U.S. patent number 3,552,591 [Application Number 04/880,483] was granted by the patent office on 1971-01-05 for pierceable closure for medicine bottles.
This patent grant is currently assigned to The West Company. Invention is credited to Hans Wimmer.
United States Patent |
3,552,591 |
Wimmer |
January 5, 1971 |
PIERCEABLE CLOSURE FOR MEDICINE BOTTLES
Abstract
A medicine bottle closure that can be stuck through, with a
flanged cap and with a sealing disc, which is made of at least two
different materials and which is anchored on the front face of the
bottle mouth, characterized in that a sealing disc 3 which seals
the flat front face 5 of the bottle mouth 1a, which is made with a
bevel-off 6 of its outer rim, consists of a layer, preferably of a
Teflon disc 8 or of a similar foil, which covers the bottle opening
and approximately half the bottleneck front-face 5 annular area
delimited by its outer and inner diameters, and consists of an
elastomeric gastight covering 7 which covers the bottle opening and
the entire front face, upon the middle zone of which disc is
applied the Teflon disc 8, and characterized in that this covering
disc 7 carries at its outer rim, as an anchorage, a ridge 7b that
fits the bevel 6 at the outer rim of the bottle mouth.
Inventors: |
Wimmer; Hans (Vicht,
DT) |
Assignee: |
The West Company (Phoenixville,
PA)
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Family
ID: |
5677999 |
Appl.
No.: |
04/880,483 |
Filed: |
December 10, 1969 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
Issue Date |
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779544 |
Nov 27, 1968 |
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Foreign Application Priority Data
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Nov 29, 1967 [DT] |
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P1,566,542 |
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Current U.S.
Class: |
215/247;
215/DIG.3 |
Current CPC
Class: |
B65D
51/002 (20130101); Y10S 215/03 (20130101) |
Current International
Class: |
B65D
51/00 (20060101); B65d 041/20 (); B65d 041/50 ();
B65d 041/22 () |
Field of
Search: |
;215/37,40 |
References Cited
[Referenced By]
U.S. Patent Documents
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3198368 |
August 1965 |
Kirkland et al. |
3424329 |
January 1969 |
Hershberg et al. |
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Primary Examiner: Hall; George T.
Parent Case Text
This application is a continuation of Ser. No. 779,544, filed Nov.
27, 1968, now abandoned.
Claims
I claim:
1. A medicine bottle closure that can be stuck through, with a
flanged cap and with a sealing disc which is made of at least two
different materials and which is anchored on the front face of the
bottle mouth, characterized in that a sealing disc 3 which seals
the flat front face 5 of the bottle mouth 1a, which is made with a
bevel-off 6 of its outer rim, consists of a layer, preferably of a
Teflon disc 8 or of a similar foil, which covers the bottle opening
and approximately half the bottleneck front-face 5 annular area
delimited by its outer and inner diameters, and consists of an
elastomeric gastight covering disc 7 which covers the bottle
opening and the entire front face, upon the middle zone of which
disc is applied the Teflon disc 8, and characterized in that this
covering disc 7 carries at its outer rim, as an anchorage, a ridge
7b that fits the bevel 6 at the outer rim of the bottle mouth.
2. A closure, which can be stuck through, for medicine bottles, in
accordance with claim 1, characterized in that the ridge 7b of the
covering disc 7 is dimensioned, and preferably made somewhat
wedge-shaped, so that after the flanging-in operation it is clamped
tightly in position.
3. A closure, which can be stuck through, for medicine bottles, in
accordance with claim 1, characterized in that the bevel angle of
the ridge 7b is flatter than the bevel 6 at the bottle mouth 1a,
and preferably the apex 7c of the ridge 7b in its undistorted state
projects somewhat over the remaining diameter of the covering disc
7.
4. A closure, which can be stuck through, for medicine bottles, in
accordance with claim 1, characterized in that the middle zone of
the covering disc 7, which carries the Teflon disc 8 or the like,
is surrounded by an annular groove 9.
