U.S. patent application number 17/448134 was filed with the patent office on 2022-01-06 for medication administration status management device, method, and non-transitory recording medium that records program.
The applicant listed for this patent is OMRON HEALTHCARE Co., Ltd.. Invention is credited to Mizuki FURUTA, Asa HIRASAWA, Kensuke IBATA, Tomoya ISHIDA, Hideyuki KOBAYASHI, Hiroshi OGAWA, Tamio UEDA.
Application Number | 20220005571 17/448134 |
Document ID | / |
Family ID | 1000005897810 |
Filed Date | 2022-01-06 |
United States Patent
Application |
20220005571 |
Kind Code |
A1 |
OGAWA; Hiroshi ; et
al. |
January 6, 2022 |
MEDICATION ADMINISTRATION STATUS MANAGEMENT DEVICE, METHOD, AND
NON-TRANSITORY RECORDING MEDIUM THAT RECORDS PROGRAM
Abstract
To ensure further accurate management of a status of medication
administration, one aspect of the present invention acquires
declaration information regarding the medication administration of
a user, acquires biological information of the user and causes a
storage medium to store the biological information, calculates a
degree of dispersion of the biological information acquired in a
target period based on the biological information stored in the
storage medium, determines reliability of the declaration
information regarding the medication administration acquired in the
target period based on the degree of dispersion of the biological
information, and outputs information representing a determination
result of the reliability.
Inventors: |
OGAWA; Hiroshi; (Kyoto,
JP) ; HIRASAWA; Asa; (Kyoto, JP) ; UEDA;
Tamio; (Kyoto, JP) ; IBATA; Kensuke; (Kyoto,
JP) ; ISHIDA; Tomoya; (Kyoto, JP) ; KOBAYASHI;
Hideyuki; (Kyoto, JP) ; FURUTA; Mizuki;
(Kyoto, JP) |
|
Applicant: |
Name |
City |
State |
Country |
Type |
OMRON HEALTHCARE Co., Ltd. |
Kyoto |
|
JP |
|
|
Family ID: |
1000005897810 |
Appl. No.: |
17/448134 |
Filed: |
September 20, 2021 |
Related U.S. Patent Documents
|
|
|
|
|
|
Application
Number |
Filing Date |
Patent Number |
|
|
PCT/JP2020/008797 |
Mar 3, 2020 |
|
|
|
17448134 |
|
|
|
|
Current U.S.
Class: |
1/1 |
Current CPC
Class: |
A61B 5/4833 20130101;
G16H 10/60 20180101; G16H 20/10 20180101 |
International
Class: |
G16H 20/10 20060101
G16H020/10; A61B 5/00 20060101 A61B005/00; G16H 10/60 20060101
G16H010/60 |
Foreign Application Data
Date |
Code |
Application Number |
Mar 25, 2019 |
JP |
2019-057045 |
Claims
1. A medication administration status management device comprising:
a processor configured to: acquire declaration information
regarding medication administration of a user; acquire biological
information of the user and cause a storage medium to store the
biological information; calculate a degree of dispersion of the
biological information acquired in a target period based on the
biological information stored in the storage medium; determine
reliability of the declaration information regarding the medication
administration acquired in the target period based on the degree of
dispersion of the biological information; and output information
representing a determination result of the reliability, wherein the
processor determines whether the degree of dispersion of the
biological information or a degree of divergence of an actually
measured value with respect to a predicted value of the biological
information that is calculated is higher than or lower than a
threshold value; and when the processor determines that the degree
of dispersion or the degree of divergence of the biological
information is higher than the threshold value, the processor
generates a message prompting the medication administration or
correct declaration for the medication administration, and outputs
the message to at least one of a terminal of the user and a
terminal of a person involved having a prescribed relationship with
the user.
2. A medication administration status management device comprising:
a processor configured to: acquire declaration information
regarding medication administration of a user and cause a storage
medium to store the declaration information; acquire biological
information of the user and cause the storage medium to store the
biological information in a state in which the biological
information is associable with the declaration information having a
corresponding acquisition timing; calculate a predicted value of
the biological information in a second period in which the
biological information is a monitoring target based on the
declaration information and the biological information in a first
period in which a medication administration status is known and
stored in the storage medium; calculate a degree of divergence of
an actually measured value of the biological information acquired
during the second period with respect to the calculated predicted
value of the biological information; determine reliability of the
declaration information regarding the medication administration in
a third period that affects a change in the biological information
in the second period based on the calculated degree of divergence,
the third period being prior to the second period; and output
information representing a determination result of the
reliability.
3. The medication administration status management device according
to claim 1, wherein the processor is further configured to:
calculate a medication administration ratio representing a ratio of
a number of times that the medication is declared to be
administered to a total number of declarations for the medication
administration in the declaration target period of the medication
administration based on the declaration information regarding the
medication administration; and set the threshold value such that a
lower medication administration ratio causes a higher value
according to the calculated medication administration ratio.
4. The medication administration status management device according
to claim 1, wherein the processor is further configured to:
determine whether there is a missing of a declaration regarding the
medication administration in the declaration information based on
the declaration information regarding the medication
administration; and when the missing of the declaration is
determined as present, the processor is further configured to
determine that the declaration regarding the medication
administration needs to be prompted to the user.
5. The medication administration status management device according
to claim 4, wherein when the processor determines that the
declaration regarding the medication administration needs to be
prompted to the user, processor is further configured to output
information prompting the declaration regarding the medication
administration to the user; and the processor is further configured
to determine presence or absence of a response from the user to a
presentation of the information prompting the declaration regarding
the medication administration, and when the response is determined
as absent, the processor is further configured to regard that the
declaration regarding the medication administration is not made and
omit a declaration process of the reliability of the declaration
information.
6. The medication administration status management device according
to claim 1, wherein the processor is further configured to:
calculate a medication administration ratio representing a ratio of
a number of times that the medication is declared to be
administered to a total number of declarations for the medication
administration in a declaration target period of the medication
administration based on the declaration information regarding the
medication administration; and correct the medication
administration ratio based on a determination result of the
reliability of the declaration information.
7. The medication administration status management device according
to claim 1, wherein the processor is further configured to transmit
the information representing the determination result of the
reliability to a terminal used by a medication administrator for
the user.
8. The medication administration status management device according
to claim 1, wherein the processor is further configured to cause
the storage medium to store the determination result of the
reliability, and update the determination result of the reliability
stored in the storage medium each time a new reliability
determination result is obtained.
9. A medication administration status management method performed
by an information processing device including a processor and a
storage medium, the method comprising: acquiring declaration
information regarding medication administration of a user and
causing the storage medium to store the declaration information by
the information processing device; acquiring biological information
of the user and causing the storage medium to store the biological
information by the information processing device; calculating a
degree of dispersion of the biological information acquired in a
target period based on the biological information stored in the
storage medium; determining reliability of the declaration
information regarding the medication administration acquired in the
target period based on the calculated degree of dispersion of the
biological information; and outputting information representing a
determination result of the reliability, wherein the determining
the reliability determines whether the degree of dispersion of the
biological information or a degree of divergence of an actually
measured value with respect to a predicted value of the biological
information calculated by the calculating is higher than or lower
than a threshold value; and when the determining the reliability
determines that the degree of dispersion or the degree of
divergence of the biological information is higher than the
threshold value, the outputting generates a message prompting the
medication administration or correct declaration for the medication
administration, and the outputting outputs the message to at least
one of a terminal of the user and a terminal of a person involved
having a prescribed relationship with the user.
10. A medication administration status management method performed
by an information processing device including a processor and a
storage medium, the method comprising: acquiring declaration
information regarding medication administration of a user and
causing the storage medium to store the declaration information by
the information processing device; acquiring biological information
of the user and causing the storage medium to store the biological
information by the information processing device; calculating a
predicted value of the biological information in a second period in
which the biological information is a monitoring target based on
the declaration information and the biological information in a
first period in which a medication administration status is known
and stored in the storage medium by the medication administration
status management device; calculating a degree of divergence of an
actually measured value of the biological information acquired
during the second period with respect to the calculated predicted
value of the biological information by the medication
administration status management device; determining reliability of
the declaration information regarding the medication administration
in a third period that affects a change in the biological
information in the second period based on the calculated degree of
divergence by the medication administration status management
device, the third period being prior to the second period; and
outputting information representing a determination result of the
reliability by the medication administration status management
device.
11. A non-transitory recording medium that records a program for
causing the processor provided with the medication administration
status management device according to claim 1 to execute processes
in the medication administration status management device.
12. A non-transitory recording medium that records a program for
causing the processor provided with the medication administration
status management device according to claim 2 to execute processes
in the medication administration status management device.
Description
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is the U.S. national stage application
filed pursuant to 35 U.S.C. 365(c) and 120 as a continuation of
International Patent Application No. PCT/JP2020/008797, filed Mar.
3, 2020, which application claims priority to Japanese Patent
Application No. 2019-057045, filed Mar. 25, 2019, which
applications are incorporated herein by reference in their
entireties.
TECHNICAL FIELD
[0002] Embodiments of the present invention relate to a medication
administration status management device, a method, and a
non-transitory recording medium that records a program used to
manage, for example, a status of medication administration by a
user.
BACKGROUND ART
[0003] Treatment with medication is one method of treating
diseases. It is extremely important in the medication treatment to
comply with administration of a medication prescribed by a
physician to obtain an intended therapeutic effect.
[0004] Thus, for example, there has been proposed the following
technology. A patient inputs declaration information representing a
medication administration status, such as whether medication
administration has been performed, using a mobile information
terminal, such as a smartphone. Based on this declaration
information, medication administration adherence information
representing a status of compliance with the medication
administration is generated. This information can be displayed on a
terminal of the patient or a terminal of a physician or a
pharmacist (for example, see Patent Document 1).
