U.S. patent number 3,640,283 [Application Number 05/015,704] was granted by the patent office on 1972-02-08 for disposable blood-warming container.
This patent grant is currently assigned to Baxter Laboratories, Inc.. Invention is credited to Surindar Kumar Bhatia, Charles Rogers Memhardt.
United States Patent |
3,640,283 |
Bhatia , et al. |
February 8, 1972 |
DISPOSABLE BLOOD-WARMING CONTAINER
Abstract
A container for adjusting the temperature of liquids such as
blood flowing therethrough, which comprises a plastic envelope,
heat sealed to define a tortuous fluid flow conduit therein. The
conduit has an inlet and an outlet communicating with the exterior
of the container. The outlet communicates with the interior of a
drip chamber, the end of the outlet being spaced from the walls of
the drip chamber to permit liquid passing from the outlet to fall a
short distance through space, to indicate the rate of liquid flow,
and to separate and entrap in the drip chamber any gas bubbles
present.
Inventors: |
Bhatia; Surindar Kumar
(Evanston, IL), Memhardt; Charles Rogers (Morton Grove,
IL) |
Assignee: |
Baxter Laboratories, Inc.
(Morton Grove, IL)
|
Family
ID: |
21773044 |
Appl.
No.: |
05/015,704 |
Filed: |
March 2, 1970 |
Current U.S.
Class: |
607/106;
165/46 |
Current CPC
Class: |
A61M
5/44 (20130101); A61M 1/3627 (20130101); A61M
1/369 (20130101); A61M 2205/3653 (20130101) |
Current International
Class: |
A61M
1/36 (20060101); A61M 5/44 (20060101); A61f
007/00 () |
Field of
Search: |
;128/214,214.2,254,258,399,402,403 ;165/46 ;23/258.5 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Truluck; Dalton L.
Claims
What is claimed is:
1. A container for adjusting the temperature of liquid flowing
therethrough, which comprises a plastic envelope, heat sealed to
define a tortuous fluid flow conduit therein, an inlet and an
outlet to said conduit communicating with the exterior of said
container, a drip chamber, said outlet communicating with the
interior of said drip chamber and disposed in transverse relation
to said drip chamber passing through a sidewall of said chamber,
the end of said outlet being spaced from the walls of said drip
chamber to separate and trap in said chamber any bubbles
present.
2. The container of claim 1 in which said inlet is spaced below
said outlet in position of use to facilitate the bubble-free
filling of said fluid flow conduit by said liquid flowing
therethrough.
3. The container of claim 2 in which said drip chamber has a liquid
exit port which communicates with flexible tubing having means for
mounting a blood administration needle thereon.
4. The container of claim 3 in which said inlet is in fluid
communication with flexible tubing having coupling means for
connection to a blood supply.
5. The container of claim 4 having a single tortuous fluid flow
conduit.
Description
BACKGROUND OF THE INVENTION
Between collection and administration, blood is generally kept in
refrigerated condition to prolong its useful life. However, when an
individual requires the administration of blood, the blood must be
warmed prior to administration in order to avoid placing excessive
stress upon the metabolism of the individual by administering cold
blood.
Conventional blood warmers such as disclosed in the Pins U.S. Pat.
No. 3,475,590 are used with a disposable plastic blood flow liner
within an electrically operated blood warming apparatus or the
like. However, difficulties have been encountered in that as the
blood is warmed, its capacity to retain dissolved gases is reduced,
and thus gas bubbles are formed which flow along with the blood out
of the warming apparatus. Also, bubbles are formed from entrapped
air as conventional blood flow liners are filled. It is extremely
important that these gas bubbles be removed prior to administration
of the warmed blood to the patient, and typically, the blood is
directly transferred from the blood warmer to the patient without
further storage.
It is also important to determine the rate of blood flow through
the blood warmer and the corresponding rate of blood administration
to the patient.
DESCRIPTION OF THE INVENTION
The invention of this application provides means for automatically
removing gas bubbles from the blood prior to administration, while
simultaneously providing a flow rate indicating means in
conjunction with a disposable liner which can be used with a
conventional blood warmer of, for example, the electrical type or
the warm water heat exchange type.
