U.S. patent number 3,890,972 [Application Number 05/400,573] was granted by the patent office on 1975-06-24 for syringe injector with pop-top cap.
This patent grant is currently assigned to Abbott Laboratories. Invention is credited to Glenn Lee Beall, Wendell Evert Standley.
United States Patent |
3,890,972 |
Standley , et al. |
June 24, 1975 |
Syringe injector with pop-top cap
Abstract
A syringe assembly including a vial in which a unit dose of an
injectable medicament can be prepackaged and an injector portion
comprising a solid post molded along a substantial portion of the
cannula to provide support and a pair of longitudinally extending
wings projecting from the hub of the injector. A threaded stem
extends from the post for receiving the thread stopper of the vial,
the threads on the stem being intermittent. A cap for covering the
threaded stem prior to use includes a flange which mates with
finger grips on the wings whereby the cap can be removed by
pressure applied to the wings. Possible contact with the threaded
stem or cannula which could contaminate the system is thereby
minimized.
Inventors: |
Standley; Wendell Evert (Lake
Forest, IL), Beall; Glenn Lee (Gurnee, IL) |
Assignee: |
Abbott Laboratories (North
Chicago, IL)
|
Family
ID: |
23584140 |
Appl.
No.: |
05/400,573 |
Filed: |
September 25, 1973 |
Current U.S.
Class: |
604/110; 604/192;
604/203; 206/365; 604/227 |
Current CPC
Class: |
A61M
5/2429 (20130101) |
Current International
Class: |
A61M
5/24 (20060101); A61m 005/24 (); B65d 083/10 () |
Field of
Search: |
;128/220,218D,218N,221,215,272,218R,218DA,218P ;206/43,63.2R,63.4
;215/38,41,47,53,DIG.3 ;85/1L |
References Cited
[Referenced By]
U.S. Patent Documents
Foreign Patent Documents
|
|
|
|
|
|
|
1,376,918 |
|
Sep 1964 |
|
FR |
|
1,074,827 |
|
Feb 1960 |
|
DT |
|
Primary Examiner: Gaudet; Richard A.
Assistant Examiner: McGowan; J. C.
Attorney, Agent or Firm: Niblack; Robert L. Fato; Gildo E.
Hamilton; Neil E.
Claims
What is claimed is:
1. A medicament injector for receiving a vial having a stopper
therein,
said injector comprising an integral holder including a solid post
having a double-ended cannula molded therein, the post extending
along a substantial portion of the length of the cannula,
said post having a hub on the distal end thereof from which one end
of the cannula projects and a stem on the proximal end for
receiving the stopper of the vial, the other end of the cannula
projecting from the stem;
a laterally extending base interconnecting the post and the
hub;
a pair of opposed, longitudinally extending wings projecting from
the base toward the stem and terminating in finger grips, said
finger grips including angularly projecting portions extending from
said wings in a slanted manner;
a stop member extending from the post at the proximal end thereof;
and
a cap member defined by a tubular body portion having an open end
and a closed end, the open end being defined by a base portion from
which extends an obtusely slanted flange mating with the angularly
projecting portion of the finger grips of said wings, said base
portion adapted to engage the stop on the post and to be
frictionally held on the post whereby said cap can be removed by
applying pressure to the extending wings.
2. The medicament injector of claim 1 wherein said stop is circular
and said stem is threaded.
3. The medicament injector of claim 2 wherein the base portion of
said cap is adapted to engage the circular stop on the post and has
internal gripping means.
4. The medicament injector of claim 3 wherein said post is of
cruciform shape and the threads are interrupted to facilitate
removal of the holder from the mold in the molding process.
5. The medicament injector of claim 4 including a stiffener rib
molded into the holder and extending from the hub along the base
and along at least a portion of the wings.
6. The medicament injector of claim 5 including a notch formed in
the hub adjacent the base of the holder to facilitate destruction
of the injector after use to thereby prevent reuse thereof.
