U.S. patent number 3,889,681 [Application Number 05/519,245] was granted by the patent office on 1975-06-17 for cryosurgical spraying apparatus.
Invention is credited to Bobby Lee Limmer, Felix M. Sandlin, Jack Douglas Waller.
United States Patent |
3,889,681 |
Waller , et al. |
June 17, 1975 |
Cryosurgical spraying apparatus
Abstract
An insulated, compact, mobile cryosurgical instrument is
provided that has no moving parts in contact with a liquefied gas
coolant retained in an insulated container. Upon interrupting
normal venting from the container, the liquefied gas coolant will
build up a pressure in the container which pressure can be
increased by a squeeze pressure device. The pressure will cause the
liquefied gas coolant to spray from a nozzle until normal venting
is restored.
Inventors: |
Waller; Jack Douglas (Sunray,
TX), Limmer; Bobby Lee (San Antonio, TX), Sandlin; Felix
M. (San Antonio, TX) |
Family
ID: |
24067472 |
Appl.
No.: |
05/519,245 |
Filed: |
October 30, 1974 |
Current U.S.
Class: |
606/22 |
Current CPC
Class: |
A61B
18/0218 (20130101); A61B 2017/00774 (20130101) |
Current International
Class: |
A61B
18/00 (20060101); A61B 18/02 (20060101); A61B
17/00 (20060101); A61B 017/36 () |
Field of
Search: |
;128/303.1,173R,400
;62/293 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Trapp; Lawrence W.
Attorney, Agent or Firm: Lee; Ted D. Comuzzi; Donald R.
Claims
We claim:
1. A cryosurgical instrument for treating skin lesions
comprising:
an insulated container for holding a liquefied gas coolant;
cap means for said insulated container;
a combination vent/pressure line communicating with the inside of
said insulated container;
tubing means extending from near the bottom of said insulated
container to the outside thereof;
nozzle means attached to said tubing means for spraying said
liquefied gas coolant upon pressurization from said vent/pressure
line;
said vent/pressure line being connected to atmosphere through a
first opening and to a source of pressurized air through a second
opening, said first opening being covered before pressurization
through said second opening.
2. The cryosurgical instrument as recited in claim 1 further
comprises a manual squeeze bulb for said pressurization through
said second opening.
3. The cryosurgical instrument as recited in claim 2 wherein said
first opening is adapted for covering by the thumb of the operator
of said squeeze bulb to stop venting before pressurization, and to
instantaneously remove pressurization upon uncovering said first
opening.
4. The cryosurgical instrument as recited in claim 3 wherein said
vent/pressure line and said tubing means extends through said cap
means in an airtight manner.
5. The cryosurgical instrument as recited in claim 4 wherein said
insulated container is a vacuum bottle and said cap means is a cap
for said vacuum bottle.
6. The cryosurgical instrument as recited in claim 1 wherein said
nozzle means is interchangeable.
Description
BACKGROUND OF THE INVENTION
The present invention relates to a cryosurgical instrument and,
more particularly, to a liquid nitrogen spray apparatus that can be
used in treating lesions, benign or malignant, that respond to
cryosurgery.
In the medical practice there have been various types of spraying
apparatus used in cryosurgery for the treatment of skin lesions.
Using layman's terms the skin lesions may be any type of definite
growth in the skin (warts being an example) or an infection in the
skin (acne being an example). In recent years cryosurgery has been
used to treat cancerous or malignant tumors in the skin. The
cancerous areas may be located on either the internal areas of the
body or on the exterior skin.
Regardless of the type of cryosurgical instrument that is used, the
lesion must be frozen to at least minus twenty degrees centigrade
to insure the destruction of all the abnormal cells. Though various
types of liquefied gas coolants may be used in cryosurgical
instruments, the usual liquefied gas used by the medical profession
is liquid nitrogen which has a boiling point of minus 196.degree.C.
Because of the extremely low boiling temperature of liquid
nitrogen, it must be stored in special containers to prevent
evaporation to the atmosphere. Also, if any moving parts come into
contact with the liquid nitrogen they may freeze up or stick due to
a moisture collection from the atmosphere. Any flexible hosing that
may come in contact with the liquid nitrogen becomes very rigid and
brittle.
