U.S. patent number 3,915,151 [Application Number 05/454,557] was granted by the patent office on 1975-10-28 for apparatus for promoting healing processes.
Invention is credited to Werner Kraus.
United States Patent |
3,915,151 |
Kraus |
October 28, 1975 |
Apparatus for promoting healing processes
Abstract
An apparatus for promoting healing of body tissue composed of a
coil arranged to be applied to the affected body part and to be
connected to a low frequency a.c. source to produce a magnetic
field within the region to be treated, and at least two sheet-like
electrodes associated with the coil and spaced from one another,
the electrodes being arranged to be located at respectively
opposite sides of the region to be treated and to be connected to a
source of a low frequency voltage to produce an electric field
within the region to be treated at the same time as the magnetic
field.
Inventors: |
Kraus; Werner (Munich,
DT) |
Family
ID: |
5875716 |
Appl.
No.: |
05/454,557 |
Filed: |
March 25, 1974 |
Foreign Application Priority Data
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Mar 23, 1973 [DT] |
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2314573 |
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Current U.S.
Class: |
600/13; 607/51;
607/3 |
Current CPC
Class: |
A61B
17/58 (20130101); A61N 2/002 (20130101); A61N
1/40 (20130101); A61N 2/02 (20130101); A61N
2/004 (20130101) |
Current International
Class: |
A61B
17/58 (20060101); A61N 1/40 (20060101); A61N
2/00 (20060101); A61N 001/42 () |
Field of
Search: |
;128/1.5,404,405,411,419PF,419R,42A,421,422,423,82.1,1C |
References Cited
[Referenced By]
U.S. Patent Documents
Foreign Patent Documents
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871,672 |
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Jun 1961 |
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GB |
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2,116,869 |
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Oct 1971 |
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DT |
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1,109,280 |
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Jun 1961 |
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DT |
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Other References
Cochran, "Bulletin of the New York Academy of Medicine" Vol. 48,
No. 7, Aug. 1972, pp. 899-911..
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Primary Examiner: Kamm; William E.
Attorney, Agent or Firm: Spencer & Kaye
Claims
What I claim is:
1. In apparatus for promoting healing processes and comprising a
coil adapted to be applied to a part of the body to be treated and
adapted to be connected with a source for a varying current with a
low frequency for causing the coil to produce a corresponding
magnetic field in the longitudinal direction of and which pervades
the part of the body to be treated, the improvement comprising two
sheet-like electrodes associated with said coil, disposed with a
spacing between them and arranged to be connected with a source of
low frequency varying voltage for producing an electric field which
pervades the part of the body to be treated simultaneously with the
magnetic field, said electrodes extending at least approximately
parallel to the surface occupied by the windings of the coil.
2. An apparatus in accordance with claim 1 wherein the coil is
composed of a number of flat coils connected to each other in a
jointed manner, with at least two of said coils being provided with
a respective one of said sheet-like electrodes.
3. An apparatus in accordance with claim 1 further comprising a
rod-shaped body of a tissue-compatible insulating material, and a
receiving coil carried by said body, and wherein said two
electrodes are electrically connected to said receiving coil and
extend adjacent to the surface of said body.
4. An apparatus in accordance with claim 3 wherein said electrodes
are provided with an insulating surface.
5. In apparatus for promoting healing processes and comprising a
coil adapted to be applied to a part of the body to be treated and
adapted to be connected with a source for a varying current with a
low frequency for causing the coil to produce a corresponding
magnetic field, which pervades the part of the body to be treated,
the improvement comprising two insulated sheet-like electrodes,
disposed with a spacing between them and arranged to be connected
with a source of low frequency varying voltage for producing an
electric field which pervades the part of the body to be treated
simultaneously with the magnetic field, a bone splint implantate
member; a receiving coil arranged on such implantate member and
magnetically linked to said first-recited coil, said receiving coil
having terminals each connected to a respective one of said two
insulated sheet-like electrodes and constituting said source of
voltage.
Description
BACKGROUND OF THE INVENTION
The present invention relates to an apparatus for promoting healing
processes of the type including a coil adapted to be applied to a
part of the body to be treated and which is adapted to be connected
with a source for a varying current with a low frequency and makes
it possible to produce a corresponding magnetic field, which
pervades the part of the body to be treated.
The German Pat. Specification (Patentschrift) No. 1,918,299,
corresponding to my U.S. Pat. No. 3,745,995, and the German Patent
Specification (Offenlegungsschrift) No. 2,115,869, corresponding to
my pending U.S. application Ser. No. 241,727, filed April 6, 1972,
and also the Munchner Medizinische Wochenschrift 42 (1972), pages
1814 to 1819 refer to the promotion of healing of fractured bones
by a low frequency AC pervading the injured bone zone galvanically.
