirnase (Rap) show potent cytotoxic activity Grant 9,481,878 - Chang , et al. November 1, 2 | 2016-11-01 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 9,480,756 - Govindan , et al. November 1, 2 | 2016-11-01 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 9,481,732 - Govindan , et al. November 1, 2 | 2016-11-01 |
Isolation, Detection, Diagnosis And/or Characterization Of Circulating Trop-2-positive Cancer Cells App 20160313339 - Goldenberg; David M. ;   et al. | 2016-10-27 |
Bispecific Antibodies That Neutralize Both Tnf-alpha And Il-6: Novel Therapeutic Agent For Autoimmune Disease App 20160311931 - Goldenberg; David M. ;   et al. | 2016-10-27 |
Therapeutic use of anti-CD22 antibodies for inducing trogocytosis Grant 9,475,883 - Chang , et al. October 25, 2 | 2016-10-25 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 9,475,884 - Govindan , et al. October 25, 2 | 2016-10-25 |
Combination Therapy For Treating Adult Patients With Relapsed/refractory Cd22+ B-cell Acute Lymphoblastic Leukemia App 20160304611 - Chevallier; Patrice ;   et al. | 2016-10-20 |
Antibody-sn-38 Immunoconjugates With A Cl2a Linker App 20160303253 - Govindan; Serengulam V. ;   et al. | 2016-10-20 |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration Grant 9,468,689 - Zeng , et al. October 18, 2 | 2016-10-18 |
Combining Anti-hla-dr Or Anti-trop-2 Antibodies With Microtubule Inhibitors, Parp Inhibitors, Bruton Kinase Inhibitors Or Phosphoinositide 3-kinase Inhibitors Significantly Improves Therapeutic Outcome In Cancer App 20160296633 - Goldenberg; David M. ;   et al. | 2016-10-13 |
Y-90-labeled Anti-cd22 Antibody (epratuzumab Tetraxetan) In Refractory/relapsed Adult Cd22+ B-cell Acute Lymphoblastic Leukemia App 20160296648 - Chevallier; Patrice ;   et al. | 2016-10-13 |
Tumor Therapy By Bispecific Antibody Pretargeting App 20160287732 - Boerman; Otto C. ;   et al. | 2016-10-06 |
Dock-and-lock (DNL) vaccines for cancer therapy Grant 9,457,072 - Chang , et al. October 4, 2 | 2016-10-04 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 9,458,242 - Govindan , et al. October 4, 2 | 2016-10-04 |
PEGylation by the dock and lock (DNL) technique Grant 9,457,100 - Chang , et al. October 4, 2 | 2016-10-04 |
Subcutaneous Administration Of Anti-cd74 Antibody For Systemic Lupus Erythematosus And Autoimmune Disease App 20160279239 - Goldenberg; David M. ;   et al. | 2016-09-29 |
Antibodies reactive with an epitope located in the N-terminal region of MUC5AC comprising cysteine-rich subdomain 2 (Cys2) Grant 9,452,228 - Liu , et al. September 27, 2 | 2016-09-27 |
Multimeric complexes with improved in vivo stability, pharmacokinetics and efficacy Grant 9,446,123 - Rossi , et al. September 20, 2 | 2016-09-20 |
Disease Therapy By Inducing Immune Response To Trop-2 Expressing Cells App 20160264678 - Chang; Chien-Hsing ;   et al. | 2016-09-15 |
Methods of treating cancer with antibodies that target the insulin-like growth factor type I receptor (IGF-1R) Grant 9,441,043 - Chang , et al. September 13, 2 | 2016-09-13 |
Antibody-sn-38 Immunoconjugates With A Cl2a Linker App 20160256562 - Govindan; Serengulam V. ;   et al. | 2016-09-08 |
Compositions and Methods of Use of Immunotoxins Comprising Ranpirnase (Rap) Show Potent Cytotoxic Activity App 20160257947 - Chang; Chien-Hsing ;   et al. | 2016-09-08 |
