U.S. patent number 3,625,208 [Application Number 04/825,528] was granted by the patent office on 1971-12-07 for apparatus for pressure-administering medicaments.
This patent grant is currently assigned to Mediquip Corporation. Invention is credited to Philip Frost, Harry Van Der Gaast.
United States Patent |
3,625,208 |
Frost , et al. |
December 7, 1971 |
APPARATUS FOR PRESSURE-ADMINISTERING MEDICAMENTS
Abstract
Apparatus for pressure administration of a fluent medicament in
which a medicament-containing cartridge includes a needlelike
outlet bore communicating with a chamber containing the medicament
and includes a dispensing piston exposed at the rear end of the
cartridge, and the cartridge is removably mounted on the barrel of
a dispensing apparatus which includes a handle and actuator, in
which the actuator controls a force transmitting assembly having a
force transmitting rod directed toward the piston of the medicament
cartridge and in which the force transmitting rod is subject to a
buildup of axial pressure normally urging the rod toward the
dispensing piston during an initial increment of travel and
subsequently forcibly engages the piston during a terminal portion
of the travel causing the medicament to be forcibly discharged at a
skin-penetrating pressure from the needlelike outlet of the
cartridge, and means for resetting the apparatus for subsequent use
with another cartridge.
Inventors: |
Frost; Philip (Miami Beach,
FL), Van Der Gaast; Harry (Miami Beach, FL) |
Assignee: |
Mediquip Corporation
(N/A)
|
Family
ID: |
25244230 |
Appl.
No.: |
04/825,528 |
Filed: |
May 19, 1969 |
Current U.S.
Class: |
604/68;
604/223 |
Current CPC
Class: |
A61M
5/30 (20130101) |
Current International
Class: |
A61M
5/30 (20060101); A61m 011/00 () |
Field of
Search: |
;128/173,173H,173.1,218,218R |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Reich; Joseph S.
Claims
What is claimed is:
1. Apparatus for pressure-administering fluent medicament
comprising, in combination:
a body member,
said body member including handle means angularly extending from
one end and barrel means,
said barrel means opening away from said handle means;
force-transmitting means in said barrel means, said
force-transmitting means including an actuator portion,
power-storing-and-power-release means operatively connected to an
operator portion; and
means on said barrel means for detachably mounting a medicament
cartridge assembly on said barrel means for operating engagement by
said operator portion of said force-transmitting means, said
force-transmitting means comprising a rod element supported for
rectilinear movement in said barrel means, spring means normally
urging said rod element toward said handle means,
an actuator bracket reciprocably supported on said rod for relative
movement with respect to said rod, at least one leaf spring
disposed along the path of movement of said actuator bracket and
converging toward said rod and bracket element, said leaf spring
including an abutment extending toward said rod and an abutment
surface extending generally toward the path of movement of said
rod, an abutment-and-camming element on said rod and abuttingly
engageable with said leaf spring abutment and including an upwardly
converging camming surface extending toward said rod,
a power spring interposed between said abutment-and-camming element
on said rod and said bracket element whereby initial relative
movement of said actuator bracket element with respect to said rod
causes said power spring to be compressed and forces said rod
toward the abutment element on said leaf spring, and subsequent
movement of said actuator bracket element with respect to said rod
causes said power spring to be compressed and forces said rod
toward the abutment element on said leaf spring, and subsequent
movement of said actuator bracket laterally displaces the leaf
spring and permits the rod to forcibly move toward the open end of
said barrel means, and a return stroke causes said leaf spring to
be biased outwardly due to engagement with the camming surface of
said rod.
2. Apparatus for pressure-administering fluent medicament
comprising, in combination:
a body member,
said body member including handle means angularly extending from
one end and barrel means,
said barrel means opening away from said handle means;
force-transmitting means in said barrel means, said force
transmitting means including an actuator portion,
power-storing-and-power-release means operatively connected to an
operator portion;
means on said barrel means for detachably mounting a medicament
cartridge assembly on said barrel means for operating engagement by
said operator portion of said force-transmitting means,
said force-transmitting means comprising an elongated rod,
a cam-and-abutment element on an intermediate portion of said
rod,
an actuator bracket element connected to said operator portion and
reciprocably mounted on said rod, compression spring means
interposed between said bracket element and said cam-and-adjustment
element whereby movement of said bracket element toward the
cam-and-abutment element urges the rod away from said bracket
element,
laterally displaceable, resiliently supported abutment means
interposed in the path of travel of said cam-and-abutment means and
displaceable by said bracket element after a previously determined
amount of travel and corresponding compression of said compression
spring whereby said compression spring forcibly urges said rod
toward the open end of the barrel means.