The AC has preferably a frequency below 100 Hz and a curve form
without steep leading and trailing flanks.
The AC prevading the injured bone zone can be induced by an
implanted receiving coil, provided with corresponding electrodes,
using a magnetic field, which is produced by a coil which is
applied to the part of the body to be treated and is connected with
a suitable AC generator.
Furthermore, the above-mentioned German Pat. Specification No.
2,116,869 refers to the fact that the influence of a suitably
directed low frequency magnetic alternating field alone leads to an
encouragement of healing processes and to enhanced vascularisation
(formation of blood vessels).
SUMMARY OF THE INVENTION
One aim of the present invention is that of creating an apparatus
which makes possible a still more pronounced encouragement of
healing processes than the above-mentioned forms of apparatus.
This aim is to be achieved in accordance with the invention by an
apparatus of the above-mentioned type which is characterised in
that the coil is provided with two sheetlike electrodes which are
arranged with a spacing between them and are adapted to be
connected with a source of low frequency varying voltage for the
production of an electric field which pervades the part of the body
to be treated simultaneously with the magnetic field.
It has thus been found that the regeneration of damaged bone and
soft tissue can be substantially promoted by the simultaneous
application of slowly varying electricl and magnetic fields,
preferably with approximately the same strength.
The sheet-like electrodes are electrically insulated from the part
of the body to be treated or are so arranged at a distance from it
that through the body part to be treated there flows no galvanic
conduction current and instead only the displacement and
polarisation current flows through the part of the body, this
current being produced by the electric field between the sheet-like
electrodes arranged like the plates of a capacitor.
Further developments and forms of the invention are defined in the
subordinate claims.
An important feature of the invention resides in that the electric
and magnetic fields, preferably having approximately the same
energy content, vary with the same frequency but are shifted in
phase relative to each other, the phase shift being approximately
about 90.degree..
In what follows, embodiments of the invention will be described
with reference to the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a diagrammatic representation of an apparatus in
accordance with a first embodiment of the invention, which is
especially suitable for treating extremities of the human body.
FIG. 2 is a diagrammatic representation of a second embodiment of
the invention.
FIG. 3a is a diagrammatic view of a third embodiment of the
invention.
FIG. 3b shows an enlarged cross-section through a marrow pin
belonging to the apparatus in accordance with FIG. 3a.
FIG. 4 shows a view similar to FIG. 3a of a further embodiment of
the invention.
FIGS. 5 and 6 show partly sectioned views of further embodiments of
the invention.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
The embodiment of the invention shown in FIG. 1 comprises a
substantially cylindrical coil 10 (solenoid coil), which can be
slid over the extremity, for example a leg 12 indicated in broken
lines, to be treated. On the inner wall of the coil 10, on opposite
sides, two electrodes 14 are arranged, which each consist for
example of a thin metal sheet material, and are provided with
insulation, not shown, which prevents galvanic or conductive
contact between the electrodes 14 and the leg 12 to be treated, or
another part of the body. The coil 10 and the electrodes 14 are
connected respectively with wires 16, only indicated
diagrammatically, leading to an electrical function generator 18,
which supplies a current for the supply of the coil 10 and a
voltage for supply of the electrodes 14.
The current supplied to the coil 10 can be a symmetrical or
asymmetrical AC or DC with superimposed AC components or it can be
a pulsating current. The frequency of the AC or of the AC component
of the coil current produced by the function generator 18 is
preferably adjustable and lies in the range of 1 to 100 Hz for
example and preferably between approximately 5 and 30 Hz. The
oscillation form of the AC or AC component respectively is
preferably relatively low in harmonics (for example less than 20%
or 10% harmonics). The leading and trailing flanks of the AC half
cycles should not be abrupt and instead should be gradual.
Therefore, in contrast to a sinusoidal or triangular wave current a
square wave current is undesired.
The function generator preferably comprises means for producing
current characteristics or functions which are copied from
physiological variations in the human body, for example the course
of the movement of the ribs during breathing, the pressure
characteristic or function in the lungs or the course of the pulse
wave form, and more particularly the systol or a healthy, normal
person.
Much the same applies for the voltage which is supplied by the
function generator 18 to the electrodes 14.
