U.S. patent number 3,705,582 [Application Number 04/860,223] was granted by the patent office on 1972-12-12 for breech loaded syringe and method of breech loading same.
Invention is credited to Elmer A. Koenig, Marvin D. Stumpf.
United States Patent |
3,705,582 |
Stumpf , et al. |
December 12, 1972 |
BREECH LOADED SYRINGE AND METHOD OF BREECH LOADING SAME
Abstract
A syringe wherein a piston is moved axially through a tubular
barrel to deliver liquid medicament and the like outwardly through
a needle connected through an inner end of the barrel. A control is
provided for selectively deforming the piston to permit the barrel
to be preloaded with the liquid medicament through the breech end
thereof with the piston being brought into engagement with the
liquid while a fluid bypass passage is provided around the piston
to the breech end of the barrel, thereby to vent air outwardly from
the space between the piston and the liquid medicament during the
insertion of the piston.
Inventors: |
Stumpf; Marvin D. (St. Louis,
MO), Koenig; Elmer A. (Kirkwood, MO) |
Family
ID: |
25332754 |
Appl.
No.: |
04/860,223 |
Filed: |
September 23, 1969 |
Current U.S.
Class: |
604/506; 53/320;
604/218; 53/57; 604/121 |
Current CPC
Class: |
A61M
5/31511 (20130101) |
Current International
Class: |
A61M
5/315 (20060101); A61m 005/00 () |
Field of
Search: |
;128/218R,218P,218M,220
;53/57 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Reich; Joseph S.
Claims
I claim:
1. In a syringe having a tubular barrel defining a chamber opening
axially through the outer end of the barrel, and a needle
connecting portion at the inner end of the barrel for connecting a
needle in fluid flow association with said chamber, the improvement
comprising:
a resilient piston arranged to have sealing sliding engagement with
the barrel in said chamber; first means secured to said piston and
extending from said piston to outwardly of said outer end for
moving said piston into said chamber through said outer end during
insertion thereof in said barrel and for moving said piston to
discharge fluid from said chamber in response to a manually applied
force on said first means during operational use of the syringe;
and second means carried by said first means and extending from
within said chamber to outwardly of said outer end, said second
means being movable in one direction relative to said first means
to deform said piston
for forming fluid bypass means around said piston for venting the
chamber portion forward of said piston, and movable in the
direction opposite said one direction relative to said first
means
for removing the fluid bypass means whereby the piston sealingly
engages with the barrel to force fluid from said chamber through
said needle connecting portion as an incident of movement of said
piston in said chamber toward said inner end in response to said
applied force on said first means.
2. In a syringe having a tubular barrel defining a chamber opening
axially through the outer end of the barrel, and a needle
connecting portion at the inner end of the barrel for connecting a
needle in fluid flow association with said chamber, the improvement
comprising:
a resilient piston arranged to have sealing sliding engagement with
the barrel in said chamber;
first means secured to and extending from said piston to outwardly
of said outer end for manipulating said piston during operational
use of the syringe; and
second means carried by said first means, said first and second
means being relatively movable
a. for forming fluid bypass means around said piston for venting
the chamber portion forward of said piston, and
b. for removing the fluid bypass means whereby the piston is in
sealing engagement with the barrel to force fluid from said chamber
through said needle connecting portion as an incident of movement
of said piston in said chamber toward said inner end, said second
means comprising means having a tubular inner end removably
receiving said piston, and means for causing axial removal of said
piston from said tubular inner end, said second means having a
clearance with said barrel defining said fluid bypass means to said
outer end of the barrel, said second means also having an axially
inner end for retaining the piston axially inwardly of said tubular
end subsequent to said removal.