3. The structure as claimed in claim 1 in which said
cam-and-abutment element includes at least one upwardly converging
cam surface for laterally displacing said resiliently supported
abutment means for recocking the force transmitting means.
4. The structure as claimed in claim 1 in which said resilient
supported abutment means comprises at least one leaf spring
extending longitudinally within said barrel means and secured at
one end to an intermediate portion of said barrel means and
including a forward end converging toward the path of reciprocation
of said rod.
Description
The administration of various antibiotics, serums etc. has
generally been accomplished through the use of a hypodermic
syringe, and needle or cannula. The average person, and children in
particular, demonstrate a tremendous resistance to having
innoculations or "shots" because of their fear of the penetrating
needle of the hypodermic syringe. It has been found that certain
medicaments e.g. vaccines, antitoxins, corticosteroids, insulin,
etc. are of the character which can be introduced between the skin
layers.
Primary objects of the present invention are:
To provide novel apparatus for pressure-administering
medicaments;
To provide novel apparatus for pressure-administering medicaments
from a disposable cartridge;
To provide a novel pressure-administering apparatus in combination
with a novel disposable dose cartridge;
To provide novel apparatus for administering medicaments in which
the apparatus includes force-transmitting means contained in a
barrel having means for connection to a disposable dosage cartridge
in which the force-transmitting means includes the
force-transmitting rod operatively connected to an actuator and
includes, during an initial increment of travel, means for imposing
or storing a residual axial force acting against the rod and urging
it toward a removable cartridge, and during a subsequent or
terminal portion of travel the stored up energy or force is
suddenly released whereby the rod is forcibly exerted at the dosage
cartridge and acts on a dispensing piston communicating with a
chamber containing the dose of medicament being administered, and
in which said chamber communicates with a minute needlelike bore
whereby the medicament is pressure injected beneath the surface of
one's skin.
These together with other and more specific objects and advantages
will become apparent from a consideration of an exemplary
embodiment of the invention when taken in conjunction with the
drawing forming a part thereof, in which:
IN THE DRAWING
FIG. 1 is a vertical section showing the novel apparatus, and
showing by means of phantom lines an alternate position of the
parts during use;
FIG. 2 is a horizontal section taken substantially on the plane of
line 2--2 of FIG. 1;
FIG. 3 is a section taken substantially on the plane of line 3--3
of FIG. 1; and
FIG. 4 is a fragmentary view, similar to a portion of FIG. 1, and
showing the position of the parts immediately after the medicament
has been administered.
Referring to FIG. 1, apparatus for pressure-administering a
medicament is indicated generally at 10 and comprises an applicator
device 12 and removable dosage cartridge 14. The applicator device
12 includes a barrel 16 (preferably cylindrical) integral with a
rear angularly extending handle 18. The barrel 16 is slotted at 20
i.e. adjacent to handle 18 and accommodates for pivotal movement on
a transverse pivot pin 22 an actuator lever 24. Mounted on a
transverse support pin 26 at the upper portion of the handle 18 is
a hairpin spring 28 (or its equivalent) including legs 30 and 32
respectively engaging the handle 18 and actuator 24 to urge the
same apart.
Pivotally connected to the upper end of the actuator 24 by means of
pivot pin elements 34 and 36; see FIG. 2, are apertured, connecting
ear portions 38 and 40, respectively, extending rearwardly from a
substantially U-shaped, vertically extending actuating bracket
element indicated generally at 42. The actuator bracket 42 includes
slightly diverging legs 44 and 46 connected by an upper rear wall
48 which is integral with the apertured ear portion 38 and 40;
previously mentioned. The legs 44 and 46 include lower, transverse
sleeve portions 50 and 52, respectively; see FIG. 3, connected or
restrained against relative movement by means of a C-shaped clip 54
which has upper and lower pin portions received in the sleeves and
a horizontal portion flanking one side of the legs 44 and 46.
The wall 48 of the actuator bracket is centrally apertured at 56;
see FIG. 2 and an elongated force-transmitting rod 58 has fixed on
an intermediate portion thereof an abutment washer 60 and projects
rearwardly from the wall 48 and forwardly between the legs 44 and
46 of the actuator bracket and through an apertured support element
62, terminating in a forward, rounded distal end 64. The rod 58 has
secured rearwardly of the distal end 64 in space relation from the
abutment washer 60 an abutment-and-camming element 66 which
includes side upwardly converging camming surfaces 68 and 70
respectively, and lower abutment surfaces 72 and 74, respectively.
