U.S. patent number 3,923,207 [Application Number 05/454,838] was granted by the patent office on 1975-12-02 for microliter syringe for dispensing small, accurately measured quantities of fluid specimens.
This patent grant is currently assigned to Jintan Terumo Co., Ltd.. Invention is credited to Tuneyoshi Kyogoku.
United States Patent |
3,923,207 |
Kyogoku |
December 2, 1975 |
Microliter syringe for dispensing small, accurately measured
quantities of fluid specimens
Abstract
A microliter syringe has a hollow guide mounted to one end of a
syringe body into which a plunger is inserted. The plunger can be
smoothly inserted into, and removed from, the syringe body through
the guide without causing any eventual bending or buckling.
Inventors: |
Kyogoku; Tuneyoshi (Fujinomiya,
JA) |
Assignee: |
Jintan Terumo Co., Ltd. (Tokyo,
JA)
|
Family
ID: |
12514408 |
Appl.
No.: |
05/454,838 |
Filed: |
March 26, 1974 |
Foreign Application Priority Data
|
|
|
|
|
Mar 29, 1973 [JA] |
|
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48-38040 |
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Current U.S.
Class: |
222/386; 604/218;
422/924; 604/207 |
Current CPC
Class: |
B01L
3/022 (20130101); A61M 5/315 (20130101); A61M
5/31531 (20130101) |
Current International
Class: |
A61M
5/315 (20060101); B01L 3/02 (20060101); G01F
011/00 () |
Field of
Search: |
;222/386
;128/218R,218P,218C,218PA,218N,218M,218A,218G,218S,221,218NV |
References Cited
[Referenced By]
U.S. Patent Documents
Foreign Patent Documents
Primary Examiner: Knowles; Allen N.
Attorney, Agent or Firm: Bacon & Thomas
Claims
What is claimed is:
1. A microliter syringe for dispensing small, arcuately measured
quantities of fluid specimens, comprising:
a syringe body having a small bore therethrough;
a cannula mounted on one end of said body and communicating with
the said bore;
an elongated plunger of bendable material extending slidably in
said bore, the diameters of said plunger and bore being of the
order of 0.5 mm whereby said plunger is readily bendable; and
a guide means mounted on the other end of said body with said
plunger extending slidably therethrough, said guide means being
readily bendable in response to lateral forces on said plunger
outwardly of said guide whereby said guide means prevents kinking
of said plunger upon operation of said syringe with the portion of
said plunger in said bore being angularly related to the portion
thereof extending outwardly of said body.
2. A microliter syringe according to claim 1 in which said guide
means is more readily bendable at its free end portion than at its
base portion.
3. A microliter syringe according to claim 2 in which said guide
means is thinner at its free end portion than at its base
portion.
4. A microliter syringe according to claim 1 in which said guide
means is made of a flexible plastic resin.
5. A microliter syringe according to claim 1 in which said guide
means is substantially cylindrical in shape.
6. A microliter syringe according to claim 1 in which a knob is
mounted on the free end of the plunger; a flange is mounted on the
said other end of the syringe body; and wherein the distance
between the flange and the knob is sufficient for a human finger to
be inserted therebetween; and the distance between the knob and the
upper end of the guide means when the plunger is pushed down to its
limit is about 1 mm.
7. A microliter syringe according to claim 1 in which said guide
means is provided with a funnel-shaped mouth at its outer end for
guiding said plunger therethrough.
Description
This invention relates to a microliter syringe for dispensing
small, accurately measured quantities of fluid specimens, and
particularly to a microsyringe in which a plunger can be smoothly
inserted into and removed from the syringe body.
A microliter syringe as used in a gas chromatography analysis etc.
is adapted to dispense small quantities of medicament and a
stainless wire of, for example, 0.5 mm in diameter is used as a
plunger for the syringe. When this plunger is inserted into a
syringe, it is liable to buckle. To prevent such buckling, a
variety of proposals has been made to this date. However,
microliter syringes of the prior art are rather elaborate in design
to avoid such buckling.
Furthermore, the syringe is required to have such a construction as
is easily cleaned for repeated use, and any complicated
construction is therefore undesirable, since a delicate operation
is carried out.
It is accordingly the object of this invention to provide an easily
cleanable microliter syringe of simple construction, in which a
plunger is smoothly inserted into and removed from a syringe body
through a hollow guide without causing any buckling.
According to this invention there is provided a microsyringe
comprising a syringe body having an inner bore for permitting
liquid to be inserted along its axial direction; a cannula mounted
to one end of the syringe body and communicating with the inner
bore of the syringe body; a flexible hollow guide mounted to the
other end of the syringe body and communicating with the inner bore
of the syringe body; and a plunger adapted to be slidably
reciprocated within the bore of the hollow guide and the bore of
the syringe body.
This invention can be more fully understood from the following
detailed description when taken in conjunction with the
accompanying drawing, in which:
FIG. 1 is a side view showing a microliter syringe according to
this invention;
FIG. 2 is a cross-sectional view, partly broken away, showing an
upper section of the microliter syringe of FIG. 1;
FIGS. 3A to 3C are cross-sectional views each showing a
modification of a hollow guide for the microliter syringe according
to this invention;
FIG. 4 is a cross-sectional view, partly broken away, showing the
manner in which a plunger is inserted slantwise into a syringe body
through a guide; and
FIG. 5 is a cross-sectional view, partly broken away, showing the
manner in which a plunger is inserted slantwise into a syringe
body, wherein a flexible hollow guide is not employed.
