U.S. patent number 3,613,689 [Application Number 05/002,491] was granted by the patent office on 1971-10-19 for cryosurgical apparatus.
This patent grant is currently assigned to Frigitronics of Conn., Inc.. Invention is credited to Ralph E. Crump, Frank L. Reynolds, Carl R. Tillstrom.
United States Patent |
3,613,689 |
Crump , et al. |
October 19, 1971 |
**Please see images for:
( Certificate of Correction ) ** |
CRYOSURGICAL APPARATUS
Abstract
A cryosurgical apparatus primarily adapted for use with gases
which cool when expanded from a high-pressure state to a
low-pressure state. The apparatus includes an expansion chamber
which receives gas through a supply tube. The gas is supplied from
a selector valve at either a high pressure or a low pressure. The
supply tube includes a self-acting valve which is normally biased
open when gas is supplied at low pressure but is forced closed by
gas under high pressure. With the valve open, the expansion chamber
is filled with the low-pressure gas and is substantially at room
temperature. When the valve closes, high-pressure gas bypasses the
automatic valve and enters the cooling chamber through a small
orifice, expanding to a low-temperature state and cooling the
expansion chamber.
Inventors: |
Crump; Ralph E. (Trumbull,
CT), Reynolds; Frank L. (Monroe, CT), Tillstrom; Carl
R. (Fairfield, CT) |
Assignee: |
Frigitronics of Conn., Inc.
(Bridgeport, CT)
|
Family
ID: |
21701033 |
Appl.
No.: |
05/002,491 |
Filed: |
January 13, 1970 |
Current U.S.
Class: |
606/23 |
Current CPC
Class: |
A61B
18/02 (20130101); F25B 9/02 (20130101); F25B
2309/021 (20130101); A61B 2018/0281 (20130101); F25B
2309/022 (20130101) |
Current International
Class: |
A61B
18/00 (20060101); A61B 18/02 (20060101); F25B
9/02 (20060101); A61b 017/36 () |
Field of
Search: |
;128/303.1,400,401
;62/293 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Trapp; L. W.
Claims
What is claimed is:
1. Cryogenic apparatus which comprises: a tip member defining a
low-temperature expansion chamber; a supply tube communicating with
said chamber; an exhaust tube communicating with said chamber,
means for selectively injecting a fluid into said supply tube at
either of a high pressure or a low pressure; inlet valve means in
said supply tube between said injection means and said chamber,
said valve means being normally biased open when said fluid is at
said low pressure but closed under the influence of fluid at said
high pressure; and means forming a fluid orifice between said
supply tube and said chamber and bypassing said valve means.
2. The apparatus of claim 1 wherein the end of said supply tube
adjacent said chamber defines an inlet opening therethrough and
said inlet valve means comprises a valve member operable to close
said inlet opening.
3. The apparatus of claim 2 wherein said valve member comprises a
ball.
4. The apparatus of claim 1 wherein said valve means includes a
spring normally biasing said valve means to its open position.
5. The apparatus of claim 4 wherein the end of said supply tube
adjacent said chamber defines an inlet opening therethrough and
said inlet valve means comprises a valve member operable to close
said inlet opening.
6. The apparatus of claim 5 wherein said valve member comprises a
ball.
7. The apparatus of claim 5 wherein said valve member comprises a
needle.
8. The apparatus of claim 1 wherein said injecting means comprises
a selector valve.
9. The apparatus of claim 1 wherein said injecting means comprises
a source of high-pressure gas; means for reducing said high
pressure to a low-pressure range; and selector valve means for
bypassing said reducing means and admitting high-pressure gas from
said source to said supply tube.