Electrical circuit arrangments for the supply of voltages and
currents of a complicated wave form are described in the book
"Waveforms" Radiation Laboratory Series, McGRaw-Hill, New York,
1949 for example. Voltage and current functions copied from
physiological functions can be produced for example by using
suitably constructed sensors applied to the body and using
amplifier circuits for the supply of the coils and electrodes
respectively with the required current strength or voltage
respectively. Finally, also signals of the desired shape can be
stored on a loop of magnetic tape, which is then played back with a
suitable speed and the played back signals are amplified in the
manner required for supply of the coil and the electrodes
respectively.
The amplitudes of the AC current and voltage are preferably
adjustable and preferably have such values that the energy content
of the magnetic field pervading the part of the body treated and
the energy content of the electric field simultaneously pervading
the treatd part of the body are at least approximately the same.
The magnetic field strength in tissue can lie for example between
20 and 200 Gauss, while the electrical field strength for the
treatment of tissue regions close to the electrodes can amount to
approximately 0.1 V/cm to approximately 1 V/cm. For the treatment
of deeper regions or parts of the body it is also possible to
operate with substantially higher field strengths.
The function generator 18 can comprise setting members for
simultaneous and independent variation of the amplitudes of the AC
voltage and of the AC current.
Preferably the function generator 18 furthermore comprises a device
which makes it possible to adjust the phase position between the AC
current and the AC voltage. Preferably the AC current and the AC
voltagbe and, respectively, the AC current and the AC voltage
components of the current supply to the coil 10 and of the voltage
applied to the electrodes 14 have a phase shift of approximately
90.degree..
The coil 10 and the electrodes 14 associated with it are preferably
so constructed that the magnetic field lines diagrammatically shown
are substantially parallel to the principal direction of the flow
of blood in the part of the body treated or, respectively, in the
longitudinal direction of an extremity being treated. The
electrical fields should, on the other hand, be approximately
perpendicular to the magnetic fields and therefore be generally
perpendicular to the physiological orientation, for example the
direction of the fibers in the bone.
The device or apparatus in accordance with FIG. 1 is especially
suitable for encouraging the healing of closed bone fractures, in
the case of which the repositioning fixation of the parts of the
fractured bone in relation to each other) is not carried out by an
operation and instead is brought about by external fixing with
plaster. In the case of such fractures the duration of healing and
therefore the danger of atrophic interference, more particularly in
the case of older persons, can be substantially reduced.
FIG. 2 shows an embodiment of the invention with a magnetic coil
arrangement 10', which comprises a number of flat coils 10a to 10f,
which can be regarded as flattened cylinder coils and are
connected, at their longitudinal edges running parallel to the axis
of coiling, with each other in a jointed manner so that they can be
applied for example externally to the torso or head and then
produce an axial magnetic field in the respective part of the body.
The flat coils 10a to 10f are connected electrically in series and
are connected with a function generator 18, as has been explained
with reference to FIG. 1.
The side, facing in a certain direction, of each flat coil 10a to
10f carries a corresponding plate-like electrode 14a to 14f, whose
surface is provided with insulation coating which is not shown.
The electrodes, arranged on the flat coils 10a to 10c, are
connected with a lead connected with the function generator 18,
while the other lead connected with the function generator 18 is
connected with the electrodes of the flat coil 10d to 10f. The
electric and magnetic field distribution occurring in this
embodiment of the invention is shown in FIG. 2 the magnetic field
lines being represented by long broken lines and the electric field
lines being represented by short broken lines.
FIG. 3a shows in section a fractured bone 20, which has been reset
by means of a marrow nail 22. The marrow nail 22 comprises a
receiving coil 24 (FIG. 3b) of a rodshaped ferrite core, on which a
solenoid winding is arranged. In contrast to the above-mentioned
known "electro marrow nails" the ends of the receiving coil 24 are,
however, not connected with the electrodes on the surface of the
marrow nail, which are in galvanic contact with the bone to be
healed, and instead are connected with electrodes 14', whose
surfaces are insulated, so that no galvanic currents can flow
between them. The electrodes 14' can be embedded for example in the
marrow nail, which at least for this part consists of a dielectric
material.
The marrow nail 22 described is mounted as is conventional in the
injured bone 20 and the injured extremity comprising the marrow
nail 22 with the receiving coil 24 is then brought into the field
of a coil 10 placed over the injured extremity. The coil 10 is
connected with a function generator 18 of the type described with
reference to FIG. 1. The voltage induced by the magnetic field of
the coil 10 in the receiving coil 24 passes to the insulated
electrodes 14' so that in the bone zone an electrical field is
produced which runs generally perpendicularly to the magnetic
field. The coil 10 can, as has been explained with reference to
FIG. 1, additionally be provided with electrodes 14, which are
directly supplied with a voltage by the function generator 18 and
this voltage preferably has the same frequency as the AC in the
coil 10, but with respect to this voltage is shifted in amplitude
by approximately 90.degree..
