U.S. patent number 3,678,931 [Application Number 05/044,742] was granted by the patent office on 1972-07-25 for syringe.
Invention is credited to Milton J. Cohen.
United States Patent |
3,678,931 |
Cohen |
July 25, 1972 |
SYRINGE
Abstract
A syringe formed of inner and outer tubular members with the
inner member adapted to be telescoped within the outer member and
sealed therefrom by a sealing assembly comprising a disc member
having at least one opening therethrough communicating with the
inner tubular member and a flexible seal having a disc portion
having openings therethrough, with the openings in the disc member
being laterally offset from the opening in the disc portion, while
the outer member is formed with a rupturable seal having an
injection needle in alignment therewith for rupture in use with the
inner tubular member adapted to contain a liquid carrier and the
outer tubular member adapted to carry a solid medicant to be taken
up with the carrier for injection whereby the materials are freshly
mixed immediately prior to injection.
Inventors: |
Cohen; Milton J. (Chevy Chase,
MD) |
Family
ID: |
21934078 |
Appl.
No.: |
05/044,742 |
Filed: |
June 9, 1970 |
Current U.S.
Class: |
604/90;
604/201 |
Current CPC
Class: |
A61M
5/284 (20130101); B05C 17/00593 (20130101); A61M
2005/31598 (20130101); A61M 5/288 (20130101); B05C
17/00516 (20130101) |
Current International
Class: |
A61M
5/28 (20060101); A61M 5/315 (20060101); A61m
005/00 () |
Field of
Search: |
;128/218M,220,218P,2.8PA,234 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Mancene; Louis G.
Assistant Examiner: Weinhold; D. L.
Claims
I claim:
1. In a syringe assembly including inner and outer tubular members
with the inner tubular member having an outer wall-to-wall
dimension less than the inner wall-to-wall dimension of the outer
tubular member to enable the inner tubular member to be telescoped
within the outer tubular member, a rupturable closure sealing the
forward end of the outer tubular member, a hypodermic needle, means
supporting said needle to permit said needle to penetrate said
rupturable closure in response to insertion of said needle, a
piston plug dimensioned to be slidably received within the inner
tubular member, and means to actuate the piston plug axially
relative to the inner tubular member, the improvement comprising a
flexible seal sealing the forward end of the inner tubular member,
said seal comprising a piston ring portion on the forward end of
the forward end of the inner tubular member in sliding engagement
with the inner walls of the outer tubular member and a flexible
disc portion having at least one opening therethrough communicating
with the outer tubular member, and a disc member having at least
one opening therethrough communicating with the inner tubular
member, said disc portion overlaying said disc member in a sealing
relation on the forward end of the inner tubular member and the
opening in said disc member being laterally offset from the opening
in said disc portion whereby said disc portion is flexed in
response to an internal pressure within said inner tubular member
and transmitted through the opening of the disc member to permit
the flow of a fluid in the inner tubular member through the
openings in said disc member and said disc portion to the outer
tubular member.
2. A syringe as defined in claim 1 which includes a removable cover
for the needle.
3. A syringe as defined in claim 1 in which the inner tubular
member is adapted to contain a liquid carrier and in which the
outer tubular member is adapted to contain a dry material to be
taken up by the liquid carrier when the latter is forced from the
inner tubular member into the outer tubular member in response to
movement of the piston plug axially in the inner tubular
member.
4. A syringe as defined in claim 1 in which the piston ring portion
on the forward end of the inner tubular member comprises ring
members of rubber-like material in sealing engagement with the
outer walls of the inner tubular member and extending into sealing
engagement with the inner walls of the outer tubular member.
5. A syringe as defined in claim 1 wherein said disc member
includes a plurality of openings in a position offset outwardly
from axial alignment with the passage through the inner tubular
member.
6. A syringe as defined in claim 1 wherein the opening through the
disc portion is positioned in axial alignment with the passage
through the inner tubular member.