10. Cryosurgical apparatus which comprises: a hand-held casing; a
tubular tip member extending from said casing defining at its end a
low-temperature expansion chamber; a supply tube within said tip
member and forming an annular exhaust passage therewith, the end of
said supply tube being adjacent said chamber and defining an inlet
opening therethrough; a source of high-pressure gas; a source of
low-pressure gas; selector valve means selectively admitting said
high-pressure gas or said low-pressure gas to said supply tube; an
inlet valve member positioned within said supply tube to close said
inlet opening under the influence of said high-pressure gas; spring
means normally biasing said inlet valve member away from said inlet
opening under the influence of said low-pressure gas; and means
forming a gas orifice between said chamber and said supply tube and
bypassing said inlet opening when closed by said inlet valve
member.
Description
BACKGROUND OF THE INVENTION
This invention relates to cryogenic apparatus and is disclosed
herein primarily in connection with apparatus for cryosurgery. Its
applications, however, are not so limited and it may be employed
wherever its unique advantages are desirable.
In U.S. Pat. Nos. 3,393,679 of Crump et al. and 3,451,395 of
Thyberg there are disclosed cryosurgical instruments primarily
designed to employ low-boiling liquids as the cooling media. The
most commonly used liquids are the halogenated hydrocarbons. The
device disclosed in each of those patents comprises a hand-held
housing from which extends a low-temperature probe. The tip of the
probe may be selectively warmed or cooled by depression of a lever
on the housing. In its warming position, the lever opens the fluid
supply valve and closes an exhaust valve so that the instrument is
completely filled with liquid at room temperature. In its freezing
position, the lever closes the inlet valve and opens the exhaust
valve. The fluid is then admitted to the probe through a small
orifice which bypasses the inlet valve. The fluid boils in the
probe tip, causing it to be cooled and the resulting vapor is
withdrawn through the exhaust valve.
Devices of the foregoing type have achieved outstanding commercial
success. In many parts of the world, however--particularly in
underdeveloped regions--supplies of low-boiling liquids are not
readily obtainable. However, high-pressure gases which exhibit
cooling upon expansion, such as, for example, by Joule-Thomson
effect, are quite readily available. One such gas, for example, is
nitrous oxide, the well-known "laughing gas" which is extensively
used throughout the world as an anesthetic. It would, accordingly,
be desirable to provide a cryosurgical instrument which could
utilize such gases as the cooling medium. It would also be
desirable to provide a cryosurgical apparatus which could be
actuated remotely, as from a foot-operated valve, to avoid hand
fatigue which may result from use of a finger lever. Accordingly,
it is the primary object of the present invention to provide
improved cryosurgical apparatus which may be operated from a source
of high-pressure gas. Other objects are to provide apparatus which
may be selectively warmed or cooled by operation of a remote
control; to provide such an apparatus which does not require a
finger-operated lever; and to provide such apparatus which is
adapted for use in a number of cryogenic applications.
SUMMARY OF THE INVENTION
In accordance with this invention there is provided a cryogenic
apparatus comprising a tip member defining a low-temperature
low-temperature expansion chamber. A supply tube and an exhaust
tube communicate with the chamber. Means are provided for
selectively injecting fluid into the supply tube at either a high
pressure or a low pressure. Included in the supply tube between the
injection means and the chamber is an inlet valve which is normally
biased open when the fluid is at the low pressure but closes under
the influence of fluid at the high pressure. Means are also
provided which form a fluid passage between the supply tube and the
chamber, bypassing the valve.