[0005] The use of this technology allows a medication
administrator, such as a physician and a pharmacist, to accurately
grasp a relationship between the medication administration of the
patient and the therapeutic effect and therefore is significantly
effective. Another is effect is that the patient becomes motivated
to continue taking their medication.
CITATION LIST
Patent Literature
[0006] Patent Document 1: JP 2018-151993 A
SUMMARY OF INVENTION
Technical Problem
[0007] On the other hand, among patients who undergo a medication
administration treatment while spending daily life at home,
although not administering a medication as described in a
prescription, some patients make a false declaration that the
medication was administered due to a reason, such as low interest
in complying with the medication administration and general
busyness. In such circumstances, the above-described prior art does
not examine, for example, whether the medication is truly
administered for the medication administration declaration by the
patient, and therefore a medication administrator, such as a
physician and a pharmacist, possibly cannot correctly determine the
relationship between the medication administration and the
therapeutic effect. This possibly leads to an erroneous medication
judgment, such as an increase in dosage and a change of a medicine
type, which is considerably undesirable.
[0008] The present invention has been made focusing on the
circumstances, and attempts to provide a technology that provides
information with which a status of medication administration can be
more accurately managed.
Solution to Problem
[0009] To solve the above problems, one aspect of a medication
administration status management device or a method according to
the present invention acquires declaration information regarding
medication administration of a user, acquires biological
information of the user and causes a storage medium to store the
biological information, calculates a degree of dispersion of the
biological information acquired in a target period based on the
biological information stored in the storage medium, determines
reliability of the declaration information regarding the medication
administration acquired in the target period based on the degree of
dispersion of the biological information, and outputs information
representing a determination result of the reliability.
Advantageous Effects of Invention
[0010] According to an aspect of the present invention, the
following effects are provided. That is, in general, the degree of
dispersion of the biological information is associated with a
compliance status of the medication administration. For example,
observing the degree of dispersion of blood pressure values
regularly measured every day in the target period for one week, the
degrees of dispersion of blood pressure values of patients who
comply with the medication administration tend to be small, and
conversely, the degrees of dispersion of blood pressure values of
patients who do not comply with the medication administration tend
to be large. Thus, as in the first aspect according to the present
invention, calculating the degree of dispersion of measured values
of the biological information, such as a blood pressure, in the
target period, determining the reliability of medication
administration declaration based on this degree of dispersion, and
output it allow, for example, a physician or a pharmacist to
accurately infer a status of the medication administration of the
user as a patient, and to diagnose an effect brought by the
medication.
[0011] That is, according to one aspect of the present invention, a
technology that provides information with which the status of the
medication administration can be more accurately managed can be
provided.
BRIEF DESCRIPTION OF DRAWINGS
[0012] FIG. 1 is a functional block diagram illustrating one
application example of a medication administration status
management device according to the present invention.
[0013] FIG. 2 is a diagram illustrating an overall configuration of
a system including a mobile information terminal as a first
embodiment of the medication administration status management
device according to the present invention.
[0014] FIG. 3 is a diagram illustrating an example of a hardware
configuration of the mobile information terminal illustrated in
FIG. 2.
[0015] FIG. 4 is a diagram illustrating an example of a software
configuration of the mobile information terminal illustrated in
FIG. 2.
[0016] FIG. 5 is a flowchart depicting a procedure and a process
content of a medication administration status management process by
the mobile information terminal illustrated in FIG. 4.
[0017] FIG. 6 is a flowchart depicting an example of a procedure
and a process content of a medication administration declaration
reliability determination process in the flowchart depicted in FIG.
5.
[0018] FIG. 7 is a diagram illustrating an example of a software
configuration of a mobile information terminal as a second
embodiment of a medication administration status management device
according to the present invention.
[0019] FIG. 8 is a flowchart depicting a procedure and a process
content of a medication administration status management process by
the mobile information terminal illustrated in FIG. 7.
[0020] FIG. 9 is a flowchart depicting an example of a procedure
and a process content of a medication administration declaration
reliability determination process in the flowchart depicted in FIG.
8.
[0021] FIG. 10 is a diagram illustrating an example of an input
template displayed on a user terminal when a declaration for
medication administration is input.
DESCRIPTION OF EMBODIMENTS
[0022] Embodiments according to one aspect of the present invention
will be described below based on the drawings. However, the
embodiments described below are merely illustrative of the present
invention in all respects.
Application Example
[0023] First, one application example of a medication
administration status management device according to the present
invention will be described. FIG. 1 is a diagram for describing
this one application example, a user terminal is denoted as UT and
a blood pressure monitor is denoted as BP.
Configuration Example
(1) Blood Pressure Monitor
[0024] The blood pressure monitor BP is a stationary or an upper
arm-attached blood pressure monitor that measures a blood pressure,
for example, by oscillometric method, and has a function of
transmitting measurement data of the blood pressure to the user
terminal UT using a wireless communication circuit employing a
short-range wireless data communication standard, such as Bluetooth
(registered trademark). Note that a wrist type or a wristwatch
blood pressure monitor may be used as the blood pressure monitor,
in addition to the stationary or upper arm-attached blood pressure
monitor in which a cuff is wound around an upper arm for
measurement. Using the wristwatch blood pressure monitor allows
automatically measuring a blood pressure intermittently or at a
preset time.
(2) User Terminal UT
[0025] The user terminal UT is configured of a mobile information
terminal, such as a smartphone, possessed by a user as a patient.
As functions according to one application example of the present
invention, the user terminal UT includes an input/display device
100, a blood pressure measurement data acquisition unit 200, a
dispersion degree calculation unit 300, a medication administration
declaration information acquisition unit 400, a medication
administration declaration reliability determination unit 500, a
determination information output unit 600, and a wireless
communication circuit 700.
[0026] Among these, the blood pressure measurement data acquisition
unit 200, the dispersion degree calculation unit 300, the
medication administration declaration information acquisition unit
400, the medication administration declaration reliability
determination unit 500, and the determination information output
unit 600 are achieved, for example, by causing a hardware processor
to execute a program.
[0027] The input/display device 100 is a tablet device in which a
capacitive or pressure sensitive type input detection sheet is
disposed on a liquid crystal or an organic EL screen, and outputs
medication administration declaration information input by an
operation of the user to the medication administration declaration
information acquisition unit 400. The medication administration
declaration information acquisition unit 400 takes in the
medication administration declaration information output from the
input/display device 100 and causes a memory in the user terminal
UT to store the information.
[0028] The wireless communication circuit 700 has multiple wireless
interface functions that communicate with respective wide area
mobile communication network, wireless local area network (LAN),
and Bluetooth (registered trademark). In this example, the wireless
communication circuit 700 is used to receive the measurement data
of the blood pressure transmitted from the blood pressure monitor
BP, and to transmit determination information of reliability of the
medication administration declaration information input by the user
to a terminal of a medication administrator, such as a physician
and a pharmacist.
[0029] The blood pressure measurement data acquisition unit 200
takes in the measurement data of the blood pressure received by the
wireless communication circuit 700 and causes the memory in the
user terminal UT to store it.
[0030] The dispersion degree calculation unit 300 reads the
measurement data of the blood pressure measured in a preset target
period (for example, one day or one week) from the memory, and
calculates a degree of dispersion (for example, a degree of
variation in measured values or a degree of variation in changes in
the measured value).
[0031] The medication administration declaration information
acquisition unit 400 takes in information declaring the status of
the medication administration in the medication administration
period input by the user in the input/display device 100 and causes
the memory in the user terminal UT to store the information.
[0032] The medication administration declaration reliability
determination unit 500 determines the reliability of the medication
administration declaration information input by the user based on
the degree of dispersion of the blood pressure measurement data
calculated by the dispersion degree calculation unit 300. This
reliability is determined, for example, based on the number of
times (timing) of the medication administration in one day and the
content designated by prescription information. The prescription
information is acquired from, for example, the terminal of the
physician or the pharmacist or an EMS server in a hospital and
stored in a storage unit 800.
[0033] For example, the determination information output unit 600
generates a notification message to report a determination result
of the reliability of the medication administration declaration
information for the medication administrator, such as the physician
and the pharmacist, based on the determination result of the
reliability of the medication administration declaration
information, and causes the wireless communication circuit 700 to
transmit the notification message to the terminal of the physician
or the pharmacist. For example, the determination information
output unit 600 also has a function of generating a notification
message demanding the declaration for the medication administration
of the user and displaying it on the input/display device 100. Note
that the determination information output unit 600 may have a
function of generating a communication message for a family member,
for example, when the reliability is lower than a threshold value
as a result of the determination of the reliability of the
medication administration declaration information and transmitting
the communication message from the wireless communication circuit
700.
Actions and Effects
[0034] With the configuration described above, in the user terminal
UT, the blood pressure measurement data acquisition unit 200
acquires the blood pressure measurement data of the user together
with the medication administration declaration information of the
user in the medication administration period by the medication
administration declaration information acquisition unit 400. Based
on the acquired blood pressure measurement data, a blood pressure
value of the blood pressure measurement data or the degree of
dispersion of the changes in the period on a daily or weekly basis
is calculated. Based on the calculated degree of dispersion of the
blood pressure values, the medication administration declaration
reliability determination unit 500 determines the reliability of
the medication administration declaration information of the user
in the same period, and the determination information output unit
600 outputs the determination information representing the
determination result.
[0035] Here, generally, the degree of dispersion of the blood
pressure values is associated with a compliance status of the
medication administration. For example, observing the degree of
dispersion of blood pressure values regularly measured every day in
the target period for one week, the degrees of dispersion of blood
pressure values of patients who comply with the medication
administration tend to be small, and conversely, the degrees of
dispersion of blood pressure values of patients who do not comply
with the medication administration tend to be large.
