U.S. patent number 8,386,046 [Application Number 13/251,856] was granted by the patent office on 2013-02-26 for screening devices and methods for obstructive sleep apnea therapy. This patent grant is currently assigned to Apnex Medical, Inc.. The grantee listed for this patent is Stephen L. Bolea, Peter R. Eastwood, David R. Hillman, Wondimeneh Tesfayesus. Invention is credited to Stephen L. Bolea, Peter R. Eastwood, David R. Hillman, Wondimeneh Tesfayesus.
United States Patent | 8,386,046 |
Tesfayesus , et al. | February 26, 2013 |
Devices and methods for treating obstructive sleep apnea by first performing an assessment of the patient that involves observing the patient's upper airway during a tongue protrusion maneuver. The assessment may, for example, be done using endoscopy to observe the upper airway while the patient is awake in the supine position. An adequate response of the upper airway during the tongue protrusion maneuver is indicative of likely therapeutic success with hypoglossal nerve stimulation, and may be used for making clinical decisions. The principles of the present invention may be applied to other therapeutic interventions for OSA involving the upper airway.
Inventors: | Tesfayesus; Wondimeneh (St. Paul, MN), Bolea; Stephen L. (Watertown, MN), Eastwood; Peter R. (Floreat, AU), Hillman; David R. (Nedlands, AU) | ||||||||||
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Applicant: |
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Assignee: | Apnex Medical, Inc. (St. Paul,
MN) |
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Family ID: | 46576313 | ||||||||||
Appl. No.: | 13/251,856 | ||||||||||
Filed: | October 3, 2011 |
Document Identifier | Publication Date | |
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US 20120197340 A1 | Aug 2, 2012 | |
Application Number | Filing Date | Patent Number | Issue Date | ||
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13205315 | Aug 8, 2011 | ||||
13113524 | May 23, 2011 | ||||
61437573 | Jan 28, 2011 | ||||
61467758 | Mar 25, 2011 | ||||
Current U.S. Class: | 607/48; 607/62 |
Current CPC Class: | A61N 1/3611 (20130101); A61N 1/0556 (20130101); A61N 1/3601 (20130101); A61N 1/37235 (20130101); A61N 1/36139 (20130101); A61N 1/3615 (20130101); A61B 5/4818 (20130101); A61N 1/36132 (20130101); A61B 5/0809 (20130101); A61B 5/0826 (20130101) |
Current International Class: | A61N 1/36 (20060101) |
Field of Search: | ;607/48,42,2,1,62 |
758030 | April 1904 | Carence |
1520930 | December 1924 | Calhoun |
1701277 | February 1929 | Shindel |
1914418 | June 1933 | Goyena |
2046664 | July 1936 | Weaver |
2151227 | March 1939 | Pawelek |
2237954 | April 1941 | Wilson |
2243360 | May 1941 | Slatis |
2274886 | March 1942 | Carroll |
2526586 | October 1950 | Shuff |
2693799 | November 1954 | Herman |
2777442 | January 1957 | Zelano |
2928388 | March 1960 | Jaroslaw |
3457917 | July 1969 | Mercurio |
3513839 | May 1970 | Vacante |
3680555 | August 1972 | Warncke |
3722509 | March 1973 | Nebel |
3774618 | November 1973 | Avery |
3865106 | February 1975 | Palush |
3884223 | May 1975 | Keindl |
3906936 | September 1975 | Habal |
4220150 | September 1980 | King |
4221217 | September 1980 | Amezcua |
4267831 | May 1981 | Aguilar |
4374527 | February 1983 | Iversen |
4567892 | February 1986 | Plicchi et al. |
4573481 | March 1986 | Bullara |
4777963 | October 1988 | McKenna |
4830008 | May 1989 | Meer |
4899750 | February 1990 | Eckwall |
4915105 | April 1990 | Lee |
4919136 | April 1990 | Alt |
4940065 | July 1990 | Tanagho et al. |