A cryosurgical instrument in common use today by the medical
profession is shown in U.S. Pat. No. 3,739,956 issued to Reynolds,
a copy of which is submitted with this patent application. In
Reynolds various types of valving apparatus and moving parts are
shown as coming in contact with the liquid refrigerant. All of
these valving apparatus may freeze up in a very short period of
time. Liquid coolant would be evaporated to atmosphere in a very
short period of time. As can be seen from Reynolds, it is a fairly
complex apparatus that would be expensive to manufacture.
Another apparatus commonly used by the medical profession is the
apparatus as shown in the Bryne patent, U.S. Pat. No. 3,534,739, a
copy of which is submitted with the present patent application.
Though Bryne has the advantage of having no moving parts in contact
with the liquefied gas coolant, the coolant is continuously boiling
inside of the container and will completely evaporate in a very
short period of time. By stopping of the normal venting from the
container the pressure is built up to cause a stream of coolant to
be ejected from the nozzle. In a single operation that may require
thirty minutes to perform, the apparatus, as shown in Bryne, would
have to be filled repeatedly. Many operations require the repeated
treatment by the liquid gas coolant over short time intervals to
insure a complete destruction of the lesion. Though the Bryne
apparatus is inexpensive to manufacture it is extremely wasteful of
the liquid coolant as well as being impossible to use for repeated
time interval treatments without refilling with coolant. A later
version of the same apparatus is shown in U.S. Pat. No. 3,651,813,
a copy of which is also enclosed with the patent application.
Various other types of cryosurgical instruments are shown in the
following patents:
______________________________________ INVENTOR U.S. PAT. NO.
______________________________________ Langue 3,537,458 Zacarian
3,702,114 Basiulis 3,736,937 Posch 2,645,097 Nelson 1,659,663
Reynolds 2,258,863 ______________________________________
Though the applicant will not discuss in detail the above
referenced patents, copies are included with the present patent
application for the convenience of the examiner. Previous
discussions of the prior art apply to the referenced patents.
Another apparatus that is being sold in the market today is the
TT-32 Liquid Nitrogen Sprayer by Physicians Products Inc., Box 44,
Millbrae, Calif. 94030. Copies of the sales literature is included
for the convenience of the examiner. Since the liquid coolant is
contained in a vacuum bottle, considerable waste of the liquid
coolant is avoided. The pressure built up inside the vacuum bottle
would not normally be enough to cause a continuous ejection of the
liquid coolant from the nozzle. The valving mechanism immediately
above the squeeze bulb is inconvenient to operate. One hand must be
used to squeeze the bulb and the thumb and forefinger of the same
hand or the other hand being used to operate the valve. The hand
not being used on the bulb and valve, or a second person, must hold
the spray nozzle on the skin lesion and hold the vacuum bottle.
After squeezing the squeeze bulb with the valve closed liquid
nitrogen is ejected from the nozzle; however, liquid nitrogen will
continue to eject from the nozzle until pressure inside the vacuum
bottle has been dissipated. This may result in an excess of the
liquid coolant reaching the skin lesion or adjacent normal areas
with resultant damage to skin tissue. Because the valve is a screw
type valve it is not easy to rapidly open and close resulting in a
loss of the delicate control of the amount of coolant delivered
which is so highly desirable in such a unit especially in treating
very sensitive areas about the eyes, face, genitalia, etc.
In the present apparatus a continuously open vent is provided
immediately above the squeeze bulb that may be closed by placing
the thumb over the opening. Immediately upon removing the thumb
from the opening, the pressure inside the vacuum bottle immediately
decreases to stop the ejection of the liquid coolant. This venting
mechanism provides an extremely delicate and precise control of the
amount of coolant delivered.
