U.S. patent number 3,623,474 [Application Number 04/567,643] was granted by the patent office on 1971-11-30 for angiographic injection equipment.
This patent grant is currently assigned to Medrad, Incorporated. Invention is credited to Marlin S. Heilman, Donald Jones.
United States Patent |
3,623,474 |
Heilman , et al. |
November 30, 1971 |
ANGIOGRAPHIC INJECTION EQUIPMENT
Abstract
An angiographic injector system for producing a controlled rate
of flow of injection fluid is described. The injector has a
motor-driven piston for ejecting fluid from a syringe cartridge
contained within a pressure jacket. The drive motor is operated in
accordance with a command voltage which is proportional to the
desired rate of flow. Sensing means detects the actual rate of flow
and comparison means provides an error signal which controls the
motor. Compensating means allow a single control system to operate
the drive motor in conjunction with syringes of various sizes, and
a tripping circuit halts the motor if the flow rate exceeds the
selected rate.
Inventors: |
Heilman; Marlin S. (Gibsonia,
PA), Jones; Donald (Pittsburgh, PA) |
Assignee: |
Medrad, Incorporated
(Pittsburgh, PA)
|
Family
ID: |
24268034 |
Appl.
No.: |
04/567,643 |
Filed: |
July 25, 1966 |
Current U.S.
Class: |
600/432; 604/67;
604/155 |
Current CPC
Class: |
A61B
6/504 (20130101); A61M 5/14546 (20130101); A61B
6/481 (20130101); A61M 5/14566 (20130101); A61M
2005/14553 (20130101) |
Current International
Class: |
A61B
6/00 (20060101); A61M 5/145 (20060101); A61b
006/00 (); A61m 005/20 () |
Field of
Search: |
;128/2,2.05,218,218A,215
;137/30,36 ;318/345,347,309-312,318,349,350 ;222/55,63,76
;103/11,12,35,36 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Truluck; Dalton L.
Claims
I claim:
1. In an injector system for producing a controlled rate of flow of
injection fluid for use in angiography and having an injector
including syringe means for said fluid, movable piston means for
ejecting said fluid from said syringe means, a drive motor for
moving said piston, electrical control means including command
means for producing a command signal which is a function of a
desired rate of fluid flow, sensing means for producing a second
signal which is a function of the actual injection flow of said
fluid, and means for comparing said command and second signals to
produce a resultant signal for operating said drive motor at a
selectable, controlled rate to produce a desired flow of fluid
whereby the rate of flow of said injection fluid will be
substantially independent of flow-attenuating factors in the path
of said fluid, the improvement comprising electrical circuit means
responsive to said control means for stopping said drive motor and
thereby automatically terminating the flow of said fluid upon the
occurrence of a condition within said system that could result in
an excessive rate of flow of said fluid.
2. The system of claim 1, wherein said circuit means is responsive
to an overrate condition, said circuit comprising means for
producing a threshold signal in response to said overrate condition
and gating means responsive to said threshold signal for thereupon
disabling said drive motor.
3. The system of claim 2, wherein said means for producing a
threshold signal comprises potentiometer means connected to said
command means and to said sensing means.
4. The system of claim 3, wherein said potentiometer means
comprises a nonlinear resistor having a first movable arm, said
first arm being electrically connected to said gating means, said
command means including a linear potentiometer having a second
movable arm, said first and second movable arms being mechanically
interconnected.
5. The injector system of claim 4, wherein said circuit means
further includes normally closed relay means for controlling said
drive motor, and silicon controlled rectifier means in series with
said relay means, said rectifier means being connected to and
responsive to the operation of said gating means to open said
normally closed relay means to deenergize said drive motor.
6. The injector system of claim 1, wherein said control means is
mounted in a control cabinet separate from said injector, said
control means being connected to said injector through flexible
electrical conductor means, said injector being sufficiently small
and compact to facilitate use as a hand-held unit.
7. The injector system of claim 6, wherein the drive motor for said
injector is a direct current, permanent magnet, torque-type motor
having a printed circuit armature to provide a small, lightweight,
compact injector.
