U.S. patent number 3,810,367 [Application Number 05/055,512] was granted by the patent office on 1974-05-14 for container for cooling, storage, and shipping of human organ for transplant.
Invention is credited to William D. Peterson.
United States Patent |
3,810,367 |
Peterson |
May 14, 1974 |
CONTAINER FOR COOLING, STORAGE, AND SHIPPING OF HUMAN ORGAN FOR
TRANSPLANT
Abstract
A system of containers having an organ holding container in a
compartment, the compartment having its major interior walls being
a heat transfer cup, the exterior of the heat transfer cup being
another compartment for holding heat absorbing material (ice and
water), the two compartments surrounded by a wall and lids of a
heat insulating material.
Inventors: |
Peterson; William D. (Salt Lake
City, UT) |
Family
ID: |
21998345 |
Appl.
No.: |
05/055,512 |
Filed: |
July 16, 1970 |
Current U.S.
Class: |
435/1.1; 62/371;
62/463; 62/457.1; 435/284.1; 62/64; 62/372; 220/771 |
Current CPC
Class: |
F25D
3/00 (20130101); A01N 1/0273 (20130101); F25D
2331/804 (20130101); A61F 2007/101 (20130101); F25D
2303/081 (20130101) |
Current International
Class: |
F25D
3/00 (20060101); A61F 7/00 (20060101); A61F
7/10 (20060101); F25d 003/08 () |
Field of
Search: |
;62/457,463,371,372,64
;195/104,127,1.7 ;220/94R,94A ;229/43 |
References Cited
[Referenced By]
U.S. Patent Documents
Foreign Patent Documents
|
|
|
|
|
|
|
672,665 |
|
Sep 1929 |
|
FR |
|
402,889 |
|
Dec 1933 |
|
GB |
|
671,497 |
|
Sep 1929 |
|
FR |
|
Primary Examiner: Wye; William J.
Claims
I claim:
1. A method of holding and preserving an animal organ for
sustaining its life and for transporting said organ, having said
organ in a normal saline solution, said solution being kept sterile
within a sealed and removable organ and saline holding compartment,
said sealed compartment having common heat conducting walls to a
heat controlling media containing compartment, said heat
controlling media being a solution of ice and water to control the
temperature of the saline to its temperature by heat transfer to
and from the saline, said heat controlling media containing
compartment having a lid opening for access to service the media,
and said removable organ and saline holding compartment having a
lid opening for access to service the saline and to place in and
remove said organ.
2. Container according to claim 1 with the addition of a sterile
container surrounding the removable organ and saline holding
compartment and interposed between it and the heat controlling
media, said sterile container for keeping the exterior walls of the
removable organ and saline holding compartment sterile.
3. A controlled temperature container comprising of a housing
divided into two compartments separated by a heat-transferring
cup-like member, one of said compartments being adapted to hold an
animal organ and the other of said compartments adapted to hold a
heat absorbing material, said cup being lined with a removable
liner material inert to animal tissue and having an additional
sterile container surrounding the liner and interposed between it
and the cup, having a pair of detachable lids, a first lid on said
housing for opening and closing access to one of said compartments
and a second lid of said housing for opening and closing access to
said other compartment.
4. A controlled temperature container comprising of a housing
divided into two compartments separated by a heat-transferring
cup-like member, one of said compartments being adapted to hold an
animal organ and the other of said compartments adapted to hold a
heat absorbing material, having a pair of detachable lids, a first
lid on said housing for opening and closing access to one of said
compartments and a second lid of said housing for opening and
closing access to said other compartment, said lids having feet on
their exterior enabling the standing of the container on either
end, and in which the feet of at least one of said lids are formed
as a handle for carrying the container.
5. Container according to claim 4 with the addition of threads on
the container base and lids, for holding the lids on and in
place.
6. A controlled temperature container comprising of a housing
divided into two compartments separated by a heat-transferring
cup-like member, one of said compartments being adapted to hold an
animal organ and the other of said compartments adapted to hold a
heat absorbing material, said cup being lined with a removable
liner material inert to animal tissue, having a fluid such as water
between the heat transfer cup and the liner to improve the heat
flow from the organ to the heat absorbing material, having a pair
of detachable lids, a first lid on said housing for opening and
closing access to one of said compartments and a second lid of said
housing for opening and closing access to said other
compartment.