7. A syringe as defined in claim 1 which includes means on the
rearward end of the piston plug for attachment of an actuator and
which includes an elongate actuator dimensioned to exceed the
length of travel of the piston plug through the inner tubular
member.
8. A syringe as defined in claim 7 in which the actuator comprises
an elongate rod dimensioned to be received in telescoping relation
within the inner tubular member and with means for attachment of
the actuator to the piston plug.
9. A syringe as defined in claim 1 which includes flanged members
extending radially outwardly from the rearward end portions of the
inner and outer tubular members for use as finger grips.
10. A syringe as defined in claim 1 wherein said means supporting
said needle includes a bushing and a cap member secured to the
forward end of the outer tubular member and defining a recess, said
bushing being slidably positioned in said recess relative to the
cap member whereby insertion of the needle displaces the needle to
rupture said closure.
11. A syringe as defined in claim 1 wherein said means supporting
said needle includes a collapsible hub member secured to the
forward end of the outer tubular member, said hub member having a
flexible portion to permit displacement of the needle to penetrate
said closure in response to insertion of said needle.
Description
This invention relates to a device for the administration of
parenteral solutions and more particularly to a hypodermic syringe
adapted to contain dry solids separate and apart from the
dissolving or carrier liquids until, immediately prior to
administration, the liquid is caused to flow into the compartment
containing the solids for injection of the formed mixture.
To the present, it has been the practice to make use of stock
solutions housed within a container of relatively large capacity,
from which increments can be removed, as desired, for
administration by a suitable syringe. This procedure is deemed to
be unsatisfactory because most such solutions are of insufficient
stability to militate against change before the stock solution has
been used up. With a solution of short "shelf life", its utility
may become dissipated before the solution has been completely
utilized.
The most effective means for maintaining the "shelf life" over
extended periods of time is to maintain complete separation between
the liquid carrier and the solids to be incorporated therein, until
immediately prior to use. Maintenance of solid-liquid separation
until time of use presents other problems with respect to ejecting
and administering the solution containing the necessary
concentration of ingredients and under the most sanitary
conditions. The usual practice is to introduce the solids into the
liquid for solution in a suitable container from which the solution
can be withdrawn into a syringe for injection. This procedure
requires the use of at least three separate containers and
maintenance under sterile conditions as well as accurate
measurement of the ingredients.
In copending application Ser. No. 632,622, filed May 28, 1968 and
entitled "Disposable Syringe", description is made of a syringe in
which accurately measured amounts of solid medicants and liquid
carrier can be maintained in a completely separated state, and can
be admixed together and injected, while the contents of the syringe
are in a sealed and sanitary condition.
The present invention relates to a further improved syringe of the
type described in which use is made of a further simplified and
improved closure member between the liquid-containing and
solid-containing compartments.
It is an object of the present invention to provide a new and
improved syringe which houses both liquids and solids in separately
sealed compartments whereby admixture of the liquids and solids can
be effected completely within the confines of the syringe in a
simple and efficient manner to provide a freshly prepared medicant
solution which can be injected in the manner desired for use.
This and other objects and advantages of the invention will appear
hereinafter, and, for purposes of illustration, but not of
limitation, an embodiment of the invention is shown in the
accompanying drawings in which:
FIG. 1 is a sectional elevational view of a syringe embodying the
features of the invention, illustrating the position of the
elements prior to use;
FIG. 2 is a plane view of a flexible disc member forming part of
the closure assembly of the present invention;
FIG. 3 is a plane view of the flexible seal of the closure assembly
of the present invention;
FIG. 4 is a sectional elevational view of the syringe shown in FIG.