8. The injector system of claim 1, the improvement further
comprising signal generator means responsive to the operation of
said motor for producing said second signal, and scale factor means
for maintaining said second signal proportional to the injection
flow of said fluid for various cross sections of said syringe
means, whereby said system can be used with a variety of
syringes.
9. The injector system of claim 8, wherein said scale factor means
comprises selectively variable voltage divider means.
10. The injector system of claim 1, the improvement further
comprising signal generator means on said injector responsive to
the operation of said motor for producing said second signal, and
said control means further including generator compensating means
connected to said generator for maintaining said second signal
proportional to the injection flow of fluid for various injectors
and their corresponding signal generators, whereby said system may
be used with a variety of injectors.
11. The injector system of claim 10, further including scale factor
means for maintaining said second signal proportional to the
injection flow of said fluid for various cross sections of said
syringe means, whereby said system can be used with a variety of
syringes.
12. The injector system of claim 1, the improvement further
comprising housing means for said injector and threaded shaft means
within said housing mechanically connected to said drive motor for
rotation therewith, ball nut means engaging the threads of said
threaded shaft, means mounted in said housing for preventing said
ball nut from rotating, where by rotation of said drive motor moves
said ball nut along the axis of said threaded shaft, piston tube
means extending along the length of said threaded shaft and having
an end portion extending beyond the end of said threaded shaft,
said end portion abutting said piston to drive said piston along
the axis of said syringe in response to the movement of said ball
nut.
13. The injector system of claim 12, said injector further
including removable connector means between said end portion of
said piston tube and said piston, whereby said piston tube can be
connected to said piston for driving said piston in two directions,
said piston tube being normally disconnected to permit said piston
to be driven only in a direction to eject said fluid from said
syringe.
14. The injector system of claim 13 wherein said sensing means
further includes compensating means for maintaining said second
signal proportional to said rate of flow for various mechanical
linkages between said drive motor and said piston.
15. The injector system of claim 1, the improvement further
comprising disposable syringe means for said injector, said
disposable syringe means including a disposable cartridge
containing said fluid to be ejected and a transparent pressure
jacket adapted to receive said cartridge and said piston means,
said pressure jacket preventing deformation of said cartridge when
said system is operative to apply pressure to said fluid to produce
said fluid flow, a housing for supporting said piston means, and
means for removably connecting said disposable syringe means to
said housing, said last-named means including retainer means
threadedly engaging said housing and having a central aperture
adapted to receive said pressure jacket, said pressure jacket
having a peripheral shoulder against which said retainer means
abuts to hold said pressure jacket and housing in assembled
relationship, whereby said pressure jacket can be removed from said
housing for replacement of said disposable cartridge.
16. The injector system of claim 15, further including electrically
insulating means interposed between said housing and said syringe
and said syringe means being electrically nonconductive, whereby
electric potentials on said housing are isolated from said
fluid.
17. The injector system of claim 15, wherein said piston means
comprises a piston head support and a flexible piston cap mounted
on said support, said cap being replaceable to permit said piston
means to be adapted to the internal diameter of said syringe
means.
18. The injector system of claim 17, the improvement further
comprising signal generator means responsive to the operation of
said motor for producing said second signal, and scale factor means
for maintaining said second signal proportional to the injection
flow of said fluid for various cross sections of said syringe
means, whereby said system can be used with a variety of
syringes.
19. The injector system of claim 1, the improvement further
comprising means for producing a voltage proportional to the output
torque of said drive motor, whereby the pressure developed in said
injection fluid can be monitored.
20. The injector system of claim 19, wherein said means for
producing a voltage proportional to the output torque of said drive
motor comprises a resistor in series with the armature of said
motor, said voltage being measured across said resistor and being
proportional to said fluid pressure.
21. The injector system of claim 20, wherein said drive motor is a
direct current, permanent magnet, torque-type motor having a
printed circuit armature for moving said piston means.