[0036] Thus, as described above, determining the reliability of the
medication administration declaration based on the degree of
dispersion of the blood pressure values in the target period and
transmitting the result to the terminal of the medication
administrator allow the medication administrator, such as the
physician and the pharmacist, to accurately infer the status of the
medication administration of the user as the patient and to
diagnose the effect of the medication.
[0037] In addition, in the medication administration status
management device according to the present invention, the following
application example is conceivable.
[0038] For example, a medication administration status management
device includes a declaration information acquisition unit, a
biological information acquisition unit, a prediction unit, a
calculation unit, a reliability determination unit, and an output
unit. The declaration information acquisition unit acquires
declaration information regarding medication administration of a
user and causes a storage medium to store the declaration
information. The biological information acquisition unit acquires
biological information of the user and causes the storage medium to
store the biological information in a state in which the biological
information is associable with the declaration information having a
corresponding acquisition timing. The prediction unit calculates a
predicted value of the biological information in a second period in
which the biological information is a monitoring target based on
the declaration information and the biological information in a
first period in which a medication administration status is known
and stored in the storage medium. The calculation unit calculates a
degree of divergence of an actually measured value of the
biological information acquired during the second period with
respect to the calculated predicted value of the biological
information. The reliability determination unit determines
reliability of the declaration information regarding the medication
administration in a third period that affects a change in the
biological information in the second period based on the calculated
degree of divergence. The third period is prior to the second
period. The output unit outputs information representing a
determination result of the reliability.
[0039] According to the configuration, the following effects are
provided. That is, generally, a change in the actually measured
value of the biological information of the user who complies with
the medication administration with respect to the predicted value
is considered as small. Therefore, the degree of divergence between
the predicted value of the biological information in the second
period (the monitoring period of the biological information), which
is predicted from the biological information and the declaration
information of the medication administration measured in the first
period (a prediction reference period) in which the medication
administration status is known, and the actually measured value of
the biological information actually measured during the second
period tends to be small. In contrast, in a case where the user who
does not comply with the medication administration declares for
medication administration as if the user complied with the
medication administration, it is inferred that the degree of
divergence between the predicted value of the biological
information and the actually measured value of the biological
information actually measured in the second period in which the
medical efficacy should appear becomes large.
[0040] Thus, as in this application example, based on the
biological information and the declaration information of the
medication administration obtained in the past first period in
which the medication administration status is known, the value of
the biological information in the second period as the monitoring
period of the biological information is predicted. Based on the
degree of divergence of the actually measured value of the
biological information actually measured with respect to this
predicted value, the reliability of the declaration information of
the medication administration in the third period, which is prior
to the second period, that affects the change in the biological
information in the second period is determined and the result is
output. This allows the medication administrator, such as the
physician and the pharmacist, to further accurately grasping the
status of the medication administration in the medication
administration period of the user as the patient.
[0041] For example, in the medication administration status
management device, the reliability determination unit determines
whether a degree of dispersion of the biological information or a
degree of divergence of an actually measured value with respect to
a predicted value of the biological information calculated by the
calculation unit is higher than or lower than a threshold value.
When the reliability determination unit determines that the degree
of dispersion or the degree of divergence of the biological
information is higher than the threshold value, the output unit
generates a message prompting the medication administration or
correct declaration for the medication administration. The output
unit outputs the message to at least one of a terminal of the user
and a terminal of a person involved having a prescribed
relationship with the user.
[0042] According to the configuration, in the case where the degree
of dispersion or the degree of divergence of the biological
information is determined as higher than the threshold value, the
message prompting the correct medication administration or
declaration for medication administration is generated and is
output to the terminal of the user or the terminal of the person
involved, such as a family member, having the prescribed
relationship with the user. This allows further reliably
enlightening the user so as to perform the correct medication
administration or declaration for medication administration.
[0043] For example, in the medication administration status
management device, the reliability determination unit calculates a
medication administration ratio representing a ratio of a number of
times that the medication is declared to be administered to a total
number of declarations for the medication administration in the
declaration target period of the medication administration based on
the declaration information regarding the medication
administration. The reliability determination unit sets the
threshold value such that a lower medication administration ratio
causes a higher value according to the calculated medication
administration ratio.
[0044] According to such a configuration, the threshold value is
set such that the threshold value becomes higher as the medication
administration ratio lowers. This allows further accurate
determination when the user declares "taken" although the user does
not actually take the medicine.
[0045] For example, in the medication administration status
management device, the reliability determination unit determines
whether there is a missing declaration regarding the medication
administration in the declaration information based on the
declaration information regarding the medication administration.
When the missing of the declaration is determined as present, the
reliability determination unit determines that the declaration
regarding the medication administration needs to be prompted to the
user.
[0046] According to the configuration, when the declaration
information input by the user is determined as including a missing,
it is determined that the declaration regarding the medication
administration needs to be prompted to the user. This allows
prompting the user to declare the medication administration without
omission before the reliability of the declaration information is
determined.
[0047] For example, when it is determined that the declaration
regarding the medication administration needs to be prompted to the
user, the medication administration status management device
outputs information prompting the declaration regarding the
medication administration to the user. The medication
administration status management device determines presence or
absence of a response from the user to a presentation of the
information prompting the declaration regarding the medication
administration. When the response is determined as absent, the
medication administration status management device regards that the
declaration regarding the medication administration is not made and
omits a declaration process of the reliability of the declaration
information.
[0048] According to the configuration, when the user does not input
the declaration for the medication administration in response to
the demand for the declaration for medication administration, it is
regarded that the declaration regarding the medication
administration is not made, and the determination process of the
reliability of the declaration information is not performed. This
allows reducing a process load on the device in a case where the
effective declaration information is not input.
[0049] For example, the medication administration status management
device further includes a medication administration ratio
calculation unit and a correction unit. The medication
administration ratio calculation unit calculates a medication
administration ratio representing a ratio of a number of times that
the medication is declared to be administered to a total number of
declarations for the medication administration in a declaration
target period of the medication administration based on the
declaration information regarding the medication administration.
The correction unit that corrects the medication administration
ratio based on a determination result of the reliability of the
declaration information by the reliability determination unit.
[0050] According to the configuration, the medication
administration ratio is calculated from the declaration information
of the medication administration. Therefore, for example,
transmission of this medication administration ratio to the
terminal of the medication administrator allows the medication
administrator to grasp the medication administration status of the
user by the value, the medication administration ratio. Moreover,
since the medication administration ratio is corrected based on the
reliability of the declaration information, the accurate medication
administration ratio where an declaration error and a false
declaration by the user have been considered can be recognized.
[0051] For example, in the medication administration status
management device, the output unit transmits the information
representing the determination result of the reliability to a
terminal used by a medication administrator for the user.
[0052] According to the configuration, for example, the medication
administrator, such as the physician and the pharmacist, can
automatically acquire the reliability of the declaration
information of the medication administration of the user, and this
can be useful for, for example, examination of a necessity to
change the prescription.
[0053] For example, in the medication administration status
management device, the reliability determination unit causes the
storage medium to store the obtained determination result of the
reliability. The reliability determination unit updates the
determination result of the reliability stored in the storage
medium each time a new reliability determination result is
obtained.
[0054] According to the configuration, the reliability of the
medication administration declaration determined in the
determination target period of the medication administration
declaration reliability is tentatively continued until the
reliability of the next medication administration declaration is
determined, that is, held for a period after the determination
target period to the present.
First Embodiment
Configuration Example
(1) System
[0055] FIG. 2 is a diagram illustrating an overall configuration of
the system including a medication administration status management
device according to the first embodiment of the present invention,
the user terminal as the medication administration status
management device is denoted as UT and the blood pressure monitor
as a biological information measurement device is denoted as
BP.
[0056] The blood pressure monitor BP is a blood pressure monitor,
for example, of a type in which a cuff is wound around an upper arm
of the user to measure a blood pressure value by oscillometric
method, and has a function of transmitting the measurement data of
the blood pressure to the user terminal UT over a short-range
wireless network, such as Bluetooth (registered trademark). A wrist
type or a wristwatch blood pressure monitor may be used as the
blood pressure monitor BP, in addition to the type in which the
cuff is wound around the upper arm for measurement. Among these,
the wristwatch blood pressure monitor can employ, as a measurement
method, an oscillometric method or a pulse transit time (PTT), and
automatically measure a blood pressure intermittently or at a
preset time. Note that, the blood pressure monitor BP can be
connected to the user terminal UT via, for example, any wireless
network including a wireless Local Area Network (LAN) and a signal
cable.
[0057] The user terminal UT can transmit data over a network NW
between a medication-administrator terminal MT used by the
medication administrator, such as the physician and the pharmacist,
and a family terminal FT used by the family member of the user. The
network NW is formed of, for example, a wide area network that uses
the Internet as a core, and an access network for connecting the
terminals to this wide area network.
(2) User Terminal UT
(2-1) Hardware Configuration
[0058] FIG. 3 is a block diagram illustrating an example of the
hardware configuration of the user terminal UT.
The user terminal UT is formed of a mobile information terminal,
such as a smartphone or a tablet terminal, possessed by, for
example, the user as the patient. The user terminal UT includes a
hardware processor 1 (hereinafter also simply referred to as a
CPU), such as a Central Process Unit (CPU), and a memory 2, an
input/display device 3, and a wireless communication circuit 4 are
connected to the CPU 1 via a bus.
[0059] For example, the memory 2 uses a combination of a
non-volatile memory, such as a Solid State Drive (SSD), that can
write and read at any time and a volatile memory, such as a Random
Access Memory (RAM), as a storage medium, and includes a program
storage area and a data storage area in the storage area. The
program storage area is used to store a middleware program that
functions as an Operation System (OS) and various application
programs. The data storage area is used to store various kinds of
data used to determine the reliability of the medication
administration declaration information.
