U.S. patent number 3,744,722 [Application Number 05/102,327] was granted by the patent office on 1973-07-10 for nebulizer.
This patent grant is currently assigned to Cavitron Corporation. Invention is credited to Henry L. Burns.
United States Patent |
3,744,722 |
Burns |
July 10, 1973 |
NEBULIZER
Abstract
A nebulizer for the generation of an aerosol having three major
components mounted within a housing for containing a liquid and
directing the resultant aerosol. The three components are designed
for ease in assembly and disassembly for cleaning. The gas and
liquid are uniformly mixed prior to depositing the liquid onto and
spreading the liquid over a target surface for the final
atomization.
Inventors: |
Burns; Henry L. (Beaverton,
OR) |
Assignee: |
Cavitron Corporation (Long
Island, NY)
|
Family
ID: |
22289296 |
Appl.
No.: |
05/102,327 |
Filed: |
December 29, 1970 |
Current U.S.
Class: |
239/338;
128/200.18; 261/DIG.65 |
Current CPC
Class: |
A61M
11/06 (20130101); B05B 7/0012 (20130101); Y10S
261/65 (20130101) |
Current International
Class: |
A61M
11/06 (20060101); B05B 7/00 (20060101); B05b
007/24 () |
Field of
Search: |
;239/338,370
;128/194 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Wood, Jr.; M. Henson
Assistant Examiner: Love; John J.
Claims
I claim:
1. A nebulizer for generating an aerosol using pressurized gas,
comprising:
a housing having a reservoir containing material to be nebulized,
said housing having an inlet, and
nebulizing means mounted to said housing in fluid communication
with said inlet and said reservoir and having jet power means for
receiving pressurized gas through said inlet and transmitting a
high-velocity gas jet, having tension means in front of said jet
power means, having mixing means between said jet power means and
said tension means, and having a space between said jet power means
and said mixing means for said material to be drawn into the space
between said jet power means and said mixing means, said tension
means contiguous with said mixing means forming a restrictive
passage therebetween for depositing the mixed gas and material
solely on a first portion of said tension means causing the
deposited mixture to move over the surface of said tension means to
a second portion thereof at which point the tendency to move
further and the surface tension of the mixture cause the mixture to
atomize into aerosol particles of a predetermined size range
minimizing unwanted small and large heavy particles.
2. The nebulizer of claim 1, wherein said mixing means has an
orifice and a single recessed cavity on the exit side of said
orifice enabling said gas and material to flow into said
restrictive passage.
3. The nebulizer of claim 1, wherein said jet power means, said
mixing means, and said tension means are slidably aligned with each
other to facilitate assembly and disassembly as well as accurate
alignment thereof.
4. The nebulizer of claim 1, including pressurized gas supply means
slidably mating with said jet power means and pressing said jet
power means against the inside wall of said inlet forming an air
tight fit between said inlet, said jet power means, and said gas
supply means.
5. A nebulizer for generating an aerosol using pressurized gas,
comprising:
a housing having an outlet for the discharge of the aerosol and an
inlet aperture;
a supply tube coupled to the source of pressurized gas and said
inlet aperture;
a reservoir mounted to said housing for containing the material to
be nebulized; and
an aerosol generating subassembly within said housing
including,
a power jet piece having an inlet section coupled to said supply
tube at the inlet aperture for receiving said pressurized gas and a
primary orifice for the gas to exit therefrom,
a cap piece having a secondary orifice and a recessed cavity on the
exit side of the secondary orifice including a rim-like surface,
said cap piece being mounted on said power jet piece such that a
chamber is formed between said orifices which is connected to the
material to be nebulized, and
a target piece mounted in alignment with said cap piece and having
a target surface with a portion thereof being in close proximity to
the rim-like surface forming a restrictive passage such that the
material to be nebulized is uniformly deposited on said target
surface as it passes through the restrictive passage and is spread
over the target surface prior to separating from the target surface
in the form of an aerosol,
the housing further including a planar surface contiguous to the
inlet aperture and two housing guideways on opposite sides of the
housing,
the power jet piece inlet section including a shoulder for aligning
said power jet piece against the planar surface of the housing,
and
the target piece further including two wing plates for locating
said target piece against the housing guideways.