22. In an injector system for producing a controlled rate of flow
of injection fluid for use in angiography and having an injector
including syringe means for said fluid, movable piston means for
ejecting said fluid from said syringe means, a drive motor for
moving said piston, electrical control means including command
means for producing a command signal which is a function of a
desired rate of fluid flow, sensing means for producing a second
signal which is a function of the actual injection flow of said
fluid, and means for comparing said command and second signals to
produce a resultant signal for operating said drive motor at a
selectable, controlled rate to produce a desired flow of fluid
whereby the rate of flow of said injection fluid will be
substantially independent of flow-attenuating factors in the path
of said fluid, the improvement comprising electric circuit means
including a resistor connected to said drive motor for producing a
voltage proportional to the output torque of said drive motor, said
voltage being measured across said resistor and being proportional
to said fluid pressure.
23. The injector system of claim 22, wherein said drive motor is a
direct current permanent magnet, to torque-type motor having a
printed circuit armature, said resistor being connected in series
with said armature.
24. The injector system of claim 22, wherein said syringe means is
electrically nonconductive and includes a disposable cartridge and
a transparent pressure jacket adapted to receive said cartridge,
said cartridge containing a prepackaged quantity of said fluid to
be ejected, and said pressure jacket holding said cartridge in
operative position while said injecting pressure is generated in
said cartridge.
Description
This application relates, in general, to the medical science of
angiography, and, more particularly, to injection equipment for use
therein.
Angiography is a radiological technique wherein the arteries or
veins of a human or animal body are outlined by injecting suitable
contrast material therein, permitting X-ray photographs to be made
of the veins and arteries into which the material is injected.
Because of its diagnostic value, angiography is enjoying increased
use and many new instrumentation needs have arisen.
The contrast material used in angiography must be injected into the
desired vein or artery close to the area to be photographed and
immediately prior to making the photograph, for the flow of blood
therethrough generally dissipates the contrast material very
quickly. The material must, therefore, be injected through a long
thin tube, generally called a catheter, to the vascular site of
interest. Pressures as high as 1,000 p.s.i. have been used to
accomplish this injection and, traditionally, the controlling
injection variable has been the pressure setting on the injector
used to supply the contrast material. However, the injector
pressure setting is only one of the factors which determines
contrast material flow rate, other factors being the internal
diameter of the catheter, the catheter length, the contrast medium
viscosity, and the configuration of the flow path, and it is the
rate of flow of the contrast medium through the catheter in which
the angiographer is interested. It is highly important that these
factors be recognized, for failure to do so, and resultant reliance
on pressure setting alone, can produce unpredictable flow rates
under varying conditions. At best, such variations in flow rate
reduce the quality of the X-ray photographs, while at worst may
actually damage the vein or artery into which the material is being
injected. It is therefore an object of this invention to provide a
flow control injector system in which the operator can directly
select the rate of contrast medium injection without regard to the
many variables which affect flow rate.
Accurate knowledge of the contrast material discharge rate from the
catheter tip is required in order to insure that the angiographic
procedure is safe, for excessively high flow rates may cause
considerable damage. Another object of this invention, therefore,
is to provide means for monitoring and recording the actual
pressure that is being used to accomplish the injection. A related
object of the invention is to provide means for protecting the
patient from such damaging flow rates by providing a rate trip
network in the control circuitry of the present injector equipment,
whereby the injection will be stopped in the event of a system
failure that might lead to an injection rate higher than the
operator command rate.
In the design of an injection system, a number of practical
considerations should be taken into account. Space around an X-ray
table is limited. Further, the catheter entrance point in the body
of the patient, and, consequently, the ideal position of the
injector tip with respect to the patient is variable, and is a
function of patient size, position and the exact puncture site. For
these reasons, a small injector that may be freely positioned in
space around the X-ray table surface is a desirable end. With
increased experience, angiographers have learned to place catheter
tips in selective small flow areas where injection rates of 1 to 10
cc. 3 s per second are adequate for radiological opacification of
the vessels under study.
An injector to satisfy the foregoing selective angiographic needs
should be very small, should be injection rate-controlled and
should be capable of being hand held or freely positioned around
the injection site. It is therefore an additional object of the
invention to provide an angiographic injector system which is
compact and easily movable, yet is capable of providing a
rate-controlled flow of sufficient volume to meet the needs of the
art.