3. In a syringe having a tubular barrel defining a chamber opening
axially through the outer end of the barrel, and a needle
connecting portion at the inner end of the barrel for connecting a
needle in fluid flow association with said chamber, the improvement
comprising:
a resilient piston arranged to have sealing sliding engagement with
the barrel in said chamber;
first means secured to and extending from said piston to outwardly
of said outer end for manipulating said piston during operational
use of the syringe; and
second means carried by said first means and extending from within
said chamber to outwardly of said outer end, said first and second
means being selectively relatively movable.
a. for forming fluid bypass means around said piston for venting
the chamber portion forward of said piston, and
b. for removing the fluid bypass means whereby the piston is in
sealing engagement with the barrel to force fluid from said chamber
through said needle connecting portion as an incident of movement
of said piston in said chamber toward said inner end in response to
an applied force on said first means, said second means comprising
means removably extending the length of said piston between said
piston and said barrel for deforming said piston to form a
plurality of fluid bypass passages between the deformed piston and
the barrel which communicate with said outer end of the barrel,
said passages defining said fluid bypass means, said second means
comprising a plurality of angularly spaced elements providing said
fluid bypass means.
4. In a syringe having a tubular barrel defining a chamber opening
axially through the outer end of the barrel, and a needle
connecting portion at the inner end of the barrel for connecting a
needle in fluid flow association with said chamber, the improvement
comprising:
a resilient piston arranged to have sealing sliding engagement with
the barrel in said chamber;
first means extending from said piston to outwardly of said outer
end for manipulating said piston during operational use of the
syringe; and
second means carried by said first means and extending from within
said chamber to outwardly of said outer end, said first and second
means being selectively relatively movable
a. for forming fluid bypass means around said piston for venting
the chamber portion forward of said piston, and
b. for removing the fluid bypass means whereby the piston is in
sealing engagement with the barrel to force fluid from said chamber
through said needle connecting portion as an incident of movement
of said piston in said chamber toward said inner end, said second
means comprising a tubular element having an axial bore provided
with a portion at the inner end of said tubular element of greater
diameter than other portions of said bore for receiving said
piston, said tubular element removably extending the length of said
piston between the piston and said barrel for deforming the piston
to define said fluid bypass means between the deformed piston and
the barrel which communicate with said outer end of the barrel.
5. The method of filling a syringe having a barrel with a bore open
at the breech end of the barrel for receiving a liquid medicament
during the filling of the syringe, and a shaft and piston assembly
comprising a resilient piston for sliding sealing engagement with
the barrel in the bore, and a shaft connected to the piston and
responsive to an applied force thereon for moving the piston toward
the inner end of the barrel to discharge the medicament from the
bore during operational use of the syringe comprising the steps
of:
providing said shaft and piston assembly with a relatively movable
elongate member adapted to deform said piston upon movement thereof
in one direction relative to said shaft;
moving said elongate member in said one direction relative to said
shaft to deform said piston;
inserting said piston and shaft assembly and said elongate member
into the bore through the breech end thereof;
moving the shaft and piston assembly and elongate member toward the
inner end of the barrel with said piston deformed to provide fluid
bypass means within the barrel from a point ahead of said piston to
said breech end for venting air from the barrel as said piston is
moved toward the liquid medicament; and moving said elongate member
in the direction opposite said one direction relative to said shaft
to cause said piston to have sealed sliding engagement with the
barrel.
6. The method of filling a syringe with liquid medicament of claim
5 wherein substantially the entire piston is deformed away from
contact with the barrel during the step of moving the shaft and
piston assembly and the elongate member toward the inner end of the
barrel.
7. The method of filling a syringe with liquid medicament of claim
5 wherein only a portion of the piston is deformed away from
contact with the barrel during the step of moving the shaft and
piston assembly and the elongate member toward the inner end of the
barrel.
8. The method of filling a syringe with liquid medicament of claim
5 wherein the step of moving said second means in said one
direction relative to said first means to deform said piston is
performed prior to the step of inserting said shaft and piston
assembly into the breech end of the barrel, and said piston is
maintained deformed by said elongate member until it is
substantially moved to the liquid medicament.
Description
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to syringes and in particular to piston-type
syringes.
2. Description of the Prior Art
In the conventional piston syringe, the filling of the syringe is
effected through the needle connecting end. Such a method of
filling the syringe is undesirable where the filled syringe is to
be stored, such as where the syringe comprises a prefilled syringe.
