U.S. patent number 3,831,813 [Application Number 05/359,243] was granted by the patent office on 1974-08-27 for high-flow capacity, self-regulating bypass spike.
This patent grant is currently assigned to Haemonetics Corporation. Invention is credited to Allen Latham, Jr..
United States Patent |
3,831,813 |
Latham, Jr. |
August 27, 1974 |
HIGH-FLOW CAPACITY, SELF-REGULATING BYPASS SPIKE
Abstract
A bypass spike suitable for aseptic insertion through a
one-holed stopper into a liquid reservoir for withdrawing liquid at
a rapid rate therefrom. The bypass spike is particularly suitable
for use in a series of liquid reservoirs from which liquids are to
be withdrawn sequentially and in which the vent air of the first of
the reservoirs is used as vent air for all the remaining
reservoirs.
Inventors: |
Latham, Jr.; Allen (Jamaica
Plain, MA) |
Assignee: |
Haemonetics Corporation
(Natick, MA)
|
Family
ID: |
23412969 |
Appl.
No.: |
05/359,243 |
Filed: |
May 11, 1973 |
Current U.S.
Class: |
222/81; 604/405;
604/80; 604/414 |
Current CPC
Class: |
B67D
3/00 (20130101); B67D 7/0238 (20130101); A61M
5/162 (20130101); A61M 2005/1623 (20130101) |
Current International
Class: |
A61M
5/162 (20060101); A61M 5/14 (20060101); B67D
5/01 (20060101); B67D 5/02 (20060101); B67D
3/00 (20060101); B67b 007/26 () |
Field of
Search: |
;222/80,81,89,90,82,88,181,188,193,332,397,4 ;128/214R,227 |
References Cited
[Referenced By]
U.S. Patent Documents
Foreign Patent Documents
Primary Examiner: Reeves; Robert B.
Assistant Examiner: Marmor; Charles A.
Attorney, Agent or Firm: Lepper; Bessie A.
Claims
I claim:
1. A molded plastic bypass spike for effecting liquid flow from a
reservoir, adapted for insertion by its tip end through a one-holed
aseptic reservoir closure and to be sealed therein and having a
spike pin member including a gas vent passage defining means and a
liquid discharge passage, the improvement comprising a spike body
member having a side arm and a discharge connector, a socket member
within said spike body member in which said gas vent passage
defining means terminates and a free passage through said socket
member connecting said side arm with said gas vent passage defining
means and with said discharge connector, said bypass spike being
further characterized in that said gas vent passage defining means
is formed as a thin-walled rigid metal tube centrally positioned
within said spike and extending beyond the molded plastic tip end,
whereby the cross section of said liquid discharge passage is of a
dimension to permit a full, rapid, continuous liquid flow
therethrough.
2. A bypass spike in accordance with claim 1 further characterized
in that said liquid discharge passage is of a height to provide a
hydrostatic head which in combination with said cross section of
said liquid discharge passage is adapted to provide a liquid flow
rate of at least 300 ml per minute.
3. A bypass spike in accordance with claim 2 wherein said liquid
discharge passage is about three inches in length.
4. A bypass spike in accordance with claim 1 wherein said molded
plastic tip end has an outside diameter no greater than about 0.25
inch.
5. A bypass spike in accordance with claim 1 wherein said rigid
metal tube is stainless steel.
6. A bypass spike in accordance with claim 1 wherein said molded
tip end has an outside diameter no greater than about 0.25 inch,
and said rigid metal tube is a stainless steel tube with an outside
diameter of about 0.075 inch and wall thickness of about 0.009
inch, whereby over 50 percent of the cross sectional area of the
passage defined within said tip end is available for liquid
flow.
7. A bypass spike in accordance with claim 1 further characterized
in that said molded plastic tip end has three uniformly spaced
ports serving as the inlet of said liquid discharge passage and
that said tip end has smooth radii around said ports, whereby, when
said tip end is inserted through the sealing diaphragm of said
reservoir closure, any tendency to abrade particles from said
closure is minimized.
8. A bypass spike in accordance with claim 1 further characterized
in that said molded plastic tip end has uniformly spaced ports
serving as the inlet of said liquid discharge passage and that said
tip end has smooth radii around said ports, whereby when said tip
end is inserted through the sealing disphragm of said reservoir
closure, an air-tight seal is formed against said diaphragm as it
is distended and before it is penetrated.
