U.S. patent number 3,717,174 [Application Number 05/168,642] was granted by the patent office on 1973-02-20 for perfusion safety valve.
Invention is credited to Richard A. Dewall.
United States Patent |
3,717,174 |
Dewall |
February 20, 1973 |
PERFUSION SAFETY VALVE
Abstract
A perfusion safety valve for use in blood oxygenating systems.
The valve includes an elongated, rigid, perforated tube and
interiorly disposed therein is a collapsible membrane-like wall
which may collapse to cut off the flow of blood through the tube.
Exteriorly of the tube is a second membrane-like wall and the space
between the two membrane walls is filled with a liquid. When a
slight vacuum is pulled against the inner membrane wall, the liquid
will pass through the perforations of the tube into the interior of
the tube to cause collapse of the interior wall to shut off the
flow through the valve to preclude the pumping of air into the
arterial system of a patient using the oxygenating system.
Inventors: |
Dewall; Richard A. (Dayton,
OH) |
Family
ID: |
22612348 |
Appl.
No.: |
05/168,642 |
Filed: |
August 3, 1971 |
Current U.S.
Class: |
137/565.15;
137/844; 251/5; 422/48; 604/34 |
Current CPC
Class: |
A61M
5/36 (20130101); A61M 39/228 (20130101); Y10T
137/86019 (20150401); Y10T 137/788 (20150401); A61M
1/3621 (20130101) |
Current International
Class: |
A61M
39/22 (20060101); A61M 39/00 (20060101); A61M
5/36 (20060101); A61M 1/36 (20060101); A61m
005/16 () |
Field of
Search: |
;23/258.5 ;251/4,5
;128/214R,214E,214F,274 ;137/494,511,525,525.1,565 ;3/DIG.3 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Cohan; Alan
Assistant Examiner: Michalsky; Gerald A.
Claims
I claim:
1. A blood oxygenating system including a perfusion safety valve
comprising an elongated, relatively rigid, perforated tube; means
at each end of said tube for connecting the same into a conduit in
which blood is flowing; a peripheral inner membrane wall formed of
a flexible material compatible with blood within said tube; an
outer membrane wall outside of said tube; said inner and outer
membrane walls defining a closed space; and a liquid within said
closed space; whereby when blood is flowing through said tube, said
inner membrane wall will be in substantial abutment with the
internal surface of said tube while when blood ceases to flow to
said tube, a slight vacuum in the blood line will cause the liquid
in said closed space to flow through the perforations in said tube
to cause said inner membrane wall to collapse upon itself to seal
off the blood line, a blood oxygenator adapted to receive blood
from a patient for oxygenating the same; means establishing a blood
flow path from said oxygenator to one of said connecting means; a
blood pump; means establishing a blood flow path from the other of
said connecting means to said blood pump, said blood pump being
adapted to conduct oxygenated blood to the patient and further
being a positive displacement pump whereby a slight vacuum may be
pulled upstream of the same so that the absence of blood flowing
from said oxygenator to said valve will result in said valve
closing to preclude the pumping of air into the arterial system of
the patient.
2. The blood oxygenating system of claim 1 wherein said inner
membrane wall has a length equal to about at least ten times the
cross sectional dimension of said tube; said closed space has a
volume at least slightly greater than the volume of the interior of
said tube along the length of the inner membrane wall; and the
liquid in said closed space is a biologically harmless liquid.
3. A blood oxygenating system according to claim 2 wherein said
connecting means comprise barbed, tubular extensions on both ends
of said tube.
Description
BACKGROUND OF THE INVENTION
This invention relates to perfusion safety valves particularly
suited for use in blood oxygenating systems.
The continuing progress of medical science has resulted in highly
complicated surgical procedures becoming relatively commonplace.
One class of such procedures involves the use of heart lung
machines or the like wherein blood is removed from the venous
system of a patient, oxygenated and returned to the arterial system
of the patient. Typically, structures known as oxygenators are
employed in such procedures and require monitoring by trained
personnel to insure that blood in the oxygenating system will not
be exhausted with the result that air might be pumped into the
patient to cause air embolism, a condition frequently resulting in
death. As a safeguard against inattentiveness of an attendant
monitoring the blood level in the oxygenating system, it is
desirable to provide means for automatically cutting off the flow
of blood should blood reach a predetermined degree of exhaustion to
preclude the pumping of air into the patient, such as a valve.
SUMMARY OF THE INVENTION
It is a principal object of the invention to provide a new and
improved perfusion safety valve for receipt in a blood oxygenating
system that is responsive to exhaustion of blood in an oxygenator
or the like to automatically stop the flow of fluid through a line
leading to the patient to preclude the pumping of air into the
patient's arterial system and the attendant catastrophic results.
More particularly, it is an object of the invention to provide such
a valve that is inexpensive to manufacture, is positive in its
action without requiring the use of equipment peripheral to that
employed in the oxygenating system to perform its function, and
which may be disposed of after a single use if desired.
The exemplary embodiment of the invention achieves the foregoing
objects by means of a construction employing an elongated,
perforated, rigid tube. About the entire inner periphery of the
tube there is provided a flexible, blood compatible membrane, while
exteriorly of the tube, a generally similar membrane is provided.
The two membranes are arranged with respect to each other and to
the tube such that the closed space between the two membranes
having a volume at least slightly greater than the volume of the
interior of the tube results. The close space is filled with a
biologically harmless liquid such as a saline solution.