This invention will be further explained by reference to the
accompanying drawing.
In FIG. 1 there is shown a syringe body 1 made of a cylindrical,
thick-walled transparent glass. In the central portion of the
syringe body is provided an axially penetrating inner bore 2 into
which liquid can be introduced. A cannula 3 is mounted to one end
of the syringe body 1 so as to communicate with the inner bore 2. A
scale 4 for indicating an amount of liquid is marked on the outer
surface of the syringe body 1. To the other end of the syringe body
a flange 5 is mounted to permit a plunger 8 to be easily
reciprocated. In the flange 5 a mounting hole 6 is provided
coaxially with the inner bore and a hollow guide 7 can be
detachably fitted into the mounting hole. The hollow guide 7 is
made of either plastic resin such as fluorine resin etc. or a
flexible material such as glass fiber etc. and is substantialy
cylindrical in shape. The guide is larger in outer diameter at its
base end portion than at its free end portion. As a result, the
guide is more flexible at its free end portion than at its base end
portion. As shown in FIG. 2, a rib 6' is provided short of the base
end of the guide. The rib is snap-fitted into a groove provided in
the inner surface of the mounting hole 6. The rib may be provided
on the inner surface of the mounting hole and, in this case, the
associated groove is provided in the outer surface of the guide.
The guide 7 can be easily snap-fitted into the flange 5 by merely
pushing the former into the hole of the latter and it can be easily
removed from the flange by merely pulling the guide relative to the
flange. The guide 7 may be detachably screw-threaded into the
flange. Any detachable arrangement may be adopted in this case.
The plunger 8 is made of a stainless steel having an outer diameter
of, for example, 0.5 mm and is intimately insertible into the bore
of the guide 7 and the inner bore of the syringe body. A knob 10 is
mounted at the top of the plunger 8. It is preferred that a length
l.sub.1 between the knob 10 and the top end of the guide 7, which
is defined when the plunger 8 is pushed down to its limit i.e. the
forward end of the plunger 8 is abutted against the penetrating end
of the cannula 3 to indicate a zero position on the scale, be not
more than several millimeters or preferably of the order of 1 mm. A
length l.sub.2 between the upper end surface of the flange 5 and
the lower end surface of the knob is preferably at least sufficient
for a human finger to be inserted therebetween. The hollow guide 7
may take a variety of forms as shown in FIGS. 3A, 3B and 3C. The
guide shown in FIG. 3A takes a cylindrical form. The guide shown in
FIG. 3B takes a frusto-conical form and, therefore, pliability is
increased toward the top of the frusto-conical guide. The guide
shown in FIG. 3C is similar in shape to that shown in FIGS. 1-2 and
the mouth of the guide is funnel-shaped, permitting an easy
insertion of the plunger as well as preventing buckling of the
plunger.
According to a microliter syringe so constructed, even if during
the insertion of the plunger 8 into the guide the plunger is
displaced slantwise as shown in FIG. 4, the guide is pliably bent
at a flexible section 9 and the plunger 8 can be smoothly pushed
into the bore of the syringe body without any appreciable
resistance. Furthermore, even if the plunger is pliably bent, the
guide is correspondingly bent so that the plunger does not buckle.
And any tendency for the plunger to be eventually bent can also be
avoided due to the pliable or flexible nature of the hollow
guide.
When the plunger is manually pushed down to the zero position on
the scale and abutted against the penetrating end of the cannula, a
manual depressing force is concentrated on the exposed portion of
the plunger. Since, however, the length l.sub.1 so defined between
the upper end surface of the plunger and the lower end surface of
the knob is not more than several millimeters or preferably of the
order of about 1 mm, the plunger does not buckle even if any slant
force is applied to the plunger. If any guide is not mounted to the
syringe body through the flange, a space necessary for a manual
operation is required between the flange 5 and the knob 10 and,
consequently, the exposed surface of the plunger as defined between
the flange and the knob is made longer. In this case, if further
manual depressing force is applied to the knob, the plunger tends
to be eventually bent or buckle at the upper end surface of the
flange 5. According to this invention, a length between the knob 10
and the guide 7 can be reduced to about 1 mm and a resistance to
buckling is further increased. Furthermore, any eventual bending or
plastic deformation as well as buckling of the plunger can be
avoided due to the pliable section 9 of the guide.
The plunger 8 and guide 7 can be, after removal from the syringe
body, cleaned separately. The guide is easy to handle during
cleaning, since it is detachably mounted to the syringe body
through the flange.
As explained above, according to this invention the flexible or
pliable guide is mounted to the syringe body. This arrangement can
prevent any eventual bending or buckling of the plunger as
occurring when the plunger is inserted into the syringe body and
even when the insertion is nearly completed. Furthermore, the
arrangement provides a longer space between the flange and the knob
due to the presence of the guide so that the plunger can be easily
manipulated. As the hollow guide is simple in construction and is
removably mounted, for example, through the flange, to the syringe
body, a cleaning operation can be easily carried out. Consequently,
practical advantages are obtained according to this invention.
It is to be noted that the guide can be fixedly secured to the
syringe body if circumstances permit.
* * * * *