9. A high-flow capacity, self-regulating bypass spike for effecting
liquid flow from a reservoir and adapted for insertion through a
one-holed aseptic reservoir closure, comprising, in combination
a. a molded plastic tubular spike pin member having a tapered tip
end and a connecting end, said tapered tip end having
uniformly-spaced liquid ports and terminating in a gas vent tube
retaining ring;
b. a thin-walled, rigid gas vent tube extending through said gas
vent tube retaining ring of said spike pin member and projecting
beyond both said tip end and said connecting end of said spike pin
member;
c. a cylindrical socket member adapted at one end to be joined to
said connecting end of said spike pin member and terminating at the
other end in an extended discharge tube, said socket member having
therein an essentially rectangular insert member adapted to provide
a seat for that end of said gas vent tube which projects beyond
said connecting end of said spike pin member and having passage
means providing fluid communication between the passage within said
gas vent tube and the outside of said socket member, said socket
member also defining at least one passage in said insert member for
providing fluid communication between the interior of said tubular
spike pin member and said extended discharge tubing thereby forming
within said spike a connected liquid discharge passage; and
d. a spike body member sealed at one end to said connecting end of
said spike pin member and axially aligned with and surrounding said
socket member and its extended discharge tube, thereby defining an
annular passage around said socket member and said discharge tube,
said spike body member having a side arm and a discharge connector
aligned with said discharge tubing.
10. A bypass spike in accordance with claim 9 wherein said liquid
discharge passage is of a height to provide a hydrostatic head
which in combination with said cross section of said liquid
discharge passage is adapted to provide a liquid flow rate of at
least 300 ml per minute.
11. A bypass spike in accordance with claim 10 wherein said liquid
discharge passage is about 3 inches in length.
12. A bypass spike in accordance with claim 9 wherein said spike
pin member has an outside diameter no greater than about 0.25
inch.
13. A bypass spike in accordance with claim 9 wherein said rigid
gas vent tube is stainless steel.
14. A bypass spike in accordance with claim 9 wherein said spike
pin member has an outside diameter no greater than about 0.25 inch
and said rigid gas vent tube is a stainless steel tube with an
outside diameter of about 0.075 inch and wall thickness of about
0.009 inch, whereby over 50 percent of the cross sectional area of
the passage defined within said spike pin member is available for
liquid flow.
15. A bypass spike in accordance with claim 9 wherein said spike
pin member has smooth radii around said ports, whereby, when said
spike pin member is inserted through the sealing diaphragm of said
reservoir closure, any tendency to abrade particles from said
closure is minimized.
16. A bypass spike in accordance with claim 9 wherein said spike
pin member has three ports and has smooth radii around said ports,
whereby, when said spike pin member is inserted through the sealing
diaphragm of said reservoir closure an airtight seal is formed
against said diaphragm as it is distended and before it is
penetrated.
Description
This invention relates to apparatus for controlling the flow of a
liquid from a series of reservoirs and more particularly to a
bypass spike suitable for aseptic insertion through a single-hole
stopper to achieve a high, automatically controlled flow of liquids
while maintaining the liquids under sterile conditions. The
apparatus of this invention is particularly useful in processing
blood.
Long term storage of human blood requires that it be frozen in a
liquid medium to protect it during storage. U.S. Pat. No. 3,145,913
describes and claims a preferred method and apparatus for handling
blood which is to be stored. The blood is collected directly into a
one-use sterile plastic liner placed in a certrifuge rotor, or in a
disposable rotor without a liner, wherein the red cells are stored
after replacement of the intracellular and intercellular water by
glycerol. When the blood is to be used, it is brought up to
temperature, the liner, if one is used, is placed in a centrifuge
rotor and the glycerol is replaced by a suitable saline liquid
while the red cells remain in the centrifuge.
In the so-called Meryman protocol for deglycerolization, the
deglycerolization comprises treating the blood cells with
prescribed quantities of saline liquids of decreasing
concentrations. As an example, after predilution with a 12% NaCl
solution, the cells are treated with a 1.6% NaCl solution and then
immediately thereafter with an 0.8% NaCl solution. In this
protocol, full quantities of each treating solutions are used in
sequential order. It has been proposed that this treating step
using several different solutions in sequence can be performed
automatically without any intervention by a technician by venting
the first stoppered upturned liquid reservoir, from which the first
treating solution is delivered, into the fluid path of the second
treating solution so that the vent air becomes available to the
second stoppered upturned liquid reservoir only after the first
liquid reservoir is empty. In a similar manner, if a third treating
solution is used, the vent air from the second liquid reservoir is
used in emptying the third liquid reservoir, and so on.
