U.S. patent number 3,921,637 [Application Number 05/490,469] was granted by the patent office on 1975-11-25 for inhaler for powdered medicament.
This patent grant is currently assigned to Bespak Industries Limited. Invention is credited to Annette Bennie, Norman Leonard Reed.
United States Patent |
3,921,637 |
Bennie , et al. |
November 25, 1975 |
Inhaler for powdered medicament
Abstract
An inhaler for powdered medicaments comprises a housing having a
chamber for receiving a capsule containing a dose of the medicament
to be dispensed. A duct in the housing has one end open to the
atmosphere and the other end of the duct has its outlet in a
mouthpiece which may be inserted into the mouth of a user. A
passage connects the chamber to the duct and there is a manually
operated pump for supplying air under pressure to the chamber. A
flow sensor is arranged in the duct and there is a valve to prevent
air under pressure and the medicament from entering the duct as
well as means to operate the valve to allow air and medicament to
enter the duct when the flow sensor detects a user inhaling through
the duct. The valve is situated between the pump and the chamber,
and the capsule and the chamber are so arranged and dimensioned
that all the air supplied by the pump flows through the capsule
when the valve is opened.
Inventors: |
Bennie; Annette (Benoni,
ZA), Reed; Norman Leonard (Waltham Cross,
EN) |
Assignee: |
Bespak Industries Limited
(EN)
|
Family
ID: |
10372655 |
Appl.
No.: |
05/490,469 |
Filed: |
July 22, 1974 |
Foreign Application Priority Data
|
|
|
|
|
Jul 23, 1973 [UK] |
|
|
35003/73 |
|
Current U.S.
Class: |
128/203.15 |
Current CPC
Class: |
A61M
15/0028 (20130101); A61M 15/0033 (20140204); A61M
15/0025 (20140204); A61M 15/00 (20130101); A61M
15/0091 (20130101); A61M 2202/064 (20130101); A61M
15/0095 (20140204) |
Current International
Class: |
A61M
15/00 (20060101); A61l 009/00 () |
Field of
Search: |
;128/265,266,208,197,209,210 ;222/556 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Knowle; Allen N.
Assistant Examiner: Stack, Jr.; Norman L.
Attorney, Agent or Firm: Browne, Beveridge, DeGrandi &
Kline
Claims
We claim:
1. An inhaler for powdered medicaments comprising a housing,
a chamber in the housing;
a capsule containing a dose of the medicament to be dispensed, said
capsule being located in the chamber;
a duct in the housing, one end of the duct being open to the
atmosphere and the other end of the duct having its outlet in a
mouthpiece for insertion into the mouth of a user;
an outlet passage connecting the chamber to the duct;
manually operated pump means for supplying air under pressure to
the chamber;
an inlet passage means connecting the pump means to the chamber to
carry all of the air supplied by the pump means into the
capsule;
2. An inhaler as claimed in claim 1 in which the flow sensor
comprises a movable vane mounted in the duct.
valve means situated between the pump means and the chamber in the
inlet passage for preventing air under pressure and medicament from
entering the duct;
a flow sensor arranged in the duct; and
said valve means being operable to open in response to the flow
sensor means to allow air under pressure and medicament to enter
the duct when the flow sensor detects a user inhaling through the
duct.
3. An inhaler for powdered medicaments comprising a housing having
a chamber for receiving a capsule containing a dose of the
medicament to be dispensed, a duct in the housing, one end of the
duct being open to the atmosphere and the other end of the duct
having its outlet in a mouth piece for insertion into the mouth of
a user, a passage connecting the chamber to the duct, manually
operated pump means for supplying air under pressure to the
chamber, a vane pivotally mounted in the duct, and valve means to
prevent air under pressure and the medicament from entering the
duct, the valve means being arranged on a lever rigidly connected
to the vane to allow air and medicament to enter the duct when the
vane detects a user inhaling through the duct, in which applicator
the valve means is situated between the pump means and the chamber,
and the capsule and the chamber are so arranged and dimensioned
that all the air supplied by the pump means flows through the
capsule when the valve means is opened.
4. An inhaler as claimed in claim 3 in which the vane pivots about
a hinge between the lever and the duct, the hinge being adjacent
the valve means.
5. An inhaler as claimed in claim 3 in which the valve means is
spring urged into the closed position.
6. An inhaler as claimed in claim 3 in which the chamber is adapted
to receive a sealed capsule containing the medicament and means are
provided to puncture the ends of the capsule.
7. An inhaler as claimed in claim 6 in which a pin controlled by a
sliding member mounted externally of the housing is provided to
pierce one end of the capsule.
8. An inhaler as claimed in claim 7 in which a cover is provided
for closing the mouth piece when not in use, the cover being
provided with an internally mounted pin to pierce the other end of
the capsule.
Description
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to an inhaler for powdered medicaments and is
particularly useful in applying powdered medicaments for the relief
of respiratory ailments such as asthma.