In the TT-32 Liquid Nitrogen Sprayer a safety vent valve is
provided immediately above the vacuum bottle stopper. This valve,
which allows for the venting to the atmosphere of any excessive
pressures has the potential problem of freezing up due to moisture
from the atmosphere. Should this valve freeze up, excess pressures
could build up within the unit if the valve above the squeeze bulb
is closed. Once the vent valve freezes the apparatus must be taken
apart to allow the vent valve to thaw before the TT-32 Sprayer can
be used again. The present invention with its continuous open,
simple, thumb controlled venting completely eliminates any
possibility of excess pressure building up within the unit. Also,
the flexible hose from the vent valve to the spray nozzle of the
TT-32 Sprayer is impractical. Once liquid nitrogen flows through
the flexible hose it becomes very rigid and brittle. This hose may
break even under hospital conditions due to the extremely brittle
conditions caused by the low temperature. Although the TT-32 is
inexpensive and does not waste the liquid nitrogen as long as the
vent valve remains open, its use under hospital conditions is very
awkward and inconvenient. The present invention eliminates the
problem of the freezing of the vent valve, the breaking of the
flexible hose through which the liquid nitrogen flows and the
inconvenient operation of the squeeze bulb valve. The present
apparatus prevents an excess of liquid nitrogen from being applied
to the skin lesion because of the extremely precise and delicate
control made possible by the thumb controlled venting. The present
invention also incorporates a standard Leur lock head for the rapid
and easy attachment of tips (needles) of any diameter and length
necessary to treat lesions of any size and location.
SUMMARY OF THE INVENTION
It is an object of the present invention to provide a cryosurgical
instrument for treating skin lesions, benign or malignant.
It is another object of the present invention to provide an
insulated, compact, mobile cryosurgical instrument that is very
easy to use and inexpensive to manufacture.
It is a further object of the present invention to provide a
cryosurgical instrument that minimizes waste of the liquid coolant,
such as nitrogen.
It is yet a further object of the present invention to provide a
cryosurgical instrument with no moving parts that contact the
liquid nitrogen and, simultaneously, be very economical to
manufacture and easy to use in a hospital or office.
It is yet another object of the present invention to provide an
insulated, compact, mobile cryosurgical instrument wherein pressure
can be applied to the liquefied gas coolant and released
immediately by movement of one hand while the other hand maintains
the nozzle on the skin lesion being treated .
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a perspective view of the cryosurgical spraying
apparatus.
FIG. 2 is an elevated cross sectional view of the cryosurgical
spraying apparatus.
DESCRIPTION OF THE PREFERRED EMBODIMENT
Referring now to FIGS. 1 and 2 in combination, the cryosurgical
spraying apparatus is represented generally by the reference
numeral 10. The cryosurgical spraying apparatus 10 has an insulated
container 12 that is similar to a common vacuum bottle. The
insulated container 12 has an inner wall 14 and outer wall 16 with
a space 18 contained therebetween. The space 18 also extends
between the bottom 20 of inner wall 14 and bottom 22 of outer wall
16. The upper portion of the insulated container 12 consists of a
cap 24 threadably connected to the upper portion of outer wall 16
with a sealing ring 26 providing a good seal therebetween. The
upper portion of the insulated container 12 contains an opening 28
through which a liquefied gas coolant may be inserted upon removing
the cap 24.
The cap has holes 30 and 32 contained therein. Through hole 32
extends tubing 34 to nearly the bottom 20 of inner wall 14. The
tubing 34 should be of a suitable noncorrosive metal substance for
receiving a liquefied gas coolant contained inside of the insulated
container 12. The upper portion of the tubing 34 which extends
through hole 30 has a ninety degree bend 36 to the left.
Immediately below the 90.degree. bend 36 are thread connections 38
of tubing 34 to which a suitable retaining nut 40 may be attached.
The retaining nut 40 securely locates the tubing 34 and the ninety
degree bend 36 to the cap 24. To provide a good seal with the cap a
resilient washer could be used; however, because of the extremely
low temperature of liquid nitrogen and the brittle nature of a
resilient washer at these temperatures, a clear epoxy type sealant
is used in the preferred embodiment.