5. A closure, which can be stuck through, for medicine bottles, in
accordance with claim 4, characterized in that the Teflon disc 8 is
drawn somewhat into the interior of the annular groove 9.
6. A process for the production of a sealing disc which consists of
at least two different materials and is in accordance with one of
the foregoing claims, and which forms a sealing disc which can be
stuck through, for the closure of medicine bottles, characterized
in that an elastic raw-rubber plate 7a, consisting of a rubber
mixture having in its freshly prepared state an adhesive effect, is
covered with a disc 8 of Teflon or similar foil having a roughened
surface, and while still in a fresh state it pressed upon or
applied upon it the said foil; and characterized in that in a
second operation the side of the raw-rubber plate to which the
Teflon foil is applied is laid in a press upon a circular cutting
tool 20 having a greater diameter than the inner diameter of an
annular groove 9 in the covering disc in its finished state, and is
pressed under relatively high pressure until the elastic raw-rubber
plate 7a is compressed to such an extent that the counterpressure
becomes so great that the cutting tool cuts through the Teflon foil
and the raw-rubber plate, after which, after relief of the
pressure, the reascending diameter-decreasing covering disc blank
7a, with its applied disc 8 of Teflon or the like, now projecting
over the inner diameter of the subsequent groove 9, is in a third
operation brought to the final peripheral form (al, 22 22) of the
sealing disc 3 and is subjected to a vulcanization operation,
whereby the projecting edges of the applied Teflon disc become bent
into the inner zone B delimited by an annular mold part f which
forms the groove 9 in the sealing disc 3.
7. A closure, which can be stuck through, for medicine bottles, in
accordance with claim 2, characterized in that the middle zone of
the covering disc 7, which carries the Teflon disc 8 or the like,
is surrounded by an annular groove 9.
8. A closure, which can be stuck through, for medicine bottles, in
accordance with claim 3, characterized in that the middle zone of
the covering disc 7, which carries the Teflon disc 8 or the like,
is surrounded by an annular groove 9.
9. A closure adapted to be held in place over the opening in a
container by a flanged cap comprising an elastomeric gastight
covering disc 7, a layer 8 of Teflon secured to the inner face of
said covering disc 7 confronting the container opening, said layer
8 being of a smaller diameter than the inner face of said covering
disc 7 so that it completely covers the opening in the container
and a portion of the container adjacent the opening therein and
means defining an annular groove in the inner face of said
elastomeric disc 7 adjacent the outer peripheral edge of said
Teflon layer 8, said groove overlying the portion of the container
adjacent the opening therein.
Description
The invention concerns a closure, for medicine bottles, which can
be stuck through, which has a flanged cap, and which has a sealing
disc made of at least two different materials and lying anchoring
on the front face of the bottle mouth; and the invention also
concerns a process for the production of this sealing disc,
consisting of at least two different materials, for a closure, for
medicine bottles, which can be stuck through.
There is already known a closure, for medicine bottles, which can
be stuck through and which has a sealing disc anchored relatively
to the bottle mouth. In this case the anchoring is formed of an
annular protruding bead of the bottle mouth which cooperates with a
corresponding annular groove provided in the sealing disc.
This form of construction has a number of drawbacks. In the first
place, providing the bottle mouth with such an annular bead is
expensive and also requires not inconsiderable manufacturing
tolerances, because glass bottles can not be produced with great
accuracy. Moreover with this type of anchorage for the sealing disc
on the bottle mouth it is not easily possible to house a second
cosealing part of the sealing disc. In the case of medicine bottles
it is however, often desired that the sealing disc shall have a
number of materials, of which the material of the side turned
toward the inside of the bottle should in particular be chemically
inert, while the outer part of the sealing disc should eliminate
certain disadvantages of the first-named part and/or should be less
expensive material, for forming the cheaper part of the sealing
disc. In addition, in the case of closures, for medicine bottles,
that can be stuck through, a radially acting anchorage of the
sealing disc is also needed, because the flanged cap often does not
hold the sealing disc sufficiently immovable in the said direction.
