U.S. patent number 3,841,306 [Application Number 05/300,572] was granted by the patent office on 1974-10-15 for implantable, non-contacting nerve stimulating transducer.
This patent grant is currently assigned to Iowa State University Research Foundation Inc.. Invention is credited to Richard C. Hallgren.
United States Patent |
3,841,306 |
Hallgren |
October 15, 1974 |
IMPLANTABLE, NON-CONTACTING NERVE STIMULATING TRANSDUCER
Abstract
An implantable transducer for stimulating a nerve without
contacting it includes a subcutaneous receiver coil having a low
number of turns, of the order of six, which is implantable in an
accessible location. A magnetic core including first and second
separable sections is placed to form a complete magnetic path
around the nerve desired to be stimulated, and an excitation coil
having about three turns is wound around one section of the core. A
pair of conducting wires connect the excitation coil with the
receiver coil. The nerve is stimulated by placing an external coil
of like dimensions adjacent the receiver coil and pulsing it
electrically.
Inventors: |
Hallgren; Richard C. (Ames,
IA) |
Assignee: |
Iowa State University Research
Foundation Inc. (Ames, IA)
|
Family
ID: |
23159665 |
Appl.
No.: |
05/300,572 |
Filed: |
October 25, 1972 |
Current U.S.
Class: |
600/13 |
Current CPC
Class: |
A61N
1/372 (20130101); A61N 1/40 (20130101) |
Current International
Class: |
A61N
1/372 (20060101); A61N 1/40 (20060101); A61n
001/42 () |
Field of
Search: |
;128/1.3,6.5,2.1,2.5F,419C,419E,419P,419R,421,423,424,404 |
Other References
maass et al., "IEEE Transactions on Magnetics," Vol. MAG-6, No. 2,
June 1970, pp. 322-326. .
Holswade et al., "Journal of Thoracic & Cardiovascular
Surgery," Vol. 44, No. 2, August, 1962, pp. 246-252..
|
Primary Examiner: Kamm; William E.
Attorney, Agent or Firm: Dawson, Tilton, Fallon &
Lungmus
Claims
I claim:
1. Apparatus for external stimulation of a nerve in a body without
contacting the body comprising:
a transducer adapted to be implanted in said body including
low reluctance magnetic means comprising first and second magnetic
members for surrounding a nerve selected to be stimulated and
providing a central lumen through which said nerve passes when said
first and second members are in assembled relation;
an excitation coil including approximately three turns of
conducting wire wound around one of said members;
a receiver coil adapted to be implanted in said body and including
approximately six turns of wire;
conductor means connecting said excitation coil with said receiving
coil and adapted to be located subcutaneously; and
controller means adapted to energize said receiver coil externally
of said body for transmitting electrical pulses to said receiver
coil.
2. The system of claim 1 wherein said external excitation means
includes a transmitter coil having a diameter approximately equal
to the diameter of said receiving coil and is placed next to said
receiving coil; and means for periodically exciting said
transmitter coil with pulsed electrical current.
3. The system of claim 2 wherein said receiver coil has six turns
of conducting wire with an approximate diameter of 2.5 .times.
10.sup.-.sup.2 meters and an inductance equal to approximately 6
.times. 10.sup.-.sup.6 henrys.
4. The system of claim 3 wherein excitation means comprises a
capacitor; means for charging said capacitor; and a switch
connected in series with said transmitter coil whereby when said
switch closes, said capacitor is discharged to provide said pulsed
electrical current.
Description
BACKGROUND AND SUMMARY
The present invention relates to the selective and controlled
stimulating of nerves in animals, including stimulation of the
nerve trunks of human beings.
It is known that an electrical signal passed through a nerve trunk
through direct contact can cause stimulation. A contactless
inductive transducer for nerve stimulation has also been reported,
"Contactless Nerve Stimulation and Signal Detection by Inductive
Transducer", J. A. Maass and M. M. Asa, IEEE Transactions on
Magnetics, Vol. MAG-6, No. 2, June, 1970. Heretofore, however,
these prior systems were not able to operate subcutaneously in a
continuous manner or for an extended period of time without causing
a rise in temperature that is inconsistent with the biological
tissue surrounding the implanted device. Devices have been reported
in which a ferrite core, split into semi-torroidal halves, surround
the nerve trunk being stimulated. To my knowledge, the prior
systems employ wires passing through the skin for electrically
energizing the stimulating ferrite core. This, of course, is
disadvantageous because of the inability to absolutely prevent
sepsis of infection through wires passing through the skin and
because of the unsightliness and adverse psychological reaction to
the exposed wires.
In my invention, I include a semi-torroidal magnetic member which
partially surrounds the nerve desired to be stimulated and has
wound on it three turns of wire to provide an excitation coil. The
magnetic path is closed by means of a laminated keeper member which
is used to complete a low reluctance path about the nerve. A pair
of wires connect the excitation coil with a receiver coil, located
subcutaneously in a known, convenient location so that is may be
accessed externally. The receiver coil has only six turns. A
transmitting coil dimensioned similarly to the subcutaneous
receiving coil includes 20 turns.
When the external transmitting coil is placed in proximity to the
subcutaneous receiving coil and pulsed electrically, the resulting
magnetic field excites the receiving coil and a pulse is
transmitted through the connecting wires to the excitation coil to
excite the nerve.
I have found that the present system matches the impedance of the
magnetic core to that of the nerve trunk and reduces the energy
required to stimulate the nerve. This results in operating
temperatures which are compatible with living tissue, so that
operation can be effected for an extended period of time without
undue temperature rise. Further, the present system provides an
implanted stimulation system which can be energized and controlled
without passing wires through the skin.