[0060] The input/display device 3 is configured of, for example, a
tablet device in which a capacitive or pressure sensitive input
sheet is disposed on a display using a liquid crystal or an organic
EL and is used to input operation information by the user and
display the display information.
[0061] The wireless communication circuit 4 has multiple wireless
interface functions that wirelessly communicate with each of a
short-range wireless network, such as Bluetooth (registered
trademark), a local wireless network within a home or within an
enterprise, such as a wireless LAN, and a public mobile
communication network provided by a carrier. Among them, the
wireless communication circuit 4 receives the measurement data of
the blood pressure from the blood pressure monitor BP over the
short-range wireless network and performs data transmission with
the medication-administrator terminal MT over the local wireless
network or the public mobile communication network. Note that a
control of, for example, a wireless communication protocol is
usually performed in the CPU 1, but may be performed in the
wireless communication circuit 4. Note that 41 denotes an
antenna.
(2-2) Software Configuration
[0062] FIG. 4 is a block diagram illustrating a software
configuration of the user terminal UT in association with the
hardware configuration illustrated in FIG. 3.
[0063] The data storage area in the memory 2 is provided with a
medication administration declaration information storage unit 21,
a blood pressure measurement data storage unit 22, and a
prescription information storage unit 23. The medication
administration declaration information storage unit 21 stores input
template data used when the user inputs the declaration information
of the medication administration. The medication administration
declaration information storage unit 21 stores the declaration
information of the medication administration input with the
input/display device 3 by the user in accordance with the input
template data associated with information representing date and
time of the medication administration. The blood pressure
measurement data storage unit 22 stores the measurement data of the
blood pressure transmitted from the blood pressure monitor BP
associated with information representing date and time of the
measurement. The prescription information storage unit 23 stores
the prescription information of the user downloaded from the
terminal MT of the medication administrator, such as the physician
and the pharmacist, or an Electronic Medical Records (EMR)
server.
[0064] The CPU 1 includes a medication administration declaration
information acquisition unit 11, a blood pressure measurement data
acquisition unit 12, a dispersion degree calculation unit 13, a
medication administration declaration reliability determination
unit 14, and a determination information output unit 15 as process
function units according to the first embodiment. These control
units 11 to 15 are all achieved by causing the CPU 1 to execute an
application program stored in the program memory area in the memory
2.
[0065] The medication administration declaration information
acquisition unit 11 is activated by, for example, an input request
operation of the medication administration declaration by the user,
reads the input template data from the medication administration
declaration information storage unit 21, and causes the
input/display device 3 to display the input template data. Then,
the medication administration declaration information acquisition
unit 11 performs a process that receives the declaration
information of the medication administration input by the user in
accordance with a guidance of the input template data from the
input/display device 3, associates the declaration information with
the information representing the date and time of the medication
administration, and causes the medication administration
declaration information storage unit 21 to store the declaration
information. Note that the medication administration declaration
information acquisition unit 11 may, for example, be activated in
response to a response operation by the user to the message (a
reminder) prompting the declaration for the medication
administration.
[0066] The blood pressure measurement data acquisition unit 12 is
activated by a data transmission request from the blood pressure
monitor BP, and performs a process that associates the blood
pressure measurement data transmitted from the blood pressure
monitor BP and received by the wireless communication circuit 4
with the information representing the date and time of the
measurement and causes the blood pressure measurement data storage
unit 22 to store the blood pressure measurement data.
[0067] The dispersion degree calculation unit 13 reads, from the
blood pressure measurement data storage unit 22, the measurement
data of the blood pressure including the date and time of the
measurement in the determination target period each time the preset
determination target period (for example, on a daily or weekly
basis) passes. The dispersion degree calculation unit 13 performs a
process that calculates the degree of dispersion of the read blood
pressure measurement data, for example, the degree of variation of
the blood pressure measurement values or the changes.
[0068] The medication administration declaration reliability
determination unit 14 performs a process that determines the
reliability of the medication administration declaration
information in the same period input by the user based on the
calculation result of the degree of dispersion of the blood
pressure measurement data obtained by the dispersion degree
calculation unit 13. An example of the reliability determination
will be described later.
[0069] The determination information output unit 15 performs a
process that generates notification information for notifying the
medication administrator, the family member of the user, or the
user himself/herself of the determination result of the reliability
of the medication administration declaration information by the
medication administration declaration reliability determination
unit 14, and transmits the notification information to the
medication-administrator terminal MT or the terminal FT of the
family member, or causes the input/display device 3 to display the
notification information.
Operation Example
[0070] Next, operations of the user terminal UT configured as
described above will be described. FIG. 5 and FIG. 6 are flowcharts
exemplifying the operations.
(1) Acquisition of Medication Administration Declaration
Information
[0071] The user terminal UT monitors the operation of the input
request for the medication administration declaration information
in a standby state in step S10. In this state, assume that the user
performed a tap operation on an icon to which, for example, a
medication administration declaration function is assigned in the
input/display device 3. Then, the user terminal UT activates the
medication administration declaration information acquisition unit
11, and first reads the input template data from the medication
administration declaration information storage unit 21 and causes
the input/display device 3 to display the input template data in
step S11.
[0072] In this state, for example, when the user inputs the
presence or absence of the medication administration after
breakfast, after lunch, and after dinner on the day in accordance
with the input template, the input information representing the
presence or absence of the medication administration at each meal
is received from the input/display device 3 and the medication
administration declaration information storage unit 21 is caused to
store the information. At this time, information representing date
and time of the declaration is given to each piece of the
information representing the presence or absence of the medication
administration.
[0073] For example, some users possibly input the declaration for
the medication administration for one day at once after dinner,
before going to bed, or the next day or later. In such a case, in a
case where the date and time of the input is directly regarded as
the date and time of the medication administration, the date and
time of the declared medication administration differs from the
true date and time of the medication administration.
[0074] Therefore, for example, as illustrated in FIG. 10, the input
template includes checkboxes 31a, 32a, and 33a for inputting the
presence or absence of the medication administration, and input
fields 31b, 32b, and 33b for the time of the medication
administration corresponding to each of after breakfast, after
lunch, and after dinner described above about a date and time 30
that is not input. Then, the medication administration declaration
information storage unit 21 is caused to store the information
representing the presence or absence of the medication
administration and the information representing the medication
administration time input to the corresponding checkboxes 31a, 32a,
and 33a and input fields 31b, 32b, and 33b for each of the
breakfast, the lunch, and the dinner as the medication
administration declaration information. Note that the input
template illustrated in FIG. 10 as an example displays a medicine
type 34 target for the medication administration. By displaying the
medicine type, for example, the user who administers multiple types
of medicines can input the medication administration declaration
information without a mistake for each medicine type.
[0075] After that, each time the user performs the input request
operation of the medication administration declaration, under the
control by the medication administration declaration information
acquisition unit 11, the user terminal UT performs a process that
receives the above-described medication administration declaration
information and causes the medication administration declaration
information storage unit 21 to store it.
(2) Acquisition of Blood Pressure Measurement Data
[0076] In the standby state, the user terminal UT monitors the
transmission request for the blood pressure measurement data from
the blood pressure monitor BP in step S12. In this state, when
receiving the transmission request for the blood pressure
measurement data from the blood pressure monitor BP, the user
terminal UT activates the blood pressure measurement data
acquisition unit 12, takes in the blood pressure measurement data
transmitted from the blood pressure monitor BP and received by the
wireless communication circuit 4 from the wireless communication
circuit 4, and causes the blood pressure measurement data storage
unit 22 to store the measurement blood pressure data in step S13.
At this time, since the information representing the date and time
of the measurement is transmitted along with the blood pressure
measurement data, the user terminal UT associates the blood
pressure measurement data with the date and time of the measurement
and causes the blood pressure measurement data storage unit 22 to
store the data.
[0077] Thereafter, each time the user terminal UT receives the
transmission request from the blood pressure monitor BP, the user
terminal UT performs reception and storage processes of the
above-described blood pressure measurement data under the control
by the blood pressure measurement data acquisition unit 12.
(3) Calculation of Degree of Dispersion of Blood Pressure
Measurement Data
[0078] The user terminal UT monitors a determination request for
medication administration declaration reliability while performing
the acquisition process of the medication administration
declaration information and the acquisition process of the blood
pressure measurement data in step S14. In this state, when the
determination request is generated from a soft timer in the CPU 1,
for example, at the end of the determination target period, for
example, one day or one week, the user terminal UT activates the
dispersion degree calculation unit 13. Then, under the control by
the dispersion degree calculation unit 13, in step S15, the blood
pressure measurement data including the date and time of the
measurement in the most recent determination target period is read
from the blood pressure measurement data storage unit 22 and the
degree of dispersion of the blood pressure measurement data is
calculated based on each piece of the read blood pressure
measurement data.
[0079] The degree of dispersion can be obtained, for example, as a
standard deviation or a dispersion of all compression period blood
pressure values measured in the determination target period, a
difference between the highest value and the lowest value among all
of the compression period blood pressure values, the number of or a
proportion of compression period blood pressure values exceeding an
allowable blood pressure variation range that is set with the
average value of all of the compression period blood pressure
values as the center.
[0080] Note that in the above example, the case in which the
determination request occurs at the end of the determination target
period has been described. However, no such limitation is intended.
For example, the determination request may be transmitted from the
terminal MT of the medication administrator, such as the physician
or the pharmacist, or the terminal FT of the family member, and at
the time point of receiving the determination request, the degree
of dispersion of the blood pressure measurement values in a certain
period before this time point (for example, one day or one week)
may be calculated.
