U.S. patent number RE44,693 [Application Number 12/507,124] was granted by the patent office on 2014-01-07 for beads bound to a solid support and to nucleic acids. This patent grant is currently assigned to Sequenom, Inc.. The grantee listed for this patent is Hubert Koster, David M. Lough. Invention is credited to Hubert Koster, David M. Lough.
United States Patent | RE44,693 |
Koster , et al. | January 7, 2014 |
Novel compositions comprised of at least one bead conjugated to a solid support and further conjugated to at least one nucleic acid and preferred methods for making the novel compositions are described. As compared to "flat" surfaces, beads linked to a solid support provide an increased surface area for immobilization of nucleic acids. Furthermore, by selecting a bead with the desired functionality, a practitioner can select a functionalization chemistry for immobilizing nucleic acids, which is different from the chemistry of the solid support.
Inventors: | Koster; Hubert (Berlin, DE), Lough; David M. (Cambridge, MA) | ||||||||||
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Applicant: |
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Assignee: | Sequenom, Inc. (San Diego,
CA) |
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Family ID: | 41327979 | ||||||||||
Appl. No.: | 12/507,124 | ||||||||||
Filed: | July 22, 2009 |
Application Number | Filing Date | Patent Number | Issue Date | ||
---|---|---|---|---|---|
10277021 | Oct 17, 2002 | Re. 41005 | |||
08746036 | Nov 6, 1996 | 5900481 | |||
Reissue of: | 08933792 | Sep 19, 1997 | 6133436 | Oct 17, 2000 | |
Current U.S. Class: | 435/6.11; 435/288.4; 525/332.2; 536/24.3; 435/6.1; 435/6.12; 536/25.4; 536/23.1; 502/233; 436/501 |
Current CPC Class: | C12Q 1/6837 (20130101); C12Q 1/6872 (20130101); C07H 21/00 (20130101); C12Q 1/6837 (20130101); C12Q 2525/197 (20130101); C12Q 2523/10 (20130101); C12Q 2531/113 (20130101); C12Q 1/6837 (20130101); C12Q 2565/537 (20130101); C12Q 2523/10 (20130101); C12Q 2565/627 (20130101); C12Q 1/6837 (20130101); C12Q 2565/507 (20130101); C12Q 1/6872 (20130101); C12Q 2565/518 (20130101); C12Q 2535/101 (20130101); B01J 2219/0052 (20130101); B01J 2219/00497 (20130101); B01J 2219/00659 (20130101); B01J 2219/00315 (20130101); B01J 2219/0072 (20130101); B01J 2219/00648 (20130101); G01N 2035/1069 (20130101); B01J 2219/00527 (20130101); B01J 2219/005 (20130101); G01N 35/1067 (20130101); B01J 2219/00387 (20130101); C40B 40/06 (20130101); B01J 2219/00511 (20130101); B01J 2219/00317 (20130101); B01J 2219/00504 (20130101); B01J 2219/00585 (20130101); B01J 2219/00722 (20130101); B01J 2219/00596 (20130101); C40B 40/10 (20130101); C40B 60/14 (20130101); B01J 2219/00725 (20130101); B01J 2219/00468 (20130101) |
Current International Class: | C12Q 1/68 (20060101); C07H 21/00 (20060101); C07H 21/04 (20060101) |
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