The liquid reservoirs of treating solution are typically rubber
stoppered glass bottles, suspended from a suitable support such as
is shown, for example, in U.S. Pat. No. 3,552,577; and the treating
liquid is gravity fed into a tubing connected to the interior of
the bottle by means of a so-called "bypass spike" which is forced
through a sealing diaphragm in the stopper. The tubing in turn is
connected to a controllable-rate liquid pump such as illustrated,
for example, in U.S. Pat. No. 3,565,286 (FIGS. 10-13). In order to
empty the liquid reservoirs in this manner while maintaining a
completely sterile regime it is necessary to provide a flow of
sterile air into the upturned bottles. It is, of course, possible
to use a two-holed stopper having two separate spikes inserted
through the two holes, one spike for air and one for liquid
discharge. It is preferable, however, from safety and convenience
points of view, to use the commercially available one-holed stopper
and a single spike.
The presently available single-holed stoppers and spikes are made
for the delivery of parenteral solutions at much lower flow rates
than the 300-400ml/minute rate desirable for delivering a treating
solution to a centrifuge rotor in blood declycerolization. The
spikes presently used for delivering parenteral solutions are
molded plastic and their solution and air passages are not
adaptable for handling rapid flow rates. Moreover they rely upon a
plastic tip for puncturing the stopper diaphragm.
It is therefore a primary object of this invention to provide an
improved bypass spike to serve as the means of fluid communication
between the interior of a liquid reservoir and a liquid delivery
tubing. It is another object of this invention to provide a bypass
spike of the character described which provides self-regulating
control of liquid flow at high flow rates. Still another object is
to provide a bypass spike particularly suitable for use in a red
blood cell treating protocol. Other objects of the invention will
in part be obvious and will in part be apparent hereinafter.
The high-flow capacity, self-regulating bypass spike of this
invention is characterized as having a thin-walled stainless steel
tubing inserted in a plastic molded spike to serve as the vent
passage. The stainless steel tubing terminates internally within
the spike in a molded vent passage and socket which are located
around the main liquid passage and it extends externally beyond the
end of the molded plastic tip.
The invention accordingly comprises the features of construction,
combination of elements, and arrangement of parts which will be
exemplified in the construction hereinafter set forth, and the
scope of the invention will be indicated in the claims.
For a fuller understanding of the nature and objects of the
invention, reference should be had to the following detailed
description taken in connection with the accompanying drawings in
which:
FIG. 1 illustrates the use of the bypass spike of this
invention;
FIG. 2 is an exploded view of the bypass spike showing the
alignment and assembly of the four components;
FIG. 3 is a longitudinal cross section of the bypass spike of this
invention;
FIGS. 4 and 5 are two side elevational views of the molded tip end
of the spike;
FIG. 6 is a end-on view of the tip end of the spike pin with the
stainles steel air vent in place;
FIG. 7 is an end-on view of the connecting end of the spike
pin;
FIG. 8 is a cross section of the gas vent socket taken at right
angles to the cross section of this element as shown in FIG. 3;
FIG. 9 is a cross section of the gas vent socket taken through
plane 9--9 of FIG. 3; and
FIG. 10 is a cross section of a one-hole rubber stopper showing the
insertion of the tip of the bypass spike about to puncture the
sealing diaphragm of the stopper.
The use of the high-capacity, rapid-flow bypass spike of this
invention is illustrated in FIG. 1. Liquids which are to be
delivered sequentially are contained within liquid reservoirs 10,
11 and 12 which are held by any suitable means (not shown) to have
their delivery ends facing downwardly so that the liquid may be
gravity fed through liquid delivery conduit 13 to a desired
delivery point, e.g., a centrifuge rotor. A suitable pump (not
shown) may be associated with delivery conduit 13. Each bottle is
closed with a one-holed rubber stopper 14, seen in enlarged cross
section in FIG. 10. It will be seen in FIG. 10 that the stopper has
a sealing diaphragm 15 and a uniquely configured hole 16 so that
when the tip end of the bypass spike punctures the sealing
diaphragm the openings into the spike tip are sealed off until the
spike has completely penetrated through hole 16 and enters the
interior of the bottle. The rubber stopper design and its function
is described to illustrate the use of the bypass spike and it is
not part of this invention.