In accordance with this invention, a container or liner for
adjusting the temperature of liquids such as blood flowing
therethrough comprises a plastic envelope heat sealed to define a
tortuous fluid flow conduit therein. The conduit has an inlet and
an outlet communicating with the exterior of the container, the
outlet communicating with the interior of a drip chamber to permit
liquid passing from the outlet to fall a short distance through
space. By this, the rate of liquid flow from the blood container is
indicated and an opportunity is provided for gas bubbles to be
trapped in the drip chamber to prevent bubbles from being swept on
into the patient.
Typically, the inlet is spaced below the outlet in the position of
use and at one end of the container, while the outlet is spaced at
the other end to facilitate the bubble-free filling of the fluid
flow conduit by the liquid flowing therethrough. The displaced air
in the conduit is swept through the chamber in front of the
advancing liquid and out of the exit port, until the system is
filled and ready for administration to the patient.
Referring to the drawing, a preferred embodiment of this invention
is shown in plan view.
A pair of plastic sheets 10, 12, made of vinyl or the like, are
shown laid together in side by side relationship and secured
together by sets of heat seals 14, 16 to define a tortuous fluid
flow conduit 17 passing through the container. A plurality of
tortuous conduits in parallel relation can also be used, if
desired. The container has an inlet tube 18 and an outlet tube 20
leading into respective ends of the tortuous fluid flow conduit,
both the inlet and the outlet communicating with the exterior of
the container.
Outlet 20 communicates with the interior of a drip chamber 22,
which is typically made of plastic tubing, heat sealed at both
ends. Outlet 20 is disposed in a transverse relation to the drip
chamber 22, passing through tubular outer jacket 21, and sidewall
24 of chamber 22, to prevent kinking of outlet 20. An advantage to
this construction is that when the container is oriented in its
position of use with heat sealed end 26 of drip chamber 22 pointing
downward, the fluid flowing through last horizontal leg 28 of the
tortuous fluid flow conduit tends to separate any remaining gas
bubbles entrapped in the conduit or generated by heating of the
liquid upwardly to the top of leg 28 and outlet 20. Then, when the
liquid and separated gas bubbles come to the end 30 of conduit 20,
the liquid falls downwardly and tends to be further separated from
the gas bubbles, which join the entrapped gas portion of the drip
chamber.
Typically, for the administration of one unit of blood, only a 15
to 20 cc. drip chamber needs to be used since approximately 1 or 2
cc. of gas are generated during the heating process, and there are
only very few, if any, bubbles of air trapped in the system during
filling because of the advantageous configuration described
above.
The drip chamber 22 is supported by brace 32, which is attached to
both the drip chamber and plastic sheets 10 and 12. A liquid exit
port 34 is located in heat sealed end 26 of the drip chamber, and
typically carries or communicates with flexible tubing 36, which
has conventional means 38 for mounting a blood administration
needle thereon for administration of blood to the patient. In the
embodiment shown, mounting means 38 has a sterile covering 40, a
latex supplemental injection site 42, and a roller clamp 44 for
adjusting flow through tubing 36.
Inlet 18 communicates with flexible tubing 46, which in turn
connects to coupling means 48 for connection to a blood supply,
such as a blood bottle or bag. Coupling means 48 is closed with
sterile seal means 50.
The container of this invention can be used in a blood warmer of
the type disclosed in the above-cited Pins patent by sliding sealed
sheets 10 and 12 into the slot of the blood warming device
described therein, or it can be utilized in other types of blood
warmers, such as those comprising a pair of opposed warming plates
hinged to each other to swing open and closed, and having studs for
mounting the container of this invention on one of the heating
plates. In the embodiment shown, tabs are provided defining holes
52 for emplacement of the container on such studs for proper
positioning in such a blood warmer. The holes 52 and studs of such
a blood warmer are arranged in an asymmetrical manner to prevent
the container from being inserted in improper orientation.
The above description is intended for illustrative purposes only,
and it is seen that many modifications of this invention can be
readily made which fall within the teachings of this invention.
* * * * *