6. A nebulizer for generating an aerosol using pressurized gas,
comprising:
a housing having a reservoir containing material to be nebulized,
said housing having an inlet, and
nebulizing means mounted to said housing in fluid communication
with said inlet and said reservoir and having jet power means for
receiving pressurized gas through said inlet and transmitting a
high-velocity gas jet, having tension means in front of said jet
power means, and having mixing means between and spaced from said
jet power means and said tension means and having the center point
thereof aligned with the center point of said jet power means and
said tension means, said housing including a planar surface
contiguous to said inlet and two housing guideways on opposite
sides of said housing,
said power jet means including a shoulder for aligning said power
jet means against said planar surface, and
said tension means including two wing plates for locating said
tension means against the housing guideways.
7. A nebulizer for generating an aerosol using pressurized gas,
comprising:
a housing having a reservoir containing material to be nebulized,
said housing having an inlet, and
nebulizing means mounted to said housing in fluid communication
with said inlet and said reservoir and having jet power means for
receiving pressurized gas through said inlet and transmitting a
high-velocity gas jet, having tension means in front of said jet
power means, and having mixing means between and spaced from said
jet power means and said tension means and having the center point
thereof aligned with the center point of said jet power means and
said tension means, said housing having guideways, said mixing
means having guideways, said tension means fitting between said
housing and tension means guideways for proper alignment and to
enhance the rigidity of said nebulizing means.
8. A nebulizer for generating an aerosol using pressurized gas
comprising
a housing having an outlet for the discharge of the aerosol, an
inlet aperture, a planar surface contiguous to said aperture, and
two housing guideways on opposite sides of the housing and removed
from said planar surface,
a supply tube coupled to the source of pressurized gas and said
inlet aperture;
a reservoir mounted to said housing for containing the material to
be nebulized; and
an aerosol generating subassembly within said housing
including,
a power jet piece having an inlet section coupled to said supply
tube at the inlet aperture for receiving said pressurized gas, said
inlet section including a shoulder for aligning said power jet
piece against the planar surface of the housing, and a primary
orifice for the gas to exit therefrom,
a cap piece having, a secondary orifice, a recessed cavity on the
exit side of the secondary orifice including a rim-like surface,
and guideways on the exit side of the secondary orifice, said cap
piece being mounted on said power jet piece such that a chamber is
formed between said orifices which is connected to the material to
be nebulized,
a target piece designed to snugly fit between the housing guideways
and cap piece guideways for proper alignment and to enhance the
rigidity of the aerosol generating subassembly, and having a target
surface with a portion thereof being in close proximity to said
rim-like surface forming a restrictive passage such that the
material to be nebulized is uniformly deposited on said target
surface as it passes through the restrictive passage and is spread
over the target surface prior to separating from the target surface
in the form of an aerosol.
Description
BACKGROUND OF THE INVENTION
This invention relates to a new and improved nebulizer, also called
an atomizer or a vaporizer, used to atomize or generate an aerosol
of a liquid-like medication. The medication is usually administered
by inhalation to a patient affected with some disorder, such as
emphysema or asthma. It may consist of a single liquid, a mixture
of liquids, or solid compounds dissolved in a liquid, all
possibilities of which will hereinafter be called "the liquid."
In the treatment of patients having disorders requiring an aerosol,
it is very important that the size of the aerosol or suspended
particles be within a certain size distribution in order for the
particles to reach their intended destination. Generally the most
useful size distribution should be between 0.5 to 5.0 microns.
Particles larger than 5.0 microns are usually too heavy to ever
reach their intended destination and particles smaller than 0.5
microns are too stable and when inhaled will probably never be
deposited at their intended destination but will be discharged
during exhalation. "Efficiency" of performance of a nebulizer is
generally expressed as the quantity of useful aerosol produced per
unit quantity of gas consumed.