The leftmost portion of the ninety degree bend 36 provides a large
nozzle 42 to which needle 44 may be attached. The large nozzle 42
has a Leur type locking head formed by inner tubing 46 and outer
structure 48 for retaining the needle 44. Slots 50 have been
provided in the outer structure 48 to provide ease of installation
of the needle 44 by preventing the trapping of pressurized air
behind the needle 44. The needle 44 has a small tip to provide the
application of the liquefied gas coolant to a very localized area.
Other types of needles or nozzles may be used according to the
particular needs of the individual case.
Through hole 32 of cap 24 is inserted a ninety degree flange
fitting 54. The lowermost portion of the flange fitting 54 is
threadably connected to nut 56. Again a clear epoxy type sealant is
being used to prevent the escape of pressurized gas through holes
32, but it should be understood that other types of seals may be
utilized. A flexible rubber hose 58 is connected to flange fitting
54 for fluid communication with the inside of insulated container
12. The opposite end of the flexible rubber hose 58 is connected to
T-valve 60 with one side of the T-valve having an opening 62 to
atmosphere. The opening 62 terminates in a thumb press flange 64
whereby a thumb of the operator of the cryosurgical spraying
apparatus 10 may cover the opening 62 when the apparatus is being
used. The other side of the T-valve 60 is connected to a squeeze
bulb 66 which may be utilized to pressurize the inside of insulated
container 12 via flange fitting 54, tubing 58 and T-valve 60. The
bottom of squeeze bulb 66 has a one-way Reed valve 68 that allows
air to flow into the squeeze bulb 66 but not vice-versa. The Reed
valve 68 consists of an opening 70 inside of the squeeze tube 68
which is covered with a thin metal strip 72. Upon squeezing the
squeeze bulb 66 the thin metal strip 72 covers the opening 70 to
prevent the escape of air through opening 70.
In the present invention needle 44 is shown with a small tip 52;
however, other types of needles or nozzles may be used including a
nozzle that would spray a large area for treatment of skin
conditions such as acne. Particular types of spraying attachments
may be desirable when treating a cancerous growth, or other skin
lesions. Many other types of needles may be utilized depending upon
the particular situation.
METHOD OF OPERATION
The cap 24 is unscrewed from the insulated container 12. The liquid
nitrogen is then poured through the opening 28 into the insulated
container 12 and the cap 24 is placed back on the insulated
container 12. The cap 24 should be tightened until the seal ring 26
provides a good seal with the outer wall 16. The liquefied gas
coolant inside of insulated container 12 (usually liquid nitrogen)
would need a vent to atmosphere to keep excessive pressures from
building up because of the extremely low temperature. In the
cryosurgical spraying apparatus 10 a vent is provided through
flange fitting 54, flexible rubber hose 58, T-valve 60 and out
opening 62. Normally one filling of insulated container 12 will
last an entire working day of 8 hours without refilling.
Whenever the cryosurgical spraying apparatus 10 is needed a person
such as a medical doctor could immediately pick up the apparatus,
put the small tip 52 of needle 44 to the area being treated and
squeeze the squeeze bulb 66 while simultaneously placing his thumb
over opening 62. The squeezing of the squeeze bulb 66 will create a
pressure inside of insulated container 12 thereby forcing the
liquid nitrogen up tubing 32 through 90.degree. bend 36 and out
through the needle 44. As soon as the desired amount of liquid
nitrogen has been applied to the skin lesion, the thumb can be
removed from thumb press flange 64 thereby uncovering opening 62.
This will immediately relieve the pressure inside of insulated
container 12 thereby stopping the flow of the liquid nitrogen out
needle 44. This process can be repeated as many times as
cryosurgical treatment is necessary during an operation. Because
the container is well insulated the liquid nitrogen will last for
an extended period of time for repeated treatments.
In the present apparatus there are no moving parts that will come
in contact with the liquid nitrogen and therefore be subject to
freezing due to moisture condensation. Also pressure inside of the
container can be relieved immediately by simply removing the thumb
from the thumb press flange 64, thereby stopping the flow of liquid
nitrogen thus enabling the treating physician to apply a very
controlled amount to a localized area.
* * * * *