For certain medicaments there has proved to be particularly
suitable for the inner part of the sealing disc, which is turned
toward the medicament, a synthetic substance having the trademark
"Teflon," which is chemically inert with respect to many substances
and is obtainable commercially. On the other hand, however, perfect
sealing between a Teflon disc and the front face of a bottle mouth
is practically impossible, because relatively hard synthetic
substances such as Teflon are unable to adapt themselves properly
to unevennesses of the front face of glass bottles, so that the
content of the bottle creeps between the Teflon disc and the front
face of the bottle and emerges out of the bottle, and/or unsterile
air can get from the outside into the inside.
In accordance with an already known process for producing a sealing
disc made of two different materials, as a closure that can be
stuck through for medicine bottles, and in particular a process for
the application of a Teflon disc on a rubber sheet, it is known how
to stick these to one another, and to use hereby for this sticking
together an adhesive such as is ordinarily used for sticking rubber
to metals.
Such a process has the drawback that the adhesive, under the
relatively high temperature of the following vulcanization
operation, readily becomes resinified or hardened, through which it
is no longer possible to use a bottle closure consisting of such
sealing discs to meet the purpose of the invention, as a closure,
for medicine bottles, that can be stuck through to remove the
content of the bottle by means of a cannula, because for the
removal of the medicament the rubber disc together with the Teflon
disc have to be stuck through, and during this sticking through,
from the zone between the Teflon disc and the rubber disc residues
or portions of the adhesive used to stick the discs together may
get into the interior of the cannula, through which unforeseeable
injury may be done to patients.
The fundamental problem of the invention is to create for medicine
bottles a closure that can be stuck through, consisting of a
sealing disc that has a material that is chemically inert with
respect to many substances, and that is on occasion hard, and
consisting in particular of an inner part made of Teflon, whereby
there is obtained above all a reliable sealing and also sufficient
anchorage of the sealing disc, and furthermore the cost of making
such a medicine bottle and its closure comes out as cheap as
possible, and the problem includes creating a process for the
production of a sealing disc consisting of at least two different
materials, by which process, preferably, a Teflon disc, is
vulcanized on a rubber disc without it being necessary to use an
adhesive as a bonding means.
For solving this problem the invention proposes that, in the case
of a medicine bottle closure that can be stuck through, this
closure be made in such a way that a sealing disc which seals the
front face of the bottle mouth, which is made with a bevel-off of
its outer rim, shall consist of a layer, preferably a Teflon disc,
that covers the bottle opening and approximately half the
bottleneck front-face annular area delimited by its outer and inner
diameters, and shall consist of an elastomeric gastight covering
disc that covers the entire front face, upon the middle zone of
which disc is applied the Teflon disc, and the invention proposes
that this covering disc carry at its outer rim, as an anchorage, a
ridge that fits the bevel at the outer rim of the bottle mouth.
Through this it is obtained that the bottle contents can be sealed,
essentially by means of a chemically neutral material, namely a
synthetic substance of the Teflon type, and this relatively
expensive Teflon disc can be thin, and at the outer zone of the
bottle front face there is a covering disc that is gastight and
sufficiently elastic to complete the seal, and it can also, in
association with the ridge at its outer rim and the flanged cap,
form an anchorage.
A particularly favorable and reliable anchorage is obtained when
the ridge of the covering disc is made substantially wedge-shaped
is so dimensioned that it becomes clamped tightly after the
flanging-in of the cap.
In an advantageous way the middle zone of the covering disc, which
carries the Teflon disc or the like, can be surrounded by an
annular groove. This is not only of advantage during the production
in that it is possible to center the Teflon disc, which is to be
bonded to the covering disc, properly in a specified position, but
the Teflon disc, during its vulcanization on the covering disc, can
contract slightly inward, through which a better hold in the radial
direction is obtained.
The angle of bevel of the ridge of the covering disc can be flatter
than the bevel on the bottle mouth, so that the apex of the ridge,
in its unformed state, projects somewhat over the rest of the
diameter of the covering disc.