4960133 | October 1990 | Hewson |
4996983 | March 1991 | AmRhein |
5016808 | May 1991 | Heil, Jr. et al. |
5105826 | April 1992 | Smits et al. |
5121754 | June 1992 | Mullett |
5133354 | July 1992 | Kallok |
5146918 | September 1992 | Kallok et al. |
5158080 | October 1992 | Kallok |
5174287 | December 1992 | Kallok et al. |
5178156 | January 1993 | Takishima et al. |
5190053 | March 1993 | Meer |
5211173 | May 1993 | Kallok et al. |
5215082 | June 1993 | Kallok et al. |
5277193 | January 1994 | Takishima et al. |
5281219 | January 1994 | Kallok et al. |
5300094 | April 1994 | Kallok et al. |
5324321 | June 1994 | Pohndorf et al. |
5335657 | August 1994 | Terry, Jr. et al. |
5344438 | September 1994 | Testerman et al. |
5388578 | February 1995 | Yomtov et al. |
5392773 | February 1995 | Bertrand |
5417205 | May 1995 | Wang |
5425359 | June 1995 | Liou |
5458629 | October 1995 | Baudino et al. |
5483969 | January 1996 | Testerman et al. |
5485836 | January 1996 | Lincoln |
5485851 | January 1996 | Erickson |
5511543 | April 1996 | Shirley |
5522382 | June 1996 | Sullivan et al. |
5522862 | June 1996 | Testerman et al. |
5531778 | July 1996 | Maschino et al. |
5540732 | July 1996 | Testerman |
5540733 | July 1996 | Testerman et al. |
5540734 | July 1996 | Zabara |
5546938 | August 1996 | McKenzie |
5549655 | August 1996 | Erickson |
5568808 | October 1996 | Rimkus |
5591216 | January 1997 | Testerman et al. |
5630411 | May 1997 | Holscher |
5682881 | November 1997 | Winthrop et al. |
5697105 | December 1997 | White |
5697363 | December 1997 | Hart |
5730122 | March 1998 | Lurie |
5740798 | April 1998 | McKinney |
5752511 | May 1998 | Simmons et al. |
5787884 | August 1998 | Tovey |
5848589 | December 1998 | Welnetz |
5855552 | January 1999 | Houser et al. |
5890491 | April 1999 | Rimkus |
5895360 | April 1999 | Christopherson et al. |
5922014 | July 1999 | Warman et al. |
5938596 | August 1999 | Woloszko et al. |
5944680 | August 1999 | Christopherson et al. |
5947119 | September 1999 | Reznick |
6010459 | January 2000 | Silkoff et al. |
6015389 | January 2000 | Brown |
6021352 | February 2000 | Christopherson et al. |
6021354 | February 2000 | Warman et al. |
6029667 | February 2000 | Lurie |
6041780 | March 2000 | Richard |
6066165 | May 2000 | Racz |
6098624 | August 2000 | Utamaru |
6109262 | August 2000 | Tovey |
6119690 | September 2000 | Pentaleo |
6126611 | October 2000 | Bourgeois et al. |
6132384 | October 2000 | Christopherson et al. |
6198970 | March 2001 | Freed et al. |
6201994 | March 2001 | Warman et al. |
6217527 | April 2001 | Selmon et al. |
6221049 | April 2001 | Selmon et al. |
6231546 | May 2001 | Milo et al. |
6240316 | May 2001 | Richmond et al. |
6244267 | June 2001 | Eifrig |
6251126 | June 2001 | Ottenhoff et al. |
6269269 | July 2001 | Ottenhoff et al. |
6345202 | February 2002 | Richmond et al. |
6366815 | April 2002 | Haugland et al. |
6460539 | October 2002 | Japuntich et al. |
6484725 | November 2002 | Chi |
6511458 | January 2003 | Milo et al. |
6514217 | February 2003 | Selmon et al. |
6542776 | April 2003 | Gordon et al. |
6561188 | May 2003 | Ellis |
6587725 | July 2003 | Durand et al. |
6600956 | July 2003 | Maschino et al. |
6606521 | August 2003 | Paspa et al. |
6626179 | September 2003 | Pedley |
6636767 | October 2003 | Knudson et al. |
6641542 | November 2003 | Cho et al. |
6647289 | November 2003 | Prutchi |
6651652 | November 2003 | Ward |
6718982 | April 2004 | Smith et al. |
6719725 | April 2004 | Milo et al. |
6721603 | April 2004 | Zabara et al. |