Delivery System For Cytotoxic Drugs By Bispecific Antibody Pretargeting App 20160250350 - McBride; William J. ;   et al. | 2016-09-01 |
Therapeutic Use Of Anti-cd22 Antibodies For Inducing Trogocytosis App 20160251444 - Chang; Chien-Hsing ;   et al. | 2016-09-01 |
Combination Therapy With Anti-CD74 and Anti-CD20 Antibodies Provides Enhanced Toxicity to B-Cell Diseases App 20160243226 - Chang; Chien-Hsing ;   et al. | 2016-08-25 |
Bispecific antibodies that neutralize both TNF-.alpha. and IL-6: novel therapeutic agent for autoimmune disease Grant 9,416,197 - Goldenberg , et al. August 16, 2 | 2016-08-16 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20160220695 - Govindan; Serengulam V. ;   et al. | 2016-08-04 |
Radiosensitivity Of Fluorophores And Use Of Radioprotective Agents For Dual-modality Imaging App 20160199524 - Hernandez; Reinier ;   et al. | 2016-07-14 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20160193357 - Govindan; Serengulam V. ;   et al. | 2016-07-07 |
Disease therapy by inducing immune response to Trop-2 expressing cells Grant 9,382,329 - Chang , et al. July 5, 2 | 2016-07-05 |
Antibody-SN-38 immunoconjugates with a CL2A linker Grant 9,375,489 - Govindan , et al. June 28, 2 | 2016-06-28 |
T-Cell Redirecting Bispecific Antibodies for Treatment of Disease App 20160176980 - Chang; Chien-Hsing ;   et al. | 2016-06-23 |
T-Cell Redirecting Bispecific Antibodies for Treatment of Disease App 20160176968 - Chang; Chien-Hsing ;   et al. | 2016-06-23 |
Class I anti-CEA antibodies and uses thereof Grant 9,371,393 - Hansen , et al. June 21, 2 | 2016-06-21 |
Pro-drug Form (p2pdox) Of The Highly Potent 2-pyrrolinodoxorubicin Conjugated To Antibodies For Targeted Therapy Of Cancer App 20160166708 - Govindan; Serengulam V. ;   et al. | 2016-06-16 |
Combination therapy with anti-CD74 and anti-CD20 antibodies provides enhanced toxicity to B-cell diseases Grant 9,359,443 - Chang , et al. June 7, 2 | 2016-06-07 |
Delivery system for cytotoxic drugs by bispecific antibody pretargeting Grant 9,352,036 - McBride , et al. May 31, 2 | 2016-05-31 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 9,345,783 - Govindan , et al. May 24, 2 | 2016-05-24 |
Chimeric and Humanized Anti-Histone Antibodies App 20160130333 - Chang; Chien-Hsing ;   et al. | 2016-05-12 |
Interferon Lambda-antibody Complexes App 20160129086 - Chang; Chien-Hsing ;   et al. | 2016-05-12 |
Combining Radioimmunotherapy and Antibody-Drug Conjugates for Improved Cancer Therapy App 20160129140 - Govindan; Serengulam V. ;   et al. | 2016-05-12 |
Combination Therapy With Anti-cd74 And Anti-cd20 Antibodies In Patients With Relapsed And Refractory B-cell Non-hodgkin's Lymphoma App 20160120976 - Goldenberg; David M. ;   et al. | 2016-05-05 |
T-cell redirecting bispecific antibodies for treatment of disease Grant 9,315,567 - Chang , et al. April 19, 2 | 2016-04-19 |
Neoadjuvant Use Of Antibody-drug Conjugates App 20160095939 - Goldenberg; David M. | 2016-04-07 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20160090423 - Govindan; Serengulam V. ;   et al. | 2016-03-31 |
Anti-mucin Antibodies For Early Detection And Treatment Of Pancreatic Cancer App 20160090413 - Liu; Donglin ;   et al. | 2016-03-31 |
Dock-and-Lock (DNL) Constructs for Human Immunodeficiency Virus (HIV) Therapy App 20160089449 - Chang; Chien-Hsing ;   et al. | 2016-03-31 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20160082003 - Govindan; Serengulam V. ;   et al. | 2016-03-24 |