The Teflon disc can be bent a little inwardly into the annular
groove.
The problem of finding a process for the vulcanization of a Teflon
disc on a rubber plate, without having to resort to the aid of an
adhesive, was solved in that an elastic raw-rubber plate,
consisting of a rubber mixture having in its freshly prepared state
an adhesive effect, is covered with a disc of Teflon or the like
kind of foil having a roughened surface, and while still in a fresh
state it is pressed upon or applied upon this foil, and in that in
a second operation the side of the raw-rubber plate to which the
Teflon foil is applied is laid in a press upon an annular cutting
tool having a diameter greater than the inner diameter of an
annular groove of the covering disc in its finished state, and is
pressed under relatively high pressure until the elastic raw-rubber
plate is compressed to such an extent that the counterpressure
becomes so great that the cutting tool cuts through the Teflon foil
and the rubber plate under pressure, after which, after relief of
the pressure, the reascending diameter-decreasing covering disc
blank, with its applied disc of Teflon or the like projecting over
the inner diameter of the subsequent groove, is in a third
operation brought to the final peripheral form of the sealing disc
and is subjected to a vulcanization operation, whereby the
projecting edges of the applied Teflon disc become included in the
inner zone delimited by an annular former part forming the groove
of the sealing disc.
In the case of the rubber mixture, the expression "fresh state"
existing after its production means that state in which this rubber
mixture is as a rule still warm, and is in any event still
unpowdered and for that reason displays a sticky effect. With
certain materials the adhesive effect, among other things, can be
retained for a short time in the cold state while the just produced
rubber mixture is still unpowdered. In all cases the important
thing is that the rubber mixture, when after its production it is
still unpowdered, has its adhesive effect utilized.
The process of the invention affords the advantage that the
application of a roughened covering disc or foil, preferably made
of Teflon, enables this foil to stick tightly when it is applied
directly after the production of the raw-rubber plate, made from a
rubber mixture, while it is in a fresh state before being powdered,
through which it is unnecessary to use a sticky medium as an
adhesive, with all the aforesaid drawbacks. This application
process is made possible in that the rubber mixture, made in the
usual way in accordance with the specifications prescribed for
covering discs for sealing the medicaments concerned, while it is
still in a hot state and is unpowdered, has very great surface
adhesiveness, which vanishes after the vulcanization operation, but
persists however at that place covered by the application of the
roughened Teflon disc, because the presence of atmospheric oxygen
is necessary for eliminating the surface adhesiveness.
A further advantage of the process of the invention is that it
becomes possible for the foil to project somewhat over the
stamped-out round parts, so that these projecting edges can be bent
over, for better anchorage in the rubber part, by the pressure from
the press.
Further details of the invention are explained in more detail by
the aid of the drawings, where, in different scales:
FIG. 1 shows a vertical lengthwise section through the upper part
of a medicine bottle having a closure that can be stuck
through;
FIG. 2 shows to an enlarged scale a partial section through the
sealing;
FIG. 3 shows a cross section through the cutting tool in which is
situated the Teflon foil and the preshaped hardened raw-rubber
plate, with the Teflon disc applied to it, and this namely directly
prior to the cutting operation;
FIG. 4 shows the cutout disc blank, provided with the Teflon foil,
while it is being brought into the vulcanization mold, shown in
section; and
FIG. 5 shows in section the finished sealing disc, in the closed
vulcanization mold shown in section.
A medicine bottle 1 has a closure designated as a whole by 2. This
closure has a two-part sealing disc 3, which is fastened by means
of a flanged cap 4 to the bottle mouth designated as a whole by 1a.
The flanged cap 4 hereby is in known wise set in the middle zone of
a so-called tear-off tab 4a, and through tearing upward this tab
the middle region of the sealing disc 3 is exposed, so that it is
possible to stick through it, for example a hollow needle, a
cannula or the like, and then to draw off part or all of the
bottle's contents.