Most prior art nebulizers are constructed such that a gas is
introduced into a chamber in the direction of some type of target
arrangement. Prior to reaching the target arrangement, the gas
passes over or through an aspirating means which includes a
capillary tube, one end of which is submerged in a reservoir of a
liquid. As the liquid is drawn up the tube, usually by the
Bernoulli principle, it is propelled against the target arrangement
to be fractured into aerosol particles. The particle size
distribution will depend upon how the gas and liquid mix and the
location of the target arrangement relative to flow of the
gas-liquid mixture.
The invention of this application operates on the theory that due
to the uniformity of mixing and flow distribution of the gas and
liquid, the latter is uniformly deposited on the target
arrangement. Due to the velocity of the gas-liquid mixture, the
deposited liquid is then spread over the surface of the target.
Since the surface area increases in the direction of movement of
the spreading liquid, the liquid becomes increasingly thinner until
its surface tension forces it to atomize into aerosol particles and
leave the target arrangement.
Therefore, the principal object of this invention is to provide a
nebulizer such that the quality of aerosol produced is generally
uniform within a relatively narrow size range useful for medical
purposes and other applications where a stable aerosol is
desired.
Another object of this invention is to provide a nebulizer that has
a high efficiency in the quantity of aerosol produced.
A still further object of the invention is to provide an efficient
nebulizer having a design which is economical to manufacture but
still very reliable in performance.
Another object of the invention is to provide an efficient
nebulizer having a design in which the critical components are
easily assembled, disassembled, cleaned, inspected, and/or
replaced.
There are three essential and novel elements of this inventive
nebulizer. One component, to be called a power jet piece, includes
a gas inlet passage for connection to a source of pressurized gas
and a primary orifice. Another component, to be called a cap piece,
includes an inlet passage for connection to the liquid medication,
a secondary orifice, and a recessed cavity on the exit side of the
secondary orifice, the cavity having a rim-like surface. The power
jet piece and cap piece are assembled having a loose press fit, so
that the orifices are in alignment with each other and a chamber is
formed between the exit plane of the primary orifice and the
entrance plane of the secondary orifice. The chamber connects with
the liquid inlet passage of the cap piece. As the pressurized gas
passes between the two aligned orifices, there is a simulated
venturi throat effect and a negative pressure develops in the
chamber causing the liquid to be drawn into the chamber. Location
of a secondary orifice downstream from where the gas and liquid
meet insures a more thorough mixing. The third component, to be
called a target piece, is slidably mounted on the exit plane side
of the cap piece and has a target which is aligned with the two
orifices and in close proximity to the rim-like surface of the cap
piece's recessed cavity. A restrictive gap is formed between the
target piece and the rim-like surface, so that the liquid flowing
from the secondary orifice through the recessed cavity is deposited
onto the target surface in a uniform manner. These three essential
elements are held in rigid alignment, when the target piece is
placed in position.
BRIEF DESCRIPTION OF THE DRAWINGS
For a more thorough understanding of the invention, reference may
be made to the following description of an exemplary embodiment,
taken in conjunction with the figures of the accompanying drawings,
in which:
FIG. 1 illustrates an overall view, partially in cross section, of
the nebulizer assembly;
FIG. 2 illustrates the three assembled components of the aerosol
generating subassembly, partially in cross section;
FIG. 3 is a cross-sectional view taken along the line 3--3 of FIG.
1; and
FIG. 4 is a view taken along the line 2--2 of FIG. 1, with the
target piece being disassembled from the cap piece.
DESCRIPTION OF EXEMPLARY EMBODIMENTS
Referring to FIG. 1, the nebulizer is constructed of three major
subassemblies; a housing 1, a reservoir 2, and an aerosol
generating subassembly. The aerosol generating subassembly is
composed of three major components: a power jet piece 3, a cap
piece 4, and a target piece 5. In addition, a dip tube 6, which is
shown as a separate part but need not necessarily be, may be
considered part of the aerosol generating assembly. Also, an inlet
fitting 7 couples the aerosol generating subassembly to a
compressed gas supply tube 8. It is preferable that many of these
components be made, at least in part, of a molded material that is
somewhat resiliently deformable, such as molded plastic. In the
following description and discussion two digit numbers will be used
for details and special features with the first digit identifying
the appropriate singular component being described.