Circumposed about the rod 58 between the rear surface of the
camming-and-abutment element 66 and the opposed surface of the rear
wall 48 of the actuating bracket 42 is a compression spring 76
which serves the purpose of storing axially imposed energy during
an initial portion pivotal movement of the actuator lever 24, and
subsequently forcibly releasing and urging the actuating rod 58
axially downwardly, see FIG. 1, during operation of the device.
Extending downwardly along opposed upper and lower portions of the
barrel 16 and secured at 78 and 80 are inwardly directed leaf
spring elements 82 and 84, respectively, which include on their
opposed respective inner surfaces abutment elements 86 and 88
having a rear abutment surface 90 and 92 respectively, and forward
diverging camming surfaces 94 and 96, respectively.
The cartridge 14 includes a nozzle portion produced from any
suitable material i.e. preferably a molded plastic and includes a
forward, relatively minute needlelike dispensing bore 100 in direct
communication with a rearwardly opening chamber 102. The rear
portion of the nozzle 104, is suitably connected by means of a
relatively coarse thread, bayonet-and-slot connection etc. to the
lower open end of the barrel 16. Contained in the chamber 102 is a
dosage cartridge 106 open at its forward end 108 and containing
therein a charge of fluent medicament 110. The medicament 110 is
restrained at the rear in the dosage cartridge 106 by a suitably,
peripherally sealed dispensing piston 112 including a rear
actuating stem 114 engageable by the terminal rounded end of rod
end 64 of the rod 58 as will presently be described, and
atmospheric pressure retains the medicament from passing through
bore 100 until piston pressure is applied.
Referring to FIG. 1, the cartridge 14 is mounted on the forward
open end of the barrel 16 of the dispensing device. The parts are
in the solid line position shown, and the handle 18 and actuating
lever 24 are grasped in one's hand. The needlelike bore 100 is
placed on that portion of the anatomy where the medicament 110 is
to be administered, and is held thereat at a sufficient sealing
pressure. The actuating lever 24 is pivoted about pin 22 to the
phantom line position as illustrated. This pivotal movement results
in the actuating bracket 42 moving toward the left and accordingly
compressing spring 76 as indicated. During the leftward movement of
the spring 76, and its compression due to leftward movement of the
actuating bracket 42, the forward ends of the actuating bracket
i.e. the sleeves 50 and 52 will tend to urge the leaf springs 82
and 84 apart toward the position shown by phantom lines in FIG. 1.
The abutment elements 86 and 88 will restrain leftward movement of
the actuating rod 58 and prevent the terminal end 64 thereof from
engaging the stem 114 of dispensing piston 112. However, the rear
surfaces 90 and 92 of the abutment elements 86 and 88 respectively,
will eventually be moved laterally out of the path of movement of
the camming-and-abutment element 66. When this occurs, the energy
stored in the compression spring 76 forcibly urges the rod 58
toward the left wherein the rounded end 64 forcibly engages the
stem 114 and causes the piston 112 to move downwardly as
illustrated in FIG. 4. The diameter of the piston 112, in this
exemplary embodiment is illustrated as being approximately 10 times
the cross-sectional area of the needlelike bore 100. Thus if 20
pounds per square inch of pressure is generated by the piston 112
as it is forcibly urged downwardly in FIG. 4, for example,
approximately ten times or 200 pounds per square inch of pressure
would be exerted by the medicament discharged from the needlelike
bore 100. The forward end of the nozzle 104 will generally be
covered by a sterile cover element and the medicament 110 will not
move out of the needlelike bore 100 due to atmospheric
pressure.
The medicament will have been administered when the parts are in
the position shown in FIG. 4, at which time the compression spring
76 reassumes its noncompressed condition. The abutment-and-camming
element 66, it will be noted, is disposed below the elements 86 and
88 at the ends of the respective leaf springs 82 and 84. The hair
pin spring 28, when the lever 24 is no longer clamped in one's
hand, tends to urge the lever 24 back to the solid line position
shown in FIG. 1, and when this occurs, the actuator bracket rear
wall 48 engages the abutment washer 60 drawing the rod 58 upwardly
and the camming surfaces 68 and 70 respectively urge the leaf
spring elements 82 and 84 apart so that the abutment element 66 can
once more assume its position above the elements 86 and 88, i.e.
the solid line position of FIG. 1.
Thereafter, the cartridge 14 can be removed and replaced by another
sterile cartridge having another dose of the medicament to be
administered.
* * * * *