U.S. patent number 3,602,229 [Application Number 04/755,041] was granted by the patent office on 1971-08-31 for a method of fibrillating a heart and apparatus therefor.
Invention is credited to Johannes Petrus Gous, George Gustav Jaros, Johan Samuel Loubser, Johannes Christiaan Van Der Spuy.
United States Patent |
3,602,229 |
Jaros , et al. |
August 31, 1971 |
**Please see images for:
( Certificate of Correction ) ** |
A METHOD OF FIBRILLATING A HEART AND APPARATUS THEREFOR
Abstract
Fibrillation of a heart by inducing arrhythmias in the heart
muscle fibers separately and successively in small groups by the
application of a multiple of low voltage electrical pulses across
the surface of the heart. The flow of electrical current is
concentrated along the outer surface of the heart. A fibrillator
comprising pulse-generating means housed within a small casing
having a pair of electrodes on the outer surface of the casing and
connected operatively to the pulse-generating means, the
fibrillator being in the form of a single self-contained unit and
being sterilizable as a whole by introduction into a sterilizing
zone.
Inventors: |
Jaros; George Gustav (Arcadia,
ZA), Gous; Johannes Petrus (Sunnyside, ZA),
Loubser; Johan Samuel (Deerness, ZA), Van Der Spuy;
Johannes Christiaan (Waterkloof Ridge, all of Pretoriz,
ZA) |
Family
ID: |
27130959 |
Appl.
No.: |
04/755,041 |
Filed: |
August 26, 1968 |
Foreign Application Priority Data
Current U.S.
Class: |
607/72 |
Current CPC
Class: |
A61N
1/362 (20130101); A61N 1/385 (20130101) |
Current International
Class: |
A61N
1/362 (20060101); A61n 001/38 () |
Field of
Search: |
;128/419R,418,421,206,422,423,419D,419P,407,405,303.1,303.13 |
References Cited
[Referenced By]
U.S. Patent Documents
Other References
Cammilli et al., "Annals of the New York Academy of Sciences," Vol.
III. Art. 3, pp. 1007- 1029, June 11, 1964 Conly pp. 1007- 1013
relied on (copy in 128- 419 P) .
Levy et al. "American Journal of Medical Electronics," Oct. - Dec.,
1964 pp. 242-248 (copy in 128-419D).
|
Primary Examiner: Kamm; William E.
Claims
We claim:
1. A method of fibrillating a heart which comprises the steps of
generating a multiple of low voltage electrical pulses, applying
the pulses to a pair of closely spaced electrodes and moving the
electrodes over the surface of the heart inducing arrhythmias
successively to a number of different fibers across the heart.
2. A method as claimed in claim 1 in which the pulses have a
potential of the order of 1 to 10 volts, last for periods of from 1
to 10 milliseconds, and are applied at intervals of about 11 to 50
milliseconds.
Description
This invention relates to the stimulation of tissues, such as
nerves and muscle fibers in human beings and in animals.
It is sometimes desirable to bring a heart into a state of
fibrillation for surgery to take place. Also, it may be desirable
to stimulate a bowel or bladder muscle, or a nerve.
According to the invention, a method of stimulating tissues
includes the step of applying a multiple of electrical pulses to a
number of different tissue fibers.
The electrical pulses may be of a low voltage, of the order of 1 to
10 volts. The pulses may last for periods of about 1 to 10
milliseconds. The pulses may be applied at intervals of about 10 to
50 milliseconds, and the energy input per pulse may be about 80
microwatt seconds.
In the following paragraphs the description will be directed
specifically to the stimulation of hearts. It must be understood,
however, that the method and the apparatus described may be
employed also for stimulating fibers such as nerves and other
muscles, e.g. smooth and skeletal muscles. The apparatus must
therefore not be understood as being limited to use in the
fibrillation of hearts.
Still according to the invention, a method of fibrillating a heart
muscle includes the step of applying a plurality of electrical
pulses to a number of different fibers of the heart.
The fibers may be disposed along the outer surfaces of the heart.
The current path through the heart muscle may be short relative to
the heart itself.
Further according to the invention, a method of fibrillating a
heart muscle includes the steps of wiping a pair of electrodes
across the surface of the heart and of applying successive
electrical pulses to the electrodes.
Yet further according to the invention, a method of fibrillating a
heart muscle includes the step of inducing arrhythmias in a number
of different fibers of the heart. The fibers may be disposed along
the heart surface.
Still further according to the invention, a tissue stimulator has a
plurality of electrodes, and means for applying a number of
electrical pulses to the electrodes.
The invention includes also a portable self-contained fibrillator,
powered by dry cell batteries.
The pulses may be provided by electronic circuitry, such as a
multivibrator, suitably energized. The circuitry may be energized
by a battery, and the battery and circuitry may be sealed in a
casing, thus providing a completely sealed unit independent of
power leads. It may be in the shape of a small pear, the electrodes
being provided at the small end. Alternatively, it may be of rod or
wand or probe shape. The battery may be housed in one end
constituting a handle.
