U.S. patent number 3,903,888 [Application Number 05/450,008] was granted by the patent office on 1975-09-09 for time-delay metering dispenser.
This patent grant is currently assigned to Minnesota Mining and Manufacturing Company. Invention is credited to Joseph S. Buelow, Thomas S. Reid.
United States Patent |
3,903,888 |
Buelow , et al. |
September 9, 1975 |
**Please see images for:
( Certificate of Correction ) ** |
Time-delay metering dispenser
Abstract
A device suitable for dispensing medicament fluids in repeated
dosage amounts on a time-delay basis comprises an applicator head
and a handle having a primary first reservoir containing a quantity
of medicament fluid to be dispensed within the handle. A single
dosage containing second reservoir is contained within the
applicator head and has dispensing means in communication with the
head. A filling means positively fills the dosage reservoir from
the primary first reservoir over a predetermined delay time
generally not less than 30 minutes.
Inventors: |
Buelow; Joseph S. (Maplewood,
MN), Reid; Thomas S. (Little Canada, MN) |
Assignee: |
Minnesota Mining and Manufacturing
Company (St. Paul, MN)
|
Family
ID: |
23786383 |
Appl.
No.: |
05/450,008 |
Filed: |
March 11, 1974 |
Current U.S.
Class: |
604/186; 222/187;
401/187; 401/150; 401/270; 604/207 |
Current CPC
Class: |
A61J
7/0053 (20130101); A46B 11/0041 (20130101); A46B
11/0058 (20130101) |
Current International
Class: |
A46B
11/00 (20060101); A61J 7/00 (20060101); A61J
007/00 (); B43K 005/18 (); B67D 003/00 () |
Field of
Search: |
;128/222,260,261,269,62A
;222/92,105,106,187,205,325,326 ;132/84
;401/119,133-135,140,151,156,171,176,178,183,186,198,270,278,150,146 |
References Cited
[Referenced By]
U.S. Patent Documents
Foreign Patent Documents
|
|
|
|
|
|
|
523,340 |
|
Apr 1956 |
|
CA |
|
806,424 |
|
Dec 1936 |
|
FR |
|
Primary Examiner: Gaudet; Richard A.
Assistant Examiner: McGowan; J. C.
Attorney, Agent or Firm: Alexander, Sell, Steldt &
DeLaHunt
Claims
What is claimed is:
1. A device suitable for dispensing medicinal fluids in repeated
measured dosage amounts with predetermined minimum time delay
between consecutive doses comprising:
an applicator head embodying a medicament spreading means;
a handle means attached to said head;
a first reservoir containing a quantity of medicament fluid
constituting a plurality of single doses contained within said
handle means;
a second reservoir for containing and storing a single dose amount
of said fluid medicament within said handle means;
dispensing means adapted to deliver the medicament fluid contained
in said second reservoir to said medicament spreading means; and
time-delayed filling means connecting said first reservoir and said
second reservoir, said means being adapted to positively refill
said second reservoir over a predetermined period of time not less
than about 30 minutes;
whereby after each dose of medicament of predetermined amount has
been delivered to the applicator head for application of said
medicament to a desired area for treatment said device will
dispense a following dose of medicament only after said
predetermined period of time.
2. The device of claim 1 where said time-delayed filling means is a
capillary tube.
3. The device of claim 1 where said time-delayed filling means is a
semi-permeable membrane.
4. The device of claim 1 where said second reservoir has a sponge
contained therein to retain the medicament.
5. The device of claim 1 where said medicament is an aqueous
solution of stannous fluoride.
6. The device of claim 1 where said medicament is an aqueous
solution of sodium fluoride.
7. The device of claim 1 where said medicament is an aqueous
solution of fluoride ion producing compound.
8. The device of claim 1 where said medicament is a solution of
antibiotic.
9. The device of claim 8 where said medicament is a solution of
tetracycline.
