Patent | Date |
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Methods For Treating Cancer Using Combinations Of Anti-cx3cr1 And Immune Checkpoint Blockade Agents App 20220289854 - Freeman; Gordon J. ;   et al. | 2022-09-15 |
Agents that modulate immune cell activation and methods of use thereof Grant 11,359,020 - Freeman , et al. June 14, 2 | 2022-06-14 |
Human anti-PD-1, PD-L1, and PD-L2 antibodies and uses therefor Grant 11,261,251 - Freeman , et al. March 1, 2 | 2022-03-01 |
Methods Of Reducing Liver Pd-1-expressing Cd8+ T Cells Using Pd-1 Fc Fusion Proteins That Bind Fc Receptors App 20220041726 - Freeman; Gordon J. ;   et al. | 2022-02-10 |
METHODS FOR UPREGULATING IMMUNE RESPONSES USING COMBINATIONS OF ANTI-RGMb AND ANTI-PD-1 AGENTS App 20220033502 - Freeman; Gordon J. ;   et al. | 2022-02-03 |
Methods for upregulating immune responses using combinations of anti-RGMb and anti-PD-1 agents Grant 11,220,545 - Freeman , et al. January 11, 2 | 2022-01-11 |
Regulatory T cell PD-1 modulation for regulating T cell effector immune responses Grant 11,207,393 - Sharpe , et al. December 28, 2 | 2021-12-28 |
Methods of reducing liver PD-1-expressing CD8+ T cells using PD-1 Fc fusion proteins that bind Fc receptors Grant 11,124,569 - Freeman , et al. September 21, 2 | 2021-09-21 |
Compositions and methods for inhibiting viral entry Grant 11,116,818 - Choe , et al. September 14, 2 | 2021-09-14 |
Methods For Treating Pten Deficient Epithelial Cancers Using A Combination Of Anti-pi3kbeta And Anti-immune Checkpoint Agents App 20210267991 - Zhao; Jean ;   et al. | 2021-09-02 |
Kir3dl3 As An Hhla2 Receptor, Anti-hhla2 Antibodies, And Uses Thereof App 20210115144 - Freeman; Gordon J. ;   et al. | 2021-04-22 |
Methods for treating PTEN deficient epithelial cancers using a combination of anti-PI3KBETA and anti-immune checkpoint agents Grant 10,960,008 - Zhao , et al. March 30, 2 | 2021-03-30 |
PD-L2 biomarkers predictive of PD-1 pathway inhibitor responses in esophagogastric cancers Grant 10,948,492 - Bass , et al. March 16, 2 | 2021-03-16 |
Single agent anti-PD-L1 and PD-L2 dual binding antibodies and methods of use Grant 10,934,353 - Freeman , et al. March 2, 2 | 2021-03-02 |
Methods For Treating Cancer Using Combinations Of Anti-btnl2 And Immune Checkpoint Blockade Agents App 20210032334 - Freeman; Gordon J. ;   et al. | 2021-02-04 |
Human Anti-pd-1, Pd-l1, And Pd-l2 Antibodies And Uses Therefor App 20200172616 - FREEMAN; Gordon J. ;   et al. | 2020-06-04 |
Anti-phosphotyrosinylated Pd-1 Antibodies And Uses Thereof App 20200115452 - Freeman; Gordon J. ;   et al. | 2020-04-16 |
Agents That Modulate Immune Cell Activation And Methods Of Use Thereof App 20200095325 - Freeman; Gordon J. ;   et al. | 2020-03-26 |
Compositions And Methods For Identification, Assessment, Prevention, And Treatment Of Melanoma Using Pd-l1 Isoforms App 20190375818 - Hodi; F. Stephen ;   et al. | 2019-12-12 |
Anti-pd-l1 Monoclonal Antibodies And Fragments Thereof App 20190330350 - Freeman; Gordon J. ;   et al. | 2019-10-31 |
Agents that modulate immune cell activation and methods of use thereof Grant 10,457,733 - Freeman , et al. Oc | 2019-10-29 |
Methods For Treating Pten Deficient Epithelial Cancers Using A Combination Of Anti-pi3kbeta And Anti-immune Checkpoint Agents App 20190298728 - Zhao; Jean ;   et al. | 2019-10-03 |
