U.S. patent number 3,871,913 [Application Number 05/332,077] was granted by the patent office on 1975-03-18 for cleaning of dialyser compartments and blood lines of artificial kidney machine.
This patent grant is currently assigned to Dialysis Systems Limited. Invention is credited to Stanley Shaldon.
United States Patent |
3,871,913 |
Shaldon |
March 18, 1975 |
CLEANING OF DIALYSER COMPARTMENTS AND BLOOD LINES OF ARTIFICIAL
KIDNEY MACHINE
Abstract
A system for supplying a blood dialyser with dialysing fluid
with connections enabling the system to be connected with the
dialyser blood compartment, so that after a dialysing treatment,
the supply system can be used to supply washing and sterilizing
liquid both to the blood compartment and the dialysate compartment
of the dialyser.
Inventors: |
Shaldon; Stanley (London,
EN) |
Assignee: |
Dialysis Systems Limited
(London, EN)
|
Family
ID: |
9994684 |
Appl.
No.: |
05/332,077 |
Filed: |
February 13, 1973 |
Foreign Application Priority Data
|
|
|
|
|
Mar 14, 1972 [GB] |
|
|
11898/72 |
|
Current U.S.
Class: |
134/22.18;
134/22.11; 134/42; 210/636; 134/26; 210/321.69 |
Current CPC
Class: |
A61M
1/365 (20140204); A61M 1/1684 (20140204); A61M
1/169 (20130101) |
Current International
Class: |
A61M
1/16 (20060101); A61M 1/36 (20060101); B08b
009/02 (); B08b 009/08 () |
Field of
Search: |
;210/321,22
;134/22R,26,42,22C |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Bashore; S. Leon
Assistant Examiner: Tushin; Richard H.
Attorney, Agent or Firm: Cushman, Darby & Cushman
Claims
I claim:
1. A method of washing a blood dialyser of an artificial kidney
machine of the type having a supply system which produces dialysate
by mixing water with metered quantities of dialysate concentrate
and heats and deaerates the resultant mixture, said dialyser having
a blood compartment and a dialysate compartment, said method
comprising the steps of:
a. connecting the blood compartment of said dialyser to said
dialysate supply system of said machine, and
b. using liquid from said supply system to wash both the blood and
dialysate compartments of said dialyser.
2. A method as recited in claim 1 wherein the step of connecting
the blood compartment of said dialyser to said dialysate supply
system is accomplished by connecting ends of a blood circuit, said
ends previously having been attached to a patient's blood supply,
containing said blood compartment and a blood pump to said
dialysate supply system so that said blood pump circulates liquid
from said supply system through said blood circuit.
3. A method as recited in claim 1 wherein the washing liquid for
both said compartments of said dialyser initially comprises
dialysate.
4. A method as recited in claim 3 wherein the method comprises the
additional step of washing both said compartments of said dialyser
with pure heated and deaerated water from said supply system after
said washing with dialysate.
5. A method as recited in claim 1 wherein the method comprises the
additional step of providing a sterilizing medium to said supply
system to supply said sterilizing medium to both said compartments
of said dialyser after said washing of said compartments.
6. A dialysate supply system for an artificial kidney machine with
a dialyser having a blood circuit including blood supply lines and
blood and dialysate compartments, said supply system comprising
means for producing dialysate by mixing water with metered
quantities of dialysate concentrate and heating and deaerating the
mixture, and connection means for connecting said supply system
with said dialyser blood circuit so that after a blood dialysate
treatment liquid from said supply system can be delivered to said
dialyser blood compartment for washing said compartment.
7. A system as claimed in claim 6, including a pair of dialysate
header tanks in liquid-flow communication wherein said connection
means comprise a connection leading into each tank.
8. A system as claimed in claim 7, wherein one of said tanks is an
overflow tank from the other of said tanks.
9. A system as claimed in any of claims 6 including means for
introducing a sterilizing medium into the system and hence into
said blood and dialysate compartments of said dialyser.
Description
This invention relates to artificial kidney machines for blood
dialysis. Such machines comprise a dialyser, which may take a
number of forms such as parallel flow, coil or capillary type of
dialyser, and systems for pumping the blood and dialysing fluid or
dialysate through the dialyser.