7. A controlled temperature container comprising of two
compartments separated by a heat-transferring member, one of said
compartments being adapted to hold an animal organ and the other of
said compartment adapted to hold a heat absorbing material, said
animal organ holding compartment being lined with a removable liner
material inert to animal tissue, and having an additional sterile
container surrounding the liner and interposed between it and the
heat-transferring member.
Description
BACKGROUND OF THE INVENTION
The present invention relates to a need for being able to transfer
a kidney or other human organ from a human cadaver or donor to the
recipiant which in some cases may be many miles away. If an organ
which has been removed is not to be implanted for several hours, it
is desirable that the organ be cooled and maintained at 32.degree.
F, the transition temperature of ice to water. It is also desirable
that the organ be kept sterile in a consistant "normal" saline
solution which could vary if ice were used in the same container
with the organ. It is desirable that an organ being removed from
the donor, be placed in a sterile container, which in turn is
placed in a sterile compartment; such that, when the organ
container is removed from the compartment at the facility for
implantation, the container is sterile and can be handled in the
operating room without fear of contamination to the room and its
contents.
SUMMARY OF THE INVENTION
The invention is a system of containers, the system having two
sealable lids for two separate compartments, the outside walls of
the system and two lids being made of a heat insulating material,
the walls between the two compartments being made of a heat
transferring material or, consisting of a heat transfer cup, the
two compartments being sealed from each other. One compartment of
the system is for holding a container which in turn holds an organ
in a saline solution for cooling, storage, and/or shipping. The
other compartment of the system is for ice and water for cooling
the organ to 32.degree. F and maintaining it at that temperature
until it is to be removed for implantation.
BRIEF DESCRIPTION OF THE DRAWING
The container system is cylindrical in shape, the lid for the ice
chamber forming the base, and the lid for the organ chamber forming
the top and handle. FIG. 1 is a cross section of the container
system. FIG. II is a schematic representation of the container
system showing a simulated sterile container surrounding the liner
and interposed between it and the heat-transferring member. FIG.
III is a schematic representation of the container system showing a
simulated heat transfer media between the heat transfer cup and the
liner.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
The organ container system consists of basically two compartments.
The upper or organ compartment houses the organ container which is
formed as a liner that has a lid 1 which snaps on a cup 2. The lid
1 and cup 2 are standard plastic molded items made of polypropylene
or another material which is inert to human tissue. The human organ
3 or any other animal tissue being stored is kept submerged in a
"normal" saline solution 4. The cup 2 and lid 1 are kept sterile
within the pre-sterilized organ compartment which is sealed from
the outside atmosphere by an O-ring 5. The organ lid 6 is attached
to the container base 7 by threads 8. The cup 2 and lid 1 may be
kept sterile without sterilization of the organ chamber by sealing
them in a sterile container 19 such as a plastic or film bag before
placing them in the organ compartment.
The ice 9 and water 10 compartment is separated from the organ
compartment by a heat transfer cup 11 made of a heat conducting
material such as aluminum. The container base 7 is molded about,
bonded to, and supports the heat transfer cup 11. The heat transfer
cup 11 has an integral inverted cup 12 such that ice 9 floating on
the water 10 is kept against the heat transfer wall or cup 11
bottom. The ice 9 and water 10 compartment is sealed from the
outside atmosphere by an O-ring 13 and is accessible by removal of
a lid 14 which is held in place by threads 15.
The lids 6 and 14 and base section 7 are made of polyurethane or
another heat insulating material with similar properties. The ice
and water compartment lid 14 has integrally molded feet 16
consisting of a circular ring which provides additional insulation
in that it creates an air pocket between itself and the floor it is
set on. The organ compartment lid 6 has an integrally molded handle
17 for carrying the system and also has feet 18 to support the
system when inverted for access to the ice 9 and water 10 chamber
by removal of lid 14.
To improve heat flow between the organ and the coolent a heat
transfer fluid 20 such as water may be incorporated between the
heat transfer cup 11 and the organ container 2.
* * * * *