Human anti-PD-1, PD-L1, and PD-L2 antibodies and uses therefor Grant 10,370,448 - Freeman , et al. | 2019-08-06 |
Anti-PD-L1 monoclonal antibodies and fragments thereof Grant 10,202,454 - Freeman , et al. Feb | 2019-02-12 |
Human Anti-pd-1, Pd-l1, And Pd-l2 Antibodies And Uses Therefor App 20180371084 - FREEMAN; Gordon J. ;   et al. | 2018-12-27 |
Methods Of Reducing Liver Pd-1-expressing Cd8+ T Cells Using Pd-1 Fc Fusion Proteins That Bind Fc Receptors App 20180355039 - Freeman; Gordon J. ;   et al. | 2018-12-13 |
Regulatory T Cell Pd-1 Modulation For Regulating T Cell Effector Immune Responses App 20180303922 - Sharpe; Arlene H. ;   et al. | 2018-10-25 |
Methods Related To Tim 3, A Th1-specific Cell Surface Molecule, For Activating Antigen Presenting Cells App 20180271977 - Kuchroo; Vijay K. ;   et al. | 2018-09-27 |
Pd-l2 Biomarkers Predictive Of Pd-1 Pathway Inhibitor Responses In Esophagogastric Cancers App 20180238884 - Bass; Adam ;   et al. | 2018-08-23 |
Single Agent Anti-pd-l1 And Pd-l2 Dual Binding Antibodies And Methods Of Use App 20180201680 - Freeman; Gordon J. ;   et al. | 2018-07-19 |
Human anti-PD-1, PD-L1, and PD-L2 antibodies and uses therefor Grant 10,011,656 - Freeman , et al. July 3, 2 | 2018-07-03 |
Methods related to TIM 3, a TH1-specific cell surface molecule, for activating antigen presenting cells Grant 9,962,440 - Kuchroo , et al. May 8, 2 | 2018-05-08 |
METHODS FOR UPREGULATING IMMUNE RESPONSES USING COMBINATIONS OF ANTI-RGMb AND ANTI-PD-1 AGENTS App 20180002422 - Freeman; Gordon J. ;   et al. | 2018-01-04 |
Single agent anti-PD-L1 and PD-L2 dual binding antibodies and methods of use Grant 9,845,356 - Freeman , et al. December 19, 2 | 2017-12-19 |
Modulation of TIM receptor activity in combination with cytoreductive therapy Grant 9,683,049 - Jones , et al. June 20, 2 | 2017-06-20 |
AGENTS THAT MODULATE RGMb-NEOGENIN-BMP SIGNALING AND METHODS OF USE THEREOF App 20160347844 - Dekruyff; Rosemarie ;   et al. | 2016-12-01 |
Compositions And Methods For Identification, Assessment, Prevention, And Treatment Of Melanoma Using Pd-l1 Isoforms App 20160340407 - Hodi; F. Stephen ;   et al. | 2016-11-24 |
Anti-pd-l1 Monoclonal Antibodies And Fragments Thereof App 20160272712 - Freeman; Gordon J. ;   et al. | 2016-09-22 |
Human Anti-pd-1, Pd-l1, And Pd-l2 Antibodies And Uses Therefor App 20160137731 - FREEMAN; Gordon J. ;   et al. | 2016-05-19 |
Methods related to TIM 3, a Th1-specific cell surface molecule, for activating antigen presenting cells Grant 9,333,256 - Kuchroo , et al. May 10, 2 | 2016-05-10 |
Agents That Modulate Immune Cell Activation and Methods of Use Thereof App 20150299322 - Freeman; Gordon J. ;   et al. | 2015-10-22 |
Compositions And Methods For Inhibiting Viral Entry App 20150297677 - Choe; Hyeryun ;   et al. | 2015-10-22 |
Human anti-PD-1 antibodies and uses therefor Grant 9,102,727 - Freeman , et al. August 11, 2 | 2015-08-11 |
Single Agent Anti-PD-L1 and PD-L2 Dual Binding Antibodies and Methods of Use App 20150197571 - Freeman; Gordon J. ;   et al. | 2015-07-16 |
Methods Related To Tim 3, A Th1-specific Cell Surface Molecule, For Activating Antigen Presenting Cells App 20150044230 - Kuchroo; Vijay K. ;   et al. | 2015-02-12 |