Inasmuch as the techniques of angiography may be applied in many
parts of the body, all of which require different flow rates and
which may require different quantities of contrast material, it
follows that there is a need for a series of injectors all of which
are injection rate-controlled, but differing in size and work
capacity. However, such a series of injectors would multiply the
cost of angiography, and make it less useful as a diagnostic tool.
In order to avoid the duplication of such a series of injectors,
and thus substantially to reduce the cost of such a series, the
present invention provides a common power source and control system
for use with a plurality of injectors and cartridges of differing
size and capacity.
Prior art injectors, as well as that of the present invention, are
electrically operated, and as a result an electrical potential is
established in the injector. The prior injector art does not
attempt to electrically insulate the contrast medium from this
electrical potential. Rather, attempts are made to maintain the
patient at the same potential as the injector. However, recent
evidence has shown that voltages and currents as low as 100
millivolts and 100 microamperes transmitted from an injector
through a catheter to the heart may cause a fatal heart condition
known as ventricular fibrillation. It is an object of this
invention to avoid this danger by packaging the contrast material
in nonconductive plastic and rubber syringes to insulate the
patient from the injector. It is a further object of this invention
to protect these plastic syringes from explosion during a high
pressure injection by protecting them with a pressure jacket.
These and other objects and features of the invention will become
apparent to those skilled in the art from the following description
of a preferred embodiment thereof, taken in conjection with the
accompanying drawings, in which:
FIG. 1 is a schematic diagram of a control circuit for a flow rate
controlled injector system;
FIG. 2 illustrates in graphical form the operation of the rate trip
circuit of FIG. 1;
FIG. 3 is a side plan view, partly in cross section and partly
broken away, of an injector suitable for use with the control
circuit of FIG. 1; and
FIG. 4 is a cross-sectional side plan view of a modified syringe
and supporting pressure jacket suitable for use in the injector of
FIG. 3.
Turning now to a consideration of the circuit of FIG. 1, there is
illustrated a control system by means of which the operator of the
injector system may select an injection flow rate that will be
delivered and maintained regardless of the various flow attenuating
factors mentioned above. A command voltage directly proportional to
the desired injection rate is established by adjustment of a
potentiometer 10 having a linear resistor portion 12 connected
between a source of reference voltage 14 and a ground point and a
slidable arm 16. Movement of the slidable arm by the operator
determines the magnitude of the voltage applied through a line 18
to an amplifier 20, and thus determines the flow rate, motion of
the arm causing a varying flow rate, while a selected position
produces a selected constant rate. A tachometer generator 22, which
is mechanically linked to the shaft of the injector drive motor 24
by way of linkage 26, generates a feedback voltage at its terminals
that is directly proportional to the actual injection rate, for as
will be described hereinafter, the rate of flow must be directly
proportional to the speed of motor 24 because of the nature of its
direct drive mechanism. This feedback voltage, which has a polarity
opposite to that of the command voltage, is applied by way of line
28 to a generator compensating voltage divider 30 comprised of
resistors 32 and 34 connected in series across generator 22. This
voltage divider permits compensation of the control circuitry for
different injectors which may have different mechanical linkages
and generator output voltages. Selector switch 36 permits selection
of the desired voltage level for application through line 38 to a
scale factor voltage divider 40 which compensates the feedback
voltage for various syringe cross sections, thus permitting the
user of different sized syringes with a selected injector device.
Voltage divider 40 is comprised of the series arrangement of
resistors 42, 44 and 46 connected between line 36 and ground, and a
selector switch 48 for applying the desired voltage level through
line 50 to the input of amplifier 20. Since the feedback and
command voltages are of opposite polarity, the algebraic sum of the
magnitudes of these voltages at the input of amplifier 20
constitutes an error signal which corresponds to the difference
between the desired and the actual injection rates.