6772015 | August 2004 | Dahl et al. |
6776162 | August 2004 | Wood |
6799575 | October 2004 | Carter |
6819958 | November 2004 | Weiner et al. |
6829503 | December 2004 | Alt |
6829508 | December 2004 | Schulman et al. |
RE38705 | February 2005 | Hill et al. |
6876885 | April 2005 | Swoyer et al. |
6881192 | April 2005 | Park |
6883518 | April 2005 | Mittelstadt et al. |
6890306 | May 2005 | Poezevera |
6904320 | June 2005 | Park et al. |
6907295 | June 2005 | Gross et al. |
6928324 | August 2005 | Park et al. |
6978171 | December 2005 | Goetz et al. |
6997177 | February 2006 | Wood |
7027869 | April 2006 | Danek et al. |
7054692 | May 2006 | Whitehurst et al. |
7065410 | June 2006 | Bardy et al. |
7082331 | July 2006 | Park et al. |
7087053 | August 2006 | Vanney |
7089932 | August 2006 | Dodds |
7094206 | August 2006 | Hoffman |
7117036 | October 2006 | Florio |
7128717 | October 2006 | Thatch et al. |
7142919 | November 2006 | Hine et al. |
7149573 | December 2006 | Wang |
7152604 | December 2006 | Hickle et al. |
7155278 | December 2006 | King et al. |
7156098 | January 2007 | Dolezal et al. |
7160252 | January 2007 | Cho |
7160255 | January 2007 | Saadat |
7178524 | February 2007 | Noble |
7200440 | April 2007 | Kim et al. |
7225034 | May 2007 | Ries et al. |
7239918 | July 2007 | Strother et al. |
7242987 | July 2007 | Holleman et al. |
7277749 | October 2007 | Gordon et al. |
7283867 | October 2007 | Strother et al. |
7302951 | December 2007 | Mittelstadt et al. |
7313442 | December 2007 | Velasco et al. |
7346398 | March 2008 | Gross et al. |
7366572 | April 2008 | Heruth et al. |
7396333 | July 2008 | Stahmann et al. |
7438686 | October 2008 | Cho et al. |
7463928 | December 2008 | Lee et al. |
7473227 | January 2009 | Hsu et al. |
7515968 | April 2009 | Metzler et al. |
7524292 | April 2009 | Cho et al. |
7561922 | July 2009 | Cohen et al. |
7591265 | September 2009 | Lee et al. |
7596413 | September 2009 | Libbus et al. |
7596414 | September 2009 | Whitehurst et al. |
7627375 | December 2009 | Bardy et al. |
7630771 | December 2009 | Cauller |
7634315 | December 2009 | Cholette |
7636602 | December 2009 | Baru Fassio et al. |
7657311 | February 2010 | Bardy et al. |
7660632 | February 2010 | Kirby et al. |
7662105 | February 2010 | Hatlestad |
7672728 | March 2010 | Libbus et al. |
7672729 | March 2010 | Koh et al. |
7680537 | March 2010 | Stahmann et al. |
7680538 | March 2010 | Durand et al. |
7684869 | March 2010 | Bradley et al. |
7697984 | April 2010 | Hill et al. |
7697990 | April 2010 | Ujhazy et al. |
7717848 | May 2010 | Heruth et al. |
7720534 | May 2010 | Bardy et al. |
7725195 | May 2010 | Lima et al. |
7725198 | May 2010 | Cross, Jr. et al. |
7734340 | June 2010 | De Ridder |
7734348 | June 2010 | Zhang et al. |
7738952 | June 2010 | Yun et al. |
7747323 | June 2010 | Libbus et al. |
7751880 | July 2010 | Cholette |
7751885 | July 2010 | Bardy et al. |
7758384 | July 2010 | Alexander et al. |
7765000 | July 2010 | Zhang et al. |
7769461 | August 2010 | Whitehurst et al. |
7783353 | August 2010 | Libbus et al. |
7785262 | August 2010 | Melker et al. |
7787959 | August 2010 | Morgan |
7792590 | September 2010 | Pianca et al. |
7797050 | September 2010 | Libbus et al. |
7797057 | September 2010 | Harris |
7797058 | September 2010 | Mrva et al. |
7805195 | September 2010 | Zealear |
7809442 | October 2010 | Bolea et al. |
7813797 | October 2010 | Bardy et al. |
7813802 | October 2010 | Tcheng et al. |
7813809 | October 2010 | Strother et al. |
7818063 | October 2010 | Wallace et al. |