1 with the syringe partially actuated to effect displacement of the
liquid contents from the liquid-containing chamber to the
colids-containing chamber for admixture; and,
FIG. 5 is a sectional elevational view of the syringe shown in
FIGS. 1 and 2 with the syringe in fully actuated position to effect
displacement of the freshly prepared medicant solution from the
solids chamber for injection;
FIG. 6 is a sectional elevational view of an actuator which may
also be used as a needle cover;
FIG. 7 is a sectional elevational view of the syringe of FIG. 1
having an alternative needle assembly.
The concepts of the present invention reside in a syringe
comprising inner and outer tubular members with the inner tubular
member adapted to be telescoped within the outer tubular member, a
hypodermic needle assembly including a rupturable closure sealing
the forward end of the outer tubular member in which the closure is
adapted to be ruptured in response to displacement of a needle and
a flexible closure assembly sealing the forward end of the inner
tubular member including a disc member having one or more openings
therethrough communicating with the interior of the inner tubular
member and a flexible seal having a substantially flat surface
portion in face-to-face sealing contact with the disc member.
The surface portion of the flexible seal is also provided with at
least one opening therethrough, which is offset from the opening or
openings in the disc member to prevent the passage of a liquid
contained in a chamber defined by the inner tubular member. When
the interior of the inner tubular member is subjected to an
internal pressure during displacement of the liquid from the
chamber defined thereby, the liquid passes through the openings in
the disc to thereby flex the surface portion of the flexible seal,
forming a space between the flexible disc and the flexible seal.
Thus, the liquid contained in the chamber defined by the inner
tubular member can pass through the openings in the flexible disc
member and surface portion of the flexible seal, and through the
opening or openings in the flexible seal into the solids-containing
chamber defined by the outer tubular member for admixture with the
solids to form a fresh medicant solution for injection.
By the same token, an internal pressure in the chamber defined by
the outer tubular member, such as that caused during injection,
serves to urge the surface portion of the flexible seal toward
sealing contact with the disc to prevent flow of liquid through the
flexible closure assembly in the reverse direction. In this way
once admixture of the liquid with the solid has been made, it is no
longer necessary to maintain a pressure in the chamber defined by
the inner tubular member, and injection of the freshly prepared
solution can be effected by displacing the inner tubular member
toward the outer tubular member.
Referring now to the drawings, there is shown in FIG. 1 a syringe
embodying the features of the invention comprising an outer casing
10 in the shape of a tubular member formed of glass, plastic or the
like having a continuous bore 12 extending therethrough from an
open rearward end portion 14 of smaller cross section at the
forward end.
The forward end of tubular member 10 is sealed by means of a
diaphram or disc member 18 held in place in a sealing relationship
across the open neck 16 of tubular member 10 by means of a cap 20
forming part of the needle assembly which is crimped about the
outer neck portion of the tubular member, while the inner portions
22 of cap 20 overlap the outer edge of the disc member 18 overlying
annular flange 24 to tubular member 10. The rearward end of tubular
member 10 is formed with an outwardly extending flange 26 which
serves as a finger grip.
The needle assembly comprises the cap 20 which is crimped about
annular flange 24, and a hollow needle 28. Needle 28 is carried by
a bushing 30 which is slidably mounted in a recess 32 formed by the
annular wall 34 of cap 20, and is held in place by inwardly
extending flange 36 located on the annular wall 34 of cap 20.
Bushing 30 is provided at its rearward end with an outwardly
extending flange 38 having a cross section greater than the cross
section of flange 36 to prevent the bushing 30 and needle 28 from
being released from recess 32. In addition, bushing 30 and needle
28 are spring biased against flange 36 by spring means 40 to
maintain sharpened portion 42 of needle 28 which extends rearwardly
from bushing 30 adjacent to disc member 18.
A second tubular member 44 formed of glass, plastic or the like
material is dimensioned to have an outer wall-to-wall dimension
which is less than the inner wall-to-wall dimension of tubular
member 10 whereby the second tubular member 44 is adapted to be
telescoped through the outer tubular member 10. The second or inner
tubular member 44 is similarly formed with a passage 46 extending
from an open rearward end 48 through a neck portion 50 at the
forward end having a smaller cross section.