The voltage dividers 30 and 40 are provided because it has been
found that considerable savings in the cost of injector systems as
well as in the space used by such systems, in addition to increased
versatility of the system, can be effected if the injector system
consists of a single power and control unit which services
different size injectors which, in turn are capable of using
different size syringes. Voltage divider 30 will then compensate
for feedback voltage differences between, for example, a large,
high-pressure injector and a small, hand-held injector. Voltage
divider 40 will compensate for cross-sectional differences in the
syringes used. To provide this versatility, the feedback voltage
from the generator 22 is scaled by various constants that
correspond first, to the generator voltage output per linear
velocity unit of the piston used to drive fluid out of the syringe,
and second, to the injection rate of the fluid per linear velocity
unit of the piston travel. An example of the first compensating
factor involves the use of an injector unit which produces a higher
generator feedback voltage per unit piston travel velocity than the
setting of the control unit which is to be used with the control
unit. Voltage divider 30 permits compensation for such an event,
thus allowing interchangeability between control units and
injectors, or interchangeability of injectors with a given control
unit. If resistors 32 and 34 are chosen so that R34/R32+R34 equals
the ratio of the lower to higher generator voltage outputs per
velocity unit of piston travel for two injector units, then they
will be interchangeable in the control unit.
The injection rate from a syringe is directly related to the piston
velocity multiplied by a scale factor which corresponds to the area
of the syringe piston i.e., to the diameter of the syringe. The
voltage signal which represents the actual injection rate can be
held within the desired limits of accuracy, even though syringes of
different cross-sectional areas are used. This is done by means of
scale factor voltage divider 40. In the illustrated embodiment,
with switch 36 in the position shown, the voltage divider is set
for the largest of three syringes having different cross-sectional
areas, and provides the maximum voltage output. By positioning
switch 48 between resistors 42 and 44, the feedback voltage is
proportional in injector flow rate for a syringe of smaller cross
section. To maintain this proportion, the relationship
R44+R46/R42+R44+R46 must equal the ratio of the cross-sectional
area of the smaller syringe to the larger syringe. A still smaller
syringe may be used if the voltage between 44 and 46 is picked up;
thus, with a feedback voltage signal exactly proportional to the
injection rate, different injectors utilizing different syringes
may be controlled by a common control and power module.
The error signal which appears at the input of high gain amplifier
20 is amplified and fed through line 52 to the base of transistor
54. This transistor acts as a buffer amplifier between amplifier 20
and the bases of parallel-connected power transistors 56, 58, 60
and 62. The collectors of the power transistors are connected to a
common low impedance power source at 64, and the emitters are each
connected through current limiting, low resistance, forward-biased
diodes 66, 68, 70 and 72, respectively, to a common line 74. The
current limiting diodes are provided to prevent excessive emitter
degeneration. Line 74 is connected through contact 76 of the on-off
relay coil 78 and thence through line 80 to the armature of motor
24. As illustrated in FIG. 3, the motor may be a permanent magnet,
direct current, torque type, having a printed circuit armature. The
return motor lead is connected by line 82 through a resistor 84 and
a diode 86 to ground.
Utilizing the linear relationship which exists in this type of
motor between the motor output torque and the input current, the
voltage drop, due to the armature current, which appears across
resistor 84, will be directly proportional to motor output torque
and thus to the pressure generated by the injector. Diode 86 is
chosen such that its voltage drop corresponds to the amount of
motor output torque taken up by the mechanical friction of the
injector. The voltage across resistor 84 may then be measured at
terminals 88 and 90, and used for pressure sensing and recording
purposes.
In operation, the rate of rotation of motor 24, which rate is
proportional to the actual injection flow rate from the syringe, is
measured by means of a generator 22, producing a rate voltage. This
injection rate voltage is compared to a command voltage
representing the desired injector rate, and any error signal is
amplified and used to control the conductivity of the parallel
power transistors 56, 58, 60 and 62 connected in series with the
motor to control its torque. The control system responds to an
error signal to insure that the torque exerted by the motor on the
piston of the syringe is sufficiently great to produce the desired
flow characteristics regardless of variations in flow attenuation
in the injector or the catheter.
Should the control system fail, an over-rate condition might result
that could deliver an excessive flow of the contrast medium to the
patient. To protect against this possibility, a rate trip circuit
is provided as follows. A potentiometer 94, having resistor portion
96 and sliding arm 98, is ganged by means of mechanical linkage 100
with the injector rate command potentiometer 10, but differs from
element 10 in that it has an exponential, rather than a linear,
response curve and, further, has a decreasing voltage output with
clockwise rotation of slidable arm 98 instead of the increasing
voltage with clockwise rotation of arm 16 used in potentiometer
10.