Medicine bottles 1 having such closures 2 are often used as
infusion flasks, whereby a hollow needle of fairly large diameter
is frequently stuck through the sealing disc 3.
The front face 5 of the bottle mount 1a is in known wise made flat,
and it is part of the invention that it has at its outer rim an
annular bevel 6. The sealing disc 3 consists of two parts: namely a
covering disc 7 and a thin Teflon disc 8. The covering disc 7 is
made of an elastomeric gastight material, of butyl rubber for
example. The middle zone of the covering disc, surrounded by an
annular groove 9, is covered by a Teflon disc 8, which is fastened
on by the process of the invention. Here the diameter of the Teflon
disc 8 and the inner diameter of the annular groove 9 are
respectively so that about half the bottleneck front-face annular
area 5 delimited by its outer and inner diameters is covered by the
Teflon disc 8.
As a material for the elastomeric gastight covering disc 7 butyl
rubber can be of good use. The Teflon disc 8 is near the annular
groove 9 in the covering disc 7 bent upward at its rim, as can be
clearly seen from FIG. 2. Through this the Teflon disc 8 has a
better hold in the radial direction also.
The aforesaid annular groove 9, whose shape is advantageous for
centering the raw-rubber plate 7a in the vulcanizing mold (FIGS. 4
and 5), has advantages even after the bottle is closed: it then
acts so to say as a labyrinth. If a perfect seal is practically
never obtained between the Teflon disc 8 and the front face 5 of
the bottle mouth, because Teflon or a similarly hard material is
unable to adapt itself sufficiently to unevennesses of the glass,
there still remains a labyrinthlike annular space between the
Teflon disc and the zone the covering disc 7 bears against. This
groove exerts a barrier effect particularly when there prevails in
it a pressure greater than prevails in the interior of the bottle,
for example in the case of evacuated bottles. With medicine bottles
1 that have to be sterilized again after being filled, an
above-normal pressure may be produced in the annular groove 9 and
be maintained there, for a certain time at least. This pressure
difference then prevents any slowly emerging contents of the bottle
from creeping between the bottle front face 5 and the Teflon disc
8, so as to then react chemically with the covering disc 7 and
exert a marked reaction on the contents of the bottle. Slight
quantities of the contents of the bottle that go radially outside
the Teflon disc 8 to enter into reaction with the covering disc 7
would for the greater part remain in the annular groove 9.
By means of the invention there is obtained a medicine bottle
having a closure 2 with which chemically neutral and on occasion
very hard synthetic substances, such as Teflon, which have
unfavorable characteristics as respects sealing in association with
glass, but which on the other hand have very desirable
characteristics, can be used for the sealing disc 3. Both the
manufacture of the medicine bottle 1 and also the manufacture of
the sealing disc and the flanging over hereby remain very
simple.
A substantial part of the invention is represented by the bevel 6
of the bottle mouth in cooperation with the ridge 7b at the outer
rim of the covering disc 7. The dimensions of the ridge are adapted
to the bevel 6 at the outer rim of the bottle mouth, and it is made
somewhat wedge-shaped with its apex turned downward, and it is
preferably dimensioned so that during the flanging-in of the
flanged cap 4 it becomes clamped tightly on the bottle mouth.
