U.S. patent number 3,635,223 [Application Number 04/881,363] was granted by the patent office on 1972-01-18 for embolectomy catheter.
This patent grant is currently assigned to United States Catheter & Instrument Corporation. Invention is credited to Charles H. Klieman.
United States Patent |
3,635,223 |
Klieman |
January 18, 1972 |
EMBOLECTOMY CATHETER
Abstract
Apparatus for extracting emboli comprising a cannula, preferably
guidable, adapted to be projected through a body passage (e.g.,
vein or artery) to a point adjacent the embolus to be removed,
together with a catheter adapted to be passed through the cannula
and having a distal end provided with an inflatable balloon the
surface of which has rearwardly angled protrusions designed to
engage an embolus into which the catheter end has been projected
and to convey the captured embolus into the cannula as the catheter
is withdrawn therein.
Inventors: |
Klieman; Charles H. (Brooklyn,
NY) |
Assignee: |
United States Catheter &
Instrument Corporation (Glens Falls, NY)
|
Family
ID: |
25378330 |
Appl.
No.: |
04/881,363 |
Filed: |
December 2, 1969 |
Current U.S.
Class: |
606/194; 606/200;
606/192; 604/916 |
Current CPC
Class: |
A61M
25/1002 (20130101); A61B 17/22 (20130101); A61B
90/39 (20160201) |
Current International
Class: |
A61B
17/22 (20060101); A61M 25/10 (20060101); A61B
19/00 (20060101); A61m 025/00 (); A61b
017/22 () |
Field of
Search: |
;128/348-351,344,303,325,246,DIG.9,2,356,328 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Truluck; Dalton L.
Claims
What is claimed is:
1. An embolectomy catheter comprising an elongated tubular body
having a closed soft flexible distal tip, at least one perforation
through the wall of said tubular body adjacent said tip, inflatable
sleeve of elastomeric material covering said perforation and sealed
to the surface of said body distally and proximally of said
perforation, and a plurality of protrusions of the same material
integrally formed on said sleeve at a plurality of circumferential
points, projecting laterally therefrom and slanted away from said
distal tip, whereby when said tip is inserted within a blood vessel
past an embolus, said slanted protrusions will engage said embolus
and upon retraction of said catheter will ensure withdrawal of said
embolus from the blood vessel.
2. A catheter according to claim 1 which includes a fitting on the
proximal end of said body adapted to receive a syringe tip.
3. A catheter according to claim 1 in which the catheter is of a
woven plastic material having dimensional stability and being at
least partially radiopaque.
4. A catheter according to claim 1, in which the sleeve is sealed
to the body by a circumferential tie covered by adhesive.
5. In combination, a catheter according to claim 1 and an outer
cannula having at least one lumen open at both ends, the diameter
of said lumen being substantially as great as the diameter of a
circle passing through the outer ends of said protrusions, the
length of said cannula being less than the length of the catheter,
and said catheter being slidably received within in said
cannula.
6. The combination of claim 5 in which the distal end of the
cannula has a slanted opening, the area of which is larger than the
cross-sectional area of the cannula lumen.
7. The combination of claim 5 in which the cannula is a radiopaque
vinyl plastic and the catheter is at least partially radiopaque.
Description
BACKGROUND OF THE INVENTION
A definite need exists for a catheter unit to remove pulmonary
emboli. A pulmonary embolus is a blood clot that has formed in some
area of the body and traveled via the venous system into the
pulmonary arteries. The site of origin of these emboli is usually
the veins of the leg, secondary to conditions such as
thrombophlebitis. If a massive pulmonary embolus occurs, the
mortality rate is high. The only method available at this time to
remove these clots is by a direct surgical attack on the pulmonary
artery. Even then the mortality rate is very high. The present
catheter unit's purpose is to avoid the need for surgery and permit
the emboli to be removed via a peripheral vein such as the femoral
vein. Other uses have been developed for one or both parts of the
catheter unit to be described. Each use will be described in
detail.
A practical embodiment of the invention is shown in the
accompanying drawing wherein:
FIG. 1 represents an elevation of the outer guided cannula with the
extraction catheter inserted therethrough, parts being broken
away;
FIG. 2 represents a cross section on the line II--II of FIG. 1;
FIG. 3 represents an elevation of the distal tip of the extraction
catheter on an enlarged scale;
FIG. 4 represents an end view of the tip shown in FIG. 3;
FIG. 5 represents detailed axial sections of the catheter, adjacent
its distal tip, and of the balloon prior to assembly thereof;
FIG. 6 represents the same parts as in FIG. 5, assembled; and
FIG. 7 represents an elevation of a mandrel on which the balloon
may conveniently be formed.
Referring to the drawings, the apparatus is shown as comprising two
parts, the outer guided cannula 10 and the inner catheter 11,
constituting the emboli-extracting instrument.
The outer cannula 10, which may be 80 cm. to 100 cm. in length, is
preferably 20 F. in diameter with a substantially circular lumen
having a diameter on the order of 0.164 inch, its distal end 12
being opened at an angle to provide an actual opening larger than
the lumen. The cannula 10 is formed with a main lumen 16 and a
small second lumen 13, open at the distal end (e.g., in the short
end of the bevel) and provided at its tubular proximal end 14 with
a fitting 15, to receive a syringe tip for the injection of dye,
for instance. The cannula 10 is flared proximally, as indicated at
28, to permit insertion of the catheter 11, as described below; it
is also provided with a deflecting device comprising the operating
handle 17 and a fine wire 18 secured at its distal end 19 near the
distal end 12 of the cannula, by which means said cannula end can
be deflected, in a known manner, and guided to desired locations.
The handle 17 may be of the type shown in Muller U.S. Pat. No.