The device may be provided with an automatic or attitude-sensitive
switch, e.g. by a mercury or gravity switch which switches off
automatically when the device is at rest or in a predetermined
attitude, but is energized immediately as its attitude changes.
Alternatively, the circuitry may be energized as soon as the
resistance across the electrodes falls below a predetermined
value.
The electrodes may be in the form of horseshoe formations disposed
in closely spaced parallel planes. The spacing between electrodes
may be of the order of 3 to 10 millimeters.
In applying electrical pulses to the heart muscle, current flow is
restricted substantially to the heart muscle only.
For the hearts of human beings, it has been found that the duration
of the electrical pulses advantageously are about 3 milliseconds.
The time interval between pulses conveniently matches the speed at
which wiping takes place so that successive pulses will be applied
to the adjacent zones of the heart muscle. Thus if the time
intervals between pulses are relatively short, the wiping rate may
be high. And if the time intervals between pulses are relatively
long, the wiping rate should be low.
The invention will now be described by way of example, with
reference to the accompanying drawings.
In the drawings:
FIG. 1 shows a circuit diagram of a first embodiment of the
invention having one type of pulse generator;
FIG. 2 shows a three-dimensional view of a fibrillator embodying
the circuitry of FIG. 1;
FIG. 3 shows a side elevation of another embodiment of rod or wand
shape;
FIG. 4 shows a section at IV--IV of FIG. 3; and
FIG. 5 shows a circuit diagram of the electrical circuitry of the
embodiment of FIGS. 3 and 4.
Referring to FIG. 1 of the drawings, reference numeral 10 refers
generally to circuitry for a fibrillator according to the
invention. It comprises a power supply 12 which is fixed or
removable, an attitude-sensitive switch 14, a pulse generator 16,
and electrodes 18, which may be extendable or fixed as desired. The
electrodes 18 are generally of horseshoe shape.
FIG. 2 shows one embodiment of fibrillator according to the
invention. It comprises an outer case 11 of synthetic plastic
material, in pear-shaped form. The various integers are indicated
diagrammatically and in block diagram form inside. The power supply
comprises batteries in a cavity which may be sealed by epoxy resin.
This seal may be translucent and may be broken to replace
batteries, whereafter resealing may take place again with epoxy
resin or some other suitable sealing agent.
Referring now to FIGS. 3 to 5 of the drawings, reference numeral
110 refers generally to a fibrillator according to another
embodiment of the invention. This fibrillator has a casing 111 of
substantially rod shape having a handle portion 112 and a curved
front portion 114 provided with a pair of electrodes 116 at its
end.
In the handle portion of the casing there is a cavity 118 for
housing a battery 120. The casing further has another cavity 122
for housing a multivibrator 124. This multivibrator is operatively
connected to the battery 120 and to the electrodes 116.
The casing is made of nylon and the battery and multivibrator are
sealed in. If the battery runs down, the seal may be broken and the
battery replaced and the casing resealed. Alternatively, the
battery may be rechargeable, connections being provided outside the
casing for connection to a suitable charger.
In use, the fibrillator will be sterilized as a whole before use.
When the electrodes are not connected via a patient's heart, the
circuit has only a very small battery drain. However, as soon as
the electrodes 116 are bridged by contacting a patient's heart or
by any other suitable fashion, transistor T1 switches on the
multivibrator T3--T3-and successive 3 millisecond 20 Hz. pulses
appear across the electrodes 116.
In order to induce fibrillation in a heart, the contacts are placed
in contact with the surface of the heart. Thereupon the electrodes
are displaced or wiped across the surface of the heart at a steady
rate. As soon as contact is made, the multivibrator generates the
voltage pulses. These pulses, because of the wiping action, are
applied to successive zones of the heart. These zones then go into
excitation which results in fibrillation of the heart.
In the second embodiment of the invention described, the casing is
stated to be of nylon. It will be understood, however, that the
casing may be made of any suitable material which can be
sterilized. This material may conveniently be a synthetic plastic
material. Another example of a synthetic plastic material which is
suitable, is polyvinylchloride.
It is an advantage of this invention that fibrillation can be
induced in a heart muscle with very low power inputs. This is
possible because the heart muscle fibers are fibrillated separately
in small groups. This is in contradistinction to conventional
fibrillation apparatus in which a massive pulse is administered to
electrodes placed at opposite ends of the heart, for fibrillating
all muscle fibers simultaneously.
The method according to the invention has the advantage that damage
to the heart is less than with conventional apparatus because of
the lower voltage used. Furthermore, the fibrillation induced in
accordance with the invention is "smoother" than that obtained in
conventional fashion.
The voltage pulses for inducing fibrillation into the hearts of
human beings, conveniently have the following characteristics:
Pulse potential 1 to 10 volts.
Pulse duration 1 to 10 milliseconds.
Time interval between pulses 10-50 milliseconds.
A fibrillator according to the invention can be made to provide
pulses having these characteristics.
In general broadly, therefore, a muscle or nerve stimulator
includes a portable self-contained sealed device. Such a device can
be so made and be of such materials that it can be sterilized as a
whole. It can also be used by a surgeon without any technical
assistance.
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