7822486 | October 2010 | Foster et al. |
2001/0010010 | July 2001 | Richmond et al. |
2001/0031929 | October 2001 | O'Toole |
2002/0010495 | January 2002 | Freed et al. |
2002/0049479 | April 2002 | Pitts |
2002/0092527 | July 2002 | Wood |
2002/0128700 | September 2002 | Cross |
2002/0166556 | November 2002 | Jacob |
2002/0195108 | December 2002 | Mittelstadt et al. |
2002/0195109 | December 2002 | Mittelstadt et al. |
2003/0034031 | February 2003 | Lev et al. |
2003/0083696 | May 2003 | Avital |
2003/0093128 | May 2003 | Freed et al. |
2003/0106555 | June 2003 | Tovey |
2003/0106556 | June 2003 | Alperovich et al. |
2003/0114895 | June 2003 | Gordon et al. |
2003/0114905 | June 2003 | Kuzma |
2003/0167018 | September 2003 | Wyckoff |
2003/0195571 | October 2003 | Burnes et al. |
2003/0209145 | November 2003 | Soper |
2003/0216789 | November 2003 | Deem et al. |
2004/0015204 | January 2004 | Whitehurst et al. |
2004/0020489 | February 2004 | Gillespie et al. |
2004/0049241 | March 2004 | Campos |
2004/0055603 | March 2004 | Bruce |
2004/0073272 | April 2004 | Knudson et al. |
2004/0089303 | May 2004 | Chien |
2004/0111139 | June 2004 | McCreery |
2004/0116819 | June 2004 | Alt |
2004/0162499 | August 2004 | Nagai et al. |
2004/0194784 | October 2004 | Bertrand |
2004/0215288 | October 2004 | Lee et al. |
2004/0230278 | November 2004 | Dahl et al. |
2004/0233058 | November 2004 | Dodds |
2004/0260310 | December 2004 | Harris |
2004/0261791 | December 2004 | Horian |
2005/0004610 | January 2005 | Kim et al. |
2005/0010265 | January 2005 | Fassio et al. |
2005/0038490 | February 2005 | Gross et al. |
2005/0039757 | February 2005 | Wood |
2005/0043644 | February 2005 | Stahmann et al. |
2005/0043772 | February 2005 | Stahmann et al. |
2005/0076908 | April 2005 | Lee et al. |
2005/0085865 | April 2005 | Tehrani |
2005/0085866 | April 2005 | Tehrani |
2005/0085868 | April 2005 | Tehrani et al. |
2005/0085869 | April 2005 | Tehrani et al. |
2005/0085874 | April 2005 | Davis et al. |
2005/0098176 | May 2005 | Hoffrichter |
2005/0101833 | May 2005 | Hsu et al. |
2005/0119711 | June 2005 | Cho et al. |
2005/0139216 | June 2005 | Mittelstadt et al. |
2005/0165457 | July 2005 | Benser et al. |
2005/0209513 | September 2005 | Heruth et al. |
2005/0209643 | September 2005 | Heruth et al. |
2005/0234523 | October 2005 | Levin et al. |
2005/0235992 | October 2005 | Djupesland |
2005/0240241 | October 2005 | Yun et al. |
2005/0251216 | November 2005 | Hill et al. |
2005/0261747 | November 2005 | Schuler et al. |
2005/0267380 | December 2005 | Poezevara |
2005/0267547 | December 2005 | Knudson et al. |
2005/0277844 | December 2005 | Strother et al. |
2005/0277999 | December 2005 | Strother et al. |
2005/0278000 | December 2005 | Strother et al. |
2006/0005842 | January 2006 | Rashad et al. |
2006/0025828 | February 2006 | Armstrong et al. |
2006/0030919 | February 2006 | Mrva et al. |
2006/0032497 | February 2006 | Doshi |
2006/0052836 | March 2006 | Kim et al. |
2006/0058588 | March 2006 | Zdeblick |
2006/0058852 | March 2006 | Koh et al. |
2006/0064029 | March 2006 | Arad |
2006/0064138 | March 2006 | Velasco et al. |
2006/0079802 | April 2006 | Jensen et al. |
2006/0095088 | May 2006 | De Ridder |
2006/0111755 | May 2006 | Stone et al. |
2006/0116739 | June 2006 | Betser et al. |
2006/0129189 | June 2006 | George et al. |
2006/0135886 | June 2006 | Lippert et al. |
2006/0136024 | June 2006 | Cohen et al. |
2006/0142815 | June 2006 | Tehrani et al. |
2006/0144398 | July 2006 | Doshi et al. |