Returning to FIG. 1, it will be seen that a bypass spike 20 of this
invention is used for bottle 10, spike 21 for bottle 11 and spike
22 for bottle 12. The bypass spike 20 for bottle 10 is connected
through tubing 23 with a source of sterile air (not shown) and
through spike connector tubing 24 to bypass spike 21 for bottle 11;
and bypass spike 21 of bottle 11 is connected through spike
connector tubing 25 with bypass spike 22 of bottle 12. The flow of
fluid from bottle 10 to the centrifuge rotor (not shown), or other
point of delivery, is through bypass spike 20, conduit 24, bypass
spike 21, conduit 25, bypass spike 22 and delivery tubing 13. When
bottle 10 becomes empty as shown in FIG. 1 the air from the bottle
serves as vent air for bottle 11, and so on. By using bottles
containing the precise amount of each liquid required and by
placing them in the correct sequence in which their contents are to
be used, it is possible with the arrangement illustrated in FIG. 1
for the technician to make only one hookup, start the apparatus and
then leave it unattended. The desired sequential delivery of the
liquids is thereafter automatic, and remains fail-safe so long as
no in-between air leak occurs.
FIG. 2 is an exploded view of the high flow rate, self-regulating
bypass spike of this invention, e.g., spike 20 of FIG. 1. The
bypass spike is seen to be formed of four elements: a thin-walled
air vent tubing 30, a spike pin member 31, a socket member 32 with
fluid flow control passages, and a spike body member 33. The spike
pin, socket member and spike body are preferably formed by molding
a suitable synthetic resin material such as a polystyrene,
polycarbonate or the like.
Air vent tubing 30 must be made of a material suitable for forming
a thin-walled (typically 0.009 inch thick) rigid tubing with an
outside diameter of the order of 0.075 inch. It is preferably
formed of stainless steel.
The spike pin member 31 is shown in side elevational view in FIG.
2, in cross section in FIG. 3, in the detailed drawings of the tip
end in FIGS. 4-6 and in the end-on view of the connecting end in
FIG. 7. Reference should be had to all of these drawings wherein
like components are referred to by like reference numerals. The tip
end 35 of spike pin 31 provides three equally spaced openings 36,
37 and 38 defined between three equally spaced connecting members
39, 40 and 41 which join an air vent retaining ring 42 to the main
body 43 of the spike pin (FIGS. 4-6). The tip end preferably has
smooth radii around the three ports 36, 37 and 38, a configuration
which essentially eliminates cutting out any little pieces of
rubber from the stopper when the bypass spike is inserted through
the stopper.
Opposite the tip end 35, the spike pin member has a connecting end
45 adapted for joining to the socket member 32 and body member 33.
This connecting end comprises an outer annular ring 46 joined to
spike pin body 43 through shoulder 47. (FIGS. 3 and 7). Within the
volume 48 defined by outer annular ring 46 is a fitting ring 49
molded integral with shoulder 47 and spike tip body 43.
The internal wall 50 of ring 49 makes a smooth joining with the
internal wall 51 of spike tip body 43. The channel 52 defined
between wall 51 and the air vent tubing 30 terminates at the tip
end at ports 36, 37 and 38 and opens into a liquid channel in
socket member 32 as described below. The external wall 55 of
fitting ring 49 is adapted for joining either by plastic welding or
adhesive bonding techniques to the internal wall 56 of a
socket-defining ring 57 of the socket member 32; and the internal
wall 58 of outer annular ring 46 is similarly adapted for joining
to the external wall 59 of main wall 60 of spike body member 33. In
the particular embodiment of the bypass spike illustrated in FIG.
3, these interfitting walls are so dimensioned that they also make
tight fits between the wall ends and their respective engaging
surfaces so that fluid tight seals are formed. Thus the end surface
61 of ring 49 contacts the internal wall 62 of socket member 32,
the end surface 63 of outer annular ring 46 contacts the surface 64
of seating flange 65 which is integral with wall 60; and the end
surfaces 66 and 67 of socket ring 57 and body wall 60 contact the
internal surface 68 of shoulder 47. This arrangement has been found
convenient for assembling the bypass spike.