3,425,740, or an adaptation thereof. The material of the cannula 10
is suitably a radiopaque polyvinyl chloride or equivalent
nonreactive, nontoxic and atraumatic material, with or without wire
reinforcement.
The inner catheter 11, 20 cm. to 25 cm. longer than the cannula 10
may be 3 F. to 8 F. in diameter, radiopaque and of woven Dacron or
the like. Its distal tip 20 is soft, flexible and closed, and its
proximal end 21 is provided with a fitting 22 to receive tip of a
syringe for a purpose described below. The catheter 11 has an
inflatable balloon 23 of latex, vinyl or other suitable elastomeric
material mounted adjacent its distal tip, the balloon being
constituted by a substantially cylindrical sleeve long enough to
cover the openings 24 normally provided near the tip of such a
catheter, the ends of the sleeve being tied by threads 25 and
tightly secured to the surface of the catheter by said threads and
by an application of a suitable adhesive 26 over the threads and
adjacent edges of the sleeve.
The balloon is provided with a plurality of integrally formed
"barbs" or protrusions 27, each approximately 1 mm. in length,
slanted away from the tip of the catheter at angles of 30.degree.
to 60.degree., for instance (45.degree. being shown), and
distributed around the balloon surface at intervals preferably no
greater than 90.degree. with respect to the catheter axis. The
diameter of the balloon portion, including protrusions 27, should
be not appreciably greater than the inside diameter of the cannula
(e.g., less than 0.164 inch) with the balloon collapsed (not
inflated), to enable said portion to be passed through the cannula,
as described below, without undue frictional resistance.
In using the apparatus for pulmonary embolectomy, the
emboli-extracting catheter 11 is placed within the outer cannula
10, the unit is introduced into the femoral vein, and under
observation with an image intensifier, is guided up through the
vena cava, through the right side of the heart and out into the
pulmonary artery. Dye is then injected to determine the exact
location of the embolus, so that the distal end of the cannula 10
may be placed close to it. The inner catheter 11 is pushed through
and past the clot, (e.g., to a position as shown in FIG. 1 with
respect to the cannula 10) and then pulled back, the protrusions 27
engaging the clot and ensuring its capture and withdrawal into the
cannula through the enlarged opening in the end 12. If necessary,
due to the size of the vein and/or clot, the balloon 23 may be
inflated by means of a syringe engaged in the fitting 22, the vinyl
balloon having sufficient elasticity to permit an appreciable
increase in its effective diameter. Following the first withdrawal
of the catheter into the cannula, dye is again injected to
determine if all the clot has been removed, and repeated
projections and retractions of the catheter can be made until the
clot removal is completed. The slanting arrangement of the
protrusions 27 ensures that they will engage the clot only for
withdrawal, emerging from the cannula relatively "clean" for each
repeated pass, if more than one pass is needed. When the clot
appears to have been completely captured, the entire unit is
removed.
It has been found that, in many instances, the presently used
Fogarty catheter is not fully effective to remove iliofemoral
venous or arterial emboli. The inner emboli-extracting catheter 11
can be used (without the cannula 10) for this purpose. Its
advantages reside in the soft flexible tip, the vinyl balloon with
slanted protrusions, and its ability to remove clots without
necessarily having to inflate the balloon in the vessel. In such an
operation the catheter is introduced distally into the femoral
artery or vein and advanced past the embolus, the soft flexible tip
ensuring that the vessel wall will not be damaged. After the
balloon has been pushed past the clot, it is withdrawn, the
protrusions 27 engaging the clot and removing it. If necessary, the
balloon may be inflated to the desired extent to ensure engagement
with and removal of the clot. Repeated passes may be made into the
femoral, deep femoral, popliteal and iliac vessels to completely
remove the clot or clots. The protrusions on the balloon are
rounded and sufficiently flexible to avoid damage to the vessel but
are firm enough to hold onto the clot. When using the catheter 11
without the cannula 10 it is particularly convenient and desirable
for the catheter to be calibrated at suitable intervals such as
every 10 cm.
Instances have been reported of occlusion of the renal artery by
emboli, and the only presently known procedure for saving the
affected kidney is operating on the patient to remove the clot. The
cannula and catheter described herein can be used to remove such
clots, thus avoiding the need for surgery. In this situation, the
assembled unit is passed up the femoral artery to the level of the
renal artery, as located by the injection of dye. The slant-opened
distal tip 21 of the cannula is approximated to the opening of the
renal artery and the inner catheter 11 is then projected into the
renal artery to pass, engage and remove the clot or clots as
described above. The clot or clots captured with the cannula are
then removed as the cannula is withdrawn.
A convenient and economical means for making the balloon 23 is
illustrated in FIG. 7, where the metal (e.g., brass) mandrel 30 is
shown as having a handle 31, a shank 32 and a cylindrical enlarged
portion 33 tapering smoothly at both ends to the diameter of the
handle, as indicated at 34. A plurality of slanting tapering holes
35 are drilled at suitable points, corresponding to the desired
number and distribution of the projections 27. The mandrel is used
by dipping in a bath of elastomeric material, maintained
sufficiently liquid to flow into the holes 35, the material
depositing on the mandrel to the desired thickness. After removal
from the bath, the deposited material is cured in an appropriate
manner, the sleeve with "barbs" on its inner surface is turned
inside out, and the ends trimmed to leave a balloon as shown at the
right of FIG. 5. The inside diameter of the cylindrical portion of
the balloon may conveniently be slightly greater than the outside
diameter of the catheter, as indicated in FIG. 6, the actual
difference being on the order of 0.010 to 0.020 inch.
As used herein, "distal" refers to the leading end or direction of
advancement into the body and "proximal" refers to the end or
direction opposite to said distal end or direction.
* * * * *