Further, such needle end filling is inimical to good aseptic
techniques. Illustratively, it has been found that the narrow
lumens of the needle or needle connector tip become clogged by the
dried medicament.
One attempted method of resolving this problem has been to load the
syringe through the breech end of the barrel. Such a loading of the
syringe provides improved storage characteristics where air is
removed from between the piston and liquid medicament upon
insertion of the piston. Thus, in the prior art devices for
providing such breech loading, needles, rods, valves, conical
shaped sleeves, etc. have been employed to permit venting of the
trapped air. Not only are such means relatively expensive, but
also, such means have been found to lead to contamination of the
liquid medicament.
SUMMARY OF THE INVENTION
The present invention comprehends an improved syringe structure
wherein the piston, during insertion through the breech end of the
barrel into engagement with the previously deposited liquid
medicament, is deformed so as to provide a bypass vent. The
deforming means may comprise a tubular element adapted to receive
the piston under compression and having a clearance with the barrel
permitting movement of the inner end of the element through the
breech end of the barrel into juxtaposition with the liquid
medicament wherein the trapped air is vented through the clearance
space between the sleeve and the barrel. Upon reaching the fully
inserted position, the piston is removed from its position within
the sleeve end thereby permitting the piston to expand into sealed
sliding engagement with the barrel wall. The piston may be carried
on the inner end of a shaft extending from the piston to outwardly
of the barrel outer end.
In one specific embodiment of the invention, the shaft extends
coaxially through a tubular sleeve having a bore radially enlarged
at its inner end to define a piston receiving recess. The tubular
sleeve also has a recess at its outer end for receiving in nested
relationship the thumb piece of the shaft. Movement between the
shaft and the sleeve may be effected manually to provide the
selective deformation and release of the piston.
Alternatively, the piston may be deformed by a rib element on the
inner end of the sleeve which extends the length of the piston to
deform an outer wall portion thereof radially inwardly and thereby
form a fluid bypass passage permitting the air to be vented from
the barrel during the insertion of the piston. If desired, a
plurality of such rib elements may be provided to form a plurality
of such bypass passages for venting during the piston insertion
step.
Thus, the invention comprehends an improved method of filling a
syringe with liquid medicament including the steps of introducing
the liquid medicament through the breech end of the syringe barrel,
inserting a resilient piston through the breech end while
concurrently deforming the piston to define a fluid bypass passage
around the piston to the breech end for venting air from the barrel
as the piston is moved to the liquid medicament, and discontinuing
the deforming of the piston upon the piston reaching the liquid
medicament to cause the piston to have sealed sliding engagement
with the barrel. The filling of the syringe may be effected to
provide a prefilled syringe unit which may be stored for subsequent
use as desired. In such case, the needle end of the syringe is
maintained sealingly closed. Alternatively, the syringe will be
breech filled at the time of use by the above indicated steps.
BRIEF DESCRIPTION OF THE DRAWING
Other features and advantages of the invention will be apparent
from the following description taken in connection with the
accompanying drawing wherein:
FIG. 1 is a fragmentary enlarged front view of a syringe embodying
the invention with portions broken away to illustrate the
invention;
FIG. 2 is a view similar to that of FIG. 1 but illustrating the
arrangement of the syringe during the piston inserting
operation;
FIG. 3 is an exploded view with portions broken away illustrating
the arrangement of the piston and sleeve assembly prior to
insertion into the syringe barrel;
FIG. 4 is a front view of one form of sleeve thereof;
FIG. 5 is a fragmentary bottom end view thereof;
FIG. 6 is a front view of the sleeve used in the syringe shown in
FIGS. 1-3, with a portion broken away to provide a clear
illustration of the invention;
FIG. 7. is a bottom end view of the sleeve of FIG. 6;
FIG. 8 is a front view of still another modified form of sleeve
thereof with a portion broken away to illustrate the invention;
and
FIG. 9 is a bottom end view of the sleeve of FIG. 8.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
In the exemplary embodiment of the invention as disclosed in FIGS.