The socket member 32 is shown in detail in FIGS. 2, 3, 8 and 9 and
reference should be had to these figures in the following
description wherein like reference numerals are used to identify
like elements. It is the purpose of the socket member and its
associated passage defining elements to provide for the seating and
alignment of the thin-walled air vent tubing, to provide fluid
communication between the air vent tubing and an external
connection and to provide fluid communication for the liquid
flowing through the tip end into a fluid discharge at the end of
the spike. To this end the socket member 32 is formed to comprise a
main socket body 75 and a discharge tubing 76 which extends to
within a short distance of the discharge end of spike body 33. The
socket body 75 is formed as a short cylindrical socket section 77
joined with socket ring 57 which is a part thereof; and socket
section 77 is joined with socket discharge tubing 76 through
shoulder 78. Socket section 77 has oppositely disposed cutouts 79
into which opposite ends of a fluid passage 80, perpendicularly
aligned with gas vent tubing 30, open to annular passage 81 defined
between the external wall of socket tubing 76 and the internal wall
of body member 33. Fluid passage 80 is defined within a socket
insert member 82 which is best seen in FIGS. 8 and 9. This insert
member is essentially rectangular, extending across the diameter of
the socket body 75 and providing a counter-sunk bore 83 in which
gas vent tube 30 is seated. Fluid passage 84 in insert member 82
connects the air passage in vent tube 30 with annular passage 81
which in turn is connected to the passage defined within body side
arm 85 through opening 86. In FIG. 3, connecting arm 85 is
90.degree. out of position for convenience of illustrating it in
cross section. In actual construction, opening 86 faces the wall of
main socket body 75, not cutout 79 as shown.
Since liquid entering through the spike tip must be discharged
through the discharge connector 90 of spike body 33, fluid channel
means must be provided within the socket member to attain this
desired liquid flow. As will be seen from the cross sectional
drawings of FIGS. 3, 8 and 9, this is accomplished by reason of the
essentially flat configuration of socket insert member 82 which
defines oppositely disposed passages 91 and 92 on either side of
the insert member. These passages are open to passage 52 and to the
passage 93 defined within socket discharge tubing 76. This passage
network leading from spike tip end ports 36-38 to spike body
discharge connector 90 is of sufficient height and cross sectional
area throughout to permit the rapid liquid flow rates required.
The relevance of liquid flow path height and the cross sectional
area of the liquid flow path, particularly the diameter of passage
93, may best be understood from a brief analysis of the forces
which produce fluid flow in the system incorporating the bypass
spike. The maximum flow of liquid through the bypass spike from the
liquid reservoir, e.g., bottle 10, to which it is attached is
determined by the height of the liquid surface in the bottle above
the exit of fluid passage 93. Any attempt to increase the liquid
flow rate beyond this maximum value by either creating a vacuum at
the outlet of discharge connector 90 or by supplying air pressure
through connecting arm 85 results in a condition of mixed flow of
air and liquid down through connector 90. Therefore, in a system
such as this, it is not possible to increase the liquid flow rate
through passage 93 beyond the maximum rate set by the hydrostatic
head of liquid above the outlet of passage 93 and by the resistance
to fluid flow that is inherent in the total liquid flow path
extending from ports 36, 37 and 38 in the tip end to the outlet of
passage 93.
Although the one remaining solution, i.e., increasing the length of
discharge tubing 76 (and hence passage 93) and likewise the length
of spike body member 33, would appear to be a simple one, formation
of the components by practical injection molding techniques places
restrictions on the length of such components. Thus, it has been
found that a liquid flow passage length, from ports 36-38 to the
discharge end of tubing 76, of approximately three inches provides
the necessary hydrostatic head to give a liquid flow rate of up to
about 400 ml per minute. This hydrostatic head and flow rate are
maintained right up until the instant the liquid reservoir runs
dry.
The diameter of passage 93 is limited by the density and surface
tension characteristics of the liquid being handled and it should
not be greater than that which will permit the tubing 93
continuously to remain filled with liquid during liquid flow. If
the diameter of passage 93 is larger than the critical size for the
liquid used, bubbles of vent air will enter into it and it will
have only a partial cross section of liquid in it. The presence of
such vent air in passage 93 effects a partial loss in the
hydrostatic head necessary to maintain the high flow rates desired.
In using the bypass spike of this invention to deliver saline
solutions at a flow rate between about 300 and 400 ml per minute,
it has been found that the inside diameter of delivery passage 93
should not be greater than about 0.2 inch using a hydrostatic head
of about 3 inches. This combination of dimensions gives a maximum
flow rate for saline solutions.
The operation of the bypass spike of this invention may be
described with reference to FIGS. 1, 3, 8 and 10. The tip end of
the spike which terminates with the extending exposed end of the
rigid thin-walled gas vent tubing 30 is inserted with pressure
through the sealing diaphragm 15 of the one-holed rubber stopper 14
(FIG. 10) which seals a liquid reservoir, e.g., bottle 10. In like
manner, bypass spikes are inserted into the rubber stoppers of the
bottles containing the remaining liquids to be supplied in
sequence.