Methods Related To Tim 3, A Th1-specific Cell Surface Molecule, For Activating Antigen Presenting Cells App 20150044229 - Kuchroo; Vijay K. ;   et al. | 2015-02-12 |
Modulation of Tim Receptor Activity in Combination with Cytoreductive Therapy App 20150023986 - Jones; Jennifer ;   et al. | 2015-01-22 |
Methods Related To Tim 3, A Th1-specific Cell Surface Molecule, For Activating Antigen Presenting Cells App 20140242094 - Kuchroo; Vijay K. ;   et al. | 2014-08-28 |
Modulation of TIM receptor activity in combination with cytoreductive therapy Grant 8,709,412 - Jones , et al. April 29, 2 | 2014-04-29 |
Methods related to TIM 3, a Th1-specific cell surface molecule, for activating antigen presenting cells Grant 8,697,069 - Kuchroo , et al. April 15, 2 | 2014-04-15 |
Human Anti-pd-1, Pd-l1, And Pd-l2 Antibodies And Uses Therefor App 20130291136 - FREEMAN; Gordon J. ;   et al. | 2013-10-31 |
Anti-PD-L1 antibodies and uses therefor Grant 8,552,154 - Freeman , et al. October 8, 2 | 2013-10-08 |
Compositions And Methods Related To Tim 3, A Th1-specific Cell Surface Molecule App 20120315286 - Kuchroo; Vijay K. ;   et al. | 2012-12-13 |
Modulation Of Tim Receptor Activity In Combination With Cytoreductive Therapy App 20120156224 - Jones; Jennifer ;   et al. | 2012-06-21 |
Compositions and methods related to TIM-3, a TH1-specific cell surface molecule Grant 8,101,176 - Kuchroo , et al. January 24, 2 | 2012-01-24 |
Human Anti-pd-1, Pd-l1, And Pd-l2 Antibodies And Uses Therefor App 20110271358 - Freeman; Gordon J. ;   et al. | 2011-11-03 |
Tumor cells with increased immunogenicity and uses therfor Grant 8,026,224 - Ostrand-Rosenberg , et al. September 27, 2 | 2011-09-27 |
PD-1, A Receptor for B7-4, and Uses Therefor App 20110033884 - Wood; Clive ;   et al. | 2011-02-10 |
Agents that modulate the interaction of B7-1 polypeptide with PD-L1 and methods of use thereof Grant 7,722,868 - Freeman , et al. May 25, 2 | 2010-05-25 |
Methods for upregulating an immune response with agents that inhibit the intereaction between PD-L2 and PD-1 Grant 7,709,214 - Freeman , et al. May 4, 2 | 2010-05-04 |
Nucleic acids encoding CD100 molecules Grant 7,700,102 - Hall , et al. April 20, 2 | 2010-04-20 |
Methods for screening for compounds that modulate PD-1 signaling Grant 7,700,301 - Wood , et al. April 20, 2 | 2010-04-20 |
Methods of upmodulating an immune response with non-activating forms of B7-4 Grant 7,638,492 - Wood , et al. December 29, 2 | 2009-12-29 |
Nucleic acid molecules encoding B7-1 Grant 7,619,078 - Sharpe , et al. November 17, 2 | 2009-11-17 |
T Cell Regulatory Genes And Methods Of Use Thereof App 20090252737 - McIntire; Jennifer Jones ;   et al. | 2009-10-08 |
Methods of inhibiting T cell proliferation or IL-2 accumulation with CTLA-4 specific antibodies Grant 7,592,007 - Gribben , et al. September 22, 2 | 2009-09-22 |
T cell regulatory genes and methods of use thereof Grant 7,553,939 - McIntire , et al. June 30, 2 | 2009-06-30 |
Compositions And Methods Related To Tim 3, A Th1-specific Cell Surface Molecule App 20090110687 - Kuchroo; Vijay ;   et al. | 2009-04-30 |
Compositions and methods related to TIM-3, a Th1-specific cell surface molecule Grant 7,470,428 - Kuchroo , et al. December 30, 2 | 2008-12-30 |
