U.S. patent number 3,708,110 [Application Number 05/061,574] was granted by the patent office on 1973-01-02 for container for blood.
This patent grant is currently assigned to AGA Aktiebolag. Invention is credited to Gunnar Ingemar Berndtsson, Stephan Lars Schwartz, Hans Peter Olaf Unger, Johan Eric Hayden Westberg.
United States Patent |
3,708,110 |
Unger , et al. |
January 2, 1973 |
CONTAINER FOR BLOOD
Abstract
A container for blood is provided in which blood received from a
patient can be stored and processed without the necessity of being
transferred to another container. For example, the blood can be
centrifuged, frozen or transfused without the necessity of being
transferred to another container. The container comprises a closed
annular flexible container of a flexible material which is inert to
blood and which is provided with at least one opening for the
passage of blood into and out of the annular container. The
flexible material may be enclosed in an inflexible material.
Inventors: |
Unger; Hans Peter Olaf
(Stockholm, SW), Westberg; Johan Eric Hayden
(Lidingo, SW), Berndtsson; Gunnar Ingemar (Stockholm,
SW), Schwartz; Stephan Lars (Lidingo, SW) |
Assignee: |
AGA Aktiebolag (Lidingo,
SW)
|
Family
ID: |
20293394 |
Appl.
No.: |
05/061,574 |
Filed: |
August 6, 1970 |
Foreign Application Priority Data
|
|
|
|
|
Aug 11, 1969 [SW] |
|
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11122/69 |
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Current U.S.
Class: |
494/45; 383/907;
494/27; 604/408; 383/904; 422/44; 494/43 |
Current CPC
Class: |
A61M
5/14 (20130101); A61J 1/05 (20130101); Y10S
383/904 (20130101); Y10S 383/907 (20130101) |
Current International
Class: |
A61J
1/00 (20060101); A61M 5/14 (20060101); B04b
009/12 () |
Field of
Search: |
;128/214D,214.2,272,276
;233/1E,20,26,27 ;150/2.1-2.4 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Truluck; Dalton L.
Claims
What is claimed is:
1. In combination, a centrifuge having a rotor and, disposed about
said rotor in said centrifuge, an annular container for holding
blood during rotation of said centrifuge, said annular container
being made of a flexible material and comprising a hollow annular
chamber formed by two annular side walls spaced apart a short
distance and by two transverse end walls extending between and
joining the edges of said annular sides thus forming said chamber,
the central area of said container within the annular chamber being
open such that the annular container is disposable about said
rotor, and said annular container including a tube attached to the
end wall of said container adjacent the open central area of the
container for conveying blood into and out of said annular
container.
2. The combination according to claim 1 wherein said container
includes an outer portion of non-flexible material totally
enclosing said flexible annular container.
3. The combination according to claim 1 wherein said outer wall is
formed by the outer edges of said annular sides being bent towards
one another and joined to each other.
4. An annular container for holding blood during centrifuging, said
container being made of flexible material and comprising a hollow
annular chamber formed by two annular side walls spaced apart a
short distance and by two transverse end walls extending between
and joining the edges of said annular sides thus forming said
chamber, the central area of said container within the annular
chamber being open such that the annular container is disposable
about a centrifuge rotor, said annular container including a tube
attached to the end wall of said container adjacent the open
central area of the container for conveying blood into and out of
said annular container, said chamber being conical such that the
container is adapted to bear against a conical member in a
centrifuge during centrifuging.
Description
BACKGROUND OF THE INVENTION
The invention relates to a container for blood, which is
particularly suitable for use in connection with centrifuging,
freezing, transfusion and the like.
In the handling of blood it is of great importance that sterility
should be maintained during the various processes which the blood
has to undergo. It is desirable therefore that the same container
should be used for different processes so as to avoid transfer of
the blood.
It is an object of the present invention to provide a container
which is suitable for all processes which are put into practice in
today's blood-giving activities without the necessity of
transferring the blood from one container to another. It is a
further object of the invention to provide a method of storing
blood which avoids the necessity of transferring blood from one
container to another for processing the blood such as by freezing,
centrifuging, and the like.
BRIEF SUMMARY OF THE INVENTION
The foregoing and other objects which will be apparent to those
having ordinary skill in the art are achieved according to the
present invention by providing a container for blood which avoids
the necessity of transferring the blood from one container to
another for centrifuging, freezing, transfusion, and the like which
comprises a closed annular container of a flexible material which
is inert to blood and which is provided with at least one opening
for the passage of blood into and out of said container.