2006/0150978 | July 2006 | Doshi et al. |
2006/0150979 | July 2006 | Doshi et al. |
2006/0150980 | July 2006 | Kim |
2006/0167497 | July 2006 | Armstrong et al. |
2006/0184204 | August 2006 | He |
2006/0195170 | August 2006 | Cohen et al. |
2006/0211951 | September 2006 | Milijasevic et al. |
2006/0224209 | October 2006 | Meyer |
2006/0224211 | October 2006 | Durand |
2006/0241506 | October 2006 | Melker et al. |
2006/0241708 | October 2006 | Boute |
2006/0247729 | November 2006 | Tehrani et al. |
2006/0259079 | November 2006 | King |
2006/0264777 | November 2006 | Drew |
2006/0266369 | November 2006 | Atkinson et al. |
2006/0271118 | November 2006 | Libbus et al. |
2006/0271137 | November 2006 | Stanton-Hicks |
2006/0282127 | December 2006 | Zealear |
2006/0293720 | December 2006 | DiLorenzo |
2006/0293723 | December 2006 | Whitehurst et al. |
2007/0021785 | January 2007 | Inman et al. |
2007/0027482 | February 2007 | Parnis et al. |
2007/0038265 | February 2007 | Tcheng et al. |
2007/0043411 | February 2007 | Foster et al. |
2007/0095347 | May 2007 | Lampotang et al. |
2007/0125379 | June 2007 | Pierro et al. |
2007/0175478 | August 2007 | Brunst |
2007/0227542 | October 2007 | Kashmakov et al. |
2007/0277832 | December 2007 | Doshi et al. |
2007/0283692 | December 2007 | Tetsuka et al. |
2007/0283962 | December 2007 | Doshi et al. |
2007/0295338 | December 2007 | Loomas et al. |
2008/0023007 | January 2008 | Dolezal et al. |
2008/0027480 | January 2008 | van der Burg et al. |
2008/0041373 | February 2008 | Doshi et al. |
2008/0163875 | July 2008 | Aarestad et al. |
2008/0183254 | July 2008 | Bly et al. |
2009/0270707 | October 2009 | Alfoqaha et al. |
2009/0276024 | November 2009 | Bonde et al. |
2009/0308395 | December 2009 | Lee et al. |
2009/0318986 | December 2009 | Alo et al. |
2009/0326408 | December 2009 | Moon et al. |
2010/0016749 | January 2010 | Atsma et al. |
2010/0036285 | February 2010 | Govari et al. |
2010/0047376 | February 2010 | Imbeau et al. |
2010/0076536 | March 2010 | Merz et al. |
2010/0094379 | April 2010 | Meadows et al. |
2010/0100150 | April 2010 | Kirby et al. |
2010/0125310 | May 2010 | Wilson et al. |
2010/0131029 | May 2010 | Durand et al. |
2010/0137931 | June 2010 | Hopper et al. |
2010/0137949 | June 2010 | Mazgalev et al. |
2010/0137956 | June 2010 | Osypka et al. |
2010/0152553 | June 2010 | Ujhazy et al. |
2010/0174341 | July 2010 | Bolea et al. |
2010/0228133 | September 2010 | Averina et al. |
2010/0228317 | September 2010 | Libbus et al. |
2010/0241207 | September 2010 | Bluger |
2010/0257729 | October 2010 | Alexander et al. |
2010/0262209 | October 2010 | King et al. |
0 892 926 | Jun 2002 | EP | |||
0 900 102 | Jul 2004 | EP | |||
1 854 494 | Nov 2007 | EP | |||
53118893 | Oct 1978 | JP | |||
9-294819 | Nov 1997 | JP | |||
2000-506601 | May 2000 | JP | |||
2000-508562 | Jul 2000 | JP | |||
2003-305135 | Oct 2003 | JP | |||
2004-508908 | Mar 2004 | JP | |||
2004-532707 | Oct 2004 | JP | |||
3688301 | Jun 2005 | JP | |||
2005-521485 | Jul 2005 | JP | |||
2007-21156 | Feb 2007 | JP | |||
WO 98/20938 | May 1998 | WO | |||
WO 02/24279 | Mar 2002 | WO | |||
WO 03/000133 | Jan 2003 | WO | |||
WO 03/000347 | Jan 2003 | WO | |||
WO 03/082393 | Oct 2003 | WO | |||
WO 2005/004993 | Jan 2005 | WO | |||
WO 2006/045251 | May 2006 | WO | |||
WO 2006/063339 | Jun 2006 | WO | |||
WO 2007/134458 | Nov 2007 | WO | |||