(4) Determination of Medication Administration Declaration
Reliability
[0081] When the degree of dispersion of the blood pressure
measurement data is calculated, the user terminal UT then activates
the medication administration declaration reliability determination
unit 14. Then, under the control by the medication administration
declaration reliability determination unit 14, the reliability of
the medication administration declaration information corresponding
to the determination target period stored in the medication
administration declaration information storage unit 21 is
determined in step S16.
[0082] FIG. 6 is a flowchart depicting an example of a process
procedure and a process content of the determination process of the
medication administration declaration reliability. The medication
administration declaration reliability determination unit 14 first
reads the medication administration declaration information
corresponding to the determination target period from the
medication administration declaration information storage unit 21
and determines whether any medication administration declaration
has been made based on the medication administration declaration
information in step S161. In other words, the presence or absence
of a missing in the medication administration declaration is
determined.
[0083] For example, in a case where the determination target period
is one day, insofar as the number of times that the medication
administration declaration is not made is at least one time among
the number of medication administrations designated in the
prescription information stored in the prescription information
storage unit 23, the medication administration declaration is
determined as absent in the day. For example, in a case where the
determination target period is one week, when the number of days in
which the medication administration declaration is not made at all
is one day or more or the prescribed number of days or more, it is
determined that the medication administration declaration is absent
in this week. In the case where the medication administration
declaration is determined as absent, the medication administration
declaration reliability determination unit 14 regards that the
medication administration declaration information is out of the
determination target of the medication administration declaration
reliability, determines that "a demand to the user for the
medication administration declaration is required," and passes the
determination result to the determination information output unit
15 in step S162.
[0084] On the other hand, when the medication administration
declaration is determined as present in the step S161, the
medication administration declaration reliability determination
unit 14 next determines whether the degree of dispersion of the
blood pressure measurement data calculated by the dispersion degree
calculation unit 13 is greater than or equal to a threshold value
in step S163. As a result of the determination, in the case of the
degree of dispersion being greater than or equal to the threshold
value, the medication administration declaration reliability
determination unit 14 determines that the reliability of the
medication administration declaration information in the
determination target period is "low" in step S164. In contrast, in
the case of the degree of dispersion being less than the threshold
value, the medication administration declaration reliability
determination unit 14 determines that the reliability of the
medication administration declaration information in the
determination target period is "high" in step S165.
[0085] Note that the information of the medication administration
declaration includes information representing the presence or
absence of the declaration, that is, both of the declaration of
"taken" and the declaration of "not taken." Therefore, the
medication administration declaration reliability determination
unit 14 calculates the medication administration ratio (the number
of declarations of "taken"/the total number of declarations of
medication administration (the number of declarations of
"taken"+the number of declarations of "not taken")) and sets a
determination threshold value of the degree of dispersion for each
calculated medication administration ratio. That is, the
determination threshold value is set such that the threshold value
becomes high as the medication administration ratio lowers. In this
way, more accurate determination can be made.
[0086] That is, in a case where the medicine is not actually
administered, the degree of dispersion of blood pressure values
increases. However, with the threshold value not adjusted, in a
case where the correct declaration "not taken" is made, since the
dispersion is large, the reliability is determined as "low" despite
that the correct declaration is made. However, adjusting the
threshold value as described above allows avoiding the erroneous
determination.
(5) Output of Determination Result of Medication Administration
Declaration Reliability
[0087] When the medication administration declaration reliability
determination unit 14 terminates the determination of the
medication administration declaration reliability, the user
terminal UT activates the determination information output unit 15.
Then, under the control by the determination information output
unit 15, based on the determination result received from the
medication administration declaration reliability determination
unit 14, a notification message to notify the user himself/herself,
the medication administrator, such as the physician and the
pharmacist, or the family member of this determination result is
generated in step S17. Then, the notification message for the user
himself/herself is output to the input/display device 3 to be
displayed, and the notification message for the medication
administrator or the family member is output to the wireless
communication circuit 4 and transmitted from the wireless
communication circuit 4 to the terminal MT of the medication
administrator or the terminal FT of the family member. Note that in
this case, the notification message for the user may include a
"message that demands the medication administration itself"
together with a "message that prompts the correct declaration for
medication administration."
[0088] Note that, in this example, the case in which only the
determination information of the reliability of the medication
administration declaration is transmitted to the terminal MT of the
medication administrator or the terminal FT of the family member
has been described. This assumes the case that the medication
administration declaration information of the user has been
transmitted to the terminal MT of the medication administrator or
the terminal FT of the family member by another process. In
contrast, when the determination information of the reliability of
the medication administration declaration is transmitted to the
terminal MT of the medication administrator or the terminal FT of
the family member, the blood pressure measurement value itself may
be transmitted together. This allows, for example, the physician to
refer to it to, for example, examine the change of the
prescription. Alternatively, the medication administration
declaration information of the user corresponding to the same
determination target period may be transmitted to the terminal MT
of the medication administrator or the terminal FT of the family
member. At this time, the medication administration ratio may be
calculated from the medication administration declaration
information, and the calculated medication administration ratio may
be transmitted to the terminal MT of the medication administrator
or the terminal FT of the family member, together with the
declaration information or instead of the declaration
information.
[0089] Transmitting the declaration information of the medication
administration or the medication administration ratio along with
the determination result of the reliability of the declaration
information as described above allows, for example, the physician
and the pharmacist to make more accurate determination in
consideration of the reliability of the medication administration
declaration notified simultaneously when the medication
administration status of the user is determined from the medication
administration declaration information.
[0090] Further, to notify the medication administration ratio, the
medication administration ratio may be corrected (the true
medication administration ratio may be predicted) based on the
determination result of the reliability of the medication
administration declaration. As a method of the correction, for
example, it is considered that the medication administration ratio
based on the declaration information is reduced at a prescribed
percentage (for example, set to 70% of the declaration value).
[0091] Further, the determination process of the reliability by the
medication administration declaration reliability determination
unit 14 can be determined only by a distance from the threshold
value according to the declared medication administration ratio,
that is, an absolute value of the difference regardless of whether
the distance is large or small, as well as the determination
whether the degree of dispersion is larger than the threshold value
according to the declared medication administration ratio. This
makes it possible to determine that the reliability of the
declaration is low also in a case where the erroneous declaration
"not taken" is made despite that the medicine is actually
taken.
[0092] Further, for example, when the user forgets administering
the medication, the user possibly feels it is a burden to input
"not taken" and does not make the declaration itself. For this
reason, in a case where there is no declaration by the prescribed
percentage or more as described above, in addition to the case it
is processed as "no declaration," for example, a case where the
declaration has not been made may be regarded that the taking is
forgotten (that is, the declaration "not taken" has been made), and
the medication administration ratio and the reliability of the
declaration may be calculated.
[0093] Furthermore, in a case where the medication administration
declaration reliability determination unit 14 determines that "a
demand to the user for the medication administration declaration is
required," the following process is also conceivable. That is, the
determination information output unit 15 causes the user terminal
UT to display a message prompting the medication administration
declaration. The medication administration declaration reliability
determination unit 14 determines the presence/absence of a response
from the user to the transmission of the message prompting the
medication administration declaration, that is, whether the user
has performed the input operation of the medication administration
declaration information based on the acquisition result of the
declaration information by the medication administration
declaration information acquisition unit 11. In a case where it is
determined that the input operation of the declaration information
is not performed, it is regarded that the declaration for the
medication administration is not made, and the determination
process of the reliability of the declaration information is not
performed. In this way, the determination process of the
reliability of the declaration information in which the declaration
for medication administration is missing can be omitted, which
makes it possible to reduce the process load of the user terminal
UT.
Actions and Effects
[0094] Generally, the degree of dispersion of blood pressure values
is associated with the compliance status of the medication
administration. For example, seeing the degree of dispersion of
blood pressure values measured regularly every day in the target
period of one week, the degrees of dispersion of blood pressure
values of patients who comply with the medication administration
tend to be small, and conversely, the degrees of blood pressure
values of patients who do not comply with the medication
administration tend to be large.
[0095] Thus, in the first embodiment, the medication administration
declaration information acquisition unit 11 receives the input of
the medication administration declaration information by the user,
and concurrently the blood pressure measurement data acquisition
unit 12 acquires the blood pressure measurement data of the user
from the blood pressure monitor BP and stores it, the dispersion
degree calculation unit 13 calculates the degree of dispersion of
blood pressure values in the determination target period based on
the stored blood pressure measurement data, the medication
administration declaration reliability determination unit 14
determines the reliability of the medication administration
declaration information declared in the same period based on the
degree of dispersion of the blood pressure measurement values, and
the determination information output unit 15 transmits the
determination result to, for example, the terminal MT of the
medication administrator.
[0096] Therefore, the medication administrator, such as the
physician or the pharmacist, can accurately infer the status of the
medication administration of the user as the patient and determine
the effect of the medication. In addition, when the determination
result of the reliability is transmitted to the terminal FT of, for
example, the family member, the family member can directly guide
the user himself/herself regarding the declaration for medication
administration and confirm whether the medication administration is
adequately performed. Further, by displaying the message that
demands the declaration for medication administration on the
input/display device 3 for the user who tends to forget the
declaration for medication administration, a compliance proportion
of the medication administration declaration by the user can be
increased.
Second Embodiment
[0097] In the second embodiment according to the present invention,
a subsequent change in the blood pressure is predicted based on the
blood pressure measurement data obtained in a past period in which
the medication administration status is known, a degree of
divergence between the predicted value of the blood pressure and
the actually measured value of the blood pressure actually measured
is calculated, and reliability of the medication administration
declaration information in a medication administration period that
affects the blood pressure value in the period in which this degree
of divergence is calculated is determined.