7. The medicament injector of claim 1 wherein the post includes at
least one opening intermediate the ends thereof, the opening
exposing the cannula whereby said cannula can be supported
intermediate its ends as well as at the ends during the molding
procedure.
Description
BACKGROUND OF THE INVENTION
Injectable medicaments are oftentimes packaged in ampules or other
containers from which the injectable fluid is removed as required.
For example, at point of use, the ampule is opened, the appropriate
amount of injectable fluid is drawn into a syringe and thereafter
injected. Prepackaged, injectable medicaments in unit dose form are
much more convenient and more importantly, can be injected quickly
as needed without the need for removing the medicament from the
ampule or other container and loading a syringe with the fluid.
U.S. Pat. Nos. 3,376,886 and 3,378,008, issued Apr. 9 and Apr. 16,
1968 respectively, disclose a medicament injector with attached
vial and comprising a vial which contains the injectable fluid and
which can be filled with the desired injectable fluid, sealed and
then stored for use, and an injector for receiving the vial.
Likewise, U.S. Pat. Nos. 2,524,362, issued Oct. 3, 1950 and No.
2,568,346, issued Sept. 18, 1951 disclose syringe assemblies
employing a separate vial or ampule, however, the injector portions
of such devices are somewhat difficult to manufacture. With such
devices, the injector body is molded and the cannula is inserted in
place through an opening molded in the hub and affixed thereto by
means of an adhesive such as epoxy. Additionally, the cannula is
supported along only a small portion of its length and
consequently, is subject to bending, loosening, coming off center,
and the like. Additionally, with some of these devices, since
threaded portions are included in the injector, the molded part is
difficult to remove from the mold which results in much lower
molding rates than optimum.
SUMMARY OF THE INVENTION
The syringe assembly of the present invention includes a vial in
which a unit dose of an injectable medicament can be prepackaged
and an injector portion comprising a solid post molded along a
substantial length of the cannula to thereby provide good support
along almost its entire length. A pair of longitudinally extending
wings project from the hub of the injector, with finger grips being
formed on the end of the wings. A threaded stem extends from the
post for receiving the threaded stopper of the vial, the short,
proximal end of the double ended cannula extending therefrom, the
threads on the stem being intermittent to facilitate removal of the
part from the mold. Finger grips for grasping the injector extend
angularly from the wings and contact and similarly extending flange
of the cap which covers the threaded stem and proximal end of the
cannula. To remove the cap prior to use, pressure is applied to the
wings to forceably remove the cap from the post and expose the
threaded stem and cannula for receiving the vial. Consequently, the
cap need not be touched, thereby minimizing the possibility of the
fingers contacting the cannula prior to use. Accordingly, since the
injector of the present invention can be injection molded using
insert molding techniques, since no core pins are required, and
since the molded part can be easily removed from the mold; the
injector can be manufactured rapidly and economically.
BRIEF DESCRIPTION OF THE DRAWING
Other features and advantages will be apparent from the following
specification and drawings in which:
FIG. 1 is a perspective view of the injector of the present
invention;
FIG. 2 is a side view, partially in cross-section of the injector
illustrated in FIG. 1;
FIG. 3 is an end view as viewed along the line 3--3 of FIG. 1;
FIG. 4 is a cross-sectional view taken along the line 4--4 of FIG.
2;
FIG. 5 is an end view as viewed along the line 5--5 of FIG. 2;
FIG. 6 is a fragmentary view of a portion of the injector
illustrating a modification thereof;
FIG. 7 is a side view, partially in section, of the syringe
assembly of the present invention including a vial and injector;
and
FIG. 8 is a perspective view of a vial cap for sealing the vial
after filling.