Other features and advantages of the present invention will be
apparent to persons skilled in the art from the following detailed
description of a preferred embodiment.
THE DRAWING
FIG. 1 is a diagrammatic showing of the elements of the present
system which are located subcutaneously to excite a nerve trunk;
and
FIG. 2 is an electrical schematic diagram showing the primary
elements of the stimulation system.
DETAILED DESCRIPTION
Referring first to FIG. 1, reference numeral 10 generally
designates means for providing a low reluctance path surrounding
the nerve trunk 11. The means 10 includes a semi-torroidal,
C-shaped core 12 defining a central lumen 13 in which the nerve 11
is placed. The C-shaped core may be formed by wrapping silicon
steel tape around a suitable form. Any suitable material having a
high saturation flux density may be used alternatively; and the
word "magnetic" as used herein refers to such material.
The means 10 also includes a generally rectilinear keeper member 14
which completes the low reluctance path and comprises a set of
laminated plates engaging the open surfaces of the C-shaped
core.
Both the C-shaped core and liminated keeper member 14 are
surgically implanted, so they are preferably enclosed in any known
suitable non-antigenic material, such as are well-known in the
implantation of various devices and organs within the body, as
indicated by the dashed lines 15 and 16.
An excitation or stimulation coil generally designated by reference
numeral 17 and preferably comprising three turns of enameled copper
wire is wound around the C-shaped core 12, and these wires are
twisted as at 18 to prevent stray pick-up and routed to a suitable,
possibly more easily accessed location directly beneath the skin
where they are wound into a receiver coil generally designated by
reference numeral 20. The receiver coil 20 as well as the
connecting wires 18 are also ensheathed in a suitable non-antigenic
material. The receiver coil 20 preferably comprises six turns of
wire formed to a diameter of approximately 2.54 .times.
10.sup.-.sup.2 meters in diameter with an inductance of 6 .times.
10.sup.-.sup.6 henrys.
Turning now to FIG. 2, the excitation coil 17 wound on the C-shaped
core 12 is schematically shown at 17a, the wires 18a, and the
receiver coil 20 at 20a.
The receiver coil 20a forms the secondary coil of a transformer
generally designated by reference numeral 25 and including a
primary coil 26. Everything to the left of the dashed line 32 in
FIG. 2 is located external to the body, and everything to the right
of that line is surgically implanted in the body, as already
mentioned.
The coil 26 is a transmitter coil, and it preferably is a 20- turn
coil 2.54 .times. 10.sup.-.sup.2 meters in diameter with an
inductance equal to 28.6 .times. 10.sup.-.sup.6 henrys. It has the
same diameter as the receiver coil 20a so that when the two are
superimposed, the mutual magnetic coupling will be enhanced.
A switch 27 is connected in series with a capacitor 28 and the
transmitting coil 26. A dc power source 29 is connected by means of
a switch 31 to charge the capacitor 28. The switches 27 and 31 may
be silicon controlled rectifiers and they are controlled, in turn,
by circuitry (called a "controller" and represented by block 30)
which coordinates the charging and discharging of the capacitor 28
so that the coil 26 is periodically pulsed by the charged capacitor
28 when the switch 27 closes.
The circuitry for charging the capacitor 28 and for controlling the
closing of the switch 27 while preventing shorting of the power
source is disclosed in my co-pending application Ser. No. 300,571
entitled "External Inductive Neural Stimulator System", filed
concurrently; and the subject matter of that application is
incorporated by reference herein for the purpose of enabling the
practice of the present invention briefly, the charging and
discharging of capacitor 28 occur at mutually exclusive times to
avoid shorting the source 29 through the coil 26.
Using the present invention, the sciatic nerve of a dog has been
successfully stimulated with a non-contacting nerve stimulator
operating at temperatures compatible with living tissue. The
capacitor 28 had a capacitance of 500 .times. 10.sup.-.sup.6
farads, and the transmitting coil 26 and receiving coil 20a are as
has already been described.
In operation, when the switch 27 closes, the capacitor 28
discharges through the transmitting coil 26. The transmitting coil
is located next to the receiving coil 20a, which is located
subcutaneously; and because of the mutual inductance existing
between them, a voltage is generated at the terminals of the
receiving coil 20a. The voltage is transmitted by means of the
connecting wires 18a to the stimulation coil 17a on the C-shaped
core member 12. A low reluctance path about the nerve 11 is
provided by the keeper member 14 which may be physically bonded to
the C-shaped core 12 with any suitable adhesive.
The resulting voltage at the terminals of the stimulation coil 17
(or 17a in FIG. 2) generated an electric field which produces a
current sufficient to stimulate the nerve trunk passing through the
lumen 13 of the low magnetic reluctance means 10. Sixty volts on
the capacitor 28 has been adequate to produce visual contractions
of the muscles of the rear leg of a dog.
Thus, by means of the present invention, I have been able to
stimulate nervous tissue with an induced electric field produced by
a non-contacting transducer. A receiving coil, stimulating coil and
low reluctance magnetic path means surrounding the nerve desired to
be stimulated are all implanted wholly beneath the skin, and the
receiving coil is energized externally. Thus, there is no need for
wires to pass through the skin; and with my design, I have found
that operation of the unit does not produce excess temperatures,
considering the environment in which the unit is placed.
Having thus described in detail a preferred embodiment of the
invention, persons skilled in the art will be able to modify
certain of the structure which has been illustrated and to
substitute equivalent elements for those disclosed while continuing
to practice the principle of the invention; and it is, therefore,
intended that all such modifications and substitutions be covered
as they are embraced within the spirit and scope of the appended
claims.
* * * * *