[0098] For example, based on whether the medication administration
ratio is known or the reliability, a period in which the medication
administration ratio is corrected is selected as a predicted
reference period of blood pressure variation (hereinafter also
referred to as a first period). Then, the subsequent blood pressure
variation is predicted based on the blood pressure measurement data
obtained during the first period, and the degree of divergence
between the predicted blood pressure value and the actually
measured blood pressure value actually measured in the period of
the monitoring target of the blood pressure value (hereinafter also
referred to as a second period). Based on the calculated degree of
divergence of the blood pressure value, the reliability of the
medication administration declaration information of the user in a
medication administration period prior to the second period
(hereinafter, also referred to as a third period) that affects the
blood pressure value (that is, medical efficacy appears) in the
second period is determined.
[0099] Note that to select the first period, in a case where a
period in which the medication administration of the user is
accurately managed, such as a period of hospital treatment, is
present, this period may be selected as the first period.
Furthermore, in a case where a medicine having a quick effect is
prescribed or in a case where the user has a physical constitution
on which a medicine easily acts, the third period as the
determination target period of reliability can be set to be same as
the second period, which is the monitoring target period of the
degree of divergence.
[0100] Further, the first period and the second or third period
need not be continuous, and far from it, the periods are preferably
not continuous. This is because when the first period is continuous
with the second or third period, the degree of change in blood
pressure value and the degree of divergence are too small and
therefore it is predicted that the comparison cannot be
performed.
[0101] In addition, in a case where the first period and the second
or third period are continuous, ensuring a certain amount of length
or more for each period is preferred. This is because this allows
reducing an influence from a natural blood pressure variation and
an error. In particular, the degree of divergence can be calculated
in theory by the use of only the actually measured blood pressure
value measured at a certain one timing in the second period.
However, to eliminate an influence of the natural blood pressure
variation and the error, including a plurality of times of the
actually measured blood pressure values is desirable.
Configuration Example
[0102] A system in which the medication administration status
management device according to the second embodiment is used has a
basic configuration same as that of the first embodiment, and thus
the description thereof will be omitted. A hardware configuration
of the user terminal UT as the medication administration status
management device is also the same as that described in the first
embodiment, and thus the description thereof will be omitted.
(1) User Terminal UT
(1-1) Software Configuration
[0103] FIG. 7 is a block diagram illustrating the software
configuration of the user terminal UT.
[0104] The data storage area in a memory 6 includes a medication
administration/blood pressure information storage unit 61 and a
prescription information storage unit 62. The medication
administration/blood pressure information storage unit 61 stores
the input template data used when the user inputs the declaration
information of the medication administration. The medication
administration/blood pressure information storage unit 61 also
stores the declaration information of the medication administration
input by the user based on the input template data associated with
information representing the date and time of the medication
administration. Furthermore, the medication administration/blood
pressure information storage unit 61 stores the measurement data of
the blood pressure, which is transmitted from the blood pressure
monitor BP, associated with information representing the date and
time of the measurement. The prescription information storage unit
62 stores prescription information of the target user downloaded
from the terminal MT of the medication administrator, such as the
physician or the pharmacist, or the EMR server of, for example, a
medical institution.
[0105] A CPU 5 includes a medication administration declaration
information acquisition unit 51, a blood pressure measurement data
acquisition unit 52, a blood pressure change prediction unit 53, a
blood pressure comparison unit 54, a medication administration
declaration reliability determination unit 55, and a determination
information output unit 56 as process function units according to
the second embodiment. These control units 51 to 56 are all
achieved by causing the CPU 5 to execute the application program
stored in the program memory area in the memory 6.
[0106] The medication administration declaration information
acquisition unit 51 is activated by the input request operation of
the medication administration declaration by the user, reads the
input template data from the medication administration/blood
pressure information storage unit 61, and causes the input/display
device 3 to display the input template data. Then, the medication
administration declaration information acquisition unit 51 performs
a process that receives the declaration information of the
medication administration input by the user in accordance with the
guidance of the input template data from the input/display device 3
and causes the medication administration/blood pressure information
storage unit 61 to store the declaration information.
[0107] Note that the medication administration declaration
information includes, for example, information representing the
date and time of the medication administration and information
representing the presence or absence of the medication
administration on the date and time. For example, in a case where
the medication administration timings are designated at, for
example, after breakfast, after lunch, after dinner, at wakeup, and
at bedtime in the prescription, the information representing the
date and time of the medication administration is represented by
these pieces of information representing the medication
administration timings. The information representing the presence
or absence of the medication administration is input for each type
of the medicine in the case where there are multiple types of
medicines to be administered.
[0108] The blood pressure measurement data acquisition unit 52 is
activated, for example, by the data transmission request from the
blood pressure monitor BP, and performs a process that causes the
medication administration/blood pressure information storage unit
61 to store the blood pressure measurement data transmitted from
the blood pressure monitor BP and received by the wireless
communication circuit 4 together with the information representing
the date and time of the measurement. Additionally, at this time,
the blood pressure measurement data acquisition unit 52 stores the
blood pressure measurement data and the medication administration
declaration information such that the blood pressure measurement
data and the medication administration declaration information
whose date and time of the measurement and date and time of the
medication administration correspond to each other are
associated.
[0109] The blood pressure change prediction unit 53 first selects
the past period in which the medication administration status is
known as the predicted reference period (the first period) of the
blood pressure variation. Then, the blood pressure change
prediction unit 53 performs a process that reads the blood pressure
measurement data obtained in the first period from the medication
administration/blood pressure information storage unit 61 and
predicts a subsequent change in the blood pressure value from the
blood pressure measurement data.
[0110] For example, the blood pressure change prediction unit 53
reads the medication administration declaration information in the
first period from the medication administration/blood pressure
information storage unit 61, calculates the medication
administration ratio based on the medication administration
declaration information, and reflects the medication administration
ratio to the predicted value of the blood pressure value. In other
words, a process of correcting the predicted value of the blood
pressure value based on the medication administration ratio during
the first period is also performed.
[0111] The blood pressure comparison unit 54 sets, for example, the
most recent monitoring target period of the blood pressure value
(the second period). Then, the blood pressure comparison unit 54
performs a process that reads the blood pressure measurement data
(the actually measured value of the blood pressure) obtained in the
second period from the medication administration/blood pressure
information storage unit 61 and calculates the degree of divergence
of the actually measured value of the blood pressure with respect
to the predicted value of the blood pressure in the second period
obtained by the blood pressure change prediction unit 53.
[0112] Based on the degree of divergence of the blood pressure
calculated by the blood pressure comparison unit 54, the medication
administration declaration reliability determination unit 55
performs a process that determines the reliability of the
medication administration declaration information in the medication
administration period (the third period), which is prior to the
second period, whose medical efficacy appears in the blood pressure
value in the second period, for example. An example of the
reliability determination will be described later.
[0113] The determination information output unit 56 performs a
process that generates notification information for notifying the
medication administrator, the family member of the user, or the
user himself/herself of the determination result of the reliability
of the medication administration declaration information by the
medication administration declaration reliability determination
unit 55, and transmits the notification information to the
medication-administrator terminal MT or the terminal FT of the
family member, or causes the input/display device 3 to display the
notification information.
Operation Example
[0114] Next, operations of the user terminal UT configured as
described above will be described. FIG. 8 and FIG. 9 are flowcharts
exemplifying the operations.
(1) Acquisition of Medication Administration Declaration
Information
[0115] The user terminal UT monitors the operation of the input
request for the medication administration declaration information
in a standby state in step S20. In this state, assume that the user
has performed the tap operation on the icon to which, for example,
the medication administration declaration function is assigned in
the input/display device 3. Then, the user terminal UT activates
the medication administration declaration information acquisition
unit 51, and first reads the input template data from the
medication administration/blood pressure information storage unit
61 and causes the input/display device 3 to display the input
template data in step S21.
[0116] In this state, for example, when the user inputs the
presence or absence of the medication administration after
breakfast, after lunch, and after dinner on the day in accordance
with the input template, the input information representing the
presence or absence of the medication administration at each meal
is received from the input/display device 3 and the medication
administration/blood pressure information storage unit 61 is caused
to store the information. At this time, information representing
date and time at which the medication was administered or date and
time at which the medication should be administered (hereinafter
collectively referred to as date and time of the medication
administration) is given to each piece of the information
representing the presence or absence of the medication
administration.
[0117] For example, some users possibly input the declaration for
the medication administration for one day at once after dinner,
before going to bed, or the next day or later. In such a case, in a
case where the date and time of the input (the date and time of the
declaration) is directly regarded as the date and time of the
medication administration, the date and time of the declared
medication administration differs from the true date and time of
the medication administration.
[0118] Therefore, for example, as illustrated in FIG. 10 as an
example, the input template includes the checkboxes 31a, 32a, and
33a for inputting the presence or absence of the medication
administration, and the input fields 31b, 32b, and 33b for the time
of the medication administration corresponding to each of after
breakfast, after lunch, and after dinner described above about a
date and time when the inputs are not performed. Then, the
medication administration declaration information storage unit 21
is caused to store the information representing the presence or
absence of the medication administration and the information
representing the medication administration time input to the
corresponding checkboxes 31a, 32a, and 33a and input fields 31b,
32b, and 33b for each of the breakfast, the lunch, and the dinner
as the medication administration declaration information.
[0119] After that, each time the user performs the input request
operation of the medication administration declaration, under the
control of the medication administration declaration information
acquisition unit 51, the user terminal UT performs a process that
receives the above-described medication administration declaration
information and causes the medication administration declaration
information storage unit 21 to store it.