The forward neck end portion of the inner tubular member 44 is
fitted with flexible sealing member 52 including an outer ribbed
portion 54 fitted in a gripping relationship about the neck of
inner tubular member 44 and extending laterally beyond the wall of
the inner tubular member 44 for a distance to effect sealing
engagement with the inner wall of outer tubular member 10 whereby
inner tubular member is capable of functioning as a piston which is
moveable axially relative to the outer tubular member 10 to thereby
provide a piston and cylinder arrangement between the inner and
outer tubular members 44 and 10, respectively.
Flexible sealing member 52 is illustrated as having a gripping
member 56 which extends inwardly to grip annular flange 58 formed
at forward end of inner tubular member 44 to effect the gripping
relation described above. Flexible sealing member 52 is also
provided with a substantial flat or disc portion 60 having one or
more passage means 62 extending therethrough.
Disc portion 60 of flexible sealing member 52 overlays a disc
member 64 which in turn overlays annular flange 58 formed at the
forward end of inner tubular member 44. Thus, disc member 64 is
held in place in abutting relation with flange 58 by means of
flexible sealing member 52. Disc member 64, which need not be, but
preferably is formed of a flexible material such as rubber, is
provided with a plurality of openings 66 therethrough which
communicate with the chamber defined by tubular member 44, but
which are offset laterally from the opening or openings 62 defined
by the disc portion 60. Thus, when there is no internal pressure in
the chamber defined by tubular member 44, the openings 66 in disc
member 64 are sealed by the disc portion 60 of flexible sealing
member 52.
The disc member 64 and flexible sealing member 52 are best
illustrated in FIGS. 2 and 3, respectively. As shown in FIG. 2, the
openings 66 extending through disc member 64 are spaced about the
center of the disc member 64 but are spaced outwardly from axial
alignment with passage 46. As shown in FIG. 3, the opening 62 in
disc portion 60 is located at the center thereof. Disc member 64
and disc portion 60 are concentric, and thus opening 62 in disc
portion 60 overlays the center of disc member 64 in sealing
relation therewith. Thus, disc portion 60 of flexible sealing
member 52 is flexed for displacement from sealing relation with
disc member 64 in response to an internal pressure within the
chamber defined by tubular member 44. However, as will be
understood by those skilled in the art, openings 62 and 66 can have
a variety of other offset positions.
The rearward end portion of the inner tubular member 44 is formed
with an outwardly extending flanged portion 68 which similarly
serves as a finger grip, as will be hereinafter described. The
rearward end of passage 46 is sealed with an elastomeric plug 70
mounted for axial displacement through passage 46 as a piston
within the cylinder defined by inner tubular member 44. Means, such
as a threaded stud 72, is provided on the rearward end of the plug
70 for connection of an actuator 74 for displacement of the piston
70 relative to the cylinder.
In the drawing, the actuator 74 is in the form of a third elongate
tubular member dimensioned to have a cross section less than the
cross section of passage 46 through inner tubular member 44 and
formed at one end with an internally threaded engagement onto
threaded stud 72. The rearward end of actuator 74 is formed with an
outwardly extending flange portion 78 for use as a finger grip.
In the modification shown in FIG. 6, actuator 74' is capable of use
as a needle cover to protect needle 28 when not in a position ready
for use, and which can be removed from the bushing 30 to expose the
needle and for attachment to the stud 72 for operation of the
device, when in position for use. Thus, this element serves a dual
function of a needle protector during non-use and of an actuator in
use.
By way of further modification, use can also be made of a needle
assembly of the type described in copending application Ser. No.
732,622 as shown in FIG. 7 of the drawings. As illustrated in this
figure, the outer tubular member 10' is sealed at neck 16' by means
of a diaphragm 18' overlaying flange 24'. Diaphragm 18' is
maintained in a sealing position with flange 24' by means of a cap
78 which is crimped about the outer neck portion of tubular member
10' while the inner portion 80 of the cap 78 overlays diaphragm
18'.