10. The device of claim 1 where said medicament is a solution of
antibacterial agent.
11. The device of claim 10 wherein the medicament is a solution of
chlorhexidine.
12. The device of claim 1 having means associated with said second
reservoir to positively empty said reservoir when it is desired to
dispense the medicament.
13. The article of claim 6 where said means connecting said second
reservoir and said first reservoir comprises a permeable
membrane.
14. The article of claim 6 where said second reservoir is refilled
with a single dose of fluid medicament over a period of about 30
minutes to 4 hours.
15. A tooth brush suitable for dispensing repeated dosage amounts
of a fluid medicament on a time-delay basis comprising:
a brush head having attached thereto a plurality of bristles
suitable for cleaning teeth;
a handle attached to said head;
a first reservoir containing multiple dose amounts of fluid
medicament contained within said handle;
a second reservoir for containing a single dose amount of said
medicament within said handle and containing a spongelike
fluid-holding material; a fluid duct connecting said second
reservoir with said brush head; a time-delayed filling means
connecting said first reservoir and said second reservoir adapted
to fill said second reservoir over a predetermined period of time
not less than about 30 minutes; and
means adapted to compress said fluid-holding material in said
second reservoir thereby delivering a single dose of medicament to
said brush and allowing the application of a following dose of
medicament only after said predetermined period of time.
16. The tooth brush of claim 15 where said medicament is one which
is normally unstable when mixed with toothpaste.
17. The article of claim 15 where said medicament is a solution of
sodium fluoride.
18. The article of claim 15 where said medicament is a solution of
stannous fluoride.
19. The article of claim 15 where said medicament is a solution of
fluoride ion producing compound.
20. The article of claim 15 where said medicament is a solution of
tetracycline.
21. The article of claim 15 where said medicament is a solution of
chlorhexidine.
Description
BACKGROUND OF THE INVENTION
1. Field of the Invention
In one aspect this invention relates to tooth brushing. In another
aspect this invention relates to dispensing brushes suitable for
dispensing medicinal fluids.
2. Prior Art
Fountain or dispensing tooth brushes are known in the art; examples
are disclosed in U.S. Pat. Nos. 1,168,965 issued to Rosenblum;
1,676,601 issued to Cavanaugh; 2,814,816 issued to Pepping et al.;
2,987,743 issued to Capps; and 3,256,894 issued to Sherman. These
tooth brushes disclose various mechanisms for storing and
dispensing quantities of a fluid or semi-solid material to the
bristles of a tooth brush.
Many materials are known to be of value in the prevention and/or
treatment of oral disease. Examples include fluorides such as
sodium fluoride, antibiotics, e.g. tetracycline, and bactericides,
e.g. chlorhexidine. In general, these materials share the problem
of toxicity when administered in large doses. Therefore, the dosage
of these materials applied by a dispensing brush containing such
materials is important and must be regulated. Prior art brushes do
not provide means for applying a measured dose and preventing
multiple doses which might prove harmful.
BRIEF SUMMARY OF THE INVENTION
Briefly, the applicator of this invention overcomes the problems
inherent in the prior art. The applicator formed is suitable for
dispensing repeated dosage amounts but on a time-delayed basis so
that an overdose of the medicament is prevented and a therapeutic
dose assured. The applicator of this invention comprises generally
an applicating head having attached thereto suitable medicament
spreading means and a handle means attached to the applicating
head. A primary reservoir containing a quantity of medicament fluid
to be dispensed, said quantity constituting a plurality of single
doses, is contained within the handle attached to the head and a
single dosage reservoir is contained within said head. The dosage
reservoir is emptied by gravity or alternately has a dispensing
means which positively delivers the contents of the dosage
reservoir to the spreading means. A time-delayed filling means
connects the primary reservoir to the dosage reservoir, the filling
means being adapted to positively fill the dosage reservoir over a
predetermined time, but in not less than about 30 minutes. There
may be activating means mounted on the handle to positively empty
the dosage reservoir on the spreading means. When the activating
means are used, a single dose of medicament, in a predetermined
amount is delivered to the spreading means. Following delivery of
the medicament to the spreading means, a second dose cannot be
dispensed immediately, thereby insuring against an overdose. After
the passage of a period of time, generally at least 30 minutes, the
dosage reservoir will be refilled and a repeat application is
possible.