When employed in an oxygenating system, the typical positive
displacement pump for the blood line is located downstream of the
valve, and the valve is located downstream of an oxygenator or the
like. Normally, the head of the blood in the oxygenator will be
sufficient to maintain the inner membrane in substantial abutment
with the interior wall of the tube so that blood may flow
therethrough. When the head decreases to a certain value, the
slight vacuum pulled by the pump will result in atmospheric
pressure being applied to the outer membrane forcing the liquid in
the closed space through the perforations into the tube to the
interface between the interior of the tube and the inner membrane
thereby causing the latter to collapse upon itself to terminate the
flow of fluid through the line.
Thus, the construction requires no operating components other than
the positive displacement pump used in the oxygenating system
itself and should the same fail, it will be obvious that there
would be no chance of air embolism by reason of the ceasing of the
pumping action. This is in contrast to an arrangement wherein
exterior equipment might be employed to control the valve position
which equipment could fail while the pump continued in operation,
in which case, the valve would be ineffective.
For ease of use, barbed tubular extensions are secured to opposite
ends of the tube for connection into typical plastic blood conduit
tubing employed in such systems.
Other objects and advantages will become apparent from the
following specification taken in conjunction with the accompanying
drawings.
DESCRIPTION OF THE DRAWINGS
FIG. 1 is a flow diagram illustrating a typical oxygenating system
with which the inventive valve is designed to be employed;
FIG. 2 is a sectional view of a valve made according to the
invention showing the component parts when the valve is open;
FIG. 3 is a sectional view of the valve in a closed condition;
FIG. 4 is a cross section of the valve in an open condition;
and
FIG. 5 is a cross section of the valve in a closed condition.
DESCRIPTION OF THE PREFERRED EMBODIMENT
One typical system in which a valve made according to the invention
is intended to be used is illustrated in schematic form in FIG. 1
and is seen to include a conventional blood oxygenator 10 adapted
to receive venous blood from a patient 12. Downstream of the
oxygenator 10, and physically below the oxygenator is a perfusion
safety valve, generally designated 14, so that a head of blood is
applied thereto. Downstream of the valve 14 is a positive
displacement pump 16 which, in turn, provides oxygenated blood to
the arterial system of the patient. As will be seen, the physical
location of the valve 14 with respect to the oxygenator 10 is of
some significance insofar as the valve in part responds to the lack
of establishment of a predetermined head of blood applied thereto.
This factor, coupled with the slight vacuum pulled by the positive
displacement pump 16, will cause the valve 14 to close if the blood
in the oxygenator reservoir 10 becomes exhausted.
Turning now to FIG. 2, an exemplary embodiment of the valve 14 is
illustrated in cross section. The valve 14 comprises an elongated,
rigid tube 18 which may be formed of polycarbonate, methacrylate or
similar plastic. The tube 18 is perforated as at 20 (additional
perforations 20 may be located along virtually the entire length of
the tube 18, if desired) and includes internal steps 22 at its
ends.
Within the tube 18 is a circumferential membrane film 24 defining a
blood impermeable wall. The membrane 24 is sufficiently flexible so
that the same may collapse upon itself within the interior of the
tube to cut off the flow of fluid therethrough and is formed of any
suitable blood compatible material such as silicone rubber or a
polyvinyl plastic.
Exteriorly of the tube 18 is a second peripheral membrane film 26,
also formed of any suitable flexible material. The membranes 24 and
26 define a closed space 28 having a volume at least slightly
greater than the volume of the interior of the tube 18 between the
ends of the membranes 24 and 26 (and in the embodiment illustrated
in FIGS. 2 and 3, the ends of the tube 18) and which is adapted to
receive biologically harmless liquid such as a saline solution. If
desired, the outer film 26 may be provided with a suitable sealable
port (not shown) for the purpose of introducing a liquid into the
closed space 28.
The ends of the membrane 26 are sealingly secured to the ends of
the tube 18 in any suitable fashion to partially define the closed
space 28 while the ends of the membrane 24 may be received in the
steps 22 of the tube 18. To maintain the same in sealed engagement
therewith, any suitable means such as an adhesive may be employed
or, in the alternative, for the two-fold purpose of establishing
sealing engagement between the membrane 24 and the tube 18 and to
facilitate connection of the latter into blood conduit tubing,
tubular extensions 30 having complementary steps 32 may be received
in the steps 22 and secured thereto to sealingly hold the ends of
the membrane 24 thereagainst. The extensions 30 include barbed ends
34 for receipt into conventional plastic tubing employed in the
blood line.
In operation, a suitable conduit from the oxygenator 10 will be
secured to one of the barbed extensions 30 while the conduit to the
pump 16 will be secured to the other barbed extension 30. As long
as the head of blood within the oxygenator reservoir exceeds a
predetermined level, the pressure of the same will maintain the
membrane 24 in the position illustrated in FIGS. 2 and 4 so that
blood may pass through the valve 14 to the pump 16 and then to the
patient 12. However, should the head of blood in the reservoir fall
below the desired level, the slight vacuum pulled by the pump will
result in the atmospheric pressure applied to the outer membrane 26
collapsing the same driving the saline solution within the closed
space 28 through the perforations 20 to force the inner membrane 24
to seal upon itself as illustrated in FIGS. 3 and 5 to halt the
flow of fluid through the line while at least a minimal quantity of
blood remains therein to preclude any possibility of air
embolism.
According to one embodiment of the invention, the internal diameter
of the tube 18 is about three-eighths of an inch while the length
of the surface of the inner membrane 24 that may collapse upon
itself will be at least ten times that length so that the
capability of sealing upon collapse is enhanced. For a typical
construction, this would require a length on the order of 4 to 6
inches.
From the foregoing, it will be appreciated that a valve made
according to the invention does not require operating equipment
other than that found in the oxygenating system itself so that
system failure cannot be occasioned by failure of peripheral
equipment. Moreover, the simplicity of construction coupled with
positive action results in an inexpensive construction that is
completely reliable and one which may be disposed of after a single
use.
* * * * *