U.S. patent number 3,589,355 [Application Number 04/857,456] was granted by the patent office on 1971-06-29 for method for achieving reversible male sterilization.
Invention is credited to Hee Young Lee.
United States Patent |
3,589,355 |
Lee |
June 29, 1971 |
METHOD FOR ACHIEVING REVERSIBLE MALE STERILIZATION
Abstract
A method for obtaining reversible male sterilization by
occlusion of the vas deferens to block passage of the sperm
produced in the testes. A portion of the vas deferens is exposed by
a high midscrotal incision for the insertion of an intravasal plug.
The plug has a filiform thread attached to one of its ends and is
introduced into the vas by a straight needle from the testicular
side of the epididymal side of the vas with the filiform threads
allowed to extend through the wall of the vas at the epididymal
side. The filiform thread is then tied around the vas at the
epididymal side in order to hold the intravasal plug in place
thereby creating a mechanical obstruction to the passage of the
sperm.
Inventors: |
Lee; Hee Young (Seoul,
KS) |
Family
ID: |
25326028 |
Appl.
No.: |
04/857,456 |
Filed: |
September 12, 1969 |
Current U.S.
Class: |
128/843;
606/135 |
Current CPC
Class: |
A61F
6/22 (20130101) |
Current International
Class: |
A61F
6/00 (20060101); A61F 6/22 (20060101); A61b
019/00 () |
Field of
Search: |
;128/303,1 |
References Cited
[Referenced By]
U.S. Patent Documents
Other References
Lee--JOUR. OF THE KOREAN MEDICAL ASS'N., Vol. 10, No. 12--pp.
914--918, 1967 .
"Studies On Vasectomy--VII Experimental Studies On Reversible Vas
Occulsion By Intravasal Thread" MED. ASS'N. Vol. II, No. 9, Sept.
20, 1968.
|
Primary Examiner: Truluck; Dalton L.
Claims
What I claim:
1. A method for achieving reversible male sterilization by vas
occlusion comprising the steps of exposing a portion of the vas
deferens, inserting a physiologically inert elongated plug having
transverse dimensions of luminal size into the vasal lumen thereby
blocking passage of sperm, said plug having at least one
physiologically inert thread attached to its end thereof, fixing
said plug in said vasal lumen by tying said thread around the
epididymal side thereof and, restoring said vas deferens to its
original unexposed position.
2. A method as in claim 1 wherein said step of exposing a portion
of said vas deferens is accomplished by a high midscrotal incision
thereby exposing the nonciliated scrotal portion of said vas
deferens.
3. A method as in claim 1 wherein said plug consists of a
cylindrical plug of luminal diameter having at least one filiform
thread attached to one of its ends.
4. A method as in claim 3 wherein said plug is made of nonreactive
and nonabsorbable surgical nylon thread.
5. A method as in claim 1 wherein said plug is inserted into said
vasal lumen by means of a straight needle to which said mechanical
device is attached.
6. A method as in claim 1 wherein said plug is inserted into the
exposed vas deferens from the testes side to the epididymal
side.
7. A method as in claim 1 wherein said filiform thread is tied
around the circumference of the vas deferens at the epididymal
side.
8. In a method for reversing male sterilization achieved by vas
occlusion which comprises the steps of exposing a portion of the
vas deferens by a midscrotal incision, inserting into the vasal
lumen a physiologically inert plug of luminal diameter having at
least one physiologically inert thread attached to one of its ends
and extending through the wall of said vas deferens, fixing said
plug within said vasal lumen by tying said thread around said vas
deferens and restoring said vas deferens to its original unexposed
position and closing said scrotal incision, in which said
sterilization is reversed by exposing said portion of said vas
deferens containing said intravasal plug, cutting said thread tied
around said vas deferens thereby releasing said plug, removing said
plug from said vasal lumen by pulling said thread, introducing one
end of a splint thread into said previously occluded vasal lumen,
attaching said other end of said splint thread to the scrotal skin
and restoring said vas deferens to its original unexposed position
and closing said scrotal incision.
Description
This invention relates to a method for obtaining male
sterilization, more particularly, to a method for achieving
reversible male sterilization by the mechanical blocking of the
passage of sperm in the vas deferens with the passage of sperm
being readily restored upon removal of the mechanical blocking
device.