The conceptual basis for the rate trip circuit is illustrated in
FIG. 2, wherein curve A represents the exponential output of
potentiometer 94 with clockwise rotation of its slidable arm, while
curve B represents the linear output of potentiometer 10 with
clockwise rotation of its slidable arm. Curve C represents the
product of curves A and B.
Resistor portion 96 of potentiometer 94 is connected through lines
102 and 50 to the input of amplifier 20, and thus the voltage
appearing at this input is applied to resistor portion 96. The
output voltage on slider arm 98, therefore, is the product of the
settings of arms 16 and 98, which product is represented by curve C
of FIG. 2. Resistor 104 is connected in series with potentiometer
94 in order to maintain an output voltage on arm 98 that is above
ground, so that the voltage represented by curve C does not fall to
zero when the injection command voltage is at its maximum
value.
The output appearing on arm 98 is applied through line 106 to the
emitter of a unijunction transistor 108. This transistor type is
utilized because of its extremely low emitter current when in the
"off" condition and because, at a predictable threshold voltage
(indicated by curve D in FIG. 2), which equals a known fraction of
the interbase voltage, the transistor 108 will fire and produce a
voltage pulse on electrode 110 which is fed through a diode 112 to
the control electrode 114 of a silicon controlled rectifier (SCR)
116. The SCR is thus triggered into a self-latching "on" condition,
allowing current to flow through relay coil 120 and normally closed
switch 122 to ground from voltage source 124. Energization of relay
coil 120 shifts its normally closed contact 126 to open the current
path from source 124, through contact 126, through line 128,
through master "on-off" switch 130 and through relay coil 78 to
ground. This deenergizes coil 78, allowing contact 76 to open and
halt the injection. Opening of switch 122 allows the SCR 116 to
return to its nonconductive state, thus permitting relay coil 120
to be deenergized and relay coil 78 to be reenergized. This resets
the rate trip circuit and conditions the injector control system
for further generation. Diode 112 allows only a positive pulse from
transistor 108 to trigger the SCR 116. The unijunction transistor
108 is biased by a resistor 132 connected between electrode 134 and
voltage source 124 and by a resistor 136 connected between
electrode 110 and ground.
By selecting appropriate values for reference voltage sources 14,
and 124, the characteristics of potentiometers 10 and 94 and the
value of resistor 104, one can specify the shape of curve C (FIG.
2) which, under normal operational conditions will be a known
percentage below threshold curve D. Curve D is, in turn, a function
of the reference voltage 124, the operating characteristics of
unijunction transistor 108, and the value of resistors 132 and 136.
However, should an over-rate condition occur through a control
system failure, the voltage seen by the arm 98 of potentiometer 94
would rise to the threshold voltage of the unijunction transistor
108, firing the transistor and activating the trip mechanism to
stop the injection. An alternative method of activating the
unijunction is to compare the command rate voltage with the
feedback voltage in a differential amplifier, the output of this
amplifier triggering the unijunction transistor when the feedback
signal exceeds the command signal by a present amount.
Turning now to a consideration of the structure of an injector
device suitable for use with the control system above-described
there is illustrated in FIG. 3 an injector syringe mechanism 152
which is particularly designed for hand-held use. The injector
mechanism is constructed for lightness and compactness, without
sacrificing the required power, and thus is driven by direct
current permanent magnet motor 24 having a printed circuit armature
154. The shaft 156 of the motor is drivingly coupled to a threaded
screw shaft 158 for rotation with the motor armature 154.