DETAILED DESCRIPTION
There follows a detailed description of a preferred embodiment of
the invention, together with accompanying drawings. However, it is
to be understood that the detailed description and accompanying
drawings are provided solely for the purpose of illustrating a
preferred embodiment and that the invention is capable of numerous
modifications and variations apparent to those skilled in the art
without departing from the spirit and scope of the invention.
FIG. 1 is a schematic elevation view, in section, of a container
according to the invention;
FIG. 2 is a schematic elevation view, in section, of an alternative
container according to the invention;
FIG. 3 shows how the container according to FIG. 1 can be used in
blood transfusion; and
FIG. 4 is a radial elevation section of a centrifuge according to
co-pending application Ser. No. 61,583, filed Aug. 6, 1970 showing
the use of several containers according to the present
invention.
The container shown in FIG. 1 is annular and has broadly speaking
the shape of a disc, the disc being formed by an outer wall 1 and
an inner wall 2 with an opening 3 in the center. The disc is
conical in section. At the inner portion of the annular container,
a tube 4 is connected which serves for the feed and discharge of
blood to and from the same. The outer and inner wall 1 and 2
respectively are joined together at their inner edges by a
transverse wall 5, and at their outer edges 6 the two walls 1 and 2
are bent together and welded together, so that a closed annular
container is obtained. In place of the single tube 4 shown, a
plurality of such connecting tubes may be arranged, distributed in
a suitable manner along the periphery of the inner wall 5 of the
annular container.
The walls of the container are inert to blood and may be of laminar
construction with an inside layer of a material that is harmless to
blood, such as Teflon or polyethylene, and an outer layer of strong
material with mechanical strength and freezing resistance, for
example nylon.
The annular shape of the container shown in suitable and practical
for centrifuging and for other treatment of the blood. The annular
form represents a shape which can easily be adapted to a
centrifuge, the central portion of which can pass through the
opening in the center of the container. Moreover, owing to its
flexibility, the container is suitable for application in
transfusion, since it can readily be brought to the shape shown in
FIG. 3 for delivery of the blood contained in it, leaving behind
only a negligible residue.
In the modified embodiment according to FIG. 2 there is an inner
flexible container 7 and an inflexible outer portion 8 enclosing
the flexible container and consisting of a bottom portion 8' with a
lid 8" placed therein. The inner portion 7 in its relaxed condition
may have a shape as shown in FIG. 2 or the shape which is shown in
FIG. 1. In the latter case the shape shown in FIG. 2 is obtained
through deformation when the inner portion 7 is placed in the outer
portion 8. The latter is of rigid material such as rigid plastic
and of a suitable annular shape so as to enclose the inner portion
7 without forming a space between inner and outer portion. If the
rigid material has good thermal conductivity, the container
according to FIG. 2 is suitable for freezing of blood. The rigid
outer portion can be given an appropriate volume corresponding to
the quantity of blood usually occurring in transfusions.
FIG. 3 shows a container in accordance with FIG. 1 or an inner
portion of a container according to FIG. 2 in position to be used
in blood transfusion. Owing to its flexibility, container 9 can be
inserted in a transfusion bucket 10, in the bottom of which is a
hole 11 through which the tube 4 can be conducted for connection to
the patient.
The container has particular utility in a centrifuge of the type
described in U.S. application Serial No. 61,583 filed August 6,
1970 which is incorporated herein by reference.
Utilization of several containers in a centrifuge is illustrated in
FIG. 4. The centrifuge comprises a rotating chamber 12 containing a
compressible container 13 according to the invention for the liquid
to be centrifuged. The centrifuge also includes means 14 to
compress the container against conical member 19 to transfer liquid
from the container during centrifugation. The compressing means is
also capable of compressing one or more further compressible
containers 15, 16, 17 according to the invention to transfer liquid
therefrom to the first-mentioned compressible container 13. The
compressing means is preferably a diaphragm member which is urged
by centrifugal force against a compressible container. In one
application, container 13 is filled with blood to be centrifuged
and, after the serum is separated by rotation of chamber 12 about
the axis of rotor 18 a valve is opened permitting the diaphragm to
compress container 13 to transfer the serum to a further container
15. The valve is then closed and speed reduced until the diaphragm
returns to its rest position causing compression of a still further
container 17 provided with wash water. A valve is then opened to
permit transfer of some or all of the wash water into the
first-mentioned container 13 and the device may then be braked to
cause the water to mix with the blood cells therein. The washed
blood cells are then centrifuged and the water transferred to the
water container 17 or yet a still further container 16 by the
actuation of an appropriate valve similarly as in the case of
transferring the serum. The washing operation is repeated if
desired until all of the wash water has been utilized.
* * * * *