(2) Acquisition of Blood Pressure Measurement Data
[0120] In the standby state, the user terminal UT monitors the
transmission request for the blood pressure measurement data from
the blood pressure monitor BP in step S52. In this state, when
receiving the transmission request for the blood pressure
measurement data from the blood pressure monitor BP, the user
terminal UT activates the blood pressure measurement data
acquisition unit 52, takes in the blood pressure measurement data
transmitted from the blood pressure monitor BP and received by the
wireless communication circuit 4 from the wireless communication
circuit 4, and causes the medication administration/blood pressure
information storage unit 61 to store the measurement blood pressure
data in step S23. At this time, since the information representing
the date and time of the measurement is transmitted along with the
blood pressure measurement data, the user terminal UT associates
the blood pressure measurement data with the date and time of the
measurement, and further associates it with the medication
administration declaration information to which the date and time
of the medication administration corresponds, and causes the
medication administration/blood pressure information storage unit
61 to store it.
[0121] Thereafter, each time the user terminal UT receives the
transmission request from the blood pressure monitor BP, the user
terminal UT performs reception and storage processes of the
above-described blood pressure measurement data under the control
by the blood pressure measurement data acquisition unit 52.
(3) Prediction of Blood Pressure Change
[0122] The user terminal UT monitors a determination request for
medication administration declaration reliability while performing
the acquisition process of the medication administration
declaration information and the acquisition process of the blood
pressure measurement data in step S24. In this state, for example,
when the user terminal UT receives a determination request from the
terminal MT of the medication administrator, such as the physician
or the pharmacist, or the terminal FT of the family member, the
user terminal UT activates the blood pressure change prediction
unit 53.
[0123] Under the control by the blood pressure change prediction
unit 53, for example, the user terminal UT first selects the past
period in which the medication administration status is known as
the predicted reference period (the first period) of the blood
pressure variation in step S25. Then, the user terminal UT reads
the medication administration declaration information and the blood
pressure measurement data in the first period (for example, one day
or one week) from the medication administration/blood pressure
information storage unit 61. Then, the user terminal UT calculates,
for example, the medication administration ratio in the medication
administration period based on the medication administration
declaration information, and predicts the subsequent change in the
blood pressure value from the blood pressure measurement data in
the medication administration period considering the medication
administration ratio. That is, based on the blood pressure value
measured in the first period in which the medication administration
ratio is known, the change in the blood pressure value in the
subsequent period is predicted.
[0124] Note that, for example, the blood pressure value is
predicted by acquiring guideline data representing the change in
the blood pressure value with respect to a dosage for a standard
patient from a database, such as the Electronic Medical Records
(EMR) server, and referring to the data of this guideline, or using
a learning model that learnt the change in the blood pressure based
on the past dosage and blood pressure variation history of the
user. In addition, in a case where a period in which the medication
was surely administered is apparent or a period in which it is
apparent that the medication administration ratio is correct due to
a reason, such as hospital treatment was performed, is present,
this period may be used as the first period described above.
(4) Calculation of Degree of Divergence of Blood Pressure
[0125] The user terminal UT subsequently activates the blood
pressure comparison unit 54. Under the control by this blood
pressure comparison unit 54, the most recent blood pressure
monitoring target period (for example, one day, today) is first
selected as the second period, and the blood pressure measurement
data (the actually measured value of the blood pressure) in the
second period is read from the medication administration/blood
pressure information storage unit 61 in step S26. Then, among the
predicted values of the blood pressure obtained by the blood
pressure change prediction unit 53, the degree of divergence (for
example, a difference) of the actually measured value of the blood
pressure with respect to the predicted blood pressure value
obtained in the second period is calculated.
[0126] Note that, in the calculation of the degree of divergence,
the actually measured value of the blood pressure at a certain time
point during the second period may be compared with the predicted
value, but the average value of the actually measured blood
pressure values measured at a plurality of timings during the
second period may be compared with the predicted value. In this
way, an influence of temporal blood pressure variations can be
reduced.
(5) Determination of Medication Administration Declaration
Reliability
[0127] When the degree of divergence of the blood pressure value in
the second period is calculated, the user terminal UT then
activates the medication administration declaration reliability
determination unit 55. Then, under the control by the medication
administration declaration reliability determination unit 55, in
step S27, the medication administration period (for example,
yesterday or today) that affects the blood pressure value in the
second period, that is, whose medical efficacy appears in the
second period is defined as the third period, and the medication
administration declaration information in the third period is read
from the medication administration/blood pressure information
storage unit 61. Then, the read reliability of the medication
administration declaration information of the third period read is
determined based on the degree of divergence of the blood pressure
in the second period calculated by the blood pressure comparison
unit 54.
[0128] FIG. 9 is a flowchart depicting an example of a procedure
and a process content of the determination process of the
medication administration declaration reliability. The medication
administration declaration reliability determination unit 55 first
reads the medication administration declaration information in the
third period from the medication administration/blood pressure
information storage unit 61 and determines whether any medication
administration declaration has been made based on the medication
administration declaration information in step S271. In other
words, the presence or absence of a missing in the medication
administration declaration is determined.
[0129] For example, in a case where the third period is one day,
insofar as there is at least one medication administration timing
at which the medication administration declaration is not made
among the medication administration timings designated in the
prescription information stored in the prescription information
storage unit 62, the medication administration declaration is
determined as absent in the day. For example, when the medication
administration timing is designated three times, after breakfast,
after lunch, and after dinner, and it is declared that taking the
medicine is forgotten (no medication administration) after dinner,
the medication administration declaration is determined as absent
in the day. For example, in a case where the third period is one
week, when the number of days in which the medication
administration declaration is not made at all is one day or more or
the prescribed number of days or more, it is determined that the
medication administration declaration is absent in this week. In
the case where the medication administration declaration is
determined as absent, the medication administration declaration
reliability determination unit 55 regards that the medication
administration declaration information in the third period is out
of the determination target of the medication administration
declaration reliability, determines that "a demand to the user for
the medication administration declaration is required," and passes
the determination result to the determination information output
unit 56 in step S272.
[0130] On the other hand, when the medication administration
declaration is determined as present in the step S271, the
medication administration declaration reliability determination
unit 55 next determines whether the degree of divergence of the
blood pressure value (a difference between the predicted value of
the blood pressure and the actually measured value) calculated by
the blood pressure comparison unit 54 is greater than or equal to a
threshold value in step S273. As a result of the determination, in
the case of the degree of divergence of the blood pressure value
being greater than or equal to the threshold value, the medication
administration declaration reliability determination unit 55
determines that the reliability of the medication administration
declaration information in the third period is "low" in step S274.
In contrast, in the case of the degree of divergence of the blood
pressure value being less than the threshold value, the medication
administration declaration reliability determination unit 55
determines that the reliability of the medication administration
declaration information in the third period is "high" in step
S275.
(6) Output of Determination Result of Medication Administration
Declaration Reliability
[0131] When the medication administration declaration reliability
determination unit 55 terminates the determination process of the
medication administration declaration reliability, the user
terminal UT activates the determination information output unit 56.
Then, under the control by the determination information output
unit 56, based on the determination result received from the
medication administration declaration reliability determination
unit 55, a notification message to notify the user himself/herself,
the medication administrator, such as the physician and the
pharmacist, or the family member of this determination result is
generated in step S28. Then, the notification message for the user
himself/herself is output to the input/display device 3 to be
displayed, and the notification message for the medication
administrator or the family member is output to the wireless
communication circuit 4 and transmitted from the wireless
communication circuit 4 to the terminal MT of the medication
administrator or the terminal FT of the family member.
[0132] Note that, in this example, the case in which only the
determination information of the reliability of the medication
administration declaration is transmitted to the terminal MT of the
medication administrator or the terminal FT of the family member
has been described. This assumes the case that the medication
administration declaration information of the user has been
transmitted to the terminal MT of the medication administrator or
the terminal FT of the family member by another process. In
contrast, when the determination information of the reliability of
the medication administration declaration is transmitted to the
terminal MT of the medication administrator or the terminal FT of
the family member, the medication administration declaration
information of the user corresponding to the same medication
administration period (the third period) may be transmitted
together to the terminal MT of the medication administrator or the
terminal FT of the family member FT. At this time, the medication
administration ratio may be calculated from the declaration
information, and the calculated medication administration ratio may
be transmitted to the terminal MT of the medication administrator
or the terminal FT of the family member, together with the
declaration information or instead of the declaration
information.
[0133] Transmitting the declaration information of the medication
administration or the medication administration ratio along with
the determination result of the reliability of the declaration
information as described above allows, for example, the physician
and the pharmacist to make more accurate determination in
consideration of the reliability of the medication administration
declaration notified simultaneously when the medication
administration status of the user is determined from the medication
administration declaration information.
[0134] Further, to notify the medication administration ratio, the
medication administration ratio may be corrected (the true
medication administration ratio may be predicted) based on the
determination result of the reliability of the medication
administration declaration. As a method of the correction, for
example, it is considered that the medication administration ratio
based on the declaration information is reduced at a prescribed
percentage (for example, set to 70% of the declaration value).
[0135] Further, the determination process of the reliability by the
medication administration declaration reliability determination
unit 55 can be determined only by a distance from the threshold
value according to the declared medication administration ratio,
that is, an absolute value of the difference regardless of whether
the distance is large or small, as well as the determination
whether the degree of divergence of the blood pressure is larger
than the threshold value according to the declared medication
administration ratio. This makes it possible to determine that the
reliability of the declaration is low also in a case where the
erroneous declaration "not taken" is made despite that the medicine
is actually taken.
[0136] Further, for example, when the user forgets administering
the medication, the user possibly feels burdensome to input "not
taken" and does not make the declaration itself. For this reason,
in a case where there is no declaration by the prescribed
percentage or more as described above, in addition to the case it
is processed as "no declaration," for example, a case where the
declaration has not been made may be regarded that the taking is
forgotten (that is, the declaration "not taken" has been made), and
the medication administration ratio and the reliability of the
declaration may be calculated.