DETAILED DESCRIPTION
Referring to the drawings, FIG. 7 illustrates a syringe assembly 10
of the present invention including a vial portion 11 and an
injector portion 12. The vial 11 comprises a cylindrical body 13
having an open end 14 and a closed end 15. A puncturable stopper 16
is inserted in the open end 14 of the vial 11 and is moveable
within the vial 11, the stopper 16 having internal threads 17
formed therein. A diaphragm 18 closes the end of the stopper
opposite the threads and receives the cannula as hereinafter
described. The vial 11 can be filled with a liquid medicament on
conventional filling machines and the stopper 16 inserted in the
open end 14 of the vial 11. Thereafter the vial 11 and medicament
therein can be sterilized and a cover 19 inserted in the open end
14 of the vial 11 adjacent the stopper 16 to maintain sterility of
the stopper 16 and vial 11 during handling and transportation.
Preferably, the vial 11 is made of glass. When filled, sealed and
sterilized, the vial 11 comprises a self-contained package which
can be readily stored and conveniently used in conjunction with the
injector 12 as hereinafter described.
Referring to the drawings, particularly FIGS. 1 through 5 and 7
thereof, the injector portion 12 comprises an integral holder 30
having a double-ended cannula 31 molded therein. As best seen in
FIGS. 1 and 2, the holder 30 comprises a longitudinally extending
post 32 having a hub 33 on the distal end 25 thereof and a threaded
stem 38 on the proximal end 26 thereof. The hub 33 is of a tapered
configuration and includes a base portion 34 of larger diameter
than the luer taper portion 35 extending therefrom. The hub base
portion 34 is adapted to receive a needle covering sheath (not
shown) while the forward tapered portion 35 is adapted to receive a
corresponding female fitting. The post 32, as best seen in FIGS. 1
and 4, includes a crusiform shaped body 36 with a circular stop 37
at the proximal end 26 thereof from which the threaded stem 38
projects. The use of a crusiform shape for the body 36 results in
maximum strength with the use of a minimum amount of material but
other shapes, such as circular or square, can be used. As
illustrated, the threaded stem 38 includes interrupted threads 39.
The distal end 26 of the post 32 includes a laterally extending
base 40 interconnecting the post 32 and the hub 33. A pair of
longitudinally extending wings 41 project from the base 40 and
terminate in finger grips 42. The finger grips 42 include angularly
projecting portions 43 which slant from wings 41 and from which
extend laterally projecting shoulders 44. To provide additional
strength, a stiffener rib 45 can be molded into the holder 30
extending from the hub 33 along the base 40 and along a portion of
the wings 41.
The injector 12 can be fabricated using conventional insert molding
techniques. The cannula 31 is centered in a mold and the holder 30
is molded thereabout by means of injection molding methods. While
various plastic materials can be used, polypropylene is preferred.
In the holder 30 of the present invention, the cannula 31 is
supported along almost its entire length and therefore cannot get
off center. With many prior art devices, the cannula is held at
only one place, such as a hub and as a result, due to cooling in
the molding process, handling, and the like, the cannula can be
displaced from a central position. Hence, during use, the cannula
may not properly pierce the stopper 16 in the vial 11. As can be
seen, by employing insert molding techniques, an integral holder 30
having a cannula 31 molded directly therein results. With prior art
devices, a relatively large diameter opening is molded in the hub
of the holder, the cannula is inserted therein and fixed in place
by epoxy adhesive. Consequently, additional steps are required and
further, there is a possibility that the cannula will not be
centrally located. Likewise, by employing an interrupted thread
design as illustrated, after the holder 30 is molded, the molded
part can readily be removed from the mold simply by separation of
the mold. This avoids the necessity of having to unscrew the mold
from the threaded stem after it has been molded. As can be seen in
the drawings, the distal end 25 of the cannula 31 extends beyond
the hub 33 a sufficient distance to facilitate insertion of the
cannula 31 into a vein of a patient while the proximal end 26
extends a short distance from the threaded stem 38 sufficient to
permit piercing of the diaphragm 18 in the vial stopper 16. For
very thin or very long cannulas, to permit adequate support of the
cannula 31 in the mold during the molding procedure, openings 47
can be molded directly in the post 32 intermediate the ends thereof
as illustrated in FIG. 6. The cannula 31 can thereby be supported
intermediate its ends as well as at the ends during the molding
procedure. If desired, to prevent reuse of the injector 12, the
distal end 25 of the cannula 31 and post 32 can be broken from the
holder 30 prior to discarding. To facilitate destruction of the
injector 12 before discarding, a notch 49 can be formed in the base
34 of the hub 33 adjacent the base 40 of the holder 30 as
illustrated in FIGS. 2 and 5. The hub 33 can then simply be bent to
cause a fracture of the hub 33 at the notch 49.