Spence et al., "High-flow nasal cannula as a device to provide continuous positive airway pressure in infants," Journal of Perinatology, Dec. 2007, pp. 772-775, vol. 27 (12), Nature Publishing Group. cited by applicant . Kirkness et al., "Nasal airflow dynamics: mechanisms and responses associated with an external nasal dilator strip," University of Western Sydney, T.C. Amis School of Science, Department of Respiratory Medicine, Westmead Hospital and University of Sydney, Westmead, Australia, 2000. cited by applicant . De Almeida et al., "Nasal pressure recordings to detect obstructive sleep apnea," Sleep and Breathing, Feb. 25, 2006, pp. 62-69, vol. 10 (2), Springer Heidelberg. cited by applicant . Saslow et al., "Work of breathing using high-flow nasal cannula in preterm infants," Journal of Perinatology, May 11, 2006, pp. 476-480, vol. 26 (8), Nature Publishing Group. cited by applicant . Campbell et al., "Nasal Continuous positive airway pressure from high flow cannula versus Infant Flow for preterm infants," Journal of Perinatology, Jul. 2006, pp. 546-549, vol. 26 (9), Nature Publishing Group. cited by applicant . Trevisanuto et al., "A new device for administration of continuous positive airway pressure in preterm infants: comparison with a standard nasal CPAP continuous positive airway pressure system", Intensive Care Medicine, Apr. 2005, pp. 859-864, vol. 31 (6), Springer-Verlag. cited by applicant . Verse et al., "New developments in the therapy of obstructive sleep apnea," European Archives of Oto-Rhino-Laryngology, Jan. 2001, pp. 31-37, vol. 258 (1), Springer-Verlag. cited by applicant . Paquereau et al., "Positive pressure titration in the treatment of obstructive sleep apnea syndrome using continuous airway positive pressure," Revue Des Maladies Respiratoires, Apr. 2000, pp. 459-465, vol. 17 (2), Masson Editeur. cited by applicant . Mahadevia et al., "Effects of expiratory positive airway pressure on sleep-induced respiratory abnormalities in patients with hypersomnia-sleep apnea syndrome," Am. Rev. Respir. Dis., Feb. 1983, vol. 128, pp. 708-711. cited by applicant . Tiran et al., "An Improved Device for Posterior Rhinomanometry to Measure Nasal Resistance," Journal of Biomechnical Engineering, Nov. 2005, vol. 127, pp. 994-997. cited by applicant . Noseda et al., "Compliance with nasal continuous positive airway pressure assessed with a pressure monitor: pattern of use and influence of sleep habits," Chest Clinics and Sleep Laboratories, Hopitaux Erasme et Brugmann, Universite Libre de Bruxelles, Brussels, Belgium, 2000, vol. 94, pp. 76-81. cited by applicant . Goding Jr. et al., "Relief of Upper Airway Obstruction With Hypoglossal Nerve Stimulation in the Canine," The Laryngoscope, Feb. 1998, pp. 162-169, vol. 108, Lippincott-Raven Publishers, U.S.A. cited by applicant . Sahin et al., "Chronic recordings of hypoglossal nerve activity in a dog model of upper airway obstruction," Journal of Applied Physiology 87(6), 1999, The American Physiological Society, pp. 2197-2206. cited by applicant . Ferguson et al., "Effect of Mandibular and Tongue Protrusion on Upper Airway Size During Wakefulness," American Journal of Respiratory and Critical Care Medicine, 1997, pp. 1748-1754, vol. 155. cited by applicant . Isono et al., "Interaction of cross-sectional area, driving pressure, and airflow of passive velopharynx," American Physiological Society, 1997, pp. 851-859, vol. 83. cited by applicant . Oliven et al., "Effect of genioglossus contraction on pharyngeal lumen and airflow in sleep apnoea patients," European Respiratory Journal, 2007, pp. 748-758, vol. 30, No. 4. cited by applicant. |
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