Pro-drug form (P2PDox) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer Grant 9,283,286 - Govindan , et al. March 15, 2 | 2016-03-15 |
Detection of Early-Stage Pancreatic Adenocarcinoma App 20160069885 - Gold; David V. ;   et al. | 2016-03-10 |
Methods of treating rapidly progressive glomerulonephritis using chimeric and humanized anti-histone H4 antibodies Grant 9,278,129 - Chang , et al. March 8, 2 | 2016-03-08 |
Identification of Cancer Genes by In-Vivo Fusion of Human Cancer Cells and Animal Cells App 20160060707 - Goldenberg; David M. ;   et al. | 2016-03-03 |
Interferon lambada-antibody complexes Grant 9,272,029 - Chang , et al. March 1, 2 | 2016-03-01 |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy Grant 9,272,057 - Govindan , et al. March 1, 2 | 2016-03-01 |
Methods and Compositions for Improved Labeling of Targeting Peptides App 20160045626 - McBride; William J. ;   et al. | 2016-02-18 |
Immunotherapy Of Autoimmune Disorders Using Antibodies Which Target B-cells App 20160039941 - GOLDENBERG; David M. ;   et al. | 2016-02-11 |
Stable Compositions of High-Concentration Allotype-Selected Antibodies for Small-Volume Administration App 20160032008 - Zeng; Li ;   et al. | 2016-02-04 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20160032004 - Govindan; Serengulam V. ;   et al. | 2016-02-04 |
Therapeutic Use of Anti-CD22 Antibodies for Inducing Trogocytosis App 20160032003 - Chang; Chien-Hsing ;   et al. | 2016-02-04 |
Dock-and-lock (DNL) constructs for human immunodeficiency virus (HIV) therapy Grant 9,248,184 - Chang , et al. February 2, 2 | 2016-02-02 |
Humanized Anti-HLA-DR Antibodies App 20160024212 - Goldenberg; David M. ;   et al. | 2016-01-28 |
Anti-mucin antibodies for early detection and treatment of pancreatic cancer Grant 9,238,084 - Liu , et al. January 19, 2 | 2016-01-19 |
Detection of early-stage pancreatic adenocarcinoma Grant 9,238,081 - Gold , et al. January 19, 2 | 2016-01-19 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 9,233,172 - Govindan , et al. January 12, 2 | 2016-01-12 |
Crosslinking Of Cd22 By Epratuzumab Triggers Bcr Signaling And Caspase-dependent Apoptosis In Hematopoietic Cancer Cells App 20160000915 - Chang; Chien-Hsing ;   et al. | 2016-01-07 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 9,226,973 - Govindan , et al. January 5, 2 | 2016-01-05 |
Methods and Compositions for Generating Bioactive Assemblies of Increased Complexity and Uses App 20150374846 - Chang; Chien-Hsing ;   et al. | 2015-12-31 |
Antibody-drug Conjugates And Uses Thereof App 20150366988 - Goldenberg; David M. ;   et al. | 2015-12-24 |
Humanized Anti-cd22 Antibody App 20150344573 - Chang; Chien-Hsing ;   et al. | 2015-12-03 |
Class I Anti-CEA Antibodies and Uses Thereof App 20150343087 - Hansen; Hans J. ;   et al. | 2015-12-03 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 9,198,978 - Govindan , et al. December 1, 2 | 2015-12-01 |
Therapeutic use of anti-CD22 antibodies for inducing trogocytosis Grant 9,192,664 - Chang , et al. November 24, 2 | 2015-11-24 |
Humanized anti-HLA-DR antibodies Grant 9,187,561 - Goldenberg , et al. November 17, 2 | 2015-11-17 |
Anti-Mucin Antibodies for Early Detection and Treatment of Pancreatic Cancer App 20150320872 - Gold; David V. ;   et al. | 2015-11-12 |