After a dialysis treatment has been completed using a machine of
the above type, it is necessary to wash and sterilize the entire
machine system including the dialyser compartments, in preparation
for a subsequent dialysis treatment. It is an object of the present
invention to provide a novel method and means for cleaning and
sterilizing the blood and dialysate compartments of a dialyser
after use.
According to the invention, after a dialysis treatment, we connect
the blood compartment of a dialyser to the dialysate production and
supply system of the machine and utilize the system to supply
liquid to both the blood and dialysate compartments of the dialyser
for washing and/or sterilizing purposes.
According to a further feature of the invention, we provide the
dialysate production and supply system of an artificial kidney
machine with connections enabling the system to be connected with a
blood circuit of a dialyser so that liquid from the supply system
can be delivered to the dialyser blood compartment for washing
and/or sterilizing purposes after completion of a dialysis
treatment.
The invention will now be described by way of an example with
reference to the accompanying drawing which is a circuit diagram of
an artificial kidney machine.
The machine comprises a dialysate production and delivery system A
and a dialyser B which may be of the parallel flow, coil or
capillary type. System A includes a dialysate production
arrangement 1 not shown in detail in the drawing but comprising
conventional mainswater and dialysate mixing and concentration
control means 1 and conventional mixture heating means 1', the
arrangement 1, 1' supplying dialysate to the base of a first header
tank 2 from where the dialysate circulates through a de-aerating
conventional circuit 3 and is pumped into a second header tank 4
linked to the first tank as shown. (Tanks 2 and 4 could be combined
into a single partitioned tank). Tank 4 has an overflow 5 leading
into a third tank 6 on a lower level, tank 6 itself having an
overflow 7 going to drain. A connection 8 from tank 4 leads to the
dialysate compartment or compartments of the dialyser and during a
dialysis treatment, dialysate is constantly drawn through the
dialyser from tank 4 by a pump 9 and discharged to the drain, the
dialysate supply being continuously replenished by the production
system, which is run so that tanks 2, 4 and 6 are all kept flushed
with liquid. Further, during dialysis, the blood compartment or
compartments of the dialyser continuously receive blood from a
patient through a blood circuit comprising an intravascular needle
fitting, a supply line 10 and blood pump 11, the blood being
returned to the patient from the dialysis through a further blood
line 12 and needle fitting. Thus during dialysis, dialysate is
continuously pumped through the dialysate compartment(s) of the
dialyser while a patients blood is continuously circulated by the
blood circuit, through the blood compartment(s) of the
dialyser.
When dialysis has been completed, first the needle through which
blood passes from the patient is removed from the patient and this
end of the blood circuit is connected to a saline supply so that
continued operation of the blood pump 11 returns all the patients
blood from within the dialyser at which stage the blood inlet
needle is removed from the patient. The blood circuit is then
purged of saline after which the opposite ends of the blood circuit
lines 10 and 12 (previously connected to the patients blood supply)
are attached to connections 13 and 14 respectively, leading to and
from tanks 4 and 6. By this means, continued operation of the blood
pump 11 causes dialysate from the supply system A to be circulated
through the blood circuit for washing purposes. By suitable
operation of pumps 9 and 11, both the blood circuit and the
dialysate circuit, including the dialyser compartments can be
flushed with dialysing fluid and subsequently with pure water by
shutting off the supply of dialysate concentrate.
Finally, after the system has been thoroughly flushed with water,
the circuits can be charged with a sterilizing medium, by the
introduction of a sterilizing concentrate such as formalin
concentrate from a supply 15 to the tank 2 by the operation of a
pump 16 and continued operation of pumps 9 and 11 for a time
sufficient fully to circulate the sterilizing mixture.
Alternatively, the sterilizing medium may be introduced by venturi
means and it could be introduced into the line 1 instead of into
the tank 2.
It will be appreciated that the invention provides an in situ
method of washing both the blood and dialysate compartments of the
dialyser utilizing the dialysate supply system of the machine.
Moreover, the invention provides a method of distributing a
concentrated toxic sterilizing solution, such as a formalin
solution, after dilution, to the dialyser without the necessity of
handling the concentrated solution and without the effects of
having toxic vapours from the solution within the system
environment. This is of particular importance for individuals with
sensitive skins.
It will also be appreciated that while the invention has been
described in relation to one particular form of dialysate supply
system, it is also applicable to other forms of supply system.
* * * * *