Nucleic acids encoding B7-2 fusion proteins Grant 7,459,544 - Freeman , et al. December 2, 2 | 2008-12-02 |
PD-1, a receptor for B7-4, and uses therefor App 20080274490 - Wood; Clive R. ;   et al. | 2008-11-06 |
PD-1, a receptor for B7-4, and uses therefor App 20070202100 - Wood; Clive ;   et al. | 2007-08-30 |
Novel forms of T cell costimulatory molecules and uses therefor App 20070106070 - Sharpe; Arlene H. ;   et al. | 2007-05-10 |
Methods of inducing a T cell mediated immune response by administering antigen presenting B cells Grant 7,195,758 - Schultze , et al. March 27, 2 | 2007-03-27 |
Agents that modulate immune cell activation and methods of use thereof App 20070065427 - Freeman; Gordon J. ;   et al. | 2007-03-22 |
Methods Of Inducing A T Cell Mediated Immune Response By Administering Antigen Presenting B Cells App 20070031811 - Schultze; Joachim L. ;   et al. | 2007-02-08 |
T cell costimulatory polypeptides containing alternative domains Grant 7,153,934 - Sharpe , et al. December 26, 2 | 2006-12-26 |
Methods for selectively modulating a Th2-type response within a population of activated CD4+ T cells App 20060233795 - Freeman; Gordon J. ;   et al. | 2006-10-19 |
Methods for screening for compounds that modulate pd-1 signaling Grant 7,105,328 - Wood , et al. September 12, 2 | 2006-09-12 |
PD-1, a receptor for B7-4, and uses therefor Grant 7,101,550 - Wood , et al. September 5, 2 | 2006-09-05 |
Tumor cells with increased immunogenicity and uses therfor App 20060099195 - Ostrand-Rosenberg; Suzanne ;   et al. | 2006-05-11 |
Tumor cells modified to express B7-2 with increased immunogenicity and uses therefor App 20050129670 - Freeman, Gordon J. ;   et al. | 2005-06-16 |
Methods for inhibiting the interaction of B7-2 with its natural ligand Grant 6,824,779 - Freeman , et al. November 30, 2 | 2004-11-30 |
Therapeutic compositions for inhibiting the interactions of B7-1 and B7-2 with their natural ligands App 20040230051 - Freeman, Gordon J. ;   et al. | 2004-11-18 |
Downmodulating an immune response with multivalent antibodies to PD-1 Grant 6,808,710 - Wood , et al. October 26, 2 | 2004-10-26 |
Methods of inhibiting T cell proliferation or IL-2 accumulation with CTLA-4 specific antibodies App 20040202650 - Gribben, John G. ;   et al. | 2004-10-14 |
B-7 domain-specific antibodies App 20040192899 - Sharpe, Arlene H. ;   et al. | 2004-09-30 |
Tumor cells modified to express B7-2 with increased immunogenicity and uses therefor Grant 6,723,705 - Freeman , et al. April 20, 2 | 2004-04-20 |
Methods of inhibiting T cell proliferation or IL-2 accumulation with CTLA4- specific antibodies Grant 6,719,972 - Gribben , et al. April 13, 2 | 2004-04-13 |
Compositions and methods related to TIM-3, a Th1-specific cell surface molecule App 20040005322 - Kuchroo, Vijay K. ;   et al. | 2004-01-08 |
Agents that modulate immune cell activation and methods of use thereof App 20030232323 - Freeman, Gordon J. ;   et al. | 2003-12-18 |
Polypeptides comprising a B7 extracellular domain Grant 6,653,444 - Freeman , et al. November 25, 2 | 2003-11-25 |
DNA encoding B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells App 20030170821 - Freeman, Gordon J. ;   et al. | 2003-09-11 |