Humanized antibodies and methods of humanizing antibodies Grant 9,184,781 - Hansen , et al. November 10, 2 | 2015-11-10 |
Stable compositions of high-concentration allotype-selected antibodies for small-volume administration Grant 9,180,205 - Zeng , et al. November 10, 2 | 2015-11-10 |
Antibodies Reactive With An Epitope Located In The N-terminal Region Of Muc5ac Comprising Cysteine-rich Subdomain 2 (cys2) App 20150315289 - Liu; Donglin ;   et al. | 2015-11-05 |
Antibody-sn-38 Immunoconjugates With A Cl2a Linker App 20150306243 - Govindan; Serengulam V. ;   et al. | 2015-10-29 |
Anthracycline-Antibody Conjugates for Cancer Therapy App 20150306244 - Griffiths; Gary L. ;   et al. | 2015-10-29 |
Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules App 20150307524 - D'Souza; Christopher A. ;   et al. | 2015-10-29 |
Methods and compositions for generating bioactive assemblies of increased complexity and uses Grant 9,169,470 - Chang , et al. October 27, 2 | 2015-10-27 |
Pro-drug Form (p2pdox) Of The Highly Potent 2-pyrrolinodoxorubicin Conjugated To Antibodies For Targeted Therapy Of Cancer App 20150283264 - Govindan; Serengulam V. ;   et al. | 2015-10-08 |
Humanized anti-CD22 antibody Grant 9,139,649 - Chang , et al. September 22, 2 | 2015-09-22 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 9,138,485 - Govindan , et al. September 22, 2 | 2015-09-22 |
Anti-CD19 Antibodies App 20150252110 - Hansen; Hans J. ;   et al. | 2015-09-10 |
Humanized Rfb4 Anti-cd22 Antibody App 20150239974 - Chang; Chien-Hsing ;   et al. | 2015-08-27 |
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules Grant 9,115,172 - D'Souza , et al. August 25, 2 | 2015-08-25 |
Combination Therapy For Inducing Immune Response To Disease App 20150231241 - Chang; Chien-Hsing ;   et al. | 2015-08-20 |
Anthracycline-antibody conjugates for cancer therapy Grant 9,107,962 - Griffiths , et al. August 18, 2 | 2015-08-18 |
Antibody-SN-38 immunoconjugates with a CL2A linker Grant 9,107,960 - Govindan , et al. August 18, 2 | 2015-08-18 |
Methods and Compositions for Treatment of Human Immunodeficiency Virus Infection with Conjugated Antibodies or Antibody Fragments App 20150224192 - Goldenberg; David M. ;   et al. | 2015-08-13 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 9,102,735 - Govindan , et al. August 11, 2 | 2015-08-11 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150216997 - Govindan; Serengulam V. ;   et al. | 2015-08-06 |
Al-f-18-labeled, Al-f-19-labeled And Ga-68-labeled Gastrin-releasing Peptide Receptor (grpr)-antagonists For Imaging Of Prostate Cancer App 20150217006 - McBride; William J. ;   et al. | 2015-08-06 |
Pro-drug form (P2PDOX) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer Grant 9,095,628 - Govindan , et al. August 4, 2 | 2015-08-04 |
Anti-mucin antibodies for early detection and treatment of pancreatic cancer Grant 9,089,618 - Gold , et al. July 28, 2 | 2015-07-28 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150202320 - Govindan; Serengulam V. ;   et al. | 2015-07-23 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150202319 - Govindan; Serengulam V. ;   et al. | 2015-07-23 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150196661 - Govindan; Serengulam V. ;   et al. | 2015-07-16 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150196653 - Govindan; Serengulam V. ;   et al. | 2015-07-16 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150196654 - Govindan; Serengulam V. ;   et al. | 2015-07-16 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150196664 - Govindan; Serengulam V. ;   et al. | 2015-07-16 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150196665 - Govindan; Serengulam V. ;   et al. | 2015-07-16 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150196666 - Govindan; Serengulam V. ;   et al. | 2015-07-16 |
Dosages of Immunoconjugates of Antibodies and SN-38 for Improved Efficacy and Decreased Toxicity App 20150196662 - Govindan; Serengulam V. ;   et al. | 2015-07-16 |
Novel Class of Monospecific and Bispecific Humanized Antibodies that Target the Insulin-like Growth Factor Type I Receptor (IGF-1R) App 20150183880 - Chang; Chien-Hsing ;   et al. | 2015-07-02 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20150182633 - Govindan; Serengulam V. ;   et al. | 2015-07-02 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20150174269 - Govindan; Serengulam V. ;   et al. | 2015-06-25 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20150174270 - Govindan; Serengulam V. ;   et al. | 2015-06-25 |
Humanized L243 Antibodies App 20150166659 - Goldenberg; David M. ;   et al. | 2015-06-18 |
Combining Radioimmunotherapy and Antibody-Drug Conjugates for Improved Cancer Therapy App 20150165075 - Govindan; Serengulam V. ;   et al. | 2015-06-18 |
Anti-cd74 Immunoconjugates And Methods Of Use App 20150166669 - HANSEN; Hans J. ;   et al. | 2015-06-18 |
Anti-mucin Antibodies For Early Detection And Treatment Of Pancreatic Cancer App 20150165076 - Liu; Donglin ;   et al. | 2015-06-18 |
Anti-CD19 antibodies Grant 9,056,917 - Hansen , et al. June 16, 2 | 2015-06-16 |
Chimeric And Humanized Anti-histone Antibodies App 20150150969 - Chang; Chien-Hsing ;   et al. | 2015-06-04 |
Anti-Pancreatic Cancer Antibodies App 20150132768 - Goldenberg; David M. ;   et al. | 2015-05-14 |
Disease Therapy By Inducing Immune Response To Trop-2 Expressing Cells App 20150132217 - Chang; Chien-Hsing ;   et al. | 2015-05-14 |
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules Grant 9,028,800 - D'Souza , et al. May 12, 2 | 2015-05-12 |
Dosages of immunoconjugates of antibodies and SN-38 for improved efficacy and decreased toxicity Grant 9,028,833 - Govindan , et al. May 12, 2 | 2015-05-12 |
Humanized Anti-ceacam5 Antibody And Uses Thereof App 20150125386 - Hansen; Hans J. ;   et al. | 2015-05-07 |
Bispecific Antibodies That Neutralize Both Tnf-alpha And Il-6: Novel Therapeutic Agent For Autoimmune Disease App 20150125450 - Goldenberg; David M. ;   et al. | 2015-05-07 |
Class I Anti-CEA Antibodies and Uses Thereof App 20150111279 - Hansen; Hans J. ;   et al. | 2015-04-23 |
Anti-mucin antibodies for early detection and treatment of pancreatic cancer Grant 9,005,613 - Liu , et al. April 14, 2 | 2015-04-14 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 8,999,344 - Govindan , et al. April 7, 2 | 2015-04-07 |
Anthracycline-Antibody Conjugates for Cancer Therapy App 20150094456 - Griffiths; Gary L. ;   et al. | 2015-04-02 |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy Grant 8,992,931 - Govindan , et al. March 31, 2 | 2015-03-31 |
Humanized L243 antibodies Grant 8,992,917 - Goldenberg , et al. March 31, 2 | 2015-03-31 |