1-3 of the drawing, a syringe generally designated 10 is shown as
having a conventional tubular barrel 11 defining a chamber 12
opening axially outwardly through an outer end 13. The inner end 14
of the barrel 11 is provided with an outlet 15 opening into a
connector 16 for attaching a needle, such as conventional needle
17, in fluid transfer association with the inner end of the barrel.
In the illustrated embodiment, the connector comprises a
conventional luer lock connector, it being understood that any
suitable needle connecting means may be utilized. Prior to the
installation of the needle 17 onto the connector 16, connector 16
may be conventionally closed by a conventional cap 18, as shown in
FIGS. 2 and 3.
The syringe 10 may comprise a prefilled syringe wherein a body of
liquid, such as liquid medicament 19, is provided in the portion 20
of the chamber 12 inwardly of a piston 21. In the illustrated
embodiment, the liquid 19 is delivered into the chamber 12 through
the outer end 13 in a breech loading operation. The piston 21 is
then brought into the chamber 12 through the outer end 13 to engage
the liquid 19 as shown in FIG. 2. To permit such insertion of the
piston, a bypass passage 22 is provided around the piston from the
inner chamber portion 20 to the outer opening 13 whereby air may be
vented from the chamber 12 as the piston is moved downwardly
therethrough to the position of FIG. 2.
The invention comprehends the provision of the vent passage 22 by
means of a tubular element, or sleeve, 23 having an outside
diameter slightly smaller than the inside diameter of the barrel
11. The bore 24 of sleeve 23 is stepped at 25 to define a radially
enlarged inner end bore portion 26 adapted to receive the piston 21
as shown in FIG. 2. Piston 21 is preferably formed of a resilient
material, such as neoprene rubber, to permit the ready compression
thereof into the bore portion 26 of the sleeve 23 as by urging the
sleeve axially forward relative to the piston 21 until the piston
is encased in portion 26 as shown in FIG. 3. The piston is secured
to an end connector portion 27 of a shaft 28 having an outer thumb
piece 29. Shaft 28 extends coaxially through the bore 24 of sleeve
23. As shown in FIG. 2, shaft 28 is somewhat smaller in transverse
dimension than the diameter of bore 24, permitting the ready axial
movement of the shaft 28 therethrough when desired. To provide
relative movement between the shaft 28 and sleeve 23 and to provide
for the movement of the sleeve 23 into the barrel 11, the outer end
of the sleeve is provided with a flange 30. Flange 30 is spaced
outwardly of the conventional outturned flange 31 of the barrel to
permit the user to insert his fingers under flange 30 with his
thumb on thumb piece 29 and thereby readily effect a movement of
the piston 21 inwardly from the end portion 26 when desired. Thus
by maintaining the piston 21 in contact with the liquid medicament
19 and urging the sleeve 23 outwardly, the lower end of the sleeve
is withdrawn from the piston permitting the piston to expand
radially into sliding sealing engagement with the barrel wall in
bore portion 20 thereby to permit subsequent controlled delivery of
the liquid medicament outwardly through needle 17 as desired.
The flange 30 of the sleeve 23 has a recess 35 formed in the upper
surface 32 which recess 35 is of a size and shape to receive in
nested relationship the thumb piece 29 of the shaft 28 when the
shaft is fully depressed relative to the sleeve 23. In moving the
shaft 28 relative to the sleeve 23 from the position of FIG. 2 to
the position of FIG. 1, the thumb piece 29 will nest in the recess
35 and create the appearance of a one piece plunger unit.