To maintain sterility of the threaded stem 38 and the extending
cannula as well as to prevent damage prior to use, a cap 50 is
positioned over the threaded stem 38 and cannula 31 as illustrated
in FIG. 2. The cap 50 comprises a tubular body portion 51 having an
open end 52 and a closed end 53, the open end 52 being defined by a
base portion 54 from which extends an obtusely slanted flange 55
adapted to mate with the angularly projecting portion 43 of the
finger grips 42 of the holder 30. To assist in retaining the cap 50
in place, nibs or rings 56 can be formed on the inside of base
portion 54, which nibs 56 act to grip the stop 37 on the post 32 of
the holder 30. To remove the cap 50 prior to use, the extending
wings 41 of the holder 30 are grasped between the thumb and index
fingers and pressure applied whereby the angularly projecting
portion 43 of the finger grips 42 will press against the mating
flange 55 of the cap 50 whereby the cap will slip from the stop 37.
As is apparent, in removing the cap 50, the fingers are prevented
from contacting the threaded stem 38 or cannula 31 and thereby
contaminating the system.
In using the syringe assembly 10, the cap 50 is removed from the
injector 12 as previously described. A pre-filled vial 11
containing the medicament desired is selected and the cover 19 is
removed. The vial 11 is then inserted on the post 32 of the
injector 12, engaging the threaded stem 38 of the post 32 with the
threads 17 in the stopper 16 of the vial 11. Referring to FIG. 2,
it can be seen that the threaded stem 38 has a cone shaped section
59 located between the interrupted threads 39 and the end of the
cannula 31 which projects from the threaded stem 38. The cone
shaped section 59 has two functions: (1) to help guide the vial 11
and the vial stopper 16 into position, and (2) to at least
partially seal the stopper 18 to the injector 12 at the point
before the cannula 31 pierces the stopper diaphragm 18. This allows
the injector 12 and vial 11 to be assembled in a sterile condition
without actually piercing the stopper diaphragm 18. As the mating
threads are engaged, proximal end 26 of the cannula 31 will pierce
the diaphragm 18 of the vial stopper 16 as illustrated in FIG. 7 to
provide communication between the cannula bore and the interior of
the vial 11. Since the vial stopper 16 will be restrained by the
stop 37 on the post 32, pressure on the vial 11 will result in the
stopper 16 moving rearwardly within the vial 11 causing the
injectable medicament to flow through the cannula 31 whereby the
medicament can be injected. Likewise, pressure can be relieved by
withdrawing the vial 11 so that aspiration will result to either
determine whether proper entry into a vein has been made or for
drawing other liquids into the vial 11.
As is apparent, the syringe assembly of the present invention can
be easily and economically manufactured. Further, the vial 11 and
injector 12 can be assembled together with minimum possibility of
contamination. Additionally, the injector portions of prior syringe
assemblies include two concentric rings. The central ring or
cylinder surrounds the cannula with the outer cylinder forming the
barrel of the injector. Such a structure dictates that the overall
size of the injector must be larger than the vial. In contrast, the
structure of the holder 30 is basically rectangular in cross
section as shown in FIGS. 3, 4 and 5. In the longitudinal
direction, the injector 12 or holder 30 is larger than the vial 11.
However, in the short direction of the rectangle, the holder 30
need not be larger than the vial 11. In use, this means that the
injector 12 and vial 11 assembly can be positioned at a smaller
angle in relationship to the puncture site, thereby facilitating
entry into a vein and minimizing the possibility of accidental
puncturing of the vein wall.
* * * * *