The conventional method for obtaining male sterilization is the
vasectomy which is generally performed on a permanent basis. The
permanency of the vasectomy and the present difficulty of restoring
fecundity has prevented this method of male sterilization from
being generally acceptable. attempts have been made therefore to
achieve reversible male sterilization by vas occlusion rather than
the vasectomy. A number of animal experiments have been carried out
along these lines using various means such as; and injection of
Biowax, the insertion of a piece of plastic material,
electrocoagulation, chemical cauterization, a nonoperative
vasoligature and the placement of nonreactive suture material. The
findings of these experiments were reported by Dr. H. Y. Lee in The
Journal of the Korean Medical Association, Vol. 10 No. 12:
914--918, 1967. It was reported there that the most satisfactory
method for reversible vas occlusion was the introduction of
nonreactive suture material. However, as stated in Dr. Lee's
report, the insertion of the nonreactive suture material caused an
undesirable dilatation of the vas due to an increased intravasal
pressure caused by deposition or stasis of continued sperm
production. This dilatation allowed sperm to pass through the
dilatated lumen of the vas even though the material was still in
place. Furthermore, difficulty was also encountered in restoring
the patency of the vasal lumen upon removal of the suture material
from the vas deferens thereby creating doubt as to the
reversibility of the method.
An object of the present invention is to remedy the deficiencies of
the prior attempts in obtaining male sterilization as outlined
above. In particular, an object of the invention is to provide a
method for achieving reversible male sterilization that will
successfully prevent passage of sperm from the testes through the
vas deferens. A further object of the invention is to provide a
method of obtaining reversible male sterilization by vas occlusion
that will block passage of sperm through a dilated vasal lumen. A
further object of the invention is to achieve reversible vas
occlusion that upon removal of the blocking device the patency of
the vasal lumen will be successfully restored.
The foregoing and other objects of the invention are obtained by a
method of inserting an intravasal plug having filiform threads
attached to one of its ends into the noncilated scrotal portion of
the vas. The ends of the filiform threads are extended through the
wall of the vas deferens around which they are tied to retain the
plug in place. The intravasal plug and filiform threads are made of
surgical nylon thread. The plug is inserted into the vasal lumen by
means of a straight needle to which the filiform nylon threads are
fixed, the needle is forced through the wall of the exposed vas
from the distal (testes) end to the proximal (epididymal) end of
the vas thereby permitting the plug to be pulled into the vasal
lumen by the filiform threads which are left extending through the
proximal end of the vas wall. The needle is thereafter disengaged
from the filiform threads which are then tied around the vas to
maintain the plug in place. The above described procedure is then
immediately carried out on the other side of the vas deferens and
after completion of that portion of the operation the scrotal
incision is closed.
For a better understanding of the invention, reference may be made
to the accompanying drawings, in which:
FIG. 1 is a prospective view of the intravasal plug and filiform
threads.
FIG. 1a is a prospective view of the intravasal plug attached to a
straight needle.
FIG. 2 is a view of the vas deferens exposed through the scrotal
incision.
FIG. 3 is a view of the intravasal thread attached to the straight
needle being inserted into the distal end of the vas.
FIG. 4 is a view of the intravasal thread being pulled into the vas
with the straight needle being forced through the wall of the vas
at the proximal end.
FIG. 5 is a view of the intravasal thread located within the vas
with the filiform nylon threads protruding through the wall of the
vas.
FIG. 6 is a view of the intravasal thread situated in its proper
position in the vas with the filiform threads tied around the
vas.
FIG. 7 is a view of the exposed vas deferens with the filiform
threads being cut in order to remove the plug.
FIG. 8 is a view of the intravasal thread being removed from the
vas deferens.
FIG. 1 illustrates an intravasal blocking device 10 which consists
of a plug portion 12 1 centimeter in length which is made of
surgical nylon thread of size No. 1 to No. 5 chromic catgut. It is
to be noted that the diameter of the plug is a function of the
inner diameter of the vasal lumen. Attached to the plug are two
filiform nylon threads 14 approximately 8 centimeters in length and
of size 6-0 chromic catgut. A number of different mechanical
devices were tested in attempting to obtain vas occlusion but it
was found that a physiologically inert material, such as nylon
thread, produced the best results. In order to insert the
intravasal plug into the vas deferens the filiform threads are
attached to a straight needle 16, as shown in FIG. 1a. The use of a
straight needle 16, as shown in FIG. 1a allows the intravasal plug
to be inserted into the vasal lumen without the incision of the
vas. The filiform nylon threads not only provide a means of
attaching the plug to the straight needle but also aid in retaining
the plug in its blocking position and further prevents the
dilatation of the vas as will be discussed below.
The first step in the method of inserting an intravasal plug is to
expose the vas deferens 18 through a high midscrotal incision
approximately 2 centimeters long as shown in FIG. 2. The vas 18 is
lifted above the surface of the scrotum by threads 20 which are
pulled by mosquito forceps 22. Once the vas has been properly
exposed the straight needle 16 to which the intravasal thread is
attached is inserted through the wall of the vas into the vasal
lumen 19. The initial insertion at point 24 of the vas is at the
distal (testes) side of the vas. The needle after entering the vas
at the distal end continues through the vasal lumen and is brought
through the wall of the vas at point 25 which is the proximal
(epididymal) side of the vas as shown in FIG. 4. Once the needle
protrudes through the wall of the vas it is continuously pulled
thereby drawing the plug 12 into the vasal lumen as shown in FIG.