BRIEF DESCRIPTION OF THE DRAWINGS
The manner in which the objects of the invention are achieved may
be best understood by reference to the following description taken
in connection with the attached drawings wherein:
FIG. 1 is a schematic illustration of a cryogenic system in
accordance with this invention;
FIG. 2 is a longitudinal cross section of a portion of a
cryosurgical instrument incorporating this invention;
FIG. 3 is an enlarged illustration of the tip of the instrument of
FIG. 2;
FIG. 4 is a cross-sectional view illustrating a modification of the
invention;
FIG. 5 is a cross-sectional view of a further modification of the
invention;
FIG. 6 is a cross-sectional view of a still further modification of
this invention;
FIG. 7 is an enlarged partial cross-sectional view of a still
further modification of the invention; and
FIG. 8 is a longitudinal cross section of a still further
modification of this invention.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
In FIG. 1 there is illustrated a cryogenic system including a
supply bottle 10 of a suitable pressurized gas. This may be, for
example, nitrous oxide at a pressure of 800 p.s.i. Associated with
the bottle is the usual shutoff valve 12. Gas is supplied by a
delivery line 14 through an auxiliary shutoff valve 16 which may be
mounted in a control cabinet which also carries a pressure gauge
18. The delivery line branches at a tee 20. A three-way valve 22
includes ports 24, 26, 28. Port 24 is connected to one of the
delivery line branches. The other branch of the delivery line
passes to metering needle valve 30. The outlet of needle valve 30
is connected to a heat exchanger coil 32 which exhausts into a
further tee 34 connected to port 26 of valve 22 and to a supply
line 36 extending into a cryosurgical instrument 38. Port 28 of the
three-way valve 22, is connected through a relief valve 40 to an
exhaust muffler 42. Relief valve 40 is set to open at a
predetermined pressure, such as 50 p.s.i. The three-way valve 22
may be controlled by any suitable means, such as a foot lever, and
is designed to selectively interconnect port 26 with either port
28, as shown, or port 24. In the illustrated position, the
high-pressure gas supply is shut off at port 24. However, it passes
through the needle valve 30 which reduces the output pressure to
25-50 p.s.i. This gas passes through the heat exchanger 32 where
its temperature is raised to substantially that of the ambient air
and this warm low-pressure gas passes through supply line 36 into
the instrument 38. If, for any reason, the pressure should increase
above the 50 p.s.i. level of relief valve 40, this valve will open
permitting the gas to escape through the exhaust muffler 42.
When three-way valve 22 is actuated from the position illustrated
in FIG. 1, it will interconnect ports 26 and 24. This will permit
high-pressure gas to pass directly from the bottle 10 into the
supply line 36 of instrument 38. As the pressure on both sides of
needle valve 30 will then be substantially equal, there will be
essentially no flow through the valve.
It will now be seen that the above-described apparatus permits
either high-pressure or low-pressure gas to be selectively applied
to the cryosurgical instrument 38. The construction of instrument
38 will now be explained with particular reference to FIG. 2. It
comprises a hand-held tubular casing 44 closed at one end by a
nosepiece 46 and having near its other end a wall 48. A plug 50
extends through the wall 48 and is connected rearwardly to the end
of supply line 36. Supply passages 52 in plug 50 permit gas to flow
from the supply line 36 to a tubular inner chamber 54 secured to
the inner end of plug 50. Inner chamber 54 is shorter and of
smaller diameter than casing 44 so as to define therewith an
annular exhaust passage 56 which communicates with atmosphere, or
other suitable exhaust, through exhaust ports 58 in wall 48.
Extending forwardly from nosepiece 46 is a tubular probe 60 which
is offset at its end to form an expansion chamber 62.
Concentrically positioned within the probe 60, and of smaller
diameter, is a supply tube 64 connected at one end to inner chamber
54 and having its remote end adjacent the expansion chamber 62.
Referring to the enlarged view of FIG. 3 it will be seen that this
remote end 66 of supply tube 64 defines an inlet opening 68.
Extending radially from the inlet opening 68 is a small bypass
orifice 70. Mounted within the inner chamber 54 is a coil spring
72. One end 74 of the spring extends through the plug 50 where it
is secured as by brazing or a suitable weld 76. The opposite end 78
extends into the supply tube 64 where it is terminated with a small
loop 80. Secured to loop 80 by another loop 82 is a short wire 84
which carries at its end a ball 86. The ball 86 is positioned
closely adjacent the inlet opening 68 but is normally displaced
therefrom by the action of spring 72. Although the sizes of the
various parts may be varied to suit the particular application, in
one embodiment the diameter of the ball 86 was 0.046 inch and it
was spaced from opening 68 by approximately 0.060 inch. Ball 86 is
slightly smaller than the inner diameter of the supply tube 64.