In the case of the apparatus in accordance with FIG. 3 it is
naturally also the magnetic field of the receiving coil 24 which is
effective, which can therefore be regarded as an equivalent to the
coil 10.
The apparatus in accordance with FIG. 4 is similiarly constructed
to the apparatus in accordance with FIG. 3a and for components
equivalent in function the same reference numerals have been used.
In the case of FIG. 4 the fractured bone 20 is, however, not pinned
or nailed and instead, since it is a question of a closed fracture,
it is fixed by a plaster cast or the like. In the plaster,
insulated field electrodes 14 are embedded and are connected by
flexible electrical leads with the function generator. Another
possibility resides in providing windows in a plaster or plastic
cast and fixing the field electrodes in the windows acting as
frames adjacent to the surface of the extremity to be treated so
that the electrodes are separated by an air gap from the surface of
the patient. The coil 10 and the electrodes 14 are supplied by a
function generator 18' with a low frequency current or a low
frequency voltage. The function generator 18' is synchronised or
controlled in the case of this embodiment by means of a pulse
receiving means 30, that is to say in the latter case the course of
the AC or of the AC voltage corresponds to the pulse pressure wave.
he function generator 18' can as an alternative measure also be
synchronised by an electrocardiogram or controlled with respect to
the curve shape.
In the case of the apparatus in accordance with FIG. 4 the pulse
receiving means 30 can for example be a pressure sensor or a very
low frequency microphone M and the function generator 18' can
comprise the following circuit units: A pre-amplifier, whose input
is connected with the pulse receiving means 30 and whose output is
connected on the one hand directly with the input of a current
amplifier and on the other hand is connected with an adjustable
phase shifting device for connection with the input of a voltage
amplifier. The output of the current amplifier supplies the magnet
coil 10, while the output of the voltage amplifier is connected
with the electrodes 14 it being understood that in practice there
are two output leads from the voltage amplifier rather than the one
shown.
FIGS. 5 and 6 show two embodiments of the present device, which
comprise a pin-like body 32 with rounded ends, which can consist of
a fluorine carbon polymer for example. In the body there is a
substantially cylindrical shaped receiving coil 24 which can
comprise a rod-shaped magnetic core which is not especially
shown.
The ends of the receiving coil are connected respectively with two
electrodes, which are embedded in the body 32. Preferably the
surface of each electrode is insulated so that no galvanic currents
can flow from it. The electrodes 24a of the embodiment in
accordance with FIG. 5 have the shape of parts of the cylindrical
casing and are arranged on opposite sides of the body 32. The
electrodes 14b of the embodiment in accordance with FIG. 6 are
annular and arranged on the body 32 with an axial spacing.
The embodiment in accordance with FIGS. 5 and 6 can be mounted in
the marrow channel of a bone, for example in the case of
osteomyelitis, and furthermore they are suitable for producing
autologous replacement of fibers by growing round or
encapsulation.
The present apparatus is particularly suitable for encouraging
healing processes in and under closed skin, that is to say in the
case of closed fractures and also in the case of pathological
processes in tissue. The polarisation force of the electrical field
has a substantial influence on the recovery of the structure of the
damaged tissue, while the distribution of blood vessels within the
structure is directly influenced by the magnetic field. Owing to
the combination of electrical and magnetic fields the essential
conditions for regeneration of a functioning structure, that is to
say healing, are provided.
A further possiblity of influencing the biological processes in the
tissues is based in the fact that the magnetic and/or electrical
alternating field, more particularly the latter, can have DC
components superimposed on it, which may possibly be so large that
no reversal of polarity of the field occurs and instead a pulsating
field with a predetermined polarity comes into play. In this case
the function generator 18 or 18' respectively can comprise
circuitry features which make it possible to superimpose on the AC
supplied to the coil 10 DC preferably with adjustable amplitude and
if necessary adjustable polarity and/or make it possible to
superimpose on the AC voltage supplied to the electrodes 14 a DC
voltage, preferably with an adjustable amplitude and polarity.
The preferred phase shift between electrical and magnetic fields
can, however, also be produced by a delay member, possibly
adjustable, in the function generator or also by a differentiating
member, which derives AC voltage from AC supplied to the coil 10,
and whose course or shape corresponds to the differential with
respect to time of the AC current. The use of a differentiating
member for the production of the desired phase shift between the
magnetic and electrical fields is particularly suitable in the case
of the use of non-sinusoidal current or voltage shapes or
characteristics, for example when the course of the fields is to be
adapted to a biological magnitude, for example the pulse pressure
wave or systole.
* * * * *