5. With the plug 12 in place in the vasal lumen the straight needle
16 is severed from the ends of the filiform nylon threads which are
protruding through the wall of the vas. The filiform nylon threads
are then tied (FIG. 6) around the epididymal side of the vas in
order to hold the intravasal plug in place. Care should be taken
not to tie the filiform threads around the vas too tightly which
would choke the vas. Experiments have shown that if the vas is tied
too tightly it will be severely damaged and the continuity may not
be restored due to excessive ligation with the threads.
After the filiform nylon threads have been tied the same procedure
is immediately carried out on the other side of the vas deferens in
order to obtain complete blockage of the sperm passage. After
completion of the insertion of the intravasal thread in the other
vas deferens the scrotal incision is closed in the usual manner
with silk sutures by layers following clamping and tying of
bleeders as required.
The above method was used on three different groups of adult male
dogs. The three groups tested used different mechanical devices for
the vas occlusion. The first group consisted of nine dogs with
surgical nylon threads placed in the vas. The second group
consisted of nine dogs with surgical silk thread in the vas and the
third group comprised seven dogs which had a small piece of plastic
material inserted in the vas. 3 to 6 months after the insertion of
the intravasal thread, semen analysis showed that no sperm was
found in the ejaculates except in one case of faulty insertion of
the intravasal thread. These results are tabulated below.
##SPC1##
Vasography examinations also substantiated the success of the vasal
occlusion in that the lumen in the vas were completely occluded
without leakage under pressure 3 months after the thread had been
in place. Again, the only leakage that was found was with the
faulty insertion. The results of these tests are shown below:
##SPC2##
There were variations, however, of the amount of tissue reaction
found in the different groups. Histologic examinations indicated
that there was moderate to mild tissue reaction in the group that
used plastic as an intravasal blocking device. The group that used
silk thread showed only a mild reaction. The group that utilized
nylon as in intravasal blocking device showed minimal destruction
of the cells in the vas and very few abnormal inflammatory cells
were found. The results of the histologic tests are shown below:
##SPC3##
In order to remove the intravasal thread from the vas deferens the
vas is exposed in a similar manner as for the intravasal thread
insertion. The filiform nylon threads that are tied around the vas
are then cut, as shown in FIG. 7, and the intravasal plug 12 is
then removed by pulling the filiform nylon threads with a pair of
mosquito forceps (FIG. 8). The plug, upon being removed, passes
through the same opening that the straight needle made upon
insertion of the intravasal thread thereby eliminating the need for
the incision of the vas to remove the plug. Once the plug is
removed the patency of the vasal lumen is restored. In order to
prevent kinking of the vas after removal of the plug due to
extensive fibrotic contracture of surrounding tissues, a nylon
thread, 2-0 in size, is introduced into the previously occluded
vasal lumen as an internal splint with one end of the thread
connected to the scrotal skin. After the splint is introduced, the
incision is closed in the usual manner. The splint can normally be
removed on the 10th post operative day.
Three months after the removal of the intravasal plug, vasography
examination revealed that the patency of nine out of 11 vasa in
group 2 and four out of eight vasa in group 3 had returned almost
to normal. In eight of the dogs, two from group 1, two from group 2
and four from group 3, the intravasal thread was found to be too
large thereby causing tissue damage which resulted in vasal
strictures. The results of the vasography examination are
summarized below: ##SPC4##
Histological tests were also made 6 months after the placement of
the intravasal thread and from 1 to 3 months after removal with the
following results: ##SPC5##
This method has clearly achieved a proven reversibility not present
in the standard vasectomy. The relative permanency of a vasectomy,
even in light of some present day successful anastmosis of the vas
deferens, has been the greatest drawback to its acceptance and,
consequently, its failure to be the answer to the world's problem
of birth control. Furthermore, this method has also solved the
problems of previous attempts at vas occlusion (Study on
Vasectomy--VI Reversible Vas Occlusion Method on Experimental
Animals--Ibid.) in that the tying of the intravasal plug to the vas
deferens by the filiform threads has: 1. Prevented migration of the
internal plug upward in the vas, 2. stopped sperm escape by
preventing dilatation of the vasal lumen due to continued sperm
production and 3. avoids an incision of the vas for insertion
and/or removal. The method was reported in The Journal of the
Korean Medical Association Vol. II No. 9 Sept. 20, 1968 in an
article entitled "Studies on Vasectomy--VII Experimental Studies on
Reversible Vas Occlusion by Intravasal Thread."
The method may be carried out in other specific forms without
departing from the spirit or essential characteristics thereof. The
present described method is therefore to be considered in all
respects as illustrative and not restrictive, the scope of the
method being indicated by the appended claims rather than by the
foregoing description and all changes which come within the meaning
and range of equivalency of the claims are therefore intended to be
embraced therein.
* * * * *