Threadedly engaging shaft 158 for rotation with the motor armature
154. Threadedly engaging shaft 158 is a ball nut 160 which is
prevented by pin 162 from rotating, but which is free to move
axially along shaft 158, the pin sliding in a guide slot 164 formed
in a guide bar 166 supported in the housing 168 of the injector
150. The axial movement of ball nut 160 in response to rotation of
threaded shaft 158 converts the rotary motion of motor 24 to linear
motion. Ball nut 160 is connected to a piston tube 170 which moves
with the ball nut along shaft 158. The outer end of the tube is
supported, during its linear motion, by an oil seal 172 secured in
an opening 174 at one end of housing 168. Piston tube 170 abuts
directly against a piston head support member 176, which, in turn,
provides mechanical support for a rubber piston cap 178. A syringe,
or cartridge, 180 is mounted on the injector housing 168 by means
of an internally threaded nut 182 adapted to engage external
threads on the end of the housing 168. Nut 182 has a centrally
located aperture 184 which receives the syringe and a seal member
186 to permit an airtight fitting on the end of the housing. A
flanged portion 188 is provided on the end of the syringe which
faces the housing to facilitate a tight seal between sealing
members 174 and 186 when nut 182 is tightened.
The internal diameter of the syringe and the external diameter of
piston 176 are selected to provide the clearance required to permit
the flanged edge 190 of rubber piston cap 178 to seal the interior
of the syringe. It will be apparent that different sizes of
syringes will require pistons having varying diameters, but the
construction of this mechanism is such that the various sizes are
easily connected to the injector drive mechanism. The aperture in
nut 182 is sufficiently large to permit larger syringes than that
illustrated, while by providing smaller diameter syringes with
sufficiently large flanges, they can be used with this equipment as
well. Piston member 176 and cap 178 may be driven in a forward
direction (toward the right as viewed in FIG. 3) by piston tube 170
without any mechanical connection being made between the piston and
the tube. This arrangement is often used where it is essential to
prevent reversal of the motion of the piston. Alternatively, piston
176 may be connected to piston tube 170 by means of screws 192, to
permit both forward and reverse driving of the piston. It will be
apparent that forward motion of the piston will expel fluid or any
other matter within the syringe 180, such as contrast medium 194.
If the piston is attached to the piston tube 170, reverse driving
can be used to fill the syringe with the desired amount of contrast
material while the syringe is attached to the injector drive
mechanism.
The broken-away portion of motor 24 illustrates, in addition to
armature 154, the arrangement of the permanent magnet 196. In
operation, direct current is commutated to the armature conductors,
an the resultant alternating magnetic field interacts with the
stationary magnetic field of the permanent magnet to produce torque
on shaft 156. Gears 198 and 200 provide a mechanical linkage of
known gearing ratio between the motor shaft and tachometer
generator 22. The use of a printed circuit armature, permanent
magnet torque motor allows maximum power for minimum size and makes
practical a hand-held injector much smaller than conventional
electromechanical injectors.
Where greater injection power is required than can be delivered by
the hand-held unit, a larger injector unit may be provided and
mounted, for example, upon a suitable base member. Such a unit
would require a more powerful motor and thus would not, as a
practical matter, be a hand-held unit. However, both injectors
would use the same power and control unit, being connected to that
unit through suitable multiconductor connectors. It is contemplated
that the power and control unit would be mounted, for example, in
an instrument console adjacent an X-ray table, with a connector
jack located at or on the table. A series of injectors would then
be available for various uses, each one being plugged into the
connector jack as needed. If desired, each injector may be
connected to the power unit through some common and some individual
conductors so that the proper compensating resistors would
automatically be connected in circuit upon connection of a
particular injector.
When the small, hand-held injector mechanism is used, the pressures
involved are relatively low, in the neighborhood of 150 p.s.i. and
a disposable plastic syringe or contrast medium cartridge may be
used. However, when greater injector power is required, such
containers are entirely inadequate, and they tend to explode long
before the pressures of 800 p.s.i. used in angiography are
encountered. This tendency has prevented the use of plastic
containers in angiography, the accepted materials being glass for
the smaller units and stainless steel for the more powerful units.