Typically, the bottles of saline solutions used in blood cell
processing are under vacuum as received and in order to maintain
aseptic conditions throughout their discharge, it is necessary to
provide sterile vent air and to insure that it remains sterile
throughout the protocol. When the stopper is first penetrated,
there is an in-rush of air, and if this air is derived directly
from the surrounding atmosphere it may carry contaminants. The tip
end of the bypass spike is so designed that when the exposed end of
the air vent tubing 30 just beings to penetrate sealing diaphragm
15 of the stopper (see FIG. 10) the rubber diaphragm stretches over
ports 36-38 effectively sealing them off until the tip end beyond
these ports is sealed. This in turn forces the vent air to enter
through the vent air passage of the bypass spike and makes it
possible to provide sterile air into the bottle. This can be done
by providing already sterilized air or by placing a suitable filter
in the air inlet line 23 (FIG. 1).
In the arrangement illustrated in FIG. 1 the sterile venting air
enters through arm 85 and passes through passage 81, 80 and 84 into
air vent tube 30 which is open to the interior of the bottle.
Liquid from the bottle is discharged through the liquid passage
network, comprising openings 36-38 and passages 52, 91 and 92 and
93, to be discharged through spike discharge 90. So long as liquid
is being discharged from bottle 10 (FIG. 1) the liquid from this
bottle flows through bypass spikes 21 and 22 entering through the
side arm 85 of the spikes and passing directly out through
discharge passage 90 by way of annular passage 81 which must, of
course, have a cross section sufficiently large to permit the
liquid flow rates desired. During this condition of flow no liquid
leaves bottles 11 and 12 because no vent air is available to
them.
Once bottle 10 is emptied, it is used to supply sterile vent air to
bottle 11. At this point, vent air enters side arm 85 of bypass
spike 21 and is delivered to the interior of bottle 11 as described
above. Liquid from bottle 11 then follows the liquid passage
network of passages 52, 91, 92 and 93 for delivery to delivery
tubing 13 through passage 81 of bypass spike 22. Thus any number of
liquid reservoirs may be connected in series for the sequential
discharge of liquids without the need for periodic attendance.
The first bottle of a series, i.e., bottle 10 of FIG. 1 may, if
desired, not use one of the bypass spikes of this invention if
other means are provided to introduce sterile vent air and to
discharge liquid. Thus, for example a two-holed rubber stopper with
an air vent line in one hole and a liquid discharge line may be
used. However, the ability to use the same bypass spike in all of
the series of liquid reservoirs to be discharged sequentially
eliminates any confusion or mix-up.
Commercially available aseptic bottle closures generally
accommodate spikes of about 0.25 inch outside diameter. Using
practical injection molding techniques, the largest internal
diameter of a single-hole spike will have a cross sectional area no
greater than about 65% of the cross sectional area represented by
the outside diameter of the spike. Use of a thin-walled stainless
steel gas vent tube in the center of the internal molded passage
reduces the net cross sectional area available for liquid flow to
about 53 percent. With this net cross sectional area and the
required hydrostatic head as previously defined, the desired flow
rates may be attained. However, if the liquid and gas passages were
both molded, the cross sectional area for liquid flow would be
reduced to far below that required to obtain the desired flow
rates. Thus the combination of a molded liquid flow passage and a
thin-walled metal gas vent passage makes it possible to provide a
bypass spike suitable for use with commercially available aseptic
bottle closures and at the same time capable of achieving
relatively high liquid flow rates.
The use of the thin-walled rigid air vent tubing projecting beyond
the molded tip end and the fluid tip openings possesses the added
advantage of providing means to release air bubbles sufficiently
high within the liquid reservoir to prevent entrainment of the
bubbles in the discharging liquid and likewise to prevent the
impairment of liquid flow control which bubble entrainment would
cause. Moreover, the projecting thin-walled rigid air vent tubing
serves as a very effective tip for easy penetration through the
stopper diaphragm.
It will thus be seen that the objects set forth above, among those
made apparent from the preceding description, are efficiently
attained and, since certain changes may be made in the above
construction without departing from the scope of the invention, it
is intended that all matter contained in the above description or
shown in the accompanying drawings shall be interpreted as
illustrative and not in a limited sense.
* * * * *