2. Description of the Prior Art
Such devices are known, for example, from U.S. Pat. No. 3,155,573
(Fowler) which describes a device in which powdered medicament is
entrained in a stream of air under pressure, a valve being opened
to allow the stream of air and medicament to be released from the
device when a user inhales through a mouthpiece.
SUMMARY OF THE INVENTION
It is an object of this invention to provide an improved device of
this type.
Accordingly the invention provides an inhaler for powdered
medicaments comprising a housing having a chamber for receiving a
capsule containing a dose of the medicament to be dispensed, a duct
in the housing, one end of the duct being open to the atmosphere
and the other end of the duct having its outlet in a mouth piece
for insertion into the mouth of a user, a passage connecting the
chamber to the duct, manually operated pump means for supplying air
under pressure to the chamber, a flow sensor arranged in the duct,
and valve means to prevent air under pressure and the medicament
from entering the duct and means to operate the valve means to
allow air and medicament to enter the duct when the flow sensor
detects a user inhaling through the duct, in which inhaler the
valve means is situated between the pump means and the chamber, and
the capsule and the chamber are so arranged and dimensioned that
all the air supplied by the pump means flows through the capsule
when the valve means is opened.
An advantage of this arrangement is that a very high proportion of
the medicament contained in the capsule is administered to the user
during one actuation of the device.
In a preferred embodiment, the flow sensor comprises a vane mounted
in the duct for pivotal movement and the valve means is mounted on
a lever rigidly attached to the vane.
In this case, the vane may pivot about a hinge between the lever
and the duct, and the hinge may be adjacent the valve means.
Further, the valve means may be spring urged into the closed
position.
An advantage of this preferred arrangement is that the user
receives the dose of medicament at the correct point in the
inspiratory cycle and this ensures that the inhaled drug is most
efficiently utilised.
Preferably the chamber is adpated to receive a sealed capsule
containing the medicament and there may be means to puncture the
ends of the capsule.
A pin controlled by a sliding member may be provided to pierce one
end of the capsule.
There may be a cover for the mouth piece and the cover may be
provided with means to pierce the other end of the capsule.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a vertical section through the inhaler;
Fig. 2 is a horizontal section taken on the line 2--2 of FIG. 1;
and
FIG. 3 is a plan view of the inhaler.
DESCRIPTION OF THE PREFERRED EMBODIMENT
The inhaler comprises a housing 10 in which is formed a cylinder
11. A bellows 12 is mounted in the cylinder 11 and a non-return
valve 13 is provided in the wall of the cylinder 11 to allow
ingress of air to the bellows.
At the lower end of the cylinder 11 there is formed a block 14
which is recessed to house one end of a capsule 15 containing the
powdered medicament to be dispensed. The capsule is held in
position by means of a retaining member 16 which has a
corresponding recess and which is attached by spokes 35 to a
mouthpiece 17 which screws on to the housing.
Air will flow from the cylinder 11 to the capsule 15 by means of a
passage 18 in the block and then through an inlet passage 19 also
in the block. A valve 20 is provided to close off the lower end of
the passage 18 in a manner which will be described later.
In order to puncture the ends of the capsule 15 two needles 21 and
22 are provided. The needle 21 is formed as part of a cover 23 for
the mouth piece and passes into the capsule through an outlet 24
from the capsule to the mouth piece. The needle 22 is mounted on a
button 25 which is carried by a connecting arm 27 which passes
through a slot 28 in the housing and is rigidly attached to a
sliding member 29. The member 29 can be moved along the side of the
housing to press the button 25 inwardly against a spring 26 in
order to puncture the capsule.
The valve 20 is mounted at one end of a vane 30 pivoted about a
fulcrum 31. A spring 32 is provided which biasses the valve 20 to
close the passageway 18 (FIG. 1 shows the vane in solid lines in
its position where the valve is open and in broken lines in its
position where the valve is closed).
The vane 30 is situated in an air duct having its inlet in the
region 33 in FIG. 1 and having its outlet through holes in the
retaining member 16 leading into the mouth piece.
In order to operate the inhaler a capsule 15 is first placed in
position and the two ends of the capsule are punctured, first using
the needle 21 and then the needle 22. The cover 23 is then removed.
Pressure is then applied to the top of the bellows 12 to provide a
supply of air under pressure while the valve 20 is closed because
of the action of the spring 32. When the user inhales air through
the mouth piece 17 flow of air through the duct from the region 33
to the mouth piece moves the vane 30 into the position shown in
solid lines in FIG. 1 thus releasing the air under pressure to flow
through the capsule 15 and out into the mouth piece taking with it
the medicament in the capsule. In this way a thorough purge of the
capsule is ensured and the dose of medicament is inhaled by the
user. A typical result for the amount of medicament inhaled by the
user is 91% of the medicament contained in the capsule.
* * * * *