Dye Conjugated Peptides for Fluorescent Imaging App 20150086482 - Regino; Celeste Aida S. ;   et al. | 2015-03-26 |
Chimeric and humanized anti-histone antibodies Grant 8,987,421 - Chang , et al. March 24, 2 | 2015-03-24 |
Anti-CD74 immunoconjugates and methods of use Grant 8,986,699 - Hansen , et al. March 24, 2 | 2015-03-24 |
Anti-pancreatic cancer antibodies Grant 8,974,784 - Goldenberg , et al. March 10, 2 | 2015-03-10 |
Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules App 20150057432 - D'Souza; Christopher A. ;   et al. | 2015-02-26 |
Methods for Generating Stably Linked Complexes Composed of Homodimers, Homotetramers or Dimers of Dimers and Uses App 20150056680 - Chang; Chien-Hsing ;   et al. | 2015-02-26 |
Stably Tethered Structures of Defined Compositions with Multiple Functions or Binding Specificities App 20150050715 - Chang; Chien-Hsing ;   et al. | 2015-02-19 |
Combination Therapy With Anti-CD74 Antibodies Provides Enhanced Toxicity to Malignancies, Autoimmune Disease and Other Diseases App 20150037283 - Chang; Chien-Hsing ;   et al. | 2015-02-05 |
Polymeric Carriers of Therapeutic Agents and Recognition Moieties for Antibody-Based Targeting of Disease Sites App 20150038686 - Govindan; Serengulam V. ;   et al. | 2015-02-05 |
Class I anti-CEA antibodies and uses thereof Grant 8,945,554 - Hansen , et al. February 3, 2 | 2015-02-03 |
Multivalent Antibody Complexes Targeting IGF-1R Show Potent Toxicity Against Solid Tumors App 20150024459 - Chang; Chien-Hsing ;   et al. | 2015-01-22 |
Dock-and-Lock (DNL) Complexes for Therapeutic and Diagnostic Use App 20150024458 - Chang; Chien-Hsing ;   et al. | 2015-01-22 |
Multiple Signaling Pathways Induced by Hexavalent, Monospecific and Bispecific Antibodies for Enhanced Toxicity to B-Cell Lymphomas and Other Diseases App 20150023870 - Chang; Chien-Hsing ;   et al. | 2015-01-22 |
Pro-drug Form (p2pdox) Of The Highly Potent 2-pyrrolinodoxorubicin Conjugated To Antibodies For Targeted Therapy Of Cancer App 20150018516 - Govindan; Serengulam V. ;   et al. | 2015-01-15 |
Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses Grant 8,932,593 - Chang , et al. January 13, 2 | 2015-01-13 |
Methods and Compositions for Generating Bioactive Assemblies of Increased Complexity and Uses App 20150010982 - Chang; Chien-Hsing ;   et al. | 2015-01-08 |
Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules App 20140377177 - D'Souza; Christopher A. ;   et al. | 2014-12-25 |
Anti-Mucin Antibodies for Early Detection and Treatment of Pancreatic Cancer App 20140377173 - Gold; David V. ;   et al. | 2014-12-25 |
Anti-trop-2 Antibody-drug Conjugates And Uses Thereof App 20140377287 - Govindan; Serengulam V. ;   et al. | 2014-12-25 |
Camptothecin Conjugates of Anti-CD22 Antibodies for Treatment of B Cell Diseases App 20140369927 - Govindan; Serengulam V. ;   et al. | 2014-12-18 |
Stably tethered structures of defined compositions with multiple functions or binding specificities Grant 8,906,377 - Chang , et al. December 9, 2 | 2014-12-09 |
Combination therapy with anti-CD74 antibodies provides enhanced toxicity to malignancies, autoimmune disease and other diseases Grant 8,906,378 - Chang , et al. December 9, 2 | 2014-12-09 |
Anthracycline-antibody conjugates for cancer therapy Grant 8,895,013 - Griffiths , et al. November 25, 2 | 2014-11-25 |