In the normal use, the piston 21 may be provided retracted within
bore portion 26 as shown in FIG. 3, permitting the movement of the
assembled piston and sleeve 23 into the barrel 11 as discussed
above. However, alternatively, the piston may be mounted on the
shaft end 27 inwardly of the sleeve (in the arrangement seen in
FIG. 1) and inserted into the open end 13 of the barrel 11. The
piston is then caused to move into the bore portion 26 by a
combination of forces directed by the user's fingers on the outer
surface 32 of the flange 30 and the fluid pressure within the bore
12 ahead of the piston 21 thereby to cause the piston to move
axially into the sleeve bore end 26. Once the piston is fully
received in bore end 26, further movement of the assembly may be
effected as discussed above as the sleeve and piston structure are
now disposed in the arrangement shown in FIG. 2. This method of
bringing the piston into the bore end 26 at the time of assembly is
advantageous where the piston 21 is formed of a material which may
take a permanent set if stored within the sleeve bore 24 for a
protracted period of time. The piston 21, sleeve 23, and shaft 28
may, of course, be assembled together by inserting the shaft 28
through the sleeve 23, and then mounting the piston 21 onto the
inner end 27 of the shaft so that these parts occupy the relative
positions shown in FIG. 1. The piston is deformed to provide a vent
passage around the piston 21 by effecting relative movement between
the shaft with the piston connected thereto, and the sleeve. In the
illustrated embodiment of FIGS. 1-3, such relative movement
positions the piston 21 in the sleeve bore end 26 and this effects
deformation of the piston by urging peripheral portions thereof
radially inwardly, the piston being retained in the bore end 26 by
the inherent resiliency thereof.
Thus, the syringe 10 provides an improved structure permitting
prefilling of the syringe in an aseptic manner by a breech loading
of the liquid medicament therein. As indicated above, the liquid
medicament may be retained in the prefilled syringe by the
subsequent installation of the piston 21 as discussed above,
whereby the piston may be brought into engagement with the upper
surface of the liquid by a vented movement of the piston through
the barrel, thereby maintaining the aseptic condition of the breech
loaded syringe. When the syringe is to be used, the cap 18 is
removed and the needle 17 installed on the connector 16 in the
conventional manner whereupon the liquid medicament may be
delivered through the needle by suitable manipulation of the shaft
28 by the user's fingers engaging flange 31 and thumb piece 29.
The invention comprehends broadly providing a means for deforming
the piston 21 during its insertion through the bore 12 to define a
bypass passage 22 whereby the bore 12 is vented to facilitate the
movement of the piston fully to the position of FIG. 2. As
discussed above, in one form, the means for forming the bypass
passage 22 may comprise means for receiving the piston under
compression within one end of the tubular sleeve 23. The sleeve
construction is illustrated in FIGS. 6 and 7. As will be obvious to
those skilled in the art, other forms of piston deforming means may
be provided within the scope of the invention. Illustratively, in
FIG. 4, a sleeve 123 is shown to comprise a sleeve similar to
sleeve 23 but having a plurality of circumferentially spaced end
prongs 133 which effectively distort the piston when the piston is
retracted into the space 126 radially within the prongs. In the
illustrative embodiment of FIG. 4, three such prongs are provided
spaced 120.degree. about the axis of the sleeve. In FIGS. 8 and 9,
a further modified form of sleeve 223 is shown to comprise a sleeve
having a depending prong 223 provided with a radially inwardly
projecting rib 234 which effectively distorts the piston to define
an air bypass vent passage for venting the barrel during the
installation of the piston.
Each of the sleeves 23, 123, and 223 is similar to the others and
functions in a similar manner except as otherwise noted. In each
embodiment, means are provided for deforming the piston during
insertion thereof into the barrel bore to define a vent passage.
The deforming means are carried on an elongated element which
extends to outwardly of the barrel serving as a means for effecting
a separation of the deforming means from the piston after the
piston reaches the desired fully inserted position whereby the
piston may then function in the normal manner within the barrel. As
will be obvious to those skilled in the art, the element carrying
the deforming means may have other configurations in addition to
the tubular sleeve configuration of the illustrative embodiments.
The different parts of these syringes may be made of suitable
materials, such as plastics, permitting relative ease of
sterilization. Thus, the syringes may comprise one-time use,
prefilled syringes.
The foregoing disclosure of specific embodiments is illustrative of
the broad inventive concepts comprehended by the invention.
* * * * *