This type of construction made the use of disposable containers out
of the question, and required reuse, with its attendant danger of
infection. The present invention overcomes the problem of container
explosion and permits the use of disposable syringes or cartridges
by providing the modified syringe mounting illustrated in FIG. 4,
wherein a pressure jacket 210 is utilized to prevent the enclosed
syringe 212 from bursting when injection pressures in excess of the
strength limitations of the syringe are used. The pressure jacket
is made to fit exactly the syringe, cartridge or ampule being used
in the injector. This exact fit is obtained by making a positive
mold of the syringe, the mold preferably being of metal. A
high-strength, transparent plastic, such as styrene, acrylic
polycarbonate or epoxy, is formed around the metal mold to a
thickness sufficient to withstand the anticipated pressure. A
circumferential flange is formed around the molded plastic to
provide a bearing surface for the longitudinal forces exerted
during injection. Preferably the syringe is slightly tapered toward
the discharge end so that it can easily be inserted into and
removed from the jacket. It will be apparent that the pressure
jacket can be machined to the proper fit, if desired, but the
molding process is preferred. With the internal dimensions of the
jacket exactly corresponding to the outside dimensions of the
syringe, the syringe is protected against the pressure induced by
the driving of piston 176 against the resistance offered by a
restricted flow path connected to the syringe tip 214.
Although prior automatic injectors have illustrated fluid
containers resting in jackets of various types, these prior jackets
have been no more than positioning devices designed to align the
containers with the injector devices. Since the prior art
contemplated low flow rates at low pressures, and did not
anticipate the art of angiography, the container devices were not
intended to withstand high pressures, and were not capable of doing
so.
By making the pressure jacket of a high strength, transparent
molded plastic material, the operator of the device not only may
visually monitor the progress of the piston and the amount of fluid
remaining in the syringe, but may also inspect the contrast medium
for air bubbles and the like. The jacket is mounted on the external
threads of housing 168 by means of a connecting nut 216 having
internal threads 218. A central aperture 220 in nut 216 receives
the pressure jacket 210, the connecting nut abutting against
shoulder 222 of the jacket to force the syringe against housing
168. An elastic bearing member 224 is interposed between nut 216
and the bearing surface of shoulder 222 for the purpose of evenly
distributing the transmission of longitudinal force. Syringe 212 is
provided with a flange 226 which abuts against housing 168 when
properly seated, as described with respect to syringe 180 in FIG.
3. However, this flange serves an additional purpose in the present
embodiment in that it is designed to extend a short distance out of
the pressure jacket, leaving a small space 228 to allow the syringe
to be grasped by flange 226 for removal from the pressure
jacket.
The construction of the pressure jacket permits the use of a
disposable, preloaded syringe of lightweight glass or plastic,
providing a quick, convenient method of loading an injector while
at the same time providing insurance against the transmission of
infection from one patient to another. Although the syringe shown
in the accompanying drawings does not include a plunger means, but
relys on the injector plunger 170 to drive the contrast medium out,
it will be apparent that the injector can be modified to accept
syringes which are manufactured with a plunger. Such a construction
would permit the manufacture of a disposable plastic syringe,
prepackaged to contain the contrast medium, which could be used for
manual injections, could be used in the small, hand-held injector,
or could be used in the larger injector after insertion in a
pressure jacket.
Although the syringes in FIGS. 3 and 4 are shown without closure
means on the outlet tips, it will be apparent that appropriate
means would be provided for a prepackaged syringe. It is preferred
that the outlet tips also be provided with Luer-Lok fasteners for
easy attachment of catheters and the like.
Thus, there has been provided a compact, inexpensive injection
apparatus designed for use in angiography. This invention
recognizes that the major factor in the injection of contrast fluid
is the maintenance of a constant flow rate, rather than of a
constant pressure, and the system is accordingly directed to an
injector apparatus and control circuit capable of producing this
type of operation. The result is an angiographic injector having
improved operating characteristics over prior art devices, but
which eliminates the complexity and bulk of the prior art. The
invention also recognizes that on occasion a variation in flow rate
may be desired, and thus there is provided a command voltage which
is proportional to the desired flow. This command voltage may be
derived from the slide arm of a potentiometer, or from some other
suitable source, and may be varied in either direction. The system
will respond to any changes in the command voltage to produce a
corresponding variation in the flow rate, and it will be apparent
that the flow rate will thus be a function of the command voltage.
These, and such other modifications of the described embodiment as
will become apparent to those skilled in the art, are within the
spirit and scope of the present invention as defined by the
following claims.
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