Mammalian cell lines for increasing longevity and protein yield from a cell culture Grant 8,889,410 - Goldenberg , et al. November 18, 2 | 2014-11-18 |
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules Grant 8,889,100 - D'Souza , et al. November 18, 2 | 2014-11-18 |
Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites Grant 8,889,835 - Govindan , et al. November 18, 2 | 2014-11-18 |
Multivalent antibody complexes targeting IGF-1R show potent toxicity against solid tumors Grant 8,883,162 - Chang , et al. November 11, 2 | 2014-11-11 |
Dock-and-lock (DNL) complexes for therapeutic and diagnostic use Grant 8,883,160 - Chang , et al. November 11, 2 | 2014-11-11 |
Immunoconjugates with an Intracellularly-Cleavable Linkage App 20140328752 - Govindan; Serengulam V. ;   et al. | 2014-11-06 |
Pro-drug form (P2PDOX) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy of cancer Grant 8,877,202 - Govindan , et al. November 4, 2 | 2014-11-04 |
Multiple signaling pathways induced by hexvalent, monospecific and bispecific antibodies for enhanced toxicity to B-cell lymphomas and other diseases Grant 8,871,216 - Chang , et al. October 28, 2 | 2014-10-28 |
Methods and compositions for generating bioactive assemblies of increased complexity and uses Grant 8,865,176 - Chang , et al. October 21, 2 | 2014-10-21 |
Mammalian Cell Lines for Increasing Longevity and Protein Yield from a Cell Culture App 20140308703 - Goldenberg; David M. ;   et al. | 2014-10-16 |
Anti-CD74 immunoconjugates and methods of use Grant 8,846,002 - Byrd , et al. September 30, 2 | 2014-09-30 |
Camptothecin-binding moiety conjugates Grant 8,834,886 - Govindan , et al. September 16, 2 | 2014-09-16 |
Anti-pancreatic cancer antibodies Grant 8,821,868 - Goldenberg , et al. September 2, 2 | 2014-09-02 |
In vivo copper-free click chemistry for delivery of therapeutic and/or diagnostic agents Grant 8,808,665 - McBride , et al. August 19, 2 | 2014-08-19 |
Anti-mucin antibodies for early detection and treatment of pancreatic cancer Grant 8,795,662 - Gold , et al. August 5, 2 | 2014-08-05 |
Antibody therapy Grant 8,778,342 - Goldenberg , et al. July 15, 2 | 2014-07-15 |
Class I anti-CEA antibodies and uses thereof Grant 8,771,690 - Hansen , et al. July 8, 2 | 2014-07-08 |
Mammalian cell lines for increasing longevity and protein yield from a cell culture Grant 8,771,987 - Goldenberg , et al. July 8, 2 | 2014-07-08 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 8,759,496 - Govindan , et al. June 24, 2 | 2014-06-24 |
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules Grant 8,758,726 - D'Souza , et al. June 24, 2 | 2014-06-24 |
RS7 antibodies Grant 8,758,752 - Govindan , et al. June 24, 2 | 2014-06-24 |
Immunoconjugates with an intracellularly-cleavable linkage Grant 8,741,300 - Govindan , et al. June 3, 2 | 2014-06-03 |
Humanized anti-HLA-DR antibodies Grant 8,722,047 - Goldenberg , et al. May 13, 2 | 2014-05-13 |
Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules Grant 8,709,382 - D'Souza , et al. April 29, 2 | 2014-04-29 |
Camptothecin-binding moiety conjugates Grant 08617558 - | 2013-12-31 |
Camptothecin-Binding Moiety Conjugates App 20120328564A1 - | 2012-12-27 |
Modular Method to Prepare Tetrameric Cytokines with Improved Pharmacokinetics by the Dock-and-Lock (DNL) Technology App 20110318306A1 - | 2011-12-29 |