U.S. patent number RE39,221 [Application Number 10/761,096] was granted by the patent office on 2006-08-01 for composition comprising a tramadol material and acetaminophen and its use. This patent grant is currently assigned to Ortho-McNeil Pharmaceutical, Inc.. Invention is credited to Robert B. Raffa, Jeffrey L. Vaught.
United States Patent | RE39,221 |
Raffa , et al. | August 1, 2006 |
**Please see images for: ( Certificate of Correction ) ** |
This invention relates to a composition comprising a tramadol material and acetaminophen, and its use. As used herein tramadol refers to various forms of tramadol. The compositions are pharmacologically useful in treating pain and tussive conditions. The compositions are also subject to less opioid side-effects such as abuse liability, tolerance, constipation and respiratory depression. Furthermore, where the components of the compositions are within certain ratios the pharmacological effects of the compositions are superadditive (synergistic).
Inventors: | Raffa; Robert B. (Norristown, PA), Vaught; Jeffrey L. (Glenmoore, PA) |
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Assignee: | Ortho-McNeil Pharmaceutical,
Inc. (Raritan, NJ) |
Family ID: | 36791806 |
Appl. No.: | 10/761,096 |
Filed: | January 20, 2004 |
Application Number | Filing Date | Patent Number | Issue Date | ||
---|---|---|---|---|---|
07755924 | Sep 6, 1991 | ||||
Reissue of: | 07974865 | Nov 10, 1992 | 05336691 | Aug 9, 1994 | |
Current U.S. Class: | 514/629; 514/650; 514/649; 514/646 |
Current CPC Class: | A61P 29/00 (20180101); A61P 25/04 (20180101); A61K 31/165 (20130101); A61K 31/165 (20130101); A61K 31/135 (20130101); A61K 31/165 (20130101); A61K 2300/00 (20130101) |
Current International Class: | A61K 31/16 (20060101) |
Field of Search: | ;514/629,646,649,650 |
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