To explain the operation of the apparatus of FIGS. 1-3 it will be
assumed that the valve 22 is in the position illustrated in FIG. 1
so that, as previously explained, only low-pressure gas is applied
through line 36. This gas enters the cryosurgical instrument 38
through supply passages 52, inner chamber 54, and supply tube 64.
It passes around the ball 86 and through inlet opening 68 into
chamber 62. From chamber 62 it flows rearwardly through probe 60,
and exhaust passage 56, out exhaust ports 58. As the gas is
essentially at room temperature, it will be seen that the probe and
the expansion chamber 62 will be warm. To cause the instrument to
freeze, the three-way valve 22 is actuated to supply high-pressure
gas directly to the cryosurgical instrument 38. This high-pressure
gas flows into the instrument through the same line and in the same
manner as at low pressure. However, the additional pressure acting
upon ball 86 forces it outwardly and against the inlet opening 68
against the force of spring 72. The ball then closes opening 68 as
shown in FIG. 3. The only path for the high-pressure gas-filling
supply tube 64 is now through the bypass orifice 70. Accordingly,
it escapes through this orifice and expands into the much reduced
pressure of expansion chamber 62, thus becoming cool and extracting
heat from the walls of the chamber and from any tissue which the
chamber may contact. The cool exhaust gas then passes rearwardly
through the instrument and exhausts in the same fashion as
previously described.
It will now be apparent that, by means of this invention including
the self-acting valve, it is possible to utilize high-pressure
gases as efficient cooling media for cryosurgical instruments. It
will also be apparent that such instruments may be selectively
warmed or cooled by a remotely located valve, such as a valve
controlled by a foot pedal.
A number of variations of this invention are possible and several
such are illustrated in FIGS. 4-8. FIG. 4, for example, illustrates
an embodiment wherein a separate piston is used to control the
position of ball 86. In this embodiment, the inner chamber 54 is
shortened to form a cylinder housing a piston ball 88 to which is
secured a wire 90 carrying ball 86. The piston 88 is forced
rearwardly by coil spring 92 and it advances against the coil
spring under the influence of high-pressure entering the rear of
the chamber 54.
In FIG. 5 is illustrated a modification which may be of particular
value for applications involving a relatively long probe, such as
might be required for brain surgery or for brain implants in
laboratory animals. In this embodiment, the supply tube 64 includes
a right angle extending downwardly through the probe 94. The ball
96 is mounted on the end of a wire 98 which is normally biased
upwardly by a leaf spring 100. FIG. 6 illustrates a curved probe
102 wherein the ball 104 is mounted on the end of a curved wire 106
having an integral spring 108. The opposite end of the wire is
carried by a member 110 which threadedly engages a suitable bracket
112 to permit accurate and adjustable location of the ball.
In the FIG. 7 modification, the end 66 of supply tube 64 is
substantially spherical. The ball 114 is loosely positioned within
the end 66 and retained by means of dimples 116 formed in the tube
64. A coil spring 118 is positioned on the outer surface of tube 64
and has an end 120 which extends through inlet opening 68 and bears
against ball 114, tending to keep it in the rearward position.
In the FIG. 8 modification the ball is replaced by wire 122 having
at its end a valve needle 124 for engaging the inlet opening. At
its other end wire 122 has an enlarged head 126 biased rearwardly
by a spring 128. Head 126 is forced outwardly by increased
pressure.
It will be apparent to those skilled in the art that, by means of
this invention, all of the objectives set forth have been achieved.
It will also be apparent that a number of variations and
modifications may be made therein without departing from the spirit
and scope of this invention. Accordingly, the foregoing description
is to be construed as illustrative only, rather than limiting. This
invention is limited only by the scope of the following claims.
* * * * *