BRIEF DESCRIPTION OF THE DRAWING
A further understanding can be had by referring to the accompanying
drawing in which:
FIG. 1 is a top view of one embodiment of the dispensing tooth
brush of this invention;
FIG. 2 is a cross-sectional view taken along the line 2--2 of FIG.
1; and
FIG. 3 is an exploded perspective view of the brush of FIG. 1.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
Referring to the accompanying drawing in which like reference
numerals refer to like parts in the several views, a tooth brush 10
has a handle 12 and brush head 14. The handle 12 has a collapsible
storage reservoir 16 disposed therein communicating with a dosage
reservoir 18 which has a duct 20 connecting the dosage reservoir
with bristles 22.
In greater detail, as shown the handle 12 and brush head 14 can be
formed of one piece of solid material such as injection molded
plastic. The collapsible storage reservoir 16 is mounted within a
hollow portion of handle 12 and has an aperture 24 which is closed
by a semi-permeable membrane 26. The membrane is held in place over
aperture 24 by a coupling 28. The coupling also serves, in
conjunction with shaped portion 30 of the brush handle 14, to hold
the collapsible primary reservoir 16 in fluid communication with
the dosage reservoir 18. The semi-permeable membrane 26 insures
that the release of medicinal fluid into dosage reservoir 18 will
take place over a substantial period of time and that multiple
doses of medicament are not fed into and out of the dosage
reservoir over a short period of time. The dosage reservoir 18
contains a sponge 32 which is capable of absorbing and holding a
single dose of medicament within the dosage reservoir 18. The
sponge insures that the entire dose of medicament will be held
within the dosage reservoir until activation of the brush so that a
full dose is delivered upon activation, also, after filling of the
dosage reservoir 18 the medicament will not continuously drain
through duct 20 onto the bristles.
When it is desired to dispense a dose of medicament, a plunger
assembly comprising plunger 34, spring 36 and O-ring 38 is pushed
downward, the bottom surface of plunger 34 squeezing sponge 38 to a
compressed state and releasing the medicament imbibed therein into
duct 20. The imbibed medicament flows through duct 20 and onto the
bristles 22 of brush 14. After activation spring 36 returns the
plunger 34 to the upper open position allowing sponge 32 to expand
to its uncompressed state and imbibe additional medicament as it
permeates through the semi-permeable membrane 26.
The applicator of this invention is useful, e.g. for safely
dispensing measured amounts of medicinal agents into the buccal
cavity for the prevention or treatment of oral disease. An
effective medicament is a solution of sodium fluoride of about 5
percent concentration by weight. It is also useful in dispensing
other medicaments operational in the buccal cavity including
soluble inorganic fluorides, antibiotics such as tetracycline, and
bactericides such as chlorhexidine. The time delay metered dosage
form brush may also be used for application of medicaments to
external portions of a body where one wants the combination of
medicament delivery and cleansing action achievable with a brush
sponge or the like.
The handle and applicating head of this invention can be made as a
unit such as shown in FIG. 1 or may be made separately and only a
portion of the device replaced when necessary. Suitable materials
for forming the handle and applicating head are low creep plastics
e.g. cellulose propionate. The materials can be selected on the
basis of cost, ease of manufacture, nonreactivity with the
medicament to be dispensed as well as other processing
variables.
The spreading means can comprise bristles such as those commonly
used in tooth brushes, sponges, fiberous or non-woven pads and
similar porous applicating and spreading means well known in the
art.
* * * * *