The housing 1 has an outlet opening 11, which is connected to
another type of device such as a face mask, a respirator, a vapor
tent, or an atmospheric control chamber, etc., which is designed to
use the aerosol created by the nebulizer. Adjacent to the outlet
opening 11 there is a splatter baffle 12 which prevents any large
aerosol particles from reaching the outlet 11, causing them to
coalesce on the baffle 12 and eventually fall back into the
reservoir 2 for reuse. The housing 1 is coupled to the reservoir 2
by way of a sealing groove 13 and a skirt section 14. The housing 1
has an inlet aperture 15 in its side wall for accepting the aerosol
generating subassembly and a planar surface 16 for accurate
alignment of the aerosol generating subassembly. In addition, there
are housing guideways 17--17 on opposite sides of the housing which
assist in the alignment and the rigidity of the aerosol generating
subassembly. The housing enclosure 18 must be of sufficient volume
to allow the useful aerosol of the desired size to pass to the
outlet opening 11 without excessive interference from the larger
particles which fall back into the reservoir 2.
The reservoir 2 is a generally symmetrical cylindrically shaped
container having a particularly thin wall collar and bead 21 at its
upper surface that can be snapped into the sealing groove 13 of the
housing 1 to prevent a leakage of gas or liquid and obviate the
need for any type of gasket. Size and shape of the reservoir is
independent of the aerosol generating function. However, for
certain uses it may be convenient for the overall size of the
reservoir to be such as to allow significant graduations 23 to
indicate the level of the liquid in the reservoir. A typical
inhalation therapy treatment may require measurements of as little
as a 3 milliliters or less and less than 0.5 milliliters of a
particular component. The graduations 23 preclude the need to use
another device to measure, such as a graduated syringe.
The power jet piece 3 is a symmetrical, cylindrically shaped
component having three different size sections along its length.
Referring to FIG. 2, the inlet section 31 has an internal tapered
section 32, which mates with the inlet fitting 7, and a thin wall
which is expanded radially against the housing inlet aperture 15
(see FIG. 1) when the tapered inlet fitting 7 is inserted into the
power jet piece 3. This expansion of the inlet section 31 of the
power jet piece 3 against the walls of the housing inlet aperture
15 results in a simple, gasketless, leak tight seal, for the gas to
pass through the housing wall, even though there is a free sliding
fit for assembly and disassembly of the components. The outlet end
of the power jet piece 3 has a reduced diameter stud section 33,
the end face of which contains the outlet orifice 35, hereinafter
the primary orifice. The center section 36 of the power jet piece 3
has an external taper for ease of assembly with the cap piece 4, to
be discussed later. In addition, there is a shoulder 37 which is
formed by the diameter change between the center section 36 and the
stud section 33, and a shoulder 38 formed by the diameter changes
between the center section 36 and the inlet section 31. The latter
shoulder 38 provides a stop for aligning the power jet piece 3 with
the reference to the planar surface 16 of the housing 1. (see FIG.
1).
The cap piece 4 has a thin-walled cylindrical entrance portion 41
designed to expand slightly for a leak tight fit over the external
taper of the center section 36 of the power jet piece 3 and a
blocked shaped exit portion 42. When these two pieces are
assembled, the shoulder 37 of the power jet piece 3 abuts against a
triple chord shaped shoulder 43 (see FIG. 4) within the exit
portion 42, forming a triangular cavity 44 within the cap piece 4.