Nucleic acids encoding CD100 molecules App 20030158402 - Hall, Kathryn T. ;   et al. | 2003-08-21 |
B7-specific antibodies Grant 6,608,180 - Sharpe , et al. August 19, 2 | 2003-08-19 |
Therapeutic compositions for inhibiting the interactions of B7-1 and B7-2 with their natural ligands Grant 6,605,279 - Freeman , et al. August 12, 2 | 2003-08-12 |
T cell regulatory genes and methods of use therof App 20030124114 - McIntire, Jennifer Jones ;   et al. | 2003-07-03 |
Tumor cells with increased immunogenicity and uses therefor App 20030124103 - Ostrand-Rosenberg, Suzanne ;   et al. | 2003-07-03 |
CD100 antigen and uses therefor Grant 6,576,754 - Hall , et al. June 10, 2 | 2003-06-10 |
Novel forms of T cell costimulatory molecules and uses therefor App 20030045703 - Sharpe, Arlene H. ;   et al. | 2003-03-06 |
PD-1, a receptor for B7-4, and uses therefor App 20030044768 - Wood, Clive ;   et al. | 2003-03-06 |
Nucleic Acids Encoding Cd100 Molecules App 20030044416 - HALL, KATHRYN T. ;   et al. | 2003-03-06 |
Methods for selectively modulating a Th2-type response within a population of activated CD4+ T cells App 20020182727 - Freeman, Gordon J. ;   et al. | 2002-12-05 |
PD-1, a receptor for B7-4, and uses therefor App 20020160000 - Wood, Clive ;   et al. | 2002-10-31 |
Method of promoting b-cell proliferation and activation with CD40 ligand and cyclosporin Grant 6,465,251 - Schultze , et al. October 15, 2 | 2002-10-15 |
Novel forms of T cell costimulatory molecules and uses therefor App 20020098542 - Sharpe, Arlene H. ;   et al. | 2002-07-25 |
Novel Ctla4/cd28 Ligands And Uses Therefor App 20020086414 - FREEMAN, GORDON J. ;   et al. | 2002-07-04 |
Tumor cells with increased immunogenicity and uses therefor App 20020086421 - Ostrand-Rosenberg, Suzanne ;   et al. | 2002-07-04 |
Method For Selectively Stimulating Proliferation Of T Cells App 20020076407 - JUNE, CARL H. ;   et al. | 2002-06-20 |
Methods for modulating T cell unresponsiveness App 20020051784 - Boussiotis, Vassiliki A. ;   et al. | 2002-05-02 |
Tumor cells with increased immunogenicity and uses therefor Grant 6,319,709 - Ostrand-Rosenberg , et al. November 20, 2 | 2001-11-20 |
Tumor cells with increased immunogenicity and uses therefor Grant 6,149,905 - Ostrand-Rosenberg , et al. November 21, 2 | 2000-11-21 |
Fusion proteins of novel CTLA4/CD28 ligands and uses therefore Grant 6,130,316 - Freeman , et al. October 10, 2 | 2000-10-10 |
CTLA4/CD28 ligands and uses therefor Grant 6,084,067 - Freeman , et al. July 4, 2 | 2000-07-04 |
DNA encoding, B7, a new member of the IG superfamily with unique expression on activated and neoplastic B cells Grant 6,071,716 - Freeman , et al. June 6, 2 | 2000-06-06 |
B7-2: a CTLA4/CD28 ligand Grant 5,942,607 - Freeman , et al. August 24, 1 | 1999-08-24 |
Tumor cells modified to express B7-2 with increased immunogenicity and uses therefor Grant 5,861,310 - Freeman , et al. January 19, 1 | 1999-01-19 |
Tumor cells with increased immunogenicity and uses therefor Grant 5,858,776 - Ostrand-Rosenberg , et al. January 12, 1 | 1999-01-12 |
Methods for selectively stimulating proliferation of T cells Grant 5,858,358 - June , et al. January 12, 1 | 1999-01-12 |
Fastener means for a leg brace to connect to a shoe Grant 3,999,540 - Freeman December 28, 1 | 1976-12-28 |