[0137] Furthermore, in a case where the medication administration
declaration reliability determination unit 14 determines that "a
demand to the user for the medication administration declaration is
required," the following process is also conceivable. That is, the
determination information output unit 15 causes the user terminal
UT to display a message prompting the medication administration
declaration. The medication administration declaration reliability
determination unit 14 determines the presence/absence of a response
from the user to the transmission of the message prompting the
medication administration declaration, that is, whether the user
has performed the input operation of the medication administration
declaration information based on the acquisition result of the
declaration information by the medication administration
declaration information acquisition unit 11. In a case where it is
determined that the input operation of the declaration information
is not performed, it is regarded that the declaration for the
medication administration is not made, and the determination
process of the reliability of the declaration 3o information is not
performed. In this way, the determination process of the
reliability of the declaration information in which the declaration
for medication administration is missing can be omitted, which
makes it possible to reduce the process load of the user terminal
UT.
Actions and Effects
[0138] Generally, the difference between the predicted value and
the actually measured value of the blood pressure of the user who
complies with the medication administration is considered as small.
Therefore, the degree of divergence between the predicted value of
the blood pressure in the most recent blood pressure monitoring
period (the second period), which is predicted from the blood
pressure values measured in the past predicted reference period
(the first period) in which the medication administration ratio is
known and the actually measured value of the blood pressure value
actually measured during the second period tends to be small. In
contrast, in a case where the user who does not comply with the
medication administration declares for medication administration as
if the user complied with the medication administration, it is
inferred that the degree of divergence between the predicted blood
pressure value and the actually measured value of the blood
pressure actually measured actually measured in the second period
in which the medical efficacy should appear becomes large.
[0139] Thus, in the second embodiment, the blood pressure change
prediction unit 53 predicts the change in the blood pressure in the
most recent blood pressure monitoring period (the second period)
based on the blood pressure measurement data measured in the past
predicted reference period (the first period) in which the
medication administration ratio is known, and the blood pressure
comparison unit 54 calculates the degree of divergence between the
predicted value of the blood pressure and the actually measured
value of the blood pressure, which was actually measured in the
second period. Based on the calculated degree of divergence of the
blood pressure, the medication administration declaration
reliability determination unit 55 determines the reliability of the
medication administration declaration information in the medication
administration period (the third period), which is prior to the
second period, that affects the blood pressure value (the medical
efficacy appears) in the second period, and outputs information
representing the determination result to, for example, the terminal
MT of the medication administrator by the determination information
output unit 56.
[0140] Thus, the medication administrator, such as the physician or
the pharmacist, can more accurately infer the status of the
medication administration during the previous medication
administration period that affects the blood pressure in the most
recent blood pressure monitoring period of the user as the patient,
to determine the effect of the medication. In addition, when the
determination result of the reliability of the medication
administration declaration is transmitted to the terminal FT of,
for example, the family member, the family member can directly
guide the user himself/herself regarding the declaration for
medication administration and confirm whether the medication
administration is adequately performed. Further, by displaying the
message that demands the declaration for medication administration
on the input/display device 3 for the user who tends to forget the
declaration for medication administration, a compliance proportion
of the medication administration declaration by the user can be
increased.
Modified Examples
[0141] (1) The reliability of the medication administration
declaration determined in the period of the determination target of
the medication administration declaration reliability, that is, the
target period in the first embodiment or the third period in the
second embodiment, may be regarded to be tentatively continued
until the reliability of the medication administration declaration
is determined next, that is, may be held for a period after the
target period or the third period until the present including the
second period in the second embodiment. This can be achieved as
follows. The medication administration declaration reliability in
the target period or the third period determined by the medication
administration declaration reliability determination unit 14 or 55
is stored in a reliability storage unit (not illustrated) in the
memory 2 until the determination process of the reliability is
performed next by the medication administration declaration
reliability determination unit 14 or 55, and is updated each time
new reliability is obtained.
[0142] (2) In the first and second embodiments, the example in
which the management function of the medication administration
status according to the present invention is provided in the user
terminal UT has been described. However, the present invention is
not limited thereto. For example, the management function of the
medication administration status according to the present invention
may be provided in a server device operated by a medical
institution, such as a hospital and a pharmacy, or in a server
device operated by a service operator related to, for example, a
medical treatment, a medicinal drug, or a nursing care.
[0143] In such a manner, in a case that the server device is
provided with the management function of the medication
administration status, for example, the medication administration
declaration information input by the user in the user terminal and
the biological information measured by the blood pressure monitor
can be transmitted from the user terminal to the server device at
each fixed period. The server device can receive and store the
medication administration declaration information and the
biological information transmitted from the user terminal and
perform a series of processes described in the first and second
embodiments according to the preset determination timing or the
input of the determination request from, for example, the
physician.
[0144] (3) In the first and second embodiments, an example in which
the function of the medication administration status management
device is provided on the mobile information terminal (the user
terminal), such as a smartphone, possessed by the user has been
described, However, for example, the function of the medication
administration status management device including a blood pressure
measurement function may be provided in a wearable terminal.
[0145] (4) In the first and second embodiments, the reliability of
the medication administration declaration information is determined
by comparing the degree of dispersion of the blood pressure value
or the degree of divergence of the actually measured value with
respect to the predicted value of the blood pressure with one
threshold value. However, no such limitation is intended, for
example, a plurality of threshold values may be set and the degree
of dispersion of the blood pressure value or the degree of
divergence of the actually measured value with respect to the
predicted value of the blood pressure may be compared with the
plurality of threshold values to determine the reliability of the
medication administration declaration information in multiple
stages.
[0146] (5) In the first and second embodiments, the case in which
blood pressure measurement data is acquired as the biological
information has been described as an example, but measurement data
of a blood glucose level, a uric acid level, a creatinine level, a
cholesterol level, and a blood oxygen saturation concentration
(SPO2) and further measurement data of, for example, a weight, a
waist circumference, and a body fat percentage may be acquired, the
degree of dispersion or the degree of divergence from the predicted
value may be calculated, and the reliability in the medication
administration declaration information may be determined based on
the result.
[0147] (6) In addition, for example, the configuration, the process
procedure, and the a process content of the medication
administration status management device, the constitution and the
notification destination of the information representing the
determination result of the reliability of the medication
administration declaration information, a selection method and a
length of each first, second, and third period described in the
second embodiment can be modified and embodied in various ways
within a scope not departing from the gist of the present
invention.
[0148] While the plurality of embodiments and the modified examples
according to the present invention have been described in detail
above, the above-described description is merely examples of the
present invention in all respects, and obviously, various
improvements and modifications can be made without departing from
the scope of the present invention. That is, specific
configurations according to the respective embodiment may be
employed as appropriate in the implementation of the present
invention.
[0149] Additionally, in the present invention, various inventions
can be formed by appropriately combining a plurality of components
disclosed in the embodiments described above. For example, some
components may be omitted from all the components described in the
respective embodiments.
[0150] Further, the components of the different embodiments may be
combined appropriately.
Supplementary Notes
[0151] A portion or all of the embodiments can be described as
described in the following supplementary notes in addition to the
scope of the claims, but is not limited to the supplementary
notes.
Supplementary Note 1
[0152] A medication administration status management device that
includes a hardware processor and a storage medium. The hardware
processor is configured to perform: a process that acquires
declaration information regarding medication administration of a
user; a process that acquires biological information of the user
and causes the storage medium to store the biological information;
a process that calculates a degree of dispersion of the biological
information acquired in a target period based on the biological
information stored in the storage medium; a process that determines
reliability of the declaration information regarding the medication
administration acquired in the target period based on the degree of
dispersion of the biological information; and a process that
outputs information representing a determination result of the
reliability.
Supplementary Note 2
[0153] A medication administration status management device that
includes a hardware processor and a storage medium. The hardware
processor is configured to perform: a process that acquires
declaration information regarding medication administration of a
user and causes the storage medium to store the declaration
information; a process that acquires biological information of the
user and causes the storage medium to store the biological
information in a state in which the biological information is
associable with the declaration information having a corresponding
acquisition timing; a process that calculates a predicted value of
the biological information in a second period in which the
biological information is a monitoring target based on the
declaration information and the biological information in a first
period in which a medication administration status is known and
stored in the storage medium; a process that calculates a degree of
divergence of an actually measured value of the biological
information acquired during the second period with respect to the
calculated predicted value of the biological information; a process
that determines reliability of the declaration information
regarding the medication administration in a third period that
affects a change in the biological information in the second period
based on the calculated degree of divergence, the third period
being prior to the second period; and a process that outputs
information representing a determination result of the
reliability.
REFERENCE SIGNS LIST
[0154] UT Mobile information terminal [0155] BP Blood pressure
monitor [0156] NW Network [0157] MT Medication-administrator
terminal [0158] FT Family terminal [0159] 1, 5 CPU [0160] 2, 6
Memory [0161] 3, 100 Input/display device [0162] 4, 700 Wireless
communication circuit [0163] 11, 51, 400 Medication administration
declaration information acquisition unit [0164] 12, 52, 200 Blood
pressure measurement data acquisition unit [0165] 13, 300
Dispersion degree calculation unit [0166] 14, 55, 500 Medication
administration declaration reliability determination unit [0167]
15, 56, 600 Determination information output unit [0168] 21
Medication administration declaration information storage unit
[0169] 22 Blood pressure measurement data storage unit [0170] 41
Antenna [0171] 53 Blood pressure change prediction unit [0172] 54
Blood pressure comparison unit [0173] 61 Medication
administration/blood pressure information storage unit
* * * * *