A hub member 82 has a skirt portion 84 which is crimped about the
skirt portion of the cap for securing the hub onto the neck end
portion of tubular member 10'. The hub is also formed with an
intermediate collapsible portion 86 extending forwardly in axial
alignment with the forward end of tubular member 10' with a hub 88
on the forward end through which a hollow needle 28' extends with a
sharpened end portion 42' of needle 28' projecting into the
interior of hub member 82 for a distance less than the spaced
relationship between the hub end 88 and the diaphragm 18', when in
position prior to use, to thereby position the rearward end 42' of
the needle 28' immediately in advance of the center of the
diaphragm 18'.
In the assembled device as illustrated in FIG. 1, a fluid 90 is
housed within the inner tubular member 44, while a solid medicant
92 is housed within tubular member 10. Both chambers are sealed,
and therefore the loaded device can be stored and/or shipped for
extended periods of time without deterioration of the contents and
without exposure of the contents to non-sanitary conditions.
In use, the device can be held with two fingers under flange 68 of
the inner tubular member 44, and the actuator 74 is pressed by the
thumb to effect displacement of the plug 70 through cylindrical
passage 46. This in turn subjects the liquid 90 to pressure. The
liquid passes through openings 66 in disc member 64 whereby the
pressure transfers to the resilient disc portion 60 of flexible
sealing member 52 to cause flexure in disc portion 60 to thereby
form a small space 94 defined between disc member 64 and flexed
disc portion 60. Thus, liquid contained within tubular member 44 is
caused to be displaced under pressure through openings 66 in disc
member 64, into space 94 and through disc portion 60 through
opening 62 into the outer tubular member 10 in which the liquid 90
is admixed with the solid 92. This intermediate position is
illustrated in FIG. 4 of the drawing. The liquid carries the
medicant into solution or suspension, with shaking when necessary,
to provide a freshly prepared fluid system ready for administration
by injection.
Administration of the freshly prepared fluid system can be made
without transferring the fluid from one device to another and
without exposure by inserting the needle 28 into the vessel or
tissue. Thus, the outer casing is grasped with one hand with the
needle fingers between the flange 26, and the needle is inserted.
In the embodiment shown in FIG. 1, removal of the needle cover
releases the spring biased needle and bushing and causes the
bushing 30 carrying needle 28 to be displaced rearwardly whereby
the rearward end 42 of needle 28 punctures the diaphragm 18 to
bring the end of the needle into the chamber defined by tubular
member 10 for direct communication with the freshly prepared fluid
system.
In the embodiment shown in FIG. 7, insertion of the needle 28'
compresses the hub member 86 to effect relative movement between
needle 78' and diaphragm 18' whereby the rearward end 42' of needle
28' ruptures diaphragm 18' for direct communication with the liquid
system.
Thereafter, the thumb is pressed down on the actuator which, at the
end of its travel in tubular member 44, causes displacement of the
inner tubular member for movement as a piston through the
cylindrical passage 12 to thereby forcibly displace the freshly
prepared liquid system from the interior of tubular member 10
through the needle and into the tissue, as shown in FIG. 5. Reverse
flow of the liquid system due to a fluid pressure within tubular
member 10 back through openings 62 and 66 is prevented by virtue of
the fact that fluid pressure within tubular member 10 urges disc
portion 60 toward a sealing relation with disc member 64.
Upon administration of the freshly prepared solution, the entire
device can be discarded.
It will be apparent from the foregoing that I have provided a
simple disposable syringe capable of operation with one hand in
which liquids and solids are maintained in separately sealed
chambers and mixed immediately prior to injection by a simple
operation of the device.
It will be understood that changes may be made in the details of
construction, arrangement and operation without departing from the
spirit of the invention, especially as defined in the following
claims.
* * * * *