The exit portion 42 of the cap piece 4 also contains an outlet
orifice 45, hereinafter the secondary orifice, and a small diameter
nipple 46 for attachment to the dip tube 6, the latter being
inserted into the reservoir 2. The opening of the nipple 46
connects with the triangular cavity 44 described above. In
addition, there is a gap 47 between the external end face of the
power jet piece 3 and the internal end face of the cap piece 4
which together with the triangular cavity 44 form a chamber. This
chamber connects with the reservoir via the nipple 46 and dip tube
6. The secondary orifice 45 is centrally located and in alignment
with the primary orifice 35. Preferably, the diameter of the
secondary orifice 45 should be slightly larger than the diameter of
the primary orifice 35. The end face of the exit portion 42 of the
cap piece 4 contains two cap piece guideways 48--48 (see FIG. 3),
which are parallel to the housing guideways 17--17, and which also
assist in the alignment and the rigidity of the aerosol generating
subassembly. The end face of the exit portion 42 of the cap piece 4
also contains a recessed cavity 49 having a rim-like surface
49a.
The target piece 5 consists of a tab-like structure 51 containing
two wing plates 52--52 and a target surface 53. The wing plates
52--52 form an acute angle with each other to enhance the rigidity
of the entire aerosol generating subassembly. When fully assembled,
inner surfaces 54--54 of the wing plates 52--52 are in contact with
the cap piece guideways 48--48 and outer edges 55--55 of the wing
plates 52--52 are in contact with the housing guideways 17--17.
This insures proper alignment and rigidity of the entire aerosol
generating subassembly. The target surface 53, which may take many
different shapes is shown as a sphere for ease of manufacture. When
the target piece 5 is snugly mounted between the two sets of
guideways, as described above, the target surface 53 is contiguous
to the rim-like surface 49a of the cap piece 4 forming a
restrictive passage 56.
In operation, a source of compressed gas is connected to the
nebulizer by the supply tube 8 and with adequate pressure this gas
will exit with a high velocity at the power jet primary orifice 35.
As the gas passes from the primary orifice 35 to the secondary
orifice 45, due to the simulated venturi throat formed
therebetween, a negative pressure will be generated in the gap 47.
The gap 47 is part of a chamber including triangular cavity 44,
which has access to the liquid in the reservoir 2 via the nipple
46, and the dip tube 6. Therefore, the negative pressure in gap 47
has a tendency to draw the liquid into the gap 47. The combined gas
and liquid will then pass through the secondary orifice 45 becoming
thoroughly mixed and emerge into the cavity 49. As the liquid-gas
mixture passes through the restrictive passage 56, the liquid is
uniformly deposited upon the target surface 53. Due to the high
velocity of the gas, the liquid will spread across the spherical
surface and due to the increasing surface area in the direction of
the spreading movement of the liquid, the layer of liquid will
become increasingly thinner. This thin layer of liquid will
eventually separate from the spherical target surface 53 in the
form of an aerosol and will move in the general direction of the
outlet opening 11 of the housing 1. The degree of thin-down of the
liquid on the target surface 53 will be a function of the
velocities of the gas and liquid, the amount of liquid initially
deposited on the surface 53, the surface tension of the particular
liquid being used, and the shape of the target surface 53.
Due to the smallness of the secondary orifice 45 and the existence
of the restrictive passage 56, the entire gas jet is used in mixing
with the liquid and depositing the liquid onto and spreading the
liquid over a large portion of the target surface 53. There is no
loss of efficiency due to any non-utilized gas as in the typical
atomizer or nebulizer where usually aerosol production depends upon
impact fracturing as discussed in the introduction, or is due to
only a small portion of the target being exposed to the flow of the
gas and liquid. Nebulizers constructed as described herein produce
useful aerosol at rates in excess of 70 milligrams of pure water
per liter of jet gas. It should be noted that the addition of
medications of any type to the water can of course alter the
surface tension and will have a pronounced effect on rates of
aerosol generation.
The above-described embodiment of the invention is intended to be
merely exemplary, and those skilled in the art will be able to make
numerous variations and modifications of it without departing from
the spirit and scope of the invention. All such variations and
modifications are intended to be included within the scope of the
invention as defined in the appended claims.
* * * * *