Through this there is obtained both a good supplementary sealing
with the covering disc 7, and also an anchoring of this covering
disc 7 and thus of the entire sealing disc 3. The aforesaid
clamping attachment of the sealing disc 7 is needed in particular
for processing the medicine bottles in completely automatic
flanging machines, because these flanging machines--on account of
the tolerances of the glass medicine bottle 1--do not always
operate with the same flanging pressure, so that the flanged cap 4
does not always receive the same flanging pressure, and thus the
pressure on the glass rim, over which the flanging takes place, is
not always uniform. It is true that the flanging pressure can be
adjusted so that a sufficient sealing of liquids is obtained;
however a sufficient sealing against gases can not be obtained. In
accordance with a further development of the invention, where the
bevel angle .alpha. (FIG. 2) of the ridge 7b is flatter or is much
flatter than the angle of the bevel 6 at the bottle mouth, the
result is that there is also good sealing between the outer rim 6
of the bottle and the ridge 7b even when the covering disc 7 is no
longer clamped very tightly against the front face 5 of the bottle
mouth 1a by the flanged cap 4. This reliable sealing in the region
of the ridge 7b is to a great extent independent of the production
tolerances. A good carrying along of the ridge 7b by the still open
flanged cap 4 while it is being put on is obtained when the apex 7c
of the ridge 7b, in its undeformed state, projects somewhat beyond
the remaining diameter of the covering disc
The sealing disc consisting of a Teflon foil fastened on a rubber
disc can be produced, without using any adhesive for sticking them
together, as follows:
A covering disc 7 is made from a specially composed rubber mixture,
which meets most of the requirement relatively to the contents to
be sealed in the bottle, and which has raw-rubber surface
adhesiveness, which vanishes after vulcanization at the places
exposed to the air and generally powdered, and which has the
property of adhering to a roughened Teflon foil. For this purpose
there is applied on such a raw-rubber plate 7a while it is still
hot, directly after it has been produced, a Teflon foil 8, with its
roughened surface pressed against the plate 7a.
In order to ensure that the Teflon disc is somewhat greater than
the inner diameter of the annular groove 9, disposed in the
covering disc when it is in its finished state, and in order later
on to be able to bend these projecting edges of the Teflon disc 8
in the direction of the annular groove 9, to make it possible to
obtain a better holding of the Teflon disc 8, the side of the
raw-rubber plate 7a upon which the Teflon foil 8a is applied is
laid on a not too sharp cutting tool 20 (FIG. 3), upon which tool
the round shape is stamped out under high pressure. The Teflon foil
8a in the first instant takes the pressure without the cutting tool
cutting into it. By means of the pressure on the raw-rubber plate
the rubber plate becomes compressed until the pressure has become
so great that the not too sharp circular knife 20 cuts into the
Teflon foil 8a (FIG. 3). The circular knife 20 has at this same
instant the counteraction of a pressed flat and somewhat radially
expanded raw-rubber plate, which after the pressure is relieved
ascends again and becomes smaller in diameter, while the
stamped-out Teflon disc 8 projects somewhat over the inner diameter
of the annular groove 9. After this, the covering disc 7, provided
with the Teflon disc 8, is put into a mold 21, 22, whereby the
projecting edges of the Teflon disc 8 become bent up by the forming
part f that makes the annular groove FIGS. 4 and 5).
After oxygen has reached the sides of the disc 7 not covered by the
Teflon disc 8, the great surface adhesiveness of the former
vanishes at the places coming into contact with air, and they may
if desired be powdered in knownwise.
The anchorage of the covering disc and on occasion an improvement
of its sealing action, is obtained by the ridge 7b of the
invention, which during the flanging-in becomes clamped laterally
against the bottle mouth. This squeezing-in of the pointed runout
of the ridge 7b is promoted in that the diameter of the medicine
bottle, like all glass objects, has relatively large manufacturing
tolerances, so that the flanged cap 4 leaves a certain clearance
between it and the outer contour of the bottle mouth 1a, into which
clearance parts of the ridge 7b become drawn during the flanging
operation, and at the end of the flanging operation they are
clamped there with a sealing effect. The clamping attachment is
important particularly when a hollow needle is stuck with great
force through the sealing disc 3, or when such an operation is done
repeatedly by a cannula. It is advantageous in the latter case that
the covering disc 7 consists of an elastomeric material that closes
up again after the cannula is removed from the stuck through
hole.
In a way that is of itself known the covering disc 3 can have a
thinning 12 of its wall, to facilitate the sticking-in.
It should also be mentioned that the sealing disc blank 7, 8 put
into the open mold 21, 22 is dimensioned as respects its part 7,
which is for example made of butyl rubber, in such a way that this
material, when the mold parts 21, 22 are closed, fills the
remaining hollow space, as is shown by a comparison of FIGS. 4 and
5.
* * * * *